THE 2014 AnnuAl MEETInG - BMES

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B i o med i cal E n g i n eer i n g S o c i ety Advancing Human Health and Well Being

BMES Officers President Gilda Barabino, PhD The City College of New York

8201 Corporate Drive, Suite 1125 Landover, MD 20785-2224 Phone: 301-459-1999 Fax: 301-459-2444 Web: www.bmes.org

Incoming President Richard T. Hart, PhD The Ohio State University

BMES Staff

Secretary

Edward L. Schilling, III

David A.Vorp, PhD

Executive Director

University of Pittsburgh

Doug Beizer

Treasurer Jennifer West, PhD Duke University

Publications Board Chair Frank C. P. Yin, MD, PhD

Future BMES Annual Meetings October 7-10, 2015

Communications Director

Michele S. Ciapa, MPH, CHES Education Director Membership Director

October 11-14, 2017

Valerie A. Kolmaister Operations and Finance Director

Finance Committee Chair

Meetings Director

Raphael C. Lee, MD, ScD, FACS

Terry Young

Atlanta, Georgia

BMES Career Connections Director

BMES Board of Directors

Student Affairs Manager

2011-2014 Directors

Meetings Manager and Registrar

Clemson University

Kristina Ropella, PhD Marquette University

Phoenix, Arizona

October 17-20, 2018

Debra Tucker, CMP

Elizabeth DaSilva

Martine LaBerge, PhD

October 5-8, 2016 Minneapolis, Minnesota

Jennifer Edwards

Washington University in St. Louis

The University of Chicago

Tampa, Florida

Leticia Marquez Lori Saskiewicz

October 16-19, 2019 Philadelphia, Pennsylvania

October 14-17, 2020 San Diego, California

October 6-9, 2021

Membership Assistant

Orlando, Florida

Betse Lyons Administrative Assistant

Christine Schmidt, PhD University of Florida

Joyce Wong, PhD

Media Contact

Boston University

Doug Beizer [email protected], 410 -814-9564

2012-2015 Directors Ravi Bellamkonda, PhD Georgia Institute of Technology

Kristen Billiar, PhD Worcester Polytechnic Institute

Scott L. Diamond, PhD University of Pennsylvania

Jane Grande-Allen, PhD Rice University

2013-2016 Directors Ed Botchwey, PhD Georgia Institute of Technology

Deborah Leckband, PhD University of Illinois, Urbana-Champaign

Cato Laurencin, MD, PhD University of Connecticut

William Reichert, PhD

Social Media: BMES 2014 Please share your comments, photos & videos! www.facebook.com/BMESociety @BMESociety Please use the hashtag #BMES2014

Duke University

Student Representative

www.youtube.com/BMESociety

Rebecca Scott Purdue University

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Table of COntents

Table of Contents

BMES Leadership & Staff . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1

Scientific Program

Sponsors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4

THURSDAY

Welcome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5

Platform Sessions Th-1 (Thursday 8:00-9:30am). . . . . . . . . . . . . . . . . . . . . . 71-77 Platform Sessions Th-2 (Thursday 2:00-3:30pm). . . . . . . . . . . . . . . . . . . . . . 78-84

Meeting Chairs. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6-7

Platform Sessions Th-3 (Thursday 4:30-6:000pm). . . . . . . . . . . . . . . . . . . . . 85-91

Plenary Sessions

Poster Sessions – Thursday. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93-124

Pritzker Distinguished Lecture. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8

FRIDAY

Medical Devices SIG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9

Platform Sessions Fri-1 (Friday 8:00-9:30am). . . . . . . . . . . . . . . . . . . . . . . 125-131

NIH - NIBIB Lecture . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10

Platform Sessions Fri-2 (Friday 1:45-2:45pm) . . . . . . . . . . . . . . . . . . . . . . 132-136

Special Plenary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11

Platform Sessions Fri-3 (Friday 3:00-4:00pm) . . . . . . . . . . . . . . . . . . . . . . 137-140

Rita Schaffer Memorial Lecture. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12

Poster Sessions – Friday. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142-173

Diversity Lecture. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13

Exhibits & Poster Session Floorplan. . . . . . . . . . . . . . . . . 17-48 General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 Presenter Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50

SATURDAY Platform Sessions Sat-1 (Saturday 8:00am-9:30am). . . . . . . . . . . . . . . . . 174-181 Platform Sessions Sat-2 (Saturday 1:30-3:00pm). . . . . . . . . . . . . . . . . . . .182-188 Platform Sessions Sat-3 (Saturday 3:15-4:45pm). . . . . . . . . . . . . . . . . . . .189-193 Poster Sessions – Saturday . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195-210

Program Highlights. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 Luncheons. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 Additional Meetings. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53 Hosted Receptions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 Student and Early Career Programs. . . . . . . . . . . . . . . . . 56-60 2014 Award Recipients. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 Track Chairs & Reviewers . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64-68 Convention Center Floorplan . . . . . . . . . . . . . . . . . . . . . . . . . 211 Program at a Glance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212-217 Schedule at a Glance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218-221

AUTHOR INDEX

Available on the Mobile App Available at http://submissions.miracd.com/bmes2014/itinerary Copies also available at the registration desk.

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BMES 2014 Annual Meeting Sponsors Thank you for our sponsors' generous support: platinum

Gold

Silver

Thank you to our other supporters: Grants have been provided by the National Institute of Biomedical Imaging and Bioengineering and the National Science Foundation for the BMES 2014 Annual Meeting.

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BMES 2014 Meeting Welcome

Gilda A. Barabino, PhD BMES President Dean, Grove School of Engineering The City College of New York

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elcome to the 2014 Annual Meeting of the Biomedical Engineering Society! Our Annual Meeting is the premier event for the Society and the field of biomedical engineering. This year’s theme, “Bioengineering Innovations to Catalyze Affordable Health Care,” encompasses the breadth of research and education biomedical engineers are involved in toward advancing human health and well being. I

urge you to take full advantage of the excellent technical program, plenaries, special events and myriad opportunities for professional development and networking. The President’s Address on the State of the Society will be given at the plenary on Thursday morning and will provide attendees the opportunity to learn about future directions for the Society including new initiatives enabled by our generous $1 million gift from the Coulter Foundation announced at last year’s meeting. BMES 2014 marks the continuation of long-standing traditions and newly established programs to illuminate innovations, recognize achievements, celebrate diversity and develop future biomedical engineers. Coulter College, a training program focused on the translation of biomedical innovations, is partnering with BMES for the third consecutive year. During Coulter College teams participate in a two-and-a-half day workshop focusing on preparing students for translational work.

Capitalizing on the success of the last two year’s sessions dedicated to health disparities, this year’s session, “Diversity, Health Disparities and Affordable Healthcare” offers to help better inform the broader BME community about health disparities and inequities—and the role biomedical engineers can play in combating them. The session will provide a context for examining health disparities in translational research and discuss historical examples of differential medical treatment and civil rights infringements based on race and ethnicity. Emphasis will be placed on achieving enhanced and affordable healthcare through engineering technologies. BMES 2014 marks the third year of our partnership with NIH NIBIB to deliver the NIBIB Lecture and the DEBUT Awards and our second year of partnering with NSF. This year’s BMES-NSF session, "Research in Biomedical Engineering and Grant Writing" will showcase NSF-funded research and researchers, foster collaboration and idea exchange, familiarize participants with NSF funding mechanisms, and provide strategies for preparing competitive grant proposals (in particular, NSF CAREER grant applications). Our three Special Interest Groups: Cellular and Molecular Bioengineering (CMBE), Medical Devices, and Advanced BioManufacturing (ABioM) will all hold business meetings during the conference. The Medical Devices SIG will conduct a Thursday afternoon Plenary session entitled “Computational Modeling and Simulation for Medical Devices” and the ABioM will convene a special session on Saturday morning on “Advanced Biomanufacturing: Application towards the Next Generation Therapies and Diagnostics." Formal and informal career development opportunities are abundant throughout the meeting starting with a slate of student and early career sessions on career pathways available Thursday and Friday. We are now over 7,000 members strong and the involvement of our members at the meeting and throughout the year enables us to continue our unprecedented growth and development. Special thanks are due to Conference Chair, John A. White, and Program Chair, Susan Margulies, BMES Staff, NSF, NIH, Coulter Foundation, our sponsors and our meeting attendees. My very best wishes to you for an enjoyable and productive meeting! Gilda A. Barabino, PhD BMES President BMES 2014

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BMES 2014 Meeting Welcome

John A. White, PhD Annual Meeting Chair, BMES 2014 Annual Meeting USTAR Professor of Bioengineering University of Utah

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elcome to the 2014 Annual Meeting of the Biomedical Engineering Society. We are excited to host you, for the first time, in San Antonio, one of the most vibrant and fastest-growing cities in the United States. Our goal is that you learn a great deal, network with your colleagues, and have a great time.

This is the second year that the meeting has been hosted and managed professionally, rather than by a university host. As the meeting has grown in size and impact, the wisdom of this new management model has become increasingly apparent. The logistics and fund-raising have run quite smoothly, mainly due to the efforts of the superb BMES staff, including Meetings Director Debby Tucker, Executive Director Ed Schilling, and Communications Director Doug Beizer. At the heart of our Annual Meeting is the program. We have been extraordinarily fortunate this year to have Dr. Susan Margulies (University of Pennsylvania) as Program Chair. Susan’s dedication to the Society, attention to detail, work

ethic, and interpersonal skills are second to none. We received valuable advice at every stage of program planning from our Senior Advisory Board: Dr. Mauli Agrawal, UTSA; Dr. Peter Katona, George Mason University; Dr. John Linehan, Northwestern University; Dr. Kenneth Lutchen, Boston University; Dr. Rebecca Richards-Kortum, Rice University; and Dr. Paul Yock, Stanford University. I also wish to thank the 2014 Track Chairs. They met a number of challenges and deadlines with promptness, efficiency, and good humor. This year’s meeting has some new twists. To improve the experience and recognition of poster presenters, we have added dedicated morning and afternoon sessions for each poster presenter, as well as session chairs for poster sessions. We have also added poster awards, based on reviewers’ scores. I strongly encourage you attend each of our excellent plenary talks. Let me highlight two fantastic speakers whose identities have already been determined. Our Pritzker Distinguished Lecturer is James Collins of Boston University, a founder of the field of synthetic biology. Our plenary speaker on Friday afternoon is Stephen Oesterle, Senior Vice President for Medicine & Technology at Medtronic, who will share his knowledge about how engineering innovation improves the cost and quality of health care. Finally, take some time to enjoy friendly San Antonio. Our venue is right next to the San Antonio Riverwalk, a cool oasis of restaurants, bars, and shops. The Bash this year will be held at the nearby, unique, and unforgettable Buckhorn Saloon and Museum / Texas Rangers Museum. Enjoy the meeting!

John A. White, PhD

Annual Meeting Chair

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Susan Margulies, PhD Program Chair, BMES 2014 Annual Meeting George H. Stephenson Professor Department of Bioengineering University of Pennsylvania

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elcome to the 2014 BMES meeting! Together with our 42 track chairs who represent a diverse set of BMES members from industry and academia, we have introduced many initiatives this year to enhance the quality of the science presented, value of the meeting to attendees and presenters, and engagement of the BMES membership in the planning and

execution of the meeting. We welcome your feedback on these features. The Chairs of our nineteen traditional tracks overhauled and updated the abstract submission topics, informed by the 86 suggestions submitted by BMES members for state-of-the art and interdisciplinary sessions. We are also grateful for the tireless effort of over 300 BMES members who volunteered to review and/or chair oral and poster sessions, actively partnering with the track chairs, John White and myself to improve and expand BMES 2014. With over 2274 abstracts submitted to the general program, and 385 abstract submitted to the undergraduate research program BMES 2014 is one of our largest meetings to date! This year we have a record-breaking 861 oral presentations in 161 platform sessions, and 1635 posters! To help attendees find the most relevant science at the meeting, the program now includes secondary track designations to guide attendees to related scientific sessions across all of our traditional tracks. Similarly, the posters are now arranged by scientific theme, to allow viewers to locate all the posters on a topic in a single location, regardless of the track. Be sure to consult the color-coded poster session maps in the program to guide your exploration of the posters. To expand the scientific exchange in the poster sessions, posters are now up for the entire day, with two dedicated, unopposed opportunities to talk with the authors. This year, we have introduced poster session chairs who will attend both viewing sessions, and lead walk-about discussions of the posters. To recognize the outstanding science presented in our poster sessions, we have introduced the Reviewer’s Choice awards, awarded to those posters deemed of the highest quality in each track (top 5%) by the reviewers. We encourage you to attend the many special events at the meeting, including plenary lectures, student activities, career development presentations, networking events, informational sessions about federal funding opportunities, cutting edge education technology presentations, featured speakers on our meeting theme, and dedicated special scientific presentation sessions organized by the BMES special interest groups (SIGs). Refer to the Program-at-aGlance to find those events that are of interest to you. John White and I are deeply grateful to the tireless effort of Debby Tucker and Michele Ciapa who work long hours to transform the meeting from a concept to a reality. Ed Schilling the BMES National Meetings Committee, and the BMES leadership have been very supportive of our many new features at this meeting. We extend our sincere appreciation to our Track Chairs who contributed their time, effort, and creativity to design an engaging and inclusive program. Finally, I am especially grateful to John White for his personal and professional partnership on the many programming aspects of BMES 2014. It has been my pleasure and privilege to introduce many innovations this year at BMES 2014 – please stop me at the meeting or contact me with your feedback! Susan Margulies, PhD

Program Chair, BMES 2014 Annual Meeting

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BMES Robert A. Pritzker Distinguished Lecture Pritzker Distinguished Lecturer:

James J. Collins, PhD Howard Hughes Medical Institute Department of Biomedical Engineering & Center of Synthetic Biology, Boston University Wyss Institute for Biologically Inspired Engineering, Harvard University

Thursday, october 23, 2014 10:30am LILA COCKRELL THEATRE, HENRY B. GONZALES CONVENTION CENTER

Life Redesigned: The Emergence of Synthetic Biology

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ynthetic biology is bringing together

James J. Collins is a William F. Warren Distinguished Professor, Uni-

engineers, physicists and biologists to model, design and

versity Professor, Professor of Biomedical Engineering, Professor of

construct biological circuits out of proteins, genes and

Medicine and Director of the Center of Synthetic Biology at Boston

other bits of DNA, and to use these circuits to rewire and

University. He is also a core founding faculty member of the Wyss

reprogram organisms. These re-engineered organisms are going to

Institute for Biologically Inspired Engineering at Harvard University,

change our lives in the coming years, leading to cheaper drugs, rapid

and an Investigator of the Howard Hughes Medical Institute. His

diagnostic tests, and targeted therapies to attack "superbugs". In this

research group works in synthetic biology and systems biology, with

talk, we highlight recent efforts to create synthetic gene networks

a particular focus on using network biology approaches to study an-

and programmable cells, and discuss a variety of synthetic biology

tibiotic action, bacterial defense mechanisms, and the emergence of

applications in biocomputing, biotechnology and biomedicine.

resistance. Professor Collins' patented technologies have been licensed by over 25 biotech, pharma and medical devices companies, and he has helped to launch a number of companies, including Sample6 Technologies, Synlogic and EnBiotix. He has received numerous awards and honors, including a Rhodes Scholarship, a MacArthur "Genius" Award, an NIH Director's Pioneer Award, a Sanofi-Institut Pasteur Award, as well as several teaching awards. Professor Collins is an elected member of the National Academy of Sciences, the National Academy of Engineering, the Institute of Medicine, and the American Academy of Arts & Sciences, and a charter fellow of the National Academy of Inventors.

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special plenary session | thursday

BMES Special Interest Group: Medical Devices – Computational Modeling and Simulation for Medical Devices thursday october 23, 2014 6:15PM - 7:30PM LILA COCKRELL THEATRE HENRY B. GONZALES

Computer Modeling and Simulation for Medical Devices

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he BMES Medical Device Special Interest

Session Chair:

Group was formed in 2014 as a forum for medical

Walt Baxter, Medtronic Co-Chair, BMES-FDA

device biomedical engineering interests. The initial

Frontiers in Medical Devices Conference

focus, Computational Modeling and Simulation for

Medical Devices, brings together people from the medical device and simulation software industries and academic, clinical and other researchers to share scientific findings. Today, there are limited models that are shared publically therefore limited common understanding of simulation results and discussion of their interpretation. We

SPEAKERS:

Modeling and Simulation for Medical Devices: An FDA Perspective Donna Lochner, FDA Co-Chair, BMES-FDA

aim to provide a symposium for modeling and simulation for medical

Frontiers in Medical Devices Conference

devices to promote best methods, identify credible boundary and encourage future discovery. We focus on applications of modeling

Translation of Modeling & Simulation Tools from Research to R&D/Clinical Applications

and simulation that advance the design, evaluation and production of

Anthony Petrella, Colorado School of Mines

system conditions, share interpretation of simulation results, and

medical devices. This Special Session at the BMES Annual Meeting will introduce the Medical Devices SIG and explore how modeling and simulation can play a role in: • ensuring the safety and effectiveness of medical devices, • speeding the translation of academic models to clinical application, • improving the regulatory evaluation process providing credible methods to evaluate medical devices.

Use of Computational Modeling in the Development of Aortic Stent Grafts and Early Clinical Feasibility Studies Ben Wolf, Medtronic, Endovascular Therapies

Ensuring Models and Simulations are Credibility for Regulatory Decision Making Tina Morrison, FDA

sponsored by

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NIH NIBIB Lecture

NIH National Institute of Biomedical Imaging and Bioengineering Lecture:

David Kaplan, PhD Stern Family Professor of Engineering Professor and Chair, Department of Biomedical Engineering Professor, Department of Chemical Engineering Director, Bioengineering and Biotechnology Center, Tufts University

Friday, october 24, 2014 10:30AM LILA COCKRELL THEATRE HENRY B. GONZALES CONVENTION CENTER

Silk Biomaterials – The New Silk Road

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he field of biomaterials and tissue

David Kaplan is a biomedical engineer who has studied biomateri-

engineering has emerged in terms of scientif-

als for his entire career. His group focuses on biopolymers and their

ic and translational impact over the past few decades

engineering for new biomaterials, covering fundamental questions

by embracing intersections between engineering,

to translational goals. He is the inaugural endowed Stern Professor

materials science, biology and medicine. We have focused our ef-

of Engineering and has been chair of the Department of Biomedical

forts on biopolymer engineering to understand structure-function re-

Engineering since its founding in 2002. His B.S. was from SUNY Al-

lationships, with studies on self-assembly, biomaterials engineering,

bany and his PhD from SUNY Syracuse and Syracuse University. His

tissue engineering and regenerative medicine. Structural proteins,

group has published over 600 peer reviewed papers, and generated

including collagens, elastins, resilins and silks have been our focus,

more than 50 patents that have led to seven startup companies and

with a particular emphasis on the study of silk-based biomaterials in

new FDA approved medical devices.

regenerative medicine, from fundamental studies of the biochemistry, molecular biology and biophysical features of these fibrous proteins to their impact on stem cell functions and complex tissue formation. Tissue engineering and regenerative medicine emerge though control of biomaterials structure-function relationships and 3D tissue co-culture systems to establish and study human tissues in the laboratory and in animal systems.

He has directed the NIH P41 Tissue Engineering Resource Center (TERC) since 2004, a program involving Tufts University and Columbia University. He serves on the editorial boards of numerous journals and is the inaugural Editor in Chief of ACS Biomaterials Science and Engineering. He has received a number of awards for teaching, was Elected Fellow of the American Institute of Medical and Biological Engineering, received the Columbus Discovery Medal and the Society for Biomaterials Clemson Award for contributions to the literature. Professor Kaplan also holds faculty appointments in the School of Medicine, the School of Dental Medicine, the Department of Chemistry and the Department of Chemical and Biological Engineering at Tufts University. He also has a university professor appointment at Soochow University in China and fosters joint research between institutions. He has an extensive network of collaborators around the world that providing complementary expertise and opportunities for synergistic studies and student exchanges.

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Special plenary session | friday

Stephen Oesterle, MD Senior Vice President for Medicine & Technology Medtronic

Friday, october 24, 2014 5:15PM - 6:15PM LILA COCKRELL THEATRE HENRY B. GONZALES CONVENTION CENTER

Converging Low Power Microelectronics, IT and Communication Technologies into Implantable Medical Devices

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edtronic is one of the world¹s

Stephen N. Oesterle, MD joined the company in 2002 as Senior

largest medical device companies. With more

Vice President for Medicine and Technology. In this role, Steve pro-

than 50,000 employees, it operates in 140 coun-

vides executive leadership for Medtronic scientific research, forma-

tries, delivering medical products to more than

tion of technological strategies and continued development of strong

10 million people each year. Medtronic must continue to innovate

cooperative relationships with the world's medicinal communities,

while delivering effective products for less cost. The challenge of

technical universities, financial institutions and emerging medical de-

developing medical devices for the more than 4 billion people who

vice companies.

today have no access to care is immediate. The incorporation of low power and flexible microelectronics into implantable medical devices has substantially broadened applications for these devices while allowing for less invasive delivery and reduced complications. Cardiac pacemakers have been reduced in dimension by magnitudes; the potential to deliver a wafer scale pacemaker will soon be realized. Implantable and wearable physiologic sensors will facilitate remote management of the devices and the patients who use them. Conver-

Previously, Steve served as Associate Professor of Medicine at the Harvard University Medical School and as Director of Invasive Cardiology Services at Massachusetts General Hospital, Boston. A teacher and innovator in the field of cardiac catheterization, he has also developed and directed interventional cardiology programs at Good Samaritan Hospital, Los Angeles; at Georgetown University; and at Stanford University.

gence of information and communication technologies into medical

Steve is a 1973 summa cum laude graduate of Harvard College and

devices will catalyze Medtronic’s vision to distribute health care to bil-

received his doctorate from Yale University in 1977. He completed

lions of patients who have minimal access to affordable care. Chron-

his internship and residency at Massachusetts General Hospital and

ic diseases such as heart failure, diabetes and hypertension can be

also served a fellowship in interventional cardiology at Stanford.

better managed with implanted and wearable microelectronics and adaptive closed loop algorithms. It all starts and ends with engineers.

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Rita Schaffer Memorial Lecture BMES 2014 Rita Schaffer Memorial - Young Investigator Lecturer:

Kimberly M. Stroka, PhD Postdoctoral Fellow in the Konstantopoulos Lab Johns Hopkins University

Saturday, october 25, 2014 10:30am LILA COCKRELL THEATRE HENRY B. GONZALES CONVENTION CENTER

New Paradigms for Cell Migration in Confined Microenvironments

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ell homeostasis and diverse process-

Kimberly M. Stroka is a postdoctoral fellow at Johns Hop-

es, including migration, are tightly regulated by cell

kins University in the Department of Chemical and Biomolecular En-

volume. In vivo, metastatic tumor cells must navigate

gineering and Institute for NanoBioTechnology. In January 2015 she

complex, heterogeneous microenvironments when

will begin her appointment as Assistant Professor at the University of

migrating through tissues, including longitudinal tracks formed by

Maryland, College Park in the Fischell Department of Bioengineering.

anatomic structures. Intriguingly, we have discovered that the clas-

Dr. Stroka received her B.S. summa cum laude in Physics in 2006

sical model of cell migration on two-dimensional substrates (relying

from Denison University. She received her Ph.D. in Bioengineering

on actin polymerization, cell adhesion to the substrate, and myosin

in 2011 from the University of Maryland-College Park while working

II-mediated contractility) does not apply to metastatic tumor cells

with Helim Aranda-Espinoza. In her PhD work, Dr. Stroka developed

migrating through three-dimensional confined spaces. We therefore

a novel hydrogel-based in vitro model in order to evaluate the effects

hypothesized that an alternate mechanism based on cell volume

of blood vessel stiffening on endothelial cell biomechanics, leukocyte

regulation via ion channels and aquaporins drives cell migration in

mechanosensing, and leukocyte transmigration, during a normal im-

these confined microenvironments, where cells must deform in or-

mune response and in the context of cardiovascular disease. In Dr.

der to squeeze through physically restrictive spaces. Using a mul-

Stroka's postdoctoral work in the lab of Konstantinos Konstantopou-

tidisciplinary approach that integrates microfabrication techniques,

los, she has integrated microfabrication, molecular biology, live cell

molecular biology, live cell imaging, and theoretical modeling based

imaging, and theoretical modeling in order to uncover a new mecha-

on physics, we have discovered an "Osmotic Engine Model" of cell

nism by which metastatic tumor cells migrate through confined mi-

migration, which demonstrates that osmotically-driven water flow

croenvironments. This work was recently published in Cell.

regulates cell migration in confined microenvironments. Importantly, our theoretical model predicts many key non-intuitive experimental results. Collectively, this study represents a new paradigm for cell migration in confined microenvironments and elucidates ion pumps and aquaporins as new molecular targets that may be exploited for future development of cancer therapeutics.

Dr. Stroka's postdoctoral and predoctoral work has been supported by numerous highly competitive fellowships, including an NIH NRSA F32 postdoctoral fellowship (2013-present), NIH T32 postdoctoral fellowship (2012-2013), NIH NRSA F31 predoctoral fellowship (20102011), and NSF Graduate Research Fellowship (2006-2009). Dr. Stroka was also recently awarded the Burroughs Wellcome Career Award at the Scientific Interface (2014-2019) for her proposal on engineering

BMES established this award in 2000 to honor Rita M. Schaffer, former BMES Executive Director. Rita’s gift of her estate, along with contributions from her family, friends, and associates, has enabled BMES to create the Rita Schaffer Young Investigator Award, which includes the Rita Schaffer Memorial Lecture.

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blood-brain barrier mechanobiology in the context of tumor cell metastasis. She is the recipient of 9 different awards for travel to national and international conferences (2008-2011).

BMES Diversity Award Lecture Diversity Lecture:

Naomi Chesler, PhD Vice Chair of Biomedical Engineering University of Wisconsin-Madison

Saturday, october 25, 2014 11:15am LILA COCKRELL THEATRE HENRY B. GONZALES CONVENTION CENTER

The Power of Privilege – Using Our Strengths to Overcome Our Weaknesses in Diversity and Inclusivity

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he current pool of biomedical engineers is not diverse enough to solve the complex health and medical technology problems facing our society today.  In the undergraduate experience, being part of a diverse classroom and community leads to increased student engagement in learning and greater gains in critical thinking, problem solving and self-confidence.  Also, motivation to consider multiple perspectives, which is an important skill in teamwork, increases with diversity, as does productivity and innovation. Therefore, increasing the diversity of our discipline will have concrete and significant benefits for the current and future biomedical engineering workforce.

Mechanical Engineering from MIT and a PhD in Medical En-

Often, the most visible and vocal proponents of increased

findings in this area regularly in biomedical and mechanical

diversity and inclusivity are members of under-represented

engineering journals as well as physiology journals and is a

groups. While biomedical engineering has a higher percent-

recipient of the NSF CAREER Award and funding from the

age of women than almost any other engineering discipline,

Whitaker Foundation, the American Heart Association and

most senior leaders in biomedical engineering both in in-

the NIH both independently and collaboratively. 

dustry and academia are members of the majority.  Thus, in order to improve and enhance the diversity and inclusivity of our discipline, I propose we use these strengths – our many majority members -- and their privilege.  In particular, I challenge our community to use the power of privilege to promote inclusive excellence and thereby improve critical thinking and problem-solving, teamwork and innovation in biomedical engineering.

gineering from the Harvard-MIT joint program in Health Sciences and Technology.  Dr. Chesler’s biomechanics research seeks to improve cardiovascular health through the integration of mechanical engineering, vascular biology and imaging tools, to advance knowledge in these fields, and to educate the next generation of leaders in cardiovascular engineering and science.  In particular, her lab (vtb.bme.wisc.edu) strives to better understand and prevent ventricular failure by focusing on three aspects of physiology and pathophysiology: ventricular function, blood flow dynamics, and changes in the large and small artery structure and function.  She publishes her

Dr. Chesler also investigates mentoring and curricular change strategies for improving the recruitment and retention of women and underrepresented minorities in engineering.  Her scholarly contributions in this area have been published in the Journal of Engineering Education, Journal of Women and Minorities in Science and Engineering, Advances in Engineering Education and also the BMES flagship journal Annals of Biomedical Engineering. She is an integral

Naomi C. Chesler is Professor and Vice Chair

part of the Epistemic Games Group at UW-Madison (edgaps.

of Biomedical Engineering at the University of Wisconsin-

org), which is funded by the NSF to design and implement

Madison. Her research accomplishments are in the areas

engineering epistemic games for first-year curricula with in-

of cardiovascular biomechanics and engineering education.

tegrated mentoring and assessment. 

Her broad contributions to the physical, biological and social sciences have been recognized by courtesy appointments in the Departments of Mechanical Engineering, Medicine, Pediatrics and Educational Psychology at UW-Madison.  One key foundation for this wide-ranging impact was her liberal arts education from Swarthmore College, where she earned a BS in engineering (general). She then obtained an MS in

She is a Fulbright Scholar, fellow of the American Society of Mechanical Engineers and prior recipient of the Denice D. Denton Emerging Leader Award from the Anita Borg Institute for Women and Computing. She was recently named a Vilas Distinguished Achievement Professor at UW-Madison and is honored to receive the BMES Diversity Award. BMES 2014

13

Frontiers in Medical Devices Conference Innovations in Modeling and Simulation Using Modeling and Simulation at Different Stages in the Total Product Life Cycle May 18-20, 2015 Washington DC The College Park Marriott Hotel and Conference Center at the University of Maryland

The Biomedical Engineering Society and the US Food and Drug Administration have formed a partnership to co-host the BMES/ FDA Frontiers in Medical Devices Conference, a meeting for researchers, engineers, clinicians and other professionals in the fields of designing, building and using medical devices.

A Call for Abstracts is Open! Papers, presentations and posters highlighting the meeting’s theme “Using Modeling and Simulation at Different Stages in the Total Product Life Cycle” are being sought.

www.bmes.org/meddevicesabstracts

Keynote Speakers Dr. Marco Viceconti, Executive Director of the INSIGNEO institute for in silico medicine and Chair of Biomechanics in the Department of Mechanical Engineering at the University of Sheffield. Dr. Scott Hollister, Professor of Biomedical Engineering and Mechanical Engineering and Associate Professor of Surgery at the University of Michigan.

Conference Tracks Model Foundations for Device Design Ideation Neils Kuster, IT’IS Foundation Concept Development and Design Optimization Art Erdman, University of Minnesota Modeling for Robust Design Thor Bezier, University of Auckland Design Verification and Validation Anita Bestelmeyer, Becton, Dickinson and Company Patient Specific Design Matthew Debeule, FEops Discussion Panel: How Good is Good Enough? Tina Morrison, US Food and Drug Administration Integration of Modeling with Clinical Studies Tarek Haddad, Medtronic, Inc. Modeling and Device Commercialization Charley Taylor, HeartFlow Please visit www.bmes.org/meddevicessig for additional information about the meeting.

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BMES 2011

BMES 2014

17

Visit the

Booth at BMES!

Visit Booth #116 and get your FREE 2014 meeting essentials like luggage tags, pens, and more! Discover how you can get involved with the APS’ award-winning programs and services, including career resources, extensive awards programs, exciting education programs, diverse membership, exceptional scientific meetings, prestigious publications, and innovative advocacy resources. www.the-aps.org

careers meetings

education

awards

membership publications

AWARDS—400+ awards valued at $1,200,000 • Society & section awards • Teaching & student awards

• Fellowships & grants

science policy

EDUCATION—Check out the new Life Science Teaching Resource Community • Benefit from K-12, undergraduate, graduate/professional, & continuing education programs • Use free teaching & learning resources • Participate in the professional skills training courses • Engage in the diversity programs MEETINGS—Join us for the 2015 Meetings and Conferences • Plan for Experimental Biology 2015, March 28-April 1 in Boston, Massachusetts • Attend the 2015 APS Conference: 14th International Conference on Endothelin: Pathophysiology and Therapeutics, September 2-5, 2015 in Savannah, Georgia • Sponsor a meeting

store

MEMBERSHIP—Undergraduate student membership is $10 and Graduate membership is $15 • Receive free essential color figures • Jump start or develop your career & join the APS • Gain access to all APS journals • Get discounted meeting registration online & Legacy Content • Serve on sections and committees • Join specialized listservs and chapters PUBLICATIONS—NEW APSselect article collection website • APSselect offers a monthly collection of the “best of the best” original research articles from the APS journals http://apsselect.physiology.org • View our 15 highly cited, peer-reviewed journals including the new Physiological Reports open-access, online-only journal • Use the APS Legacy Content & Journals Digital Library at www.physiology.org • Submit your manuscripts—reviewed quickly and published online within days of acceptance • Sign up for free eTOCs, CiteTrack, RSS Feeds, and Podcasts • Read The Physiologist and eNews Update to stay abreast of physiology and society affairs SCIENCE POLICY—Online Advocacy Resources Your voice in Washington on • Research funding • Animal research issues • Follow on Twitter at twitter.com/SciPolAPS or @SciPolAPS

the-aps.org/store

the-aps.org

® The APS logo is a trademark of the American Physiological Society.

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Exhibits

Exhibits

Booth # 634

AIP Publishing 1305 Walt Whitman Road, Suite 300 Melville, NY 11747 Phone: 516-576-2279 Email: [email protected] Web: www.journals.aip.org AIP Publishing is a scholarly publisher in the physical and related sciences that provides a comprehensive collection of highly cited peer reviewed journals.  AIP Publishing’s portfolio of 17 journals includes prestigious titles such as Applied Physics Letters, Journal of Applied Physics and The Journal of Chemical Physics.  http://journals.aip.org Booth # 116

American Physiological Society 9650 Rockville Pike Bethesda, MD 20814 Phone: 301-634-7246 Email: [email protected] Web: www.the-aps.org The American Physiological Society (APS) is a nonprofit devoted to fostering education, scientific research, and dissemination of information in the physiological sciences. The Society was founded in 1887 with 28

members and now has over 10,500 members worldwide. Discover how you can benefit from the APS award-winning programs and services, including career resources, extensive awards programs, exciting education programs, diverse membership, exceptional scientific meetings, prestigious publications, and innovative advocacy resources. Booths # 415/417

Arizona State University School of Biological and Health Systems Engineering P.O. Box 879709 Tempe, AZ 85287-9709 Phone: 480-965-3028 Email: [email protected] Web: engineering.asu.edu/sbhse The mission of the School of Biological and Health Systems Engineering at ASU is to create novel solutions to improve human health through research, education, and service to the community. The faculty in SBHSE has a wide range of research expertise with strengths in the following research areas: imaging, biosensors and instrumentation, molecular, cellular and tissue engineering, neural and rehabilitation engineering, synthetic biology and systems bioengineering. Booth # 517

Binghamton University Department of Bioengineering 4400 Vestal Parkway East Binghamton, NY 13902 Phone: 607-777-5238 Email: [email protected] Web: www.binghamton.edu/bioengineering/grad The Binghamton University Department of Bioengineering provides a state-of-the-art, affordable education. We train the next generation of biomedical engineers, cultivate leaders, and foster entrepreneurship  through the integration of engineering principles, the physical sciences, and biology towards better disease prevention, diagnostics, treatment, and health care systems. Booth # 500

Biomomentum Inc. 970 Michelin Street, Suite 200 Laval, Quebec H7L 5C1 Canada Phone: 450-667-2299 Email: [email protected] Web: www.biomomentum.com Biomomentum commercializes the Mach-1™, a configurable mechanical tester capable of performing compression, tension, shear, and torsion for precise characterization of cartilage and soft materials. The Mach-1™ is the only tester that can automatically map the mechanical properties of an entire sample’s surface in 3D. Biomomentum also offers biomechanical testing services.

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BMES 2014

Exhibits Exhibits Booth # 527

Booth # 334

BIOPAC Systems, Inc.

Cambridge University Press

42 Aero Camino Goleta, CA 93117 Phone: 805-685-0066 Email: [email protected] Web: www.biopac.com

32 Avenue of the Americas New York, NY 10013 Phone: 212-924-3900 Email: [email protected]rg Web: www.cambridge.org/us/academic

Complete data acquisition and analysis solutions for biomedical engineering applications. BIOPAC is trusted by thousands of labs and cited in over 18,000 scientific articles. Wireless and wearable solutions: Mobita 32CH, BioNomadix ECG, EEG, EMG, EOG, NICO, GSR, Pulse, Resp., and more! Powerful AcqKnowledge software has automated analysis and customizable display.

Visit the Cambridge University Press booth to save 20% on books including: Willams’ Essential Biomaterials Science, Agrawal et al.’s Introduction to Biomaterials, Biomaterials and Regenerative Medicine edited by Ma, Saltzman’s Biomedical Engineering, Yock et al.’s Biodesign 2nd Edition. If you have book ideas, please speak with editor Dr. Michelle Carey. Booth # 436

Booth # 529

Boston University Biomedical Engineering 44 Cummington Mall Boston, MA 02215 Phone: 617-353-2805 Email: [email protected] Web: www.bu.edu/bme The Boston University Department of Biomedical Engineering is one of the largest and oldest departments of its kind in the country. We attract exceptional students to our BS, MEng, MS and PhD degree programs, which are known for their highly quantitative approach. We have strengths in numerous research areas including biomechanics, neural engineering, biomedical optics, respiratory dynamics, tissue engineering, biomaterials and synthetic biology. We boast a wealth of research resources, and have strong ties with the BU School of Medicine, and other top medical research centers in the Boston area. Booth # 228

Brown University Center for Biomedical Engineering 171 Meeting Street Providence, RI 02912 Phone: 401-863-6778 Email: [email protected] Web: www.brown.edu/bme The Center for Biomedical Engineering at Brown University features an interdisciplinary approach in four complementary research areas: Neuroengineering, biosensors/bioplatforms, mechanobiology, and tissue engineering/regenerative medicine. The program offers BS, MS, and PhD degrees and is distinguished by its research and strong collaborative connections between academic science/engineering, clinical medicine, and industry.

Carnegie Mellon University 5000 Forbes Avenue Pittsburgh, PA 15213 Phone: 412-268-6222 Email: [email protected] Web: www.bme.cmu.edu The Department of Biomedical Engineering at Carnegie Mellon is built upon a long tradition of interdisciplinary research across departmental borders. Its decades-old research program emphasizes a collaborative network that balances four synergistic areas: basic engineering principles of living cells and tissues, engineering tools for biomedical research, interface between living and artificial materials, and clinical applications of biomedical engineering. Training programs encourage students to expand their vision and prepare them for a wide range of careers from academic research in basic sciences, to engineering entrepreneurship, to medical care. Booth # 300

Case Western Reserve University Department of Biomedical Engineering 309 Wickenden Building 10900 Euclid Avenue Cleveland, OH 44106-7207 Phone: 216-368-4094 Email: [email protected] Web: http://bme.case.edu/ The Department of Biomedical Engineering at Case Western Reserve University offers distinctive programs ranging from the B. S. degree through the Ph.D. degree, including our innovative M.D./Ph.D. degree, M. D./M.S. degree, and our Biomedical Entrepreneurship program.   Cutting-edge research thrusts include:  biomaterials and tissue engineering, neural engineering and neuroprostheses, biomedical imaging and sensing, transport and metabolic engineering, biomechanics, and targeted therapeutics. Booth #611

CD-adapco 60 Broad Hollow Road Melville, NY 11747 Phone: 671-629-3132 Email: [email protected] Web: www.cd-adapco.com

exHIBITS

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exhibits Exhibits

Booth # 405

booths # 502 / 504

CellScale Biomaterials Testing

Columbia University

3B- 572 Weber Street N. Waterloo, Ontario N2L 5C6 Canada Phone: 519-342-6870 Email: [email protected] Web: www.cellscale.com

Department of Biomedical Engineering 351 Engineering Terrace 1210 Amsterdam Avenue New York, NY 10025 Phone: 212-854-6196 Email: [email protected] Web: www.bme.columbia.edu

CellScale manufactures biomaterial and mechanobiology test systems. Our mechanical test systems are specifically designed for biomaterials testing and incorporate temperature-controlled media baths, image capture and analysis software, and a range of gripping mechanisms. Our cell culture systems enable mechanically active environments in 2D or 3D. Booth # 501

Cincinnati Sub-Zero 12011 Mosteller Road Cincinnati, OH 45241 Phone: 513-772-8810 Email: [email protected] Web: www.cszmedical.com Cincinnati Sub-Zero has been delivering patient temperature management systems since 1963. Our complete line of products includes therapeutic heating/cooling therapy units and warming/cooling blankets. Booth # 329

The City College of New York Biomedical Engineering 160 Convent Avenue, T401 New York, NY 10031 Phone: 212-650-6707 Email: [email protected] Web: bme.ccny.cuny.edu The City College of New York – the founding college of CUNY. Founded in 1847, it has produced nine Nobel Prize winners and ranks seventh in the number of alumni who have been elected to the National Academy of Sciences. The Biomedical Engineering Department was established in 2002. BME at CCNY: Biomaterials/nanotechnology; Cardiovascular Engineering; Musculoskeletal Biomechanics; and Neural Engineering. Booth # 237

Clemson University Department of Bioengineering 301 Rhodes Research Center Clemson, SC 29634-0905 Phone: 864-656-7276 Email: [email protected] Web: www.clemson.edu/ces/bioe Adding 30,000 sqft of research labs and innovation space for business partnership, our newest facility is CUBEInC, Clemson University Biomedical Engineering Innovation Campus, where student-faculty-clinician teams develop and test emerging technologies. Our continuing commitment to excellence in undergraduate and graduate education assures degree market value and stimulates economic development. exHIBITS

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The Department of Biomedical Engineering at Columbia University offers biomedical engineering education and research through undergraduate B.S. to Ph.D. and M.D./Ph.D. degree programs. Our department provides a surprising mix of the intellectual atmosphere of an Ivy League institution and the sense of community of a small college enriched by the diversity of New York City. Booths # 401 / 403

Cornell University Department of Biomedical Engineering 101 Weill Hall Ithaca, NY 14853 Phone: 607-255-2573 Email: [email protected] Web: www.bme.cornell.edu Biomedical Engineering at Cornell University focuses on interdisciplinary research to achieve a quantitative understanding of human biology at all spatial and temporal scales with the goal of improving human health. The Department has a close relationship with Weill Cornell Medical College and its associated hospitals in New York City, including an “Immersion Term” during which all Ph.D. students spend 7 weeks in a clinical experience at the Medical College. Cornell University is a comprehensive university with outstanding programs of teaching and research in all areas of human inquiry which has its main campus at Ithaca in the Finger Lakes Region of upstate New York. A new Engineering campus is opening in New York City located on a site less than 20 minutes from the Medical College which will catalyze further growth in the Department’s interactions with the Medical College and hospitals. The Biomedical Engineering Department has close collaborations with a wide variety of other departments in Ithaca, especially with those in the Colleges of Engineering, Veterinary Medicine, Agriculture and Life Sciences, Arts and Sciences, and Human Ecology Booth # 133

Covidien 15 Hampshire Street Mansfield, MA 02048 Phone: 508-261-8000 Web: www.covidien.com Covidien is a $10 billion global healthcare products leader dedicated to innovation and long-term growth. We create innovative medical solutions for better patient outcomes and deliver value through clinical leadership and excellence.  Please come visit a few of our team members at Booth #133 to see hands-on examples of some of our energy-based surgical products, learn about our other product families, obtain information on joining our team via internships and full-time careers, and much more.

exhibits

Booth # 121

Booth # 603

CRC Press

Duquesne University

6000 Broken Sound Parkway NW Suite 300 Boca Raton, FL 33487 Phone: 561-361-6000 Email: [email protected] Web: www.crcpress.com

Biomedical Engineering 600 Forbes Avenue 307 Libermann Hall Pittsburgh, PA 15212 Phone: 412-396-2661 Email: [email protected] Web: www.duq.edu/bme

CRC Press - Taylor & Francis is a premier publisher in biomedical engineering textbooks, professional manuals, reference works, journals, and electronic databases. Please visit our booth to peruse our titles, receive special convention discounts, and pick up copies of our journals. Talk to us about being a CRC Press Author!

NEW

FOR FALL 2015!

We will be promoting the new Biomedical Engineering Program at Duquesne University.  We will also introduce the BME/BSN program, a five year curriculum that results in bachelor’s degrees in engineering and nursing, providing the graduate with technical knowledge and clinical experience.  

Joint Undergraduate Program in

BIOMEDICAL ENGINEERING

AND

NURSING

(BME-BSN)

Duquesne University’s Biomedical Engineering Program and School of Nursing will launch a program that combines the sought-after credentials of bachelor of science degrees in both biomedical engineering (BME) and nursing (BSN), becoming the first academic institution in the U.S. and globally to offer this dual degree to undergraduates.

Learn more by visiting www.duq.edu/bme-bsn Connect with us

I [email protected] I 412.396.6222 exHIBITS

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Launch Your Technical Leadership Career

Full-time engineering development program for high-caliber new grads Ready for an innovative and meaningful career? Interested in applying your talents to solve complex challenges that will save lives? Then there’s never been a better time to join Edwards Lifesciences, the global leader in the science of heart valves and hemodynamic monitoring. You’ll thrive in our formal engineering development program, which combines a summer networking and educational program with ongoing personal mentorship, technical peer support, and senior management collaboration and guidance. It’s the ideal foundation for launching your career. Find out more about our Internships and New Grad Programs at Edwards.com/University A number of engineering backgrounds are welcome, including biomedical, mechanical, chemical, electrical, packaging, industrial, materials, manufacturing, quality and engineering management. You should be on track to earn a B.S. or M.S. in engineering as well as have a 3.0 GPA and proof of U.S. citizenship or permanent residency authorization.

Edwards Lifesciences, and the stylized E logo are trademarks or service marks of Edwards Lifesciences Corporation.© 2014 Edwards Lifesciences Coporation. All rights reserved.

Edwards Lifesciences USA | Switzerland | Japan | China | India | Australia | Brazil edwards.com

Engineering New Grad Programs We offer program participants two unique technical engineering tracks in our Irvine, California and Draper, Utah locations. Technical Development Program This 18-month, full-time, broad-spectrum rotational program offers four handson work rotations that deliver multi-product exposure across all businesses and functions. University Engineering Program Gain a highly-focused specialization in one of four business units: Cardiac Surgery Systems, Critical Care, Heart Valve Therapy, or Transcatheter Heart Valves.

Exhibits

Booth # 311

Booth # 516

Edwards Lifesciences

Engineering World Health

One Edwards Way Irvine, CA 92614 Phone: 949-756-4258 Email: [email protected] Web: www.edwards.com

The Prizery, Suite 200 302 East Pettigrew Street Durham, NC 27701 Phone: 919-682-7788 Email: [email protected] Web: www.ewh.org

Edwards Lifesciences is the global leader in the science of heart valves and hemodynamic monitoring. Driven by a passion to help patients, the company partners with clinicians to develop innovative technologies in the areas of structural heart disease and critical care monitoring that save and enhance lives.

BIOCERAMICS:

ADVANCES & CHALLENGES FOR AFFORDABLE HEALTHCARE PRESENTED BY DR. LARRY HENCH Part of a new series offered in association with The American Ceramic Society, tailored to working professionals in the engineering and healthcare elds with an interest in bioceramics. http:///t.edu/biomedical-professional

Engineering World Health is an NGO that works with the BME community to improve healthcare delivery in developing world hospitals. We build local capacity to manage and maintain medical equipment, make repairs, and develop low-cost technologies. Visit our booth to learn about making a lasting impact on developing world health care!

Department of Bioengineering

Solving problems that matter PhD D in Bioengineering

Starts January 2015 AREAS OF STUDY:

Biomedical imaging Data-driven biomechanical modeling Nanoscale bioengineering Neuroengineering To apply contact: [email protected] 703.993.1512 Dept. of Bioengineering [email protected] 703.993.4190

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Exhibits

Booth # 304

Booth # 514

EnvisionTEC

FASEB

15162 S. Commerce Drive Dearborn, MI 48120 Phone: 313-436-4300 Email: [email protected] Web: http://www.envisiontec.com

9650 Rockville Pike Bethesda, MD 20814 Phone: 301-634-7930 Email: [email protected] Web: www.faseb.org/marc

EnvisionTEC has been selling the 3D-Bioplotter® for over 12 years. The 3D-Bioplotter® was developed for the 3D printing of biomaterials, includ ing cells, and is not only an excellent research tool, but also a manufacturing tool with high accuracy and reproducibility. It is open to allow the usage of any customer chosen material, including cells, making it ideal for material scientists in research and industry alike. It is available in a Developer Series, aimed at academia, and a Manufacturer Series, aimed at industry and advanced research. EnvisionTEC has close to 12 years experience in the field of Tissue Engineering with this system having been used in numerous in vitro and in vivo experiments, resulting in close to one hundred scientific publications. The 3D-Bioplotter® has found a home in universities, research centers, and hospitals the world over where leading researchers in a wide variety of fields are working towards bioprinting solutions.

FASEB MARC (Maximizing Access to Research Careers) Program provides a variety of activities to support the training of students, postdoctorates, faculty and researchers from underrepresented groups who are engaged in the biomedical and behavioral sciences research and training.

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We offer faculty/mentor with students and poster/platform presenter travel awards for scientific meetings (National and regional) and FASEB Science Research Conferences. We also sponsor career/leadership development and grantsmanship training seminars and workshops.

Exhibits

Booth # 608

Booth # 423

Florida Institute of Technology

George Washington University

150 W. University Blvd. Melbourne, FL 32901 Phone: 321-674-8382 Email: [email protected] Web: www.fit.edu/continuing-edu

School of Engineering & Applied Sciences 801 – 22nd Street, NW, Room 608 Washington, DC 20052 Phone: 202-994-5934 Email: [email protected] Web: http://www.seas.gwu.edu/bme

Florida Tech presents its cutting-edge online certificate program in Biomedical Engineering. Overseen by esteemed BME scientist Larry Hench, our program provides a comprehensive educational background for undergraduate, master’s, and doctoral-level learners. Course content includes: biomaterials, devices, tissue engineering, socio-economic issues, best practices, and the ethics of reconstructive and regenerative medicine. Booth # 233

Florida International University Biomedical Engineering Department 10555 West Flagler Street EC 2610 Miami, FL 33174 Phone: 305-348-1409 Email: [email protected] Web: www.bme.fiu.edu The Coulter Foundation endowed Department of Biomedical Engineering at Florida International University in Miami is the only program with doctoral, masters and accredited bachelors among all of the public universities in the State of Florida and amongst the Hispanic and Minority serving universities in the nation. Multiple undergraduate and graduate scholarships support research and entrepreneurship. Senior Design projects are extensively industry sponsored and the MS professional track includes courses in management. New faculty hires, revised doctoral curriculum and extensive links with the Colleges of Medicine, Nursing & Health Sciences and Arts & Sciences allow research focus in Engineered Tissue Model Systems, Diagnostic Bioimaging and Sensor Systems, and Therapeutic and Reparative Neurotechnology. Booth # 609

George Mason University Department of Bioengineering 4400 University Drive Fairfax,VA 22030 Phone: 703-993-5769 Email: [email protected] Web: http://bioengineering.gmu.edu Located in the Washington DC metropolitan area, George Mason University’s Department of Bioengineering offers unique research and educational experience with collaborative opportunities with nearby national laboratories, institutes, and clinical facilities. The BS program earned accreditation from ABET in 2012 offers two concentrations: Biomedical Signals & Systems and Bioengineering Healthcare Informatics. The Bioengineering PhD program will begin in January 2015 and is currently accepting applications from outstanding prospective students. The department has 12 primary faculty members with $6.4M of active research in areas ranging from biomedical imaging, nanotechnology, neural engineering, and data-driven biomechanics.

The graduate program in biomedical engineering at the George Washington University offers a unique combination of small class sizes, engaged faculty, and cutting edge research.  Areas of research include medical imaging instrumentation, therapeutic ultrasound, image analysis, microfluidics, biosensors, and electrophysiology.  The Department of Biomedical Engineering offers both M.S. and Ph.D. degrees in Biomedical Engineering.  Our new Science and Enginering Hall will open winter 2014 directly across the street from the GW School of Medicine and Health Sciences which gives our faculty and students direct access to real world medical problems.  In addition, our location in the heart of the nation’s capital affords our students and faculty unparalleled access to world class research facilities in a number of government laboratories including the National Institutes of Health and the Food and Drug Administration. Booth # 409

The Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech / Emory University & Peking University 313 Ferst Drive Atlanta, GA 30332-0535 Phone: 404-385-0124 Email: [email protected] Web: www.bme.gatech.edu The Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University is inventing the future of healthcare, with breakthrough research in Pediatric Bioengineering, Immunoengineering, Neuroengineering and Cardiovascular engineering.  Our programs are consistently ranked among the highest in the nation. BME at Georgia Tech and Emory University is home to five NIH training grants and innovative initiatives that build entrepreneurial confidence in our students.  Unique to Georgia Tech and Emory is the BioID Master’s program, which focuses on real world training in product development and clinical experience to transform unmet biomedical and clinical needs into practical, usable technologies and products. With world class faculty and new initiatives in research and learning, BME at Georgia Tech/Emory is the go-to place for all those who want to actively shape the world and invent the future of health care!

exHIBITS

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Exhibits

Booth # 100

Hamamatsu Corporation 360 Foothill Road Bridgewater, NJ 08807 Phone: 908-231-0960 Email: [email protected] Web: www.hamamatsu.com Hamamatsu Corporation is the North American subsidiary of Hamamatsu Photonics K.K. (Japan), a leading manufacturer of devices for the generation and measurement of infrared, visible, and ultraviolet light. We offer low-light detectors, image sensors, light sources, and cameras (sCMOS, CCD, and EM-CCD) for biomedical applications.

and education. Our mission is to innovate in health care technology and train current and future clinicians and translational researchers from around the world in cutting edge health care advances. Booth # 114

IEEE Engineering in Medicine and Biology Society 445 Hoes Lane Piscataway, NJ 08854 Phone: 732-465-6460 Email: [email protected] Web: www.embs.org

Booth # 332

Houston Methodist Research Institute 6670 Bertner Street, MGJ Bldg. 9.019 Houston, TX 77030 Phone: 713-441-7267 Email: [email protected] Web: www.houstonmethodist.org Houston Methodist Research Institute’s mission of leading medicine is grounded in a commitment to translational and interdisciplinary research

Johns Hopkins Engineering Online and On-Site Part-Time Graduate Programs

ONLINE COURSES AVAILABLE

#1 RATED BEST JOB IN AMERICA BY CNNMONEY

diversity STUDENT BACKGROUNDS INCLUDE MECHANICAL, CHEMICAL, AND AEROSPACE ENGINEERING

LEARN MORE AT EP.JHU.EDU/ABE.

MS or Post-Master’s Certificate in Applied Biomedical Engineering

exHIBITS

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BMES 2014

For online education state authorization information, visit ep.jhu.edu/oesa

Exhibits Booth # 601

Booth # 600

IFS – Interactive Flow Studies

Izumi International

Billings, MT Phone: 612-810-2727 Email: [email protected] Web: www.interactiveflows.com

1 Pelham Davis Circle Greenville, SC 29615 Phone: 864-288-8001 Email: [email protected] Web: www.izumiinternational.com

Research and Educational Systems for Biomedical Engineers. Setup or upgrade your laboratory with our state of the art instruments. More information at www.interactiveflows.com Booth # 520

iWorx Systems Inc. 62 Littleworth Road Dover, NH 03820 Phone: 603-742-2492 x12 Email: [email protected] Web: www.iworx.com

Izumi International, Inc. designs and builds customized automated system and robotics for laboratories and R&D facilities. Izumi also integrates dispensing systems for the highest quality and highest precision dispensing in applications where conventional dispensing systems would not work. The vast range of dispensers and accessories make Izumi the one stop shop for all of your dispensing needs. Izumi will be demonstrating the new Aerojet non-contact dispenser, enabling world’s fastest jet dispensing of mid-high viscosity liquids for 3D Bioprinting applications.

iWorx introduces the HK-ELVIS Human Physiology/ Bioinstrumentation Teaching Kit. HK-ELVIS includes a 4 channel NI-ELVIS compatible breadboard with 2 transducer channels and 2 biopotential channels as well as the transducers, sensors and electrodes required to support a comprehensive suite of lab exercises. All transducers are also compatible with NI myDAQ.

Y

STUDENTS . . .

Interested in a career in academia, the medical device industry, or consulting? Prepare for any of these through graduate programs offered by Marquette University: M.S. in Biomedical Engineering Ph.D. in Biomedical Engineering

Visit at Boouts h 433

• Major research areas include imaging, rehabilitation engineering, robotics, modeling and computation, visualization and cardiovascular technologies M.S. in Healthcare Technologies Management (Marquette University & The Medical College of Wisconsin) • Unique 12 month program combines business, technology, and healthcare • Prepares graduates for career advancement and management positions with medical device companies, hospitals, and healthcare consulting firms M.E. in Biomedical Engineering (non-thesis) Ph.D. in Functional Imaging (Marquette University & The Medical College of Wisconsin) • Cutting-edge MR, MEG, CT and SPECT technologies; emphasizes clinical applications

For more information, visit marquette.edu/engineering/hctm or marquette.edu/engineering/bien exHIBITS

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Biomedical and Nanomedical Technology Publications ASME Press Concise Monograph Series • Ultrasonic Methods for Measurement of Small Motion and Deformation of Biological Tissues for Assessment of Viscoelasticity by Hideyuki Hasegawa and Hiroshi Kanai • Photodynamic Therapy Mediated by Fullerenes and their Derivatives by Michael R. Hamblin et al. • GFP Whole Cell Microbial Biosensors: Scale-up and Scale-Down Effects on Biopharmaceutical Processes by Frank Delvigne et al. • Biocompatible Nanomaterials for Targeted and Controlled Delivery of Biomacromolecules by D. Kapoor and S. Dhawan • Impedimetric Biosensors for Medical Applications Current Progress and Challenges by Jo V. Rushworth, et al. • Nanomaterials in Glucose Sensing by K. Burugapalli, N. Wang, J. Trzebinski, W. Song and A. Cass

ASME Journals

• Chitosan and Its Derivatives as Promising Drug Delivery Carriers by M. Prabaharan • Silica Nanoparticles as Drug Delivery System for Immunomodulator GMDP by E.V. Parfenyuk, N.A. Alyoshina, Yu.S. Antsiferova, N.Yu. Sotnikova

• Journal of Biomechanical Engineering • Journal of Fluids Engineering • Journal of Materials and Technology

• Nanoparticles and Brain Tumor Treatment by Gerardo Caruso, M.D., et al.

• Journal of Medical Devices

• Mobile Wearable Nano-Bio Health Monitoring Systems with Smartphones as Base Stations by Vijay K. Varadan and Linfeng Chen

• Journal of Micro and Nano-Manufacturing • Journal of Nanotechnology in Engineering and Medicine

ASME Conference Proceedings • International Mechanical Engineering Congress and Exposition (IMECE) • Frontiers in Medical Devices (BIOMED) • International Conference on Nanochannels, Microchannels, and Minichannels (ICNMM) • International Manufacturing Science and Engineering Conference (MSEC) • Global Congress on NanoEngineering for Medicine and Biology (NEMB) • Summer Bioengineering Conference (SBC) • Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS)

GET MORE INFORMATION Contact Warren Adams Email: [email protected]

DISCOUNTS ARE AVAILABLE FOR PACKAGE PURCHASES

Phone: 973-244-2223 Web: asmedigitalcollection.asme.org

exhibits Exhibits b Booths # 102

Johns Hopkins Engineering for Professionals 6810 Deerpath Road, Suite 100 Elkridge, MD 21075 Phone: 410-516-2300 Email: [email protected] Web: ep.jhu.edu The Johns Hopkins Engineering for Professionals Applied Biomedical Engineering (ABE) program gives practicing scientists the opportunity to enhance their skills in engineering so that they can solve today’s most critical problems in biology and medicine. Drawing from Johns Hopkins University’s acclaimed expertise in biomedical research and medical care, program faculty are able to impart real-world knowledge to their students—who are themselves notable professionals from diverse fields all over the world. The ABE program allows students to earn a M.S. degree in applied biomedical engineering through evening, weekend, and online courses, when work working professionals have time.

accomplishments. We will also be providing interviewing opportunities to prospective students, postdocs, and scientists through our research staff. Booth # 628

Louisiana Tech University Biomedical Engineering 818 Nelson Avenue #10157 / BMEB 103 Ruston, LA 71272 Phone: 318-257-4420 Email: [email protected],edu Web: www.latech.edu/biomedical-engineering Are you looking for a graduate program in a research university with small classes and friendly faculty? Please talk to us! Our research  areas include neural engineering/neuroscience; nanotechnology/applied  biotechnology; biosensors; advanced optical imaging; and cell,  molecular and tissue engineering. Plus we have clinical partners in epilepsy, TBI and cancer treatment.

Booth # 400 / 402

Booth # 101

Johns Hopkins University

Malvern Instruments/NanoSight

Department of Biomedical Engineering 720 Rutland Avenue Traylor 406 Baltimore, MD 21205 Phone: 410-614-4280 Email: [email protected] Web: www.bme.jhu.edu

117 Flanders Road Westborough, MA 01581 Phone: 508-768-6400 Email: [email protected] Web: www.malvern.com

Ph.D. Program – An intellectually stimulating environment and the nurturing spirit of collegiality extend throughout the program which is consistently ranked #1 in the US and has a long history of ground-breaking and innovative research and discovery. Research areas include bioinformatics and computational biology; cardiovascular systems; cell and tissue engineering; computational modeling; medical imaging; molecular and cell systems; and systems neuroscience. MSE Program – The master's degree program in the Department of Biomedical Engineering is designed for students who wish to pursue careers in research and development, academics (PhD or MD/PhD), or medicine. Students are given exposure to specialized biomedical engineering courses and participate in supervised research projects. CBID MSE Program – The Center for Bioengineering Innovation and Design is a translational research center that offers an intensive one-year master’s program that focuses on development and commercialization of medical devices that solve important clinical problems. Booths # 620 / 622

Korea Institute of Science and Technology (KIST) Hwarangno 14-gil 5, Seongbuk-gu Seoul 136-791 Republic of Korea Phone: +82-2-958-6087 Email: [email protected] Web: www.kist.re.kr The Biomedical Research Institute at KIST is Korea’s leading medical research agency. Making important discoveries that improve health and save lives, we invite you to learn more about our institute and research

Malvern supports better characterization/control of proteins/ macromolecules. Charge, size, mass, molecular weight, polydispersity are critical parameters, measured using: Zetasizer, dynamic/static light scattering for size, molecular weight, protein charge; NanoSight Nanoparticle Tracking Analysis, particle-by-particle characterization; Viscotek SEC, molecular weight/ structure; Sysmex FPIA-3000, size/shape analysis of aggregates/ subvisible particles; Viscosizer 200, particle size, concentration, formulation viscosity. Booth # 433

Marquette University P.O. Box 1881 Milwaukee, WI 53201 Phone: 414-288-6059 Email: [email protected] Web: www.mu.edu Healthcare Technologies Management Program (Marquette University and the Medical College of Wisconsin): Unique graduate curriculum combines business, technology, and healthcare to prepare engineers for management positions with medical device companies, hospitals, and healthcare consulting firms.  Full time students can earn the MS degree in Healthcare Technologies Management in one year. The graduate program in biomedical engineering at Marquette University offers MS, ME, and PhD degrees in Biomedical Engineering.  Research opportunities are available in areas such as rehabilitation engineering, neurosystems, cardiovascular and pulmonary medicine, imaging, biomechanics, orthopedics, and others.  The program is recognized for strong industry ties and research collaborations with the Medical College of Wisconsin, Froedtert Hospital, Children’s Hospital of Wisconsin, Zablocki VA Medical Center, and Shriner’s Hospital (Chicago).     

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Booth # 309

Booth # 226

Mayo Graduate School

National Institute of Biomedical Imaging and Bioengineering

Biomedical Engineering & Physiology Mayo Clinic Rochester 200 First Street, SW, SMH J04-184 Rochester, MN 55905 Phone: 507-255-8544 Email: [email protected] Web: www.mayo.edu/,gs/programs/phd/biomedical-engineering The Mayo Graduate School, part of the Mayo Clinic, offers a graduate program leading to the Ph.D. and M.D./Ph.D. with an educational background and laboratory experience that prepares them for careers as independent research investigators.  The Graduate Program in Biomedical Engineering & Physiology has a long, rich history at Mayo with a tradition of translational research that spans interdisciplinary boundaries and routinely connects the engineering and physical sciences to the biological sciences and clinical practice. The Graduate Program in Biomedical Engineering & Physiology offers a wide range of research opportunities from basic discovery science to clinical research. Students are provided the necessary quantitative tools to become leaders in diverse fields of biomedical sciences. 

31 Center Drive, Room 1C14 Bethesda, MD 20892 Phone: 301-496-9208 Email: [email protected] Web: http://www.nibib.nih.gov The mission of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) is to improve human health by leading the development and accelerating the application of biomedical technologies. The Institute is committed to integrating the physical and engineering sciences with the life sciences to advance basic research and medical care. Stories of exciting research breakthroughs are told through video and web content at www.nibib.nih.gov.  In addition to funding research, NIBIB supports a broad range of training programs from undergraduate to post-doctoral students. These programs are designed to support researchers throughout the career continuum, increase the number of clinician-scientists, and enhance the participation of underrepresented populations in biomedical imaging and bioengineering research. Booth # 123

Booth # 117

McGill University Department of Bioengineering 817 Sherbrooke Street West, Room 270 Montreal, Quebec H3A 0C3 Canada Phone: 514-398-7138 Email: [email protected] Web: www.mcgill.ca/bioengineering McGill University is a leading research-intensive academic institution in Canada. The Department of Bioengineering (Faculty of Engineering) aims to maintain McGill’s international reputation of excellence in research and teaching. The Department has a graduate program co-administered with the Department of Biomedical Engineering (Faculty of Medicine) and is developing an undergraduate program. Booth # 422

Morgan & Claypool Publishers 1537 Fourth Street, Suite 228 San Rafael, CA 94901 Phone: 415-785-8003 Email: [email protected] Web: www.morganclaypool.com Morgan & Claypool is a leading digital publisher of books in biomedical and tissue engineering. All titles are brief, focused treatments of core topics in teaching and research, perfect for beginning or advanced students, practicing researchers, and faculty. Stop by our booth and talk to us about getting access to our online collection, or about becoming an author. Visit us online at www.morganclaypool.com/r/bme.

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New Jersey Institute of Technology Department of Biomedical Engineering Fenster Hall – 6th Floor 323 Dr. Martin Luther King Blvd. Newark, NJ 07102 Phone: 973-596-5268 Email: [email protected] Web: http://biomedical.njit.edu/academics/index.php Biomedical engineering is the youngest engineering department at the New Jersey Institute of Technology (NJIT) and offers bachelor’s, master’s and doctoral degrees. The program has grown rapidly and today NJIT is among the top producers of biomedical engineering degrees in the region. In addition to the bachelor’s program, the graduate programs are also a significant part of the department’s total educational offerings. NJIT’s master’s program is the second largest nationally. Our doctoral program was ranked by the National Research Council 26th out of 76 nationally in curriculum quality and student accomplishment. We have a strong research program with expertise in neural and neuromuscular engineering, and tissue engineering/regenerative medicine. Booth # 115

The New York Times 613 South Avenue Weston, MA 02493 Phone: 781-890-2661 Email: [email protected] Web: www.nytimes.com

Exhibits

Booth # 632

North Carolina A&T State University Chemical, Biological and Bioengineering Department 1601 E. Market Street McNair Hall 341 Greensboro, NC 27411 Phone: 336-285-2653 Email: [email protected] Web: http://www.ncat.edu/academics/schools-colleges1/coe/cbbe/index.html NC A&T’s Bioengineering BS and MS degree programs, the first at an HBCU, prepare students to address problems at the forefront of biomedical engineering through education and advanced research. Programs emphasize the bioengineering practice and research in biomaterials, biomechanics, tissue engineering and biosensors with musculoskeletal, drug delivery and cardiovascular applications. Booth # 404

Northwestern University 2145 Sheridan Road Evanston, IL 60026 Phone: 847-467-2369 Email: [email protected] Web: www.bme.northwestern.edu With cutting-edge research in Biomaterials and Regenerative Medicine, Imaging and Biophotonics, and Neural Engineering, Northwestern University BME attracts top faculty and students alike. Research takes place on the main campus in Evanston and on the medical school campus in downtown Chicago. Booth # 236

The Ohio State University Department of Biomedical Engineering 270 Bevis Hall, 1080 Carmack Road Columbus, OH 43210 Phone: 614-292-7152 Email: [email protected] Web: www.bme.osu.edu Offering B.S., M.S., Ph.D., and M.D./Ph.D. degrees with research in biomechanics/biotransport; biomaterials; bioimaging; tissue engineering; biomedical devices, and micro/nanotechnology at state-of-the-art facilities including The Ohio State University Wexner Medical Center, Davis Heart and Lung Research Institute, Institute for Materials Research, Comprehensive Cancer Center, and Nationwide Children’s Hospital of Columbus.  Booth # 421

Pennsylvania State University 205 Hallowell Building University Park, PA 16801 Phone: 814-865-1407 Email: [email protected] Web: www.bme.psu.edu The Penn State Department of Biomedical Engineering and the Intercollege Graduate Degree Program in Bioengineering are proud to offer B.S., M.S. and Ph.D. degrees. Our mission is to educate students to become

world-class engineers who contribute to social and economic development through innovative solutions to problems in medicine and the life sciences. The graduate program offers strong integration with many other disciplines to increase the breadth of our uniquely trained faculty and specialized facilities, enable cutting-edge research in fundamental biology, medical device design, and disease diagnosis, with a goal to translate discovery from academia to society. Come by for a visit. We look forward to meeting you! Booths # 408 / 410

Purdue University Weldon School of Biomedical Engineering 206 S. Martin Jischke Drive West Lafayette, IN 47907-2032 Phone: 765-494-2995 Email: [email protected] Web: www.purdue.edu/bme The Weldon School of Biomedical Engineering at Purdue is undergoing significant programmatic and faculty growth to meet the rising demands of the medical device and biotechnology industries. Opportunities abound in our expanding graduate programs, signature areas of research, and entrepreneurial partnerships. Ask us about our unique specialty programs in Regulatory Affairs for Medical Devices and Biomedical Entrepreneurship. We offer seven major tracks to a graduate degree, including a Professional MS Program. All qualified graduate students are fully funded. Booth # 522

Rensselaer Polytechnic Institute 110 8th Street, BMED JEC7049 Troy, NY 12180 Phone: 518-276-6548 Email: [email protected] Web: www.bme.rpi.edu Rensselaer Polytechnic Institute is the nation’s oldest technological research university and home to one of the oldest biomedical engineering departments. Educating outstanding academics, industry leaders and research scientists.  Research is centered on Biomolecular Science and Engineering, Biomedical Imaging, Musculoskeletal Engineering, Neural Engineering, Systems Biology and Biocomputation, and Vascular Engineering (bme.rpi.edu). Booths # 535 / 537

Rice University Department of Bioengineering 6100 Main Street Houston, TX 77005-1892 Phone: 713-348-5869 Email: [email protected] Web: www.bioengineering.rice.edu Rice University’s Department of Bioengineering is a top-tier teaching and research institution with graduate programs that lead to an MBE, PhD, or a joint MD/PhD with Baylor College of Medicine. Situated next to the Texas Medical Center, we offer education and research opportunities in biomaterials and drug delivery, biomedical imaging and diagnostics, cellular and bimolecular engineering, computational and theoretical bioengineering, systems and synthetic biology, and tissue engineering and biomechanics. BMES 2014

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Booth # 222

Rutgers University 599 Taylor Road Piscataway, NJ 08854 Phone: 848-445-4500 Email: [email protected] Web: http://biomedical.rutgers.edu The Rutgers Department of Biomedical Engineering (BME) is a vibrant and dynamic enterprise of scholarship, learning, and technology development. Located in the heart of New Jersey’s “Cure Corridor”, BME offers a remarkably diverse array of opportunities for undergraduate, graduate, and postgraduate training and research in molecular systems bioengineering, biomaterials and tissue engineering, bionanotechnology, biomechanics, rehabilitation engineering, and biomedical imaging.

Booth # 137

Secant Medical, Inc. 700 W. Park Avenue Perkasie, PA 18944 Phone: 877-774-2835 Email: [email protected] Web: www.secantmedical.com Secant Medical provides advanced biomaterials and biomedical textile structures to the medical device industry. We partner with clients to design, develop, and manufacture high-performance biomedical structures for a variety of applications.  We’re committed to the future of regenerative medicine and actively engage in research partnerships to advance next-generation biomaterial technology. Booth # 111

Springer 233 Spring Street New York, NY 10013 Phone: 212-460-1500 Email: [email protected] Web: www.springer.com Springer is proud to be the publisher of Annals of Biomedical Engineering, Cellular & Molecular Bioengineering and Cardiovascular Engineering and Technology. Visit our booth to explore our full range of print and electronic publications in Biomedical Engineering. Booth # 129

Stanford Bioengineering 443 Via Ortega Stanford, CA 94305-4125 Phone: 650-723-8632 Email: [email protected] Web: bioengineering.stanford.edu Booth # 120

Stevens Institute of Technology Castle Point on Hudson Hoboken, NJ 07030 Phone: 201-216-5000 Email: [email protected] Web: www.stevens.edu/sit/ As one of the nation’s leading research universities, Stevens displays a unique pedagogical model that includes productive research programs with world-class facilities. Graduate students can choose from 22 PhD programs and 43 master’s programs. All Stevens students benefit from a distinguished faculty displaying exacting scientific, academic and entrepreneurial standards.

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Booth # 335

Booth # 305

Temple University

Texas A & M University

College of Engineering / Bioengineering 1947 N. 12th Street Philadelphia, PA 19122 Phone: 215-204-3404 Email: [email protected] Web: http://engineering.temple.edu/bioengineering

Department of Biomedical Engineering 3120 TAMU College Station, TX 77843-4462 Phone: 979-845-2312 Email: [email protected] Web: http://engineering.tamu.edu/biomedical

Temple’s Bioengineering Department officially started back in 2012 with Master’s and PhD students.  The undergraduate curriculum commenced in the Fall of 2013.  Departmental financial support options are available for students. Temple U., in addition, started a Presidential Fellowship program for both graduate and undergraduate students. Faculty expertise includes cellular and regenerative tissue engineering, neuroengineering, biomechanics, biomaterials, molecular engineering, spectroscopy, and microscopy.  We have a strong emphasis on interdisciplinary collaborations and translational research, leveraging strategic initiatives and institutional strengths in Medicine, Pharmacy, and Oncology. 

The Department of Biomedical Engineering at Texas A&M University offers an opportunity to participate in ground-breaking research in sensing and imaging, optics, orthopedic biomechanics, biomaterials, tissue engineering and more. The department’s award-winning faculty members have strong collaborations with medical and veterinary schools as well as industry. Offering graduate degree options at the master’s (M.S. ,M.Eng., M.Eng./MBA) and doctoral (Ph.D. & D.Eng.) levels, this program provides an exceptional academic experience.

The Department of Biomedical Engineering School of Medicine School of Engineering

  

Biomedical Implants & Devices Cardiac Electrophysiology Multiscale Computational Biology

Booth #320

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Tissue Engineering & Regenerative Medicine Biomaterials, Biomechanics & Drug Delivery Biomedical Imaging & Optics

Degree Programs  Ph.D.  M.D./Ph.D. & D.M.D./Ph.D.  Master’s of Science  Master’s in BME with a Certificate in Technology Commercialization and Entrepreneurship www.eng.uab.edu/bme exHIBITS

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Booths # 426 / 428

Booth # 605

Tufts University

Tulane University

Biomedical Engineering 4 Colby Street Medford, MA 02155 Phone: 614-627-2580 Email: [email protected] Web: www.engineering.tufts.edu/bme

500 Lindy Boggs Bldg. New Orleans, LA 70118 Phone: 504-314-2926 Email: [email protected] Web: www.bmen.tulane.edu

Biomedical Engineering at Tufts University draws from core disciplines such as engineering, biology, computer science, physics, chemistry, and physiology, emphasizing an interdisciplinary approach to research and education. Strong emphasis is placed on interactions with faculty in Arts and Sciences and the professional schools. The Tissue Engineering Resource Center (TERC) was initiated in August of 2004 as a Resource Center supported through the National Institutes of Health P41 program. The core themes in the Center focus on functional tissue engineering achieved through a systems approach—integrating cells, scaffolds and bioreactors to control the environment in vitro for translation in vivo.

Tulane’s Biomedical Engineering Department is located in the diverse cultural mecca of New Orleans and has been established since 1977. Degrees offered range from B.S. to Ph.D., and research includes biomechanics, biotransport, regenerative medicine, biomaterials and devices. Collaboration with the School of Medicine and numerous other centers are available and abounding.

http://engineering.ucdenver.edu/BIOE

APPLYING ENGINEERING SOLUTIONS TO HEALTH-RELATED PROBLEMS Bioengineering at University of Colorado Denver | Anschutz Medical Campus: a comprehensive bioengineering education on a world-class medical campus where students get hands-on experience with faculty, clinicians, and industry professionals. Degrees offered: BS, MS, PhD Dual degrees: MD/PhD, MS/MBA, MD/MS Research areas: Cardiovascular biomechanics and hemodynamics Diabetes Imaging Biophotonics Rehabilitation engineering and assistive technology Neuromuscular control and neuroscience engineering Spinal and orthopedic biomechanics Vascular surgery and interventional radiology Polymers and drug delivery Biomedical entrepreneurship exHIBITS

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Booth # 336

The University of Akron Department of Biomedical Engineering 302 Buchtel Common Akron, OH 44325-0302 Phone: 330-972-6650 Email: [email protected] Web: bme.uakron.edu The Department of Biomedical Engineering at The University of Akron offers two graduate degree programs: a master’s degree in engineering with a biomedical specialization and a Ph.D. in engineering. These programs have an individualized curricular approach, designed in coordination with each student’s career plans. BME faculty are engaged in a variety of research areas, including but not limited to, instrumentation, biomaterials, biomechanics, and tissue engineering. Our faculty have active collaborations both on campus and with researchers in regional health care institutions and biomedical industry. We encourage interdisciplinary interactions to promote vibrant research activities and to provide an exceptional scholarly atmosphere for learning. The BME Department currently has 17 full-time and joint faculty, including 8 recent hires, 3 endowed chairs, and 2 CAREER award recipients. Booth # 320

The University of Alabama at Birmingham Department Biomedical Engineering 1825 University Boulevard, SHEL 801C Birmingham, AL 35294-2182 Phone:  205-996-6936 Email: [email protected] Web: www.eng.uab.edu/bme The Biomedical Engineering (BME) Graduate Program at The University of Alabama at Birmingham offers Master’s and PhD degrees. The BME Department has a joint status in the School of Engineering and School of Medicine with a strong record of interdisciplinary research in biomaterials, biomechanics, biomedical imaging, cardiac electrophysiology, computational biology, tissue engineering and regenerative medicine. The BME Graduate Program has over 60 primary and secondary faculty training students to develop the next generation of technologies. BME graduates find employment in universities, health care, medical devices, pharmaceuticals, and regulatory agencies. Booth # 322

The University of Arizona Biomedical Engineering / GIDP Program P.O. Box 21240 Tucson, AZ 85721 Phone:  520-629-9134 Email: [email protected] Web: www.bme.arizona.edu

es Colleges facilitates cutting-edge translational research in specialties such as cardiovascular engineering, imaging, nanotechnology, computational modeling and entrepreneurship. Booth # 610

University of Arkansas College of Engineering 3189 Bell Engineering Center Fayetteville, AR 72701 Phone: 479-575-4667 Email: [email protected] Web: www.engr.uark.edu The Biomedical Engineering Program at the University of Arkansas offers MS and PhD degrees. Our active faculty has research programs in: Organ Regeneration; Cell and Molecular Imaging; Nanobiotechnology; Molecular Genetics and Cell Biology in Disease Prevention; Biomaterials; Tissue Engineering; and Vaccine and Immunotherapy Delivery Systems. Stop by our booth and learn how well qualified students can earn $10,000 to $20,000 per year on top of standard assistantship stipends! Booth # 636

University of California, Berkeley 306 Stanley Hall #1762 Berkeley, CA 94720-1762 Phone: 510-642-5833 Email: [email protected] Web: http://bioeng.berkeley.edu/ The Department of Bioengineering at the University of California, Berkeley will be showcasing its novel research and academic programs including BS, MEng (Master of Engineering), MTM (Master of Translational Medicine), and PhD degrees. Come visit the UC Berkeley booth to speak with representatives and learn more about the department. Booth # 337

The University of California at Davis Department of Biomedical Engineering One Shields Avenue Davis, CA 95616 Phone: 530-752-1033 Email: [email protected] Web: www.bme.ucdavis.edu With 33 primary faculty and a graduate group of ~70 faculty, BME at UC Davis combines exceptional teaching with state-of-the-art research to prepare students for careers in academics and industry. Come learn about our programs in bioinformatics, biomechanics, cellular and molecular systems, imaging, synthetic biology, and tissue engineering and regenerative medicine.

The University of Arizona’s Biomedical Engineering Graduate Interdisciplinary Program offers opportunities to integrate engineering, mathematics, biology, and medicine in a collaborative multi-disciplinary environment with over 60 faculty mentors.  Proximity to Medicine, and Health SciencexHIBITS

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Booth # 302

University of California, Irvine 3120 Natural Sciences II Irvine, CA 92697-2715 Phone: 949-824-9196 Email: [email protected] Web: www.bme.uci.edu The UCIrvine Department of Biomedical Engineering’s mission is to inspire engineering minds for the advancement of human health.  Engineering focus areas include biomedical photonics/optoelectronics, biomedical nano- and microscale systems/fabrication, biomedical computation/modeling, and tissue engineering. These technology areas intersect with clinical areas of focus such as cardiovascular disease, the nervous system, cancer, and ophthalmology. Included in these opportunities are major campus research centers at the Beckman Laser Institute (biophotonics), the Edwards Lifesciences Center for Advanced Cardiovascular Technology, the Chao Family Comprehensive Cancer Center, the Integrated Nanosystems Research Facility, the Laboratory of Fluorescence Dynamics, and the Micro/nano Fluidics Fundamentals Focus Center. UCI is located in Orange County, home to more than 300 medical device companies. Booth # 104

University of California, Riverside Department of Bioengineering 900 University Avenue Riverside, CA 92521 Phone: 951-827-4303 Email: [email protected] Web: www.bioeng.ucr.edu The Department of Bioengineering, established in 2006, is the fastest growing department at the Bourns College of Engineering. The research vision is to build strength from expertise in biochemistry, biophysics, biology, and engineering to focus on critical themes that impact bioengineering. The mission of the Department of Bioengineering at the University of California, Riverside focuses on two interrelated themes: 1) advancing bioengineering research, and 2) preparing future leadership in bioengineering and related fields. Our unique interdisciplinary graduate program and ABET-accredited undergraduate program both combine building a solid fundamental foundation in biological science and engineering while simultaneously developing diverse communication skills for our students. Bioengineering Interdepartmental Graduate Program (BIG) provides additional training in analytical, computational and laboratory skills in the most advanced quantitative bioengineering research. The result is a rigorous but exceptionally interactive and welcoming educational training for Bioengineering students leading towards B.S, M.S. and Ph.D. degrees.

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Booth # 536

University of Colorado Denver | Anschutz Medical Campus Department of Bioengineering 12700 E. 19th Avenue, Research 2 Building Room 6018, MS 8607 Aurora, CO 80045 Phone: 303-724-5893 Email: [email protected] Web: www.ucdenver.edu/bioengineering Located on a medical campus, we are integrated with world-class hospitals and the nationally ranked CU School of Medicine. In addition to traditional undergraduate and graduate degrees, we offer a dual MS-MBA, MD-MS and MD-PhD. Our students work with top faculty and researchers on projects that range from basic research to clinical applications and commercialization of medical technologies through our entrepreneurship pathway. Booth # 626

University of Connecticut Biomedical Engineering 260 Glenbrook Road, Unit 3247 Storrs, CT 06269 Phone: 860-486-0163 Email: [email protected] Web: www.bme.uconn.edu The ABET-accredited Undergraduate program and the long-standing MS/ PhD Program in Biomedical Engineering at the University of Connecticut are now under the auspices of the Biomedical Engineering Department, which spans the School of Engineering (Storrs) and the Schools of Medicine and Dental Medicine (Farmington), offering our students ready access to cutting-edge research and outstanding faculty members/ practitioners on both campuses. We also offer one of the few Clinical Engineering Internship programs (MS) in the country. Booth # 235

University of Delaware Biomedical Engineering 125 E. Delaware Avenue Newark. DE 19716 Phone: 302-831-2120 Email: [email protected] Web: www.bme.udel.edu University of Delaware Biomedical Engineering offers undergraduate and graduate programs and we welcome intellectually motivated, creative, and diverse individuals who wish to benefit from our educational and research programs. Our research programs cross the following areas: Biomolecular Engineering, Cellular Engineering & Systems Biology; Tissue Engineering, Biomaterials & Drug Delivery; Rehabilitation Engineering & Neuroengineering; Biomechanics; Bioimaging, Bio-computing & Bioelectronics.

Exhibits

Booth # 209

Booth # 434

University of Florida

University of Houston

Department of Biomedical Engineering 1275 Center Drive Biomedical Sciences Building JG-56 P.O. Box 116131 Gainesville, FL 32606 Phone: 352-273-9222 Email: [email protected] Web: www.bme.ufl.edu

Department of Biomedical Engineering 3605 Cullen Blvd. Houston, TX 77024 Phone: 832-842-8887 Email: [email protected] Web: www.bme.uh.edu

UF BME is made possible by the vision and generosity of Dr. J. Crayton Pruitt and his family. Since its inception in 2002, the department continues to excel in interdisciplinary research that merges engineering with biology and medicine. The department offers both a graduate program and an undergraduate program (2012 inaugural class), with particular strengths in Neural Engineering, Imaging and Medical Physics, Biomaterials and Tissue Engineering, and Biomechanics and Modeling. In the past year, the department has grown to 21 faculty and will continue that growth up to 25-30.  UF BME is one of only a few departments in the nation to be co-localized with a top-ranked medical school, veterinary school, and dental school. The department is also uniquely positioned to contribute to clinical translation of biomedical technologies because of the outstanding resources for entrepreneurship and commercialization in the Gainesville area.

Our main goal is to develop leadership in academia, government, and industry nationally and globally. The importance of global scientific, social, and cultural interaction and the demands of the dynamic, ever-changing global healthcare economy have been strongly emphasized in our undergraduate and graduate programs. The research in the graduate program focuses on three main areas, neural, cognitive, and rehabilitation engineering, biomedical imaging, and bionanoscience.

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Booth # 221

Booth # 227

University of Illinois at Chicago

University of Illinois at Urbana-Champaign

851 S. Morgan Street, Room 28 Chicago, IL 60607-7052 Phone: 312-996-5225 Email: [email protected] Web: www.bioe.uic.edu One of the first degree granting and accredited Bioengineering programs in the nation, since 1965 UIC Bioengineering offers B.S, M.S, Ph.D., M.D./ M.S. and M.D./Ph.D. programs that emphasize translational research and innovative training that can include clinical immersion and industry-linked interdisciplinary medical product development.  The Richard and Loan Hill Department of Bioengineering is led by core faculty who collaborate with leading faculty in five major academic medical centers in Chicago - including UIC, home of the largest medical school in the country.

bme.umich.edu

Department of Bioengineering 1304 W. Springfield Avenue Room 1270 Digital Computer Laboratory Urbana, IL 61801 Phone: 217-333-1867 Email: [email protected] Web: www.bioengineering.illinois.edu The Graduate Program in the Department of Bioengineering at the University of Illinois at Urbana-Champaign provides students with educational and research experiences that integrate the sciences of biology and medicine with the practices and principles of engineering. Areas of focus include Bioimaging; Bio-Micro/Nanotechnology; Molecular, Cellular & Tissue Engineering; Computational Bioengineering; and Synthetic Bioengineering. The department offers studies leading to the Master of Science in Bioengineering and the Doctor of Philosophy in Bioengineering. Beginning in Fall 2015, a professional master’s degree in Bioinstrumentation also will be available. Opportunities also exist for specializing in computational science and engineering or in energy and sustainability engineering via the Computational Science and Engineering (CSE) Option and the Energy and Sustainability Engineering (EaSE) Option. And highly qualified Bioengineering students enroll in the Medical Scholars Program (MD/PHD), which integrates the study of medicine with a doctoral degree in Bioengineering. Booth # 432

University of Iowa 1402 Seamans Center Iowa City, IA 52242 Phone: 319-335-5632 E-mail: [email protected] Web: www.engineering.uiowa.edu/bme

Photo by Brandon Baier, Biomedical Engineering

U-M BME provides leadership in education, training and cutting-edge research by translating science and engineering to solve important challenges in medicine and life sciences to the benefit of humanity.

The University of Iowa Department of Biomedical Engineering offers graduate research programs in the following research areas:  Biomedical Imaging, Biomaterials, Cardiovascular Biomechanics, Bioinformatics, Musculoskeletal Biomechanics, Tissue Engineering and Cellular Analysis. The Department is located close to a tertiary-care  teaching hospital, and near the Colleges of Dentistry, Medicine, Nursing, and Public Health. Iowa City is ranked number 4 in the Top 10 College Destinations (AIER), is a UNESCO City of Literature, and is a Top 100 Adventure City (NatGeo Adventure).  Stop by our booth for more information.

U-M BME is a joint department between the top-ranked U-M College of Engineering and top-ranked U-M Medical School that fosters collaboration between engineers and physicians to accelerate discovery of healthcare technology. With the support of the Wallace H. Coulter Translational Research Partnership Program, U-M BME embraces the translation of research into lifesaving technologies. @UMBME

facebook.com/umbme

exHIBITS

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Exhibits

Booth # 327

Booth # 223

University of Kansas

University of Maryland

Bioengineering Graduate Program 1520 West 15th, Room 1, Eaton Hall Lawrence, KS 66045 Phone: 785-864-5258 E-mail: [email protected] Web: www.bio.engr.ku.edu

Fischell Department of Bioengineering 2330 Jeong H. Kim Building College Park, MD 20742 Phone: 301-405-7426 Email: [email protected] or [email protected] Web: http://www.bioe.umd.edu

KU Bioengineering is an exciting and dynamic place. Our curriculum is broad and flexible, embracing the interdisciplinary nature of the field.  With six tracks; Bioimaging, Bioinformatics, Biomolecular, Biomedical Product Design & Development, Biomechanics & Neural, and Biomaterials & Tissue; and a collaboration with the University of Kansas Medical Center, students customize their education and create a niche of research before they enter the job market.

Faculty and students in the Fischell Department of Bioengineering at UMD are committed to  making a difference in human health care through education, research, and invention.  We have exciting collaborations with the FDA, NIH-NCI, UMB Pharmacy and Medicine, and Children’s National Medical Center and offer programs leading to the BS, M.Eng., MS/MD, MD/PhD and PhD degrees.

Pitt Graduate ProGram

In BIOenGIneeRInG

One of our distinctive strengths in interdisciplinary research is our relationship with Pitt’s School of Medicine and Schools of the Health Sciences, as well as with the McGowan Institute for Regenerative Medicine. Bioengineering is also deeply embedded within clinical research at University of Pittsburgh Medical Center, one of the top ranked hospital networks in the country. Faculty have laboratories within clinical departments, which allow graduate students to apply engineering principles directly to patient care in bench-to-bedside settings. Most importantly for our graduate students, Pitt is an urban campus in one of the most livable cities in the world. Its world-class research institutions, corporate headquarters, public amenities, healthcare, low cost of living and relative safety have earned Pittsburgh accolades from Forbes, Kiplingers, National Geographic, The Economist, and US News & World Report. Both the University and the City provide the perfect match for an outstanding graduate school environment. exHIBITS

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Please visit

engineering.pitt.edu/bioengineering for a detailed description of graduate program information including our admissions process and various research focus areas.

Exhibits

Booth #333

Booth # 511

University of Memphis University of Tennessee Health Sciences Center

University of Minnesota

Biomedical Engineering 330 Engineering Technology Building Herff College of Engineering Memphis, TN 39152-3210 Phone: 901-678-3733 Email: [email protected] Web: www.memphis.edu/bme The UM/UT Joint Graduate Program offers M.S. and Ph.D. degrees in biomedical engineering with research specialization in biomaterials, tissue engineering, drug delivery, biomechanics, biomedical sensors, electrophysiology, and bioimaging. Emphasis in these disciplines is in dental/orthopedics, computational models (pulmonary, coronary, and muscoskeletal), sensor nano/microfabrication, and image processing and analyses.

Department of Biomedical Engineering 312 Church St. SE 7-105 Nils Hasselmo Hall Minneapolis, MN 55455 Phone: 612-624-8396 E-mail: [email protected] Web: www.umn.edu/bme The Department of Biomedical Engineering at the University of Minnesota is physically located at the intersection of the medical school, engineering, and physical sciences, and in the heart of LifeScience Alley (home to Medtronic, Boston Scientific, St. Jude Medical, Covidien, plus 500 other FDA-registered medtech companies).  Research conducted by the faculty spans the full spectrum, with particular depth in cardiovascular/neural engineering, cell/tissue engineering, cancer bioengineering, and biomedical imaging/optics.

Booth # 435

University of Miami Department of Biomedical Engineering 1251 Memorial Drive, MEA #219A Coral Gables, FL 33146-0621 Phone: 305-284-2445 Email:  [email protected] Web:    www.bme.miami.edu Our undergraduate and graduate programs leading to the B.S., 5 year B.S./M.S, M.S and Ph.D. degrees provide graduates with the analytical and design skills required to solve problems at the interface of engineering and life sciences. Special features of our program include small class size, very strong ties with the University of Miami Miller School of Medicine, high level of student-faculty interaction, and a high percentage of undergraduate student participation in research and professional activities. The research areas of our Faculty include biomedical imaging, optics and lasers; neural engineering, biosignals and instrumentation; and biomechanics, biomaterials and tissue engineering. Booth # 301

University of Michigan Department of Biomedical Engineering 1111 Carl A. Gerstacker Building 2200 Bonisteel Blvd. Ann Arbor, MI 48109-2099 Phone: 734-763-5290 E-mail: [email protected] Web: www.bme.umich.edu The University of Michigan Department of Biomedical Engineering provides an outstanding educational experience for engineers in biomedical engineering and develops future leaders in the field. The program’s primary emphasis is on biomedical engineering fundamentals, while allowing students to personalize their curriculum to prepare them for a wide variety of careers including biomedical engineering, law, medicine, and business.

Sc h Av ola ai rsh la bl ips e!

The Department of Bioengineering at UT Arlington offers research and scholarship opportunities in • Tissue Engineering • Medical Imaging • Biomechanics To learn more, click on “Future Students” at

uta.edu/bioengineering

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Exhibits

Booth # 135

Booths # 614 / 616

University of North Carolina at Chapel Hill and NC State University

University of Pittsburgh

137 MacNiber Hall Chapel Hill, NC 27599 Phone: 919-966-8088 Email: [email protected] Web: www.bme.unc.edu The Joint Department of Biomedical Engineering is an academic department co-located at the University of North Carolina at Chapel Hill and NC State University and was established on December 1, 2003, linking the School of Medicine at UNC-CH to the College of Engineering at NC State. The graduate program offers joint MS and PhD degrees in Biomedical Engineering. The department has administrative offices on both campuses (NCSU: 4130 Engineering Building III; UNC-CH: 152 MacNider Hall).

Department of Bioengineering 300 Technology Drive Pittsburgh, PA 15219 Phone: 412-624-6445 Email: [email protected] Web: engineering.pitt.edu The University of Pittsburgh Department of Bioengineering conducts world-class research and is home to faculty and students at both the graduate and undergraduate level who have won both nationally and internationally recognized awards. The department also has a close affiliation with the renowned University of Pittsburgh School of Medicine.

A Closely Knit Community Nestled into Utah’s Wasatch Mountain range, the Department of Bioengineering’s new home (foreground) is located between the University Hospital & School of Medicine (upper left) and the College of Engineer Campus (just to the right out of frame) providing a clinically immersive engineering experience that is unique among BME training programs. Did you know that the Department of Bioengineering is one of the oldest and yet fastest growing Biomedical training programs in the nation. We rank 7th nationally in median h-index for core faculty as determined by google scholar. With over 125 faculty our research strengths span every inch of Clinical medicine. Not to mention that we are surrounded by unprecedented natural beauty. Learn more about us at: http://www.bioen.utah.edu/ exHIBITS

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Exhibits

booth # 323

Booth # 217

University of Rochester

University of Texas Arlington

Department of Biomedical Engineering 204 Robert E. Georgen Hall Rochester, NY 14627 Phone: 585-273-2353 Email: [email protected] Web: www.bme.rochester.edu

Bioengineering Department 500 UTA Blvd., Suite 226 Arlington, TX 76010 Phone: 817-272-2249 Email: [email protected] Web: www.uta.edu/bioengineering

The Graduate Program in Biomedical Engineering at the University of Rochester provides training at the Masters and Doctoral level.  Multiple active centers and affiliated groups offer collaborative research in Biomedical Optics; Neuroengineering; Biomechanics; Medical Imaging; Biomaterials, Nanotechnology and Cell & Tissue Engineering.  With access to over 50 laboratories on the River Campus and the adjacent Medical Center, students can tailor their own interdisciplinary and translational training experience. We also offer an MS program focused on Medical Technology & Innovation, including a clinical practicum and full-year design experience.

The Bioengineering Department at the University of Texas Arlington offers several research and scholarship opportunities for students interested in Biomaterials & Tissue Engineering, Bioinstrumentation, Biomechanics, and Medical Imaging. Graduate students also have the option of earning a joint graduate degree with The University of Texas Southwestern Medical Center at Dallas. Undergraduate students are strongly encouraged to learn more about our new Undergraduate Program in Biomedical Engineering at UT Arlington.  Please visit our booth at the exhibit to learn more!  

Booth # 515

University of Southern California (USC) Viterbi School of Engineering 3650 McClintock Ave, OHE 106 Los Angeles, CA 90089 Phone: 213-740-0119 Email: [email protected] Web: http://viterbi.usc.edu/gapp The USC Viterbi School of Engineering’s top 10 ranked graduate program offers Master’s and Doctoral programs in a wide range of disciplines. Learn more about our unique programs, including Biomedical Engineering, Medical Imaging, Neuroengineering, Medical Devices and Wireless Health Technology at viterbi.usc.edu/gapp. Booths # 503 / 505

University of Tennessee - Knoxville 1512 Middle Drive 414 Dougherty Engineering Bldg Knoxville, TN 37996 Phone: 865-974-5115 Email: [email protected] Web: http://mabe.utk.edu The department of Mechanical, Aerospace and Biomedical Engineering at the University of Tennessee offers B.S., M.S., and Ph.D. degrees in Biomedical Engineering.   Graduate level research in Biomedical Engineering are organized as interdisciplinary and across departmental and college boarders through the Institute of Biomedical Engineering (iBME). In iBME, faculty from the College of Engineering, the Graduate School of Medicine, the College of Veterinary Medicine, and the College of Education, Health, and Human Sciences work collaboratively to teach a wide variety of courses and perform research in seven major thrust groups.  Current thrust groups include Healthcare Engineering and Bioinformatics, Systems Modeling and Simulation, Medical Sensors and Devices, Biomechanics, Multi-Scale Imaging, Systems Biology and Molecular Medicine, and Biomaterials and Regenerative Medicine.  exHIBITS

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exhibits Exhibits

Booths # 214 / 216

Booths # 532 / 534

The University of Texas at Austin

University of Texas at San Antonio

Department of Biomedical Engineering 107 W. Dean Keeton, C0800 Austin, TX 78712 Phone: 512-475-8623 Email: [email protected] Web: www.bme.utexas.edu

One UTSA Circle, AET 1.102 San Antonio, TX 78249 Phone: 210-458-7084 Email: [email protected] Web: http://engineering.utsa.edu/BME

The University of Texas at Austin’s Biomedical Engineering Department educates the next generation of biomedical engineers by offering B.S., M.S., and Ph.D. degrees.  Scholars and students build interdisciplinary knowledge in areas such as bioinformatics, biomechanics, biomedical imaging and instrumentation, cellular and biomolecular engineering, and computational biomedical engineering, among others.

The UTSA-UTHSCSA Joint Graduate Program in Biomedical Engineering provides a unique environment and state-of-the-art facilities for training of the next generation biomedical engineers, with academic tracks being offered based on segments of biomedical engineering and/or areas of clinical emphasis.  A truly joint graduate program administered by both UTSA and UTHSCSA, students are mentored by clinicians, engineers, and/or scientists and are trained to display an in-depth understanding of the concepts that are necessary for critically judging the scientific literature and innovation, for formulating novel hypotheses and/or designing experimental protocols, critically interpreting their results, and contributing to the biomedical field.

DISCOVER. INNOVATE. ACHIEVE. Graduate students in WPI’s Biomedical Engineering Department collaborate with scientists and engineers across disciplines, seeking breakthroughs in regenerative medicine, innovations in bioinstrumentation, and advances in healthcare. Graduates have gone on to rewarding careers at major medical and biomedical research centers across academia, government, and the medical device industry. Visit WPI’s table in the exhibit hall

wpi.edu/+gradbme

exHIBITS

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BMES 2014

exhibits

Booth # 437

Booth # 303

University of Toronto

University of Washington

Institute of Biomaterials & Biomedical Engineering Rosebrugh Building, 1645 College Street, Room 407 Toronto, Ontario M5S 3G9 Canada Phone: 416-946-8019 Email: [email protected] Web: www.ibbme.utoronto.ca

Department of Bioengineering 3720 15th Avenue NE Box 355061 Seattle, WA 98195 Phone: 206-685-2000 Email: [email protected] Web: http://depts.washington.edu/bioe/index.html

Collaboration shapes innovation at the University of Toronto’s Institute of Biomaterials & Biomedical Engineering (IBBME). Spanning three faculties (Applied Science & Engineering, Medicine and Dentistry) and ten major hospitals, IBBME’s unique biomedical and clinical engineering research programs deliver world-class, real world education for students of Canada’s top-ranked University.

Please visit the University of Washington at booth 303 to discover how we are inventing the future of medicine. Our faculty and students are eager to talk to you!

Booth #523

University of Utah Department of Bioengineering Scientific Computing & Imaging (SCI) Institute 3226 Sorenson Molecular Biotechnology Building (SMBB) 36 S. Wasatch Drive, Room 3226 Salt Lake City, UT 84112 Phone: 801-581-8528 Web: www.bioen.utah.edu and www.sci.utah.edu/ The Department of Bioengineering and the SCI Institute are internationally recognized for research in biomaterials, drug delivery, neuroengineering, othropedics, cardiovascular medicine, visualization, scientific computing, and image analysis, respectively. Together they offer BS, MS, and PhD training opportunities in a world class vacation destination located at the base of the Wasatch Range. The highly entrepreneurial and interdisciplinary environment is distinguished by its strong collaborative connections between clinical medicine, engineering and industry; a place where researchers can work and play hard. Booth # 109

University of Virginia Department of Biomedical Engineering P.O. Box 800759 Charlottesville,VA 22908 Phone: 434-924-5101 Email: [email protected] Web: http://bme.virginia.edu Join a vibrant network of engineers, clinicians, basic scientists and entrepreneurs.  U. Virginia Biomedical Engineering offers a rare blend of Engineering and Medicine, with an exceptionally supportive, collaborative training environment for translational research and the basic sciences.  UVA: Explore, Discover, Invent.

Booth # 108

Valtronic 29200 Fountain Pkwy Solon, OH 44139 Phone: 440-349-1239 Email: [email protected] Web: www.valtronic.com Booth # 210

Vanderbilt University Department of Biomedical Engineering VU Station B, Box 351631 Nashville, TN 37235 Phone: 615-343-1099 Email: [email protected] Web: engineering.vanderbilt.edu/BiomedicalEngineering.aspx VU BME bridges Vanderbilt’s engineering, basic science departments, and its renowned medical center; an ideal location for engineering research at the interface of technology and medicine.  Research strengths include image-based technologies, nanobiotechnology, biophotonics, modeling, biomaterials, bioregenerative engineering, bioMEMs.  VU BME stimulates high impact research and provides unique educational opportunities. Booth # 127

Virginia Commonwealth University 401 W. Main Street Richmond,VA 23284 Phone: 804-828-7956 Email: [email protected] Web: biomedical.engr.vcu.edu "Located on a thriving urban campus, VCU Biomedical Engineering has strong ties with the VCU Medical Center, School of Medicine, School of Dentistry, and Massey Cancer Center, and offers degrees at the Bachelor's, Master’s, and Doctoral level. Research specialties include mechanobiology, regenerative medicine, orthopaedic biomechanics, rehabilitation engineering, and biomaterials."

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exhibits

Booths # 200 / 202 / 204 / 201 / 203 / 205

Booth # 215

Virginia Tech-Wake Forest University

Whitaker International Program

School of Biomedical Engineering & Science VT-WFU SBES: 317 Kelly Hall (MC0298) Blacksburg,VA 24061 Phone: 540-231-8191 E-mail: [email protected] Web: www.sbes.vt.edu

809 United Nations Plaza New York, NY 10017 Phone: 212-984-5442 Email: [email protected] Web: www.whitaker.org

The Virginia Tech—Wake Forest University, School for Biomedical Engineering and Sciences offers MS, PhD, MD/PhD, and DVM/PhD degrees.  We have 76  biomedical engineering faculty with active research programs in tissue engineering, imaging, biomechanics, medical physics, nano-medicine, & nanobioengineering, neuroengineering,  translational oncology, cardiovascular engineering, and other emerging fields. Booth # 321

Washington University in St. Louis Department of Biomedical Engineering One Brookings Drive, Box 1097 St. Louis, MO 63130 Phone: 314-935-6164 Email: [email protected] Web: http://bme.wustl.edu/ In partnership with our world-class medical school, our department emphasizes interdisciplinary training from top-notch faculty. Our main research areas are biomaterials and tissue engineering; cardiovascular engineering; imaging; molecular, cell and systems engineering; and neural engineering. Our department has more than 75,000 sq. ft. of state-ofthe-art facilities. We offer BS, MS, MS/MBA, PhD and MD/PhD degrees. Booths # 314 / 316

Wayne State University 818 W. Hancock Detroit, MI 48201 Phone: 313-577-1345 Email: [email protected] Web: www.bme.wayne.edu The Biomedical Engineering Department at Wayne State University offers BS, MS, PhD and MD/PhD degrees. It is involved in some of the newest ground breaking research in the field. From the use of biomaterials to aid in the regeneration of nerves and the tailoring of these materials to optimize cellular response, to the use of advanced human modeling to study the biomechanics of impact injuries, and the study of sports related injuries and prevention of these injuries, Wayne State will play a major role in the development of new standards to better the quality of human life. Our past research has led to improvement in the standards of the automotive industry, better safer equipment for our soldiers, and a better understanding of injury biomechanics to help prevent and repair damage from these injuries.

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The Whitaker International Program provides funding to emerging U.S.based leaders in biomedical engineering, with a goal of building international bridges.  Grant projects – including research, coursework, public policy work – are intended to enhance both the recipient’s career and the BME field.  Administered by the Institute of International Education. Booth # 420

Worcester Polytechnic Institute 100 Institute Road Worcester, MA 01609 Phone: 508-831-5301 Email: [email protected] Web: www.wpi.edu/+gradbme Graduate students in WPI’s Biomedical Engineering (BME) Department collaborate with scientists and engineers across disciplines, seeking breakthroughs in regenerative medicine, innovations in bioinstrumentation, and major steps forward in healthcare. Whether in the classroom or the lab, the focus remains squarely on solving real-world problems. BME graduates have gone on to rewarding careers at major medical and biomedical research centers across academia, government, and the medical device industry. Booth # 234

Yale University Biomedical Engineering 55 Prospect Street New Haven, CT 06511 Phone: 203-432-4262 Email: [email protected] Web: www.seas.yale.edu/bme The booth will be staffed with graduate representatives and faculty from the department of Biomedical Engineering at Yale. The faculty and graduate representative will aim to describe the program to interested visitors and answer any questions regarding the program requirements and admissions process.

S O M E T H I N G

N E W w w w. s b e s . v t . e d u

General Information & presenter information

Meeting Location Henry B. Gonzales Convention Center 200 East Market Street

BMES Presenter Information Platform Presentations Each technical session room will be equipped with a PC-compatible

San Antonio, TX 78205

computer with a USB port and PowerPoint along with an LCD projec-

(210) 207-8500

tor, screen and a lectern with microphone.

Marriott Rivercenter | co-headquarters 101 Bowie Street

During the half hour before your session begins, please upload your presentation onto the computer using a memory stick or flash drive.

San Antonio, TX 78205

Because of the potential difficulty transferring some Mac files to PC

(210) 223-1000

format, we encourage you to avoid use of animation if there is a

Marriott Riverwalk | co-headquarters 889 East Market Street

question about transferability. Please do not try to connect your own laptop. Please note, it will not

San Antonio, TX 78205

be possible to provide special equipment. Any additional equipment

(210) 224-4555

will need to be supported by the presenter. Although BMES has paid for WiFi throughout the convention center during the Annual Meet-

Registration

ing, there will not be specific dedicated hard-wired internet access in

Paid registration is required for admission to all meeting functions

the meeting rooms.

including scientific sessions, posters, exhibits, breaks and the BMES BASH at the Buckhorn Saloon & Museum. BMES cancellation policy may be found on any registration form. Any applicable refunds will be issued post-meeting. Substitutions are permitted with written permission from the original registrant. Additional social event tickets including the Celebration of Minorities in BME Luncheon, and the Women in BME Luncheon are separate and above BMES meeting registration.

Sessions chairs should keep sessions on the listed schedule so attendees can move back and forth among sessions. In most cases, presentations should be done in twelve minutes, allowing three minutes for questions and answers and transition to the next speaker.

Poster Presentations Posters will be presented Thursday, Friday and Saturday. Posters are to be displayed all day on assigned day. Authors must be present dur-

On-Site Registration Hours

ing specified viewing with authors as listed in Scientific Program: Thursday

9:30-10:30am and 3:30-4:30pm

Friday

9:30-10:30am and 4-5pm

7:00am – 6:00pm

Saturday

9:30-10:30am

7:00am – 2:00pm

All posters will be in the Exhibit Hall A in the Henry B. Gonzales Con-

Wednesday, October 22

11:00am – 7:00pm

Thursday, October 23

7:00am – 6:00pm

Friday, October 24 Saturday, October 25

vention Center. Posters are numbered with a card corresponding to the numbers assigned in the program.

Exhibits Exhibit Hall A, Henry B. Gonzales Convention Center Exhibits are located in the Exhibit Hall A in the Henry B. Gonzales Convention Center. Exhibits will be open: Thursday, October 23

9:30am – 5:00pm

Friday, October 24

9:30am – 5:00pm

Saturday, October 25

9:30am – 1:30pm

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BMES 2014

Speaker Ready Room Registration Area, Exhibit Hall A, Henry B. Gonzales Convention Center In the BMES Speaker Ready Room you will find cables, LCD projector and screen to practice your presentation. Please bring your own laptop. Wednesday, October 22

11:00am – 5:00pm

Thursday, October 23

7:00am – 5:00pm

Friday, October 24

7:00am – 5:00pm

Saturday, October 25

7:00am – 2:30pm

Program Highlights

Program Highlights Don’t Miss These Events WEDNESDAY, October 22

Meet the Faculty Candidate Forum 3:30pm - 5:30pm West Registration Hall, Henry B. Gonzales Convention Center The "Meet-the-Faculty Candidate" poster session provides a great opportunity for faculty, recruiters, and Department Chairs to speak directly with current graduate students and postdoctoral researchers who are seeking faculty positions. The BMES 2014 Annual Meeting MEET THE FACULTY CANDIDATE FORUM was only open to those who are actively on the market for the 2014-2015 recruiting cycle. Candidates submitted for consideration in August. The accepted candidates' CVs can be viewed at www.bmes.org. WEDNESDAY, October 22

Welcome Reception 5:30pm - 7:00pm Grotto, River Level, Henry B Gonzales Convention Center Light refreshments will be served. All registrants are invited to attend. THURSDAY, October 23

BMES State of the Society Address & Fellows Induction 10:30am Lila Cockrell Theatre, Henry B. Gonzales Convention Center

FRIDAY, October 24

BMES Bash at Buckhorn Saloon & Texas Rangers Museum 7:00pm - 10:00pm 318 E. Houston Street San Antonio TX 78205 (210) 247-4000 The Buckhorn Museum features wildlife specimens from all over the world; including fish from the seven seas, animals from every

Please join us for a dialogue with BMES President Gilda Barabino and

continent and strange animal oddities which have been collected for

other leaders of the Society.

over 100 years! The exhibit halls are comprised of over 520 species of wildlife—many of which are record holders. Look for your school's mascot. The school posting the largest number of Twitter pictures with their mascot will win a prize.

Refreshment Breaks

Connected to the Buckhorn, The Texas Ranger Museum features

Please note your meeting registration includes morning and

hundreds of authentic Texas Ranger artifacts including automatic

afternoon refreshments breaks on Thursday, Friday and

handguns, shotguns, badges and more. The museum also features a

Saturday. All refreshment breaks will be in the Exhibit Hall.

recreation of San Antonio at the turn of the century in Ranger Town.

Thursday afternoon refreshment break sponsored by

and a replica of the 1934 Ford V8 Deluxe—the famous Bonnie &

The town includes a replica Buckhorn Saloon, a jail cell, blacksmith Clyde getaway car. Shuttle buses will run continuously from 6:30pm -10:00pm

Friday afternoon refreshment break sponsored by

between the Marriott Rivercenter and the BMES Bash. Buses will be staged at the Commerce Street exit of the hotel.

BMES 2014

51

luncheons

THURSDAY, October 23

FRIDAY, October 24

Celebration of Minorities in BME Luncheon*

Women in BME Luncheon*

12:30-1:45pm

Ballroom A, Henry B. Gonzales Convention Center

Ballroom A, Henry B. Gonzales Convention Center *additional registration and $25 ticket required

This is the fifth year of this event hosted by the BMES Diversity Committee to create a community and network within the Society fostering support and professional development of minorities in BMES at all levels. Everyone is invited to attend, as diversity only

12:15pm - 1:30pm *additional registration and $25 ticket required

Speakers: “Innovations and the Road to Commercialization” Zoraida P. Aguilar, PhD, MS, CTO/President, Zystein, LLC "Trading Tenure for Translation"

increases when all groups play a part. The luncheon complements

Kevin D. Nelson, PhD, Founder & CSO TissueGen, Inc.

the Diversity Award lecture on Saturday and the Women in BME

Additional Panelists:

Luncheon on Friday.

Subashini Asokan, PhD, Technology Licensing Associate, The

This year's lead speaker is Provost Lisa Firmin. Provost Firmin is the

University of Texas at San Antonio

Associate Provost for Faculty and Student Diversity and Recruitment

Athanassios Sambanis, PhD, Program Director, Biomedical En-

at The University of Texas at San Antonio. In this role, she coordi-

gineering Chemical, Bioengineering, Environmental, and Transport

nates efforts between Academic and Student Affairs to attract a high

Systems Division, National Science Foundation

quality, diverse student population. Additionally, she works at the

Professor, School of Chemical & Biomolecular Engineering, Georgia

strategic level to address faculty diversity and placement goals.

Institute of Technology Translation is within Your Reach Too often our individual or team successes are summarized in publications and fail to reach the community we hope to impact. At this luncheon, we will showcase two outstanding scientists, Drs. Aguilar and Nelson, who embraced opportunities in entrepreneurship. They will share key lessons in fundraising, product development, and business planning. Drs. Asokan and Sambanis will answer questions on technology licensing and federal funding opportunities. Translating your next big idea may not be as far off as you think. Come meet the speakers and ask questions about your next step towards translation. Women in BMES activities have made a visible impact at the meeting, creating a forum for exchange across disciplines, between industry and academia, and between senior leaders in the field and junior faculty, trainees, and students. Women in BME Luncheon Sponsored by

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BMES 2014

Additional Meetings

Additional Meetings Wednesday, October 22 BMES Board of Directors Meeting

BMES Membership Committee Meeting 1:30pm - 2:30pm Convention Center, Room 003A

Organizer: Jennifer Edwards

8:30am – 4:30pm Convention Center, Room 102 AB

Friday, October 24

Organizer: Gilda Barabino

2015 BMES Annual Meeting Committee Meeting

AIMBE Board of Directors Meeting 11:00am - 4:00pm Convention Center, Room 003AB

Organizer: Milan Yager AIMBE Council Meeting 3:00pm – 4:00pm Convention Center, Room 003AB

Organizer: Milan Yager Annals of Biomedical Engineering - Editorial Board 7:00pm - 10:00pm Marriott Rivercenter, Conference Rooms 13/14

Organizer: Christina Dzikowski Council of Chair Dinner & Meeting 6:15pm - 9:00pm Marriott Rivercenter, Room

Organizer: John Troy

Thursday, October 23 BMES National Meetings Committee Meeting 7:00am - 8:00am Convention Center, Room 003A

7:00am - 8:00am Convention Center, Room 003A

Organizer: Steve George ABioM SIG Business Meeting 7:00am - 8:00am Convention Center, Room 102AB

Organizer: Kaiming Ye BMES Education Committee 7:00am - 8:00am Convention Center, Room 003B

Organizer: Michele Ciapa CMBE SIG Business Meeting 12:00noon - 1:30pm Convention Center, Room 003B

Organizer: Cheng Dong BMES International Affairs Committee Meeting 1:30pm - 2:30pm Convention Center, Room 003A

Organizer: Jennifer Edwards BMES Industry Affairs Committee Meeting

Organizer: Christine Schmidt

4:00pm - 5:00pm

BMES Diversity Committee Meeting

Organizer: Jennifer Edwards

Convention Center, Room 003A

7:00am - 8:00am Convention Center, Room 003B

Organizer: Michele Ciapa Cellular and Molecular Bioengineering – Editorial Board 12noon – 1:30pm Marriott Rivercenter, Conference Rooms 13/14

Organizer: Christina Dzikowski Medical Devices SIG Business Meeting 12:45pm – 1:45pm Convention Center, Room 003A

Saturday, October 25 BMES Student Affairs Committee Meeting 12:30pm - 1:30pm Convention Center, Room 003A

Organizer: Elizabeth DaSilva BMES Board of Directors Meeting & New Board Orientation 1:00pm - 3:30pm Convention Center, Room 102AB

Organizer: Rich Hart

Organizer: Leticia Marquez

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hosted receptions

Hosted Receptions Marriott Rivercenter and Marriott Riverwalk Thursday, October 23 Individual organizations have set their own times for their private receptions. Please consult your invitation for the specific time. Generally receptions are from 8:00-9:30pm.

Arizona State University Travis Room, Marriott Marriott Riverwalk Biomedical Engineering Opportunities in India Alamo F, Marriott Riverwalk Clemson University Conference Room Rm 11, Marriott Rivercenter Cornell University Alamo C, Marriott Riverwalk Duke University Conference Room Rm 12, Marriott Rivercenter Florida International University Conference Room 15, Marriott Rivercenter

Rice University Salon D, Marriott Rivercenter

University of Southern California Alamo A, Marriott Riverwalk

University of Akron Conference Room Rm 1, Marriott Rivercenter

University of Texas Austin Salon E, Marriott Rivercenter

University of California Berkeley Conference Room Rm 17, Marriott Rivercenter

University of Texas at San Antonio Atrium, Marriott Rivercenter

University of California Irvine Alamo E, Marriott Riverwalk

University of Utah Conference Room Rm 8, Marriott Rivercenter

University of California Los Angeles Conference Room Rm 7. Marriott Rivercenter

University of Virginia Conference Room Rm 5, Marriott Rivercenter

University of California, San Diego Conference Room Rm 18, Marriott Rivercenter University of Illinois at Chicago Conference Room, Rm 2 Marriott Rivercenter University of Illinois at Urbana-Champaign Salon J, Marriott Rivercenter

Georgia Institute of Technology Salon KL, Marriott Rivercenter

University of Pennsylvania Conference Room Rm 13-14, Marriott Rivercenter

Johns Hopkins University Salon C, Marriott Rivercenter

University of Pittsburgh Conference Room Rm 3-4, Marriott Rivercenter

Rensselaer Polytechnic Institute Alamo D, Marriott Riverwalk

University of Rochester Alamo B, Marriott Riverwalk

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BMES 2014

University of Washington Salon I, Marriott Rivercenter University of Wisconsin Madison Salon B, Marriott Rivercenter Vanderbilt University Riverview, Marriott Riverwalk Whitaker International Reception Conference Room 16, Marriott Rivercenter

Save the dates! 2015 Biomedical Engineering Career Conferences

WBECC 2015

SEBECC 2015

UC San Diego - La Jolla, CA Spring 2015

Durham Convention Center - Durham, NC Friday, October 23, 2015

Western Biomedical Engineering Career Conference

Southeast Biomedical Engineering Career Conference

Attend the 2015 BME career conferences to: ➤ Learn about BME Career opportunities ➤ Network with employers and students/alumni of BME programs in and around the region ➤ Showcase ongoing research at BME programs ➤ Present your poster abstract ➤ Tour a BME department ➤ Get advice from experienced professionals on how to advance your career ➤ Have your resume reviewed, critiqued and edited For more information and updates: www.bmes.org/careerevents/ [email protected] Or call: (301) 459-1999

Career Connections is a career development resource of:

BIOMEDICAL ENGINEERING SOCIETY Advancing Human Health and Well-BeingTM

www.bmes.org

TM

Student & early career programs

career and professional development sessions The career and professional development sessions offer career guidance for job seekers ranging from entry level to experienced professionals. The sessions will highlight both traditional and alternative careers available to BMEs. Thursday, October 23

What Do Biomedical Engineers Actually Do? What Are the Specialization Areas? 9:00am - 10:30am Convention Center, Room 103A

This session will begin with the facilitator describing what a biomedical engineer is; what they do, where they work, what positions they hold, what projects they work on, and what their career prospects are. Our panelists who have backgrounds in various specialty areas will share their educational backgrounds, career pathways, detailed experiences, and insights. In addition, you will have an opportunity to ask our panelists questions to help guide you on your own career path. At the end of this session, you will have a clearer understanding of what biomedical engineers actually do and possibly even know how you'll fit in.

How to Get Your First Job

1:30pm - 2:45pm Convention Center, Room 103A Whether you are searching for your first job or you're a young professional eager for a change, this session will show you the RIGHT way to job search. Avoid the mistakes and excuses that sabotage your chance to WIN a job in today's competitive market. Are you sending out tons of résumés and getting no responses? Are you worried about interviewing? Fasten

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your seatbelts for an instructional session from a career coach and ex-Microsoft hiring manager! You will leave this session with the skills you need to conduct your job search more effectively and land that job sooner. sponsored by

Networking Effectively —Social Media & Face-to-Face 3:15pm – 4:30pm Convention Center, Room 103A

Do you feel awkward about networking? Do you just want to hide in the corner at events? Are you nervous about contacting a senior professional you don’t know via LinkedIn? Ever been tongue-tied trying to describe what type of job you are looking for? Ever wonder how best to sell yourself to someone who doesn’t understand biomedical engineering? You’re not alone. Fifty percent of the world is made up of introverts! Because networking is a requirement for getting and excelling in a job today, this workshop will guide you through the steps to face networking head-on. You will leave this session with the skills to connect with total strangers, make an impact, and get the results you are hoping for. You will also gain an understanding of when and how to use social media, email, and the telephone for networking.

Resume Review and Critique Have your resume reviewed and critiqued by career professionals and take away writing tips.

Thursday, October 23 2:00pm - 4:00pm Friday, October 24 2:00pm - 4:00pm Convention Center, Room Room 102AB

Mock Interview Demonstration

5:00pm – 6:15pm Convention Center, Room 103A If you don’t ace the interview, you won’t get the job! It’s way more than just making a good first impression. As with every skill you've ever learned, you have to learn the techniques and then prepare, prepare, prepare. Sure, there are books and YouTube videos on interviewing, but this high-energy session is interactive and you will see firsthand what happens in a great interview (and a not-so-great interview). Seeing it live will help you perfect your technique while getting the coaching you need. Learn what interviewers are looking for, the dos and don’ts, what defines a strong candidate, and how to prepare for an interview. Come and get a powerful handout you will use again and again!

Student & early career programs STUDENT CHAPTER TABLES Friday, October 24

Stop by the Student Chapter Booths inside the Registration area in Exhibit Hall A to see what's going

BMES Student Chapter Outstanding Chapter Best Practices

on "on campus"!

Cornell University

8:30am – 9:30am Convention Center, Room 103A

LeTourneau University

This workshop will feature the BMES Student Chapter from San José State University (awarded the BMES Outstanding Student Chapter Award), along with the BMES Student Chapter from The Ohio State University (awarded the Commendable Achievement Award). The workshop will provide information on chapter best-practices, allowing students to ask questions, exchange ideas and implement goals for the upcoming year.

Louisiana Tech University

BMES Student Chapter— Outreach and Mentoring Best Practices

University of Illinois at Urbana-Champaign

Purdue University San Jose State University Stony Brook University University of California, Davis

University of North Carolina, Chapel Hill

9:30am - 10:30am Convention Center, Room 103A

University of Tennessee – Knoxville

This workshop will feature the BMES Student Chapter from the University of California, Davis (awarded the BMES Outstanding Mentoring Award) and the BMES Student Chapter from the University of Pennsylvania (awarded the BMES Outstanding Outreach Award). The workshop will provide information on chapter best-practices, allowing students to ask questions, exchange ideas and implement goals for the upcoming year.

University of Texas, Austin University of Wisconsin – Madison Vanderbilt University Virginia Commonwealth University Virginia Tech/Wake Forest University

Owning Your Career & Using Mentors 1:30pm - 2:30pm Convention Center, Room 103A

Take control of your career! Whether you are employed or searching for a job, this session will provide a structured “roadmap” to help you develop and execute a short-term career plan. Learn actionpacked steps to get started with and apply a new approach throughout your career. In addition, this session will teach you how to build a mentorship base. Who should your mentors be? Learn your role as the “mentee” and what to expect from your mentors. These are tips you will be able to implement successfully right away. Remember: nobody cares about your career more than you do; you owe it to yourself to learn new ways to get ahead!

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Register Today! www.bmes.org/MBECC14registration

Biomedical Engineering Society

2014 Midwest Biomedical Engineering Career Conference Hosted by Wayne State College of Engineering

November 7, 2014

McGregor Conference Center Detroit, MI

Visit the 2014 MBECC website at www.bmes.org/MBECC14 • More information about the conference • A full list of activities • Sponsorship and exhibit opportunities

Career Connections is a career development resource of:

BIOMEDICAL ENGINEERING SOCIETY Advancing Human Health and Well-BeingTM

www.bmes.org

TM

➤ Have your resume reviewed, critiqued and edited ➤ Be mentored by practicing bioengineers ➤ Hear how to improve your BMES student chapter ➤ NETWORK ➤ Topics covered: • Biomedical Industry Careers • Clinical and Academic Careers • Alternative Careers • Marketing Yourself for Your First Job • BME Entrepreneurship and Translational Research • Bridging Research to Career: Safety and Injury Biomechanics • Bridging Research to Career: Imaging and Image Analysis • Bridging Research to Career:

Tissue Engineering/Nanotechnology

Student & early career programs – AEMB

Alpha Eta Mu Beta (AEMB) Programs Alpha Eta Mu Beta Annual Grand Meeting

testing have always involved the types of tissues or cells used. Selfregulated oversights have been provided at institutions to ensure compliance of the US federal law and to oversee animal care and use within the institutions. As funding is also shifting from federal agencies to the biomedical industries, other potential ethical con-

Thursday, October 23

cerns have also emerged, including conflict of interest between the

4:00pm - 5:30pm Convention Center, Room 002AB

industry and the researchers. These conflicts are often managed by

Session Co-chairs: Dominic E. Nathan PhD, Rupak Dua, PhD, Stephanie Naufel, MS, Rachel Hanks, BS, Rafeed Chaudhury, BS, Marcia A. Pool, PhD and Anthony McGoron PhD.

ers are aware of the moral and ethical concerns prior to embarking

At this annual grand meeting, members representing chapters na-

Alpha Eta Mu Beta (AEMB), the National Biomedical Engineering

tionwide will come together to discuss important contemporary

Honor Society, is committed to promoting ethics in the field of bio-

events relating to AEMB. (Attendance is mandatory for all AEMB

medical engineering. This year, AEMB is honored to host Anson Joo

members). This year we will be holding national elections. If you

L. Ong, Ph.D. is currently the USAA Distinguished Professor and

would like to learn more about AEMB or start a new chapter at your

Chairman for the Department of Biomedical Engineering at the Uni-

school, please consider attending this session and speaking to any

versity of Texas at San Antonio. He is also the Program Director for

of the national officers.

the Joint Graduate Program in Biomedical Engineering as well as an

Alpha Eta Mu Beta Reception (Invitation Only) Thursday, October 23

the investigator's institution. As such, it is imperative that researchon their experimental designs.

Adjunct Professor in the Department of Comprehensive Dentistry at the University of Texas Health Science Center at San Antonio. Aside from his current academic appointments, Dr. Ong is also the Associate Editor for the Journal of Biomedical Materials Research, Part

6:00pm - 8:00pm The Annual AEMB reception will be held at The Republic of Texas Restaurant (429 E Commerce St San Antonio, TX 78205).

B. He received his bachelor's degree from the University of Iowa

Session Co-chairs: Rupak Dua, MS, Rafeed Chaudhury, BS, Stephanie Naufel, MS, Rachel Hanks, BS, Marcia Pool, PhD and Dominic E. Nathan, PhD.

characterization of the implant biomaterials surfaces for dental and

We will be presenting the national awards and charters for new chapters during this session. Furthermore, this session is a networking opportunity to meet with other fellow members from AEMB chapters, representatives from industry and academia. This session is open to all AEMB student and faculty members, however tickets are required. For tickets, please contact [email protected] .

Ethics in Tissue-Biomaterials Engineering (Annual Alpha Eta Mu Beta Ethics Session)

in 1987, and his M.S. and Ph.D. from the University of Alabama at Birmingham in 1990 and 1994, respectively. Dr. Ong's primary research interests focus the modification and orthopedic applications, modification of tissue engineered ceramic scaffolds, protein-biomaterials interactions, and bone-biomaterials interactions. His work has been funded by the National Institute of Health, National Science Foundation, the Whitaker Foundation, Implant Dentistry Research and Education Foundation, Academy of Prosthodontics, American Association for Dental Research, and US Army, as well as numerous biomedical industries. Dr. Ong has authored/co-authored over 100 articles published in refereed journals and over 200 conference abstracts. In addition, he has given invited lectures and keynote lectures at national and international meetings, served as a manuscript reviewer for several biomedical engineering

Friday, October 24

related scientific journals, and continues to serve as a grant reviewer

9:00am - 10:00am Convention Center, Room 002AB

for the National Institutes of Health, National Science Foundations,

Session Chairs: Anson Joo L. Ong, PhD and Rupak Dua, PhD

Dr. Ong has served on numerous committees in professional societ-

Tissue-biomaterials interactions have always been in the mind of

ies, including the Society for Biomaterials, Biomedical Engineering

researchers when focusing on developing or modifying biomateri-

Society, and the International Association for Dental Research. He is

als and tissue engineering constructs for optimal properties. These

currently on the editorial board of several biomedical related journals

newly developed or modified materials are often evaluated in cell

and was the Past Program Chair for the Society for Biomaterials and

culture systems or in animal models. As a result, ethical issues re-

the Past President of the Implantology Research Group in the Inter-

lated to biomaterials and tissue engineering research needs to be

national Association for Dental Research.

Department of Defense, and other international funding agencies.

considered during their testing phase. Ethical concerns in pre-clinical

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59

Student & early career programs - AEMB/Whitaker Understanding Why Congress Doesn't Fund Research Friday, October 24 1:30pm - 3:00pm Convention Center, Room 002AB

Whitaker International Program: Funding Opportunity for Young Biomedical Engineers Friday, October 24

Session Chair: Teresa Murray, PhD

8:00am - 9:30am Convention Center, Room 204A

How will sequestration budget cuts impact the biomedical In halls of

The Whitaker International Program, founded in 2005 provides

Congress. Widespread agreement exists about the role of R&D in

funding to emerging U.S.-based leaders in biomedical engineering

the success of the America's most innovative corporations. Howev-

to conduct a study and/or research project, with the underlying ob-

er, many view government models of discovery from NASA to public

jective of building international bridges. Grant projects—including

university research labs as obsolete and costly superstructures in

research, coursework, and public policy work—are intended to en-

today's dot com marketplace. What happened to the case for public

hance both the recipient’s public career and the BME field. The goal

exploration and discovery and why shouldn't the private sector be

of the Whitaker Program is to assist the development of professional

trusted to find the cure for Grandma's dementia or Mark's brain tu-

leaders who are not only superb scientists, but who will advance

mor? Long-time Washington political insider, former lobbyist, Admin-

the profession through an international outlook. The Whitaker Pro-

istration appointee, and AIMBE's Executive Director, Milan Yager, will

gram has three sub-programs: Fellows and Scholars Program, Sum-

reveal the hidden truth about why Congress doesn't fund needed

mer Program, and an Undergraduate Program. For more informa-

medical research. Discover three secrets to making a winning case

tion, including program details, the online application and deadlines,

for federal funding for medical and biological research. Learn practi-

visit: http://www.whitaker.org.

cal steps to successfully getting your point across to a member of Congress. Find out how to brand your university lab as a leader in the race to cure cancer, reduce obesity, or manage chronic disease. Arm yourself with the strategies for changing the policy landscape; it might provide the key to funding for your next discovery. This session features a panel of experts who routinely communicate with Congress, anchored by Milan Yager, Executive Director, American Institute for Medical and Biological Engineering. We will have a lively, moderated discussion after the panelists' presentations. We particularly encourage students and early career members to participate, but all are welcome to attend. AIMBE represents the top 2% of medical and biological engineers from industry, government, universities and clinical practice. AIMBE is the leading voice for public policy supporting medical and biological engineering innovation to improve public health. AIMBE staff and fellows regularly meet with key administration officials, Congress, and

1. Sabeen Altaf (Session Chair) Senior Program Manager, Science and Technology Programs Institute of International Education 2. Sandra Baker Whitaker International Fellow, 2013-14 Host Institution: Institute of Bioengineering of Catalonia Title: Development of a multi-photon microscopy system for measuring traction forces during in vivo aniogenesis 3. David Bradway Whitaker International Scholar, 2012-13 Host Institution: Technical University of Denmark Title: Cardiovascular velocity vector imaging: real-time processing and pre-clinical trials 4. Cassandra Harn

monitor trends in public policy impacting the field. AEMB members

Whitaker International Fellow, 2012-13

represent the top BME students across the US. Starting in 2006, we

Host Institution: Bionnovate Ireland

have sponsored the Student Ethics Session training future BMEs to

Title: An opportunity in innovation training in medical

evaluate the broader impacts of emerging biomedical innovations.

device development and how it has directed my future

Last year, we initiated the first student public policy session at BMES with our co-sponsor, AIMBE.

5. Samantha Paulsen Whitaker International Fellow, 2012-13 Host Institution: ETH Zurich Title: Optimizing bioreactor and blood vessel geometries for improved mass transport using computational fluid dynamics 6. Justine Roberts Whitaker International Scholar, 2013-14 Host Institution: University of New South Wales Title: The design of bio-synthetic, heparin-poly

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(vinyl alcohol) hydrogels for wound healing applications

Whitaker International Program: Fellows, Scholars & Summer Programs

Type of Awards: Fellows Award: one year award after receiving your bachelor’s degree. Scholars Award: for post-doctoral work. Summer Award: for BME coursework or research towards your Master’s or Ph.D. degree.

Congratulates  the  2014  CMBE  Young  Innovators!   September  2014  issue,  edited  by  David  Mooney,  Cynthia  Reinhart-­‐King  and  David  Schaffer  

Lauren  Black        TuYs  U.   Adam  Feinberg        Carnegie  Mellon   Tom  Gaborski        Rochester  Inst.                  Tech.   Pamela  Kreeger        U.  Wisconsin   Jan  Lammerding        Cornell  U.   Allen  Liu        U.  Michigan   David  Merryman        Vanderbilt  U.  

Kathryn  Miller-­‐ Jensen        Yale  U.   Keith  Neeves        Colorado  School          of  Mines   Krishanu  Saha        U.  Wisconsin   Ankur  Singh        Cornell  U.   Junghae  Suh        Rice  U.   Hossein  Tavana        U.  Akron  

See  the  Young  Innovators  present  their  work  on  Sat.,  October  25,  2014   •  Become  a  2015  CMBE  Young  Innovator!    Next  compeIIon  is  underway.   •  Accepted  authors  will  be  invited  to  present  their  work  in  a  special  two-­‐ part  plaOorm  session  at  the  2015  BMES  Annual  MeeIng.   •  To  be  eligible,  candidates  must  be  BMES  members  and  hold  a  posiIon  at   the  Assistant  Professor  level  or  equivalent.   •  Self  nominaIons  should  include  manuscript  Itle  with  200-­‐word  abstract,   and  a  2-­‐page  NIH-­‐style  biosketch,  emailed  to  [email protected]   Key  Dates  for  2015  Young  Innovators  issue:   NominaIon  Deadline:  November  15,  2014   Abstract  Acceptance:  December  15,  2014   Manuscript  Submission:  February  15,  2015   Print  PublicaIon:  September  2015    

2014 BMES Awards Recipients

2014 Awards Recipients

BMES Extended Abstracts: Design and Research Awards:

One of the more important — and most enjoyable — tasks of

Graduate Students

the Society is to recognize contributions to the intellectual and

Lauren Barney

professional development of the field of biomedical engineering. On behalf of the awards committee we would like to thank all the members who submitted nominations and provided letters of support and for the high quality of their nominees. Congratulations to the following award winners.

Robert A. Pritkzer Distinguished Award Lecture James Collins, PhD Boston University

NIBIB Lecture

University of Massachusetts, Amherst

Justin Lo Massachusetts Institute of Technology

Yekaterina Miroshnikova University of California San Francisco

Fatemeh Mokhtari Wake Forest University

Andrew Warren Massachusetts Institute of Technology

David Kaplan, PhD Tufts University

Rita Schaffer Young Investigator Award Lecture Kimberly Stroka, PhD

Undergraduate Students Gregory Danchik Bucknell University

Johns Hopkins University

Daniel Greenshields

Diversity Award Lecture Naomi Chesler, PhD University of Wisconsin-Madison

Lawrence Technological University

Malvi Hemani Johns Hopkins University

Annals of Biomedical Engineering (ABME) Awards Most Downloaded Article Ann Biomed Eng. 2013 May;41(5):873-82. doi: 10.1007/s10439-012-0731-0

Veronica Ibarra Illinois Institute of Technology

Brain Injury Prediction: Assessing the Combined Probability of Concussion Using Linear and Rotational Head Acceleration Steven Rowson, Stefan Duma

Rene Olivares-Navarrete

Most Cited Article

Virginia Commonwealth University

Ann Biomed Eng. 2013 Jan;41(1):68-77. doi: 10.1007/s10439-012-0630-4

Cationic Nanoparticles have Superior Transvascular Flux into Solid Tumors: Insights from a Mathematical Model Triantafyllos Stylianopoulos, Konstantinos Soteriou, Dai Fukumura, Rakesh K. Jain

Virginia Commonwealth University

Gireesh Reddy

Simone Siegel The University of Texas at Austin

BMES Student Chapter Awards 2014 Outstanding Achievement Award BMES Student Chapter at San Jose State University

2014 Commendable Achievement Award BMES Student Chapter at the Ohio State University

2014 Outreach Program Award BMES Student Chapter at University of Pennsylvania

2014 Outstanding Mentoring Award BMES Student Chapter at University of California, Davis

2013 Fleetest Feet Award BMES Student Chapter - Virginia Tech/Wake Forest University 53 Students – 117,580 Miles

BMES 2014

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2014 Track Chairs

Bioinformatics and Systems Biology

Cellular and Molecular Bioengineering

Kevin Janes

Chris Jacobs

University of Virginia

Columbia University

Kristen Naegle

Deborah Leckband

Washington University

University of Illinois

Melody Swartz

Biomaterials

Ecole Polytechnique Federale de Lausanne

Rebecca Carrier

Device Technologies and Biomedical Robotics

Northeastern University

Elizabeth Cosgriff-Hernandez Texas A&M University

Tamara Baynham Ingenuity Medical Device Res

Biomechanics Alesha Castillo Stanford University

Jonathan Vande Geest University of Arizona

Beth Winkelstein University of Pennsylvania

Mike McShane Texas A&M University

Drug Delivery Debra Auguste City College of New York, CUNY

Lola Eniola-Adefeso University of Michigan

Biomedical Engineering Education Matt Glucksberg Northwestern University

Ann Saterbak Rice University

Nano to Micro Technologies

Purdue University

City College of New York, CUNY

Christine Schmidt

Cancer Technologies

University of Florida

Cynthia Reinhart-King

New Frontiers and Special Topics Tejal Desai UC San Francisco

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BMES 2014

Samir Ghadial Ohio State University

Stem Cell Engineering Steven George UC Irvine

Shyni Varghese UC San Diego

Tissue Engineering Edward Botchwey Georgia Institute of Technology

Cytograft

University of Pennsylvania

University of Toronto

University of Pittsburgh

Nicolas L'Heureux

Kevin Otto

Milica Radisic

William Federspiel

University of Texas

Andrew Tsourkas

Stony Brook University

Respiratory Bioengineering

Duke University

Neural Engineering

Danny Bluestein

University of Utah

James Tunnell

University of Michigan

Cardiovascular Engineering

Jeff Weiss

Nenad Bursac

Doug Noll

University of Florida

Northwestern University

Boston University

Maribel Vazquez

Carlos Rinald

Wendy Murray

Catherine Klapperich

Biomedical Imaging and Optics

Cornell University

Orthopedic and Rehabilitation Engineering

Ranu Jung Florida International University -

Translational Biomedical Engineering Eben Alsberg Case Western Reserve University

Joyce Wong Boston University

Undergraduate Research (REU) William Guilford University of Virginia

Kristine Ropella Marquette University

Abstract Reviewers

Thank you to our reviewers for their time and effort: BIOINFORMATICS, COMPUTATIONAL AND SYSTEMS BIOLOGY Amy Brock Benjamin Cosgrove Michael Fenn Stacey Finley Heather Hayenga Princess Imoukhuede Kevin Janes Kyung Kim Tamara Kinzer-Ursem Kathryn Miller-Jensen Kristen Naegle Sriram Neelamegham Joseph Palladino Jason Papin Shayn Peirce Jeff Saucerman Cheemeng Tan Jun Wang

BIOMATERIALS Jorge Almodovar Natalie Artzi Gary Bowlin Jeffrey Capadona Hao Cheng Beata Chertok Youngjae Chun Tzahi Cohen-Karni Michael Davis Cole DeForest Meng Deng Erik Dreaden Craig Duvall Adam Ekenseair Lindsay Fitzpatrick John Frampton Akhilesh Gaharwar Gargi Ghosh Ryan Gilbert Anjelica Gonzalez Jordan Green Mariah Hahn Michael Heffernan Rebecca Heise Gregory Hudalla Jeffrey Jacot Christopher Jewell Srivatsan Kidambi Matt Kipper Joydip Kundu Elizabeth Loboa Hongyan Ma Ashwin Nair George Pins Smitha Rao

Michael Regnier Jai Rudra Alisha Sarang-Sieminski Vassilios Sikavitsas Agneta Simionescu Dan Simionescu Wei Tan Joe Tien Mark Van Dyke Scott Verbridge Yun Wang Jeff Wolchok Janet Zoldan

BIOMECHANICS Animesh Agarwal Taby Ahsan B. Rita Alevriadou Kyle Allen Yahia Al-Smadi Natalie Artzi Aaron Baker Janet Barzilla Lauren Black III Joel Boerckel Joel D Bumgardner Hung Cao Alesha Castillo Hao Cheng Tzahi Cohen-Karni John Cotton Jennifer Currey Eric Darling Rafael Davalos Michael Davis Cole DeForest Meng Deng Jaydip Desai Zachary Dooley Stefan Duma Eno Ebong Vittoria Flamini Akhilesh Gaharwar F. Scott Gayzik Craig Goergen Esther Gomez Anjelica Gonzalez Teja Guda Heather Hayenga Heath Henninger Yi Hong Marc Horner Roland Kaunas Mehmet Kaya Spencer Lake Christopher Lemmon Amy Lerner Jun Liao Alan Litsky Elizabeth Loboa

David Long Arash Mahboobin Robert Mauck Stuart Mitchell Jiro Nagatomi Jin Nam Sriram Neelamegham Keith Neeves Syam Nukavrapu Grace O’Connell Rachael Oldinski Joseph Palladino Anthony Passerini Amit Pathak Robert Peattie Yi-Xian Qin Michael Regnier David Rubenstein Edward Sander Jeff Saucerman Danial Shahmirzadi Agneta Simionescu Anita Singh Nathan Sniadecki Joel Stitzel Liping Tang W Robert Taylor Lian Tian Joe Tien Mark Van Dyke Jonathan Vande Geest Pamela VandeVord Leo Wan Rebecca Willits Huidan (Whitney) Yu Ji Zhang Wujie Zhang Chao Zhong

BIOMEDICAL ENGINEERING EDUCATION Jameel Ahmed Robert Allen Timothy Allen Jenny Amos Essy Behravesh Paul Benkeser Franklin Bost Eric Brey Dan Cavanagh Judy Cezeaux Naomi Chesler Jennifer Currey John Desjardins Colin Drummond Donna Ebenstein Chris Geiger Matthew Glucksberg Craig Goergen

Jay Goldberg Richard Goldberg William Guilford Shelly Gulati Brian Helmke Jennifer Kang-Mieler Mehmet Kaya Joe LeDoux Amy Lerner Rob Linsenmeier Angie Louie Jean-Michel Maarek Sundararajan Madihally Robert Malkin Mansoor Nasir Ruth Ochia Grace O’Connell Lars Olson Raquel Perez-Castillejos Marcia Pool James Rains Renata Ramos Alisha Sarang-Sieminski Ann Saterbak Agneta Simionescu Anita Singh Saion Sinha Jim Sweeney Alyssa Taylor Kurt Thoroughman Willis Tompkins Joe Tranquillo Conrad Zapanta Wujie Zhang

BIOMEDICAL IMAGING AND OPTICS Zhiliang Cheng Beata Chertok Bernard Choi David Cormode Bruce Damon Amber Doiron Timothy Duong Mario Fabiilli Michael Fenn Debadyuti (Rana) Ghosh Craig Goergen Javier Jo Efstathios Karathanasis Mehmet Kaya Vikram Kodibagkar Stephen LaConte Aaron Mohs Nozomi Nishimura Doug Noll Walter O’Dell B. Hyle Park Kaushik Parthasarathi Ramesh Raghupathy

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abstract reviewers Mahsa Ranji Brad Sutton Daniel Thorek Ken Tichauer Andrew Tsourkas Omid Veiseh Tilo Winkler Jing Yong Ye Baohong Yuan

CANCER TECHNOLOGIES Natalie Artzi Amy Brock Beata Chertok Rafael Davalos Emily Day Michael Fenn Rohan Fernandes Cyrus Ghajar Gargi Ghosh Esther Gomez Samir Iqbal Javier Jo Srivatsan Kidambi Pilnam Kim Michael King Joseph Kinsella Vikram Kodibagkar Konstantinos Konstantopoulos Piyush Koria Nastaran Kuhn James Lai Woo Lee Christopher Lemmon Wei Li Wenge Liu Jennifer Munson Mehdi Nikkhah Shelly Peyton Manu Platt Smitha Rao Cynthia Reinhart-King Carlos Rinaldi Keyue Shen Adrian Shieh Vassilios Sikavitsas Liping Tang Ken Tichauer Madeline Torres-Lugo Scott Verbridge Sihong Wang Yun Wu Edmond Young Baohong Yuan Wujie Zhang

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CARDIOVASCULAR ENGINEERING Taby Ahsan B. Rita Alevriadou Jorge Almodovar Natalie Artzi Aaron Baker Janet Barzilla Lauren Black III Nenad Bursac Gulden Camci-Unal Stuart Campbell Hung Cao Alesha Castillo Naomi Chesler Bernard Choi Youngjae Chun Thomas Claiborne Daniel Conway Guohao Dai Michael Davis Adam Engler Vittoria Flamini Steven George Craig Goergen Anjelica Gonzalez Yi Hong Marc Horner Tzung Hsiai Patrick Hsieh Jeffrey Jacot Javier Jo Mehmet Kaya Srivatsan Kidambi Hyunjoon Kong Sándor J. Kovács Jun Liao Shu Liu David Long Sundararajan Madihally Arash Mahboobin Gretchen Mahler Gil Marom Stuart Mitchell Jonathan Mynard Sriram Neelamegham Keith Neeves Mehdi Nikkhah Joseph Palladino Anthony Passerini Abhijit Patwardhan Robert Peattie Julie Phillippi Manu Platt Raj Prabhu Milica Radisic Michael Regnier David Rubenstein Michael Sacks Chander Sadasivan Alisha Sarang-Sieminski Narine Sarvazyan Jeff Saucerman

Saravan Kumar Shanmugavelayudam Jawaad Sheriff Agneta Simionescu Dan Simionescu Craig Simmons Saion Sinha Joao Soares Kevin Soucy Wei Tan Charles Taylor W Robert Taylor Lian Tian Mark Van Dyke Sara Vasconcrelos Sihong Wang Zhijie Wang Saami Yazdani Wei Yin Huidan (Whitney) Yu Ji Zhang

CELLULAR AND MOLECULAR BIOENGINEERING Michael Davis Tara Deans Junsang Doh Lindsay Fitzpatrick John Frampton Jason Gleghorn Heather Hayenga Brian Helmke Jeffrey Hubbell Gregory Hudalla Sha Jin Roland Kaunas Tamara Kinzer-Ursem Konstantinos Konstantopoulos Piyush Koria James Lai Nic Leipzig Allen Liu Shu Liu David Long Hongyan Ma Robert Mauck Teresa Murray Jiro Nagatomi Sriram Neelamegham Kaushik Parthasarathi Anthony Passerini Julie Phillippi Michelle Previtera Anand Ramasubramanian Michael Regnier Jeff Saucerman Keyue Shen Adrian Shieh Richard Sinden John Slater Junghae Suh Melody Swartz Leo Wan

Jun Wang Peter Yingxiao Wang Yun Wang

DEVICE TECHNOLOGIES AND BIOMEDICAL ROBOTICS Animesh Agarwal James Antaki Lemont Baker Tamara Baynham Lissett Bickford Hung Cao J-C Chiao Youngjae Chun Jennifer Currey Rafael Davalos Jaydip Desai Arielle Drummond Juan Hincapie Marc Horner Samir Iqbal Juan Jiménez Matt Kay Mehmet Kaya Massoud Khraiche Wen Ko Jeffrey La Belle James Lai Jinseok Lee Janie Mandrusov Keefe Manning Mike McShane Stuart Mitchell Mansoor Nasir Dominic Nathan Chris Pulliam James Rains Arthur Ritter Chander Sadasivan Sergey Shevkoplyas Kevin Soucy Sihong Wang Paul Yoo Bailin Zhang John Zhang Weiying Zhao

DRUG DELIVERY Jorge Almodovar Debra Auguste Lauren Black III Amy Brock Beata Chertok J-C Chiao Youngjae Chun Rhima Coleman Daniel Conway Guohao Dai Michael Davis Emily Day Tara Deans

Abstract Reviewers Erik Dreaden Craig Duvall Mario Fabiilli Akhilesh Gaharwar Gargi Ghosh Jason Gleghorn Anjelica Gonzalez Jordan Green Jianjun Guan Mariah Hahn Jered Haun Tamara Kinzer-Ursem Hyunjoon Kong Konstantinos Konstantopoulos Wenge Liu Manu Platt Narasimhan Rajaram Anand Ramasubramanian Kathryn Whitehead Saami Yazdani Kaiming Ye Wei Yin Edmond Young Yang Yun Lijie Grace Zhang

NANO AND MICRO TECHNOLOGIES Kyle Allen Shyam Aravamudhan Natalie Artzi Hung Cao Hao Cheng Beata Chertok J-C Chiao Youngjae Chun Rohan Fernandes Elain Fu Thomas Gaborski Akhilesh Gaharwar Jason Gleghorn SJ Claire Hur Samir Iqbal Salman Khetani Massoud Khraiche Srivatsan Kidambi Devrim Kilinc Jungkyu (Jay) Kim Pilnam Kim YongTae Kim Wei Li Elizabeth Loboa Xiaolong Luo Sundararajan Madihally Stuart Mitchell Aaron Mohs Mansoor Nasir Keith Neeves Narasimhan Rajaram Anand Ramasubramanian Smitha Rao Daniel Ratner Jai Rudra

Erkin Seker Saravan Kumar Shanmugavelayudam Keyue Shen Sergey Shevkoplyas Saion Sinha John Slater Nathan Sniadecki Leo Wan Jun Wang Sihong Wang Shannon Weigum Yun Wu Woon-Hong Yeo Edmond Young Lijie Grace Zhang Chao Zhong Pavel Zrazhevskiy

NEURAL ENGINEERING Shyam Aravamudhan Randolph Ashton Hung Cao Jeffrey Capadona J-C Chiao Jaydip Desai Jaimie Dougherty Lisa Flanagan John Frampton Ryan Gilbert Matthew Johnson Jennifer Kang-Mieler Mehmet Kaya Massoud Khraiche Srivatsan Kidambi Devrim Kilinc Srinivas Kota Teresa Murray Dominic Nathan Kevin Otto Chris Passaglia Matthew Schiefer Erkin Seker Anita Singh Sarah Stabenfeldt Katherine Steele Deanna Thompson Stuart Tobet Mark Van Dyke Pamela VandeVord Stephanie Willerth Rebecca Willits

NEW FRONTIERS AND SPECIAL TOPICS James Abbas Taby Ahsan Shyam Aravamudhan Beata Chertok Elain Fu Jason Gleghorn Ranu Jung James Lai Chenzhong Li Susan Lin Tan Liu Stuart Mitchell Ashwin Nair Nozomi Nishimura Anand Ramasubramanian Matthew Reilly Saravan Kumar Shanmugavelayudam Sergey Shevkoplyas Dan Simionescu Nathan Sniadecki Leo Wan Jun Wang Chao Zhong Pavel Zrazhevskiy

ORTHOPEDIC AND REHABILITATION ENGINEERING Animesh Agarwal Andrew Anderson Don Anderson Silvia Blemker Larry Bonassar Robert Bowles Stephanie Bryant Joel D Bumgardner John Cotton Eric Darling Tara Deans Kyle Allen Dawn Elliott F. Scott Gayzik Heath Henninger Christopher Hernandez Clark Hung Matthew Johnson Jeffrey La Belle Spencer Lake William Ledoux Amy Lerner Gregory Lewis Lucas Lu Wendy Murray Rachael Oldinski James Rains Robert Sah Katherine Saul Lori Setton Katherine Steele Joel Stitzel

Karen Troy Pamela VandeVord Diane Wagner Jeffrey Weiss Lise Worthen-Chaudhari Lijie Grace Zhang

RESPIRATORY BIOENGINEERING Said Audi Jason Bates Konstantin Birukov William Federspiel Marcel Filoche Donald Gaver F. Scott Gayzik Samir Ghadiali Jason Gleghorn Rebecca Heise Geoff Maksym Celeste Nelson Kaushik Parthasarathi Carrie Perlman Arthur Ritter Bela Suki Daniel Weiss Tilo Winkler

STEM CELL ENGINEERING Taby Ahsan Randolph Ashton Lauren Black III Stuart Campbell Rhima Coleman Guohao Dai Tara Deans Thomas Gaborski Akhilesh Gaharwar Tzung Hsiai Jeffrey Jacot Robert Mauck Jin Nam Syam Nukavrapu Julie Phillippi Eduardo Silva Deanna Thompson Gregory Underhill Leo Wan Stephanie Willerth Janet Zoldan

BMES 2014

67

abstract reviewers

TISSUE ENGINEERING Kyle Allen Deirdre Anderson Shyam Aravamudhan Natalie Artzi Randolph Ashton Samira Azarin Brendon Baker Lauren Black III Gary Bowlin Joel D Bumgardner Gulden Camci-Unal Stuart Campbell Rhima Coleman Guohao Dai Eric Darling Michael Davis Tara Deans Meng Deng Craig Duvall Mario Fabiilli Lindsay Fitzpatrick John Frampton Akhilesh Gaharwar Jason Gleghorn Anjelica Gonzalez Sheila Grant

Jianjun Guan Teja Guda Mariah Hahn Rebecca Heise Yi Hong Tzung Hsiai Patrick Hsieh Rita Issa Jeffrey Jacot Sha Jin Roland Kaunas Salman Khetani Srivatsan Kidambi Megan Killian Pilnam Kim YongTae Kim Matt Kipper Hyunjoon Kong Piyush Koria Joydip Kundu Nic Leipzig Jun Liao Elizabeth Loboa Maureen Lynch Hongyan Ma Sundararajan Madihally Gretchen Mahler Robert Mauck

Peter McFetridge Stuart Mitchell Jennifer Munson Jiro Nagatomi Ashwin Nair Jin Nam Hung Nguyen Mehdi Nikkhah Syam Nukavrapu Grace O’Connell Rachael Oldinski Rene Olivares-Navarrete Emmanuel Opara Robert Peattie Raquel Perez-Castillejos Julie Phillippi George Pins Michael Regnier David Rubenstein Wajeeh Saadi Alisha Sarang-Sieminski Scott Sell Blanka Sharma Vassilios Sikavitsas Eduardo Silva Agneta Simionescu Dan Simionescu Joao Soares

Patricia Soucy Sarah Stabenfeldt Wei Tan Liping Tang Deanna Thompson Joe Tien Stuart Tobet Gregory Underhill Mark Van Dyke Scott Verbridge Leo Wan Sihong Wang Yun Wang Zhijie Wang Stephanie Willerth Rebecca Willits Kaiming Ye Lijie Grace Zhang Wujie Zhang Chao Zhong Janet Zoldan

Congratulations to the

BMES 2014 class of Fellows Beth Winkelstein, PhD University of Pennsylvania

Robert Sah, MD, ScD University of California, San Diego

Cheng Zhu, PhD Georgia Institute of Technology

Song Li, PhD University of California, Berkeley

Deborah Leckband, PhD University of Illinois

Tejal Desai, PhD University of California, San Francisco

Donald Gaver, PhD Tulane University Guillermo Ameer, PhD Northwestern University Hanjoong Jo, PhD Georgia Institute of Technology

68

BMES 2014

BMES Fellow status is awarded to members who demonstrate exceptional achievements and experience in the field of biomedical engineering, and a consistent record of membership and participation in the Society.

BMES 2014

69

notes

70

BMES 2014

8:00AM-9:30AM Platform Sessions Thurs-1

2014 | OCTOBER 23 | Thursday

THURSDAY, October 23, 2014

TODAY’S HIGHLIGHTS PLATFORM SESSIONS Thurs-1 8:00am - 9:30am See pages 71-77, HBGCC

EXHIBIT HALL OPEN

9:30am - 5:00pm

HBGCC, Exhibit Hall A

POSTER SESSION

8:00 AM - 9:30 AM PLATFORM SESSIONS – Thurs - 1

Platform Sessions

Th-1

Track: Tissue Engineering, Cardiovascular Engineering OP-Thurs-1-1 - Room 001A

9:30am - 5:00pm See pages 93-124 , HBGCC, Exhibit Hall A Poster Viewing with Authors 9:30am - 10:30am

Blood Vessel Tissue Engineering

& Refreshment Break

8:00AM

PLENARY SESSION 10:30am - 12:15pm HBGCC, Lila Cockrell Theatre

State of the Society Fellows Presentation

Chairs: Kent Leach, Peter McFetridge

Human Tissue-Engineered Blood Vessels for In Vitro Drug Response Testing C. Fernandez1, R. Yen1, W. Reichert1, and G. Truskey1 1

Duke University, Durham, NC

8:15AM

Pericyte-Derived Matrix Alters Endothelial Cell Angiogenic Properties and Inflammatory Function

Gilda Barabino, PhD

P. Sava1, I. Cook1, B. Walker1, and A. Gonzalez1 1

Robert A. Pritzker Distinguished Lecture Life Redesigned: The Emergence of Synthetic Biology

Yale University, New Haven, CT

8:30AM

Dynamically-Perfused Multi-Scale Vascular Network Created within Thick Hydrogel using 3D Bio-Printing Technology V. Lee1, P. Vincent2, S-S. Yoo3, and G. Dai1 1 Rensselaer Polytechnic Institute, Troy, NY, 2Albany Medical College, Albany, NY, 3Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

James Collins, PhD

8:45AM

Celebration of Minorities in BME Luncheon

12:30pm - 1:45pm

Fabrication of Highly Vasoreactive and Robust Tissue Engineered Vascular Media Using Doxycycline Treatment: Implication for Vascular Tissue Engineering

Additional ticket purchase required

V. Bajpai1, P. Mistriotis1, Z. Chamanzar1, R. Carpenter1, and S. Andreadis1

HBGCC, Ballroom A

1

PLATFORM SESSIONS Thurs-2 2:00pm - 3:30pm See pages 78-84, HBGCC

SUNY Buffalo, Amherst, NY

9:00AM

Accelerating Cellular Spheroid Fusion Using Magnetic Forces to Fabricate a Vascular Tissue T. Olsen1, M. Casco1, D. Simionescu1, R. Visconti2, and F. Alexis1

Poster Viewing with Authors 3:30pm - 4:30pm & Refreshment Break

1

Clemson University, Clemson, SC, 2Medical University of South Carolina, Charleston, SC

9:15AM

HBGCC, Exhibit Hall A

Acellular Small Diameter Vascular Graft Evaluated In a Pre-clinical Animal Model

PLATFORM SESSIONS Thurs-3 4:30pm - 6:00pm

M. Koobatian1, R. Smith1, S. Row1, S. Andreadis1, and D. Swartz1

See pages 85-91, HBGCC

PLENARY SESSION

Computational Modeling and Simulation for Medical Devices

6:15pm - 7:30pm

HBGCC, Lila Cockrell Theatre

Hosted Receptions–Marriott Rivercenter and Marriott Riverwalk See page 62 for list

1

State University of New York at Buffalo, Amherst, NY

Track: Tissue Engineering, Stem Cell Engineering OP-Thurs-1-2 - Room 001B

Microfabrication and 3D Printing for Tissue Engineering Chairs: Adam Feinberg, Akhilesh Gaharwar 8:00AM

3D Printed Biological Machines Powered by Skeletal Muscle C. Cvetkovic1, R. Raman1, M. Rich1, R. Swetenburg2, B. Williams1, S. Stice2, H. Kong1, T. Saif1, and R. Bashir1 University of Illinois at Urbana-Champaign, Urbana, IL, 2The University of Georgia, Athens, GA

1

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Thursday | OCTOBER 23 | 2014

Platform Sessions

Th-1

Platform Sessions Thurs-1 8:00AM-9:30AM

8:15AM

9:15AM

K. Stevens1 and S. Bhatia1

E. Beck1, B. Lohman1, S. Kieweg1, S. Gehrke1, C. Berkland1, and M. Detamore1

Hierarchical Assembly for Guided Morphogenesis of Scaffold-free Tissues 1

Enabling Surgical Placement of Hydrogels Through Achieving Paste-Like Rheological Behavior Prior to Crosslinking

Massachusetts Institute of Technology, Cambridge, MA

1

University of Kansas, Lawrence, KS

8:30AM

Rapid Formation of Multicellular Spheroids with Controllable Microenvironment in Microfluidics-Generated Double Emulsion Droplets and Its Applications in Tissue Engineering

Bioinspired and Self Assembling Biomaterials I

H. Chan1 and K. Leong1 1

Track: Biomaterials OP-Thurs-1-4 - Room 006B

Duke University, Durham, NC

8:45AM

3D Printing Facilitated Scaffold-free Tissue Unit Fabrication

Chairs: George Pins, Jordan Green

Y. TAN1, D. Richards1, and Y. Mei1,2

8:00AM

1

Clemson University, Charleston, SC, 2Medical University of South Carolina, Charleston, SC

9:00AM

3D Printing of Complex Biological Scaffolds Using Freeform Reversible Embedding of Suspended Hydrogels (FRESH) T. Hinton1 and A. Feinberg1 1

Carnegie Mellon University, Pittsburgh, PA

A. Panitch1, C. Goergen1, G. Breur1, P. Snyder1, N. Vazquez-Portalatin1, and S. Sharma1 1

Purdue University, WEST LAFAYETTE, IN

8:30AM

Harnessing Cellular-Derived Forces to Control the Synthesis and Alignment of Novel ECM Materials

9:15AM

Robotic Microcontact Printing (R- CP) J. McNulty1, T. Klann1, G. Knight1, M. Salick1, L-S. Turng1, and R. Ashton1 1

Suppression of Osteoarthritis via Molecular Engineering of an Aggrecan Mimetic

University of Wisconsin Madison, Madison, WI

J. Schell1, B. Wilks1, X. Cao2, V. Shenoy2, and J. Morgan1 1

Brown University, Providence, RI, 2University of Pennsylvania, Philadelphia, PA

8:45AM

Track: Biomaterials, Tissue Engineering OP-Thurs-1-3 - Room 006A

Biomaterial Scaffolds I

University of Florida, Gainesville, FL, 2Illinois Institute of Technology, Chicago, IL, 3University of Chicago, Chicago, IL

1

RNA Localization to Phospholipid Membranes with Nucleolipids N. Kamat1 and J. Szostak1

8:00AM Invited

1

Biomaterials Track Overview 1

A. Restuccia1, Y. Tian2, J. Collier3, and G. Hudalla1

9:00AM

Chairs: Dan Simionescu, Jai Rudra

R. Carrier

Glycosylated Peptide Nanofibers to Modulate Galectin Bioactivity

Harvard University and Massachusetts General Hospital, Boston, MA

9:15AM

1

Injectable Oxidation-Responsive Fibrillar Assemblies are Processed by CD11c+ Populations in Skin

Northeastern University, Boston, MA

8:15AM

Osseointegration Capability of Direct Metal Laser Sintered Titanium Implants With Unique Surface Characterization: An In Vitro and In Vivo Evaluation S. Hyzy1, D. Cohen1, R. Clohessy1, A. Cheng2,3,4, B. Boyan1,2, and Z. Schwartz1,5 1 Virginia Commonwealth University, Richmond, VA, 2Georgia Institute of Technology, Atlanta, GA, 3Emory University, Atlanta, GA, 4Peking University, Beijing, China, People's Republic of, 5 University of Texas Health Science Center, San Antonio, TX

8:30AM

C. Brubaker1, D. Bonner1, E. Phelps1, and J. Hubbell1 1

Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland

Track: Drug Delivery, Nano to Micro Technologies OP-Thurs-1-5 - Room 006C

Nano/Micro Drug Delivery

Effect of Capillary Action on Bone Regeneration in Micro-Channel Ceramic Scaffolds

Chairs: Craig Duvall, Jered Haun

Y. Kim1, M-H. Hong2, C. Bae3, Y. Kim4, K. Kim4, and D. Oh5

Glucose-Responsive Insulin Delivery by Biomimetic Synthetic Vesicles

Trinity School, New York, NY, Columbia University, New York, NY, Chonnam National University, Gwangju, Korea, Republic of, 4Kyung Hee University, Yongin, Korea, Republic of, 5 Columbia Unoversity, New York, NY 1

2

3

8:00AM

Z. Gu1, W. Tai1, J. Di1, R. Mo1, and V. Subramanian1 1

University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC

8:45AM

8:15 AM

Elastomeric and Mechanically Stiff Nanocomposites for Bone Tissue Engineering

Nanostructured Polycaprolactone Thin Films For Enhanced Ocular Drug Delivery

P. Kerativitayanan1 and A. Gaharwar1

J. Kim1, C. Fox2, and T. Desai3 UCB-UCSF Graduate Program in Bioengineering, San Francisco, CA, 2Pharmaceutical Sciences and Pharmacogenomics Graduate Program in UCSF, San Francisco, CA, 3 Department of Bioengineering and Therapeutic Sciences in UCSF, San Francisco, CA 1

Texas A&M University, College Station, TX

1

9:00AM

Solid Freeform Fabrication of Biomaterials Scaffolds via Photopolymerization of High Internal Phase Emulsions N. Sears , J. Robinson , M. Whitely , and E. Cosgriff-Hernandez 1

1

1

1

Texas A&M University, College Station, TX

8:30AM 1

Nanostructured Mucoadhesive Microparticles for Their Enhanced Retention in Gastrointestinal Tract C. Park1, B. Huh1, M. Park1, S. Lee1, H. Hong1, and Y. Choy1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

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Seoul National University, Seoul, Korea, Republic of

8:00AM-9:30AM Platform Sessions Thurs-1

2014 | OCTOBER 23 | Thursday

8:45AM

A Dendrimer/Lipid Gene Delivery System for Ocular Gene Therapy D. Sun1, H. Maeno1, A. Malamas1, G. Yu1, T. Maeda1, A. Maeda1, K. Palczewski1, and Z-R. Lu1 1

Case Western Reserve University, Cleveland, OH

9:00AM

Track: Cancer Technologies OP-Thurs-1-7 - Room 007A

Platform Sessions

Th-1

Cancer Mechanobiology

Novel Electrospun Gelatin/insulin Formulation for Transbuccal Insulin Delivery

Chairs: Michael King, Christopher Lemmon

L. Xu1, N. Sheybani1, S. Ren1, G. Bowlin2, W. Yeudall1, and H. Yang1

Advancing Convergence and Innovation in Cancer Research: National Cancer Institute Center for Strategic Scientific Initiatives (CSSI)

1

Virginia Commonwealth University, Richmond, VA, 2University of Memphis, Memphis, TN

E. Greenspan1, M. Berny-Lang1, and J. Lee1

9:15AM

Transport Studies of Nanoscale Bacteria Enabled Autonomous Drug Delivery Systems (NanoBEADS) in an In-vitro Tumor Model M. Traore1 and B. Behkam1 1

8:00AM Invited

Virginia Tech, Blacksburg, VA

1

8:15 AM

Nuclear Limits to 3D Migration and Survival D. Discher1 1

Track: Biomechanics, Cellular and Molecular Bioengineering OP-Thurs-1-6 - Room 006D

Cell Biomechanics I

National Cancer Institute, NIH, Bethesda, MD

University of Pennsylvania, Philadelphia, PA

8:30AM

Matrix-Stiffness-Dependent Upregulation Of MT1-MMP Promotes An Invasive Epithelial Phenotype S. Carey1, K. Martin1, and C. Reinhart-King1 1

Cornell University, Ithaca, NY

Chairs: Elizabeth Loboa, Christopher Lemmon

8:45AM

8:00AM

K. Stroka1, M. Shriver2, B. Wong1, K. Konstantopoulos1, and A. Kontrogianni-Konstantopoulos2

Nanotopography Modulated Nuclear Deformation X. Yu1, A. Bruce1, R. Mezan1, L. Wang2, P. Fulay1, Y. Rojanasakul1, and Y. Yang1 West Virginia University, Morgantown, WV, 2The National Institute for Occupational Safety and Health, Morgantown, WV 1

8:15 AM

Platelet Mechanosensing on Collagen-Conjugated Substrates M. Kee1, Y. Qiu1, D. Myers1,2, R. Tran1, Y. Sakurai1,2, and W. Lam1,2 1

Georgia Institute of Technology, Atlanta, GA, 2Emory University, Atlanta, GA

8:30AM

Vascular Smooth Muscle Cell Behavior on Patterned PDMS Substrates R. Chen and D. Dean 1

1

1

Clemson University, Clemson, SC

8:45AM

Loss of Giant Obscurins Alters Breast Epithelial Cell Mechanobiology Johns Hopkins University, Baltimore, MD, 2University of Maryland, Baltimore, Baltimore, MD

1

9:00AM

Extracellular Matrix Stiffness Protects Carcinoma Cells from Sorafenib via JNK Signaling T. Nguyen1, M. Sleiman1, T. Moriarty1, W. Herrick1, and S. Peyton1 1

University of Massachusetts Amherst, Amherst, MA

9:15AM

Contractility as a Biophysical Signature of Metastasis for Primary Human Colon Cancer Cells M. Ali1, K. Tangella2, D. Ramkumar2, and T. Saif3 1 3

University of Illinois, Champaign, IL, 2Provena Covenant Medical Centre, Urbana, IL, University of Illinois at Urbana-Champaign, Urbana, IL

Impact of Membrane Cholesterol on Monocyte Biomechanics A. Saha1 and A. Ramasubramanian1 1

University of Texas at San Antonio, San Antonio, TX

9:00AM

Membrane Deformation and Bioeffects in Single Cells Produced by High Strain-Rate Loading Associated with Tandem Bubble Interaction F. Yuan1, C. Yang1, Y. Zhang1, G. Sankin1, and P. Zhong1 1

Duke University, Durham, NC

9:15AM

Dynamic Traction Forces of Spreading and Adherent Human Neutrophils S. Henry1, C. Chen2, J. Crocker1, and D. Hammer1 1

University of Pennsylvania, Philadelphia, PA, 2Boston University, Boston, MA

Track: Cardiovascular Engineering OP-Thurs-1-8 - Room 007B

Hemodynamics and Vascular Mechanics I Chairs: Daniel Bluestein, Keith Neeves 8:00AM

Platelet Thrombin Generation Under Flow W. Yin1, K. Bond1, V. Ngo1, and D. Rubenstein1 1

Stony Brook University, Stony Brook, NY

8:15 AM

Stress-induced Platelet Activation Potential in Abdominal Aortic Aneurysms K. Hansen1, A. Arzani1, and S. Shadden1 1

University of California, Berkeley, CA

8:30AM

Stiff Substrates Enhance Monocyte Recruitment from Flow J. MacKay1 and D. Hammer1 1

University of Pennsylvania, Philadelphia, PA

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73

Thursday | OCTOBER 23 | 2014

Platform Sessions Thurs-1 8:00AM-9:30AM

8:45AM Platform Sessions

Th-1

Simvastatin Ameliorates Substrate Stiffness Dependent Endothelial Dysfunction M. Lampi1, C. Faber1, J. Huynh1, J. Jones1, N. Nishimura1, and C. Reinhart-King1 1

Cornell University, Ithaca, NY

9:00AM

Refrigerated Platelets Respond to Physiologic Inhibitors, Evidence That Cold-Induced Activation Is Unlikely to Result in Disseminated Intravascular Coagulation K. Reddoch1, H. Pidcoke2, A. Cap2, and A. Ramasubramanian1 The University of Texas at San Antonio, San Antonio, TX, 2US Army Institute of Surgical Research, Fort Sam Houston, TX

1

9:15AM

Fibrin Generation and Transthrombus Pressure Gradients Regulate Thrombin Mediated Clot Growth R. Muthard1 and S. Diamond1 1

University of Pennsylvania, Philadelphia, PA

Track: Cellular and Molecular Bioengineering OP-Thurs-1-9 - Room 007C

Cell Adhesion Chairs: Sriram Neelamegham, Eric Boder 8:00AM

W. Thomas1, O. Yakovenko1, and K. Johnson1 University of Washington, Seattle, WA

Chairs: Brenton Hoffman, Nic Leipzig 8:00AM

α-Catenin Cytomechanics: Role in Cadherin-Dependent Adhesion and Mechanotransduction J. Wu1, A. Barry1, H. Tabdili1, I. Muhamed1, N. Shashikanth1, G. Gomez2, A. Yap2, C. Gottardi3, J. Rooij4, N. Wang1, and D. Leckband1 University of Illinois at Urbana-Champaign, Urbana, IL, 2University of Queensland, St. Lucia, Brisbane, Australia, 3Northwestern University, Chicago, IL, 4University Medical Center Utrecht, Utrecht, Netherlands

1

8:15 AM

Cyclic Anisotropic Strain Mediates TGFβ Activation in a TimeDependent Manner by Potentiating SMAD2 and RhoA L. Pagnozzi1 and J. Butcher1 1

Cornell University, Ithaca, NY

8:30AM

Cellular Tension Regulates TGFβ Signaling Through Discrete Spatial Organization Of TGFβ Receptors J. Rys1, C. DuFort2, M. Baird3, M. Davidson3, and T. Alliston2 UC Berkeley - UCSF, San Francisco, CA, 2UCSF, San Francisco, CA, 3Florida State University, Tallahassee, FL

8:45AM

Tissue Mechanics in Glioma Aggression Y. Miroshnikova1, J. Phillips1, K. Lobo1, H. Laklai1, T. McKnight1, and V. Weaver1

8:15AM

1

Kinetic Properties govern Mucin 16 (MUC16) and Podocalyxin (PODXL) adhesion to E- and L-selectins in Shear Flow D. Shea1, K. Stebe2, and K. Konstantopoulos1,3,4,5 Johns Hopkins University, Baltimore, MD, Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA, 3Johns Hopkins Institute for NanoBioTechnology, Baltimore, MD, 4Johns Hopkins Physical Sciences-Oncology Center, Baltimore, MD, 5Johns Hopkins Center of Cancer Nanotechnology Excellence, Baltimore, MD 1

Mechanotransduction I

1

When Affinity Is not Enough: Strong Ideal Bonds with the Gate Mechanism 1

Track: Cellular and Molecular Bioengineering, Biomechanics OP-Thurs-1-10 - Room 007D

2

8:30AM

ST3Gal-4 is the Primary (2,3) Sialyltransferase Regulating the Biosynthesis of E-, P- and L-selectin Ligands in Human Leukocytes

UCSF, San Francisco, CA

9:00AM

Determining Force Sensitive Protein-Protein Interactions in Focal Adhesions A. LaCroix1 and B. Hoffman1 1

Duke University, Durham, NC

9:15AM

Rationally-Designed FRET-based Molecular Tension Sensors A. LaCroix1 and B. Hoffman1 1

Duke University, Durham, NC

S. Neelamegham1, N. Mondal1, A. Buffone Jr.2, and J. Lau2 State University of New York at Buffalo, Buffalo, NY, 2Roswell Park Cancer Institute, Buffalo, NY

1

8:45AM

Allosteric Regulation of Cadherin-mediated Intercellular Adhesion by Inside-out Signaling D. Leckband1, N. Shashikanth1, J. Newhall1, Y. Petrova2, M. Spano2, and B. Gumbiner2

Track: Nano to Micro Technologies, Translational Biomedical Engineering OP-Thurs-1-11 - Room 008A

BioMEMS I

1

Chairs: James Tunnell, Catherine Klapperich

9:00AM

8:00AM Invited

C. Ge1 and C. Zhu1

C. Klapperich1

University of Illinois, Urbana, IL, 2University of Virginia College of Medicine, Charlottesville, VA

Catch Bond In TCR-CD3 Interaction 1

Georgia Institute of Technology, Atlanta, GA

Nano to Micro Technologies Track Overview 1

Boston University, Boston, MA

9:15AM

8:15 AM Invited

W. Okech1, D. Hocking1, and I. Sarelius1

H. Lu1

An ECM Fibronectin Matricryptic Site Contributes To Mechanosignaling In Endothelial Cells Under Flow 1

University of Rochester, Rochester, NY

High-throughput High-content Developmental Biology and Neurogenetics 1

Georgia Institute of Technology, Atlanta, GA

8:45AM

A Microdevice for Simultaneous Applications of Topographic Cues and Cyclic Tensile Strains to Live Cells P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

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BMES 2014

Q. Wang1, K. Wei1, and Y. Zhao1 1

Ohio State University, Columbus, OH

8:00AM-9:30AM Platform Sessions Thurs-1

2014 | OCTOBER 23 | Thursday

9:00AM

An Ultrathin Flexible Carbon Nanotube Microelectrode Array for Neural Recording and Stimulation W. Yi1, Z. Feng1, C. Zhou1, J. Cavanaugh1, C. Chen1, and M-C. Cheng1 1

Wayne State University, Detroit, MI

9:15AM

Nanomagnetic Actuation: Remote Control of Cell Signaling J. Dobson1, A. Monsalve1, B. Hu2, and A. El Haj2 University of Florida, Gainesville, FL, 2Keele University, Stoke on Trent, United Kingdom

1

Track: Device Technologies and Biomedical Robotics, New Frontiers and Special Topics OP-Thurs-1-13 - Room 201

Platform Sessions

Th-1

Implantable Devices and Implantable Electronics Chairs: Rafael Davalos, Lemont Baker 8:00AM Invited

Track: Nano to Micro Technologies, Cellular and Molecular Bioengineering OP-Thurs-1-12 - Room 008B

Microfluidic Platforms I

Overview of Development and Commercialization of Implantable Vagus Nerve Stimulation Systems M. Morris1 1

Cyberonics, Inc., Houston, TX

8:30AM

Chairs: Xiaolong Luo, Edmond Young

Liquid Crystal Polymer (LCP)-based Device Packaging for Auditory and Visual Prostheses

8:00AM

S. Kim1, J. Kim1, and J. Jeong1

M. Vazquez

8:45AM

1

Microfluidic Platforms Overview The City College of New York (CUNY), New York, NY

8:15 AM

A Chemotaxis-Based Microfluidic Sorting Platform S. Suh , M. Traore , and B. Behkam 1

1

1

Virginia Tech, Blacksburg, VA

1

Spontaneous Neutrophil Migration Patterns in Burn Patients during Sepsis C. Jones1,2,3, M. Moore1, L. Dimisko1,2, A. Alexander1, A. Ibrahim1, B. Hassell2, R. Tompkins1, S. Fagan1, and D. Irimia1,2,3 Massachusetts General Hospital and Harvard Medical School, Boston, MA, 2BioMEMS Resource Center, Center for Engineering in Medicine and Surgical Services, Boston, MA, 3 Shriners Hospital for Children, Boston, MA 1

Shear-free Microfluidic Platform for the Chemotaxis and Rapid Labeling of Cells H. Chung1, C. Chan1,2, T. Khire1, G. Marsh1, A. Clark1, R. Waugh1, and J. McGrath1 University of Rochester, Rochester, NY, 2Simpore Inc., West Henrietta, NY

9:00AM

Nanowire Electrophysiology For Cell Sorting And Screening A. Bell , D. Vercosa , and J. Robinson , 1

1

1 2

Rice University, Houston, TX, 2Baylor College of Medicine, Houston, TX

9:15AM

A Standing Surface Acoustic Wave (SSAW)-based Cell Co-culture Platform S. Li1, F. Guo1, Y. Chen1, X. Ding1, P. Li1, C. Cameron1, and T. Huang1 1

H. Vihvelin1, J. Leadbetter1, J. Brown1, and R. Adamson1 1

Dalhousie University, Halifax, NS, Canada

Reconfigurable Analog-to-Digital Converter for Implantable Bioimpedance Monitoring T. Randall1, I. Mahbub1, F. Quaiyum1, and S. Islam1 1

University of Tennessee, Knoxville, Knoxville, TN

9:15AM

Surface Plasmon Resonance Imaging of Materials that Reduce Staphylococcus aureus Contamination P. Abadian1 and E. Goluch1

8:45AM

1

Compensating For Tissue Changes In Ultrasonic Transcutaneous Energy Transfer Systems

9:00AM

8:30AM

1

Seoul National University, Seoul, Korea, Republic of

The Pennsylvania State University, University Park, PA

1

Northeastern University, Boston, MA

Track: Biomechanics, Neural Engineering OP-Thurs-1-14 - Room 103B

Head Injury Chairs: Stefan Duma, Beth Winkelstein 8:00AM Invited

Biomechanics Track Overview S. Marguiles1 1

University of Pennsylvania, Philadelphia, PA

8:15 AM

Blast Induced Neurotrauma Leads To Changes In The Epigenome Z. Bailey1, S. Sajja1, W. Hubbard1, E. Ereifej1, and P. VandeVord1 1

Virginia Polytechnic Institute and State University, Blacksburg, VA

8:30AM

Brain Deformation, Structural Damage, and Biochemical Alterations in Mild Blast-Induced TBI in Rats N. Race1,2, M. Walls1, S. Vega-Alvarez1, S. Song1, A. Kim1, T. Zhang1, G. Kuziel1, Y. Gu1, B. Ziaie1, and R. Shi1 Purdue University, West Lafayette, IN, 2Indiana University School of Medicine, Indianapolis, IN

1

8:45AM

Blast Injury Augments Pro-inflammatory Phenotype in Rat Hippocampus M. Waters1, S. Sajja2, P. VandeVord1, and M. Van Dyke1 Virginia Polytechnic Institute and State University, Blacksburg, VA, 2Johns Hopkins School of Medicine, Baltimore, MD

1

BMES 2014

75

Thursday | OCTOBER 23 | 2014

Platform Sessions

Th-1

Platform Sessions Thurs-1 8:00AM-9:30AM

9:00AM

8:15 AM

N. Bahrami1, E. Davenport1, C. Whitlow1, J. Urban1, Y. Jung1, M. Espeland1, D. Rosenbaum1, C. Vaughan2, G. Gioia2, A. Powers1, J. Stitzel1, and J. Maldjian1

W. Murray1, K. Saul2, M. Johanson3, G. Gold4, and V. Hentz4

TBSS Analysis of White Matter Changes related to Head Impacts in High School Football

Brachioradialis Muscle Volume and Pinch Force Following Tendon Transfer Northwestern University, Chicago, IL, 2North Carolina State University, Raleigh, NC, 3VA Palo Alto Health Care System, Palo Alto, CA, 4Stanford University, Palo Alto, CA

1

Wake Forest University School of Medicine, Winston Salem, NC, 2Children’s National Medical Center, Washington, DC

1

8:30AM

9:15AM

High Intensity Sound Wave Transduction from the Ear Canal to Middle Ear R. Gan1, D. Nakmali1, and Z. Yokell1 1

Muscle Progenitor Cell Regenerative Capacity in the Torn Rotator Cuff G. Meyer1, A. Farris2, E. Sato3, J. Lane3, S. Ward3, and A. Engler3 Washington University in St. Louis, St. Louis, MO, 2The University of Kansas, Lawrence, KS, 3UCSD, La Jolla, CA

1

University of Oklahoma, Norman, OK

8:45AM

Track: Bioinformatics, Computational and Systems Biology OP-Thurs-1-15 - Room 202A

The Role of Dystrophins on Force Transmission in Skeletal Muscle

Single Cell, Heterogeneity, Noise

Spatial Distribution and Clustering of Fatty Infiltration Following Rotator Cuff Tear in the Elderly

C. Zhang1 and Y. Gao1 1

9:00AM

Chairs: Kyung Kim, Jun Wang

K. Saul1, A. Santago2, and M. Vidt2 North Carolina State University, Raleigh, NC, 2Wake Forest School of Medicine, WinstonSalem, NC

1

8:00AM Invited

Paracrine Signaling Reduces Cell-to-Cell Heterogeneity and Amplifies Macrophage Response to TLR4 Stimulation

9:15AM

Eccentric Contractions in Gait Lead to Selective Muscle Degeneration in Duchenne Muscular Dystrophy

Q. Xue1, Y. Lu1, M. Eisele1,2, N. Khan1, R. Fan1, and K. Miller-Jensen1 1

Yale University, New Haven, CT, 2University of Stuttgart, Stuttgart, Germany

X. Hu1, S. Peirce1, and S. Blemker1

8:30AM

Systematic Analysis of Drug-Induced Adaptive Response in Melanoma M. Fallahi-Sichani , N. Moerke , M. Niepel , T. Zhang , N. Gray , and P. Sorger 1

1

1

1

1

1

Harvard Medical School, Boston, MA

8:45AM

Nonlinear Biochemical Signal Processing via Noise Propagation K. Kim1, H. Qian1, and H. Sauro1 1

Cornell University, Ithaca, NY

University of Washington, Seattle, WA

9:00AM

Fluorescent In-Situ Sequencing of Single-Cells by Sequential Fish A. Coskun and L. Cai 1

1

1

University of Virginia, Charlottesville, VA

1

Track: Biomedical Imaging and Optics, Translational Biomedical Engineering OP-Thurs-1-17 - Room 203A

Applied Biomedical Imaging Techniques Chairs: Debadyuti (Rana) Ghosh,Vikram Kodibagkar 8:00AM

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA

Photoacoustic Monitoring to Stratify Photodynamic Therapy Response in Glioblastoma

9:15AM

S. Mallidi1, K. Watanabe2, D. Timerman1, and T. Hasan1

Single-Cell Analysis for Predicting Tumor Structure

1

J. Wang1

8:15 AM

1

1

SUNY Albany, Albany, NY]

Harvard Medical School, Boston, MA, 2Canon USA Inc, Boston, MA

Chemical Imaging in Assessment of Diseases: Fourier Transform Infrared Imaging Accurately Determines Cardiac Transplant Rejection S. Tiwari1,2, V. Reddy3, J. Raman3, and R. Bhargava1,2

Track: Orthopaedic and Rehabilitation Engineering, Biomechanics OP-Thurs-1-16 - Room 202B

Skeletal Muscle Mechanics Chairs: Silvia Blemker 8:00AM Invited

Opportunities in Biomedical Engineering for Solving Clinical Problems Associated with Skeletal Muscle Health S. Blemker1 1

University of Virginia, Charlottesville, VA

University of Illinois at Urbana Champaign, Urbana, IL, 2Beckman Institute for Advanced Science and Technology, Urbana, IL, 3Rush University Medical Center, Chicago, IL

1

8:30AM

Laser Speckle Imaging To Detect Pulsatile Flow In The Teeth C. Regan1, B. Yang1, K. Mayzel1, P. Wilder-Smith1, and B. Choi1 1

University of California, Irvine, Irvine, CA

8:45AM

In vivo Ultrasound and Functional Photoacoustic Imaging of the Development of Birth Defects C. Bayer1, B. Wlodarczyk1, G. Luke1, R. Finnell1, and S. Emelianov1 1

The University of Texas at Austin, Austin, TX

9:00AM

Dual-Modality Approach with Rod-Shaped Viral Nanoparticles for Targeting and Treatment of Thrombosis A. Wen1, Y. Wang2, K. Jiang1, A. Yang1, H. Gao2, X. Yu1, D. Simon2, and N. Steinmetz1 Case Western Reserve University, Cleveland, OH, 2Case Cardiovascular Center, Cleveland, OH

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

76

BMES 2014

8:00AM-9:30AM Platform Sessions Thurs-1

2014 | OCTOBER 23 | Thursday

9:15AM

Targeted Gold Nanoparticles For Contrast-Enhanced Detection of Breast Microcalcifications L. Cole , T. Vargo-Gogola , and R. Roeder 1

1

2

1

University of Notre Dame, Notre Dame, IN, 2Indiana University School of Medicine - South

Bend, South Bend, IN

Track: Biomedical Engineering Education (BME) OP-Thurs-1-18 - Room 203B

Innovations in BME Education Chairs: Naomi Chesler, Conrad Zapanta 8:00AM

Integrating Improvisational Acting and Inventive Problem Solving in Biomedical Engineering J. Antaki1 and J. Zell2 1

Carnegie Mellon University, Pittsburgh, PA, 2Steel City Improv, Pittsburgh, PA

Track: Translational Biomedical Engineering, Device Technologies and Biomedical Robotics OP-Thurs-1-19 - Ballroom A

Platform Sessions

Th-1

Biomedical Products and Devices Chairs: Mehdi Nikkhah, Robert Mauck 8:00AM Invited

Invention and Innovations with Aspirin: From Willow Bark to PolyAspirin K. Uhrich1 1

Rutgers, The State University of New Jersey, Piscataway, NJ

8:30AM

Field Validation of a Mobile Phone Microscope as a Screening Tool for Oral Cancer in India A. Skandarajah1, C. Reber1, P. Gurpur2, A. Jennifer3, G. Paladini4, M. Kollegal2, L. Ladic5, and D. Fletcher1 University of California, Berkeley, Berkeley, CA, 2Siemens, Bangalore, India, 3Christian Medical College, Vellore, India, 4Siemens, Princeton, NJ, 5Siemens, Tarrytown, NY

1

8:15 AM

Incorporating Anatomical Modeling with 3D Printing into the Biomedical Curriculum J. MacDonald1 and S. Sharma1 1

DeVry Univeristy, Chicago, IL

8:30AM

Ethics in Engineering Education K. Reyer1, M. Cantwell1, P. Lam1, R. Rafferty1, and K. Billiar1 1

Worcester Polytechnic Institute, Worcester, MA

8:45AM

Immediate Feedback on Computer Code Improves Problem Success E. Greenwald1 and J. Saucerman1 1

University of Virginia, Charlottesville, VA

9:00AM

Unique Hospital and Patient-based Design Course Encompassing STEM Interactive Learning Activities

8:45AM

A Novel ROS Responsive Polymer Based Lab-on-a-Chip Sensor for Detection of Circulating Lipid Hydroperoxides K. Aran1, J. Paredes1, A. Acharya1, J. Yau1, D. Liepmann1, and N. Murthy1 1

University of California Berkeley, berkeley, CA

9:00AM

On-demand Biofilm-removal Urinary Catheter V. Levering1, Q. Wang1, P. Shivapooja1, X. Zhao1, and G. López1 1

Duke University, Durham, NC

9:15AM

Cold Platelets Demonstrate Superior Clotting Properties Compared To Standard-Of-Care At Room Temperature P. Nair1, K. Reddoch1, C. Nguyen1, H. Pidcoke2, A. Cap2, and A. Ramasubramanian1 1

University of Texas at San Antonio, San Antonio, TX, 2U.S Army, San Antonio, TX

E. Hardy1,2,3, W. Newstetter2, and W. Lam1,2,3 Emory University, Atlanta, GA, 2Georgia Institute of Technology, Atlanta, GA, 3Children's Healthcare of Atlanta, Atlanta, GA

1

9:15AM

"Boot Camp" Training In Cellular Bioengineering To Accelerate Research Immersion For REU Participants D. Shreiber1, P. Moghe1, and C. Roth1 1

Rutgers, The State University of New Jersey, Piscataway, NJ

Professional Integrity Workshop: Best Practices for Publishing Your Work (Authorship) (Pre-Registration Required)

8:00am - 9:30am Henry B. Gonzalez Convention Center, Room 102AB BMES, Alpha Eta Mu Beta (AEMB) National BME Honor Society and the American Physiological Society (APS) are hosting a professional development workshop designed for early career students who plan to publish their research and want to learn best practices in publication ethics. The topic of this year’s session is Authorship. Join us to discuss best practices for deciding authorship, revising authorship order, resolving authorship disputes, and utilizing available resources to publish your work with confidence. This session material is based upon work supported by the National Science Foundation to APS/BMES/SBE under Grant No. SES-1238368.

BMES 2014

77

Thursday | OCTOBER 23 | 2014

Platform Sessions Thurs-2 2:00pM-3:30PM

THURSDAY, October 23, 2014 2:00 PM - 3:30 PM PLATFORM SESSIONS – Thurs - 2

Platform Sessions

Th-2

Track: Tissue Engineering OP-Thurs-2-1 - Room 001A

Track: Tissue Engineering, Biomaterials OP-Thurs-2-2 - Room 001B

Scaffolds and Surfaces for Tissue Engineering I Chairs: Meng Deng, Craig Duvall

Tissue Engineering of Models for Study of Disease and Drug Discovery

2:00PM

Chairs: Elizabeth Loboa, Roland Kaunas

Y. Du1, W. Liu1, and Y. Li 1

2:00PM

Modeling Genetic Hypertrophic Cardiomyopathy In Vitro with Isogenic, Engineered Cardiac Micro-Tissues N. Huebsch1, M. Mandegar1, P. Loskill2, Z. Ma2, L. Judge1, J. Yoo1, A. Sheehan1, A. Truong1, N. Devishar2, J. Wang2, P. Lizarraga1, P-L. So1, K. Healy2, and B. Conklin1 Gladstone Institute of Cardiovascular Disease, San Francisco, CA, 2University of California, Berkeley, Berkeley, CA

Microcryogels As Injectable 3-D Cellular Microniches For Site-directed And Augmented Cell Therapy 1

2:15PM

Hydrogel-based, Microstructural Building Blocks for Fabricating Scaffolds that Support Organized Tissues Formation in 3D L-H. Han1, X. Tong1, and F. Yang1,2 1

1

2:15PM

Molecular and Functional Roles of Cardiac Fibroblasts in Pressureoverload Induced Heart Failure Y. Li1, H. Asfour1, L. Mao1, H. Rockman1, and N. Bursac1 1

Duke University, Durham, NC

Tsinghua University, Beijing, China, People's Republic of

Stanford University School of Medicine, Stanford, CA, 2Stanford University, Stanford, CA

2:30PM

Generating an Off-the-Shelf In Vivo Cell Capture System on a Decellularized Biomaterial using Modified Antibodies for Venous Valve Replacement D. Anderson1, J. Glynn1, D. Pavcnik1, and M. Hinds1 1

Oregon Health & Science University, Portland, OR

2:30PM

2:45PM

E. Lippmann1, A. Al Ahmad1, S. Azarin1, S. Palecek1, and E. Shusta1

S. Grant1, J. Zhu2, and D. Grant1

A Retinoic Acid-Enhanced Human Blood-Brain Barrier Coculture Model from Scalable Cell Sources 1

University of Wisconsin, Madison, WI

Gold Nanoparticle-Collagen Templates Enhance Stability and Cell Infiltration in an In Vivo Study 1

University of Missouri, Columbia, MO, 2EternoGen, LLC, Columbia, MO

2:45PM

3:00PM

E. Moran1,2, B. Gaston1, P. Baptista1, J. Sparks3, D. Ruderman4, S. Mumenthaler4, P. Macklin4, and S. Soker1,2

A. Aijaz1, R. Faulknor1, F. Berthiaume1, and R. Olabisi1

Bioengineered Livers as a Model to Study Cancer Metastasis Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, 2Virginia TechWake Forest School of Biomedical Engineering and Sciences, Winston-Salem, NC, 3Miami University, Oxford, NC, 4University of Southern California, Los Angeles, CA

1

3:00PM

An Osteochondral Microphysiological System To Study The Pathogenesis Of Osteoarthritis And The Effect Of Hormonal Exposure

PEGDA Microencapsulated Insulin-Secreting Cells Accelerate Wound Closure 1

Rutgers, The State University of New Jersey, New Brunswick, NJ

3:15PM

Capture of VEGFR-expressing Stem Cells under Flow R. Smith Jr.1, M. Koobatian1, D. Swartz1, and S. Andreadis1,2 State University of New York, University at Buffalo, Buffalo, NY, 2Center of Excellence in Bioinformatics and Life Sciences, Buffalo, NY

1

R. Gottardi1,2, L. Hang1, T. Lozito1, P. Alexander1, K. Clark1, E. Sefton3, T. Woodruff3, and R. Tuan1 University of Pittsburgh, Pittsburgh, PA, 2Ri.MED Foundation, Palermo, Italy, 3Northwestern University, Chicago, IL

1

3:15PM

Long Term In Vitro Culture of Mature White Adipose Tissue R. Abbott1, R. Wang1, K. Burke1, and D. Kaplan1 1

Tufts University, Medford, MA

Track: Biomaterials OP-Thurs-2-3 - Room 006A

Therapeutic and Theranostic Biomaterials I Chairs: Elizabeth Loboa, Smitha Rao 2:00PM

A Novel Thermoresponsive Polydiolcitrate for Transcatheter Arterial Embolization Therapy J. Yang1, S-K. Lee2, M. Niekrasz2, A. Chang2, B. Shah2, and G. Ameer1,3 Northwestern University, Evanston, IL, 2University of Chicago, Chicago, IL, 3Feinberg School of Medicine, Chicago, IL

1

2:30PM

Silver Nanoparticle-Embedded Polymersome Nanocarriers for the Treatment of Antibiotic-Resistant Infections B. Geilich1 and T. Webster1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

78

BMES 2014

Northeastern University, Boston, MA

2:00pM-3:30pm Platform Sessions Thurs-2

2014 | OCTOBER 23 | Thursday

2:45PM

Polyanhydride Nanoparticle Delivery Platform Enables Enhanced Killing of Filarial Worms A. Binnebose1, R. Martin1, S. Haughney1, B. Narasimhan1, and B. Bellaire1 1

Iowa State University, Ames, IA

Drug Delivery in Tissue Engineering I

3:00PM

Dialysis-like Treatment of Sepsis Through Cleansing Pathogens from the Blood Stream using Functionalized Polysulfone Hollow Fibers T. Didar1, A. Watters1, D. Leslie1, J. Kang1, M. Cartwright1, A. Graveline1, A. Waterhouse1, M. Super1, and D. Ingber1 1

Wyss Institute at Harvard University, Boston, MA

J. Min , , R. Braatz , and P. Hammond , 1

Platform Sessions

2:00PM

Ultra-Thin Polymer Coatings for Sustained Localized RNA Interference to Improve Diabetic Wound Healing 1

Tunable Staged Release Of Therapeutics From Layer-By-Layer Coating With Clay Interlayer Barrier 1

Chairs: Anjelica Gonzalez, Rhima Coleman

S. Castleberry1, B. Almquist1, and P. Hammond1

3:15PM

1 2

Track: Drug Delivery, Tissue Engineering OP-Thurs-2-5 - Room 006C

1 2

MIT, Cambridge, MA, Koch Institute of Integrative Cancer Research, Cambridge, MA 2

2:15PM

Controlled Release Through Physical Collagen Modification mediated by Collagen Mimetic Peptides M. Urello1, M. Sullivan1, and K. Kiick1 1

Track: Biomaterials, Cellular and Molecular Bioengineering OP-Thurs-2-4 - Room 006B

Biomaterials for Controlling Cell Environment I

Massachusetts Institute of Technology, Cambridge, MA

University of Delaware, Newark, DE

2:30PM

Controlled Release of TGFβ Receptor II Inhibitor to Control Cardiac Fibrosis Z. Fan1, M. Fu1, Z. Li1, X. Li1, Y. Xu1, and J. Guan1 1

The Ohio State University, Columbus, OH

2:45PM

Chairs: Mariah Hahn, Blanka Sharma

Growth Factors Engineered for Super-affinity to the Extracellular Matrix Enhance Tissue Healing

2:00PM

M. Martino1, P. Briquez2, E. Guc2, F. Tortelli2, W. Kilarski2, S. Metzger2, J. Rice3, G. Kuhn4, R. Muller4, M. Swartz2, and J. Hubbell2

A. Lisella1, A. El Haj1, and J. Dobson2

1 Osaka University, Osaka, Japan, 2EPFL, Lausanne, Switzerland, 3Tennessee Tech University, Cookeville, TN, 4ETHZ, Zurich, Switzerland

Magneto-Active Dynamic Screening for Drug Discovery 1

Keele University, Stoke on Trent, United Kingdom, 2University of Florida, Gainesville, FL

2:15PM

A Mechanistic Investigation Of How A Decorin Mimic Controls Intimal Hyperplasia R. Scott1 and A. Panitch1

Sustained Release and Bioactivity of Antibiotics from Keratin Hydrogels In Vitro and in a Porcine Wound Model D. Roy1,2, R. Hall3, L. Burnett2, S. Tomblyn2, R. Christy1, and J. Saul3 U.S. Army Institute for Surgical Research, Fort Sam Houston, TX, 2KeraNetics, LLC, Winston-Salem, NC, 3Miami University, Oxford, OH

1

Purdue University, West Lafayette, IN

1

2:30PM

Spatiotemporal Control of Stem Cell Fate via Photoreversible Protein Patterning of Hydrogels C. DeForest1,2 and D. Tirrell2 1

3:00PM

3:15PM

Local Delivery of Aspirin-Triggered Resolvin D1 for Inflammation Modulation in Regenerative Medicine C. Powell1 and E. Botchwey1

University of Washington, Seattle, WA, 2California Institute of Technology, Pasadena, CA

1

Georgia Institute of Technology, Atlanta, GA

2:45PM

3D Spatially Organized PEG-based Hydrogels as an Aortic Valve Coculture Model to Study Valve Disease D. Puperi , L. Balaoing , J. West , and J. Grande-Allen 1

1

2

1

Rice University, Houston, TX, 2Duke University, Durham, NC

1

3:00PM

Spatiotemporal Delivery of Growth Factors to Hepatocytes via Polyelectrolyte Multilayers C. Lin1, K. Ballinger1, M. Kipper1, and S. Khetani1 1

Colorado State University, Fort Collins, CO

3:15PM

Track: Biomechanics, Cellular and Molecular Bioengineering OP-Thurs-2-6 - Room 006D

Cell Biomechanics II Chairs: Deborah Leckband, Jiro Nagatomi 2:00PM

Cyclic Stress-Relaxation Paradigm Causes Cell Stiffening H. Babahosseini1, J. Strobl1, and M. Agah1 Virginia Tech, Blacksburg, VA

Modulating Sub-cellular Processing of Single Wall Carbon Nanotubes by Controlling Dispersing Agent

1

B. Holt1, K. Dahl1, and M. Islam1

Mechanosensing of Shear Stress Requires VE-cadherin Tyrosine 658

1

Carnegie Mellon University, Pittsburgh, PA

2:15PM

D. Conway1 and M. Schwartz2 1

Virginia Commonwealth University, Richmond, VA, 2Yale University, New Haven, VA

2:30PM

Progesterone Alters the Mechanobiology of Primary Human Cervical Fibroblasts V. Shukla1, M. Schickel1, D. Kniss1, and S. Ghadiali1 1

The Ohio State University, Columbus, OH

BMES 2014

79

Th-2

Thursday | OCTOBER 23 | 2014

Platform Sessions Thurs-2 2:00pM-3:30PM

2:45PM

Activation of IGF1-RUNX2 Pathway Reveals Changes in Cellular Phenotype in Non-Syndromic Forms of Craniosynostosis. Z. Al-Rekabi1,2, A. Leonard1, S. Park2, J. Gustafson2, C. Clarke2, M. Cunningham1,2, and N. Sniadecki1 1

Platform Sessions

Th-2

University of Washington, Seattle, WA, 2Seattle Children’s Research Institute, Seattle, WA

Track: Cardiovascular Engineering OP-Thurs-2-8 - Room 007B

Hemodynamics and Vascular Mechanics II Chairs: Shu Liu, B. Rita Alevriadou

3:00PM

Heterogeneity of Infarct Collagen Orientation Emerges In Silico Based on Long-range Cell Interaction

2:00PM

W. Richardson1, A. Rouillard2, and J. Holmes1

Flow Alters Genome-wide DNA Methylation, Regulating Endothelial Ggene Expression and Atherosclerosis

University of Virginia, Charlottesville, VA, 2Icahn School of Medicine at Mount Sinai, New York, NY

J. Dunn1, H. Qiu1, S. Kim1, D. Jjingo2, R. Hoffman1, C. Kim1, I. Jang1, D. Son1, D. Kim1, C. Pan2, Y. Fan2, K. Jordan2, and H. Jo1

1

Georgia Institute of Technology & Emory University, Atlanta, GA, 2Georgia Institute of Technology, Atlanta, GA

1

3:15PM

Mechanical Origins of Axial Rotation in Chick Embryos

2:15PM

Z. Chen1, Q. Guo2, E. Dai1, N. Forsch1, and L. Taber1 Washington University in St. Louis, St. Louis, MO, 2Fuzhou University, Fuzhou, China, People's Republic of

1

Atypical Mechanosensitive MicroRNA-712 Derived From Preribosomal RNA Induces Endothelial Inflammation and Atherosclerosis S. Kumar1, D. Son1, W. Takabe1, C-W. Ni1, C. Kim1, I. Jang1, N. Alberts-Grill1, and H. Jo2

Track: Cancer Technologies OP-Thurs-2-7 - Room 007A

1

Emory University, Atlanta, GA, 2Georgia Tech and Emory University, Atlanta, GA

2:30PM

Tumor Microenvironment I

Association Between RV-PA Functional Phenotype and NT-proBNP in Pediatric Pulmonary Hypertension

Chairs: Konstantinos Konstantopoulos,Vassilios Sikavitsas

V. Kheyfets1,2, J. Dunning1,2, U. Truong2, D. Ivy2, K. Hunter1,2, and R. Shandas1,2 1

2:00PM Invited

The NCI's Provocative Questions Initiative: Program Overview and Evaluation Efforts M. Berny-Lang1, J. Lee1, and E. Greenspan1 1

University of Colorado Denver, Aurora, CO, 2Children's Hospital Colorado, Aurora, CO

2:45PM

Effects of Age on the Mechanical Properties and Structural Characteristics of the Human Femoropopliteal Arteries A. Kamenskiy1, I. Pipinos1, N. Phillips1, Y. Dzenis2, and J. MacTaggart1

National Cancer Institute, NIH, Bethesda, MD

University of Nebraska Medical Center, Omaha, NE, 2University of Nebraska-Lincoln, Lincoln, NE

1

2:15PM

Suicide Gene-Engineered Stromal Cells Reveal a Dynamic Regulation of Cancer Metastasis K. Shen1, S. Luk1, J. Elman1, R. Murray1, M. Yarmush1,2, and B. Parekkadan1,3 Harvard Medical School and Massachusetts General Hospital, Boston, MA, Rutgers University, Piscataway, NJ, 3Harvard Stem Cell Institute, Cambridge, MA

1

2

2:30PM

Macrophage-released TNFα and TGFβ Synergistically Enhance Cancer Cell Migration Directedness via the Induction of MMP-1 in Cancer Cells R. Li and R. Kamm 1

1

3:00PM

Artery Remodeling under Axial Twist in Three Day Organ Culture G. Wang1,2, A. Voorhees1, Y. Xiao1, Z-L. Jiang2, and H-C. Han1,2 University of Texas at San Antonio, San Antonio, TX, 2Shanghai Jiaotong University, Shanghai, China, People's Republic of

1

3:15PM

Structural Remodeling of the Bovine Aorta During Pregnancy S. Wells1, A. Prosterman1, A. MacKenzie1, and C. Van Iderstine1 1

Dalhousie University, Halifax, NS, Canada

Massachusetts Institute of Technology, Cambridge, MA

1

2:45PM

A 3D Microphysiological System of Tumor Tissue for Realistic Therapeutic Modeling A. Sobrino Gregorio1, D. Phan1, S. George2, and C. Hughes1,2 University of California, Irvine, Irvine, CA, 2The Edwards Lifesciences Center for Advanced Cardiovascular Technology, Irvine, CA

1

3:00PM

Speed Matters: Cadherin-11 Expressing Cancer Cells Hijack Fibroblasts for High-speed Invasion Z. Gu1,2, E. Tonkova2, Y-H. Hsu3, S. Alexander3, Z. Han3, M-C. Hung3, P. Friedl3, K. Konstantopoulos1, and M. Brenner2 Johns Hopkins University, Baltimore, MD, 2Harvard Medical School, Boston, MA, 3The University of Texas MD Anderson Cancer Center, Houston, TX

1

Track: Cellular and Molecular Bioengineering OP-Thurs-2-9 - Room 007C

Cell Adhesion and the Extracellular Matrix Interactions Chairs: Michael Smith, Jennifer Munson 2:00PM

A High-Throughput Array to Assess Dynamic, Intracellular Signaling Responses to Biomaterial-Mediated Adhesive and Mechanical Cues S. Seidlits1, B. Peñalver Bernabé2, S. Shin2, L. Broadbelt2, and L. Shea2 University of California Los Angeles, Los Angeles, CA, 2Northwestern University, Evanston, IL

1

3:15PM

2:15PM

D. LaValley1, B. Mason1, J. Huynh1, and C. Reinhart-King1

B. Hubbard1, J. Buczek-Thomas1, M. Nugent2, and M. Smith1

Matrix Stiffening Primes Increased Permeability in Tumor Vasculature in Response to Pro-Tumorigenic Extracellular Cues 1

Cornell University, Ithaca, NY

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

80

BMES 2014

Altered Biological Properties Result from Bond Breakage within Mechanically Stressed Fibronectin Fibers 1

Boston University, Boston, MA, 2University of Massachusetts, Lowell, Lowell, MA

2:00pM-3:30pm Platform Sessions Thurs-2

2014 | OCTOBER 23 | Thursday

2:30PM

Local ECM Alignment Directs Initial Cell Spreading To Promote Cell Migration In 3D S. Carey1, Z. Goldblatt1, and C. Reinhart-King1 1

Track: Nano to Micro Technologies OP-Thurs-2-11 - Room 008A

BioMEMS II

Cornell University, Ithaca, NY

2:45PM

Analysis of the Cytoskeleton and Mechanics of Migrating Cells in Engineered 3D Extracellular Matrix C. Choi1,2, B. Trappmann1,2, S. Alimperti1,2, D-H. Nguyen3, S. Stapleton3, and C. Chen1,2

Chairs: Rafael Davalos, Erkin Seker 2:00PM

Track Etched Magnetic Micropores to Efficiently Sort Rare Pathogens from Large Volume, Unprocessed Clinical and Environmental Samples

Boston University, Boston, MA, Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, 3University of Pennsylvania, Philadelphia, PA

M. Muluneh , W. Shang , and D. Issadore

3:00PM

2:15PM

1

2

Fibronectin Mechanics and Signaling in Epithelial to Mesenchymal Transition L. Griggs1, M. Zhao1, R. Malik 1, L. Elmore1, and C. Lemmon1 1

1

1

1

University of Pennsylvania, Philadelphia, PA

Multiplexed Free-standing Nanowire Transistor Bioprobe for Intracellular Recording: A General Fabrication Strategy Q. Qing1, L. Xu2, Z. Jiang2, and L. Mai3

Virginia Commonwealth University, Richmond, VA

Arizona State University, Tempe, AZ, 2Harvard University, Cambridge, MA, 3Wuhan University of Technology, Wuhan, China, People's Republic of

1

3:15PM

Focal Adhesion Complex Activity is Important for the Maintenance of Chondrogenic Phenotypes H. Shin1, M. Lee1, J. Choung 1, and J. Shin1 1

1

2:30PM

A Microdevice For Studying Intercellular Electromechanical Transduction In Adult Cardiac Myocytes X. Zhang1 and Y. Zhao1

KAIST, Daejeon, Korea, Republic of

1

Ohio State University, Columbus, OH

Track: Cellular and Molecular Bioengineering, Biomechanics OP-Thurs-2-10 - Room 007D

2:45PM

Mechanotransduction II

3:00PM

Measuring the Growth Rate of Cancerous Human Breast Cells E. Corbin1 and R. Bashir1 1

University of Illinois Urbana-Champaign, Urbana, IL

Chairs: Alesha Castillo, Nathan Sniadecki

Microfluidic Blood Sorting For Improved Blood Quality Over Prolonged Storage

2:00PM

S. Huang1, H. Hou1, T. Kanias2, J. Sertorio2, H. Chen3, M. Gladwin2, and J. Han1 MIT, Cambridge, MA, 2University of Pittsburgh, Pittsburgh, PA, 3Harvard School of Public Health, Boston, MA

Primary Cilia Under Ultrasound G. Budhiraja and A. Subramanian 1

1

1

1

University of Nebraska, Lincoln, NE

3:15PM

A Cell-based Fluid Shear Sensor

2:15PM

Molecular Targeting and Localized Mechanochemical Stimulation of ErbB Receptors with Fe-Au Nanorods D. Kilinc , A. Lesniak , S. Rashdan , D. Gandhi , A. Blasiak , P. Fannin , A. von Kriegsheim1, W. Kolch1, and G. Lee1 1

1

2

1

1

S. Varma1 and J. Voldman1 1

Massachusetts Institute of Technology, Cambridge, MA

3

2:30PM

Track: Nano to Micro Technologies, Cellular and Molecular Bioengineering OP-Thurs-2-12 - Room 008B

K. Beicker1, M. Falvo1, E. O'Brien III1, and R. Superfine1

Microfluidic Platforms II

University College Dublin, Dublin, Ireland, 2University of Bahrain, Manama, Bahrain, 3Trinity College Dublin, Dublin, Ireland

1

Sideways Microscopy for Viewing Nuclear Deformation 1

University of North Carolina at Chapel Hill, Chapel Hill, NC

2:45PM

Endothelial Cell Aging Elevates Traction Forces and Permeability T. Cheung1, J. Yan1, J. Huang1, F. Yuan1, and G. Truskey1 1

Duke University, Durham, NC

3:00PM

Investigation of T Cell Mechanosensing Using Microfabricated Elastomer Pillars W. Jin1, K. Bashour1, and L. Kam1 1

Columbia University, New York, NY

3:15PM

Chairs: John Slater, Jungkyu (Jay) Kim 2:00PM

Vortex-assist Electroporation for Combinatorial Drug Screenings D. Vickers1 and S. Hur1 1

Rowland Institute at Harvard University, Cambridge, MA

2:15PM

Aqueous Two-Phase System-Mediated Antibody Micropatterning for Multiplex Protein Biomarker Detection J. Frampton1,2, J. White2, A. Simon2, M. Tsuei2, S. Paczesny3, and S. Takayama2 Dalhousie University, Halifax, NS, Canada, 2University of Michigan, Ann Arbor, MI, 3Indiana University, Indianapolis, IN

1

The Effects Of Intermittent And Incrementally Increasing Strain Amplitude Cyclic Stretching On Collagen Production In Fibrin-Based Engineered Cardiovascular Tissues

2:30PM

J. Schmidt1 and R. Tranquillo1

G. Damhorst1, J. Kooiman1, R. Chaves1, M. Sobieraj1, T. Ghonge1, and R. Bashir1

1

University of Minnesota, Minneapolis, MN

A Microfluidic Virus Capture and Sensing Device for HIV Viral Load Measurements 1

University of Illinois at Urbana-Champaign, Urbana, IL

BMES 2014

81

Platform Sessions

Th-2

Thursday | OCTOBER 23 | 2014

Platform Sessions Thurs-2 2:00pM-3:30PM

2:45PM

KS-Detect: A Solar-Powered Smartphone-Based System for Diagnosing Kaposi's Sarcoma in Resource-Limited Settings L. Jiang1, A. Gardner1, Z. Lu1, G. Akar2, E. Cesarman2, and D. Erickson1 1

Cornell University, Ithaca, NY, 2Weill Cornell Medical College, New York, NY

3:00PM Platform Sessions

Th-2

Cell Affinity Chromatography And Electrical Measurements To Detect Cancer Cells In Microfluidics M. Islam1, M. Bellah1, Y-T. Kim1, and S. Iqbal1 1

3:15PM

Microfluidic Protein Encapsulation in Monodisperse Drug-based Polymer Microspheres W. Yu , M. Zheng , J. Zahn , and K. Uhrich 1

1

1

Spine Biomechanics Chairs: John Cotton, Teja Guda 2:00PM

Biomechanical Effects of Age-related Changes in Cartilaginous Endplates Morphology on Lumbar Discs

University of Texas at Arlington, Arlington, TX

1

Track: Biomechanics, Orthopaedic and Rehabilitation Engineering OP-Thurs-2-14 - Room 103B

1

Rutgers University, Piscataway, NJ

Track: Device Technologies and Biomedical Robotics, Cardiovascular Engineering OP-Thurs-2-13 - Room 201

Cardiovascular Devices: Intelligent Design Using Computations and Experiments

M. Hussain1 and C. DeGeer1 1

Logan University, Chesterfield, MO

2:15PM

Characterization of Cortical Bone Thickness Changes in the Thoracic Skeleton with Age and Gender S. Lynch1, A. Weaver1, and J. Stitzel1 Virginia Tech - Wake Forest University School of Biomedical Engineering and Sciences, Winston-Salem, NC

1

2:30PM

Laxity Of The Lumbar Spine N. Battaglia1, M. Mahfouz1,2, R. Komistek1,2, and C. Carr1 1

University of Tennessee, Knoxville, TN, 2Institute of Biomedical Engineering, Knoxville, TN

2:45PM

Chairs: Keefe Manning, James Antaki

A Finite Element Model of In Vivo Lumbar Facet Capsular Ligament Motion Based on Fluoroscopic Data from Healthy Subjects

2:00PM

A. Claeson1 and V. Barocas1 University of Minnesota, Minneapolis, MN

The Long and Strange Trip from Bench to Bedside: Lessons Learned from the Pediaflow Magnetically Levitated Rotodynamic Blood Pump

1

J. Antaki1

Effect Of Implant Design And Material On Subsidence Following Dynamic Loading of Intervertebral Devices

1

Carnegie Mellon University, Pittsburgh, PA

3:00PM

2:30PM

A. Valdevit1, P. Ullrich2, M. Gallagher3, and J. Schneider3

Cardiovascular Devices: From the Bench and Computer to the Bedside/Bassinet

1

A. Yoganathan1

3:15PM

1

Georgia Institute of Technology, Atlanta, GA

2:45PM

Cardiovascular Devices: From the Bench and Computer to the Bedside/Bassinet A. Yoganathan1 1

Georgia Institute of Technology, Atlanta, GA

3:00PM

Design Methodology for Blood Pumps K. Manning1,2, C. Siedlecki1,2, S. Deutsch1, and G. Rosenberg1,2 The Pennsylvania State University, University Park, PA, 2Penn State Hershey Medical Center, Hershey, PA

1

3:15PM

CFD-Based Multi-Objective Modeling of Artificial Lung Devices J. Zhang1, Z. Chen1, B. Griffith1, and Z. Wu1 1

University of Maryland School of Medicine, Baltimore, MD

Stevens Institute of Technology, Hoboken, NJ, 2NeuroSpine Center of Wisconsin, Appleton, WI, 3Titan Spine, LLC, Mequon, WI

Machine Learning Predicts Degenerative Pathology N. Battaglia1, M. Mahfouz1,2, R. Komistek1,2, and C. Carr1 1

University of Tennessee, Knoxville, TN, 2Institute of Biomedical Engineering, Knoxville, TN

Track: Bioinformatics, Computational and Systems Biology OP-Thurs-2-15 - Room 202A

Multiscale Modeling Chairs: Stacey Finley, Heather Hayenga 3:00PM Invited

Agent Based Model for Predicting Angiogenic Sprout Frequency and Location in 3D Culture J. Walpole1, J. Chappell2, J. Cluceru2, F. Mac Gabhann3, V. Bautch2, and S. Peirce1 University of Virginia, Charlottesville, VA, 2University of North Carolina Chapel Hill, Chapel Hill, NC, 3Johns Hopkins University, Baltimore, MD

1

2:30PM

A Whole-body PKPD Model for Multimodal Reversal of Cardiotoxicity by Intravenous Lipid Dispersions B. Akpa1 1

University of Illinois at Chicago, Chicago, IL

2:45PM

Multiscale Model of Lung Inflammation P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

82

BMES 2014

R. Pidaparti1, R. Heise2, R. Cooper2, T. Rolle2, and A. Reynolds2 1

University of Georgia, Athens, GA, 2Virginia Commonwealth University, Richmond, VA

2:00pM-3:30pm Platform Sessions Thurs-2

2014 | OCTOBER 23 | Thursday

3:00PM

Modeling Blood Flow Control in the Kidney A. Ford Versypt1, J. Arciero2, L. Ellwein3, E. Makrides4, and A. Layton5 Oklahoma State University, Stillwater, OK, 2Indiana University-Purdue University Indianapolis, Indianapolis, IN, 3Virginia Commonwealth University, Richmond, VA, 4Brown University, Providence, RI, 5Duke University, Durham, NC

1

Track: Biomedical Imaging and Optics OP-Thurs-2-17 - Room 203A

Molecular Probes I Chairs: Aaron Mohs, Efstathios Karathanasis

3:15PM

Comprehensive Computational Analysis of Tissue Remodeling in the Rat Brain After Traumatic Injury

2:00PM

K. Grama1, M. Megjhani1, Y. Lu1, B. Roysam1, J. Redell2, P. Dash2, and D. Maric3

Z. Cheng1, C. Aspinwall2, and A. tsourkas1

University of Houston, Houston, TX, 2University of Texas Health Science Center at Houston, Houston, TX, 3National Institute of Neurological Disorders and Stroke, Bethesda, MD 1

Platform Sessions

Th-2

Stabilized Paramagnetic Porousliposomes 1

University of Pennsylvania, philadelphia, PA, University of Arizona, Tucson, AZ 2

2:15PM

Genetically Encoded MRI Sensor of ATP

Track: Orthopaedic and Rehabilitation Engineering, Biomedical Imaging and Optics OP-Thurs-2-16 - Room 202B

G. Sun1, A. Mukherjee2, X. Zhang2, D. Schaffer1, and M. Shapiro2 University of California, Berkeley, Berkeley, CA, 2California Institute of Technology, Pasadena, CA

1

2:30PM

Musculoskeletal Imaging

Single-Molecule Tracking Using Different Fluorescent Labels C. Liu1, Y-L. Liu1, E. Perillo1, Q. Zhuang1, and H-C. Yeh1

Chairs: Andrew Anderson , Jeff Weiss

1

3:00PM Invited

2:45PM

3D Dual Echo Steady State (DESS) MRI Accurately Quantifies Acetabular Cartilage Thickness C. Abraham1, N. Bangerter2, L. McGavin1, C. Peters1, A. Drew1, C. Hanrahan1, and A. Anderson1 1

University of Texas at Austin, Austin, TX

Development of ROS Ratiometic Optical Nanoprobes for In Vivo Imaging of Wound Inflammation J. Zhou1, H. Weng1, A. Nair1, W. Hu2, and L. Tang1 1

University of Utah, Salt Lake City, UT, 2Brigham Young University, Provo, UT

University of Texas at Arlington, Arlington, TX, 2Progenitec, Arlington, TX

2:15PM

3:00PM

Impaired Muscular Loading During Post-natal Growth Leads to Altered Structure of the Developing Murine Hip

An Activatable Nanoparticle Probe for Molecular Imaging of Protease Activity by Dual Energy CT

C. Ford1, S. Thomopoulos1, and M. Killian1

J. Ashton1, C. Badea2, and J. West1

1

1

Washington University, St Louis, MO

Duke University, Durham, NC, 2Duke University Medical Center, Durham, NC

2:30PM

3:15PM

Near Infrared Optical Imaging of Bone Cell Activity and Skeletal Drug Delivery

An EDB Fibronectin Specific Peptide Probe for Molecular Imaging of Cancer EMT

K. Kozloff1

Z. Han1, M. Gujrati1, Z. Zhou1, X. Shi1, and Z. Lu1

1

1

University of Michigan, Ann Arbor, MI

Case Western Reserve University, Cleveland, OH

2:45PM

Can Extended Field-of-View Ultrasound Imaging Be Used to Measure Differences in Upper Extremity Fascicle Lengths? C. Nelson , , J. Dewald , and W. Murray , , 1 2

1 3

1

1 2 3

Teaching in a Flipped Classroom

Northwestern University, Chicago, IL, 2Rehabilitation Institute of Chicago, Chicago, IL, Edward Hines, Jr. VA Hospital, Hines, IL

Chairs: Matthew Glucksberg, Donald Gaver

3:00PM

Use of Portable Ultrasound to Measure Dynamic Motion of Cervical Spine Ex-Vivo and In-Vivo M. Zheng1,2, A. Masoudi2, D. Buckland2,3, T. Szabo1, and B. Snyder2,4 Boston University, Boston, MA, 2Beth Israel Deaconess Medical Center, Boston, MA, Massachusetts Institute of Technology, Cambridge, MA, 4Boston Children's Hospital, Boston, MA

3

Integration of Video Demonstrations into an Undergraduate Tissue Culture Laboratory Course 1

Rice University, Houston, TX

2:15PM

3:15PM

Contrast-enhanced Characterization of Intervertebral Disc Degeneration using Equilibrium Partitioning of an Ionic Contrast Agent Micro Computed Tomography (EPIC)-µCT T. Maerz , K. Kristof , M. Newton , O. Motovylyak , J. Fischgrund , D. Pakr , and K. Baker1 1

2:00PM

A. Saterbak1, B. Ghosn1, and M. Wettergreen1

1

1

Track: Biomedical Engineering Education (BME) OP-Thurs-2-18 - Room 203B

1

1

William Beaumont Hospital, Royal Oak, MI

1

1

Implementation and Assessment of Flipped Classroom Paradigm in Biomedical Engineering Course J-M. Maarek1, A. Ayiotis1, and G. Ragusa1 1

1

University of Southern California, Los Angeles, CA

2:30PM

Expected and Unexpected Barriers to Learning in a Flipped Biotransport Course S. Williams-Duncan1 and B. Helmke1 1

University of Virginia, Charlottesville, VA

2:45PM

Efficacy of Simple, Flipped Classroom Techniques in Biomedical Engineering Education: Comparative Analysis of Traditional and Flipped Biofluid Mechanics Course J. Lippmann1 1

University at Buffalo, State University of New York, Buffalo, NY

BMES 2014

83

Thursday | OCTOBER 23 | 2014

Platform Sessions Thurs-2 2:00pM-3:30PM

SPECIAL SESSION

SPECIAL SESSION

2:00 PM – 6:00 PM Room 004

2:00 PM – 3:30 PM Room 204A

BMES-NSF Special Session on Research in Biomedical Engineering and Grant Writing

Overcoming Challenges and Obstacles for Clinical Translation: From Bench to Bedside

(Pre-Registration Required)

BMES and the National Science Foundation (NSF) will convene a special session focusing on innovative research in biomedical engineering and grant writing. The session will bring together NSF Bioengineering and Engineering Healthcare grantees, young investigators, junior and senior faculty, post-doctoral fellows and graduate students for idea exchange and networking related to conducting and funding cutting-edge research in BME. The session will showcase NSF funded research and researchers, foster collaboration and idea exchange, familiarize participants with NSF funding mechanisms, and provide strategies for preparing competitive grant proposals, in particular, NSF CAREER grant applications. The research areas where the NSF Biomedical Engineering Program supports fundamental and transformative research will also be discussed. Participants at all levels will gain an increased awareness of NSF funded research, a better understanding of NSF funding opportunities and how to prepare successful grant applications, and a chance to establish new relationships leading to future collaborations. This material is based upon work supported by the National Science Foundation under Grant No. CBET – 1444074.

The panel session will cover a broad range of issues related to translating research findings to the clinic. The four panelists are at different stages of the process and have different approaches to addressing clinical unmet needs. Each panelist will describe their experiences and decision making processes to stimulate discussion with the audience regarding strategies on how to overcome barriers for translation. panelists: Ed Damiano (Boston University)

“A Bionic Pancreas for Type 1 Diabetes Management” Inspired by his son’s diabetes, Dr. Damiano has developed the world’s first fully autonomous bihormonal bionic pancreas, which is currently in clinical trials. Damiano hopes to complete clinical trials by the end of 2016 and submit the device for FDA approval by 2017. Mauris N DeSilva (Naval Medical Research Unit San Antonio)

“Novel Strategies for Prevention of Infections Post Cranioplasty” Dr. DeSilva›s research focuses on novel prophylactic strategies for postoperative infections following cranioplasty to treat traumatic head injuries such as those seen in the recent conflicts in Iraq and Afghanistan. Catherine Klapperich (Boston University)

“Low Cost Diagnostics for Cancer and Infectious Disease”Dr. Klapperich has developed several technologies for minimally instrumented diagnostics. Her technology is the basis for a new startup company Micro Analysis Integration (Los Angeles, CA). Christine Schmidt (University of Florida)

“Regenerating Nerve Tissue and Managing Scar Tissue in Wound Healing” Dr. Schmidt’s development of decellularized nerve tissue (licensed and utilized in AxoGen (Alachua, FL) Inc.’s AVANCE™ nerve graft) has impacted thousands of patients who suffer from peripheral nerve injuries. Dr. Schmidt’s technology is also the basis for a start-up company Alafair Biosciences (Austin,TX) that develops cross-linked polysaccharide hydrogel films to address postsurgical adhesions. Sponsored by

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

84

BMES 2014

4:30PM - 6:00PM Platform Sessions Thurs-3

THURSDAY, October 23, 2014

2014 | OCTOBER 23 | Thursday

4:45PM

Towards Controlling Chondrogenesis using Novel Thermo-Sensitive Hydrogels

4:30 PM - 6:00 PM PLATFORM SESSIONS – Thurs - 3

O. Baruti1, L. Bonassar2, and J. Mendenhall1 1

Morehouse College, Atlanta, GA, 2Cornell University, Ithaca, NY

Track: Tissue Engineering, Biomaterials OP-Thurs-3-1 - Room 001A

5:00PM

Hepatic, Pancreatic, Digestive and Renal Tissue Engineering

C. Addington1, C. Millar-Haskell1, J. Heffernan1, R. Sirianni2, and S. Stabenfeldt1

Development of a Hyaluronic Acid-Laminin Hydrogel to Increase Neural Stem Cell Response to SDF-1α Arizona State University, Tempe, AZ, 2St. Joseph's Hospital and Medical Center, Phoenix, AZ

1

Chairs: Salman Khetani, Sundararajan Madihally

5:15PM

4:30PM

Poly(thioketal) polymers and their use in the formation of hydrophobic and hydrophilic cell-degradable tissue engineering scaffolds

Encapsulation of Beta Cells Within Ligand Functionalized Scaffolds Improve Insulin Secretion Function

J. Martin1, M. Gupta1, J. Page1, F. Yu1, J. Davidson1, S. Guelcher1, and C. Duvall1

S. Kizilel1, T. Bal1, and G. Cinay1 1

KOC University, Istanbul, Turkey

1

4:45PM

5:30PM

CD31 Antibody Conjugation Improves Re-endothelialization of Acellular Kidney Scaffolds for Whole Organ Engineering

Fabrication Of Poly(ε-caprolactone) Scaffolds With Nanofibrous Chitosan Networks

I. Ko1, M. Abolbashari1, J. Huling1, J. Zambon 1, C. Kim1, G. Orlando1, M. Moradi1, T. AbouShwareb1, J. Jackson1, A. Atala1, and J. Yoo1 1

X. Jing1,2, T. Cordie1,3, M. Salick1,4, and L-S. Turng1,2 Wisconsin Institutes for Discovery, University of Wisconsin, Madison, WI, 2Department of Mechanical Engineering, University of Wisconsin, Madison, WI, 3Department of Biomedical Engineering, University of Wisconsin, Madison, WI, 4Department of Engineering Physics, University of Wisconsin, Madison, WI 1

Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC

5:00PM

Long Term Co-culture Strategies for Primary Hepatocytes and Liver Sinusoidal Endothelial Cells

5:45PM

Synthesis and Cell Attachment Evaluation of Hybrid Materials with Peptide-Synthetic Polymer-Silica

S. Bale , I. Golberg , R. Jindal , W. McCarty , M. Luitje , M. Hegde , A. Bhushan1, O. Usta1, and M. Yarmush1 1

1

1

1

1

Vanderbilt University, Nashville, TN

1

Y. Hirano1, A. Hattori1, A. Terada1, and S. Fujii2

Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School and Shriners Burns Hospital, Boston, MA

1

1

Kansai University, Suita, Japan, 2Osaka Institute of Technology, Osaka, Japan

5:15PM

Dynamic Interplay of Flow and Collagen Stabilizes Primary Hepatocytes in a Microfluidic Platform A. Bhushan , , M. Hegde , , R. Jindal , , S. Bale , , W. McCarty , , I. Goldberg , B. Usta1,2, and M. Yarmush1,2 1 2

1

1 2

1 2

1 2

1 2

Massachusetts General Hospital, Boston, MA, 2Harvard Medical School, Boston, MA

5:30PM

A 3D Microfluidic Human Liver-on-a-chip as a Physiological Model of Liver Acinus A. Bhushan1,2, R. Jindal1,2, L. Prodanov1,2, S. Bale1,2, M. Hegde1,2, W. McCarty1,2, I. Goldberg1, B. Usta1,2, and M. Yarmush1,2 1

Massachusetts General Hospital, Boston, MA, 2Harvard Medical School, Boston, MA

1

Track: Biomaterials OP-Thurs-3-3 - Room 006A

Therapeutic and Theranostic Biomaterials II Chairs: Srivatsan Kidambi, Aaron Baker 4:30PM

Engineering a Multipurpose "Virus Trap and Safety Net" Microbicide S. Aniagyei1 and J. Steinbach1 1

5:45PM

A Biomimetic PEG Hydrogel to Create Liver-Specific Vasculature and Evaluate Hepatocyte Bioactivity H. Bearat1, S. Higbee2, and J. West1 1

Duke University, Durham, NC, 2Rice University, Houston, TX

5:00PM

Syndesomes-Based Therapeutic for Enhanced Wound Healing in Diabetic Mice S. Das1, G. Singh1, M. Martinez1, A. Dunn1, and A. Baker1 1

Track: Tissue Engineering, Biomaterials OP-Thurs-3-2 - Room 001B

University of Louisville, Louisville, KY

University of Texas, Austin, Austin, TX

5:15PM

Photo-Carbon Monoxide Releasing Molecules within Electrospun Meshes for Engineering Vascular Grafts

Scaffolds and Surfaces for Tissue Engineering II

E. Michael1, N. Abeyrathna1, K. Birthare1, Y. Liao1, and C. Bashur1

Chairs: Joseph Freeman, Edward Botchwey

Incorporation of the Anti-Cancer Agent Tannic Acid Into Biomaterials Used For Breast Reconstruction

4:30PM

Micro-Patterning Directional ECM Cues in Hydrogel-based Scaffolds for Cardiac Tissue Engineering Q. Jallerat and A. Feinberg 1

1

1

Florida Institue of Technology, Melbourne, FL

5:30PM

H. Shah1, J. Park1, B. Inskeep1, T. Ngobili1, K. Burg1, and B. Booth1 1

Clemson University, Clemson, SC

1

Carnegie Mellon University, Pittsburgh, PA

BMES 2014

85

Platform Sessions

Th-3

Thursday | OCTOBER 23 | 2014

Platform Sessions Thurs-3 4:30PM - 6:00PM

5:45PM

Multifunctional Unimolecular Micelles Loaded With the Anti-cancer Drug Aminoflavone for Triple Negative Breast Cancer Therapy G. Chen1, A. Brinkman2,3, N. Sherer2, W. Xu2,3, and S. Gong1,4 Materials Science Program and Wisconsin Institute for Discovery, University of Wisconsin– Madison, Madison, WI, 2McArdle Laboratory for Cancer Research, University of Wisconsin– Madison, Madison, WI, 3Molecular and Environmental Toxicology Center, University of Wisconsin–Madison, Madison, Madison, WI, 4Department of Biomedical Engineering, University of Wisconsin–Madison, Madison, Madison, WI

1

Track: Drug Delivery, Tissue Engineering OP-Thurs-3-5 - Room 006C

Drug Delivery in Tissue Engineering II Chairs: Piyush Koria, Joel D Bumgardner 4:30PM

Modeling Local Drug Delivery Near Orthopaedic Implants Platform Sessions

Th-3

Track: Biomaterials, Cellular and Molecular Bioengineering OP-Thurs-3-4 - Room 006B

Biomaterials for Controlling Cell Environment II Chairs: Janet Zoldan, Meng Deng 4:30PM

Interplay of Material Stiffness and Protein Tethering in Mechanically Based Differentiation A. Engler1,2 1

Dynamic Modulation Of Myofibroblast/Osteoblast Differentiation And Biomechanical Remodeling By Valve Interstitial Cells By Initial Tissue Stiffness B. Duan1, Z. Yin2, L. Hockaday1, R. Magin2, and J. Butcher1 Cornell University, Ithaca, NY, 2University of Illinois at Chicago, Chicago, IL

5:00PM

Physical Stabilization for the Viable Preservation of Whole Blood K. Wong1, R. Sandlin1, T. Carey1, A. Khankhel1, A. Shank1, J. Walsh1, D. Irimia1, S. Maheswaran1, D. Haber1, S. Stott1, and M. Toner1 1

Massachusetts General Hospital, Harvard Medical School, Charlestown, MA

5:15PM

Characterization of Mechanical/Chemical Properties of Calcium Responsive Composite Hydrogels and Assessment of Astrocytic Response C. McKay1, C. Johnson1, R. Pomrenke1, N. Schaub1, E. DeSimone1, J. McLane1, L. Ligon1, and R. Gilbert1 1

Rensselaer Polytechnic Institute, Troy, NY

5:30PM

Engineered Fibrillar Microenvironments for the Study of Mesenchymal Stem Cell Mechanosensing B. Baker1, B. Trappmann1, A. Nair2, I. Kim2, J. Burdick2, V. Shenoy2, and C. Chen1 1

Boston University, Boston, MA, 2University of Pennsylvania, Philadelphia, PA

5:45PM

Dynamic Photo-Tunable Hydrogels for Temporal Control of Stiffness R. Stowers1 and L. Suggs1 1

1

University of Texas at Austin, Austin, TX

Arizona State University, Tempe, AZ, 2Banner Good Samaritan Medical Center, Phoenix, AZ

4:45PM

Ultrasonic and Physical Characterizations of Acoustically Responsive Scaffolds A. Moncion1, K. Arlotta1, O. Kripfgans1, P. Carson1, J. Fowlkes1, and M. Fabiilli1 1

University of Michigan, Ann Arbor, MI

5:00PM

Synthesis of Cell Penetrating Peptides (CPPs) for Drug Delivery Applications G-W. Jin1, F. Ghasemi Tahrir1, W. Ma1, G. Cidonio1, and W. Suh1 1

UC San Diego, La Jolla, CA, 2Sanford Consortium for Regenerative Medicine, La Jolla, CA

4:45PM

1

M. Giers1, R. McLemore2, A. McLaren2, and M. Caplan1

Temple University, Philadelphia, PA

5:15PM

Growth Factor Delivery Through Synthetic Fibrin-Mimetic Matrix Promotes Wound Healing P. Briquez1, M. Martino2, and J. Hubbell1 Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 2Osaka University, Osaka, Japan

1

5:30PM

Long Term Doxycycycline Release to Prevent Infection and MMP Mediated Cellular Invasion in Implantable Biomaterials. E. Rivera-Delgado1 and H. von Recum1 Case Western Reserve University, Cleveland, OH

1

5:45PM

Delivery of siRNA from Fibrin Hydrogels for mRNA Knockdown of the BMP-2 Antagonist Noggin C. Kowalczewski1,2 and J. Saul1 Miami University, Oxford, OH, 2Virginia Tech-Wake Forest University, Winston-Salem, NC

1

Track: Biomechanics, Cardiovascular Engineering OP-Thurs-3-6 - Room 006D

Heart Valve Biomechanics Chairs: Jiro Nagatomi,Yi Hong 4:30PM

Quantification and Simulation of the Mechanical Roles of Collagen and Elastin in Mitral Valve Leaflets W. Zhang1, C. Carruthers2, J. Liao3, and M. Sacks1 University of Texas at Austin, Austin, TX, 2Medtronics, Pittsburgh, PA, 3Mississippi State University, Starkville, MS

1

4:45PM

Biomechanical Analysis of Transcatheter Valve Migration in PatientSpecific Models M. Bianchi1, T. Claiborne1, G. Marom1, R. Ghosh1, D. Bluestein2, M. Poon3, M. Musani4, E. Feldmann4, L. Gruberg4, H. Fernandez4, and J. Taylor Jr.4 Stony Brook University, StonyBrook, NY, 2Stony Brook University, Stony Brook, NY, 3Stony Brook Medicine, StonyBrook, NY, 4Stony Brook Medicine, Stony Brook, NY

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

86

BMES 2014

4:30PM - 6:00PM Platform Sessions Thurs-3

2014 | OCTOBER 23 | Thursday

5:00PM

Bending Properties Of Porcine Mitral, Tricuspid, Aortic, And Pulmonary Valve Leaflets B. Brazile1, B. Wang1, G. Wang1, R. Bertucci1, R. Prabhu1, S. Patnaik1, J. Butler1, A. Claude1, E. Brinkman-Ferguson1, L. Williams1, and J. Liao1 1

Mississippi State University, Mississippi State, MS

5:15PM

Track: Cardiovascular Engineering, Biomechanics OP-Thurs-3-8 - Room 007B

Cardiovascular Flow Modeling in Health and Disease

An Inverse Modeling-Based Diagnostic Tool for Heart Valves Leaflets Biomechanical Properties

Chairs: Robert Peattie, Wei Yin

A. Aggarwal1 and M. Sacks1

CFD Analysis of Cerebral Sidewall Aneurysm Hemodynamics

1

University of Texas at Austin, Austin, TX

J. Lindsay1, P. Nair1, H. Babiker1, J. Ryan1, and D. Frakes1

5:30PM

1

Image-based Immersed Boundary/Finite Element Model of the Human Mitral Valve X. Ma , H. Gao , N. Qi , C. Berry , B. Griffith , , and X. Luo 1

1

2

1

3 4

1

University of Glasgow, Glasgow, United Kingdom, 2University of Glasgow, glasgow, United Kingdom, 3University of North Carolina at Chapel Hill, Chapel Hill, NC, 4University of North Carolina School of Medicine, Chapel Hill, NC 1

Platform Sessions

Arizona State University, Tempe, AZ

Th-3

4:45PM

Computational Analysis of Low-Porosity Stent Effects on Idealized Sidewall Aneurysms D. DeJeu1, P. Nair1, H. Babiker1, J. Ryan1, and D. Frakes1 1

Arizona State University, Tempe, AZ

5:00PM

5:45PM

Turbulent Eddy Properties from CFD and Hemolysis Re-examined M. Ozturk1, E. O'Rear III1, and D. Papavassiliou1 1

4:30PM

High Resolution Immersed Boundary-finite Element Models of the Native and Prosthetic Aortic Root V. Flamini1, A. DeAnda2, and B. Griffith3

University of Oklahoma, Norman, OK

New York University Polytechnic School of Engineering, Brooklyn, NY, 2New York University School of Medicine, New York, NY, 3University of North Carolina at Chapel Hill, Chapel Hill, NC

1

Track: Cancer Technologies OP-Thurs-3-7 - Room 007A

5:15PM

Aortic Blood Flow Simulations in Turner Syndrome Patient and Agematched Control

Tumor Microenvironment II

W. Stoddard1, G. Mylavarapu1, E. Gutmark1, and I. Gutmark-Little2

Chairs: Adrian Shieh, Michelle Berny-Lang

University of Cincinnati, Cincinnati, OH, 2Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

1

4:30PM

Combining Peripheral Vaccination with Microenvironment Immunomodulation: A Two-Pronged Approach for Cancer Immunotherapy

5:30PM

P. Pradhan , J. Leleux , J. Liu , H. Qin , L. Kwak , and K. Roy

E. Pallares1, S. Kudernatsch1, S. Nidadavolu2, and D. Peterson1

1

1

1

1

2

2

1

Georgia Institute of Technology, Atlanta, GA, 2M. D. Anderson Cancer Center, Houston, TX

4:45PM

Contact Inhibition of Locomotion in a Fibrillar-like Microenvironment D. Milano and A. Asthagiri 1

1

1

Northeastern University, Boston, MA

5:00PM

3D Glioma Platform for Therapy-Resistant Cell Targeting Using High Frequency Electric Fields

Determining the Influence of Aneurysm Geometry and Location on Flow through a Carotid Bifurcation 1

University of Connecticut Health Center, Farmington, CT, 2CD-adapco, Melville, NY

5:45PM

A Unified Computational Tool for Patient-Specific Hemodynamics --from radiological images to in vivo flow structure in human arteries H. Yu1, Z. Wang2, C. Zhang3, N. Chen1, A. Sawchuk 4, Y. Zhao2, Y. Cheng3, and M. Dalsing4 Indiana University-Purdue University Indianapolis, Indianapolis, IN, 2Kent State University, Kent, OH, 3Wuhan University, Wuhan, China, People's Republic of, 4School of Medicine, Indiana University, Indianapolis, IN

1

J. Ivey1, M. Sano2, I. Nakano3, R. Davalos1, and S. Verbridge1 1 Virginia Tech, Blacksburg, VA, 2Stanford University School of Medicine, Stanford, CA, 3Ohio State University, Columbus, OH

5:15PM

Integrin Expression and Phenotype Predict Breast Cancer Metastasis L. Barney1, E. Dandley2, L. Jansen1, and S. Peyton1 University of Massachusetts, Amherst, Amherst, MA, 2North Carolina State University, Raleigh, NC

1

5:30PM

Malignant Melanoma Cells Assemble a Tumor Biofilm That Promotes Survival and Resistance in Response to Drug Treatment A. Afasizheva1, Y. Kotobuki1, H. Tillman1, W. Vieira1, K-L. Fung1, E. Chen2, and K. Tanner1 National Cancer Institute, Bethesda, MD, 2Columbia University, Stony Brook, NY

1

Track: Cellular and Molecular Bioengineering OP-Thurs-3-9 - Room 007C

Cell Interactions with the Extracellular Matrix Chairs: Mehdi Nikkhah, Adrian Shieh 4:30PM

Hydrogels with Tunable Stress Relaxation Properties to Regulate Stem Cell Fate O. Chaudhuri1, L. Gu2, D. Klumpers2, M. Darnell2, S. Bencherif2, J. Weaver2, N. Huebsch3, and D. Mooney2 Stanford University, Stanford, CA, 2Harvard University, Cambridge, MA, 3UCSF gladstone Institute, San Francisco, CA

1

5:45PM

Bioreactor-derived Fluid Flow Promotes Epithelial-to-Mesenchymal Transition in Breast Cancer Cells K. Fuh1, B. Kooistra1, R. Shepherd1, and K. Rinker1 University of Calgary, Calgary, AB, Canada

1

4:45PM

Orthogonal patterning of matrix stiffness and ligand density for highthroughput stem cell mechanobiology A. Rape1, M. Zibinsky1, N. Murthy1, and S. Kumar1 1

University of California, Berkeley, Berkeley, CA

BMES 2014

87

Platform Sessions Thurs-3 4:30PM - 6:00PM

Thursday | OCTOBER 23 | 2014

5:00PM

5:45PM

H. Yang1, T. Borg2, and B. Gao1

C. DuFort1, J. Rys2, M. Baird3, M. Davidson3, and T. Alliston1

Relationship Between Basement Membrane Development and Sarcomerogenesis on Single Cardiomyocyte 1

Quantifying the Dynamics and Spatial Organization of TGFβ receptors with Single Particle Tracking Photoactivated Localization Microscopy

Clemson University, Clemson, SC, 2Medical University of South Carolina, Charleston, SC

5:15PM

Platelets Use Glycoprotein Ib-IX-V Complex to Squeeze Tight onto VWF S. Feghhi1, A. Munday2, W. Tooley1, S. Rajsekar1, J. Lopez1,2, and N. Sniadecki1 University of Washington, Seattle, WA, Puget Sound Blood Center, Seattle, WA

1

Platform Sessions

Th-3

2

5:30PM

UCSF, San Francisco, CA, 2UC Berkeley - UCSF, San Francisco, CA, 3Florida State University, Tallahassee, FL

1

Track: Nano to Micro Technologies, Translational Biomedical Engineering OP-Thurs-3-11 - Room 008A

Mechanical Signaling in Keratinocyte Colony Formation

Paper Fluidics

H. Zarkoob1, J. Selby1, S. Ponnaluri1, K. Messingham1, J. Fairley1, and E. Sander1

Chairs: Jungkyu (Jay) Kim, Daniel Ratner

University of Iowa, Iowa City, IA

4:30PM

1

Simultaneously Concentrating And Detecting Biomarkers On Paper

5:45PM

R. Chiu1, E. Jue1, A. Yip1, A. Berg1, S. Wang1, A. Kivnick1, P. Nguyen1, and D. Kamei1

Mechanical Analysis of Rat Trabecular Meshwork J. Huang1, L. Camras1, and F. Yuan1

1

Duke University, Durham, NC

1

UCLA, Los Angeles, CA

5:00PM

Track: Cellular and Molecular Bioengineering, Bioinformatics, Computational and Systems Biology OP-Thurs-3-10 - Room 007D

Engineering Cells and Pathways via Synthetic and Systems Biology

K. Haynes , C. Hom , B. Damadzadeh , and D. Barclay

University of Houston, Houston, TX, 2Baylor College of Medicine, Houston, TX

5:15PM

Paper-Based Diagnostic for Influenza A Detection University of Washington, Seattle, WA, 2Oregon State University, Corvallis, OR

5:30PM

Epigenetic Engineering of Human Cells with DNA-packing Actuators and Sensors 1

1

1

4:30PM

1

N. Piety1, X. Yang1, B. Dinu2, A. George2, and S. Shevkoplyas1

C. Holstein1, S. Bennett1, E-M. Strauch1, A. Chevalier1, E. Fu2, D. Baker1, and P. Yager1

Chairs: Karmella Haynes, Feilim Mac Gabhann

1

Paper-based Assay for Point-of-care Quantification of HbS Content in Blood of Sickle Cell Disease Patients

1

Purification and Concentration of Nucleic Acids in Porous Membranes for Point-of-Care Applications S. Byrnes1, J. Bishop1, L. Lafleur1, J. Buser1, B. Li2, C. Olsen2, B. Lutz1, and P. Yager1 1

Arizona State University, Tempe, AZ

1

University of Washington, Seattle, WA, 2GE Global Research Center, Niskayuna, NY

5:45PM

4:45PM

Targeting HBV DNA With CRISPR/Cas Leads to cccDNA Destruction in Infected Cells V. Ramanan1, D. Cox1, A. Shlomai2, R. Schwartz1, C. Rice2, F. Zhang1,3, and S. Bhatia1,4,5 Massachusetts Institute of Technology, Cambridge, MA, 2The Rockefeller University, New York, NY, 3Broad Institute, Cambridge, MA, 4Brigham and Women's Hospital, Boston, MA, 5 Howard Hughes Medical Institute, Cambridge, MA

Bacterial Cell Filtration, Amplification, and Detection in Paper Matrices for Molecular Diagnostics at the Point of Care J. Linnes1, C. Ellenson1, and C. Klapperich1 1

Boston University, Boston, MA

1

5:00PM

Track: Nano to Micro Technologies, Cellular and Molecular Bioengineering OP-Thurs-3-12 - Room 008B

A. Keung1, C. Bashor1, S. Kiriakov2, J. Collins1,3, and A. Khalil2

Microfluidic Platforms III

Boston University/HHMI, Boston, MA, 2Boston University, Boston, MA, 3Wyss Institute for Biologically Inspired Design, Boston, MA

Chairs: Anand Ramasubramanian, Leo Wan

5:15PM

4:30PM

J. Sun1, J. Townson2, Y-S. Lin2, B. Kaehr3, C. Brinker2, Y. Wang4, and E. Jakobsson1

S. Gulati1, W. Good1, K. Vijayakumar2, W. Tamayo1, X. Niu3, J. Edel2, and A. deMello4

Synthetic Chromatin-Based Transcriptional Logic, Spatial Genomic Regulation, And Memory 1

Influence of Microfluidic Geometry on Micro-droplet formation

Protocells as a Platform for Bottom-up Synthetic Biology University of Illinois at Urbana Champaign, Urbana, IL, 2University of New Mexico, Albuquerque, NM, 3Sandia National Lab, Albuquerque, NM, 4University of California San Diego, La Jolla, CA

1

4:45PM

5:30PM

Novel Divalent Aptamer Assembly For Controlled VEGF Receptor Activation V. Ramaswamy , A. Monsalve , B. Dollinger , J. Dobson , and J. Allen 1

1

1

University of Florida, Gainesville, FL

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

88

University of the Pacific, Stockton, CA, 2Imperial College London, London, United Kingdom, 3University of Southampton, Southampton, United Kingdom, 4ETH Zürich, Zürich, Switzerland

1

BMES 2014

1

1

1

MECs: Microfluidic "Building Blocks" for Custom Bioinstruments D. Hill1, L. Anderson1, C. Hill1, and W. Grover1 1

University of California, Riverside, Riverside, CA

4:30PM - 6:00PM Platform Sessions Thurs-3

2014 | OCTOBER 23 | Thursday

5:00PM

Inertial Focusing in Curved Channels: Towards Precision Biofluid Processing J. Martel1 and M. Toner1 1

Massachusetts General Hospital, Charlestown, MA

5:15PM

Using Nanoporous Silicon Nitride Membranes as Electro-osmotic Pumps and Nanofluidic Transistors K. Smith1 and J. McGrath1 1

Chairs: Joel Stitzel, Andrew Kemper

Head Injury Risk In Oblique Frontal Motor Vehicle Crashes R. Chen1 and H. Gabler1

On-chip Fingerprinting Surface Enhanced Raman Scattering (SERS) Spectra Of Living Cells Via [email protected] Nanocomplex Fabricated By Optothermal Effect Y. Xie1 and T. Huang1 The Pennsylvania State University, University Park, PA

1

Platform Sessions

Virginia Tech, Blacksburg, VA

Th-3

4:45PM

Assessment of Angular Rate Sensors to Measure Rotational Head Acceleration during Impact Testing S. Rowson1, R. Daniel1, B. Cobb1, and S. Duma1 1

5:45PM

Flexible Microfluidic Device with Microporous Walls for Perfusion Cell Culture C. Chan1, V. Goral2, M. DeRosa2, T. Huang1, and P. Yuen2 1

Methods for Assessing Injury and Injury Risk 4:30PM

University of Rochester, Rochester, NY

5:30PM

1

Track: Biomechanics OP-Thurs-3-14 - Room 103B

Pennsylvania State University, University Park, PA, Corning Incorporated, Corning, NY 2

Virginia Tech, Blacksburg, VA

5:00PM

Methods for Studying Brain Motion During Head Impact in a Gottingen Minipig Model A. Hermundstad1, E. Fievisohn1, P. VandeVord1, C. Untaroiu1, and W. Hardy1 1

Virginia Polytechnic and State University, Blacksburg, VA

Track: Device Technologies and Biomedical Robotics OP-Thurs-3-13 - Room 201

5:15PM

Medical Device Technologies



Chairs: Kevin Soucy, Chander Sadasivan

5:30PM

Rotational Moment Of Inertia Improves Predictions Of Axonal Injury L. Atlan1, S. Sullivan1, and S. Margulies1 1

University of Pennsylvania, Philadelphia, PA

Injury Risk Curves for Specific Injuries and Body Regions in Frontal Motor Vehicle Crashes

4:30PM

Laser Stenting of Injectable Biodegradable Elastomers for Cardiovascular Disease

A. Weaver1, K. Swett2, J. Talton2, R. Barnard2, S. Schoell1, and J. Stitzel1

J. Yang1, M. Albaghdadi2, M. Kibbe2, and G. Ameer1,2,3

Wake Forest University Center for Injury Biomechanics, Winston-Salem, NC, 2Wake Forest University School of Medicine, Winston-Salem, NC

Northwestern University, Evanston, IL, 2Northwestern University, Chicago, IL, 3Feinberg School of Medicine, Chicago, IL

5:45PM

1

1

4:45PM

Inferior Vena Cava Strut Perforation Leads to Further Strut Perforation J. Dowell1, J. Castle1, M. Schickel2, G. Guy1, X. Yang1, and S. Ghadiali1,2

Simulation of Pressure Wave Transmission in Human Ear with Viscoelastic Tympanic Membrane Model T. Hawa1 and R. Gan1 1

The University of Oklahoma, Norman, OK

Wexner Medical Center, The Ohio State University, Columbus, OH, 2The Ohio State University, Columbus, OH

1

Track: Bioinformatics, Computational and Systems Biology OP-Thurs-3-15 - Room 202A

5:00PM

Physiological Assessment and Recharging for a Fetal Pacemaker A. Vest1 and G. E. Loeb1 1

University of Southern California, Los Angeles, CA

Cell Regulatory Circuits

5:15PM

Toxin Clearance In A Compact Hemodialysis Device Enabled By Ultrathin Nanomembranes

Chairs: Amy Brock, Princess Imoukhuede

D. Johnson1 and J. McGrath1

A Spatiotemporal microRNA Circuit Controlling Cancer Stem Cell Division

1

University of Rochester, Rochester, NY

X. Shen1 and P. Bu1

5:30PM

Membrane Separation As Novel Solution For CO 2 Removal in Anesthesia Circuits F. Wilfart1, D. Roach1, J. Haelssig1, and M. Schmidt1 1

4:30PM Invited

1

Cornell University, Ithaca, NY

5:00PM

Gene Regulatory Networks in Mesendoderm Differentiation of Human Embryonic Stem Cells

Dalhousie University, Halifax, NS, Canada

R. Carpenedo1,2 and W. Stanford2,3

5:45PM

Effects of a Biventricular, Non-Blood Contacting Transmural Cardiac Assist Device on Aortic Pressure and Pulmonary Artery Pressure in an Acute Failure Model

1

E. Hord1, C. Bolch2, E. Tuzun3, and J. Criscione1

A Dynamic Regulatory Circuit in Single Breast Epithelial Cells and Basal-like Premalignancies

Texas A&M University, College Station, TX, CorInnova, Inc., College Station, TX, Texas A&M Institute for Preclinical Studies, College Station, TX

1

2

3

Ottawa Hospital Research Institute, Ottawa, ON, Canada, 2University of Ottawa, Ottawa, ON, Canada, 3Ottawa Hospital Research Institute, Ottawa, Canada

5:15PM

C-C. Wang1, S. Bajikar1, L. Jamal1,2, K. Atkins1, and K. Janes1 1

University of Virginia, Charlottesville, VA, 2UC San Diego, La Jolla, CA

BMES 2014

89

Thursday | OCTOBER 23 | 2014

Platform Sessions Thurs-3 4:30PM - 6:00PM

5:30PM

A Logic-Based Model of Cardiac Fibroblast Signaling Predicts SwitchLike Behavior A. Zeigler1, W. Richardson1, J. Holmes1, and J. Saucerman1 1

University of Virginia, Charlottesville, VA

5:45PM

Mechanistic Insights into Early Endoderm Differentiation of Human Embryonic Stem Cells using Systems Level Analysis of Signaling Interactions S. Mathew1, S. Sundararaj1, H. Mamiya1, and I. Banerjee1,2 Platform Sessions

Th-3

University of Pittsburgh, Pittsburgh, PA, 2McGowan Institute for Regenerative Medicine, Pittsburgh, PA

1

Track: Biomedical Imaging and Optics OP-Thurs-3-17 - Room 203A

Molecular Probes II Chairs: Zhiliang Cheng, Amber Doiron 4:30PM

Hyaluronic Acid Derived Nanoparticles with Activatable Fluorescence for Image-Guided Tumor Surgery A. Mohs1,2,3, T. Hill1, S. Kelkar1, F. Marini2,3, and E. Levine3 Wake Forest - Virginia Tech School of Biomedical Engineering and Sciences, WinstonSalem, NC, 2Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, Comprehensive Cancer Center of Wake Forest University, Winston-Salem, NC

1

3

Track: Orthopaedic and Rehabilitation Engineering, Tissue Engineering OP-Thurs-3-16 - Room 202B

Structure-Function Relationships in Musculoskeletal Tissues

4:45PM

Magneto-Acoustic Micro-platform for Gene Delivery and Image-Based Prediction of Therapeutic Response B. Chertok1 1

University of Michigan, Ann Arbor, MI

5:00PM

Chairs: Dawn Elliott ,Virginia Ferguson

Sortase-Tag Expressed Protein Ligation (STEPL): Combining Protein Purification and Site-Specific Bioconjugation Into a Single Step

4:30PM Invited

R. Warden-Rothman1 and A. Tsourkas1

Multiscale Mechanical Testing of Intact and Notched Tendon to Quantify Shear Load Transfer Between Collagen Fibrils S. Szczesny1 and D. Elliott2 1

University of Pennsylvania, Philadelphia, PA, University of Delaware, Newark, DE 2

4:45PM

Relating Tribological Function of Cartilage to Pproperties and Structure D. Burris1 and A. Moore1 1

University of Delaware, Newark, DE

5:00PM

Elastin Dominates Extracellular Matrix Mechanics in Ligament H. Henninger1, W. Valdez1, S. Scott1, and J. Weiss1 1

University of Utah, Salt Lake City, UT

1

University of Pennsylvania, Philadelphia, PA

5:15PM

Synthesis of Various MnF2 Nanostructures with Single-Band Red Emission Z. Bai1 and N. Hashemi1 1

Iowa State University, Ames, IA

5:30PM

Treatment of Cancer Micrometastasis Using a Chain-like Nanoparticle P. Peiris1, A. Abramowski1, R. Toy1, L. Bauer1, E. Doolittle1, W. Schiemann1, K. Ghaghada2, M. Griswold1, and E. Karathanasis1 1

Case Western Reserve University, Cleveland, OH, 2Texas Children's Hospital, Houston, TX

5:45PM

5:15PM

Gold Core Polyphosphazene Nanospheres as Biodegradable Contrast Agents for Computed Tomography

V. Ferguson1, B. Harley2, and S. Bryant1

R. Cheheltani1, P. Chhour1, M. Akhter 1, R. Ezzibdeh 1, C. Blundell 1, P. Naha 1, V. Ferrari 1, H. Allcock 2, and D. Cormode 1

Reverse Engineering of the Osteochondral Interface University of Colorado at Boulder, Boulder, CO, 2University of Illinois at Urbana-Champaign, Urbana Champaign, IL

1

University of Pennsylvania, Philadelphia, PA, 2Pennsylvania State University, University Park, PA

1

5:30PM

Elastin Deficiency Corresponds to Dose-Dependent Reduction in Tendon Mechanics M. Espinosa1, Q. Wu1, I. Stoilov1, R. Mecham1, and S. Lake1 1

Washington University in St. Louis, St. Louis, MO

5:45PM

Strain Transfer from Tissue to Cells in Meniscus is Dependent on Maturity and Microstructure W. Han1, S-J. Heo1, T. Driscoll1, L. Smith1, R. Duncan2, R. Mauck1, and D. Elliott2 1

University of Pennsylvania, Philadelphia, PA, 2University of Delaware, Newark, DE

Track: Biomechanics, Orthopaedic and Rehabilitation Engineering OP-Thurs-3-18 - Room 204A

Orthopaedic Biomechanics Chairs: Sriram Balasubramanian, Spencer Lake 4:30 PM - 4:45 PM

Statistical Shape Modeling of Cortical Bone Thickness in Patients with Femoroacetabular Impingement P. Atkins1, P. Mukherjee1, S. Singla1, S. Elhabian1, M. Harris1, J. Weiss1, R. Whitaker1, and A. Anderson1 1

University of Utah, Salt Lake City, UT

4:45PM

Nano-mechanical Variation of Orthogonal Directions in Normal and Osteoporotic Cortical Bone K. Grover1, M. Hu1, L. Lin1, and Y. Qin1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

90

BMES 2014

Stony Brook University, Stony Brook, NY

4:30PM - 6:00PM Platform Sessions Thurs-3

2014 | OCTOBER 23 | Thursday

5:00PM

Determine Proteoglycan Content of Articular Cartilage Using Indentation Test and a Nonlinear Inhomogeneous Triphasic Model X. Chen , B. Zimmerman , L. Ruggiero , and X. Lu 1

1

1

1

1

University of Delaware, Newark, DE

5:15PM

Point-of-Failure Prediction in a High-Energy Femoral Neck Fracture Model G. Feuer1, R. Pivec1, S. Hossain1, S. Saha1, and C. Paulino1 1

SUNY Downstate, Brooklyn, NY

5:30PM

Bone Fragment Motion with Lag and Locking Volar Plate Fixation of Distal Radius Fractures A. Eberhardt1, C. Wise1, T. Marshall1, J. Schwertz1, and N. Chaudhari 1 1

University of Alabama at Birmingham, Birmingham, AL

5:45PM

Biomechanical Comparison of Two Schatzker Type II Tibial Split Depression Repairs P. Brown1, M. Davis1, J. Yanik2, M. Langfitt3, S. Saunders3, E. Carroll3, and J. Stitzel1 WFU-VT School of Biomedical Engineering and Sciences, Winston Salem, NC, 2Wake Forest University School of Medicine, Winston Salem, NC, 3Wake Forest Baptist Medical Center, Winston Salem, NC 1

Track: Biomedical Engineering Education (BME) OP-Thurs-3-19 - Room 203B

Effective Use of Technology in the BME Classroom Chairs: Ann Saterbak, Damir Khismatullin The purpose of the special session is to disseminate best practices around using the wide range of available technology to support and enhance student learning for biomedical engineering education.Technology includes innovative tools for hands-on and experiential learning; mathematical modeling tools; simulation and visualization tools; personal response systems (i.e., clickers); mobile applications; videos during, before or after class, including a flipped classroom model; social media; and others. The session will include speakers, technology demonstrations, and a panel.This special session is hosted by the BMES Education Committee and will follow the Thursday afternoon BMES Education track abstract-driven platform session focusing on teaching in a flipped classroom. Speakers: Richard Hart, PhD, Chair, Department of Biomedical Engineering, The Ohio State University Cathy Wicks, Texas Instrument Naomi Chesler, PhD, University of Wisconsin-Madison Kurt Thoroughman, PhD, Associate Professor, Department of Biomedical Engineering,Washington University in St. Louis

4:00 PM – 7:30 PM Convention Center, Ballroom A

Korea-US Joint Workshop in Biomedical Engineering The goal of the Joint Workshop between the Korean Society of Medical and Biological Engineering (KOSOMBE) and BMES is to promote cooperation, collaboration and networking between the two societies and their members. 4:00-5:10PM INVITED ORALS SESSION 1 Chairs: Jungwook Shin (Inje Univ. Pusan, Gyeongsangnam-do, Korea) James Moon (Univ. Michigan, Ann Arbor, MI, USA) 4:00PM Introductory Remarks HANJOONG JO , Georgia Tech and Emory University, Atlanta, GA, USA 4:05PM Dynamic Nanocarriers for Biologic Drug Delivery PATRICK S. STAYTON, University of Washington, Seattle,WA, USA 4:20PM Tissue Regeneration and Drug Delivery using in situ forming Hydrogels KI DONG PARK , Ajou University, Suwon, Gyeonggi-do, Korea 4:35PM Big Image Data Analytics to Predict Stem Cell Fate MICHAEL CHO, University of Illinois in Chicago, Chicago, IL, USA 4:50PM Prohealing Multifunctional Endothelium Mimicking Nanomatrix HO-WOOK JUN, University of Alabama, Birmingham, AL, USA 5:00PM Nano-Engineering of 3D Complex Tissues with Controllable Architecture and Function DEOK-HO KIM, University of Washington, Seattle,WA, USA 5:10-6:00PM POSTER SESSION 6:00-7:10 INVITED ORAL SESSION 2 Chairs: Luke Lee (UC Berkeley, Berkeley, CA, USA) Minho Kim (Kent State Univ.Kent, OH) 6:00PM Microfluidic Assays for Cells, Tissues, and Artificial Organs JE-KYUN PARK KAIST, Daejeon, Chungcheongnam-do, Korea 6:15PM Microsystems for Shaping and Sensing Cell ALEXANDER REVZIN, UC Davis, Davis, CA, USA 6:30PM Activatable Nanoprobes For Molecular Imaging ICK CHAN KWON KIST, Seoul, Korea 6:45PM Synthetic Virology: Reprogramming Viruses Into Controllable Nanodevices JUNGHAE SUH, Rice University, Houston,TX, USA 7:00PM Shape Memory External Supports For Vascular Grafting HAK-JOON SUNG, Vanderbilt University, Nashville,TN, USA 7:10-7:30PM Closing Remarks & Announcements KWIWON CHOI , KIST, Seoul, Korea

BMES 2014

91

Platform Sessions

Th-3

137 236 237 336 337 436 437 536 537 636

THURSDAY REFRESHMENT BREAKS

200 199 181 182

220 219 201 202

240 239 221 222

280 279 261 262

300 259 281 282

178 163

198 183

218 203

238 223

258 243

278 263

298 283

137 136 124 125

157 156 144 145

177 176 164 165

197 196 184 185

217 216 204 205

237 236 224 225

257 256 244 245

276 265

297 296 284 285

94 87

115 114 106 107

135 134 126 127

155 154 146 147

175 174 166 167

195 194 186 187

215 214 206 207

235 234 226 227

255 254 46 247

275 274 266 267

295 294 286 287

73 68

93 88

113 108

133 128

153 148

173 168

193 188

213 208

233 228

253 248

273 268

293 288

52 49

72 69

92 89

31 30

51 50

71 70

91 90

112 111 109 110

132 131 129 130

152 151 149 150

172 171 169 170

192 191 189 190

212 211 209 210

232 231 229 230

252 251 249 250

272 271 269 270

292 291 289 290

312 311 301 302

324 323 313 314

336 335 325 326

348 347 337 338

360 359 349 350

372 371 361 362

384 383 373 374

396 395 385 386

408 407 397 398

420 419 409 410

432 431 421 422

444 443 433 434

456 455 445 446

468 467 457 458

480 479 469 470

310 303

322 315

334 327

346 339

358 351

370 363

382 375

394 387

406 399

418 411

430 423

442 435

454 447

466 459

478 471

309 308 304 305

321 320 316 317

333 332 328 329

345 344 340 341

357 356 352 353

369 368 364 365

381 380 376 377

393 392 388 389

405 404 400 401

417 416 412 413

429 428 424 425

441 440 436 437

453 452 448 449

465 464 460 461

477 476 472 473

307 306

319 318

331 330

343 342

355 354

367 366

379 378

391 390

403 402

415 414

427 426

439 438

451 450

463 462

475 474

514 513 501 502

528 527 515 516

542 541 529 530

552 551 543 544

566 565 553 554

580 579 567 568

594 593 581 582

608 607 595 596

622 621 609 610

636 635 623 624

650 649 637 638

664 663 651 652

678 677 665 66

688 687 679 680

702 701 689 690

512 503

526 517

540 531

550 545

564 555

578 569

592 583

606 597

620 611

635 625

648 639

662 653

676 66

686 681

700 691

511 510 504 505

525 524 518 519

539 538 532 533

549 548 546 547

563 562 556 557

577 576 570 571

591 590 584 585

605 604 598 599

619 618 612 613

633 635 626 627

647 646 640 641

661 660 654 655

675 674 668 669

685 684 682 683

699 698 692 693

509 508 506 507

523 522 520 521

537 536 534 535

561 560 558 559

575 574 572 573

589 588 586 587

603 602 600 601

617 616 614 615

631 630 628 629

645 644 642 643

659 685 656 657

673 672 670 671

REFRESHMENT BREAKS

180 179 161 162 158 143

117 116 104 105

95 86

74 67

53 48

32 29

11 10

REFRESHMENT BREAKS

160 159 141 142 138 123

96 85

75 66

54 47

33 28

12 9

BIOINFORMATICS

140 139 121 122 118 103 97 84

76 65

55 46

34 27

13 8

260 259 241 242

AND

BIO MECHANICS

MUSCULOSKELETAL INJURY AND

MECHANICS

TISSUE ENGINEERING

REGENERATION AND REHAB

DEVICES AND

SENSORS

AND

MOLECULAR

FUNCTION

TISSUE EN’G

DRUG

DELIVERY

CANCER

697 696 694 695

120 119 101 102 98 83

56 45

35 26

14 7

BME

99 82 78 63

57 44

36 25

15 6

CELLULAR

100 81 79 62

58 43

37 24

16 5

MULTI SCALE MODELS

80 61 59 42

38 23

17 4

MATERIALS

AND

APPROACHES

TECHNOLOGIES,

EMERGING

IMAGING

EDUCATION

60 41

39 22

18 3

P O S T E R S

40 21

19 2

P O S T E R S

20 1

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

2014 | october 23 | Thursday

- 10:30am, 3:30pm - 4:30pm P-Th-282 The Use of Kernel PCA For The Channelization Of The Hotelling Model Observer

THURSDAY, October 23, 2014 9:30 AM - 5:00 PM POSTER SESSIONS – Thurs

G. Wen1,2 and M. Markey1,2 The University of Texas at Austin, Austin, TX, 2The University of Texas MD Anderson Cancer Center, Houston, TX

1

P-Th-283 Nonlinear Model Development and Optimization of Glucose Affinity Sensors

Device and Sensors: P-Th-1 to P-Th-124 Tissue Engineering: Regeneration and Rehabilitation: P-Th-125 to P-Th-167

L. Reis1 and E. Guilbeau1 1

Louisiana Tech University, Ruston, LA

P-Th-284 Computational Saliency Maps of Medical Images to Predict Radiologists' Gaze Fixations

Musculoskeletal Injury and Mechanics: P-Th-168 to P-Th-231

F. Pecen1, G. Wen1,2, T. Ganapathi1, D. Vining2, T. Haygood2, and M. Markey1,2

Multiscale Models and Biomechanics: P-Th-232 to P-Th-269

P-Th-285 A Neural Network based Human Platelet Calcium Calculator trained by Pairwise Agonist Scanning

Bioinformatics: P-Th-270 to P-Th-296 and P-Th-476 to P-Th-480 Cancer: P-Th-301 to P-Th-334

University of Texas at Austin, Austin, TX, 2University of Texas MD Anderson Cancer Center, Houston, TX

1

M. Lee1 and S. Diamond1 1

University of Pennsylvania, Philadelphia, PA

P-Th-286 Identifying MRI Markers On Newly Diagnosed Glioblastoma Multiforme To Distinguish Patients With Long And Short Term Survival J. Patel1, P. Prasanna1, P. Tiwari1, and A. Madabhushi1 1

Drug Delivery: P-Th-335 to P-Th-388

Case Western Reserve University, Cleveland, OH

Track: Bioinformatics, Computational and Systems Biology

Tissue Engineering: P-Th-391 to P-Th-407

Dynamics of Biological Systems

Cellular and Molecular Function: P-Th-409 to P-Th-470

P-Th-287 Belief Propagation in Genotype-Phenotype Networks

Chairs: Chun-Chao Wang, Janet Barzilla

Emerging Technologies, Approaches and Materials: P-Th-501 to P-Th-620 Imaging: P-Th-621 to P-Th-662

J. Moharil1, P. May1, D. Gaile1, and R. Hageman Blair1 1

State University of New York-University at Buffalo, Buffalo, NY

P-Th-288 Characterizing Collagen Network Mechanics And Cell-Mediated Remodeling Using An Agent-Based Model J. Reinhardt1 and K. Gooch1 1

The Ohio State University, Columbus, OH

P-Th-289 Spatial Organization in Molecularly-Tethered Lipid Bilayers

BME Education: P-Th-663 to P-Th-692

S. Abel1 1

Track: Bioinformatics, Computational and Systems Biology

Algorithms for Computational and Systems Biology Chairs: Michael Fenn, Kristen Naegle P-Th-281 RVD2: A Variant Detection Model For Heterogeneous Next-generation Sequencing Data

University of Tennessee, Knoxville, TN

P-Th-290 Key Features of the Gut Microbiome Revealed by Topological and Dynamic Network Analysis M. Biggs1, S. Steinway2, J. Papin1, and R. Albert3 1 University of Virginia, Charlottesville, VA, 2Pennsylvania State College of Medicine, Hershey, PA, 3Pennsylvania State University, University Park, PA

P-Th-291 A Model for Metabolism in Ischemic Cardiomyocytes A. McDougal1, D. Sosnovik2, and C. Dewey1 Massachusetts Institute of Technology, Cambridge, MA, 2Massachusetts General Hospital, Boston, MA

1

Y. He1 and P. Flaherty1 1

Worcester Polytechnic Institute, Worcester, MA

See page 92 for Poster floor plan

BMES 2014

93

Poster Session

Th

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-292 Mechanistic Characterization of the Thioredoxin System in the Removal of Hydrogen Peroxide

P-Th-275 Development of a Simplified and Computationally Efficient Human Body Finite Element Model

V. Pannala1 and R. Dash1

D. Schwartz1,2, D. Moreno1,2, J. Stitzel1,2, and S. Gayzik1,2

1

Medical College of Wisconsin, Milwaukee, WI

P-Th-293 Cathepsin Cannibalism Reduces Collagen And Elastin Degradation In Matrix Remodeling M. Ferrall1 and M. Platt1 1

Wake Forest School of Medicine, Winston Salem, NC, 2Virginia Tech – Wake Forest University Center for Injury Biomechanics, Winston Salem, NC

1

Georgia Institute of Technology and Emory University, Atlanta, GA

P-Th-276 An In Silico Multi-Compartment Model of VEGF165 and VEGF165b in Peripheral Arterial Disease G. Chen1, L-H. Chu1, B. Annex2, and A. Popel1 1

P-Th-294 Nucleotide and Phosphate Regulation of Mitochondrial Oxidative Phosphorylation J. Bazil1, F. Van den Bergh1, D. Beard1, R. Wiseman2, and K. Vinnakota1 Poster Session

Th

1

University of Michigan, Ann Arbor, MI, 2Michigan State University, East Lansing, MI

P-Th-277 Characterization and Comparative Analysis of the Kinetics of Cardiac Cytosolic and Mitochondrial Malate Dehydrogenase Isoforms S. Dasika1, K. Vinnakota1, and D. Beard1 1

P-Th-295 Strategic Priming with Several Antigens Yields Multiple Memory Paradigms C. Ziraldo1, C. Gong1, D. Kirschner1, and J. Linderman1 1

University of Michigan, Ann Arbor, MI

P-Th-296 Comparison of New Agent-Based Model to a Classical Discrete Model of Angiogenesis M. Kelly-Goss1, B. Corliss1, C. Pelland1, and S. Peirce-Cottler1 University of Virginia, Charlottesville, VA

1

S. Miller1 and K. Mitra1 1

S. Hunt1, Y. Segal1, K. Dorfman1, and V. Barocas1

S. Smith1, S. Ravindranathan1, K. Nguyen1, and D. Zaharoff1 1

University of Arkansas, Fayetteville, AR

P-Th-271 The Influence of Glycosaminoglycan Distribution in Collagen on Its Mechanical Property Y. Bi1, P. Patra1, and X. Xiong1 1

N. Drew1, D. Baldo 1, and A. Grosberg1 University of California, Irvine, Irvine, CA

Track: Bioinformatics, Computational and Systems Biology

Signaling Systems Analysis Chairs: Kathryn Miller-Jensen, Jeff Saucerman P-Th-476 Regulation of Store-Operated Calcium Entry in Endothelial Flow-Induced Nitric Oxide Production T. Muzorewa1, D. Jaron1, D. Buerk1, and K. Barbee1

University of Bridgeport, Bridgeport, CT

1

P-Th-272 Mathematical Modeling and Experimental Validation of Cancer Cell Migration in a Three-Dimensional Tumor Matrix S. Boukhris1 and Y. Feng1 1

University of Minnesota, Minneapolis, MN

P-Th-280 Evaluating the Consistency of Cardiomyocyte Self-assembly

Multiscale Modeling P-Th-270 Mathematical Model of Protein Delivery Within the Urinary Bladder

Florida Institute of Technology, Melbourne, FL

P-Th-279 Influence of Transport in the Glomerular Mesangium

1

Chairs: Shayn Peirce, Ashlee Ford Versypt

University of Michigan, Ann Arbor, MI

P-Th-278 Simulation of Dependence of Radiative Energy Transport on Tissue Optical Properties

1

Track: Bioinformatics, Computational and Systems Biology

Johns Hopkins University, Baltimore, MD, 2University of Virginia, Charlottesville, VA

The University of Texas at San Antonio, San Antonio, TX

P-Th-273 Mixture Theory Data Reduction for Cerebral Blood Flow Predictions I. Gould1 and A. Linninger1

Drexel University, Philadelphia, PA

P-Th-477 Feedback From IGFBP2 to HIF1α Determines Glioblastoma Progression K. Lin1, A. Liao1, and A. Qutub1 1

Rice University, Houston, TX

P-Th-478 Intracellular T Cell Signaling: Experimental And Computational Tools For A Frequency Response Analysis Approach A. Kniss1, L. Chingozha2, H. Lu1,2, and M. Kemp1

University of Illinois at Chicago, Chicago, IL

1

Georgia Institute of Technology and Emory University, Atlanta, GA, 2Georgia Institute of Technology, Atlanta, GA

1

P-Th-274 A Multiscale Adhesive Dynamics Model to Study the Interaction of Neutrophils with the Endothelium A. Rocheleau , R. Sumagin , and M. King 1

1

2

1

Cornell University, Ithaca, NY, 2Emory University, Atlanta, GA

P-Th-479 Spatial Differentiation Patterns Evaluated Via Rules Governing Intercellular Communication C. Glen1,2, T. C. McDevitt1,2, and M. L. Kemp1,2 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

94

BMES 2014

Georgia Institute of Technology, Atlanta, GA, 2Emory University, Atlanta, GA

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

P-Th-480 Quantitative Modeling of the Alternative Pathway of the Complement System Activation D. Morikis1, R. Gorham1, and N. Zewde1 1

University of California, Riversdie, Riverside, CA

Track: Bioinformatics, Computational and Systems Biology, New Frontiers and Special Topics

Systems Approaches to Therapy and Therapeutics Chairs: Cheemeng Tan, Mohammad Fallahi-Sichani

)

R. Gorham Jr.1 and D. Morikis1 1

University of California, Riverside, Riverside, CA

E. Pienaar1, N. Cilfone1, P. Lin2, V. Dartois3, J. Mattila4, R. Butler5, J. Flynn4, D. Kirschner1, and J. Linderman1 University of Michigan, Ann Arbor, MI, 2University of Pittsburgh Medical Center, Pittsburgh, PA, 3The State University of New Jersey, Neward, NJ, 4University of Pittsburgh, Pittsburgh, PA, 5Adventist University of Health Sciences, Orlando, FL

1

P-Th-571 PADPIN: Protein-Protein Interaction Networks of Angiogenesis, Arteriogenesis, and Inflammation in Peripheral Arterial Disease L-H. Chu1, B. Annex2, J. Bader1, and A. Popel1 1Johns Hopkins University, Baltimore, MD, 2University of Virginia, Charlottesville,VA P-Th-572 Psychometric Analysis of Alzheimer's Disease Assessment Scale N.Verma1,2 and M. Markey1,3 1The University of Texas at Austin, Austin, TX, 2NeuroTexas Institute, St. David's HealthCare, Austin, TX, 3The University of Texas MD Anderson Cancer Center, Houston, TX P-Th-573 A Mechanistic Model of Chimeric Antigen Receptor (CAR) T Cell Activation J. Rohrs , P. Wang , and S. Finley 1

1

1

University of Southern California, Los Angeles, CA

P-Th-574 Quantitative Analysis of Hemodynamics in a Novel Standardized Geometry Reveals Inconsistencies between Newtonian and Non-Newtonian Constitutive Models J. Weddell1, J. Kwack1, A. Masud1, and P. Imoukhuede1 1

University of Illinois at Urbana-Champaign, Urbana, IL

P-Th-575 Cytoskeletal Fingerprinting of Human Stem Cell Populations to Reduce Heterogeneity A. Paul , K. Danielson , and M. Cho 1

1

1

1

University of Illinois at Chicago, Chicago, IL

Track: Bioinformatics, Computational and Systems Biology, Cellular and Molecular Bioengineering

Understanding Molecular Functions from Systems and Computational Approaches Chairs: Kevin Janes, Jason Papin P-Th-409 Integrated Network Analysis of CD133+ Colon Cancer Stem Cell K-Y. Chen1, X. Liu1, P. Bu1, C-S. Lin1, N. Rakhilin1, J. Locasale1, and X. Shen1 Cornell University, Ithaca, NY

P-Th-410 Principal Component Analysis of the Regulation of Osteoclastogenesis by Salubrinal and Guanabenz A. Chen1, K. Hamamura2, N. Tanjung2, and H. Yokota2

P-Th-570 High Bacterial Burden And Sub-optimal Antibiotic Concentrations Result In Failed TB Treatment

1

- 10:30am, 3:30pm - 4:30pm

1

P-Th-569 In silico Development of Complement System Biomarkers

2014 | october 23 | Thursday

Purdue University, West Lafayette, IN, 2Indiana University Purdue University Indianapolis, Indianapolis, IN

1

P-Th-411 Mechanistic Insights into Major Human Muscular Diseases S. Gupta1, S-M. Kim1, Y. Wang1, A. Dinasarapu2, and S. Subramaniam1 1

University of California, San Diego, La Jolla, CA, 2University of Florida, Gainesville, FL

P-Th-412 Meta-analysis for Identifying Gene Expression Patterns in Head and Neck Cancer C. Kaddi1, S. Mishra1, and M. Wang1 1

Georgia Institute of Technology, Atlanta, GA

P-Th-413 System Characterization of microRNAs in the Mouse Model of Peripheral Arterial Disease C. Chen1, L-H. Chu1, B. Annex2, and A. Popel1 1

Johns Hopkins University, Baltimore, MD, 2University of Virginia, Charlottesville, VA

P-Th-414 Reverse Engineering of Genome-Scale Biological Networks in MCF-7 Breast Cancer Cell Line R. Thiagarajan1, D. Wu2, J. Bazil1, S. Kron2, and D. Beard1 University of Michigan Medical School, Ann Arbor, MI, 2The University of Chicago, Chicago, Illinois, Chicago, IL

1

)

P-Th-415 Identification and Characterization of the Monoclonal Antibodies Comprising the Serological Response to Seasonal Influenza Vaccines J. Lee1, D. Boutz1, C. Vollmers2, B. DeKosky1, A. Horton1, G. Ippolito1, E. Marcotte1, S. Quake2, and G. Georgiou1 1

University of Texas at Austin, Austin, TX, 2Stanford University, Stanford, CA

P-Th-416 Genital Tract Inflammation Perturbs Mucosal Integrity Proteins: Implications for HIV Susceptibility K. Arnold1, A. Burgener2,3, K. Bersie2, L. Dunphy1, K. Shahabi4, J. Kwatampora5, J. Kimani2,5, R. Kaul4, D. Lauffenburger1, and L. McKinnon6 Massachusetts Institute of Technology, Cambridge, MA, 2University of Manitoba, Winnipeg, MB, Canada, 3National Microbiology Lab, Winnipeg, MB, Canada, 4University of Toronto, Toronto, ON, Canada, 5University of Nairobi, Nairobi, Kenya, 6Centre for the AIDS Programme of Research in South Africa, Durban, South Africa

1

P-Th-417 Linking Magnetic Relaxation to Protein Folding P. Liu1, R. Kulwin1, and R. Lee1 1

University of Chicago, Chicago, IL

See page 92 for Poster floor plan

BMES 2014

95

Poster Session

Th

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm

Track: Biomaterials

P-Th-593 Microfabricated Nanoporous Gold Coatings Promote Cortical Cell TypeDependent Surface Attachment

Intelligent/Multifunctional Biomaterials

C. Chapman1, H. Chen1, M. Stamou1, M. Biener2, P. Lein1, and E. Seker1

Chairs: Meng Deng, Wei Li

)

P-Th-585 Characterization of a Multi-functional Hydrogel Tissue Adhesive Containing Chitosan L. Sanders1, K. Webb1, T. Mefford1, and J. Nagatomi1 1

Clemson University, Clemson, SC

P-Th-586 Collecting of Circulating Tumor Cells with Biocompatible/thermoresponsive PMEA analogous surfaces Poster Session

Th

T. Orui1, K. Sato1, T. Hoshiba1, and M. Tanaka1 1

Yamagata University, Yonezawa, Japan

O. Tokareva1,2, D. Glettig1, R. Abbott1, and D. Kaplan1 Tufts Unoversity, Medford, MA, 2Massachusetts Institute of Technology, Cambridge, MA

P-Th-588 Shape-Controlled Synthesis of Degradable Polymeric Microfibers Z. Bai1, F. Sharifi1, and N. Hashemi1 1

Iowa State University, Ames, IA

P-Th-589 Characterization Of Poly-Dimethylsiloxane As a Non-hermetic Micropackaging Material For Chronic Implantable Microsystems D. Sun1, L. Shem1, P. Wang1, C. Zorman1, P. Feng1, and W. Ko1 1

1 Brown University, Providence, RI, 2Columbia University, New York, NY, 3Stanford University, Stanford, CA, 4NASA Ames Research Center, Mountain View, CA

P-Th-595 Bio-inspired Hybrid Nanosack for Pancreatic Islet Transplantation in the Omentum University of Alabama at Birmingham, Birmingham, AL

1

P-Th-596 Antibacterial Effect and Osteogenetic Properties of TiO2 nanotubes Incorporated with ZnO W. LIU1,2, P. SU3, S. CHEN4, Z. ZHANG4, H. LIU3, and T. WEBSTER1 Northeastern University, BosTON, MA, 2Capital Medical University, Beijing, China, People's Republic of, 3Beijing University of Technology, BEIJING, China, People's Republic of, 4Capital Medical University, BEIJING, China, People's Republic of

1

P-Th-597 Impact of Hirschsprung's Disease on the Barrier Properties of Colonic Mucus T. Carlson1, H. Yildiz1, A. Goldstein2, and R. Carrier1 Northeastern University, Boston, MA, 2Massachusetts General Hospital, Boston, MA

A. Means1, R. Fei1, J. George1, J. Park1, A. Abraham1, G. Cote1, and M. Grunlan1

P-Th-598 Nanoparticle-Protein Separations with Nanoporous Silicon Nitride Membranes J. Winans1, J-P. DesOrmeaux2, S. Wayson1, T. Gaborski3, T. Khire1, C. Striemer2, and J. McGrath1 1 University of Rochester, Rochester, NY, 2SiMPore, West Henrietta, NY, 3Rochester Institute of Technology, Rochester, NY

Texas A&M University, College Station, TX

P-Th-591 Click-Chemistry Based Molecularly Responsive Hydrogel as Biodegradable Scaffolds for 3D Cell Culture R. Navarro1, K. Beaven1, J. McKenzie1, R. Hall1, K. Knutson1, and T. Betancourt1 1

E. Toomey1, S. Vecchioni2, M. Capece3, N. Le1, A. Ray3, A. Greenberg3, G. Wessel1, and L. Rothschild4

1

Case Western Reserve University, Cleveland, OH

P-Th-590 Self-Cleaning, Mechanically Robust Membranes for Implanted Glucose Biosensors 1

P-Th-594 Biological Nanowires: Silver-mediated Base Pairing for Conductivityenhanced DNA/ single Ion Intercalation Chains in (microbial) DNA

P. Hwang 1, D-J. Lim1, A. Tambralli1, S. Gilbert1, L. Tian1, A. Shalev1, and H-W. Jun1

P-Th-587 Recombinant Spider Silks for Delivery of Therapeutic Nucleic Acids 1

University of California, Davis, Davis, CA, 2Lawrence Livermore National Laboratory, Livermore, CA

1

Texas State University, San Marcos, TX

P-Th-599 Overcoming CARPA while Stopping Internal Bleeding with Hemostatic Nanoparticles D. Hickman1, A. Shoffstall1, R. Groynom1, E. Shoffstall1, and E. Lavik1 Case Western Reserve University, Cleveland, OH

1

P-Th-600 Towards Safer Nanomaterials: Investigating Endothelial Cell Mechanical Properties and Barrier Function

Track: Biomaterials, Nano to Micro Technologies

Micro and Nanostructured Materials Chairs: Meng Deng, Wei Li P-Th-592 Dependence of Nanostructures on Surface Energy for the Enhanced Differentiation and Maturation of Osteoblastic Lineage Cells on Microrough Titanium Surfaces

Y. Liu1 Binghamton University, Binghamton, NY

1

P-Th-601 Metal Binding Properties of Adeno-associated Virus with Hexahistadine Capsid Functionalization J. Zhao1, C. Dempsey1, A. Nixon1, and J. Suh1 Rice University, Houston, TX

1

E. Lotz , R. Olivares-Navarrete , S. Hyzy , S. Berner , Z. Schwartz , , and B. Boyan1,4

P-Th-602 Three-dimensional All-carbon Scaffolds for Stem Cell Maintenance

Virginia Commonwealth University, Richmond, VA, 2Institut Straumann AG, Basel, Switzerland, 3University of Texas Health Science Center at San Antonio, San Antonio, TX, Georgia Institute of Technology, Atlanta, GA

G. Lalwani1, A. Gopalan1, M. D'Agati1, M. Rao1, J. Schneller1, and B. Sitharaman1

1

1

4

1

1

2

1 3

Stony Brook University, Stony Brook, NY

1

P-Th-603 Selenium Nanoparticle Coatings for Alteration in Cancer Cell Activity M. Stolzoff1 and T. Webster1 Northeastern University, Boston, MA

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

96

BMES 2014

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

P-Th-604 Fabrication of Novel In Situ Crosslinked Carbon Nanomaterial Thin Films for Biomedical Applications S. Patel1, G. Lalwani1, and B. Sitharaman1 1

N. Schaub1, E. Franze1, and R. Gilbert1

Houston Methodist Research Institute, Houston, TX, 2Politecnico di Torino, Torino, Italy, Purdue University, West Lafayette, NJ, 4University of Houston, Houston, TX

P-Th-583 Effect of Magnesium and Other Alloying Elements on Endothelial Cells 1

L. Lee1, C. Nguyen1, A. Sharma1, B. Taussig1, S. Rao1, V. Lin1, and J-C. Chiao1 UT Arlington, Arlington, TX

P-Th-607 Mechanically Stable And Smart Titania Nanotubes On Ti-V Bone Implant Alloys S. Patel1 and T. Shokuhfar1,2 1

A. Cervadoro1,2, M. Cho1, J. Key1, C. Cooper3, C. Stigliano1, S. Aryal1, A. Brazdeikis4, J. Leary3, and P. Decuzzi1

N. Zhao1, J. Ma1, and D. Zhu1

Rensselaer Polytechnic Institute, Troy, NY

P-Th-606 Facile Fabrication and Hydrophilic/hydrophobic Patterning of an Electrospun poly(methyl methacrylate) Cellular Filter 1

P-Th-582 Iron Oxide Nanoflakes for Hyperthermia and Magnetic Resonance Imaging

3

P-Th-605 Considerations for Solvent Retention in Electrospun Fibers 1

- 10:30am, 3:30pm - 4:30pm

1

Stony Brook University, Stony Brook, NY

2014 | october 23 | Thursday

Michigan Technological University, Houghton, MI, 2University of Illinois at Chicago, Chicago, IL

North Carolina A&T State University, Greensboro, NC

P-Th-584 Influence of Ionizing Radiation on Medical Device Materials S. Cooke1, D. Meleason2, S. Mange2, S. Myers2, and A. Whittington1 Virginia Polytechnic Institute and State University, Blacksburg, VA, 2Lewis Gale Medical Center, Salem, VA

1

Poster Session

Th

Track: Biomaterials

Biomaterials – Other Chairs: Vassilios Sikacitsas, Daniel Alge

Track: Biomaterials, Translational Biomedical Engineering

Therapeutic and Theranostic Bomaterials

T. Hoshiba1, K. Sato1, and M. Tanaka1 1

Chairs: Hitesh Handa, Michael Fenn P-Th-576 An Amnion-based Barrier Membrane For Guided Bone Regeneration In Dental Implant Application W. Li1, B. Wang2, G. Ma1, B. Brazile3, and J. Liao3 Dalian Medical University, Liaoning, China, People's Republic of, 2Northwestern University, Chicago, IL, 3Mississippi State University, Mississippi State, MS

1

P-Th-577 Improved Serum Stability of Collagen Mimetic Peptides Through Structure Modification D. Smith1, L. Bennink1, and S. Yu1 1

University of Utah, Salt Lake City, UT

P-Th-578 Bioabsorabable Bone Plates Enabled with Local, Sustained Delivery of Alendronate M. Park1, W. Hur2, M. Kim1, S. Choi1, S. Lee1, C. Park1, H. Min1, T. Choi1, and Y. Choy1 Seoul National University, Seoul, Korea, Republic of, 2Seoul National University Hospital, Seoul, Korea, Republic of

1

P-Th-579 Hematological Effects of Graphene Nanoribbons

P-Th-580 Transepithelial Transport of PAMAM Dendrimers Across Isolated Intestinal Tissue D. Hubbard , H. Ghandehari , and D. Brayden 1

1

P-Th-609 Development of an In Vitro Model for Single Species and Mixed FungalBacterial Biofilms on Titanium Dental Implants D. Montelongo1, A. Srinivasan 1, A. Ramasubramanian1, and J. Lopez-Ribot1 1

The University of Texas at San Antonio, San Antonio, TX

P-Th-610 Improving Properties of In Situ Forming PLGA Implants via Poly(β-amino ester) and Hydroxyapatite Additives P. Fisher1, T. Milbrandt1, Z. Hilt1, and D. Puleo1 1

University of Kentucky, Lexington, KY

P-Th-611 Evaluation and Control of Alginate Microbead Stability for Islet Encapsulation V. Ibarra1, A. Appel1, S. Somo1, M-H. Cheng2, S-W. Kao2, M. Anastasio3, A. Garson3, E. Opara4, and E. Brey1 Illinois Institute of Technology, Chicago, IL, 2Chang Gung Memorial Hospital, Linkou, Taiwan, 3Washington University, St.Louis, MO, 4Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC 1

P-Th-612 Maintenance of Liver Function via Hepatocyte Morphology Regulation on Blood-compatible Polymers 1

SUNY Stony Brook University, Stony Brook, NY

1

Yamagata University, Yonezawa, Japan

T. Otaki1, T. Hoshiba1, and M. Tanaka1

J. Fang1, S. Chowdhury1, and B. Sitharaman1 1

)

P-Th-608 Cell Selection through the Attachment on PMEA Analogs with Different Intermediate Water Contents

2

University of Utah, Salt Lake City, UT, 2University College Dublin, Dublin, Ireland

P-Th-581 Passivation of pNIPAM Nanogels through Surface Hydrolysis Mediated PEGylation

Yamagata University, Yonezawa, Japan

P-Th-613 Increased Cellular Neurogenesis on Graphene Substrate J. Lee1, A. Lipatov1, L. Ha1, A. Sinitskii1, and J. Lim1 1

University of Nebraska-Lincoln, Lincoln, NE

P-Th-614 Adhesion and Proliferation of Stem Cells on Polymers with Different Intermediate Water Contents E. Nemoto1, T. Hoshiba1, K. Sato1, and M. Tanaka1 1

Yamagata University, Yonezawa, Japan

A. Blanchard1, J. Peters2, S. Verghese2, and N. Peppas2 1

University of Texas at Austin, Rockwall, TX, 2University of Texas at Austin, Austin, TX

See page 92 for Poster floor plan

BMES 2014

97

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-615 Enhancement of Citrate-Based Biodegradable Elastomer through the Application of Click Chemistry

P-Th-198 Biomechanical Evaluation of Knee Movements During Skilled and Unskilled Golf Swing

B. Jahanshahi1, J. Guo1, and J. Yang1

A. Choi1, H. Kim1, and J. Mun2

1

Pennsylvania State University, state college, PA

P-Th-616 LKB1 and MO25 Demonstrate Significant Interaction with Myofilament Protein M. Lopez-Pier1, J. Konhilas1, and S. Behunin1 1

The University of Texas Health Science Center at Houston, Houston, TX, 2Sungkyunkwan University, Suwon, Korea, Republic of

1

P-Th-199 Subject Ability To Accurately Characterize G's In Relation To Activities Of Daily Living W. Lee1, S. Perumal1, B. Patel1, and K. Konnaiyan1

University of Arizona, Tucson, AZ

1

Track: Biomechanics, Orthopaedic and Rehabilitation Engineering Poster Session

Th

University of South Florida, Tampa, FL

P-Th-200 Quantitative Analysis of Dummy Headform Shape for Impact Testing with Football Helmets

Clinical, Rehabilitation and Sports Biomechanics Chairs: Katherine Steele, Noah Rosenblatt

B. Cobb1, A. MacAlister1, T. Young1, A. Kemper1, S. Rowson1, and S. Duma1 1

Virginia Tech-Wake Forest University, Blacksburg, VA

P-Th-201 Regulation of Horizontal Reaction Forces Across Clubs During the Golf Swing

P-Th-190 Study of the Urethral Support Function in Women with a Computational Modeling Approach

T. Peterson1, P. Requejo1,2, H. Flashner1, and J. McNitt-Gray1

Y. Peng1 and Y. Zhang1

P-Th-202 Stress And Strain Analysis on L4-L5 Lumbar Spine While Performing Sit-Ups.

1

University of Houston, Houston, TX

University of Southern California, Los Angeles, CA, 2Rancho Los Amigos National Rehabilitation Center, Downey, CA

1

P-Th-191 Gait Analysis For Early Fall Prediction

A. Syed1, R. Mohammed1, B. Mohammed1, W. Mohammed1, and Y. Al-Smadi1

L. Petku , A. Alsamarae , and M. Nasir

P-Th-203 Pneumatic Muscle Actuator Use in Leg Extension Exercise

1

1

1

1

1

Lawrence Technological University, Southfield, MI

Texas A&M University-Kingsville, Kingsville, TX

P-Th-192 Fragile X-Associated Tremor/Ataxia Syndrome - A Case Study

E. Diller1, B. Rinehart1, J. Allen1, T. Merrell1, D. Reynolds1, and C. Phillips1

J. Lee , R. Imamura , N. Merrier , and S. Shimada

P-Th-204 Hip Biomechanics of Ballet Dancers in Closing First, Third and Fifth Position

1

1

1

2

2

CSU Sacramento, Sacramento, CA, 2Biomechanical Consultants of CA, Davis, CA

1

Wright State University, Dayton, OH

P-Th-193 Sensitivity of Lumbopelvic Rhythm to Risk Factors of Low Back Pain

A. Lopez1, S. Carey1, and M. Morris1

M. Vazirian , A. Agarwal , B. Koch , R. Tromp , and B. Bazrgari

P-Th-205 Hockey Skating Kinematics and the Effect of Skate Design

1

1

1

1

1

1

University of Kentucky, Lexington, KY

1

University of South Florida, Tampa, FL

P-Th-194 Gender Differences In How Older Adults Regulate Angular Momentum During Stair Descent

R. Tidman1, L. Lambert2, D. Cruikshank2,3, and B. Silver-Thorn1

K. Singhal1, J. Kim2, J. Casebolt2, S. Lee2, K-H. Han2, and Y-H. Kwon2

P-Th-206 Human Motion Analysis While Climbing Cliff

University of North Texas Health Science Center, Fort Worth, TX, 2Texas Woman's University, Denton, TX

1

P-Th-195 Effect of Sagittal Imbalance and Compensatory Mechanisms on Postural Stability in Spinal Deformity Patients M. Paliwal1, N. Grosland1, and S. Mendoza1 1

University of Iowa, Iowa City, IA

)

P-Th-196 Effects of Visual Feedback Distortion on Gait Speed S-J. Kim1, M. Ogilvie1, N. Shimabukuro1, and T. Stewart1 1

California Baptist University, Riverside, CA

P-Th-197 Lateral Trunk Position Can Increase Risk of Elbow Injury in Collegiate Baseball Pitchers M. Solomito1, E. Garibay1, J. Woods1, S. Ounpuu1, and C. Nissen1 1

Connecticut Children's Medical Center, Farmington, CT

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

98

BMES 2014

Marquette University, Milwaukee, WI, 2DC Hybrid Skating, Milwaukee, WI, 3Easton Hockey, Van Nuys, CA

1

S. Julakanti1, A. Mohammed1, S. Mohammed1, and Y. M Al-Smadi1 Texas A&M University, Kingsville, TX

1

P-Th-207 Inverse Dynamic and Kinetic Analysis of Seated Leg Curl Exercise V. Nekkanti1, P. Murugesu1, R. Mamidi1, R. Tondapu1, D. Patel1, and Y. M. AlSmadi1 Texas A&M University Kingsville, Kingsville, TX

1

P-Th-208 Dynamic and Kinetic Analysis of a Human Body During Push-Ups D. Joy1, R. Patel1, H. Shekhawat1, B. Ayodele1, P. Murugesu1, D. Patel1, and Y. M. Al-Smadi1 Texas A&M University Kingsville, Kingsville, TX

1

P-Th-209 Musculoskelatal Simulation of Archery A. Reddy1, N. KilaniI1, A. Shah1, and Y. M. Al-Smadi1 Texas A&M University- Kingsville, Kingsville, TX

1

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

2014 | october 23 | Thursday

- 10:30am, 3:30pm - 4:30pm

P-Th-210 Age-Related Lower-Extremity Muscle Fatigue During A Moderate-Intensity Cycling Exercise

P-Th-221 A Computational Model of the Porcine Eye

K. Stratton1, K. Momeni1, and P. Faghri1

1

1

R. Watson1,2, W. Gray1, R. Glickman1,3, B. Lund4, W. Sponsel1,5, and M. Reilly1 UTSA, San Antonio, TX, 2BRC, San Antonio, TX, 3UTHSCSA, San Antonio, TX, 4USAISR, San Antonio, TX, 5UIW, San Antonio, TX

University of Connecticut, Storrs, CT

P-Th-222 Lateral Impact and Injury Tolerance of the Lumbar Spine

P-Th-211 Comparison of Neuromuscular Activity during the Lateral Step Task in Younger and Older Adults

N. Merrier1 and S. Shimada1 1

T. Bejarano1, A. Thota1, D. Brunt1, and R. Jung1 1

Florida International University, Miami, FL

P-Th-223 Probability of Fall Due To Trip Hazard Via Computer Simulations H. Chittam1, K. Das1, B. Pavan1, and W. Lee1

Track: Biomechanics

1

Injury Biomechanics

R. Bertucci , R. Prabhu , S. Clark , M. Horstemeyer , J. Liao , and L. Williams 1

1

1

1

1

1

Mississippi State University, Starkville, MS

G. Danchik , C. DiDomenico , and E. Kennedy 1

P-Th-225 Influence of Age and Gender on Lateral Cervical Impact Response and Injury Tolerance

1

1

Bucknell University, Lewisburg, PA

1

Biomechanical Consultants of California, Davis, CA

P-Th-226 Identification of Trauma-Related Biomarkers Following Torsional Indirect Traumatic Optic Neuropathy (TITON) B. Asemota1, R. Glickman1,2, and M. Reilly1 University of Texas San Antonio, San Antonio, TX, 2University of Texas Health Science Center at San Antonio, San Antonio, TX

P-Th-214 Sub-rupture Trauma of Blast Overpressure

1

J. Hernandez1

P-Th-227 Blast Induced Traumatic Brain Injury: Detection Through Immunocytochemistry and MALDI

1

UTSA, Houston, TX

P-Th-215 Intracranial Deformation Sensor for Blast-Induced Traumatic Brain Injury S. Song , A. Kim , T. Zhang , N. Race , , Y. Gu , R. Shi , and B. Ziaie 1

1

1

1 2

1

1

1

Purdue University, West Lafayette, IN, 2Indiana University School of Medicine, Indianapolis, IN

1

P-Th-216 Evaluation of Human Body and Anthropomorphic Test Device (ATD) Injury Responses to Underbody Blast (UBB) Events C. Weaver1, K. Danelson1, and J. Stitzel1 1

P-Th-217 Injury Simulation In Vivo in Diabetic Foot 1

Virginia Tech - Wake Forest University, School of Biomedical Engineering and Sciences, Blacksburg, VA

Virginia Tech-Wake Forest University, Blacksburg, VA

P-Th-219 Quantification of Toy Sword Kinematics with Male and Female Pediatric Volunteers S. Beeman1, S. Rowson1, and S. Duma1

C. Mahaffey1, B. Weed1, S. Patnaik1, J. Liao1, R. Prabhu1, and L. Williams1 Mississippi State University, Starkville, MS

P-Th-229 The Effect of Acoustic Pollution on Marine Mammals S. Clark1,2, R. Bertucci1,2, J. Liao1,2, R. Prabhu 1,2, and L. Williams1,2 Mississippi State University, Starkville, MS, 2Center for Advanced Vehicular Systems, Starkville, MS

1

P-Th-230 Determination of Empirical Relations Between Shock Tube Geometry and Pressure Profiles A. Robbins1, P. Anumolu1, R. van Loon2, and M. Moreno1 Texas A&M University, College Station, TX, 2Swansea University, Swansea, United Kingdom

1

Virginia Tech - Wake Forest University, Center for Injury Biomechanics, Blacksburg, VA

P-Th-220 Stress State and Strain Rate Dependency in Porcine Lung Parenchyma 1

)

1

American Orthopaedic Biomechanics Research Institute, Atlanta, GA

B. Cobb1, S. Rowson1, and S. Duma1

1

University of Texas at San Antonio, San Antonio, TX, 2USAISR Ft. Sam Houston, San Antonio, TX, 3Ophthalmology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 4Biomedical Engineering University of Texas at San Antonio; Visual Science, Rosenberg School of Optometry, University of the Incarnate Word; WESMD Professional Associates; Primary Investigator with the Australian Research Council Centre of Exccellence in Vision Science (ACEVS), San Antonio, TX, 5Geologial Sciences, University of Texas at San Antonio, San Antonio, TX, 6Biomedical Engineering, University of Texas at San Antonio, San Antonio, TX

1

A. Kemper1, A. Santago1, J. Stitzel1, J. Sparks1, and S. Duma1

1

P-Th-218 Quantitative Analysis of Biomechanical Data with Random Measurement Error 1

K. Jones1, B. Lund2, R. Glickman3, W. Sponsel4, W. Gray5, and M. Reilly6

P-Th-228 Response of Isolated Whole Human Lungs in Compression: Effect of Loading Rate

Wake Forest University, Winston-Salem, NC

H. Ranu

Th

Stanford University, Stanford, CA, 2East Side College preparatory school, Stanford, CA

N. Merrier1 and S. Shimada1

P-Th-213 Comparison Of Head Impact Accelerations Based On Ground Cover Of Playgrounds 1

Poster Session

K. Laksari1, H. Shi1, L. Wu1, E. Ortega2, and D. Camarillo1

P-Th-212 A Computational Method for Analyzing Military Boot Designs at Blast Conditions 1

University of South Florida, Tampa, FL

P-Th-224 Fundamental Limitation of Conventional Helmets in Mitigating Injury

Chairs: Jennifer Currey,Yahia Al-Smadi

1

Biomechanical Consultants of California, Davis, CA

P-Th-231 Minimum Time to Collision at Braking from the 100-Car Naturalistic Driving Study J. Montgomery1, K. Kusano1, and H. Gabler1 1

Virginia Tech, Blacksburg, VA

See page 92 for Poster floor plan

BMES 2014

99

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm

Track: Biomechanics

P-Th-268 POPC Phospholipid Bilayer Failure Under Strip Biaxial Stretching Using Molecular Dynamics

Multiscale Modeling in Biomechanics

M. Murphy1, M. Horstemeyer1, S. Gwaltney1, J. Liao1, L. Williams1, and R. Prabhu1

Chairs: Rebecca Heise, Stuart Campbell

1

P-Th-258 Analysis of Toe-In Gait Modification for Patients with Knee Osteoarthritis

P-Th-269 Volume Decrease of Schlemm's Canal in an FEA Model of Elevated IOP in the Human Eye

T. Schlotman1, P. Shull2, and J. Reinbolt1 The University of Tennessee, Knoxville, TN, 22Shanghai Jiao Tong University, Shanghai, China, Shanghai, China, People's Republic of

1

Poster Session

Th

P-Th-259 Viscoelasticity of Tau Proteins Leads to Strain Rate-Dependent Breaking of Microtubules during Axonal Stretch Injury: Predictions from a Mathematical Model H. Ahmadzadeh1, D. Smith1, and V. Shenoy1 1

P-Th-260 Multi-Scale Finite Element Modeling of Human Tympanic Membrane in Normal and Diseased Ears S. Jiang , X. Wang , and R. Gan 1

1

1

Virginia Tech- Wake Forest University Center for Injury Biomechanics, Winston-Salem, NC

P-Th-263 Use of Simplified Vehicle Finite Element Models to Assess Occupant Injury in Crash Reconstructions J. Gaewsky1,2, C. Weaver1,2, A. Weaver1,2, K. Danelson1,2, and J. Stitzel1,2 Virginia Tech - Wake Forest University Center for Injury Biomechanics, Winston-Salem, NC, Wake Forest School of Medicine, Winston-Salem, NC

P-Th-264 Microstructure-Sensitive Investigation of Age-Related Changes in Pediatric Long Bone D. Christe , S. Reddy , A. Kontsos , and S. Balasubramanian 1

2

1

2

Drexel University, Philadelphia, PA, 2Drexel University, School of Biomedical Engineering and Health Systems, Philadelphia, PA

1

P-Th-265 Building Three-Dimensional Statistical Shape Models of Human Liver Y-C. Lu1 and C. Untaroiu1 1

Virginia Tech and Wake Forest University, Blacksburg, VA

P-Th-266 Development Of An Atlas-Based Finite Element Head Model L. Miller1, J. Urban1, E. Lillie1, and J. Stitzel1 Virginia Tech-Wake Forest School of Biomedical Engineering and Sciences, Winston-Salem, NC

1

P-Th-267 A Multiscale Approach For The Simultaneous Analysis Of Continuum And Micro-FE Models J. Johnson1 and K. Troy1 1

Worcester Polytechnic Institute, Worcester, MA

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

100

P-Th-168 Response of Trabecular Bone to Elevated Loading Frequencies Stevens Institute of Technology, Hoboken, NJ

P-Th-169 Characterization of a Multi-Strain Profile for Cellular Mechanotransduction Studies The University of Akron, Akron, OH, 2The University of Alabama at Birmingham, Birmingham, AL

1

S. Schoell1, A. Weaver1, and J. Stitzel1

2

Chairs: Rita Issa

J. King1, K. Shah1, P. Sethu2, and M. Saunders1

UCSD, La Jolla, CA

P-Th-262 Development of Age and Sex-Specific Thorax Finite Element Models

1

University of Texas at San Antonio, San Antonio, TX

Track: Biomechanics, Orthopaedic and Rehabilitation Engineering

1

A. B. Ramachandra1, A. Kahn1, and A. Marsden1

1

1

H. Sidoti1, A. Ritter1, and A. Valdevit1

University of Oklahoma, Norman, OK

P-Th-261 A Multiscale Framework for Simulation of Hemodynamics in a PatientSpecific Coronary Artery Bypass Graft Surgery 1

R. Wilkes1 and M. Reilly1

Musculoskeletal Biomechanics

University of Pennsylvania, Philadelphia, PA

1

Mississippi State University, Mississippi State, MS

BMES 2014

P-Th-170 Loading And Zoledronic Acid Protect Against Disuse-Induced Bone Strength Loss In The Femoral Neck J. Brezicha1, R. Boudreaux1, S. Lenfest1, A. Narayanan2, S. Bloomfield1, and H. Hogan1 Texas A&M University, College Station, TX, 2Texas A&M Health Science Center, College Station, TX

1

P-Th-171 Development and Characterization of a Pure Uniaxial Microloading Device for Biologic Testing J. King1, D. Hayes1, J. McPherson1, S. York1, and M. Saunders1 1

The University of Akron, Akron, OH

P-Th-172 Assessment of Total Shoulder Arthroplasty Glenoid Stability During Simulated Rocking Horse Motion S. Helms1, G. Colbath2, J. Gagliano3, R. Hawkins2, L. Pietrykowski1, A. Barrett1, B. Przestrzelski1, and J. DesJardins1 Clemson University, Clemson, SC, 2Steadman Hawkins, Greenville, SC, 3Steadman Hawkins, Denver, CO

1

P-Th-173 Laserectomy of the Human Spinal Disc to Relieve Low-back Pain - A Technique H. Ranu1 1

American Orthopaedic Biomechanics Research Institute, Atlanta, GA

P-Th-174 Cadaveric Thumb-tip Forces Produced by Extrinsic and Intrinsic Muscles are More Sensitive to Joint Angles than Muscle Moment Arms and Bone Lengths J. Towles1 and V. Hentz2 1

University of Wisconsin-Madison, Madison, WI, 2Stanford University, Redwood City, CA

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

2014 | october 23 | Thursday

- 10:30am, 3:30pm - 4:30pm

P-Th-175 Osteocytes’ Response to Mechanical Loading Supports Breast Cancer Cell Growth and Migration

P-Th-185 An Experimental and Theoretical Model of Simplified Childbirth

Y-H. Ma1 and L. You1

1

1

A. Baumer1, A. Lehn1, J. Grotberg2, and M. Leftwich1 The George Washington University, Washington, DC, 2University of Michigan, Ann Arbor, MI

University of Toronto, Toronto, ON, Canada

P-Th-176 Bisphosphonate Treatment During Initial Unloading Protects Against Bone Loss for Second Unloading S. Lenfest1, J. Brezicha1, R. Boudreaux1, C. Schaefer1, S. Bloomfield1, M. Allen2, and H. Hogan1 Texas A&M University, College Station, TX, 2Indiana University School of Medicine, Indianapolis, IN

P-Th-186 Mathematical Rendering of Trabecular Bone: Orientation Distribution of Trabeculae A. Morshed1, J. Wang2, X. Guo2, and X. Wang1 University of Texas at San Antonio, San Antonio, TX, 2Columbia University, New York City, NY

1

1

P-Th-177 Tribology of IL-1 Stimulated Cartilage Explants: Restoration of Chondroprotection by rhPRG4 K. Larson1, K. Elsaid2, B. Fleming1, T. Schmidt3, and G. Jay1 Brown University, Providence, RI, 2MCPHS University, Boston, MA, 3University of Calgary, Calgary, AB, Canada

1

P-Th-178 Development and Validation of Finite Element Model of a 16-Year Old Osteo-Ligamentous Thoracic Spine P. Hadagali1 and S. Balasubramanian1 1

Drexel University, Philadelphia, PA

P-Th-179 Mechanical Characterization of Gough Island Mice Femora

)

P-Th-187 Effect of Osteoactivin on the Mechanical Properties of Mouse Bone D. Hayes1, K. Novak2, F. Safadi2, and M. Saunders1 1

University of Akron, Akron, OH, 2Northeast Ohio Medical University, Rootstown, OH

P-Th-188 Biomechanical Effects Of Angled Screw Placement On The Fixation Stability Of Long Bone Shaft Fractures B. Nguyen1 and H. Vo1 1

Mercer University, Macon, GA

P-Th-189 Mathematical Analysis Of The Fatigue Failure Of An Intramedullary Rod Distal Locking Screw D. Bailey1, J. Kadlowec1, and D. Brennan2 1

Rowan University, Glassboro, NJ, 2Rowan University, Rowan University, NJ

D. Gerber1, C. Haben1, C. Vinyard2, and M. Saunders1 1

University of Akron, Akron, OH, 2Northeast Ohio Medical University, Rootstown, OH

P-Th-180 Comparing Cartilage T2 Relaxation Times and Joint Contact Pressures of Normal and Injured Wrists I. Chappell , P. Lee , T. McIff , E. Toby , and K. Fischer , 1

1

2

2

2

1 2

University of Kansas, Lawrence, KS, 2University of Kansas Medical Center, Kansas City, KS

P-Th-181 The Biomechanical Effect of Stabilizing Material for Dynamic Compression Plate on Human Cadaveric Humerous V. Nguyen1 and H. Vo1 1

Biomedical Engineering Education Chairs: John Desjardins, Craig Goergen P-Th-663 A New Model For Introductory Biomedical Engineering Education Emphasizing Clinical Innovation S. Sridhar1, M. Doshi1, S. Sridhar2, A. Nguyen1, N. Pendyala1, N. Jamali1, and V. Pizziconi1 Arizona State University, Tempe, AZ, 2University of Arizona College of Medicine - Phoenix, Phoenix, AZ

1

Mercer University, Macon, GA

P-Th-182 Determination of the Mechanical Properties of the Porcine Temporomandibular Joint Disc in Unconfined Compression at Slow Strain Rate R. Mortimer1, J. Lowe1, and A. Almarza1 1

Track: Biomedical Engineering Education (BME)

University of Pittsburgh, Pittsburgh, PA

P-Th-664 Service Learning Projects to Engage Students in Biomedical Engineering at a School which Does Not Offer a Biomedical Engineering Degree J. Rey1, O. Ledezma1, D. Won1, J. Castaneda1, A. Nabilsi1, E. Orellana1, and M. Mo1 1

California State University Los Angeles, Los Angeles, CA

P-Th-183 Mapping Biomechanical Properties of Mice Articular Surfaces Using Indentation: Preliminary Results

P-Th-665 A Comprehensive Meta-analysis of Skeletal Muscle Architecture Performed by Undergraduate BME Course

J-F. Lavoie1,2, S. Sim3,4, A. Moreau2,5, C-É. Aubin5,6, E. Quenneville7, M. Garon7, and M. Bushmann3

C. Pelland1, B. 42801, M. 42801, K. Virgilio1, J. Miller1, J. Goetschius1, L. Slater1, G. Norte1, A. Stern1, and S. Blemker1

CHU Ste-Justine/Université de Montreal, Montreal, QC, Canada, 2Universite de Montreal, Montreal, QC, Canada, 3Polytechnique Montreal, Montreal, QC, Canada, Montreal, QC, Canada, 4Biomomentum, Laval, QC, Canada, 5CHU Ste-Justine Research Center, Montreal, QC, Canada, 6Polytechnique Montreal, Montreal, QC, Canada, 7Biomomentum Inc, Laval, QC, Canada

1

1

P-Th-184 Computational Modeling of Wound Healing Based on Continuum Mixture Theory M. Rahman1, J. Zhou2, A. Nordquist1, and Y. Feng1 1

University of Texas, San Antonio, TX, 2University of Texas, Austin, TX

University of Virginia, Charlottesville, VA

P-Th-666 Multiphysics Simulation of the Krogh Tissue Cylinder System for Undergraduate Education D. Castañeda1 and B. Hawkins1 1

San Jose State University, San Jose, CA

P-Th-667 Creating a World Class Institute for Biomedical Engineering and NanoBiomedicine in Saudi Arabia H. Ranu1, A. Almejrad1, and K. Al-ibrahim1 1

University of Hail, Hail, Saudi Arabia

See page 92 for Poster floor plan

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101

Poster Session

Th

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-668 Establishment of an Interdisciplinary Biomedical Engineering Programme In Nigeria: Preliminary Observations From The University Of Lagos

P-Th-680 Using Social Media to Communicate Science to the Public: A Case Study of Science Sunday

A. Osuntoki1, O. Olawale1, E. Ajibola1, C. Esezobor1, and S. Nwaneri1

R. Bowles1,2

1

University of Lagos, Lagos, Nigeria

P-Th-669 A Tutoring Program for First Semester BME Students D. Gaitan-Leon1, P. Navas1, and J. Briceno1 1

Universidad de los Andes, Bogota, Colombia

P-Th-670 A Model for a Successful Collaborative Capstone Design Course M. Oden1, E. Richardson1, G. Woods1, A. Dick1, and M. O'Malley1 1

Poster Session

Th

Rice University, Houston, TX

P-Th-671 Best Practices in Teaching Entrepreneurship to Bioengineers: An Evaluation of Two New Overseas Medical Entrepreneurship Fellowship Programs Based in Ireland and Denmark G. Smith 1

1

Arizona School of Dentistry and Oral Health, Mesa, AZ

P-Th-672 Preliminary Experience in Flipping Biothermodynamics J. Patzer II1, R. Clark1, and M. Besterfield-Sacre1 1

University of Pittsburgh, Pittsburgh, PA

P-Th-673 Inquiry-Based Education of Fluid Mechanics Principles Using Hemodynamics A. Rocheleau1, C. Wilson2, S. Archer1, and M. King1 1

Cornell University, Ithaca, NY, 2Southside High School, Elmira, NY

1

Duke University, Durham, NC, 2ScienceSunday, Durham, NC

P-Th-681 Inquiry Based Additive Manufacturing: Bridging the Gap Between Advanced Techniques and the Classroom J. Jones1, E. Sharpsteen2, C. Schaffer1, and N. Nishimura1 1

Cornell University, Ithaca, NY, 2Onondaga High School, Onondaga, NY

P-Th-682 A Novel Online/Onsite Lab Course in Biomedical Engineering Practice and Innovation E. Logsdon1, A. Maybhate1, and E. Haase1 1

Johns Hopkins University, Baltimore, MD

)

P-Th-683 The DREAM in Teaching Computational Molecular Systems Biology K. Naegle1 1

Washington University in St Louis, St Louis, MO

P-Th-684 CANCELLED BY AUTHOR P-Th-685 Developing a Transmedia Archival Exhibit for Artificial Hearts: Genuine Stories A. Chang1, M. Han1, E. Statham1, S. Igo2, and J. Grande-Allen1 Rice University, Houston, TX, 2Houston Methodist DeBakey Heart & Vascular Institute, Houston, TX

1

P-Th-674 The DEN (Design and Entrepreneurship Network): A Multi-disciplinary Program to Develop and Apply Entrepreneurship Experiences for BME Students

P-Th-686 A BME based Inquiry Module: Gelatin and Chemical bonding for Healing a Wounded Soldier

B. Przestrzelski1 and J. DesJardins1

1

1

Clemson University, Clemson, SC

S. Iyer1, J. Saroka2, S. Archer1, and Y. Gao1 Cornell University, Ithaca, NY, 2Lansing High School, Lansing, NY

P-Th-675 Using Discussion Boards to Improve Student Professionalism and Field Knowledge

P-Th-687 Effective Engagement of Inquiry Based Learning in the K-12 Science Classroom: An Ex Ovo Chick Culture for the Study of Ethanol on Embryonic Development

M. Pool1, C. Peak2, J. Hale2, and A. Sieving2

C. Gregg1, J. Browne2, S. Archer1, and J. Butcher1

University of Illinois at Urbana-Champaign, Urbana, IL, 2Purdue University, West Lafayette, IN

1

1

P-Th-676 Design and Development of a Laser-CT: A Medical Imaging Training System J. Fang1, M. Lupp1, and W. Zhao1 1

University of Miami, Coral Gables, FL

Cornell University, Ithaca, NY, 2Binghampton City School District, Binghamton, NY

P-Th-688 Breast Tissue Engineering Module for Girl Scout STEM Career Enrichment Event S. Rowlinson1, W. Bridges1, and K. Burg1 1

Clemson University, Clemson, SC

P-Th-677 Using iBooks and iTunesU for a Sophomore-Level Class: Numerical Simulations in BME

P-Th-689 Designing a K-12 Outreach Activity: Newton's Laws of Motion

R. Hart1

1

1

The Ohio State University, Columbus, OH

V. Alphonse1, S. Beeman1, and S. Duma1 Virginia Tech - Wake Forest University Center for Injury Biomechanics, Blacksburg, VA

P-Th-678 How Broad Should Biomedical Engineering Educational Programs Be?

P-Th-690 Introducing Biomedical Engineering to a K-8 Audience using a Scalable, Hands-On Biomaterial Testing and Design Module

P. Johansen1

T. Dorsey1

1

Aarhus University, Aarhus N., Denmark

P-Th-679 Effects of Audience Response Systems on Student Attendance and Participation C. Goergen1 1

Purdue University, West Lafayette, IN

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

102

BMES 2014

1

Rensselaer Polytechnic Institute, Troy, NY

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

)

P-Th-691 Research-Intensive Community to Create a Large-Scale, Low-Cost Undergraduate Research Program R. Dongaonkar1, R. Stewart1, and C. Quick1 1

2014 | october 23 | Thursday

- 10:30am, 3:30pm - 4:30pm P-Th-78 Novel Device to Diagnose Otitis Media Using Spectroscopy and Digital Imaging K. Longo1, D. Peterson, PhD, MS1, and T. Valdez, MD2 University of Connecticut Health Center, Farmington, CT, 2Connecticut Children's Medical Center, Hartford, CT

1

Michael E. DeBakey Institute, Texas A&M University, College Station, TX

P-Th-692 Early Virtual Design Experience Enhances Relevance of Courses in BME Curriculum

P-Th-79 Reduced Field Curvature with Curved Sample Chamber in Wide Field-ofView Fluorescence Imaging for Point-of-Care CD4 Test

M. Caplan1, D. Frakes1, J. La Belle1, and V. Pizziconi1

M. Shourav1, M. Kim1, and J. Kim1

1

Arizona State University, Tempe, AZ

1

Track: Biomedical Imaging and Optics, Device Technologies and Biomedical Robotics

Diagnostic Devices and Biosensors Chairs: Elizabeth Vargis P-Th-70 Optical Skin Perfusion Monitor for Correction of Circulating Indocyanine Green Concentration Measured with a Skin Probe Y-H. Peng1 and J-M. Maarek1 1

Kookmin University, Seoul, Korea, Republic of

Track: Biomedical Imaging and Optics

Imaging Applications

)

P-Th-621 Identifying PET/MRI Parameters for Early Treatment Response in Renal Cell Carcinoma J. Antunes1, S. Viswanath2, A. Sher2, N. Avril2, and A. Madabhushi1 Case Western Reserve University, Cleveland, OH, 2Case Western Reserve University, CLEVELAND, OH

1

University of Southern California, Los Angeles, CA

)

P-Th-71 Enhanced Interferometric Detection of Individual Nanorods for Multiplexed Sensitive Molecular Assays

P-Th-622 Hyperspectral Imaging of Cardiac Ablation Lesions

D. Sevenler1, G. Daaboul1, R. Adato1, and S. Unlu1

1

1

Poster Session

Chairs: Walter O'Dell

Boston University, Boston, MA

D. Gil1, L. Swift1, R. Mazhari1, and N. Sarvazyan1 The George Washington University, Washington, DC

P-Th-72 A Colorimetric Quantification Method For Immunochromatographic Assays

P-Th-623 Automatic Quantification of Endothelial Nitric Oxide Levels in a Microvessel with and without Tumor Cell Adhesion

J. Park1

J. Wei1, L. Zhang1, and B. Fu1

1

Kyungil University, Gyeongsan-si, Korea, Republic of

1

The City College of the City University of New York, New York, NY

P-Th-73 Rapid, Single-step, Droplet-based Bacterial Assay on a Nanofibrous Substrate

P-Th-624 Measurement of Cardiomyocyte Contractility Parameters in Biomimetic Microenvironment Using Image Registration

A. Nicolini1, C. Fronczek1, and J-Y. Yoon1

J. Teo1, N. AlWahab1, and N. Christoforou1

1

The University of Arizona, Tucson, AZ

1

P-Th-74 Optical Detection of Clot Contractile Forces

P-Th-625 A Multimodal Noninvasive Medical Imaging Phantom Material: Mechanical and Imaging Properties

N. Taparia1, L. Ting1, A. Smith1, and N. Sniadecki1 1

University of Washington, Seattle, WA

B. Belmont1, W. Li1, and A. Shih1

P-Th-75 Chemical Signal Amplification for Paper-Based Assays for Influenza A Detection K. Abe1 and P. Yager1 University of Washington, Seattle, WA

1

University of Michigan, Ann Arbor, MI

P-Th-626 A Multi-Modality Imaging Approach to Generate a CAD Dataset of the 5th Percentile Female for Modeling Applications M. Davis1, J. Stitzel1, and F. Gayzik1

1

P-Th-76 Multi-branched Gold Nanoparticles For The Detection Of EGFR On The Surface Of Esophageal Epithelial Cells Using Surface Enhanced Raman Scattering J. Johnston1, E. Taylor1, R. Gilbert1, and T. Webster1 1

Khalifa University, Abu Dhabi, United Arab Emirates

1

Wake Forest University - Virginia Tech Center for Injury Biomechancis, Winston Salem, NC

P-Th-627 Numerical FSI Simulations of Acoustic Radiation Force Impulse on Human Aortas with Atherosclerotic Plaque H. Li1, K. Lin1, and D. Shahmirzadi1

Northeastern University, Boston, MA

1

Stevens Institute of Technology, Hoboken, NJ

P-Th-77 Visual Detection of Akt-mTOR-HIF-1 Signaling Pathway in Living Cell Using the Hairpin DNA Modified Gold Nanoparticle Beacon

P-Th-628 Optical Spectroscopy and Narrowband Imaging for Improved Identification of the Parathyroid Glands

S. Li1 and Y. Gu1

L. Higgins1, T. Davidov2, and M. Pierce1

1

China Pharmaceutical University, Nanjing, China, People's Republic of

Rutgers, The State University of New Jersey, Piscataway, NJ, 2Robert Wood Johnson University Hospital, New Brunswick, NJ

1

See page 92 for Poster floor plan

BMES 2014

103

Th

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-629 Studying Thermo-Mechanical Effects of Pulsed Laser Irradiation on Tissues

P-Th-640 Quantifying Biological Functions Using Fluorescent Dyes in 3D Spheroids

M. Ganguly1 and K. Mitra1

E. Leary1 and J. Morgan1

1

Florida Institute of Technology, Melbourne, FL

1

Track: Biomedical Imaging and Optics

C. Hans1, C. McCollum1, M. Bondesson1, J-A. Gustafsson1, S. Shah1, and F. Merchant1

Chairs: Tilo Winkler

1

C. Passaglia1, E. Stevenson1, E. Greenberg1, D. Richards1, and B. Madow1 1

Th

P-Th-641 Automated Quantification of Caudal Vein Plexus in Zebrafish to Study Vascular Disruptors

Image Processing and Analysis P-Th-630 Image Processing Algorithm for Automated Grading of Vitreous Haze

Poster Session

Brown University, Providence, RI

University of South Florida, Tampa, FL

P-Th-642 Surface Data of the Human Body Acquired Using Long Range Three Dimensional Laser Scanners D. Schwartz1,2, N. Hristov3, and F. Gayzik1,2 Wake Forest University School of Medicine, Winston-Salem, NC, 2Virginia Tech - Wake Forest University School of Biomedical Engineering and Sciences, Winston-Salem, NC, 3 Center for Design Innovation, Winston-Salem, NC 1

P-Th-631 Prediction Model Using Clinical and MRI-based Features for Pelvic Organ Prolapse Diagnosis S. Onal1, S. Lai-Yuen2, P. Bao2, A. Weitzenfeld2, and S. Hart2 Southern Illinois University – Edwardsville, Edwardsville, IL, 2University of South Florida, Tampa, FL

1

P-Th-632 Filtered Back-Projection With A Precise Weighting Function For Photoacoustic Image Reconstruction H. HUANG1, G. Bustamante1, R. Peterson1, and J. Ye1 1

University of Houston, Houston, TX

University of Texas at San Antonio, San Antonio, TX

Track: Biomedical Imaging and Optics

Magnetic Resonance Imaging Chairs: Stephen LeConte P-Th-643 Enhanced Delivery and Imaging of Neurotherapeutics via US, MRI, SPECT and Acoustically Activated Nanoparticles

P-Th-633 Automatic Initialization of 2D/3D Medical Image Registration Using A Hybrid Classifier

M. Valdez1, E. Yoshimaru1, S. Yuan1, A. Halawani1, P. Ingram1, T. Matsunaga1, R. Witte1, L. Furenlid1, and T. Trouard1

J. Wu1, E. Abdel Fatah1, and M. Mahfouz1

P-Th-644 Nephrotoxicity Assessment of A Novel Graphene-Based Magnetic Resonance Imaging Contrast Agent in Chronic Renal Failure Rodent Models

1

The University of Tennessee, Knoxville, TN

P-Th-634 Organ-Wide Multiscale Vessel filtering for Cerebral Vasculature Modeling C-Y. Hsu1, B. Schneller1, and A. Linninger1 1

N. Zweifel1, R. Strahle1, S. Scheidegger1, R. Fuchslin1, and S. Rhodes2 Zurich University of Applied Sciences, Winterthur, Switzerland, 2Grand Valley State University, Grand Rapids, MI

1

P-Th-636 Automation of Microcapsule Evaluation and Characterization for Use in Islet Transplantation R. Krishnan1, M. Alexander1, K. Chan1, A. Wolcott1, C. Foster III1, and J. Lakey1 University of California Irvine, Orange, CA

Y. Jiang1 1

University of Toronto, Toronto, ON, Canada, 2Ryerson University, Toronto, ON, Canada

P-Th-639 Laser Diffraction Imaging of Bacteria K. Konnaiyan , A. Lam , D. Covert , and A. Sebuka 1

1

Texas A&M University, College Station, TX, 2University of Texas Southwestern Medical Center, Dallas, TX, 3Philips Medical Systems, Cleveland, OH

1

P-Th-646 Temporal SNR of Myocardial ASL does not Increase with Improved Spatial Consistency of Background Suppression T. Jao1, H. Do1, and K. Nayak1

1

1

University of South Florida, Tampa, FL

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

104

BMES 2014

University of Southern California, Los Angeles, CA

P-Th-647 Adapting 1H Receivers for Multi-Nuclear MRS by Frequency Translation S. Ogier1, N. Hollingsworth1, J. Rispoli1, M. McDougall1, and S. Wright1 1

S. Hashemi Amroabadi1, S. Khayyer2, A. Quach2, H. Farooq2, A. Bargriz Farshi2, and S. Beheshti2 1

J. Rispoli1, I. Dimitrov2,3, S. Cheshkov2, S. Ogier1, C. Malloy2, S. Wright1, and M. McDougall1

University of Central Oklahoma, Edmond, OK

P-Th-638 Electron Microscopy Image Restoration and Resolution Improvement using an Example-based Super-Resolution Algorithm

Stony Brook University, Stony Brook, NY

P-Th-645 Array Coil for Carbon-13 MRS at 7 Tesla

1

P-Th-637 Guidewire Enhancement Using a Multi-stage Order Statistic Filter in Digital X-ray Fluoroscopy

University of Arizona, Tucson, AZ

S. Lee1, J. Toussaint1, S. Kanakia1, S. Chowdhury1, W. Moore1, K. Shroyer1, and B. Sitharaman1 1

University of Illinois at Chicago, Chicago, IL

P-Th-635 The Use of Stochastic Resonance to Improve Detectability in CT Images

1

1

Texas A&M University, College Station, TX

P-Th-648 Mathematical Modeling of Multiply Connected Structures for Elastographic Imaging B. Schwartz1, Z. Yin1, and R. Magin1 1

University of Illinois at Chicago, Chicago, IL

P-Th-649 Preparation of Cationic Macrocyclic Ligand for MR Imaging of Cartilage K. Nwe1 1

1

University of Pennsylvania, Philadelphia, PA

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

P-Th-650 Nanomanufacturing of Targeted Rod- and Spherical Shaped Viral Nanoparticle MRI Contrast Agents for In Vivo Detection of Atherosclerotic Plaques in Mice M. Bruckman1, L. Randolph1, A. VanMeter1, K. Jiang1, E. Simpson2, L. Luyt2, X. Yu1, and N. Steinmetz1 Case Western Reserve University, Cleveland, OH, 2The university of western ontario, London, ON, Canada

1

P-Th-651 Improving Low-SNR Perfusion and Inflammation MRI with a Constrained Model-Based Reconstruction S. Fielden1, L. Zhao1, M. Wintermark1, A. Klibanov1, B. French1, F. Epstein1, and C. Meyer1 1

University of Virginia, Charlottesville, VA

P-Th-652 Design of Interpolymer Complex-Superparamagnetic Iron Oxide Nanoparticles (IPC-SPIOs) with Potential for MR Molecular Imaging E. Yoo1 1

Binghamton University (SUNY), Binghamton, NY

- 10:30am, 3:30pm - 4:30pm P-Th-659 Fast Imaging of Cancer Receptor Expression using Zwitterionic Tracers X. Xu1, R. Patil1, H. Choi2, and K. Tichauer1 Illinois Institute of Technology, Chicago, IL, 2Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA

1

P-Th-660 Prussian Blue Nanoparticles For Multimodal Imaging Of Pediatric Brain Tumors M. Dumont1, S. Yadavilli1, R. Sze1,2, J. Nazarian1,2, and R. Fernandes1,2 Children's National Health System, Washington, DC, 2George Washington University, Washington, DC

1

P-Th-661 Discoidal Polymeric Nanoconstructs For Multimodal Cancer Imaging J. Key1, A. Palange1, S. Aryal1, C. Stigliano1, and P. Decuzzi1 1

Houston Methodist Research Institute, Houston, TX

F. Mokhtari1, E. Davenport1, J. Urban1, C. Whitlow1, S. Natarajan2, J. Stitzel1, and J. Maldjian1 Wake Forest University, Winston Salem, NC, 2Indiana University, Bloomington, IN

1

P-Th-654 Optimization of Oxygen Extraction Fraction in MRI Human Brain Using Augmented Lagrangian Joint Estimation

Poster Session

P-Th-662 Progressive Tumor Accumulation of Positron Emitting Magnetic Nanoconstructs S. Aryal , J. Key , C. Stigliano , D. Lee , and P. Decuzzi 1

P-Th-653 Classifying Head-Impact Related Changes in Brain Connectivity after a Single Season of High School Football: A Support Vector Machine Recursive Feature Elimination Approach

2014 | october 23 | Thursday

1

1

1

1

Th

1

Houston Methodist Research Institute, Houston, TX

Track: Cancer Technologies

Engineering of Cancer Chairs: Amit Pathak, Srivatsan Kidambi

N. Bahrami1, M. Johnston1, and Y. Jung2

P-Th-301 Extracellular Mechanical Cues Drive Vinculin Mediated PI3-kinase Signaling to Enhance Cell Invasion in 3D

Wake Forest University, Winston Salem, NC, 2Wake Forest University School of Medicine, Winston Salem, NC

M. Rubashkin1, L. Cassereau1, R. Bainer1, C. Dufort1, Y. Yui1, G. Ou1, M. Paszek1,2, M. Davidson3, Y-Y. Chen1, and V. Weaver1

1

1 3

Track: Biomedical Imaging and Optics

University of California - San Francisco, San Francisco, CA, 2Cornell University, Ithaca, NY, Florida State University, Tallahassee, FL

Molecular Probes

P-Th-302 3D Printing Biomimetic Bone Model for In Vitro Study of Breast Cancer Bone Invasion

Chairs: Beata Chertok

W. Zhu1 and L. Zhang1 1

P-Th-655 Two Photon Excitation Spectra of Proteolytic Beacons - A Preliminary Study D. Haskett1, U. Utzinger1, D. McGrath1, O. McIntyre2, and J. Vande Geest1 1

University of Arizona, Tucson, AZ, 2Vanderbilt University, Nashville, TN

The George Washington University, Washington, DC

P-Th-303 Differential Response to Matrix Rigidity Correlates with Aggressive Phenotype of Breast Cancer Cells J. Li1, Y. Wu1, M. Al-Ameen1, and G. Ghosh2 University of Michigan Dearborn, Dearborn, MI, 2University of Michigan, Dearborn, Dearborn, MI

1

P-Th-656 Development of Fibrin-Targeting Paramagnetic Nanoparticles for Brain Injury Applications K. Rumbo , V. Bharadwaj , V. Kodibagkar , and S. Stabenfeldt 1

1

1

1

1

Arizona State University, Tempe, AZ

P-Th-304 Adding a Temperature-dependent Time Delay Improves the Accuracy of Arrhenius Models of Cell Death J. Pearce1

P-Th-657 Investigating the Response of the Family of NIR aza-BODIPY-based Fluorescent Dyes to Microenvironmental Changes B. Saremi1,2, M. Wei1,2, V. Bandi3, Y. Liu1,2, B. Cheng1,2, F. D'Souza3, K. Nguyen1,2, Y. HONG1,2, and B. Yuan1,2

1

Univ. of Texas at Austin, Austin, TX

P-Th-305 Elucidating Brain Tumor-Niche Interactions In 3D Using Biomimetic Hydrogels

University of Texas at Arlington, Arlington, TX, 2The University of Texas Southwestern Medical Center at Dallas, Dallas, TX, 3University of North Texas, Denton, TX

C. Wang1, X. Tong1, and F. Yang1

P-Th-658 NIR Lead Sulfide Quantum Dots Targeted to Vascular Endothelial Growth Factor Receptor 2 for Colorectal Cancer Imaging

P-Th-306 Engineered High-throughput Cellular Models of Prostate Cancer Resistance, Dormancy and Relapse using Novel Antibiotic Hydrogels

J. Carbary1, J. Barton1, and U. Utzinger1

T. Grandhi1, T. Potta2, J. Faust1, and K. Rege1

1

University of Arizona, Tucson, AZ

1

1

1

Stanford University, Stanford, CA

Arizona State University, Tempe, AZ, 2Marlyn Nutraceuticals, Tempe, AZ

See page 92 for Poster floor plan

BMES 2014

105

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-307 Hydrogel-based Multicellular Cancer Spheroid Models for Drug Screening Applications S. Zustiak , A. Ashraf , A. Branyi , and Y. Kim 1

1

1

2

Track: Cancer Technologies, New Frontiers and Special Topics

2

Saint Louis University, St Louis, MO, 2University of Alabama, Tuscaloosa, AL

Nanotechnologies for Cancer

P-Th-308 Cell Spheroids As Microscopic Models for Macroscopic Problems M. Joyce and A. Brock 1

1

Chairs: Rohan Fernandes, Beata Chertok

1

P-Th-318 A Nanoparticle-Based Combination Chemotherapy Delivery System for Enhanced Tumor Killing by Dynamic Rewiring of Signaling Pathways

The University of Texas at Austin, Austin, TX

P-Th-309 Superior Methods To Examine Bone Tumor And Host Tissue Interactions Using Micro-Gravity Bioreactors

S. Morton1, M. Lee1, Z. Deng1, E. Dreaden1, E. Siouve1, K. Shopsowitz1, N. Shah1, M. Yaffe1, and P. Hammond1 1

A. Tondon1, C. Haase1, R. Reese1, C. Dodson1, C. Gregory2, and R. Kaunas1 Poster Session

Th

MIT, Cambridge, MA

Texas A&M University, College station, TX, 2Institute for Regenerative Medicine, Texas A&M Health Science Center, Temple, TX

P-Th-319 Characterization of Novel Chitosan/Polyelectrolyte Nanoparticles

P-Th-310 A Murine Model for Breast Microcalcifications in Radiographically Dense Mammary Tissue

M. Mertz1, B. Koppolu1, and D. Zaharoff1

1

1

L. Cole1, T. Vargo-Gogola2, and R. Roeder1 University of Notre Dame, Notre Dame, IN, 2Indiana University School of Medicine - South Bend, South Bend, IN

1

P-Th-311 Three-dimensional Microfluidic Co-culture Model of the Bone Marrow Microenvironment for the Study of Acute Lymphoblastic Leukemia

P-Th-320 Drugging Metastatic and Locally-Disseminated Solid Tumors Using RNAi Combination Chemotherapy E. Dreaden1, Y. Kong1, M. Yaffe1, and P. Hammond1 1

MIT - Koch Institute for Integrative Cancer Research, Cambridge, MA

P-Th-321 Efficacy Of Active Targeting Nanodevice For Anticancer Drug Delivery To Breast Cancer Cells

A. Bruce1, R. Evans1, R. Mezan1, K. Martin1, L. Gibson1, and Y. Yang1 1

University of Arkansas- Fayetteville, Fayetteville, AR

West Virginia University, Morgantown, WV

A. Satsangi1,2, S. Roy1, R. Satsangi3, R. Vadlamudi1, and J. Ong2 University of Texas Health Science Center at San Antonio, San Antonio, TX, 2University of Texas at San Antonio, San Antonio, TX, 3RANN Research Corporation, San Antonio, TX

P-Th-312 Effect of Methylcellulose on Breast Cancer Cellular Spheroid Biomechanics

1

J. Rodriguez-Devora1, A. Desai1, N. Nosoudi1, and D. Dean1

P-Th-322 Gold Nanoparticle Mediated Antigen and Adjuvant Delivery for Cancer Immunotherapy

1

Clemson University, Clemson, SC

P-Th-313 Extracellular Matrix Stiffness Differentially Regulates Cell Population Dynamics And Drug Response of Myeloid Leukemias J-W. Shin and D. Mooney 1

1

J. Mattos Almeida1, A. Lin1, E. Figueroa1, A. Foster2, and R. Drezek1 1

1

P-Th-323 Improving Efficiency and Reliability of Nanoparticle Amplification for Molecular Cancer Diagnostics

Harvard University, Cambridge, MA

P-Th-314 A 3D in vitro Tumor Spheroid Model to Study Spatial Variation of Protein Expression in Cancers S. Rao , P. Karande , and P. Underhill 1

1

1

M. Rahim1, R. Kota1, and J. Haun1 1

P-Th-324 Superparamagnetic Iron Oxide Nanoparticle Actuation Decreases Astrocyte Viability

Rensselaer Polytechnic Institute, Troy, NY

N. Schaub1, D. Rende1, Y. Yuan1, R. Gilbert1, and D-A. Borca-Tasciuc1 1

V. Aragon Sanabria1, S. Pohler1, E. Gomez1, and C. Dong1

)

P-Th-316 Tissue-Engineered Models of Tumor-Vascular Interactions P. DelNero , S. Verbridge , Y. Zheng , B. Kwee , A. Stroock , and C. Fischbach 2

3

1

1

Cornell University, Ithaca, NY, 2Virginia Tech-Wake Forest University, Blacksburg, VA, 3 University of Washington, Seattle, WA 1

P-Th-317 A High Throughput Platform for Assaying Cancer Cell Adhesion under Physiologic Flow A. Shearer1, V. Le1, C. Spruell1, S. Nandi1, M. Creixell1, and A. Baker1 1

University of Texas at Austin, Austin, TX

Rensselaer Polytechnic Institute, Troy, NY

P-Th-325 Polymeric Micelle as a Drug and Gene Delivery Carrier for Spinal Cord Tumor

The Pennsylvania State University, University Park, PA

1

University of California Irvine, Irvine, CA

)

1

P-Th-315 Melanoma Induces Endothelial Junction Disruption By Co-opting Endothelial Cell Contractility 1

Rice University, Houston, TX, 2Bellicum Pharmaceuticals, Houston, TX

S-J. Gwak1, J. Nice1, B. Green1, and J. Lee1 1

1

Department of Bioengineering, Clemson University, Clemson, SC

P-Th-326 The Effect of Surface Functionalization and Temperature on Nanoparticle Penetration into Tumor Spheroids A. Nagesetti1, D. Estumano2, H. Orlande2, M. Colaço2, G. Dulikravich1, and A. McGoron1 Florida International University, Miami, FL, 2Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

1

P-Th-327 Folate-targeted MMP-cleavable Nanobeacons: Toward Imaging Delivery in Solid Tumors I. McFadden1, J. Duan1, B. Fingleton1, T. Giorgio1, and J. McIntyre1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

106

BMES 2014

Vanderbilt University, Nashville, TN

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

2014 | october 23 | Thursday

- 10:30am, 3:30pm - 4:30pm

P-Th-328 Isolation of Circulating Tumor Cells Using Electrospun Nanofibers Integrated Lab-on-a-Disc

P-Th-235 Wireless Recording of Arterial Pulses

C-J. Kim1, V. Sunkara1, J. Park1, and Y-K. Cho1

1

1

Ulsan National Institute of Science and Technology, Ulsan, Korea, Republic of

P-Th-329 Conductive Polymer-Based Nanostructures for Photothermal Ablation of Cancer: Synthesis and In Vitro Evaluation T. Cantu1, K. Walsh1, V. Pattani2, J. Tunnell2, J. Irvin1, and T. Betancourt1 1

Texas State University, San Marcos, TX, 2The University of Texas at Austin, Austin, TX

P-Th-330 Optimizing Nanoparticle Transport in Tumour Extracellular Matrix: Towards Patient Specific Targeting C. Sarsons1, K. Terefe1, E. Sykes2, Q. Dai2, J. Chen2, J. Rocheleau2, D. Hwang2, D. Cramb1, G. Zheng2, W. Chan2, and K. Rinker1 1

University of Calgary, Calgary, AB, Canada, 2University of Toronto, Toronto, ON, Canada

P-Th-331 [60]Fullerenes Combined With Radiofrequency Exposure Cause Cell Death in HCC Through Apoptosis P. Gehlot1,2, Y. Mackeyev2, and S. Curley2 1

University of Michigan, Michigan, MI, 2MD Anderson Cancer Center, Houston, TX

P-Th-332 Novel Magnetic Calcium Phosphate Nanoparticles for Cancer Treatment X. Cheng and J. Salcido , 1

1 2

Southwest Research Institute, San Antonio, TX, 2University of Texas at San Antonio, San Antonio, TX

1

Columbia University, New York, NY

P-Th-334 Nanoparticle Charge Influences Serum Protein Adsorption, Circulation Time, and Biodistribution A. Bohorquez1, K. Court2, L. Santiago2, M. Latorre2, E. Mora3, E. Juan2, M. Torres-Lugo2, and C. Rinaldi1 3

P-Th-236 Border-collision Bifurcation of Calcium Cycling Dynamics in Cardiac Myocytes X. Zhao1 and E. Tolkacheva2 1

University of Tennessee, Knoxville, TN, 2University of Minnesota, Minneapolis, MN

P-Th-237 Optical Mapping of Beating Heart H. Zhang1, K. Iijima1, P. Estep1, L. Raju1, G. Walcott1, and J. Rogers1 1

University of Alabama at Birmingham, Birmingham, AL

P-Th-238 Quantitative Analysis of Electrophysiological Ventricular Heart Failure Cell Model in 1D Tissue M. Elshrif1, E. Cherry1, and P. Shi1 1

Rochester Institute of Technology (RIT), Rochester, NY

P-Th-239 The Long and Short of It A. Greer-Short1 and S. Poelzing1 1

Virginia Tech Carilion Research Institute, Roanoke, VA

P-Th-240 Non-Invasive Image-Based Assessment of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes 1

S. De Leo1, D. Bogdanowicz1, P. Chuang1, A. Dang1, H. Lu1, and L. Kam1

1

University of Texas at Arlington, Arlington, TX

C. Heylman1, R. Datta1, Y. Kurokawa1, D. Tran1, B. Conklin2, E. Gratton1, and S. George1

P-Th-333 Electrospun Fibers as a Platform for T Cell Expansion. 1

W. Shi1, C. Nguyen1, and J-C. Chiao1

University of Florida, Gainesville, FL, 2University of Puerto Rico, Mayaguez, Mayaguez, PR, University of Puerto Rico Comprehensive Cancer Center, San Juan, PR

University of California, Irvine, Irvine, CA, 2Gladstone Institutes, San Francisco, CA

P-Th-241 Classification of Atrial Fibrillation and Sinus Rhythm with a Gaussian Mixture Model T. Lye1, V. Iyer2, and C. Hendon1 1

Columbia University, New York, NY, 2Columbia University Medical Center, New York, NY

P-Th-242 The Emission Isosbestic Point of Di-4-ANEPPS as a Function of Excitation Wavelength in Myocardium H. Zhang1, J. Powell1, R. Densmore1, G. Walcott1, and J. Rogers1 1

Track: Cardiovascular Engineering

P-Th-243 Non-invasive Holter Monitor Suit for Recording Electrocardiograms in Conscious, Unanesthitized, Behaving Mice

Cardiac Electrophysiology and Mechanics

J. Marmerstein1, K. Holzem1, and I. Efimov1 1

Chairs: Charles Taylor, Milica Radisic

)

P-Th-232 Assessment of Ventricular Function in Zebrafish Heart Regeneration by Interfacing Surface Electrical Conduction with Intracardiac Hemodynamics N. Jen1, J. Lee1, H. Cao1, B. Kim2, K. Shung2, and T. Hsiai1 1

Washington University in St. Louis, St. Louis, MO

P-Th-244 Visible Light Absorbance Spectroscopy of Excised Perfused Hearts Reveals Increased Myocardial and Mitochondrial Oxygenation with Perfluorocarbon Perfusate R. Jaimes III1, S. Kuzmiak-Glancy1, R. Covian2, A. Wengrowski1, B. Glancy2, R. Balaban2, and M. Kay1

UCLA, Los Angeles, CA, 2USC, Los Angeles, CA

P-Th-233 Optically Mapping the Effects of Light-Activated Norepinephrine Release from Cardiac Sympathetic Neurons A. Wengrowski1, X. Wang1, S. Tapa1, D. Mendelowitz1, and M. Kay1 1

University of Alabama at Birmingham, Birmingham, AL

The George Washington University, Washington, DC

P-Th-234 Experimental Investigation On Spatial Dynamics Of Bifurcation To Alternans In Paced Rabbit Hearts

1 The George Washington University, Washington, DC, 2National Institutes of Health, Bethesda, MD

P-Th-245 Effects of Acellular Microheterogeneities on Macroscopic Impulse Conduction in Regimes of Normal and Reduced Excitability H. Asfour1, S. Verma1, C. Henriquez2,3, and N. Bursac1 Duke University, Durham, NC, 2Duke Univeristy, Durham NC, NC, 3Duke Univeristy, Durham, NC

1

K. Kulkarni1, R. Visweswaran1, S. Tan1, X. Zhao2, and E. Tolkacheva1 1

University of Minnesota, Minneapolis, MN, 2University of Tennessee, Knoxville, TN

See page 92 for Poster floor plan

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Poster Session

Th

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-246 Efficient Modeling of Three-Dimensional Cardiac Bidomain with Model Order Reduction

P-Th-257 Stress Production in Locally Organized, Globally Disorganized Cardiac Tissues

D. Vu1 and K. Ng1

M. Knight1 and A. Grosberg1

1

New Mexico State University, Las Cruces, NM

1

P-Th-247 The Mechanism of Reentry in an Inhomogeneous Sheet of Ventricular Myocardium S. Kandel1 and B. Roth1 1

Th

Track: Cellular and Molecular Bioengineering

Cell Adhesion and Motility

Oakland University, Rochester, MI

P-Th-248 Linking Between Cardiac trabeculation Development and Wall Shear Stress with 4-Dimenstional Single Plane Illumination Microscopy Poster Session

University of California, Irvine, Irvine, CA

Chairs: Leo Wan, Kapil Pant

J. Lee1, P. Fei1, H. Xu2, C-M. Ho1, J. Kuo2, N. Chi3, and T. Hsiai1

P-Th-418 The Effect of Exogenous Zinc Concentration on the Migration of Osteoblast-like and Osteosarcoma Cells

University of California, Los Angeles, Los Angeles, CA, 2University of Southern California, los angeles, CA, 3University of California, San Diego, La Jolla, CA

1

1

P-Th-249 Metabolic Model of Right Ventricular Dysfunction under High Afterload and Hypoxia M. Lee1, B. Faliks2, C. Scipione2, K. Koch2, A. Vo3, and K. Cook4 Mackay Memorial Hospital, HsinChu branch, Hsinchu City, Taiwan, 2University of Michigan, Ann Arbor, MI, 3Northwestern University, Chicago, IL, 4Carnegie Mellon University, Pittsburgh, PA

1

P-Th-250 Synchronization of Mechanically Coupled Cardiomyocytes on Thin Films B. Williams1 and T. Saif1 1

University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, Drexel University, Philadelphia, PA, 3Stanford University School of Medicine, Stanford, CA

1

2

P-Th-253 Quantification of Left Ventricular Pressure and Contractility as a Means to Assess Bisphenol A Cardiac Toxicity D. Brooks1, M. Kay1, and N. Posnack1

Z. Wang1, H. Yang1, T. Borg2, and B. Gao1 Clemson University, Clemson, SC, 2Medical University of South Carolina, Charleston, SC

P-Th-255 New Concept for Measuring the Forces in Mitral Valve Annuloplasty Rings S. Nielsen Skov , , D. Mathilde Røpcke , A. W. Siefert , C. Ilkjær , M. Juan Tjørnild1, A. Yoganathan3, H. Nygaard1, S. Lyager Nielsen1, and M. Jensen3 1

3

1

Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark, 2Department of Engineering, Faculty of Science and Technology, Aarhus University, Aarhus, Denmark, 3Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA

1

P-Th-256 Modulation of Mechanical Response of Micropatterned Cardiomyocytes Using Atomic Force Microscopy N. Nagarajan1, V. Vyas1, Y. Kutes1, B. Huey1, and P. Zorlutuna1 University of Connecticut, Storrs, CT

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

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3

Northeastern University, Boston, MA, 2Illinois Institute of Technology, Chicago, IL, University of Kragujevac, Kragujevac, Yugoslavia

P-Th-420 Uncovering Cell-type Specific Plasticity in Contact Guidance Efficiency Iowa State University, Ames, IA

P-Th-421 Dynein Arm Mutations Modify the Effects of Increased Viscous Forces on the Flagellar Waveform Washington University in St. Louis, St. Louis, MO

P-Th-422 A Perinuclear Actin Cap Mediates Tight Coupling Between Nucleus and Cell Migration D-H. Kim1,2 and D. Wirtz1,2 Johns Hopkins Physical Sciences – Oncology Center, Baltimore, MD, 2Johns Hopkins University, Baltimore, MD

1

P-Th-423 Investigation of the Role of ECM Mimicking Biophysical Cues and Biochemical Cueson Single Cell Migration A. Kim1, M. Traore1, E. Smith1, A. Myers1, A. Nain1, and B. Behkam1 1

George Washington University, Washington, DC

P-Th-254 Sarcomere-length Variations During In-vitro Sarcomerogenesis

1

1

1

A. Trubelja1, B. Freedman1, J. MacArthur, Jr1, M. Hast1, J. Sarver2, J. Cohen1, W. Hiesinger1, P. Atluri1, and Y. Woo3

1 2

S. Mijailovich1, M. Prodanovic1,2, M. Svicevic3, R. Gilbert1, and B. Stojanovic3

K. Wilson1, O. Gonzalez1, S. Dutcher1, and P. Bayly1

University of Utah, Salt Lake City, UT

P-Th-252 Effects Of Engineered SDF-1a On Infarcted Myocardium Under Dynamic Loading Conditions

1

P-Th-419 Molecular Model of Actin-Myosin Energy Landscapes Based on Non-Linear Cross-Bridge Stiffness

1

A. Gomez1, C. Welsh1, S. Merchant1, and E. Hsu1

1

Stony Brook University, Stony Brook, NY, 2Case Western Reserve University, Cleveland, OH, 3National Synchrotron Light Source, Upton, NY

J. Wang1, J. Petefish1, A. Hillier1, and I. Schneider1

University of Illinois at Urbana-Champaign, Urbana, IL

P-Th-251 Validation of Finite Element Models of Cardiac Structure and Kinematics via CINE, Displacement-Encoded, and Diffusion MRI. 1

D. Rammelkamp1, K. Dorst1, E. Farquhar2,3, M. Chance2,3, and Y. Meng1

Virginia Tech, Blacksburg, VA

P-Th-424 Tubulin Modification Regulates The Motility Of Axonemal Dynein J. Alper1,2, F. Decker2, B. Agana1,2,3, and J. Howard1,2 1 Yale University, New Haven, CT, 2Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, 3Missouri State University, Springfield, MO

P-Th-425 Superparamagnetic Iron Oxide Nanoparticle-labeled Cells for Magnetically Directed Cell Motility D. Sotto1, C. Jreige1, and G. Bao1 1

Georgia Institute of Technology, Atlanta, GA

P-Th-426 Signal Enhancing Effect of Serum on the Spontaneous Activity of Chick Forebrain Neuron Culture on a Microelectrode Array X. Yang1, S. Kuang1, and B. Gao1 1

Clemson University, Clemson, SC

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

2014 | october 23 | Thursday

- 10:30am, 3:30pm - 4:30pm

P-Th-427 How Actomyosin Contraction Contributes to Cancer Cell Migration in Full Confinement - A Poroelasticity-based Model

P-Th-438 Investigating Electrotaxis of the Non-Transformed MCF-10A Mammary Epithelial Cell Line

J. Wright1 and C-J. Chuong1

M. Lalli1 and A. Asthagiri1

1

University of Texas at Arlington, Arlington, TX

1

P-Th-428 Microtubules Stabilize Cell Polarity By Mediating The Localization Of Rear Signals J. Zhang1, W-H. Guo1, and Y-L. Wang1 1

Chairs: Taby Ahsan, Lauren Black III P-Th-439 Non-Invasive Measurement of Interstitial Fluid Pressure In Microscale Gels and Tissues

S. McCutcheon1, J. Uchenna2, M. Vazquez1, and S. Redenti2 The City College of New York, New York, NY, 2Lehman College, New York, NY

O. Ozsun1, R. Thompson1, J. Tien1, and K. Ekinci1 1

P-Th-430 The Organ-Specific Migratory Response of Prostate Cancer UT Arlington, Arlington, TX

)

P-Th-431 Role of Neutrophils in the On-set of Systemic Vaso-occlusion in the Blood of Sickle Cell Disease Patients M. Jimenez1 and P. Sundd1 1

University of Pittsburgh, Pittsburgh, PA

P-Th-432 H2O2-Upregulated RAGE on Aβ -Induced Oxidative Pathway and Membrane Phase Changes in bEnd.3 Cells C. Est1, H. Wang1, and J. Lee1 1

University of Missouri-Columbia, Columbia, MO

S. Wong1,2, J. Soto1,2, J. Chu1, and S. Li1,2 University of California, Berkeley, Berkeley, CA, 2University of California, San Francisco, San Francisco, CA

1

)

P-Th-441 Crosstalk of Physiological Mechanical Cues in Endothelial Cell Signaling D. Zhou1, F. Bordeleau1, J. Kohn1, A. Zhou1, B. Mason1, M. Mitchell1, M. King1, and C. Reinhart-King1 1

Cornell University, Ithaca, NY

P-Th-442 Patterned Mechanical Stiffening of PEG Hydrogels by NIR laser Y. Choi1,2, K. Hribar2, M. Ondeck2, A. Engler2, and S. Chen2

P-Th-433 Activation of CD11c Primes Foamy Monocytes for Recruitment on VCAM1 Under Shear G. Foster1, H. Wu2, and S. Simon1 1

University of California Davis, Davis, CA, 2Baylor College of Medicine, Houston, TX

University of Sydney, St Leonards, Australia, 2University of California, San Diego, La Jolla, CA

1

P-Th-443 Emerging Determinants of Cytosolic Calcium Homeostasis in the Sheared Endothelium

P-Th-434 The Role Of The Glycocalyx In Leukocyte Adhesion To Endothelial Cells In Vitro

C. Scheitlin1,2, J. Julian1,2, and R. Alevriadou1,2

K. McDonald1, S. Cooper2, and R. Leask1

P-Th-444 TLR4 is Involved in Mechanosensin

The Ohio State University, Columbus, OH, 2Davis Heart & Lung Research Institute, Columbus, OH

1

McGill University, Montreal, QC, Canada, 2McGill University, Montreal, Canada

1

M. Previtera1,2 and A. Sengupta1

P-Th-435 A Strategy for Human Tissue Self-Organization that is Robust to Heterogeneous and Changing Cell-Cell Interactions

New Jersey Neuroscience Institute at JFK Medical Center, Edison, NJ, 2Seton Hall University, Edison, NJ

1

A. Cerchiari1, J. Garbe2, M. Todhunter3, N. Jee3, K. Broaders3, M. Thomson3, M. LaBarge2, T. Desai3, and Z. Gartner3 UC Berkeley - UCSF, San Francisco, CA, 2Lawrence Berkeley National Laboratory, Berkeley, CA, 3UCSF, San Francisco, CA

1

D. Parajuli and B-M. Zhang Newby 1

The Pennsylvania State University, University Park, PA

D. McGrail1, Q. Kieu1, J. Iandoli1, and M. Dawson1 1

P-Th-437 Bioinspired Microfluidic Assay for In Vitro Modeling of LeukocyteEndothelium Interactions G. Lamberti , B. Prabhakarpandian , C. Garson , A. Smith , K. Pant , B. Wang , and M. Kiani1 2

2

2

2

3

Temple University, Philadelphia, PA, 2CFD Research Corporation, Huntsville, AL, 3Widener University, Philadelphia, PA

1

J. O'Connor1 and E. Gomez1

P-Th-446 Metastatic Cancer Mechanical Tropsim Is Controlled By Cytoskeletal Tension

1

The University of Akron, Akron, OH

1

P-Th-445 Matrix Rigidity Mediates Myofibroblast Activation by Controlling MRTF-A Signaling 1

P-Th-436 Assessing Inhibitory Capability of Zosteric Acid and Sodium Benzoate on Mouse and Human Fibroblast Cell Attachment and Proliferation 1

Poster Session

Boston University, Boston, MA

P-Th-440 Effects Of Substrate Stiffness On Direct Reprogramming From Fibroblasts To Neurons

L. Lee1, S. Bean1, S. Loh1, S. Rao1, V. Lin1, and J-C. Chiao1 1

Track: Cellular and Molecular Bioengineering

Mechanotransduction

Carnegie Mellon University, Pittsburgh, PA

P-Th-429 Chemotactic Migration of Clustered Central Nervous System Progenitor Cells 1

Northeastern University, Boston, MA

Georgia Institute of Technology, Atlanta, GA

P-Th-447 A Prestress Dependent Mechanotransduction Connecting Adhesive Receptors I. Muhamed1, J. Wu1, X. Kong1, N. Wang1, and D. Leckband1 1

University of Illinois Urbana Champaign, urbana, IL

See page 92 for Poster floor plan

BMES 2014

109

Th

Poster Session Thurs 9:30am – 5:00pm

Thursday | october 23 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-448 Syndecan-1 Mediates Endothelial Shear Mechanotransduction Response and Inflammatory Phenotype P. Voyvodic , E. Williams , R. Liu , D. Min , and A. Baker 1

1

1

1

1

1

The University of Texas at Austin, Austin, TX

P-Th-449 Determining the Relationship Between Protein Deformation and Protein Dynamics in Focal Adhesions K. Rothenberg1 and B. Hoffman1 1

Duke University, Durham, NC

P-Th-450 Antiplatelet Drug Efficacy Under Dynamic Device-Related Shear Conditions J. Sheriff1, P. Tran2, L. Valerio3, R. Ghosh1, W. Brengle2, E. Zhang1, M. Hutchinson2, D. Bluestein1, and M. Slepian2,4,5 Biomedical Engineering, Stony Brook University, Stony Brook, NY, 2Biomedical Engineering, University of Arizona, Tucson, AZ, 3Bioengineering, Politecnico di Milano, Milan, Italy, 4Sarver Heart Center, University of Arizona, Tucson, AZ, 5Stony Brook University, Stony Brook, NY

1

Poster Session

Th

Track: Cellular and Molecular Bioengineering

Cellular and Molecular Bioengineering Other Chairs: Julie Phillippi, Anand Ramasubramanian P-Th-459 Pancreatic β cell function and Mass in Pubertal Hyperinsulinemia J. Faust1, I. Malenica1, M. Doshi1, R. Stepanek1, J. Brower1, K. Sweazea1, M. Caplan1, and R. Herman1 1

Arizona State University, Tempe, AZ

P-Th-460 High Spatio-temporal ERK Activity in Response to Mechano-chemical Stimuli in Rat Mesenchymal Stem Cells A. Dharmarajan1, M. Floren2, and W. Tan2 University of Colorado at Boulder, Louisville, CO, 2University of Colorado at Boulder, Boulder, CO

1

P-Th-451 Force Generation During Primary Human Macrophage Migration on Compliant Surfaces

P-Th-461 On-Chip Multi-Frequency Current Mode Lock-in Amplifier for Impedance Sensing

L. Hind1, M. Dembo2, and D. Hammer1 1

University of Pennsylvania, Philadelphia, PA, 2Boston University, Boston, MA

N. McFarlane1 and J. Gu1

P-Th-452 Fluid Flow Affects Vascular Endothelial Cell Drug Response

1

)

P-Th-462 Kupffer Cell Mediated Cardiovascular Disease Development

L. Tamez1, R. Shepherd1, K. Fuh1, S. Baranzini2, R. Moore1, and K. Rinker1 University of Calgary, Calgary, AB, Canada, 2University of California San Francisco, San Francisco, CA

1

D. Rubenstein1 and W. Yin1 1

P-Th-453 Enhancement of Glycocalyx Mediated Endothelial Mechanotransduction Using Drug-Loaded Nanoparticles H. Homayoni , M. Cheng , R. Kumar , S. Sridhar , T. Webster , and E. Ebong 1

1

2

2

1

1

Department of Chemical Engineering, Northeastern University, Boston, MA, 2Department of Physics, Northeastern University, Boston, MA

1

P-Th-454 POR1 Geometry Sensing of Nanofiber Diameter Regulates Rac1 Activity and Osteoblast Differentiation A. Higgins1 and J. Brown1 1

The Pennsylvania State University, University Park, PA

P-Th-455 "Effects of Clinically Relevant Mechanical Forces on Vascular Smooth Muscle Cells Under Hyperglycemia: An In Vitro Dynamic Disease Model" V. Chawla1, A. Simionescu1, E. Langan III2, and M. LaBerge1 1

Clemson University, Clemson, SC, 2Greenville Health System (GHS), Greenville, SC

P-Th-456 Imaging Cellular and Molecular Stretch in an in vivo Cellular Tube Using Filamin::stFRET. J. Bouffard , A. Asthagiri , and E. Cram 1

1

1

1

Northeastern University, Boston, MA

P-Th-457 Accelerations at Sonic Frequencies Mimic Thyroid Epithelial Cells Response to TSH A. Wagner1, I. Titze1,2, and E. Sander1 1

University of Iowa, iowa city, IA, 2University of Utah, Salt Lake City, UT

P-Th-458 A Role for ER Stress in the Modulation of VCAM-1 Expression by Shear Stress and Dietary Lipoproteins K. Bailey1, Y. Wang1, G. Foster1, S. Simon1, and A. Passerini1 University of California, Davis, Davis, CA

1

University of Tennessee, Knoxville, TN

Stony Brook University, Stony Brook, NY

P-Th-463 Dictyostelium Phenylalanine Hydroxylase Is Activated by Its Substrate Phenylalanine H. Kim1, Y. Park2, Y. Kim3, Y. Yang3, Y. Kang1, S. Park1, J. Shin1, Y. Kim1, and J-W. Shin1,3,4 Department of biomedical engineering, Inje university, Gimhae-si, Korea, Republic of, 2Department of biological sciences, Inje university, Gimhae-si, Korea, Republic of, Department of health science and technology, Inje university, Gimhae-si, Korea, Republic of, 4Cardiovascular and Metabolic Disease Center /Institute of Aged Life Redesign/UHRC, Inje University, Gimhae-si, Korea, Republic of

1

3

P-Th-464 Proliferative Signals in Gradients of Soluble Growth Factors E. Gong1 and A. Asthagiri1 1

Northeastern University, Boston, MA

P-Th-465 Microfluidic Assay of Hemophilic Blood Clotting: Distinct Deficits in Platelet and Fibrin Deposition at Low Factor levels T. Colace1, P. Fogarty1, K. Panckeri1, R. Li1, and S. Diamond1 1

University of Pennsylvania, Philadelphia, PA

P-Th-466 A Rapid UV/Vis Spectroscopy Method for Detecting Protein-Centered Radicals using DMPO B. Hollins1 1

Louisiana Tech University, Ruston, LA

)

P-Th-467 Loss of Endothelial Surface Glycocalyx in Early Sepsis J. Fan , W. Yen1, M. Zeng1, J. Chen2, B. Ratliff2, J. Tarbell1, M. Goligorsky2, and B. Fu1 1

The City College of the City University of New York, New York, NY, 2New York Medical College, Valhalla, NY

1

P-Th-468 Phospholipase A2 in Aβ clearance by microglia L. Dong1, C. Est1, K. Henderson1, and J. Lee1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

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BMES 2014

University of Missouri-Columbia, Columbia, MO

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

P-Th-469 Fibronectin Decreases Fibroblast Migration After Electrical Stimulation S. Snyder1 and R. Willits1 1

P-Th-470 Increased Sphingomyelinase Activity in Sickled Red Blood Cells during Sickle Cell Disease Y. Zhang , A. Awojoodu , and A. Lane 1

1

- 10:30am, 3:30pm - 4:30pm P-Th-48 Development of A Rapid and Label-free Affinity Sensor for On-site Biomolecular Detection H. Cui1, C. Cheng1, Q. Yuan1, J. Wu1, and S. Eda1

University of Akron, Akron, OH

1

2014 | october 23 | Thursday

1

Georgia Institute of Technology, Atlanta, GA

1

University of Tennessee, Knoxville, TN

)

P-Th-49 Bioimpedance Analysis Detects Lower Leg Muscle Atrophy in Patients with Charcot-Marie-Tooth Disease J. Woods1, M. Solomito1, and E. Garibay1 1

Connecticut Children's Medical Center, Farmington, CT

Track: Device Technologies and Biomedical Robotics, Translational Biomedical Engineering

P-Th-50 Monitoring Phospholipase A2 Activity Using Gd-encapsulated Phospholipid Liposomes

Biomedical Sensors & Actuators

Z. Cheng1 and A. tsourkas1

Chairs: Samir Iqbal, Tony Akl P-Th-40 The Design and Implementation of a 4 DOF Robotic Manipulator for Automated Venipuncture Rutgers University, Piscataway, NJ

University of Pennsylvania, philadelphia, PA

Poster Session

Th

P-Th-51 An Organic Light-Emitting Diode for Oxygen Sensing Based on Phosphorescence Lifetime Y. Ando1, Y. Yanagisawa1, and K. Tsukada1 1

M. Balter1 and A. Chen1 1

1

Keio University, Yokohama, Japan

P-Th-41 Acoustic Manipulation of Protein Microcrystals for X-ray Crystallography

P-Th-52 Fluorescence Quenching by Varying Sized Gold Nanorods for Multiplexed Plasmonic Biochip

F. Guo1, J. French 2, P. Li1, Z. Mao1, N. Yennawar1, and T. Huang 1

Y. Wang1 and L. Tang1

1

Penn state university, state college, PA, 2Stony Brook University, Stony Brook, NY

1

University of Texas at San Antonio, San Antonio, TX

P-Th-42 Measurement of Blast Reflected & Incident Overpressures with the Blast Gauge TM System

P-Th-53 Study Interactions Of FvTox1 With Synthetic Peptides Using A Label-free Biosensor And Molecular Simulations

G. Lee1, U. Da Silva2, M. Ostertag3, M. Kenyon3, K. Allpress4, G. Katselis4, D. Borkholder3,5, and G. Kamimori1

B. Zhang1, B. Wang2, A. Morales1, J. Tamez-Vela1, J. Scudder1, M. Bhattacharyya2, and J. Ye1

Walter Reed Army Institute of Research, Silver Spring, MD, 2Naval Medical Research Center, Silver Spring, MD, 3BlackBox Biometrics, Inc., Rochester, NY, 4Defence Science and Technology Organisation, Edinburgh, Australia, 5Rochester Institute of Technology, Rochester, NY

1

1

P-Th-43 On Site Thermoelectric Cooling Device for Therapeutic Applications W. Hejl1, J. Lee1, N. Babaria1, S. Koshnevis1, and K. Diller1 1

University of Texas at Austin, Austin, TX

P-Th-44 Reducing Motion Artifact From Driver’s PPG Using On-line Empirical Mode Decomposition K. Lee1, C. Park1, H. Kim2, S. Kim2, and B. Lee1

P-Th-54 Readout Circuitry for Monitoring Temperature Variations in Biological Fluids F. Quaiyum1, L. Taylor1, S. Pullano2, I. Mahbub1, A. Fiorillo2, C. Britton1, and S. Kamrul Islam1 University of Tennessee Knoxville, Knoxville, TN, 2University Magna Græcia of Catanzaro, Catanzaro, Italy

1

P-Th-55 Ratiometric Nanocapsule Sensors Fabricated From Sacrificial CaCO3 Nanoparticles A. Biswas1, A. Nagaraja1, and M. McShane1 1

Gwangju Institute of Science and Technology, Gwangju, Korea, Republic of, 2Hyundai Motor Group, Hwaseong, Korea, Republic of

University of Texa at San Antonio, San Antonio, TX, 2Iowa State University, Ames, IA

Texas A&M University, College StationTX

1

P-Th-45 A Novel Wearable Cardioverter-Defibrillator for Increased Patient Compliance S. Subramanian1, P. Kang1, C-M. So1, M. Chen1, T. Lam1, C. Romanczyk1, Q. Salditch1, and A. Premkumar1 Johns Hopkins University, Baltimore, MD

1

P-Th-46 An Auditory Feedback Study on the Object Localization and Tracking System N. Mante1, G. Medioni1, A. Tanguay1, and J. Weiland1 1

University of Southern California, Los Angeles, CA

P-Th-56 A Reconfigurable Bio-Impedance Sensing Platform With Array-Based Detection Algorithm for 3D Tissue Characterization and Delineation C. Kim1, C. Zhu1, J. Zhang2, and H. Wang1 1

Georgia Institute of Technology, Atlanta, GA, 2University of Kentucky, Lexington, KY

P-Th-57 Paper-based Biosensor for Colorimetric Detection of PSA Biomarker A. Drew1 and H. Kwon11Andrews University, Berrien Springs, MI

P-Th-58 A SERS Sensing System based on Encapsulation of Gold Nanoparticles in Microporous Alginate Hydrogels

P-Th-47 Conducting Polymer PEDOT Nanofibers for Sensitive Detection of Glucose

Y-H. You1, A. Liu1, J. Roberts1, and M. McShane1

G. Yang1, K. Kampstra1, and M. Abidian1

P-Th-59 Differential Immuno-Capture Assay to Electrically Enumerate Blood Cells

1

Pennsylvania State University, State College, PA

1

Texas A&M University, College Station, TX

U. Hassan1, G. Damhorst1, T. Ghonge 1, O. Sonoiki1, L. Orlandic2, B. Reddy1, and R. Bashir1 University of Illinois at Urbana Champaign, Urbana, IL, 2University Laboratory High School, Urbana, IL

1

See page 92 for Poster floor plan

BMES 2014

111

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-60 Surface Engineering for Aptamer-Based Chemical Sensors R. Harwell1, G. Barker1, H. Marks1, G. Coté1, G. Jackson2, and M. Pishko1 1

Texas A&M University, College Station, TX, 2Base Pair Biotechnologies, Pearland, TX

P-Th- 2 Design and Characterization of an Endovascular Mechanical Thrombectomy Device J. Szafron1, A. Muschenborn1, and D. Maitland1 1

)

P-Th-61 A Study of Nano-scale Coatings on Planar Gold Microelectrodes for Bioimpedance Measurements V. Srinivasaraghavan1, J. Strobl1, D. Wang1, J. Heflin1, and M. Agah1 Virginia Tech, Blacksburg, VA

1

P-Th-3 Design and Characterization of a Resistively Heated Shape Memory Polymer Micro-Release Device L. Nash1, M. Wierzbicki1, and D. Maitland1 1

P-Th-62 A Photodiode-Integrated Microfluidic Bioreactor for Real-Time pH Monitor of Organs-on-Chip Y. Zhang , , , N. Shams , , , M. Dokmeci , , , and A. Khademhosseini , , 1 2 3

1 2 3

1 2 3

1 2 4

Harvard Medical School, Cambridge, MA, 2Brigham and Women's Hospital, Boston, MA, Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, 4Wyss Institute for Biologically Inspired Engineering, Boston, MA

1

Poster Session

Th

3

P-Th-63 In Vitro and In Vivo Evaluation of Copolymer Hydrogels as Enzyme-based Luminescence Glucose Sensors R. Unruh1, S. Nichols2, N. Wisniewski2, and M. McShane1

P-Th-65 Enhanced Electrical Label-Free Detection of Pathogens Through Isothermal DNA Amplification Using True Dual-Gated ISFETs C. Duarte-Guevara1, F-L. Lai2, C. Cheng2, B. Reddy1, E. Salm1, V. Swaminathan1, Y-S. Liu2, and R. Bashir1 1

UIUC, Urbana, IL, 2TSMC, Hsinchu, Taiwan

P-Th-66 Development of Fructose Dehydrogenase-Ferrocene Redox Polymer Films for Biosensor and Biofuel Cell Applications J. Chen1, D. Bamper1, D. Glatzhofer1, and D. Schmidtke1 1

)

L. Hobbs1, L. Shaw Klein2, W. Grande2, and G. Gdowski1 1

University of Rochester, Rochester, NY, 2Micropen Technologies, Honeoye Falls, NY

P-Th-5 Simulation of Cooling Preservation Systems for Human Hearts Destined for Transplantation A. Abdoli1, G. Dulikravich1, C. Bajaj2, D. Stowe3, and M. Jahania4 3

Florida International University, Miami, FL, 2University of Texas at Austin, Austin, TX, Medical College of Wisconsin, Milwaukee, WI, 4Wayne State University, Detroit, MI

  P-Th-6 Impact of Bifurcation Stenting on Endothelial Shear Stress H. Chen1, I. Moussa2, C. Davidson3, and G. Kassab4 Indiana Univ. Purdue Univ., Indianapolis, IN, 2University of Texas Health Science Center, San Antonio, TX, 3Northwestern University, Chicago, IL, 4IUPUI, Indianapolis, IN

1

P-Th-7 Finite Element Analysis Of A Double Opposed PLLA Helical Stent Expansion And Arterial Wall Interaction T. Welch1, S. VeeramReddy1, J. Wang1, A. Nugent1, and J. Forbess1

University of Oklahoma, Norman, OK

1

P-Th-67 Microelectronic Point-Of-Care Diagnostics For Early Phase Rickettsial Infections W. Zhang1, K. Patel1, K. Macaluso2, and A. Radadia1 1

Texas A&M University, College Station, TX

P-Th-4 Thermal Evaluation of Bipolar Radiofrequency Ablation for Treatment of Resistant Hypertension

1

Texas A&M University, College Station, TX, 2PROFUSA, Inc., South San Francisco, CA

1

Texas A&M University, College Station, TX

UT Southwestern Medical Center of Dallas, Dallas, TX

P-Th-8 Long-Term Implant Evaluation of Non-hermetic Micropackage Technology P. Wang1, S. Majerus1, J. Anderson1, M. Damaser2, C. Zorman1, and W. Ko1 Case Western Reserve University, Cleveland, OH, 2Advanced Platform Technology Center, Louis Stokes Cleveland VA Medical Center, Cleveland, OH

1

Louisiana Tech University, Ruston, LA, 2Louisiana State University, Baton Rouge, LA

P-Th-68 Specific Surface Termination of Nano-textured ZnO for Label-free Electrochemical Bio-sensing

P-Th-9 A Multilayer PDMS Microchannel Scaffold for Efficient IHC Analysis and Neural Interfacing

R. Munje1, S. Muthukumar1, M. Jacobs1, B. Quadri1, and S. Prasad1

E. Ibarra1, B. Kim1, B. Garza 1, R. Luna 1, and Y. Choi 1

1

University of Texas at Dallas, Richardson, TX

1

University of Texas – Pan American, Edinburg, TX

P-Th-69 Graphene-Based Biofet for Real–time Sensing

P-Th-10 A Polymer-based Depth-type Neural Probe with Four Sided Contacts

A. Radadia1 and B. Hou1

S. Shin1, S. Lee1, J. Jeong1, S. Ahn1, J. Kim1, K. Eom1, J. Park1, C. Koh2, H-C. Shin2, and S. Kim1

1

Louisiana Tech University, Ruston, LA

Seoul National University, Seoul, Korea, Republic of, 2Hallym University, Gangwon, Korea, Republic of

1

Track: Device Technologies and Biomedical Robotics, Cardiovascular Engineering

Cardiovascular Devices, Implantable Devices and Implantable Technologies Chairs: Dominic Nathan, Mehmet Kaya

P. Starr1,2, K. Bartels2,3, M. Agrawal2, and S. Bailey1,2 University of Texas Health Science Center at San Antonio, San Antonio, TX, University of Texas at San Antonio, San Antonio, TX, 3Southwest Research Institute, San Antonio, TX 2

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

112

BMES 2014

J. Norman1, J. Leadbetter1, H. Vihvelin1, J. Brown1, and R. Adamson1 1

Dalhousie University, Halifax, NS, Canada

P-Th-12 A Low Power Implantable Glucose Monitoring System I. Mahbub1, T. Randall1, F. Quaiyum1, and S. Islam1

P-Th-1 A Thin Film Pressure Transducer for Intravascular Blood Pressure Sensing 1

P-Th-11 Ultrasonic Dry Coupling Through Tissue

1

University of Tennessee, Knoxville, TN

P-Th-13 Biofabrication of Implantable Microfabricated Biotransducers for Dual Sensing of Glucose and Lactate A. Guiseppi-Elie1,2, O. Karunwi1,2, F. Alam1,2, and M. Gaillard1,2 Clemson University, Clemson, SC, 2Center for Bioelectronics, Biosensors and Biochips (C3B), Anderson, SC

1

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

2014 | october 23 | Thursday

- 10:30am, 3:30pm - 4:30pm

P-Th-14 Reversible and Photo-Activated Artificial Iris

P-Th-24 The Development Of A Dynamic Adaptive Driving Simulator

F. Shareef1, S. Sun1, M. Kotecha1, D. Azar1, and M. Cho1

S. Tudor1, S. Carey1, and R. Dubey1

1

University of Illinois at Chicago, Chicago, IL

1

P-Th-15 Parylene-based EC-MEMS Patency Sensor for Detection of Hydrocephalus Shunt Obstruction B. Kim1, C. Lee1, L. Yu1, and E. Meng1 1

P-Th-25 Micro Magnetic Resonance Relaxometry for Label-free, Rapid Malaria Diagnosis W. Peng1, C. Ng1, T. Kong1, L. Chen1, T. Loh2, P. Preiser1,3, and J. Han 1,4

University of Southern California, Los Angeles, CA

Singapore-Massachusetts Institute of Technology Alliance For Research And Technology(SMART), Singapore, Singapore, 2National University of Hospital, Singapore, Singapore, 3Nanyang Technological University, Singapore, Singapore, 4Massachusetts Institute of Technology, Cambridge, MA

1

P-Th-16 Implementation of a Primitive Neural Stimulator with Simulated PostSynaptic and Action Potentials A. Parodi1 and J-W. Choi1 1

University of South Florida, Tampa, FL

Louisiana State University, Baton Rouge, LA

P-Th-26 Computational Model of Light Propagation in Skin and Subcutaneous Blood Vessels for Vein Imaging Devices R. Polski1 and H. Kwon1 1

Track: Device Technologies and Biomedical Robotics

Poster Session

Andrews University, Berrien Springs, MI

Th

P-Th-27 Model And Method Of Extravasation Detection

Medical Device Development and Computational Models

J. Kantor1, M. Lasch2, and Y. Feng1

Chairs: Rafael Davalos, Sergey Shevkoplyas

P-Th-28 Analyzing Lysed Whole Blood via "Microfluidic Drifting" Based Flow Cytometery Chip"

University of Texas at San Antonio, San Antonio, TX, 2University of Texas at San Antonio, Schertz, TX

1

)

P-Th-17 Preclinical Development and Mechanical Testing of a Load Transfer Implant (LTI) for Knee Joint Arthroplasty C. Bergerson1, Z. Paulson1, C. Davis1, L. Sonoqui1, J. Hunt2, and M. Moreno1 1

Texas A&M University, College Staion, TX, 24Web, Frisco, TX

P-Th-18 Finite Element Analysis of Bore-Cone Taper Junctions in Modular Total Knee Replacements J. Hernandez , K. Snethen , and M. Harman 1

1

1

1

Clemson University, Clemson, SC

P-Th-19 Preventing Pedicle Probe Injuries During Spinal Fusion Surgeries A. Annadanam1, R. Gaddipati1, L. Herrera1, B. Isaacs1, E. Xie1, C. Andrews1, A. Malla1, and E. Schwarz1 1

Johns Hopkins, Baltimore, MD

P-Th-20 Lift Walker: Developing an Inexpensive and Lightweight Stand-Assist Device T. Rist1, C. Bateman1, J. Barretta1, J. Flores1, J. Galloway1, M. Kassner1, J. Bumgardner1, H. Lin1, T. Tan1, and R. Mulvany2 The University of Memphis, Memphis, TN, 2The University of Tennessee Health Science Center, Memphis, TN

1

P-Th-21 A Design of a Multi-degree Freedom Patient Platform for IGRT F. Zhang1, L. Sun1, S. Kuang1, S. Yu1, and Y. Feng1 1

P-Th-29 Standing Surface Acoustic Wave (SSAW) Based Multi-parametric Microflow Cytometer Y. Chen1, S. Li1, P. Li1, A. Nawaz1, L. Wang2, Y. Shariff3, and T. Huang1 Penn state university, State College, PA, 2Ascent BioNano Inc., State College, PA, 3Taibah University, Madina, Saudi Arabia

1

P-Th-30 A Wireless Sensor for Wound Strain Monitoring Using Laser Patterning on a Commercial Dressing R. Rahimi1, M. Ochoa1, and B. Ziaie1 1

Purdue University, West lafayette, IN

P-Th-31 Investigation of Wall Effects for Particle Viscometer A. Botting1, A. Plumber1, G. Bustamante1, and J. Ye1 1

University of Texas at San Antonio, San Antonio, TX

P-Th-32 Interdigitated Electrode To Treat Micro-Metastases By High-Frequency Irreversible Electroporation D. Sweeney1, E. Latouche2, P. Roberts2, E. Schmelz2, and R. Davalos1 Virginia Tech-Wake Forest University, Blacksburg, VA, 2Virginia Tech, Blacksburg, VA

P-Th-33 Mossbauer Studies of Rechargeable Na-ion Batteries for Medical Applications.

M. Luo1, R. Lee 1, C. Wong 1, R. Klatzky 2, and G. Stetten 1,2

H-Y. Hah1

University of Pittsburgh, Pittsburgh, PA, 2Carnegie Mellon University, Pittsburgh, PA

P-Th-23 Venipuncture with Vibrated Needle Yields Lower and Less Variable Corticosterone Levels in Rats R. Clement1, Z. Krieger1, E. Unger2, S. Cavigelli3, R. Sheehan1, R. Bagwell1, and M. Mulvihill1 Actuated Medical, Inc., Bellefonte, PA, 2Lebanon Valley College, Annville, PA, 3Pennsylvania State University, University Park, PA

1

Pennsylvania State University, State College, PA, 2Ascent Bio-Nano Technologies, State College, PA, 3Taibah University, Madina, Saudi Arabia, Madina, Saudi Arabia

1

1

Soochow University, SuZhou, China, People's Republic of

P-Th-22 Hand Held Force Magnifier for Microsurgery 1

A. Nawaz1, R. Nissly1, P. Li1, L. Wang2, Y. Shariff3, and T. Huang1

1

University of Tennessee Space Institute, Tullahoma, TN

P-Th-34 Designing a Low-Cost Otoscope for Developing Countries Using a Nontraditional Power Source S. Robb1, D. Wells1, J. Leipheimer1, D. Cesario1, N. Stone1, and B. Campbell1 1

Robert Morris University, Moon Township, PA

See page 92 for Poster floor plan

BMES 2014

113

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-35 Design and Construction of a Blood Glucose Meter for Use in Nigeria

P-Th-340 Anti-Cancer Drug Delivery With DNA Nano-Ball

A. Zubair1, E. Ebere-Dinnie 1, and A. Coker1

W. Sun1,2, R. Mo1,2, and Z. Gu1,2

1

University of Ibadan, Ibadan, Nigeria

P-Th-36 Design and Construction of a Portable Low Cost Electrical Safety Analyzer for Biomedical Devices A. Zubair1, O. Ibe1, and A. Coker1 1

P-Th-37 Device for Aid in Neonatal and Infant Resuscitation M. Hemani , B. Gu , B. Kim , T. Lam , and A. Cruz 1

Poster Session

Th

1

1

P-Th-341 Optimization of pH-Responsive Hydrogels for Delivery of HMW Proteins S. Horava1 and N. Peppas1 1

University of Ibadan, Ibadan, Nigeria

1

1 The University of North Carolina at Chapel Hill, Chapel Hill, NC, 2North Carolina State University, Raleigh, NC

1

1

Johns Hopkins University, Baltimore, MD

P-Th-38 Development Of A Predictive Maintenance GUI For Medical Linear Accelerators C. Nguyen1,2, C. Able2, A. Baydush2, and M. Munley1,2 Virginia Tech - Wake Forest School of Biomedical Engineering and Sciences, Winston Salem, NC, 2Wake Forest School of Medicine, Winston Salem, NC

1

The University of Texas at Austin, Austin, TX

)

P-Th-342 Ultrasound-triggered Disruption and Self-healing of Reversibly-crosslinked Hydrogels for Drug Delivery and Enhanced Chemotherapy N. Huebsch1,2, C. Kearney1,2, X. Zhao1,2, J. Kim1,2, C. Cezar1,2, Z. Suo1, and D. Mooney1,2 Harvard University, Cambridge, MA, 2Wyss Institute for Biologically Inspired Engineering, Cambridge, MA

1

P-Th-343 Temperature-sensitive Nanoparticles for Lung Cancer Treatment J. Menon1,2, K. Vu1, D. Nguyen1,2, and K. Nguyen1,2 University of Texas at Arlington, Arlington, TX, 2University of Texas Southwestern Medical Center at Dallas, Dallas, TX

1

P-Th-39 ECG Signal Transmission Through GSM Voice Channel S. Dehghanojamahalleh1, B. Pliskow1, and M. Kaya1 Florida Institute of Technology, Melbourne, FL

1

P-Th-344 Modeling the Effect of Oleic Acid Absorption on Bioavailable Griseofulvin Concentration Y. Yeap1 and R. Carrier1

Track: Drug Delivery, New Frontiers and Special Topics

Responsive and Targeted Drug Delivery Chairs: Jeffrey Capadona, Jill Steinbach P-Th-335 pH-Responsive P(IA-co-NVP) Hydrogels for the Oral Delivery of High Isoelectric Point Proteins M. Koetting1, A. Zhang1, and N. Peppas1 1

The University of Texas at Austin, Austin, TX

P-Th-336 Tumor-Targeted Magnetic Nanoparticles for Thermo-Controlled Drug Release J. Caminero1 and M. Domenech1 University of Puerto Rico at Mayaguez, Mayaguez, PR, Puerto Rico

1

1

Northeastern University, Boston, MA

P-Th-345 MMPs-responsive Release of SiRNA from 4-arm PEG-siRNA Conjugate H. Kim1 and H. Yoo1 1

Kangwon National University, Chuncheon, Korea, Republic of

P-Th-346 Single Molecule Mechanics of Peptide-condensed DNA: Dynamic Regulation by pH and Zn2 A. Lee1, A. Karcz1, R. Akman1, T. Zheng1, S. Kwon1, S-T. Chou1, S. Sucayan1, L. Tricoli1, J. Hustedt1, J. Kahn1, A. Mixson2, and J. Seog1 University of Maryland, College Park, MD, 2University of Maryland School of Medicine, Baltimore, MD

1

P-Th-347 Ultrasound-Triggered Noninvasive Regulation of Blood Glucose Levels Using Microgels Integrated with Insulin Nanocapsules J. Di1, Y. Jing2, and Z. Gu1 University of North Carolina at Chapel Hill | North Carolina State University, Raleigh, NC, North Carolina State University, Raleigh, NC

1

)

P-Th-337 Controlled Release of Lipoplexes using Acoustic Droplet Vaporization M. Pilon1, C. Wilson1, D. Jones1, R. Franceschi1, and M. Fabiilli1 1

University of Michigan, Ann Arbor, MI

P-Th-338 pH-Responsive Polymeric Particulate Systems for Micronutrients Fortification of Salt X. Xu1, R. Langer1, and A. Jaklenec1 1

Massachusetts Institute of Technology, Cambridge, MA

P-Th-339 Development of pH-Responsive Hydrogel Carriers for Oral Vaccine Delivery L. Sharpe1, Y. Khairandish1, and N. Peppas1 1

The University of Texas at Austin, Austin, TX

2

P-Th-348 Development of Multi-Functional Core-Shell NPs for Targeted Lung Cancer Dual Therapy J. Menon1, A. Kuriakose1, E. Hernandez2, L. Gandee2, S. Zhang2, M. Takahashi2, Z. Zhang2, D. Saha2, and K. Nguyen1 University of Texas at Arlington, Arlington, TX, 2University of Texas Southwestern Medical Center, Dallas, TX

1

P-Th-349 Developing a Targeted Oral Drug Carrier Using a Layer-by-Layer Chitosan and Alginate Enteric Coating G. Mosley1, S. Cheng1, K. Chen1, and D. Kamei1 UCLA, Los Angeles, CA

1

P-Th-350 Modeling Release Behaviors Of Stimuli-Responsive Polyelectrolyte Multilayer Films J. Min1,2, R. Braatz1, and P. Hammond1,2 MIT, Cambridge, MA, 2Koch Institute of Integrative Cancer Research, Cambridge, MA

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

114

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9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

2014 | october 23 | Thursday

- 10:30am, 3:30pm - 4:30pm

P-Th-351 Development of “Smart” Particles Based on DNA-Crosslinked Hydrogels for Drug Delivery

P-Th-362 Biophysical simulation of targeted nanoparticle adhesion dynamics to optimize delivery

R. Danso1, K. Abdelrahman1, and T. Betancourt1

M. Wang1 and J. Haun1

1

Texas State University, San Marcos, TX

1

UC Irvine, Irvine, CA

P-Th-352 Iron Oxide Nanoparticles-Embedded Polymeric Microgels for Magnetic Responsive Drug Delivery

P-Th-363 A Smart Capsule with GI Tract Location Specific Payload Release

B. Sung1, H. Yan1, S. Shaffer1, C. Kim1, and M-H. Kim1

1

1

Kent State University, Kent, OH

P-Th-353 Enhanced Colorectal Drug Delivery Using Hypotonic Enema Formulations K. Maisel1, T. Moench2, C. Hendrix1, R. Cone1, L. Ensign1, and J. Hanes1 1

Johns Hopkins University, Baltimore, MD, 2ReProtect Inc., Baltimore, MD

W. Yu1, R. Rahimi1, M. Ochoa1, and B. Ziaie1 Purdue University, West Lafayette, IN

P-Th-364 Functionalized Particle Adhesion Depends on Bifurcation Angle G. Lamberti1, A. Smith2, M. Kiani1, B. Prabhakarpandian2, and K. Pant2 1

Temple University, Philadelphia, PA, 2CFD Research Corporation, Huntsville, AL

P-Th-354 Development of a Material Platform for Hypoxia-Targeted Gene Delivery

P-Th-365 Liposome-Conjugated Monoclonal Antibody Lability to Ultraviolet Sterilization Introduced by Lysyl Residue Derivatization

J. Madrigal1, S. Rezvani1, A. Koubeissi2, K. Bouhadir2, and E. Silva1

M. Klegerman1, E. Golunski1, and D. McPherson1

University of California Davis, Davis, CA, 2American University of Beiruit, Beirut, Lebanon

1

P-Th-355 Determining the Specificity of a Multivalent Polymeric Antigen-Specific Immunotherapy for Multiple Sclerosis

P-Th-366 Characterization of the In Vitro Interactions of a Liver Cancer-Specific Aptamer

B. Hartwell1, J. Sestak1, B. Sullivan1, D. Moore1, H. Shinogle1, T. Siahaan1, and C. Berkland1

M. Sutton1, E. Barnes1, S. Mitchell1, T. Betancourt1, and S. Weigum1 1

Th

University of Texas Health Science Center - Houston, Houston, TX

1

University of Kansas, Lawrence, KS

Poster Session

Texas State University, San Marcos, TX

1

P-Th-356 Genipin Releasing Suture Coatings For Reducing The Occurrence Of Suture Pull-Out Through Damaged Connective Tissue S. Sundararaj1, P. Slusarewicz 1, and T. Hedman1,2

P-Th-367 Magnetic Field-enhanced Cell Uptake of Doxorubicin-loaded Magnetic Nanoparticles for Tumor Treatment I. Venugopal1, S. Pernal1, H. Engelhard2, and A. Linninger1 University of Illinois at Chicago, Chicago, IL, 2University of Illinois College of Medicine at Chicago, Chicago, IL

1

Orthopeutics L.P., Lexington, KY, 2University of Kentucky, Lexington, KY

1

P-Th-357 Targeting Metastatic Prostate Cancer Using Engineered Ligands K. Mayle1, R. Chiu1, S. Wang1, K. Dern1, A. Wu1, A. Mason2, and D. Kamei1

P-Th-368 Electrokinetically Assisted Targeted Drug Delivery System For In-vitro Drug-cell Interaction Studies

University of California Los Angeles, Los Angeles, CA, 2University of Vermont, Burlington, VT

R. Taruvai Kalyana Kumar1, A. Wangzhou1, D. Kinnamon1, and S. Prasad1

P-Th-358 Targeted Liposomes Containing Superoxide Dismutase and Fasudil Reduces Chronic Symptoms in PAH Rats

P-Th-369 Controlled Dual Release of Dexamethasone Sodium Phosphate and Dexamethasone from Electrospun Membranes for Prevention of Peritoneal Adhesion

1

N. Gupta1, C. Woods2, E. Nozik-Grayck2, and F. Ahsan1 Texas Tech University Health Sciences Center, Amarillo, TX, 2University of Colorado Denver, Aurora, CO

1

P-Th-359 Nanoparticle-mediated Therapies for Pediatric Brain Diseases E. Nance1, F. Zhang1, M. Mishra1, S. Pramodh-Kamb hamp ati1, K. Rangaramanujam1, and S. Kannan1 Johns Hopkins University, Baltimore, MD

1

P-Th-360 EGF-Conjugated Dendrimers For Local, Sustained And Targeted Delivery Of Chemotherapeutic Drugs For Treatment Of Breast Cancer N. Oliva-Jorge1, E. Edelman1,2, and N. Artzi1,2 MIT, Cambridge, MA, 2Brigham and Women's Hospital, Harvard Medical School, Boston, MA

1

P-Th-361 Evaluating Effects Of Convection And Diffusion On A Gadolinium Tracer In Convection-Enhanced Delivery J. Foo1, C. Schaffer1, and W. Olbricht1 Cornell University, Ithaca, NY

1

1

University of Texas at Dallas, Richardson, TX

C. Ma1, C. Xiong2, and X. Liu1 Baylor College of Dentistry, Dallas, TX, 2University of Chinese Academy of Sciences, Chengdu, China, People's Republic of

1

Track: Nano to Micro Technologies, Biomaterials

BioMEMS, Tissue and Organs on a Chip, Cell Behavior in Micro/Nano Devices, Paperfluidics Chairs: Maribel Vazquez, Lance Kam P-Th-530 Use of Physiologically-Based in vitro Models of the Gastrointestinal Tract to Study TiO2 and SiO2 Nanoparticle Interactions with Mineral Absorption Z. Guo1, E. Tako2, and G. Mahler3

Binghamton University, Binghamton, NY, 2Plant, Soil and Nutrition Laborator, Agricultural Research Services, U.S. Department of Agriculture, Ithaca, NY, Ithaca, NY, 3Binghamton Univsersity, Binghamton, NY

1

See page 92 for Poster floor plan

BMES 2014

115

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-531 Development of a Perfusable 3D Tumor Platform to Study Nanoparticle Transport

P-Th-542 An Arrayed Microfluidic Hanging Drop System for EB Formation and Culture

M. DeWitt1, R. Newsome2, A. Pekkanen1, and N. Rylander1,2

H-W. Wu1 and H. Chia-hsien1

1

Virginia Tech-Wake Forest, Blacksburg, VA, 2Virginia Tech, Blacksburg, VA

P-Th-543 The Effect of Fluid Perfusion on Human Umbilical Vein Endothethial Cell Tube Formation

K. Yang1, H-J. Park1, J. Kim1, S. Han2, S. Chung2, and S-W. Cho1

C. Chan1, V. Goral2, P. Yuen2, and T. Huang1

Department of Biotechnology, Yonsei University, Seoul, Korea, Republic of, 2School of Mechanical Engineering, Korea University, Seoul, Korea, Republic of

1

P-Th-533 Development of a Novel, Physiologically and Anatomically Realistic in vitro Pediatric Blood Brain Barrier on a Chip

Th

National Health Research Institutes, Miaoli County, Taiwan

P-Th-532 3D Microfluidic Device to Study the Neurotrophic Effect of Mesenchymal Stem Cells for Enhanced Human Neural Stem Cell Differentiation 1

Poster Session

1

S. Deosarkar1, B. Augeli1, P. Pandian2, B. Krynska1, and M. Kiani1 1

Temple University, Philadelphia, PA, 2CFD Research Corporation, Huntsville, AL

P-Th-534 Gelatin Electrospun Nanofibrous Composite for use in Organ-on-a-chip Microfluidics A. Nicolini1 and J-Y. Yoon1 1

The University of Arizona, Tucson, AZ

P-Th-535 A Novel In Vitro Blood Brain Barrier Platform for Preliminary Drug Studies C. Hovell1, G. Barabino2, L. Taite1, and Y. Kim1 Georgia Institute of Technology, Atlanta, GA, 2City College of New York, New York, NY

Pennsylvania State University, University Park, PA, 2Corning Incorporated, Corning, NY

P-Th-544 A Microfluidic Device to Model Active and Passive Transport Functions of the Human Kidney C. Sakolish1, J. Cohen1, M. Reiss1, and G. Mahler1 1

Binghamton University, Binghamton, NY

P-Th-545 Do Substrate Cleaning Methods Affect Cellular Response? B. Kirkland1, K. Hafner1, M. Kennedy1, and D. Dean1 1

Clemson University, Clemson, SC

P-Th-546 Microstructured Multi-Well Plate for Three-Dimensional Packed Cell Seeding and Culture V. Goral1, S. Au2, R. Faris1, and P. Yuen1 1

Corning Incorporated, Corning, NY, 2Massachusetts General Hospital, Charlestown, MA

1

)

P-Th-536 Biomimetic Modifications to Microfluidic Silk Spinning D. Li1, D. Backman1, M. Jacobsen1, N. Rim1, D. Kaplan2, and J. Wong1 1

Boston University, Boston, MA, 2Tufts University, Medford, MA

)

P-Th-537 Three-Compartment Microfluidic Device For Generating Heterogeneous Shear Stress Pattern X. Zhang1 and Y. Zhao1 1

Ohio State University, Columbus, OH

P-Th-538 BioMEMS Device Intergrated With CNxCNT Membrane For Blood Plasma Extraction Y-T. Yeh1, N. Perea-Lopez1, M. Terrones1, and S. Zheng1 1

The Pennsylvania State University, University Park, PA

P-Th-539 Development of a Cell-Based Model of the Ocular Fundus within a Microfluidic Device H. Kaji1, S. Ito1, K. Nagamine1, M. Nishizawa1, N. Nagai1, and T. Abe1 1

Tohoku University, Sendai, Japan

P-Th-540 Human Induced Pluripotent Stem Cell Derived 3D Cardiac Tissue Model for Drug Screening A. Mathur1, P. Loskill1, K. Shao1, S. Hong1, N. Marks1, L. Lee1, B. Conklin2, and K. Healy1 University of California, Berkeley, Berkeley, CA, 2University of California, San Francisco, San Francisco, CA

1

P-Th-541 Study of Renal Function in a Kidney-on-a-chip with Curved Geometry S. Yu1, Y. Kim1, J. Park1, W. Lee-Kwon1, Y-K. Cho1 and J. Kim1 1

Ulsan National Institute of Sicence and Technology, Ulsan, Korea, Republic of

P-Th-547 Detection of Neural Responses Using The In Vitro Chip-Based Human Investigational Platform (iCHIP) H. Enright1, E. Mukerjee1, N. Fischer1, S. Felix1, W. McNerney1, J. Osburn1, F. Qian1, A. Chang1, S. Baker1, E. Wheeler1, K. Kulp1, J. Zhang2, G. Page2, P. Miller2, A. Ghetti2, and S. Pannu1 1

Lawrence Livermore National Lab, Livermore, CA, 2Anabios, Inc, San Diego, CA

P-Th-548 Engineering Microchip Modules for Monitoring Vascular Permeability Y. Sei1 and Y. Kim1 1

Georgia Institute of Technology, Atlanta, GA

P-Th-549 Monolithic Droplet Generator and Microarray for Screening Islet Beta Cells Z. Zhao1, R. Liu1, D. Hu1, and J. Lo1 1

University of Michigan-Dearborn, dearborn, MI

P-Th-550 Microengineered Biomimetic Liver Sinusoids-on-a-Chip for Drug Toxicity Studies Y. Kim1 and Y-K. Cho 1 1

Ulsan National Institute of Science and Technology, Ulsan, Korea, Republic of

P-Th-551 Quantitative Analysis of CCL19-induced Chemotaxis of Human Dendritic Cells in 3D Microenvironment H. Hwang1, C. Shin1, J. Park1, Y. Do1, and Y-K. Cho1 1

Ulsan National Institute of Science and Technology, Ulsan, Korea, Republic of

P-Th-552 Metabolism-Induced Toxicity Screening on a Micropillar/Microwell Chip Platform Using THLE-2 Cells Expressing Combinations of Drug Metabolizing Enzymes S. Kwon1, D. Lee2, B. Ku2, D. Clark3, J. Dordick1, and M-Y. Lee4 1 Rensselaer Polytechnic Institute, Troy, NY, 2Samsung Electro-Mechanics Co, Suwon, Korea, Republic of, 3University of California at Berkeley, Berkeley, CA, 4Cleveland State University, Cleveland, OH

P-Th-553 A Microfluidic System to Study the Effects of Mechanically Loaded Osteocytes on Osteoclastogenesis and Recruitment P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

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BMES 2014

K. Middleton1 and L. You1 1

University of Toronto, Toronto, ON, Canada

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

P-Th-554 Chemotactic Gradients to Induce Photoreceptor Transplantation S. Mishra1, J. Unachukwu2, S. Redenti2, and M. Vazquez1 1 City College of New York, New York, NY, 2The Graduate School and University Center, City University of New York, New York, NY

P-Th-555 Modeling Spiral Oxygen Gradient for Simultaneous Hypoxic Stimulation and Cell Respiration Monitoring M. Zhou1, K. Milliman1, Z. Zhao1, M. Wang1, J. Lo1, and N. Chakraborty1 1

T. Khire1, L. Salas Estrada1, R. Waugh1, and J. McGrath1 1

Columbia University, New York, NY, 2The University of Oxford, Oxford, United Kingdom

P-Th-558 A Microfluidic Oxygen Landscape Device Demonstrates Modulation of Hypoxic Signaling via Crosstalk between Normoxic and Hypoxic Endothelial Cells M. Rexius1, D. Eddington1, and J. Rehman1 University of Illinois at Chicago, Chicago, IL

Virginia Tech, Blacksburg, VA, 2Virginia Bioinformatics Institute, Blacksburg, VA

P-Th-560 Rapid Bacteria Capture In Capillary-driven Microfluidic Device A. Olanrewaju1 and D. Juncker1 McGill University, Montreal, QC, Canada

1

University of California, Riverside, Riverside, CA

)

P-Th-568 Modeling Drug Clearance and Drug-Drug Interactions in Long-Term Engineered Human Liver Cultures C. Lin1, J. Shi2, A. Moore2, and S. Khetani1

1 Academia Sinica, Taipei, Taiwan, 2University of Virginia, Charlottesville, VA, 3Oregon State University, Corvallis, OR, 4National Yang-Ming University, Taipei, Taiwan

Track: Neural Engineering, Device Technologies and Biomedical Robotics

Neural Engineering I: BCI, Devices, and Rehab Chairs: Lisa Flanagan, Jaydip Desai

)

P-Th-80 Non-invasive Brain-Computer Interface for Prosthetic Control 1

Stevens Institute of Technology, Hoboken, NJ

P-Th-81 Chronic CNS Recording Studies in an Aged Rat Model M. Christensen1, N. Nolta1, and P. Tresco1 1

University of Utah, Salt Lake City, UT

P-Th-82 Investigation of the Neuroinflammatory Response to Antioxidant-Releasing Mechanically-Compliant Implants

Carnegie Mellon University, Pittsburgh, PA

T. Liang , G. Fridley , P. Yager , and E. Fu ,

1 2

University of Washington, Seattle, WA, 2Oregon State University, Corvallis, OR

P-Th-565 Nonplanar Three-Dimensional Paper Microfluidic Circuits Constructed with Patterned Adhesive B. Kalish1 and H. Tsutsui1 University of California, Riverside, Riverside, CA

J. McBride1, X. Zhao1, N. Munro2, G. Jicha3, F. Schmitt3, R. Kryscio3, C. Smith3, and Y. Jiang3 1

University of Tennessee, Knoxville, TN, 2Oak Ridge National Laboratory, Oak Ridge, TN, University of Kentucky, Lexington, KY

A. Copeman1 and B. Campbell1

P-Th-564 Investigation of the Format-dependent Spatial Distribution of Binding in a Malaria Antigen Assay; Implications for Higher-sensitivity Detection 1

P-Th-83 Detection of Early Alzheimers Disease Using Nonlinear State Space Reconstruction of EEG

P-Th-84 Exploring Differences in Concentration Levels While Playing Games

B. Holt1, M. Islam1, and K. Dahl1

1

Poster Session

3

P-Th-563 Single Wall Carbon Nanotube Interactions with F-actin

1

Colorado State University, Fort Collins, CO, 2Hepregen Corporation, Medford, MA

Case Western Reserve University, Cleveland, OH, 2Louis Stokes Cleveland VA Medical Center, Cleveland, OH, 3University of Fribourg, Marly, Switzerland

Y-H. Su1,2, P-C. Chiang1, L-J. Cheng1,3, C-H. Lee1,4, N. Swami2, and C-F. Chou1

1

C. Castro1, C. Rosillo1, and H. Tsutsui1

1

P-Th-562 Optimizing the Aspect Ratio of PLGA Nano-grooves for Controlling Cell Division Axis and Migration

1

P-Th-567 Predicting Wicking in Wax-bound Paper Microfluidic Channels

J. Nguyen1,2, K. Buchanan1,2, M. Jorfi3, E. Foster3, C. Weder3, and J. Capadona1,2

P-Th-561 cancelled by author

1

Boston University, Boston, MA

T. Callahan , A. Ritter1, and T. Sigler1

D. Loufakis1, Z. Cao1, S. Ma1, D. Mittelman1,2, and C. Lu1

1

1

1

P-Th-559 Unidirectional Electrical Pulses For Cell Alignment In A Closed Microfluidic Chamber 1

S. Wong1, M. Cabodi1, and C. Klapperich1

1

J. Lee1, M. Dustin2, and L. Kam1

1

P-Th-566 Concentrating a Urinary Tuberculosis Biomarker by Heated Evaporation on a Paper Microfluidic Device

University of Rochester, Rochester, NY

P-Th-557 Single Cell, High Efficiency Analysis of Rare T cell Response using a Magnetic Sieving Device 1

- 10:30am, 3:30pm - 4:30pm

The University of Michigan-Dearborn, Dearborn, MI

P-Th-556 Microvasculature Mimetic Device to Model Physiological Barrier Properties in Sepsis

2014 | october 23 | Thursday

1

Robert Morris University, Moon Township, PA

P-Th-85 Open Vs. Closed Loop EEG-Based Control Using Binaural Stimulation C. Beauchene1 and A. Leonessa1 1

Virginia Tech, Blacksburg, VA

P-Th-86 Peripheral Sensory Feedback to Improve Gait with a Feline Hindlimb Prosthesis H. Park1, B. Prilutsky1, and S. DeWeerth1 1

Georgia Institute of Technology, Atlanta, GA

See page 92 for Poster floor plan

BMES 2014

117

Th

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-87 Stability and Sub-chronic Biocompatibility of Carbon Nanotube Fiber Microelectrodes

P-Th-99 Understanding Synchrony in Networks of Neurons that are NoiseDominated

F. Vitale1, S. Summerson1, B. Aazhang1, C. Kemere1, and M. Pasquali1

J. Bauer1, F. Fernandez1, and J. White1

1

Th

1

University of Utah, Salt Lake City, UT

P-Th-88 neuroPG: Open Source Software For Optical Pattern Generation And Data Acquisition

P-Th-100 Mental Activation of a Light Bulb Using Inexpensive Neural Interface Technology

B. Avants1, D. Murphy1, J. Robinson1, and J. Dapello2

J. Leipheimer1, D. Cesario1, L. Zearing1, and B. Campbell1

1

Poster Session

Rice University, Houston, TX

Rice University, Houston, TX, 2Hampshire College, Amherst, MA

1

Robert Morris University, Moon Township, PA

P-Th-89 A Study on NMDA Dose-Response Effect on Chick Forebrain Neuron Culture on an MEA

P-Th-101 Nonlinear Method to Assess Autonomic Function in Diabetic patients Type 2

X. Yang1, S. Kuang1, and B. Gao1

1

1

Clemson University, Clemson, SC

P-Th-90 Development of Electrical Switch System for Desynchronizing Abnormal Neural Activity D. Kim1, H. Jung1, and Y. Nam1 1

N. Hong1, S. Joo1, and Y. Nam1

K. O'Neill1, G. Mattson1, T. Shinbrot1, and B. Firestein1 Rutgers University, Piscataway, NJ

P-Th-103 Modelling Gait Syndrome in Huntington’s disease: the Genetic Algorithm Approach O. Ajibola1, F. Ogunwolu1, O. Ibidapo-Obe1, V. Olunloyo1, and A. Osuntoki1 1

KAIST, Daejeon, Korea, Republic of

Tennessee Tech University, Cookeville, TN

P-Th-102 Learned Stimulus Response in Experimental and Simulated Neural Networks 1

KAIST, Daejeon, Korea, Republic of

P-Th-91 Novel Micropatterns on a Microelectrode Array Using Agarose Hydrogel for Neural Network Design 1

A. Kamal1

University of Lagos, Lagos, Nigeria

P-Th-92 Fabrication and Evaluation of Brain Drug Delivery Microdevices

P-Th-104 Effect Of Transcranial Direct Current Stimulation On Behavior Impairments Following Neonatal HIE Stroke

J. Sy1, K. Spencer1, R. Langer1, and M. Cima1

C. Anderson1, T. DeMarse1, P. Carney1, M. Weiss1, and M. Douglas-Escobar1

1

Massachusetts Institute of Technology, Cambridge, MA

1

P-Th-93 Reinforcement of Platinum Black Structure Through Polydopamine Incorporation

E. Meyers1, A. Sindhurakar2, S. Hays1, A. Sloan1, M. Kilgard1, J. Carmel2, and R. Rennaker1

R. Kim1 and Y. Nam1 1

University of Texas at Dallas, Richardson, TX, 2Burke-Cornell Medical Research Institute, White Plains, NY

1

KAIST, Daejeon, Korea, Republic of

P-Th-94 Simply Fabricated Protruding Microelectrode Array using Liquid Crystal Polymer (LCP) J. Jeong1, C. Kim1, S. Ahn1, G. Kim1, T. Gwon1, J. Seo1, and S. Kim1 1

H. Lee1, J. Gaire1, M. McDermott1, J. Zhang1, K. Otto1, and K. Otto1 Purdue University, West Lafayette, IN

P-Th-97 A Quantitative Tool For Identifying The Epileptogenic Zone Using Network Connectivity Analysis J. Gurisko , R. Bossemeyer , S. Rhodes , P. Fishback , and K. Elisevich 1

1

1

2

3

Grand Valley State University, Grand Rapids, MI, 2Grand Valley State University, Allendale, MI, 3Spectrum Health System, Grand Rapids, MI

1

P-Th-98 Nonlinear Identification of Functional Spike-Timing-Dependent Plasticity from Simulated Spiking Activity B. Robinson1, D. Song1, and T. Berger1 1

University of Southern California, Los Angeles, CA

P-Th-106 EMG Measurement of Middle Ear Muscle Reflex in Chinchillas Z. Yokell1, D. Nakmali1, S. Jiang1, X. Guan1, and R. Gan1 1

Seoul National University, Seoul, Korea, Republic of

P-Th-95 Improving the Performance of Intracortical Microelectrodes via Structural Modifications and Biochemical Intervention Strategies 1

University of Florida, Gainesville, FL

P-Th-105 Novel Supination Assessment Task In A Rat Model Of Ischemic Stroke

University of Oklahoma, Norman, OK

P-Th-107 Characterization Of Neuropathic Pain In Amputation Neuroma Model R. Granja-Vazquez1, B. Johnston1, M. Le2, S. Trinh2, and M. Romero-Ortega1 1

UT Arlington & UT Southwestern Medical Center, Arlington, TX, 2UT Arlington, Arlington, TX

P-Th-108 A Novel Substrate for In Vitro Optogenetics Experiments A. Hammack1, A. Avendano-Bolivar1, H. Jia1, and B. Gnade1 1

University of Texas at Dallas, Richardson, TX

P-Th-109 Electrostimulation with Subnanosecond Pulses S. Xiao1, A. Pakhomov1, I. Semenov1, D. Kang 1, S. Polisetty1, and K. Schoenbach1 1

Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA

P-Th-110 Development Of An Implantable System For Controlling Rat Eye Pressure S. Bello1, C. Passaglia1, X. Tang1, and S. Malavade1 1

University of South Florida, Tampa, FL

P-Th-111 Transcranial Direct Current Stimulation to Enhance Motor Learning in Healthy Subjects P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

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BMES 2014

P. Oldani1, C. Hogan1, S. Sharma1, S. Michalovic1, and R. Ohrbach1 1

University at Buffalo, Buffalo, NY

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

2014 | october 23 | Thursday

- 10:30am, 3:30pm - 4:30pm

P-Th-112 Low Stress Sleep Deprivation Using Vibration Table Method

P-Th-510 Three Dimensions of Measurements for Global Health Diagnostics

F. Decuir1

M. Script1

1

Louisiana Tech University, Ruston, LA

1

Inspire Living, Inc., Fairfax Station, VA

P-Th-113 High-throughput Mapping of Brain-wide Activities In Awake and Drugresponsive Vertebrates

P-Th-511 3D Printed Fluorometer For Global Health

X. Lin1, S. Wang1, X. Yu1, and P. Shi1

1

1

City University of Hong Kong, Kowloon, Hong Kong

Track: New Frontiers and Special Topics, Translational Biomedical Engineering

Global Health Chairs: TBD P-Th-501 Normalizing Smart Phone Detection of Flourescence for Global Health V. Barker1, M. Lipowicz1, C. Smith1, A. Moskowitz1, C. Van Bussum1, and A. Garcia1 1

Arizona State University, Tempe, AZ

P-Th-502 Assessing the Feasibility of Local Production of Medical Devices in SubSaharan Africa J. Abbas1, M. Poluta2, A. Sabet Sarvestani3, and A. Velazquez-Berumen4 Arizona State Unviersity, Tempe, AZ, 2University of Cape Town, Rondebosch, South Africa, 3 University of Michigan, Ann Arbor, MI, 4World Health Organization, Geneve, Switzerland 1

P-Th-503 Defining Head-Tilt Position for Neonatal and Infant Resuscitation M. Hemani1, B. Gu1, B. Kim1, A. Cruz1, T. Lam1, and U. Bhalala2 1

Johns Hopkins University, Baltimore, MD, 2Johns Hopkins Hospital, Baltimore, MD

M. Lipowicz1 and A. Garcia1 Arizona State University, Tempe, AZ

P-Th-512 Paper-based Diagnostic Devices for Measuring the Level of Organophosphate Poisoning in Human Serum of Patients K-H. Chen1, S-T. Fan1, T-H. Yen2, Y-F. Huang1, and C-M. Cheng1 1 National Tsing Hua University, Hsinchu, Taiwan, 2Chang Gung University and School of Medicine, Taoyuan, Taiwan

Smart Materials/Emerging Tech Chairs: James Abbas, Anand Ramasubramanian

)

P-Th-513 MG63 Morphology and Behavior on Shape-Memory Polymer for Osteoblast Differentiation E. Hewett1, K. Smith2, K. Gall1, Z. Schwartz3,4, and B. Boyan1,3 Georgia Institute of Technology, Atlanta, GA, 2MedShape Solutions, Inc., Atlanta, GA, Virginia Commonwealth University, Richmond, VA, 4University of Texas Health Science Center, San Antonio, TX

1 3

)

P-Th-514 Engineering in Vitro Models to Elucidate the Effect of Microcavitation in Astrocytes S. Sun1, D. Kang2, S. Xiao2, and M. Cho1

N. Adams , K. Davis , D. Wright , and F. Haselton

P-Th-515 A Compact Acoustic Tweezers System for Cell Trapping and In Vivo Applications

1

1

1

1

Vanderbilt University, Nashville, TN

P-Th-505 Paper-Based Diagnostic Accelerates Phase Separation of a Micellar Aqueous Two-Phase System D. Pereira , R. Chiu , A. Thach , and D. Kamei 1

1

1

1

1

UCLA, Los Angeles, CA

Th

Track: New Frontiers and Special Topics, Biomaterials

P-Th-504 Magnetic Bead-Based Enhancement of Rapid Diagnostic Tests 1

Poster Session

1

University of Illinois at Chicago, Chicago, IL, 2Old Dominion University, Norfolk, VA

Y. Li1, K. Lee1, B. Zhu2, Y. Li1, and K. Shung1 NIH Ultrasonic Transducer Resource Center and Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, 2School of Optical and Electronic Information, Huazhong University of Science and Technology, Wuhan, China, People's Republic of 1

P-Th-506 Uterine Contraction Monitoring: Improving Labor Management in Low Resource Settings

P-Th-516 A Novel and Highly Efficient Method for Intracellular Delivery and Accumulation of Trehalose

M. Lamberti1, M. Babb1, and J. Hunt1

A. Abazari1, L. Meimetis1, D. Moore2, S. Hand2, R. Weissleder1, and M. Toner1

1

P-Th-507 Understanding the Design Constraints of the Tanzanian Health Care System J. Kohn1, M. McCorry1, and L. Bonassar1 1

Cornell University, Ithaca, NY

P-Th-508 Independent Dielectrophoretic Monitoring of Clostridium difficile Strains on a Microfluidic Device Y-H. Su1, C. Warren1, R. Guerrant1, and N. Swami1 1

Massachusetts General Hospital - Harvard Medical School, Boston, MA, 2Louisiana State University, Baton Rouge, LA

1

Johns Hopkins University, Baltimore, MD

University of Virginia, Charlottesville, VA

P-Th-509 Polymer-coated Gold Nanoprobes For The Concentration And Detection Of Protein Biomarkers For Resource-poor Settings R. Chiu1, P. Nguyen1, J. Wang1, E. Jue1, A. Thach1, B. Wu1, and D. Kamei1

P-Th-517 nBioChip (nano-Biofilm Chip) - A Platform for Ultra-high-throughput Drug Discovery of Antimicrobial Drugs Against Polymicrobial Biofilms A. Srinivasan1,2, K. Leung3, J. Lopez-Ribot1,2, and A. Ramasubramanian1,2 The University of Texas at San Antonio, San Antonio, TX, 2South Texas Center for Emerging Infectious Diseases, San Antonio, TX, 3US Army Institute of Surgical Research, FortSam Houston, TX

1

P-Th-518 CFD-Guided Experimental Investigation of Corneal Biomechanics in Microgravity D. Sathyanarayan1, N. Do2, G. Girish2, J. Grewal2, R. Kowalchuk1, N. Quintero2, G. Truskey1, S. Gangadharan2, B. Dikici2, and E. Divo2 1

Duke University, Durham, NC, 2Embry-Riddle Aeronautical University, Daytona Beach, FL

University of California, Los Angeles, Los Angeles, CA

1

See page 92 for Poster floor plan

BMES 2014

119

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-519 The Role of Skin Dendritic Cells in Nanoparticle Transport in SKH-1 Hairless Mice S. Jatana1 and L. DeLouise1 1

University of Rochester, Rochester, NY

P-Th-520 Lignocellulosic-based Analytical Devices

Biomechanics and Rehabilitation of the Upper Limb

C-M. Kuan 1 and C-M. Cheng1

Chairs: Wendy Murray, Katherine Saul

1

NanoEngineering and MicroSystems, Hsinchu, Taiwan

P-Th-521 Neurostimulation of the Cholinergic Anti-Inflammatory Pathway Reduces Endoscopy Score in Rat Colitis Y. Levine1, K. Black1,2, and M. Faltys1 1

Poster Session

Th

Track: Orthopaedic and Rehabilitation Engineering, Biomechanics

SetPoint Medical Corporation, Valencia, CA, 2Ra Pharmaceuticals, Cambridge, MA

P-Th-522 Creating a Geometrically Distinct Human Body FEM Using Radial Basis Function Interpolation

P-Th-156 Gestural Navigation of Virtual Exercise Environments for People with Mobility Impairments S. Pool1, L. Malone2, J. Rimmer1, and A. Eberhardt1 University of Alabama at Birmingham, Birmingham, AL, 2Lakeshore Foundation, Birmingham, AL

1

P-Th-157 Robotics Based Human Body Model for Improvement of Upper Extremity Prostheses

N. Vavalle1,2, S. Schoell1,2, A. Weaver1,2, J. Stitzel1,2, and F. Gayzik1,2

D. Menychtas1, D. Lura2, S. Carey1, and R. Dubey1

1

Wake Forest School of Medicine, Winston-Salem, NC, 2Wake Forest Center for Injury Biomechanics, Winston-Salem, NC

1

P-Th-523 Biohybrid Soft Robotics Flagellum Enables Free Swimming

P-Th-158 Development of Prosthetic Fingertips for Improved Touch Screen Interactions

B. Williams1, J. Rajagopalan2, and T. Saif1

J. Heasley1, A. Azanaw1, K. Slis1, D. Kiska1, and B. Campbell1

1

University of Illinois at Urbana-Champaign, Urbana, IL, 2Arizona State University, Tempe, AZ

P-Th-524 Coordination of Ventilatory Mechanisms in the Madagascar Hissing Cockroach and Potential Bio-Inspired Microfluidic Systems J. Garrett1 and J. Socha1 1

Virginia Tech, Blacksburg, VA

1

University of South Florida, Tampa, FL, 2Florida Gulf Coast University, Fort Mayers, FL

Robert Morris University, Moon, PA

)

P-Th-159 Functional Task Analysis for Human-Machine Performance Limits R. Patterson1, J. Stanford2, C. Young1, D. Popa2, and N. Bugnariu1 University of North Texas Health Science Center, Fort Worth, TX, 2University of Texas at Arlington, Arlington, TX

1

P-Th-525 What Happens When Pupae Pump? Internal Effects of Abdominal Pumping in the Beetle Zophobas morio

P-Th-160 Mathematical simulation of multi-insertion site tendon transfer surgery for lateral pinch throughout thumb flexion-extension plane

M. Kenny1, H. Pendar1, and J. Socha1

S. O'leary1, N. Salyapongse1, D. Thelen1, and J. Towles1

1

Virginia Tech, Blacksburg, VA

1

University of Wisconsin-Madison, Madison, WI

P-Th-526 Development and Characterization of Antibodies to Nanoparticles to Enhance their Detection in Human Skin

P-Th-161 Target Postures for Maximum Voluntary Contraction of Extrinsic Thumb Muscles During Intramuscular EMG

S. Ravichandran1, M. Sullivan1, and L. DeLouise1

M. de Bruin1,2, S. Wohlman2, and W. Murray1,2

1

University of Rochester, Rochester, NY

1

Rehabilitation Institute of Chicago, Chicago, IL, 2Northwestern University, Chicago, IL

P-Th-527 Little Joey - Development of a Personalized Toy to Improve Cognitive, Sensory, and Motor Skills in a Neurologically Disabled Child

P-Th-162 Elbow Stiffness at High Torque Levels

N. Ahmed1, J. Sellman1, L. Bray1, and N. Peixoto1

1

1

George Mason University, Fairfax, VA

D. Ludvig1,2, H. Lee1, and E. Perreault1,2 Rehabilitation Institute of Chicago, Chicago, IL, 2Northwestern University, Chicago, IL

P-Th-528 3D Printed Glass for the Correction of Eye Defects

P-Th-163 Biomechanical Simulation Of Pinch Forces From Experimental Muscle Activations

S. perumal1

S. Wohlman1 and W. Murray1

1

University of South Florida, tampa, FL

1

Northwestern University, Chicago, IL

P-Th-529 A Battery-less Pressure Driven Smart Pill for Oral to Systemic Protein Delivery

P-Th-164 Design of a 3-D Printed Exoskeleton Glove to Passively Move a Paralyzed Hand

K. aran1, J. Paredes1, K. Lee1, A. Acharya1, D. Liepmann1, and N. Murthy1

E. Austin, Jr.1, Y-H. Shin1, W. Wang1, and J-W. Choi1

1

University of California, Berkeley, CA

1

Louisiana State University, Baton Rouge, LA

P-Th-165 Design and Development of a 3D Printed Dexterous Prosthetic Hand P. Murugesu1 and Y. M. Al-Smadi1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

120

BMES 2014

Texas A&M University Kingsville, TX

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

2014 | october 23 | Thursday

- 10:30am, 3:30pm - 4:30pm

P-Th-166 Modeling Influence of Whole Body Vibration on Upper Extremity Neuromuscular Performance During Space Vehicle Launch

P-Th-132 The Effect of IL-1Beta on Axonal Growth Potential Induced by Interplay Between Annulus Fibrosus and DRG Neurons

T. Deleon-Nwaha1 and D. Peterson1

H. Kim1, T. Caspar1, S. Shah2, and A. Hsieh1,3

1

University of Connecticut Health Center, Farmington, CT

1 3

P-Th-167 Preventing Hand-Arm Vibration Injuries by Selecting Gloves Based on ToolSpecific Vibrations T. Asaki1, S. Kudernatsch1, and D. Peterson1 1

P-Th-133 Effects of Membrane Cholesterol Enrichment on Osteoblast Responsiveness to Hydrodynamic Pressures K. Lough1 and H. Shin1

University of Connecticut Health Center, Farmington, CT

1

Track: Orthopaedic and Rehabilitation Engineering, Cellular and Molecular Bioengineering

Mechanobiology, Tissue Engineering and Regenerative Medicine, Musculoskeletal Pain Chairs: Lijie Grace Zhang, Kyle Allen P-Th-125 Tunable Low Intensity Pulsed Ultrasound for Improving Stem Cell Functions in 3D Printed Scaffolds C. O'Brien1, M. Aliabouzar1, K. Sarkar1, and L. Zhang1 The George Washington University, Washington, DC

University of Kentucky, Lexington, KY

)

P-Th-134 Mechanical Stimulation of a Healing Fracture in Mice Using An External Fixator J. Currey1, M. Mancuso1, and S. Kalikoff1 1

1

University of Maryland, College Park, MD, 2University of California-San Diego, La Jolla, CA, University of Maryland, Baltimore, MD

Poster Session

Union College, Schenectady, NY

Th

Track: Orthopaedic and Rehabilitation Engineering, Biomechanics

Musculoskeletal Imaging Chairs: Wendy Murray, Katherine Saul P-Th-617 Regional Characterization of Effective Joint Space & Hip-joint Capsule Volume from Magnetic Resonance Imaging

P-Th-126 Comparing Cyclic Tensile Properties of Native and Decellularized Porcine Knee Meniscus

P. Menon1, P. Albal1, B. Mosier2, L. Maynard2, and J. Christoforetti2

E. Lakes1, M. Diaz1, P. McFetridge1, and K. Allen1

P-Th-618 The Effect of Skin Motion on Dynamic Musculoskeletal Ultrasound

1

University of Florida, Gainesville, FL

P-Th-127 Multi-approach Assessments of BMSCs Transplantation After Nerve Crush Injury S. Liu1, H. Cai1, A. Hoke1, and X. Jia1,2 Johns Hopkins University School of Medicine, Baltimore, MD, 2University of Maryland School of Medicine, Baltimore, MD

1

P-Th-128 Anisotropy Promotes Myogenic Differentiation Via Integrins M. McClure1,2, R. Olivares-Navarrete2, Z. Schwartz2, and B. Boyan2 Hunter Holmes Veterans Affairs Medical Center, Richmond, VA, 2Virginia Commonwealth University, Richmond, VA

1

P-Th-129 Does Collagen Crosslinking in Ageing and Diabetes Modulate Overload Damage to Tendon Collagen? A. Brown1, S. Veres1,2, and J. Lee1 1

D. Lipps1, S. Lee1, B. Wang1, and E. Perreault1 1

Northwestern University, Chicago, IL

P-Th-619 Contrast Enhanced Computed Tomographic Analysis of the Biochemical and Biomechanical Properties of Human Articular Cartilage: Cationic vs. Anionic Contrast R. Stewart1,2, B. Cooper1, B. Lakin1,2, J. Freedman1,2, M. Grinstaff1, and B. Snyder2 1

Boston University, Boston, MA, 2Beth Israel Deaconess Medical Center, Boston, MA

P-Th-620 Accuracy and Feasibility of Dual Fluoroscopy: In-Vivo Kinematics of Tibiotalar and Subtalar Joints K. Roach1, B. Wang1, A. Kapron1, N. Fiorentino1, M. Singer1, C. Saltzman1, and A. Anderson1 1

University of Utah, Salt Lake City, UT

Dalhousie University, Halifax, NS, Canada, 2Saint Mary's University, Halifax, NS, Canada

P-Th-130 Use of a Novel Behavioral Device to Measure Orofacial Mechanical Allodynia in Rats E. Rohrs1, K. Kapernaros1, A. Jenkins1, J. Neubert1, and K. Allen1 1

Sun Yat-sen University - Carnegie Mellon University Joint Institute of Engineering, Pittsburgh, PA, 2Allegheny Health Network, Pittsburgh, PA

1

University of Florida, Gainesville, FL

P-Th-131 Low-intensity Vibration Amplifies Beneficial Effects of Sleeve Gastrectomy on Bone Marrow Niche A. Yang1, G. Pagnotti1, V. Patel1, M. Altieri2, A. Pryor2, D. Telem2, M. Chan1, and C. Rubin1 Stony Brook University, Stony Brook, NY, 2Stony Brook University School of Medicine, Stony Brook, NY

1

Track: Orthopaedic and Rehabilitation Engineering, Device Technologies and Biomedical Robotics

Technology, Computer Interfaces and Wearable Devices Chairs: James Rains,Yahia Al-Smadi P-Th-114 Automatic Parameter Generation for Therapeutic Games Using Patient Assessment and Performance Data N. Sunny1 and J. Farris1 1

Grand Valley State University, Grand Rapids, MI

See page 92 for Poster floor plan

BMES 2014

121

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-115 EOG Based Human-Computer Interface for the Operation of a Text-ToSpeech App on Android Devices

P-Th-392 Organotypic 3D Liver Models for Investigating Drug Toxicity

J. Lara1, V. Contreras1, A. Heredia2, and R. Ambrosio1

1

Universidad Autónoma de Ciudad Juárez (UACJ), IIT, Ciudad Juárez, Mexico, 2Universidad Popular Autónoma del Estado de Puebla (UPAEP), Puebla, Mexico

1

P-Th-116 Utilization of Video Recording to Analyze Cognitive and Physical Facets of Children with Autism W. Goodwin1, J. Thakore1, J. McMahon1, A. N’goan1, and D. Shahmirzadi1 Stevens Institute of Technology, Hoboken, NJ

1

P-Th-117 A Wearable Navigator For The Visually Impaired And Blind Population H. He1 and J. Tan1

Th

P-Th-118 Novel Eye-Tracking System for Control of Motorized Wheelchairs J. Ward1 and M. McCarthy2 Tulane University, Lake Charles, LA, 2Tulane University, Commerce Township, LA

1

P-Th-119 Blink Controlled Brain Computer Interface Using EEG O. Yetkin , C. Mont , K. Wallace , and M. Romero 1

Virginia Tech, Blacksburg, VA

P-Th-393 Designing an Inflamed and Fibrotic Microenvironment to Investigate Changes in Liver Sinusoidal Endothelial Function A. Ford1 and P. Rajagopalan1 1

Virginia Tech, Blacksburg, VA

P-Th-394 Effect of Decellularized Liver Matrix Proteins on Porcine Hepatocytes in Vitro R. Coronado1,2,3, J. Ong1, R. Christy3, W. Washburn2, and G. Halff2 University of Texas at San Antonio, San Antonio, TX, 2University of Texas Health Science Center at San Antonio, San Antonio, TX, 3US Army Institute of Surgical Research, JBSA Fort Sam Houston, TX

1

The University of Tennessee, Knoxville, TN

1

Poster Session

S. Orbach1, M. Cassin1, and P. Rajagopalan1

1

1

1

University of Texas at Arlington, Arlington, TX

1

P-Th-120 Motor Rehabilitation Care for Children with Cerebral Palsy Using Telemedicine. P. Rodriguez1, E. Hernandez1, S. Montes1, and K. Bustamante1 ITESM Chihuahua, Chihuahua, Mexico

1

P-Th-121 Translational Research in the Development of Gait Rehabilitation Trainer M. Lee1, W. Song1, S. Sagong1, J. Seo1, and S. Eun1 National Rehabilitation Center, Seoul, Korea, Republic of

1

P-Th-122 Novel Design of an Anterior Cruciate Ligament (ACL) Injury Prevention Brace

P-Th-395 Novel Integrated In Vitro Gastrointestinal and Hepatic Models for Investigating Drug Toxicity R. Less1 and P. Rajagopalan1 1

Virginia Tech, Blacksburg, VA

P-Th-396 Analysis Of Perfusion-Enhanced Diffusion, Shear Damage And Metabolic Function In Spheroid-Seeded And Suspension-Seeded Hepatocyte Scaffolds D. Alzebdeh1 and H. Matthew1 1

Wayne State University, Detroit, MI

P-Th-397 Decellularized Liver Matrix Coating and Hydrogel for Culture and Transplantation of Hepatocytes J. Lee1, K. Lee1, J. Shin1, and S-W. Cho1 1

Yonsei University, Seoul, Korea, Republic of

P-Th-398 Is Hanging Monoculture of Primary Hepatocytes Better? Y. Kang1, J. Lamontagne1, Y. Cai1, M. Bouchard1, and H. Noh1 1

Drexel University, Philadelphia, PA

D. Greenshields1, R. Porter1, J. Killewald1, and E. Meyer1 1

Lawrence Technological University, Southfield, MI

P-Th-123 Variable Resistance Rehabilitative Knee Brace S. Dreyer1, D. O'Neill1, U. Acar1, K. Izak1, A. Patel1, and S. Piller1 University of Illinois at Chicago, Chicago, IL

1

P-Th-124 MEMS Flexible Strain Sensors for Arthritis Diagnosis K. Shinde1, J. Julius1, S. Rao1, and J-C. Chiao1 UT Arlington, Arlington, TX

1

Track: Tissue Engineering

Neural, Epithelial and Adipose Tissue Engineering Chairs: Sarah Stabenfeldt, John Frampton P-Th-401 Neurotrophic Factor Gradient Delivery to Direct Schwann Cell Migration K. Krick1, Y-J. Huang2, R. Martin2, P. Searson2, A. Khademhosseini3, A. Hoke1, and H-Q. Mao2 Johns Hopkins School of Medicine, Baltimore, MD, 2Johns Hopkins University, Baltimore, MD, 3Harvard-MIT, Cambridge, MA

1

Track: Tissue Engineering

Hepatic, Pancreatic, Digestive and Renal Tissue Engineering Chairs: Gregory Underhill, Srivatsan Kidambi P-Th-391 Evaluation of Oxygen Demand in Three Dimensional Culture of Pancreatic beta-cells J. McReynolds1, X. Li2, J. Guan2, and S. Jin1,3 University of Arkansas, Fayetteville, AR, 2The Ohio State University, Columbus, OH, Current: SUNY at Binghamton, Binghamton, NY

1 3

P-Th-402 Inducing Inner Ear Hair Cell Development by Seeding Reprogrammed Human Wharton's Jelly Cells on Decellularized Cochlea P-Th-403 FGF-Immobilized Multifunctional Microspheres for the Delivery of Neural Stem Cells N. Skop1, F. Calderona1, C. Gandhi1, S. Levison1, and C. Cho2 1

P-Th-404 Development of an In Vitro 3D Neuroinflammation Model H. Cho1 and Y. Lee1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

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Rutgers University, Newark, NJ, 2New Jersey Institute of Technology, Newark, NJ

Virginia Tech, Blacksburg, VA

9:30am – 5:00pm Poster Session Thurs   Poster Viewing with Authors & Refreshment Break  | 9:30am

P-Th-405 Nanochannel-Based Electrotransfection of Skin Cells In Situ D. Gallego-Perez1, S. Ghatak1, D. Pal1, N. Ahmed1, V. Malkoc1, X. Zhao1, J. Ma1, X. Wang1, S. Gnyawali1, S. Khanna1, C. Rink1, J. Otero1, L. Lee1, and C. Sen1 1

The Ohio State University, Columbus, OH

D. Wu1, S. Pradhan-Bhatt2, D. Harrington1, R. Witt3, and M. Farach-Carson1 Rice University, Houston, TX, 2University of Delaware, Newark, DE, 3Thomas Jefferson University, Philadelphia, PA

1

P-Th-407 The Effect of Enzymatic Pretreatment on Adipose Tissue Graft Viability Y. Cao , S. Seaman , S. Tannan , K. Lin , and S. Peirce 1

1

1

1

- 10:30am, 3:30pm - 4:30pm P-Th-142 Tissue Engineered Cartilage Interaction in Healthy and Diseased Environment Using Hydroxyapatite Nanoparticles R. Dua1, C. Siyambalapitiya1, A. Agarwal1, and S. Ramaswamy1 1

P-Th-406 Coordinated Cellular Interplay in 3D Reorganization of Human Parotid Salivary Gland Cells

1

1

University of Virginia, Charlottesville, VA

2014 | october 23 | Thursday

Florida International University, Miami, FL

P-Th-143 Utilizing Engineered Microporosity to Support Recellularization and Prepare a Porcine Derived Temporomandibular Joint Disc Scaffold for Tissue Engineering A. Matuska1 and P. McFetridge1 1

University of Florida, Gainesville, FL

P-Th-144 In Vitro Evaluation of the Endochondral Bone Formation on PCL Ceramic Composites S. Schussler1 1

Poster Session

New Jersey Institute of Technology, Newark, NJ

Track: Tissue Engineering, Orthopaedic and Rehabilitation Engineering

P-Th-145 Enhancing Bone Regeneration with Composite Microspheres that Reflect the Osteogenic Niche

Skeletomuscular Tissue Engineering

C. Haase1, C. Dodson1, C. Gregory2, and R. Kaunas1

Chairs: Sangamesh Kumbar, John Fisher

Texas A&M University, College Station, TX, 2Institute for Regenerative Medicine Texas A&M Health Science Center, Temple, TX

P-Th-135 Characterization f Polysaccharide Based Micro-Nano Structured Scaffolds for Osteoinductivity

P-Th-146 Modeling the Effects of Matrix Stiffness on Cartilage Formation in 3D Hydrogels

A. Aravamudhan1,2, D. Ramos1, M. Harmon1, and S. Kumbar1

D. Zhu1, A. Buganza Tepole1, E. Kuhl1, and F. Yang1

Institute For Regenerative Engineering, Farmington, CT, 2University of Connecticut, Farmington- Storrs, CT

1

1

P-Th-136 Assessing the Osteogenic Differentiation of Human Mesenchymal Stem Cells Co-Cultured with Human Vein Endothelial Cells on a Peptide Amphiphile Nanomatrix D. Patel 1, L. Deng1, J. Vines1, and H-W. Jun1 1

Stanford. University, Stanford, CA

P-Th-147 Effects of Proteoglycan Removal on Decellularization of Articular Cartilage C. Bautista1, H. Park1, and B. Bilgen2,3 Brown University, Providence, RI, 2Providence VA Medical Center, Providence, RI, 3The Warren Alpert Medical School of Brown University & Rhode Island Hospital, Providence, RI

1

P-Th-148 Vascularized Bone Grafts: Scaffold Design and Characterization

University of Alabama at Birmingham, Birmingham, AL

P-Th-137 The Development and Characterization of a Pre-Vascularized Biomimetic Cortical Bone Scaffold B. Taylor1 and J. Freeman1 1

1

Rutgers, the State University of New Jersey, Piscataway, NJ

P-Th-138 Dual Differentiation of Mesenchymal Stem Cells Can Be Obtained by Scaffold Characteristics H. Park1, S. Park2, Y. Kang2, J. Shin2, S. Gu1, Y-R. Wu2, and J-W. Shin1,2,3 Department of Helth Science and Techonology, Inje University, Gimhae-si, Korea, Republic of, 2Department of Biomedical Engineering, Inje University, Gimhae-si, Korea, Republic of, 3Cardiovascular and Metabolic Disease Center/Institute of Aged Life Redesign/UHRC, Gimhae-si, Korea, Republic of

C. Piard1 and J. Fisher1 1

University of Maryland, College Park, MD

P-Th-149 Patterns of IHP Can Effectively Control Osteogenesis of hMSCs Rather than Osteogenic Media Y. Kang1, S. Park1, J. Shin1, S. Gu2, H. Park2, H. Ban1, and J-W. Shin1,2,3 Department of Biomedical Engineering, Inje University, Gimhae-si, Korea, Republic of, Department of Health Science and Technology, Inje University, Gimhae-si, Korea, Republic of, 3Cardiovascular and Metabolic Disease Center /Institute of Aged Life Redesign/UHRC, Inje University, Gimhae-si, Korea, Republic of

1 2

1

P-Th-139 Chondroinductive Microsphere Based Scaffolds With Decellularized Cartilage For Cartilage Tissue Engineering A. Sutherland1, V. Gupta1, and M. Detamore1 1

University of Kansas, Lawrence, KS

S. Cameron1, S. Ayad1, B. Vendra1, D. Mason1, I. Khatri1, and R. OlivaresNavarrete1 Virginia Commonwealth University, Richmond, VA

1

Northeastern University, Boston, MA

UConn Health Center, Farmington, CT

1

P-Th-151 Tendon Differentiation Using Human Recombinant Insulin Institute For Regenerative Engineering, Farmington, CT, 2University of Connecticut, Farmington-Storrs, CT

1

P-Th-152 Multilayered Electrospun Silk Scaffolds Capable Of Eluting Platelet-Rich Plasma For Ligament Engineering P. Somasundaram1 and S. Sell1

P-Th-141 MgO Nanoparticles Enhance Osteoblast Functions on Hydroxyapatite Nanocomposites for Antibacterial Orthopedic Tissue Engineering Applications D. Hickey1, B. Ercan1, L. Sun1, and T. Webster1

E. Carbone1, H. Kan1, C. Laurencin1, and W. Lo1

D. Ramos1,2, C. Laurencin1,2, and S. Kumbar1,2

P-Th-140 Topographical Cues on Biomimetic Electrospun Scaffolds for Bone Tissue Engineering 1

P-Th-150 Engineered Bone Tissue Through Short-term Administration of an Osteogenic Small Molecule

Saint Louis University, St. Louis, MO

1

P-Th-153 The Fabrication of Dense, Porous and Aligned Collagen Scaffolds using Novel 2D Plastic Compression and Porogen Based Techniques S. Reese1, J. Zitnay2, D. Rojas-Leon1, and J. Weiss1 University of Utah, Salt Lake City, UT, 2University of Minnesota, Minneapolis, MN

1

See page 92 for Poster floor plan

BMES 2014

123

Th

Thursday | october 23 | 2014

Poster Session Thurs 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am, 3:30pm - 4:30pm P-Th-154 Human Skeletal Muscle Bundle Model and Perfusion System

P-Th-378 Long-Term Engineered Cultures of Primary Mouse Hepatocytes for Genotype-Phenotype Studies

B. Davis1, J. Santoso1, and G. Truskey1 1

B. Ware1, V. Soldatow2, D. Berger1, E. LeCluyse2, and S. Khetani1

Duke University, Durham, NC

P-Th-155 Development of Spatially Patterned Extracellular Matrix Cues to Direct the Differentiation and Alignment of Human Skeletal Muscle Tissue R. Duffy1, L. Friedman1, and A. Feinberg1 1

Carnegie Mellon University, Pittsburgh, PA

Colorado State University, Fort Collins, CO, 2The Hamner Institutes for Health Sciences, Research Triangle Park, NC

1

P-Th-379 Mimicking Chronic Hypo- and Hyper-glycemia in Engineered Cultures of Human Hepatocytes M. Davidson1, K. Ballinger 1, and S. Khetani1 1

Track: Tissue Engineering

Poster Session

Th

Tissue Engineering of Models for Study of Disease and Drug Discovery Chairs: Agneta Simoinescu, Scott Verbridge

)

P-Th-370 Analysis of Non-Enzymatic Collagen Crosslinks in Engineered Cell-Secreted Extracellular Matrices D. Mitra1, H. Fatakdawala1, L. Marcu1, and J. Leach1 1

University of California, Davis, CA

P-Th-371 Tissue Engineering an In Vitro Model of Fibrosis in Skeletal Muscle A. Marinkovic1,2, C. Neville1, O. Mwizerwa1, K. Vivanco3, I. Pomerantseva1, J. Kohn2, J. Vacanti2, and C. Sundback1 Massachusetts General Hospital, Boston, MA, 2New Jersey Center for Biomaterials, Piscataway, NJ, 3Massachusetts Institute of Technology, Cambridge, MA

1

P-Th-372 Improving Anastomosis Between Microfluidic Channels And Perfused Capillary Networks In Cultured 3D Human Microtissues. D. Phan1,2, X. Wang1,2, A. Lee1, S. George1,2, and C. Hughes1,2 University of California, Irvine, Irvine, CA, 2The Edwards Lifesciences Center for Advanced Cardiovascular Technology, Irvine, CA

1

P-Th-373 The Inhibitory Effects of Fibrosis on Muscle Regeneration in a SelfAssembled Tissue Engineered Model of Skeletal Muscle J. Krieger1, J. Rankenberg1, B-W. Park2, J. Forte2, M. Rolle2, R. Page2, and C. Malcuit1 1

Kent State University, Kent, OH, 2Worcester Polytechnic Institute, Worcester, MA

P-Th-374 Investigating the Influence of Intercellular Signaling on Angiogenesis M. Gadde1, M. Rylander1, and 1

Virginia Polytechnic Institute and State University, Blacksburg, VA

P-Th-375 Controlling Ferrofluid Permeability Across the in vitro Blood-Brain Barrier Model via Different Coatings D. Shi , L. Sun , G. Mi , S. Bhattacharya , S. Nayar , and T. Webster 1

1

1

2

2

Northeastern University, Boston, MA, 2CSIR-National Metallurgical Laboratory, Jamshedpur, India

P-Th-376 Improving Liver Functions of Hepatic Cell Lines in vitro by Co-Culture with Stromal Support Cells K. Ballinger , A. Bailey , and S. Khetani 1

1

1

Colorado State University, Fort Collins, CO

P-Th-377 Exploring Chronic Drug Dosing in Engineered Human Liver Cultures Using Global Expression Profiling D. Berger , M. McVay , and S. Khetani 1

1

2

1

Colorado State University, Fort Collins, CO, 2Hepregen Corporation, Medford, MA

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

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BMES 2014

L. McCallum1, J. Schulte1, and A. Simionescu1 1

Clemson University, Clemson, SC

P-Th-381 Magnetic Nanoshuttle for the Rapid Assembly of Functional Multicellular Cardiac Aggregates M. Hogan1, G. Souza2, and R. Birla1 1

University of Houston, Houston, TX, 2Nano3D Biosciences, Houston, TX

P-Th-382 Investigation Of Circadian Rhythms Perturbation by Metabolic Stimulation in Peripheral Tissues through Microfluidic Technology O. Gagliano1,2 1

University of Padova, Padova, Italy, 2Venetian Institute of Molecular Medicine, Padova, Italy

P-Th-383 Development of An Integrated Bronchio-Alveolar Organ Construct for Understanding Pulmonary Drug Toxicity J-H. Huang1, P. Nath1, A. Arefin2, J. Harris1, and R. Iyer1 Los Alamos National Laboratory, Los Alamos, NM, 2University of New Mexico, Albuquerque, NM

1

P-Th-384 3D Tumor Microtissue for Drug Discovery E. Atefi1, S. Lemmo1, D. Fyffe1, and H. Tavana1 1

The University of Akron, Akron, OH

P-Th-385 An in-vitro Biomimetic, Fluid-Dynamic 3D Model of the Human Intestine for Evaluating Oral Drug Delivery E. Schlesinger1, A. Cerchiari1, J. Kim1, and T. Desai2 UC Berkeley - UCSF, San Francisco, CA, 2University of California, San Francisco, San Francisco, CA

1

P-Th-386 Porous Poly Urethane Microspheres as a 3-D Culture Model for In Vitro Drug Screening J. Menon1, A. Kuriakose1, K. Pokhrel1, A. Sharma1, Y. Hong1, and K. Nguyen1 University of Texas at Arlington, University of Southwestern Medical Center at Dallas, Arlington, TX

1

1

1

1

Colorado State University, Fort Collins, CO

P-Th-380 Tissue Engineering Models for the Study of Diabetic Cardiomyopathy

P-Th-387 Ex Vivo Tissue Test Systems: Novel Layered Scaffold Design Offers Unique Analysis S. Rowlinson1, K. Kwist1, and K. Burg1 1

Clemson University, Clemson, SC

P-Th-388 Acoustic Characterization of a Novel Scaffold-Based System for Investigations on Sonoporation A. Aleid1, A. Alassaf 1, O. Wilson, Jr.1, and V. Frenkel1 1

The Catholic University of America, Washington, DC

8:00AM-9:30aM Platform Sessions Fri-1

FRIDAY, October 24, 2014

TODAY’S HIGHLIGHT

8:00 AM - 9:30 AM PLATFORM SESSIONS – Fri - 1

PLATFORM SESSIONS Fri-1 8:00am - 9:30am See pages 125-131, HBGCC

EXHIBIT HALL OPEN

2014 | october 24 | Friday

9:30am - 5:00pm

WSCC, Exhibit Hall A

Track: Tissue Engineering, Neural Engineering OP-Fri-1-1 - Room 001A

Neural Tissue Engineering

POSTER SESSION Fri 9:30am - 5:00pm See pages 1429-173, WSCC, Exhibit Hall A

Chairs: Stuart Tobet, Deanna Thompson

Poster Viewing with Authors 9:30am - 10:30am & Refreshment Break

Engineering Personalized Neural Tissue by Combining Induced Pluripotent Stem Cells with Fibrin Scaffolds

8:00AM

A. Montgomery1, A. Wong1, N. Gabers1, and S. Willerth1 1

PLENARY SESSION

University of Victoria, Victoria, BC, Canada

8:30AM

10:30am - 12:00noon

Rapid 3D Assays for Combinatorial Screening of Biomaterials Platform Sessions

C. Bertucci1, S. Ramamoorthy1, P. Karande1, and D. Thompson1 Rensselaer Polytechnic Institute, Troy, NY

HBGCC, Lila Cockrell Theatre

1

NIH NIBIB Lecture David Kaplan, PhD

Ocular Tissue Engineering with Fetal Brain Derived Extracellular Matrix Bioscaffolds

8:45AM

C. Medberry1, V. Reddy1, A. Faust1, F. Mehdi1, and M. Steketee1 1

WOMEN IN BME Luncheon

12:15pm - 1:30pm

HBGCC, Ballroom A

Additional ticket purchase required

9:00AM

A 3D Electrospun Fiber and Hydrogel Composite Scaffold for Brain Regeneration C. Johnson1, C. Rivet1, K. Zhou2, R. Gilbert1, D. Finkelstein3, and J. Forsythe2 1

PLATFORM SESSIONS Fri-2 1:45pm - 2:45pm See pages 132-136, HBGCC

PLATFORM SESSION Fri-3

University of Pittsburgh, Pittsburgh, PA

3

Rensselaer Polytechnic Institute, Troy, NY, 2Monash University, Melbourne, Australia, University of Melbourne, Melbourne, Australia

9:15AM 3:00pm - 4:00pm

See pages 137-140, HBGCC

Hydrophilic Surface Modification of Electrospun Fibers for Nerve Guidance N. Schaub1, C. Le Beux2, J. Maio1, R. Linhardt1, J. Alauzun2, D. Laurencin2, and R. Gilbert1

Poster Viewing with Authors 4:00pm - 5:00pm & Refreshment Break HGBCC, Exhibit Hall A

1 Rensselaer Polytechnic Institute, Troy, NY, 2Institut Charles Gerhardt de Montpellier, Montpellier, France

Track: Neural Engineering OP-Fri-1-2 - Room 001B

PLENARY SESSION

5:15pm - 6:15pm HBGCC, Lila Cockrell Theatre Stephen Oesterle, MD

CNS injury: SCI, TBI and Concussion Chairs: Mark Van Dyke, Randolph Ashton 8:00AM

Sustained In Vivo Dual Drug Delivery of Anti-Inhibitory Molecules for Spinal Cord Injury Treatment T. Wilems1, C. Ingram1, and S. Sakiyama-Elbert1 1

Washington University in St. Louis, St. Louis, MO

8:15AM

Digitally Controlling the Biomechanics of Fluid Percussion Injury M. Long1,2, N. Peloso1, and B. Pfister1 New Jersey Institute of Technology, Newark, NJ, 2Rutgers Biomedical and Health Sciences, Newark, NJ

1

8:30AM

Local and Sustained Delivery of BDNF Mediates Spinal Learning after Injury Z. Khaing1, J. Park 2, J. Grau3, K. Lee3, A. Niemerski3, and C. Schmidt2 University of Florida, Gainesville, FL, 2University of Florida, Gainesville, GA, 3Texas A&M, College Station, TX

1

BMES BASH

7:00pm - 10:00pm

Buckhorn Saloon & Texas Ranger Museum BMES 2014

125

Fri-1

Friday | OCTOBER 24 | 2014

Platform Sessions Fri-1 8:00AM-9:30aM

8:45AM

Local Delivery of Minocycline from Injectable Hydrogel Loaded with Self-Assembled Complexes Effectively Promotes Neuroprotection after Contusive Spinal Cord Injury Z. Wang1, K. Wofford1, Z. Zhang1, and Y. Zhong1 1

Drexel University, Philadelphia, PA

9:00AM

Evaluation of Nanocarrier Delivery and a Novel Anti-inflammatory Drug for Spinal Cord Injury T. Saxena1, K. Loomis1, B. Pai1, L. Karumbaiah1, E. Gaupp1, K. Patil1, R. Patkar1, and R. Bellamkonda1 1

Georgia Institute of Technology, Atlanta, GA

Track: Cardiovascular Engineering OP-Fri-1-4 - Room 006B

Cardiac Electrophysioloy and Mechanics Chairs: Adam Engler, Jeffrey Jacot 8:00AM

Ephaptic Coupling and Its Complex Role in Maintaining Cardiac Conduction S. George1, K. Sciuto2, J. Lin3, M. Salama2, J. Keener2, R. Gourdie1,4, and S. Poelzing1,4 Virginia Polytechnic Institute and State University, Blacksburg, VA, 2University of Utah, Salt Lake City, UT, 3California Polytechnic State University, San Luis Obispo, CA, 4Virginia Tech Carilion Research Institute, Roanoke, VA

1

9:15AM

Transient Hypoxia in a Model of Distraction Spinal Cord Injury Results in a Reduction of Ventral Motor Neuron Size J. Seifert1,2, J. Bell1,2, D. Sucato3, and M. Romero1,2 UT Arlington, Arlington, TX, 2UT Southwestern, Dallas, TX, 3Texas Scottish Rite Hospital for Children, Dallas, TX

1

8:15AM

Cell Size and Shape as Determinants of Ion Channel Distribution and Function S. Sengupta1, B. Hoffman1, and N. Bursac1 1

Platform Sessions

Fri-1

Track: Biomaterials, Cellular and Molecular Bioengineering OP-Fri-1-3 - Room 006A

Intelligent/Multifunctional Biomaterials Chairs: Melissa Grunlan, Craig Duvall 8:00AM

Biomimetic, Monocyte-targeting Supramolecular Micellar Assemblies for Atherosclerosis Theranostics E. Chung1, L. Mlinar2, K. Nord1, M. Sugimoto1, E. Wonder1, C. Zhang1, C-H. Kuo1, J. Andrade1, Y. Fang1, L. Huang1, F. Alenghat1, and M. Tirrell1 1

University of Chicago, Chicago, IL, 2University of California, Berkeley, Berkeley, CA

8:15AM

Duke University, Durham, NC

8:30AM

Recellularized Cardiac Tissue Slices Produce Aligned Cells and Anisotropic Conduction A. Blazeski1, G. Kostecki1, and L. Tung1 1

Johns Hopkins University, Baltimore, MD

8:45AM

Cycle Length Restitution and Spontaneous Action Potential Dynamics in Sinoatrial Node Disease P. Glynn1, B. Onal1, and T. Hund1 1

The Ohio State University, Columbus, OH

9:00AM

Control of Cardiac Alternans using Boundary Pacing and Mechanical Perturbations Control

Non-Invasive Deep Tissue Imaging of Polymer Degradation Using X-Ray

A. hazim1, S. Dubljevic1, and Y. belhamadia1

T. Olsen1, D. Whitehead1, B. Van Horn2, and F. Alexis1

9:15AM

1

Clemson University, Clemson, SC, 2College of Charleston, Charleston, SC

8:30AM

Molecularly Responsive Biomaterials Based on DNA-Crosslinked Hydrogels: Assembly and Applications T. Betancourt1, R. Navarro1, R. Danso1, K. Beaven1, R. Hall1, K. Knutson1, and K. Abdelrahman1 1

Texas State University, San Marcos, TX

8:45AM

Thiol-ene Networks As Hydrolytically Stable, Ultra-soft Neural Prosthetic Substrates R. Reit1, D. Simon1, B. Lund1, T. Ware1, and W. Voit1 1

University of Texas at Dallas, Richardson, TX

9:00AM

Magnetic Mesoporous Hollow Carbon Microspheres for Rapid Capture of Low-concentration Peptides G. Cheng1, M-D. Zhou1, and S-Y. Zheng1 1

Electrochemically Modulated Nitric Oxide (NO) Releasing Biomedical Devices via Copper(II)-Tri(2-pyridylmethyl)amine Mediated Reduction of Nitrite H. Ren1, J. Wu1, C. Xi1, N. Lehnert1, T. Major1, R. Bartlett1, and M. Meyerhoff1 University of Michigan, Ann Arbor, MI

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

126

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University of Alberta, Edmonton, AB, Canada

Effect of Substrate Stiffness on Cardiac Fibroblasts Isolated from Volume-Overload Induced Heart Failure R. Childers1, P. Lucchesi2, and K. Gooch1 The Ohio State University, Columbus, OH, 2Research Institute of Nationwide Children's Hospital, Columbus, OH

1

Track: Drug Delivery OP-Fri-1-5 - Room 006C

Nucleic Acid Delivery Chairs: Debra Auguste, Blanka Sharma 8:00AM Invited

DNA and RNA Release Surfaces for Systemic and Localized Delivery Applications P. Hammond1 1

Penn State University, State College, PA

9:15AM

1

1

Massachusetts Institute of Technology, Cambridge, MA

8:30AM

Antibody-conjugated Nanoparticle Platform for Targeted Delivery of SiRNA to HER2+ Breast Cancer W. Ngamcherdtrakul1, J. Morry1, S. Gu1, D. Castro1,2, T. Sangvanich1, S. Goodyear1, Z. Hu1, J. Gray1, and W. Yantasee1,2 Oregon Health and Science University, Portland, OR, 2PDX Pharmaceuticals, LLC, Lake Oswego, OR

1

8:00AM-9:30aM Platform Sessions Fri-1

2014 | october 24 | Friday

8:45AM

Silencing of Tumor Necrosis Factor Receptor-1 in Human Lung Microvascular Endothelial Cells Using Particle Platforms for siRNA Delivery J. Sakamoto1, L. Bai1, D. Chan1, S. Shamsudeen1, and R. Serda2 1

Houston Methodist, Houston, TX, 2Baylor College of Medicine, Houston, TX

9:00AM

Engineering Exosomes for DNA Delivery T. Lamichhane1, R. Raiker1, and S. Jay1 1

University of Maryland, College Park, MD

9:15AM

Nasal Delivery of MicroRNA-486 via Surfactant Protein-C Targeted Lipoplexes in Lung Cancer Treatment Y. Wu1,2, A. Gaughan3, J. Ma2, S. Nana-Sinkam2, L. Lee2, and I. Davis3 State University of New York at Buffalo, Buffalo, NY, 2The Ohio State University, Columbus, OH, 3The Ohio State Unviersity, Columbus, OH

1

Track: Cancer Technologies OP-Fri-1-7 - Room 007A

Engineered Models of Cancer I Chairs: Nastaran Kuhn, Esther Gomez 8:00AM

An Agent-Based Model Based On Breast Cancer Receptor Heterogeneity K-A. Norton1, N. Pandey1, and A. Popel1 1

Johns Hopkins University, Baltimore, MD

8:15AM

Development of a Versatile Platform to Analyze Glioma Specimens S. Pedron1, M. Schroeder2, J. Sarkaria2, and B. Harley1 1

University of Illinois at Urbana-Champaign, Urbana, IL, 2Mayo Clinic, Rochester, MN

8:30AM

Track: Translational Biomedical Engineering, Nano to Micro Technologies OP-Fri-1-6 - Room 006D

Multiplex Fluorescence Lifetime Imaging of Kinase activity in Live Cells with Peptide Biosensors

Bio-nanomedicine in Healthcare

8:45AM

Chairs: Kent Leach, Manu Platt 8:00AM Invited

Translating Promising Academic Medical Concepts to Products: Consider Success Criteria Beforehand A. Coury1 1

Northeastern University, Boston, MA

8:30AM

Platform Anti-NF-&[kappa]B Nanotechnology for Virally Driven Adult T-Cell Leukemia/Lymphoma H. Pan1, K. Hou1, D. Rauch1, J. Harding1, L. Ratner1, and S. Wickline1 1

Washington University School of Medicine, St Louis, MO

  8:45AM

Intravenously Administered Nanoparticles Improve Cognitive Outcomes Following Blast Trauma W. Hubbard1, M. Lashof-Sullivan2, C. Hall1, E. Lavik2, and P. VandeVord1,3 Virginia Polytechnic Institute and State University, Blacksburg, VA, 2Case Western Reserve University, Cleveland, OH, 3Salem VA Medical Center, Research & Development Service, Salem, VA

1

9:00AM

Inhibition of Various Bacterial Growth on Selenium Nanoparticle Coated Paper Towels Q. Wang1 and T. Webster1 1

Northeastern University, Boston, MA

9:15AM

TheraBlob for Ultrasound-mediated Ablation Therapy S. Misra1,2, M. Ye1,2, P. Ray2, and D. Pan1,2,3 University of Illinois at Urbana-Champaign, Urbana, IL, 2Carle Foundation Hospital, Urbana, IL, 3Beckman Institute, Urbana, IL

1

N. Damayanti1, L. Parker1, and J. Irudayaraj1 1

Purdue University, West Lafayette, IN

Fri-1

Genome Edited Cell Models to Investigate Epigenetic Fluctuation and Cancer Initiation I. Xhangolli1, J. Chen1, Y. Wu1, Y. Maruvka2, F. Michor2, and R. Fan1 1

Yale University, New Haven, CT, 2Dana Farber Cancer Institute, Boston, MA

9:00AM

Physical Intimacy of Breast Cancer Cells and Mesenchymal Stem Cells Regulates Drug Resistance Pathways A. Daverey1, A. Drain1, K. Brown1, and S. Kidambi1 1

University of Nebraska-Lincoln, Lincoln, NE

9:15AM

3D Bone Marrow Mimics to Study Stem Cell-Mediated Breast Cancer Spread L. Jansen1, L. Barney1, T. McCarthy1, and S. Peyton1 1

University of Massachusetts Amherst, Amherst, MA

Track: Cardiovascular Engineering, Device Technologies and Biomedical Robotics OP-Fri-1-8 - Room 007B

Cardiovascular Assist Devices Chairs: Marc Horner, Danny Bluestein 8:00AM

Physiological Characterization of the Total Artificial Heart J. Crosby1, K. DeCook1, P. Tran1, R. Smith1, D. Burkhoff2, and M. Slepian1 1

The University of Arizona, Tucson, AZ, 2Columbia University, New York, NY

8:15AM

Numerical Model of Full Cardiac Cycle Hemodynamics in Syncardia Total Artificial Heart G. Marom1, W-C. Chiu1, S. Prabhakar2, M. Horner3, M. Slepian1,4, and D. Bluestein1 Stony Brook University, Stony Brook, NY, 2Ansys Fluent India Pvt. Ltd, Pune, India, 3Ansys, Inc., Evanston, IL, 4University of Arizona, Tucson, AZ

1

8:30AM

Demonstration of Low Frequency Speed Modulation of Miniature Rotary Blood Pumps in a Large Animal Model K. Soucy1, G. Giridharan1, M. Sobieski1, M. Slaughter1, and S. Koenig1 1

Platform Sessions

University of Louisville, Louisville, KY

BMES 2014

127

Friday | OCTOBER 24 | 2014

Platform Sessions Fri-1 8:00AM-9:30aM

8:45AM

High Speed Flow Visualization Reveals Thrombogenic Pathlines in Axial Flow Blood Pump F. Yang and J. Antaki 1

1

1

Carnegie Mellon University, Pittsburgh, PA

9:00AM

Reduced Platelet Aggregation Following High Shear Exposure A. Houzelle1, C. Lewis1, T. Snyder2, and D. Schmidtke1 1

University of Oklahoma, Norman, OK, 2Integris, Oklahoma City, OK

Investigating VWF Degradation as a Result of Integrated Shear Stress Patterns Illinois Institute of Technology, Chicago, IL

Track: Cellular and Molecular Bioengineering OP-Fri-1-9 - Room 007C

Fri-1

Molecular and Cell Engineering I Chairs: Nic Leipzig, Eric Boder

8:00AM

S. Iyer1, K. Montgomery1, and S. Delp1 1

Stanford University, Stanford, CA

Luminescent IVIS Imaging of NF-1κ B Activity as a Biomarker of Inflammation Driven Pain R. Bowles1 and L. Setton1 1

Duke University, Durham, NC

8:30AM

Experimental Disc Herniation Radiculopathy Requires Intraneural Macrophage Infiltration and can be Blocked by Strategies Limiting Macrophage Function M. Shamji1,2, Y. Tu3, and M. Salter3

8:00AM

Molecular Mechanism of Suppressed Cell Spreading in Tumor Repopulating Cells F. Chowdhury1, N. Wang1, and T. Ha1 1

Chairs: Lori Setton, Beth Winkelstein

8:15AM

S. Yang1 and V. Turitto1

Platform Sessions

Pain Optogenetic Methods to Stimulate and Inhibit Pain in Mice

9:15AM

1

Track: Orthopaedic and Rehabilitation Engineering OP-Fri-1-10 - Room 007D

University of Illinois at Urbana-Champaign, Urbana, IL

8:15AM

Flu X-Hemagglutinin with Ablated Immunodominant Epitopes Protects Mice Against Lethal H5N1 Challenge S. Bock1, A. Lu1, R. dela Cruz1, J. Jenson1, J. Marcos1, D. Barnard2, and B. Tarbet2 University of Utah, Salt Lake City, UT, 2Utah State University, Logan, UT

1

1 University of Toronto, Toronto, ON, Canada, 2Toronto Western Hospital, Toronto, ON, Canada, 3Hospital for Sick Children, Toronto, ON, Canada

8:45AM

Neuronal Activity in the CNS Modulates Persistent Pain: Mechanisms & Therapeutic Potential B. Winkelstein1, N. Crosby1, P. Syre1, K. Nicholson1, and C. Weisshaar1 1

University of Pennsylvania, Philadelphia, PA

9:00AM

Reducing Pain and Improving Function in Patellofemoral Pain Synchome through Offaxis Training L-Q. Zhang1 and L. Tsai1

8:30AM

Engineering Immune Cell Function Using a Vector-Free Microfluidic Delivery Platform A. Sharei1,2,3, R. Trifonova1, S. Jhunjhunwala3, S. Mao3, G. Hartoularos3, A. Eyerman3, P. Basto3, J. Lieberman1, D. Irvine3, D. Anderson3, U. von Andrian1, R. Langer3, and K. Jensen3 Harvard Medical School, Boston, MA, 2Ragon Institute, Cambridge, MA, 3Massachusetts Institute of Technology, Cambridge, MA

1

1

Northwestern University, Chicago, IL

9:15AM

Advancing Gait Analysis Techniques for the Assessment of Pain and Disability in Rodent Preclinical Models of Joint Disease K. Allen1, H. Kloefkorn1, and B. Jacobs1 1

University of Florida, Gainesville, FL

8:45AM

Engineering T Lymphocytes with Protein Nanogels for Cancer Immunotherapy L. Tang , Y. Zheng , and D. Irvine , 1

1

1

1 2

MIT, Cambridge, MA, 2Howard Hughes Medical Institute, Chevy Chase, MD

Track: Nano to Micro Technologies OP-Fri-1-11 - Room 008A

Nanobiointerfaces

9:00AM

Chairs: Akhilesh Gaharwar, Adam Hall

C. Lee1, Y. Lin1, M. Preininger2, R. Cottle1, T. Cradick1, and G. Bao1

8:00AM

Increasing CRISPR Specificity For Therapeutic Applications 1

Georgia Institute of Technology, Atlanta, GA, 2Emory University, Atlanta, GA

9:15AM

Enhancing Biomolecular Screening By Combining Yeast Surface Display and Noncanonical Amino Acids J. Van Deventer1, R. Kelly1, D. Le1, J. Zhao1, and K. Wittrup1 1

Massachusetts Institute of Technology, Cambridge, MA

Evaluation of High-efficiency Optoelectronic Nanowires in Rabbits M. Khraiche1, L. Chen1, Y. Jing1, W. Freeman1, and G. Silva1 1

University of San Diego California, La Jolla, CA

8:30AM

Probing Astrocytes with Carbon Nanotubes and Assessing the Role of Glial Fibrillary Acidic Protein in their Effects on Astrocytic Morphology and Proliferation M. Gottipati1, E. Bekyarova2, M. Brenner1, R. Haddon2, and V. Parpura1 1

University of Alabama, Birmingham, AL, 2University of California, Riverside, CA

8:45AM

Detecting Single Molecule Dynamics Using a ZMW/Microfluidic Hybrid Chip Y. Zhao1, D. Chen1, S. Benkovic1, and T. Huang1 P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

128

BMES 2014

1

Pennsylvinia State University, State College, PA

8:00AM-9:30aM Platform Sessions Fri-1

2014 | october 24 | Friday

9:00AM

Heat-Shrunken Hierarchical Silica Nanomembrane for Solid Phase DNA Extraction Y. Zhang , Y. Zhang , K. Liu , and T-H. Wang , , , 1

1

2

1 3 4 5

Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 2Circulomics Inc., Baltimore, MD, 3Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, 4Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, 5Johns Hopkins Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD

1

Track: Device Technologies and Biomedical Robotics, New Frontiers and Special Topics OP-Fri-1-13 - Room 201

Wearable Technology Chairs: Youngjae Chun, John Hanks

9:15AM

8:00AM

X. Jiang1, J. Hu2, J. Biffinger3, L. Fitzgerald3, E. Petersen4, C. Jackan1, A. Lieber1, B. Ringeisen3, and C. Lieber1

J. Hanks1

Probing Single-Bacterium Level Charge Transport in Microbial Fuel Cells Harvard University, Cambridge, MA, 2Institute of Chemistry, Chinese Academy of Sciences, Beijing, China, People's Republic of, 3US Naval Research Laboratory, Washington, DC, 4 Nova Research, Inc., Alexandria, VA

Test Platform Accelerates Design of Fitness Bands, Smart Watches, and Wearable Devices 1

Texas A&M University, College Station, TX

1

8:30AM

Spectral Analyses as a Measure of Limb Coordination E. Wade1 and J. Chen1 1

Track: Tissue Engineering, Biomaterials OP-Fri-1-12 - Room 008B

Bone and Cartilage Tissue Engineering I Chairs: Fan Yang, Rene Olivares-Navarrete 8:00AM

Composite Tissue-Engineered Scaffolds for Cervical Disc Replacement in a Pre-Clinical Canine Model J. Mojica-Santiago1, P. Grunert, MD2, Y. Moriguchi, MD, PhD2, R. Hartl, MD2, and L. Bonassar, PhD1 1

Cornell University, Ithaca, NY, 2Weill Cornell Medical College, New York, NY

8:15AM

Small Peptide Isolated from Enamel Extracellular Matrix Induces Osteoblastic Differentiation in Mesenchymal Stem Cells R. Olivares-Navarrete1, S. Hyzy1, K. Vesper2, Z. Schwartz1, and B. Boyan1 Virginia Commonwealth University, Richmond, VA, 2Georgia Regents University, Augusta, GA

1

8:30AM

Diabetic Bone Regeneration Enhanced by Biodegradable Drug-Based Polymer and its Mechanisms W. Yu1, K. Wada2, M. Mattos2, D. Graves2, and K. Uhrich1 1

Rutgers University, Piscataway, NJ, 2University of Pennsylvania, Philadelphia, PA

Lysophosphatidic Acid Presentation From Engineered Fibrin Gels for Cell-Based Bone Formation B. Binder , M. Wilkinson , and J. Leach 1

1

1

University of California, Davis, Davis, CA

9:00AM

Inhibiting Inflammatory Signals Improves Stem Cell-based Bone Regeneration M. Martino1, K. Maruyama1, R. Muller2, and S. Akira1 1

8:45AM

Design and Validation of a Smart Knee Fixture for Measuring Knee Balancing

Osaka University, Osaka, Japan, 2ETHZ, Zurich, Switzerland

9:15AM

Fri-1

C. Bell1, P. Meere1, I. Borukhov1, and P. Walker1 1

NYU Hospital for Joint Diseases, New York, NY

9:00AM

Helmet Device for Optimized Mechanical Optical Clearing Enhancement of Near-Infrared Spectroscopy C. Idelson1, P. Repisky2, S. LaConte2,3,4, B. King-Casas2,3,4, and C. Rylander1,2 1 University of Texas, Austin, TX, 2Virginia Tech, Blacksburg, VA, 3Virginia Tech Carilion School of Medicine, Roanoke, VA, 4Virginia Tech Carilion Research Institute, Roanoke, VA

9:15AM

Wearable Biomechanical Sensor System for Vibration Exposure and Grip Force Measurements S. Kudernatsch1, T. Asaki1, and D. Peterson1 University of Connecticut Health Center, Farmington, CT

1

Track: Biomechanics, Biomaterials OP-Fri-1-14 - Room 103B

Mechanics of Biomaterials 8:00AM

Morphological and Mechanical Behavior of Fibrin Clots in Healthy, Diabetic, and Sickle Cell Anemia Disease States N. Fan1, M. Platt1, and R. Averett1 Georgia Institute of Technology, Atlanta, GA

1

8:15AM

Theoretical Analysis and Finite Element Implementation of a Transversely Isotropic Material Model for Soft Tissue with Two Anisotropic Invariants Y. Feng1, R. Okamoto2, G. Genin2, L. Taber2, and P. Bayly2

Citrate-Based Biphasic Scaffolds For The Repair Of Large Segmental Bone Defects

1

R. Tran1, Y. Guo2, D. Xie2, D. Nguyen1, X. Bai2, and J. Yang1

8:30AM

The Pennsylvania State University, University Park, PA, 2Southern Medical University, Guangzhou, China, People's Republic of

1

Platform Sessions

Chairs: Natalie Artzi, Wei Tan

8:45AM

1

University of Tennessee, Knoxville, TN

Soochow University, SuZhou, China, People's Republic of, 2Washington University in Saint Louis, Saint Louis, MO

Stress-Relaxation Behavior of a Novel Alginate/Polyacrylamide Hydrogel Material with Tunable Properties M. Fitzgerald1, J. Berberich1, and J. Sparks1 Miami University, Oxford, OH

1

BMES 2014

129

Friday | OCTOBER 24 | 2014

Platform Sessions Fri-1 8:00AM-9:30aM

8:45AM

Response of Isolated Bioprosthetic Heart Valve Biomaterials to In-Vivo Stress K. Feaver1, W. Zhang1, H. Tam2, M. Lee3, J. McGarvey3, C. Aoki3, S. Takebayashi3, N. Kondo3, R. Gorman3, J. Gorman III3, N. Vyavahare2, and M. Sacks1 University of Texas at Austin, Austin, TX, 2Clemson University, Clemson, SC, 3University of Pennsylvania, Philadelphia, PA

1

9:00AM

Biaxial Analysis of Synthetic Scaffolds for Hernia Repair Demonstrates Variability in Mechanical Anistropy, Non-linearity, and Hysteresis C. Deeken1, D. Thompson1, R. Castile1, and S. Lake1 1

Magnetic Resonance Imaging I Chairs: Bruce Damon, Timothy Duong 8:00AM

Imaging Renal Perfusion in Acute Kidney Injury at 3T Using 19F/1H MRI of Perfluorocarbon Nanoparticles M. Goette1, J. Chen1, C. Vemuri1, J. Allen1, S. Caruthers1,2, G. Lanza1, and S. Wickline1

Washington University in St. Louis, St. Louis, MO

1

9:15AM

Synchrotron X-Ray Scattering Reveals a Pivotal Role of Water in the Ultrastructural Mechanics of Bone J. Samuel1 and X. Wang1 1

Track: Biomedical Imaging and Optics OP-Fri-1-16 - Room 202B

8:15AM

Magnetic Resonance Imaging of Cardiac Activation in Heart Failure Patients with Left Bundle Branch Block D. Auger1, S. Cui1, X. Chen1, K. Bilchick1, and F. Epstein1

University of Texas at San Antonio, San Antonio, TX

1

Platform Sessions

Fri-1

Washington University in St. Louis, St. Louis, MO, 2Philips Healthcare, Cleveland, OH

University of Virginia, Charlottesville, VA

Track: Bioinformatics, Computational and Systems Biology OP-Fri-1-15 - Room 202A

8:30AM

Signaling Systems Analysis

S. Kanakia1, D. Minh Hoang2, J. Toussaint1, S. Mullick Chowdhury1, S. Lee1, K. Shroyer1, W. Moore1, Y. Zaim Wadhgiri2, and B. Sitharaman1

Chronic Toxicity of Dextran Functionalized Graphene Nanoparticles and Their Potential as Highly Efficacious Blood Pool Contrast Agent for Magnetic Resonance Imaging 1

Chairs: Benjamin Cosgrove, Scott Diamond

8:45AM

8:00AM Invited

Monitoring Bone Repair in a Mouse Calvarial Defect Model Using Magnetic Resonance Imaging

Systems Biology: High-throughput, Multiscale and Patient Specific

V. Khalilzad-Sharghi1, K. Wartella1, M. Kelso2, H. Xu1, and S. Othman1

S. Diamond1 1

University of Nebraska-Lincoln, Lincoln, NE, 2University of Nebraska Medical Center, Omaha, NE

1

University of Pennsylvania, Philaldelphia, PA

8:30AM

AKAP7γ Amplifies but Decelerates Localized PKA Signaling Kinetics E. Greenwald , M. Gildart , J. Saucerman , and K. Dodge-Kafka 1

1 3

2

1

3

University of Virginia, Charlottesville, VA, University of Saint Joseph, West Hartford, CT, University of Connecticut Health Center, Farmington, CT 2

8:45AM

The AXL Receptor is a Sensor of Ligand Spatial Heterogeneity A. Meyer1, C. Riley1, F. Gertler1, and D. Lauffenburger1 1

Massachusetts Institute of Technology, Cambridge, MA

9:00AM

Growth-differentiation Factor 11 (GDF11) as a Therapeutic Target in Basal-like Breast Cancers S. Bajikar1 and K. Janes1 1

University of Virginia, Charlottesville, VA

9:15AM

Systems Analysis of Cytokine Profiles Identifies Key Cellular Contributors to HIV Immune Response K. Arnold1, G. Szeto1, G. Alter2, D. Irvine1,2, and D. Lauffenburger1 Massachusetts Institute of Technology, Cambridge, MA, 2Ragon Institue of MGH, MIT and Harvard, Cambridge, MA

1

Stony Brook University, Stony Brook, NY, 2NYU School of Medicine, New York, NY

9:00AM

Imaging Metastasis Using a Targeted Nanoparticle and MRI E. Doolittle1, P. Peiris1, A. Abramowski1, R. Toy1, and E. Karathanasis1 Case Western Reserve University, Cleveland, OH

1

Track: Biomedical Imaging and Optics, Device Technologies and Biomedical Robotics OP-Fri-1-17 - Room 203A

Diagnostic Devices and Biosensors I Chairs: Jing Yong Ye, Mehmet Kaya 8:00AM

In Vivo Imaging of Wound Infection Using a Bacteria-targeting Optical Nanoprobe E. Tang1, A. Nair1, D. Baker1, W. Hu2, L. Tang1, and J. Zhou1 University of Texas at Arlington, Arlington, TX, 2Progenitec Inc., Arlington, TX

1

8:15AM

Noninvasive Frequency Domain Tissue Collagen Detection R. Liu1, Z. Zhao1, M. Zhou1, A. Argento1, Q. Fang2, and J. Lo1 University of Michigan at Dearborn, Dearborn, MI, 2McMaster University, Hamilton, Canada

1

8:30AM

Photoacoustic Spectroscopic Determination of Met-Hb Concentration Ratio Using an Open-Microcavity Photonic Crystal Ultrasound Sensor R. Peterson1, J. Ling2, C. Whitney1, and J. Ye1 The University of Texas at San Antonio, San Antonio, TX, 2Southwest Research Institute, San Antonio, TX

1

8:45AM

NutriPhone:Vitamin D Testing on Your Smartphone S. Lee1, S. Mehta1, and D. Erickson1 P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

130

BMES 2014

Cornell University, Ithaca, NY

1

8:00AM-9:30aM Platform Sessions Fri-1

2014 | october 24 | Friday

9:00AM

Fiber-Coupled Microcavity Probe for Label-Free Biosensing: A Demonstration with DNA Hybridization N. Leartprapun1, E. Toomey1, and J. Xu1 1

Brown University, Providence, RI

9:15AM

Handheld Spatial Frequency Domain Imaging System for Skin Imaging B. Yang1, J. Lesicko1, M. Sacks1, and J. Tunnell1 1

University of Texas at Austin, Austin, TX

Track: Biomechanics, Cellular and Molecular Bioengineering OP-Fri-1-18 - Room 203B

Cell-Cell Interactions and Intercellular Forces Chairs: Roland Kaunas, Leo Wan 8:00AM

Visualizing Mechanotransduction at Intercellular Junctions. D. Leckband1, T. Kim1, J. Sun1, I. Muhammed1, and Y. Wang2 1

SPECIAL SESSION

8:00 AM – 9:30 AM Convention Center, Room 204A

Whitaker International Program: Funding Opportunity for Young Biomedical Engineers The Whitaker International Program, founded in 2005 provides funding to emerging U.S.-based leaders in biomedical engineering to conduct a study and/or research project, with the underlying objective of building international bridges. Grant projects – including research, coursework, public policy work – are intended to enhance both the recipient’s career and the BME field. The goal of the Whitaker Program is to assist the development of professional leaders who are not only superb scientists, but who will advance the profession through an international outlook. The Whitaker Program has three sub-programs: Fellows and Scholars Program, Summer Program, and an Undergraduate Program. For more information, including program details, the online application and deadlines, visit: http://www.whitaker.org.

University of Illinois at Urbana, Urbana, IL, 2UC San Diego, La Jolla, CA

8:15AM

Protrusive Activity-dependent Inter-cellular Forces Determine Cell-cell Contact Stability V. Maruthamuthu1,2 and M. Gardel2 1

Old Dominion University, Norfolk, VA, 2University of Chicago, Chicago, IL

8:30AM

Intercellular Stresses Guide Endothelial Cell Polarization Under Laminar Fluid Shear Stress R. Steward Jr.1, D. Tambe1, and J. Fredberg1 1

Harvard University, Boston, MA

8:45AM

Cell-induced Nanoscale Displacements Reveal Localized, Autonomous Forces Exerted By Fibroblasts S. Knoll1 and T. Saif1 1

University of Illinois at Urbana-Champaign, Urbana, IL

9:00AM

Suspended Fused-Fiber Nanonets as Force Sensors A. Nain1 1

Virginia Tech, Blacksburg, VA

9:15AM

Finite Element Simulation of Valvular Interstitial Cells under Atomic Force Microscopy and Microindentation Experiments Y. Sakamoto1 and M. Sacks1 1

The University of Texas at Austin, Austin, TX

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131

Platform Sessions

Fri-1

Friday | October 24 | 2014

Platform Sessions Fri-2 1:45PM-2:45PM

FRIDAY, October 24, 2014 1:45 PM - 2:45 PM PLATFORM SESSIONS – Fri - 2

2:15PM

A Stretchable Microneedle Electrode Array for Electrical Muscle Stimulation G. Guvanasen1, A. Cheek1, R. Aguilar2, C. Shafor2, S. Rajaraman2, T. Nichols1, and S. DeWeerth1,3 Georgia Institute of Technology, Atlanta, GA, 2Axion BioSystems, Atlanta, GA, 3Emory University, Atlanta, GA

1

Track: Tissue Engineering, Stem Cell Engineering OP-Fri-2-1 - Room 001A

Epithelial and Adipose Tissue Engineering

2:30PM

Osseointegrated Prosthesis Mount with High-Channel-Count Peripheral Neural Interface Capability D. Kluger1, G. Clark1, D. Warren1, D. Hutchinson1, and K. Bachus1 1

University of Utah, Salt Lake City, UT

Chairs: George Pins, Piyush Koria 1:45PM

The Ups and Downs of 3D Skin Models: Engineering the Keratinocyte Microniche in vitro A. Clement1, T. Moutinho1, J. Molignano1, and G. Pins1 1

Worcester Polytechnic Institute, Worcester, MA

2:00PM

Platform Sessions

Fri-2

Track: Biomaterials, Tissue Engineering OP-Fri-2-3 - Room 006A

Biomaterial Scaffolds II Chairs: Jai Rudra, Mark Van Dyke 1:45PM

Elastin like Peptides (ELPs) Modulate Cellular Behavior through interaction with Cell Surface Glycosaminoglycans

In Vivo Assessment of Tissue Engineered Myocardial Patch for the Repair of Full-thickness RVOT Surgery

Y. Yuan1 and P. Koria1

S. Pok1 and J. Jacot1

1

University of South Florida, Tampa, FL

1

Rice University, Houston, TX

2:15PM

2:00PM

H. Wang1, B-X. Zhang1,2, L. Alan1, D. Dean1, M. Pilia3, A. Ong3, X-D. Chen1, and C-K. Yeh1,2

D. Munoz-Pinto1, A. Jimenez-Vergara1, T. Gharat1, and M. Hahn1

In Vitro Engineering of Functional Salivary Gland Cells Using Silk Fibroin Scaffolds UT Health Science Center at San Antonio, San Antonio, TX, 2GRECC & Research Service, South Texas Veterans Health Care System, San Antonio, TX, 3University of Texas at San Antonio, San Antonio, TX

Characterization of Sequential Collagen-Poly(ethylene glycol) Diacrylate Interpenetrating Networks for Vascular Tissue Engineering 1

Rensselaer Polytechnic Institute, Troy, NY

1

2:30PM

Phenotypic Characterization of Adipose Derived Stem Cells Differentiated Toward Urothelial Lineage J. Turner1, T. Matt1, and J. Nagatomi1 1

Clemson University, Clemson, SC

2:15PM

Enabling Surgical Placement of Hydrogels Through Achieving Paste-Like Rheological Behavior Prior to Crosslinking E. Beck1, B. Lohman1, S. Kieweg1, S. Gehrke1, C. Berkland1, and M. Detamore1 1

University of Kansas, Lawrence, KS

2:30PM

Thermoresponsive Nanonets for Improving Wound Healing in Diabetes Y. Zhu1, R. Hoshi1, and G. Ameer1

Track: Neural Engineering, Device Technologies and Biomedical Robotics OP-Fri-2-2 - Room 001B

Peripheral Neural Interfaces: Stimulation & Recording

1

Northwestern University, Evanston, IL

Track: Biomedical Engineering Education (BME) OP-Fri-2-4 - Room 006B

Design in BME Education

Chairs: Pamela VandeVord, Shyam Aravamudham

Chairs: Colin Drummond, Joe Tranquillo

1:45PM

1:45PM

S. Wendelken1, D. Page1, T. Davis1, H. Wark1, D. Warren1, R. Normann1, D. Hutchinson1, B. Greger2, and G. Clark1

G. Truskey1 and B. Barnes1

Partial Restoration of Sensorimotor Function After Hand Amputation Using Multiple Electrode Arrays 1

University of Utah, Salt Lake City, UT, 2Arizona State University, Tempe, AZ

2:00PM

Reestablishment of the blood nerve barrier in Regenerative Multielectrode Interfaces A. Kanneganti1, G. Bendale1, J. L Seifert1, V. Desai1, and M. Romero-ortega1 1

Univ. Of Texas at Arlington, Arlington, TX

A Program in Clinical Needs Finding, Medical Device Innovation and Design 1

Duke University, Durham, NC

2:00PM

Retrospective Analysis of Factors Impacting Senior Design Project Translation A. Sieving1, M. Pool2, A. Brightman1, and A. Rundell1 Purdue University, West Lafayette, IN, 2University of Illinois at Urbana-Champaign, Urbana, IL

1

2:15PM

The Teaching Dead J. La Belle1 and S. Maxwell1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

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Arizona State University, Tempe, AZ

1:45PM-2:45pm Platform Sessions Fri-2

2:30PM

Development of Design-Oriented BME Degree Programs In Nigeria M. Glucksberg1, A. Coker2, A. Osuntoki3, T. Douglas4, and R. Murphy5 Northwestern University, Evanston, IL, 2University of Ibadan, Ibadan, Nigeria, 3University of Lagos, Lagos, Nigeria, 4University of Cape Town, Cape Town, South Africa, 5Northwestern University, Chicago, IL

1

Novel Materials and Self Assembly Chairs: Robert Peattie, Mario Fabilli

Controlled Delivery of HB-EGF Accelerates Healing of Diabetic Wounds N. Johnson1,2 and Y. Wang1,2

P. Boyle1 and N. Trayanova1 1

Chairs: Shelly Peyton, Jennifer Munson

Tumor Metastasis At High Spatiotemporal Resolution: Examining Role Of Wnt Signalling In Colon Cancer V. Shirure1, M. Waterman1, and S. George1

2

2:00PM

Exploring the Synthesis, Self-Assembly, and Delivery of Concatameric siRNA-Polymer Nanoparticles K. Shopsowitz1, S. Morton1, E. Dreaden1, and P. Hammond1 MIT, Cambridge, MA

University of California, Irvine, Irvine, CA

2:00PM

Investigation of Paracrine Signaling in the Ovarian Cancer Microenvironment using a Novel Culture System M. Carroll1, L. Stopfer1, A. Desotell1, O. Velazquez1, and P. Kreeger1 1

University of Wisconsin, Madison, WI

2:15PM

2:15PM

Gap Junction Liposomes for Direct Therapeutic Delivery to the Cellular Cytoplasm A. Gadok , D. Busch , and J. Stachowiak 1

Johns Hopkins University, Baltimore, MD

Engineered Models of Cancer II

1

University of Pittsburgh, Pittsburgh, PA, McGowan Institute for Regenerative Medicine, Pittsburgh, PA

1

1

1

University of Texas at Austin, Austin, TX

2:30PM

Controlling the Single Wall Carbon Nanotube Dispersing Agent for Bioactive Molecule Delivery B. Holt1, P. Boyer1, K. Dahl1, and M. Islam1 1

Spatial Distribution of Light-Sensitive Cells Determines Effectiveness of Optogenetics-Based Termination of Atrial Arrhythmias

1:45PM

1:45PM

1

2:30PM

Track: Cancer Technologies OP-Fri-2-7 - Room 007A

Track: Drug Delivery OP-Fri-2-5 - Room 006C

1

2014 | october 24 | Friday

Carnegie Mellon University, Pittsburgh, PA

Track: New Frontiers and Special Topics, Translational Biomedical Engineering OP-Fri-2-6 - Room 006D

Bioelectronics Chairs: Ranu Jung, Tejal Desai 1:45PM

Taxol Resistance Exacerbates Ovarian Cancer Progression By Altering Adhesion Kinetics And Strength D. McGrail1, M. Qi1, K. Patel1, N. Khambhati1, and M. Dawson1 1

Georgia Institute of Technology, Atlanta, GA

2:30PM

Breast Cancer Cells Alter Nuclear Envelope Composition To Aid Migration Through Narrow Constrictions R. Gilbert1, C. Denais1, M. Krause2, K. Wolf2, and J. Lammerding1 Cornell University, Ithaca, NY, 2Radboud University Nijmegen Medical Center, Nijmegen, Netherlands

1

Track: Cardiovascular Engineering, Biomedical Imaging and Optics OP-Fri-2-8 - Room 007B

Cardiovascular Flow Imaging and Modeling in Health and Disease Chairs: W Robert Taylor, Hsiai Tzung

How Are We Galvanising The Interdisciplinary Research Community Into Developing High Precision Medicines That Target Peripheral Nerves?

1:45PM

K. Famm1

S. Hossain1, J. Zhang2, X. Fu2, G. Brunner3, J. Singh4, T. Hughes5, D. Shah4, and P. Decuzzi4

1

GSK, London, United Kingdom

2:00PM

Stimulation Design for the First Human Study of an Implanted Neurostimulator in Rheumatoid Arthritis Y. Levine1, A. Caravaca1, M. Faltys1, and R. Zitnik1 1

SetPoint Medical Corporation, Valencia, CA

2:15PM

Control of Ankle Movement by Stimulating with Longitudinal Intrafascicular Electrodes

MRI-based Computational Modeling of Blood Flow and Nanomedicine Depositionin Patients with Peripheral Arterial Disease Texas Heart Institute, Houston, TX, 2Carnegie Mellon University, Pittsburgh, PA, 3Baylor College of Medicine, Houston, TX, 4Houston Methodist Research Institute, Houston, TX, 5 The University of Texas at Austin, Austin, TX 1

2:00PM

Changing Vorticity in the Main Pulmonary Artery is Associated With RV-PA Decoupling in Pulmonary Hypertension V. Kheyfets1, J. Smyser2, A. Honeyman2, J. Browning3, J. Hertzberg3, J. Schroeder2, B. Fenster2, and R. Shandas1 1 3

University of Colorado Denver, Aurora, CO, 2National Jewish Health, Denver, CO, University of Colorado Boulder, Boulder, CO

A. Thota1, R. Siu1, S. Ganeswarathas2, L. Lykholt2, J. Abbas3, and R. Jung1 Florida International Univeristy, Miami, FL, 2Aalborg University, Aalborg, Denmark, 3Arizona State University, Tempe, AZ

1

BMES 2014

133

Platform Sessions

Fri-2

Friday | October 24 | 2014

Platform Sessions Fri-2 1:45PM-2:45PM

2:15PM

2:00PM

J. Hertzberg1, J. Browning1, B. Fenster2,3, and J. Schroeder2,3

C. Chen1, J. Koehler1, V. Yaldo 1, Z. Feng1, C. Zhou1, J. Cavanaugh1, and W. Chen2

Right Ventricular Diastolic Dysfunction and Vorticity In The Right Human Heart University of Colorado Boulder, Boulder, CO, 2National Jewish Health, Denver, CO, 3 University of Colorado Denver School of Medicine, Aurora, CO 1

2:30PM

Investigation of Spatio-Temporal Coupling Applied to Computational Models of Virtual Surgery A. Randles1,2, E. Draeger1, and F. Michor2

Track: Cellular and Molecular Bioengineering OP-Fri-2-9 - Room 007C

Molecular and Cell Engineering II Chairs: Evan Scott 1:45PM

PKA Controlled Regulation of SK Channel Expression Detected by Force Nanoscopy K. Abiraman1, A. Tzingounis1, and G. Lykotrafitis1

Fri-2

1

1

Interface Strength of a Percutaneous Prosthetic Attachment Implant G. Noble1, A. Litsky1, M. Allen1, N. Fitzpatrick2, and R. Hart1

2:30PM

Validation Of PVS Impression Molds For Profilometric Analysis Of Modular Joint Replacement Tapers K. Schwartzman1, P. Panigrahi1, and M. Harman1 1

Clemson University, Clemson, SC

Track: Nano to Micro Technologies, New Frontiers and Special Topics OP-Fri-2-11 - Room 008A

Diagnostics 1:45PM

2:00PM

Real-Time Imaging of Histone H3 Lysine 9 Tri-Methylation in Living Cells Q. Peng1,2, Y. Wang2, and Y. Wang1

Enhancing Diagnostic Assays via Stimuli-Responsive Reagents J. Lai1, S. Srinivasan1, I. Andrews1, B. Nehilla2, B. Lutz1, T. Schulte2, and P. Stayton1 1

University of California, San Diego, La Jolla, CA, 2Chongqing University, Chongqing, China, People's Republic of

1

2:15PM

Engineering an Integrin-Based, Chimeric Protein for Ligand-Regulated Binding J. Price , N. Carberry , C. Barnes , L. Pepper , and E. Boder 1

1

1

2

1

University of Tennessee, Knoxville, TN, 2Whitehead Institute for Biomedical Research, Cambridge, MA

2:30PM

Helix Insertion Drives Membrane Bending by Enabling Protein-Protein Crowding W. Snead , N. Momin , and J. Stachowiak 1

1

The University of Texas at Austin, Austin, TX

Track: Orthopaedic and Rehabilitation Engineering OP-Fri-2-10 - Room 007D

Rehabilitation Engineering: Prosthetics and Wearable Devices Chairs: Eric Perreault , David Lipps

University of Washington, Seattle, WA, 2Nexgenia Inc., Redmond, WA

2:15PM

Disease Detection by Ultrasensitive Quantification of Microdosed Synthetic Urinary Biomarkers A. Warren1, S. Gaylord2, K. Ngan2, M. Milutinovic2, G. Kwong1, S. Bhatia1, and D. Walt2 1

1

1

The Ohio State University, Columbus, OH, 2Fitzpatrick Referrals, Surrey, United Kingdom

Chairs: Tzahi Cohen-Karni , Lilie Grace Zhang

University of Connecticut, Storrs, CT

1

Wayne State University, Detroit, MI, 2Wayne State University, Grosse Pointe, MI

2:15PM

1

Lawrence Livermore National Laboratory, Livermore, CA, 2Dana-Farber Cancer Institute, Boston, MA

1

Platform Sessions

Structure Design and Algorism Strategy for Exoskeleton Powered Knee Devices

Massachusetts Institute of Technology, Cambridge, MA, 2Tufts University, Medford, MA

2:30PM

A Highly Sensitive Microsphere-Based Assay for Early Detection of Type I diabetes S. Bale1, G. Price1, M. Casali1, N. Saeidi1, A. Bhushan1, and M. Yarmush1 Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School and Shriners Burns Hospital, Boston, MA

1

Track: Tissue Engineering, Biomaterials OP-Fri-2-12 - Room 008B

Bone and Cartilage Tissue Engineering II Chairs: Kathryn Uhrich, Syam Nukavrapu 1:45PM

Enhanced Cartilage Formation In Vivo via Harnessing the Interplay Between Chondrocytes and Stem Cells J. Lai1, L. Deveza1, S. Yu1, S. Jeeawoody1, R. Smith2, W. Maloney2, and F. Yang1,2

1:45PM

Stanford University, Stanford, CA, 2Stanford School of Medicine, Stanford, CA

Generalizability of Control for a Powered Knee and Ankle Prosthesis on Level and Inclined Surfaces at User-Modulated Walking Speeds

1

N. Fey1,2, A. Simon1,2, and L. Hargrove1,2

Patient-Specific Auricular Cartilage Constructs Using High-Density Collagen for Ear Reconstruction

1

Rehabilitation Institute of Chicago, Chicago, IL, Northwestern University, Chicago, IL 2

2:00PM

B. Cohen1, R. Hooper2, J. Puetzer1, R. Nordberg1, A. Golas2, O. Asanbe2, K. Hernandez2, J. Spector2, and L. Bonassar1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

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BMES 2014

Cornell University, Ithaca, NY, 2Weill Cornell Medical College, New York, NY

1:45PM-2:45pm Platform Sessions Fri-2

2:15PM

2:30PM

D. Zhu1, X. Tong1, J. Lai1, and F. Yang1

C. Untaroiu1 and Y-C. Lu1

Mimicking Cartilage Tissue Zonal Organization by Engineering Hydrogels with Gradient Niche Cues 1

2014 | october 24 | Friday

Modeling Stretching and Tearing of Human Liver using Finite Element Optimization and Cohesive Zone Modeling Techniques

Stanford. University, Stanford, CA

1

Virginia Tech, Blacksburg, VA

2:30PM

Human Mesenchymal Stem Cell Spheroids in Fibrin Hydrogels Exhibit Improved Cell Survival and Potential for Bone Healing K. Murphy1 and J. Leach1 1

University of California, Davis, CA

Track: Bioinformatics, Computational and Systems Biology OP-Fri-2-15 - Room 202A

Systems Proteomics: Measurement and Computation

Track: Device Technologies and Biomedical Robotics OP-Fri-2-13 - Room 201

Chairs: Sriram Neelamegham, Christopher Barnes 1:45PM

Verification and Validation of Computational Models of Medical Devices

A Computational Platform to Analyze High Throughput Tandem Mass Spectrometry Based Glycoproteomics Experiments S. Neelamegham1, C. Lo1, J. Qu1, and G. Liu1 1

Chairs: Marc Horner, Dawn Bardot

State University of New York at Buffalo, Buffalo, NY

2:00PM

1:45PM INVITED

Identification of Novel Direct Kinase-Substrate Associations with Peptide Phosphorylation and Mass Spectrometry

D. Dragomir-Daescu1, S. Hodis1, and D. Kallmes1

C. Barnes1, A. Maiolica1, S. Wanka2, T. Schmidlin1, C. von Mering2, and R. Aebersold1

Modeling Hemodynamics in Patient Specific Intracranial Aneurysms 1

Mayo Clinic, Rochester, MN

1

2:15PM

Computational Fluid Dynamics Modeling Of The FDA Nozzle Using The V&V 20 Standard G. D'Souza , P. Hariharan , R. Malinauskas , R. Banerjee , and M. Horner 1

1 3

2

2

1

3

University of Cincinnati, Cincinnati, OH, 2Food and Drug Administration, Silver Spring, MD, ANSYS Inc., Evanston, IL

2:30PM

Identifying Uncertainties in Models and Experiments for Model Verification and Validation D. Riha1 1

Southwest Research Institute, San Antonio, TX

The Activation State Of The Breast Cancer Kinome: Characterization Of Subtypes And Identification Of Key Regulatory Kinases K. Collins1, T. Stuhlmiller1, T. Pham1, S. Angus1, J. Duncan1, M. Whittle1, L. Graves1, G. Johnson1,2, and S. Gomez1 1 University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Lineberger Comprehensive Cancer Center, Chapel Hill, NC

2:30PM

Improved Clustering of Molecular Measurements Using Ensemble Approaches K. Naegle1

Track: Biomechanics OP-Fri-2-14 - Room 103B

Impact and Injury Biomechanics Chairs: F. Scott Gayzik, Ruth Ochia

Astrocytic Thrombospondin-4 May Mediate Painful Facet Capsule Injury: Insights from In Vivo and In Vitro Studies N. Crosby1 and B. Winkelstein1 University of Pennsylvania, Philadelphia, PA

Track: Biomedical Imaging and Optics OP-Fri-2-16 - Room 202B

Magnetic Resonance Imaging II 1:45PM

Mapping Multiscale Myoarchitecture In Vivo With Generalized Q-Space MRI E. Taylor1 and R. Gilbert1 1

2:00PM

Morphological Changes in the Adult Skull with Age and Sex

J. Urban1,2, A. Weaver1,2, E. Lillie1,2, J. Maldjian2, C. Whitlow2,3, and J. Stitzel1,2 Virginia Tech - Wake Forest University, Winston Salem, NC, Wake Forest School of Medicine, Winston Salem, NC, 3Translational Science Institute, Wake Forest University, Winston Salem, NC 1

2

Northeastern University, Boston, MA

2:00PM

Biomimetic Neural Fiber MRI Phantom Exhibits Anomalous Diffusion A. Ye1, P. Hubbard Cristinacce2, F-L. Zhou2, Z. Yin1, G. Parker2, and R. Magin1 University of Illinois at Chicago, Chicago, IL, 2University of Manchester, Manchester, United Kingdom

1

2:15PM

2:15PM

Discrete Plasticity in Collagen Fibrils: Surprisingly Common in Unusual Places S. Veres1,2, B. Scott3, S. Wells3, and J. Lee3 3

Washington University in St Louis, St Louis, MO

Chairs: Mary McDougall, Omid Veiseh

1:45PM

1

Fri-2

ETH Zurich, Zurich, Switzerland, 2University of Zurich, Zurich, Switzerland

2:15PM

1

1

Platform Sessions

Saint Mary's University, Halifax, NS, Canada, Dalhousie University, Halifax, Canada, Dalhousie University, Halifax, NS, Canada 2

Developing Support Vector Machine Classification Of Associative Memory For Real-Time fMRI H. Deshpande1,2, A. Eklund2, J. Lisinski2, C. Mueller2, B. King-Casas1,2, and S. LaConte1,2 1

Virgnia Tech, Blacksburg, VA, 2Virgnia Tech Carilion Research Institute, Roanoke, VA

BMES 2014

135

Friday | October 24 | 2014

Platform Sessions Fri-2 1:45PM-2:45PM

2:30PM

Frequent Cognitive Activity for Non-demented Elderly Adults is Associated with Higher Brain Microstructural Integrity C. Barth1, R. Wilson2, A. Capuano2, S. Zhang2, D. Bennett2, and K. Arfanakis1,2 1

Illinois Institute of Technology, Chicago, IL, 2Rush University, Chicago, IL

Track: Biomedical Imaging and Optics, Device Technologies and Biomedical Robotics OP-Fri-2-17 - Room 203A

Diagnostic Devices and Biosensors II Chairs: Mahsa Ranji, Bilal Malik

Quantitative Mercury Sensing and Spatiotemporal Mapping Using a Smartphone Q. Wei1, R. Nagi1, K. Sadeghi1, S. Feng1, D. Tseng1, and A. Ozcan1 University of California, Los Angeles, Los Angeles, CA

2:00PM

Skin Cancer Detection with Diffuse Reflectance Spectroscopy R. Hennessy1, S. Maity1, S. Lim2, J. Tunnell1, and M. Markey1,3 The University of Texas at Austin, Austin, TX, University Health Network, Toronto, ON, Canada, 3The University of Texas MD Anderson Cancer Center, Houston, TX

1

2

2:15PM

Characterizing Perimeter Gated Single Photon Avalanche Diodes for Bioluminescence Applications M. Habib1 and N. McFarlane1 1

Computational Modeling of the Respiratory System Chairs: Sarah Vigmostad, Tilo Winkler 1:45PM

An Agent-Based Network Model of Pulmonary Fibrosis Development T. Wellman1, J. Bates2, G. Davis2, and B. Suki1 1

1:45PM

1

Track: Respiratory Bioengineering, Biomechanics OP-Fri-2-18 - Room 203B

University of Tennessee, Knoxville, TN

2:30PM

Boston University, Boston, MA, 2University of Vermont, Burlington, VT

2:00PM

Airway-Parenchymal Interactions During Heterogeneous Bronchoconstriction T. Winkler1 and R. Harris1 1

Massachusetts General Hospital and Harvard Medical School, Boston, MA

2:15PM

Comparison of Homogeneity and Efficiency of Surfactant Delivery into the Lung M. Filoche1 and J. Grotberg2,3 Ecole Polytechnique, Palaiseau, France, 2University of Michigan, Ann Arbor, MI, 3INSERM, Créteil, France

1

2:30PM

A Fully Resolved Glottal Flow Simulation In a Patient-specific Geometry of the Human Larynx M. farahani1, J. mousel1, S. Vigmostad1, and F. alipour1 1

The University of Iowa, Iowa City, IA

Shrink Wrap Multi-scale Silica Structures Used to Enhance Fluorescence Detection for DNA Microarrays H. Sharma1, J. Wood1, S. Lin1, R. Corn1, and M. Khine1 University of California, Irvine, Irvine, CA

1

SPECIAL SESSION

2:00 PM – 4:00PM Convention Center, Room 204A

Diversity, Health Disparities and Affordable Healthcare Chairs: Gilda Barabino, Cato Laurencin This session will be offered to better inform the broader BME community about health disparities and inequities and the role biomedical engineers can play in combating them. The session will provide a context for examining health disparities in translational research and will discuss historical examples of differential medical treatment and civil rights infringements based on race and ethnicity. Emphasis will be placed on achieving enhanced and affordable healthcare through engineering technologies. Moderator: Gilda Barabino, PhD, The City College of New York

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

136

BMES 2014

3:00PM - 4:00PM Platform Sessions Fri-3

FRIDAY, October 24, 2014

2014 | OCTOBER 24 | Friday

Track: Biomaterials OP-Fri-3-3 - Room 006A

3:00 PM - 4:00 PM PLATFORM SESSIONS – Fri - 3

Bioinspired and Self Assembling Biomaterials II

Track: Stem Cell Engineering, Cellular and Molecular Bioengineering OP-Fri-3-1 - Room 001A

Chairs: Michael Yu, Gargi Ghosh

Engineering Stem Cell Environments Chairs: Tara Deans, Leo Wan

3:00PM

Thromboresistant Collagen-mimetic Hydrogels as Coatings for Cardiovascular Devices V. Guiza-Arguello1, S. Becerra-Bayona1, S. Malmut1, B. Russell2, M. H??k2, E. Cosgriff-Hernandez3, and M. Hahn1

3:00PM

Incorporating Instructive Cues Within a Biomaterial to Engineer Hematopoietic Stem Cell Bioactivity

1 Rensselaer Polytechnic Institute, Troy, NY, 2Texas A&M Health Science Center, Houston, TX, 3Texas A&M University, College Station, TX

B. Mahadik1, S. Pedron1, L. Skertich1, and B. Harley1,2

3:15PM

University of Illinois at Urbana-Champaign, Urbana, IL, 2Institute for Genomic Biology, Urbana, IL

M. Cassin1, D. Susanti1, B. Mukhopadhyay1, and P. Rajagopalan1

1

The Design of Antimicrobial and Wound Healing Detachable Thin Films 1

3:15PM

Virginia Polytechnic Institute and State University, Blacksburg, VA

Development Of A Controlled Oxygen Delivery System To Increase Adipose Stem Cell Survival

3:30PM

D. Santiesteban1, A. Hannah1, L. Suggs1, and S. Emelianov1

C. Chesson1, R. Appavu1, and J. Rudra1

1

UT Austin, Austin, TX

Department of Pharmacology and Toxicology, Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX

1

3:30PM

Native Tissue-Specific ECMs Exhibit Distinct Mechanical Properties Affecting the Fate of hMSCs M. Marinkovic1, T. Block1, R. Rakian1, D. Dean1, M. Reilly1 and X-D. Chen1 1

Virus-inspired Self-assembling Peptide Nanoparticle Vaccines

University of Texas Health Science Center at San Antonio, San Antonio, TX

3:45PM

Collagen Mimetic Peptide Conjugated Nanoparticles For Targeting Denatured Collagens 1

3:45PM

Controlled Cell-Cell Interactions Enhance Functional Maturation of iPSC-Derived Human Hepatocytes D. Berger1, B. Ware1, M. Davidson1, and S. Khetani1 1

Colorado State University, Fort Collins, CO

University of Utah, Salt Lake, UT

Track: Neural Engineering OP-Fri-3-4 - Room 006B

Chairs: Erin Lavik, J-C Chiao

Neural Control and Modeling

3:00PM

Chairs: Katherine Steele, Eric Perreault

E. Lavik1

Hemostatic Nanoparticles: New Approaches for CNS Injuries 1

3:00PM

Stroke Reduces Neuromotor Control Bandwidth at the Elbow: A Pilot Study Marquette University, Milwaukee, WI, University of Wisconsin Oshkosh, Oshkosh, WI, Columbia University, New York, NY, 4Northwestern University, Evanston, IL 2

3:15PM

J. Mueller , A. Opitz , , W. Legon , A. Barbour , W. Bickel , W. Paulus , and W. Tyler1,2 1 3

2 3

2

2

2

3:30PM

Autaptic Connections Shift Network Excitability and Bursting L. Wiles1, D. Bassett1, and D. Meaney1 1

3

Virginia Tech, Blacksburg, VA, Virginia Tech Carilion Research Institute, Roanoke, VA, Georg-August-University, Gottingen, Germany 2

University of Pennsylvania, Philadelphia, PA

Conducting Polymer Films with Various Biomolecules for Cellular Adhesion and Growth S. Park1, G. Yang1, D. Nocera1, M. Abidian1, and S. Majd1 1

Pennsylvania State University, University Park, PA

3:30PM

Weak Electric Field Effects From Sham Transcranial Magnetic Stimulation on EEG Dynamics 1

Case Western Reserve University, Cleveland, OH

3:15PM

M. Bengtson1, L. Mrotek1,2, T. Stoeckmann1, C. Ghez3, and R. Scheidt1,4 3

Fri-3

Neural Engineering: Controlling Cell Behavior

Track: Neural Engineering OP-Fri-3-2 - Room 001B

1

Platform Sessions

B-H. San1, Y. Li1, and M. Yu1

Remote Regulation Of Neural Activity With Localized Release From Photo-sensitive Microgels W. Li1, R. Luo2, L. Yan3, A. Jadhav1, X. Chen3, C-H. Chen2, and P. Shi1 City University of Hong Kong, Kowloon, Hong Kong, 2National University of Singapore, Singapore, Singapore, 3Cityu University of Hong Kong, Kowloon, Hong Kong

1

3:45PM

Quercetin And Derivatives Reduce Nuclear Factor-κB Activation Associated With Alzheimer's Disease K. Pate1, M. Rogers1, J. Clegg1, and M. Moss1 1

University of South Carolina, Columbia, SC

3:45PM

Linear Decoders of Retinal Spike-trains Yield Ideal-Observer Performance for Broad Classes of Visual Tasks A. Iyer1 and N. Grzywacz1 1

University of Southern California, Los Angeles, CA

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137

Friday | OCTOBER 24 | 2014

Platform Sessions Fri-3 3:00PM - 4:00PM

Track: Drug Delivery OP-Fri-3-5 - Room 006C

Multifunctional Drug Delivery Chairs: Lola Eniola-Adefeso,YongTae Kim

Imaging Strategies in Cancer

3:00PM

Chairs: Javier Jo,Vikram Kodibagkar

In Vivo Delivery of Transcription Factors by Multifunctional Oligonucleotides Suppress Liver Failure M. Rafi1, K. Lee1, X. Feng1, R. Tang1, N. Lingampalli1, and N. Murthy1 1

University of California Berkeley, Berkeley, CA

3:15PM

Bioengineered Nanoporous Silicon with Leukocyte Membrane Promotes Endothelial Adhesion M. Evangelopoulos1, R. Palomba1, C. Corbo1, A. Parodi1, S. Acciardo1, and E. Tasciotti1 Houston Methodist Research Institute, Houston, TX

1

3:30PM

Light-activated Collapse of Sub-micron Gold Nanoplate/Polymer Shell Composite Particles for Drug Delivery Applications M. O'Toole1, K. James1, D. Patel2, and R. Keynton1 University of Louisville, Louisville, KY, 2Energy Delivery Solutions, Jefersonville, IN

1

3:45PM

Controlled Delivery of an Anticonvulsant Drug Pregabalin Through Visible-Light-Cured pH Responsive Composite Hydrogels Platform Sessions

Fri-3

Track: Cancer Technologies, Biomedical Imaging and Optics OP-Fri-3-7 - Room 007A

S. Kizilel1, O. Cevik1, and D. GidonI1 1

3:00PM

Down to 200 Cancer Cells Detected in Tumor-Draining Lymph Nodes by Dual-Tracer Fluorescence Imaging K. Tichauer1, K. Samkoe2, J. Gunn2, S. Kanick2, P. Hoopes2, R. Barth2, P. Kaufman2, T. Hasan3, and B. Pogue2 Illinois Institute of Technology, Chicago, IL, 2Dartmouth College, Hanover, NH, Massachusetts General Hospital, Boston, MA

1 3

3:15PM

Multicolor Three-Dimensional Tracking of Single Epidermal Growth Factor Receptors Y-L. Liu1, E. Perillo1, C. Liu1, Y-A. Chen1, M-C. Hung2,3,4, A. Dunn1, and H-C. Yeh1 Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 3Graduate School of Biomedical Sciences at Houston, The University of Texas, Houston, TX, 4Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University, Taichung, Taiwan

1 2

3:30PM

Image-guided Photodynamic Therapy and Irinotecan Chemotherapy Combination for Pancreatic Cancer Treatment S. Mallidi1, H-C. Huang1, C-T. Chiang1, Z. Mai1, I. Rizvi1, and T. Hasan1 1

KOC University, Istanbul, Turkey

Harvard Medical School, Boston, MA

3:45PM

Track: Translational Biomedical Engineering, Stem Cell Engineering OP-Fri-3-6 - Room 006D

Translational Therapeutics for Regenerative Medicine Chairs: Robert Mauck, Mark Van Dyke 3:00PM

Injection of Matrilin-3/Nanotube Matrix for Treatment of Growth Plate Cartilage Injury in Vivo Y. Chen1, P. McClure1, S. McAllister1, T. Albright1, H. Yu1, L. Eric1, D. Moore1, H. Fenniri2, M. Ehrlich1, and Q. Chen1 1

Brown University, Providence, RI, 2Northeastern University, Boston, MA

3:15PM

The Story of Hepregen Corporation: Bringing Engineered Liver Devices to the Marketplace S. Khetani1 1

Colorado State University, Fort Collins, CO

3:30PM

Glypisomes: A Novel Construct for Enhancing of Growth Factor Activity for Therapeutic Angiogenesis A. Monteforte1, B. Lam1, A. Dunn1, and A. Baker1 1

University of Texas at Austin, Austin, TX

3:45PM

Exogenous Nitric Oxide Production Using Dielectric Barrier Discharge Plasma for Enhanced Osteoblasts Activity M. Elsaadany1, G. Subramanian1, H. Ayan1, and E. Yildirim-Ayan1,2 1

University of Toledo, Toledo, OH, 2University of Toledo Medical Center, Toledo, OH

P = Poster Session P = Poster Session OP = Oral Presentation OP = Oral Presentation = Reviewer Choice Award

)

138

BMES 2014

Design of Biofunctionalized Rare-Earth Albumin Nanocomposites for Tumor Microlesion Detection and Tracking M. Zevon1, V. Ganapathy1, P. Kim1, D. Naczynski2, M-C. Tan3, R. Riman1, C. Roth1, and P. Moghe1 Rutgers University, Piscataway, NJ, 2Stanford University, Stanford, CA, 3Singapore University of Technology and Design, Singapore, Singapore

1

Track: Cardiovascular Engineering OP-Fri-3-8 - Room 007B

Structure-function Relationship in the Cardiovascular System Chairs: Manu Platt, Michael Davis 3:00PM

An In Vitro Study of the Effect of the Craya-Curtet Number on Contrast Injections during Angiography A. Pagano1, C. Sadasivan1, D. Fiorella1, H. Woo1, and B. Lieber1 1

Stony Brook University, Stony Brook, NY

3:15PM

Quantifying Myocardial Structure and Function Following Infarction Through Multiphoton Microscopy K. Quinn1, K. Sullivan1, Z. Ballard1, I. Georgakoudi1, and L. Black1,2 1

Tufts University, Medford, MA, 2Tufts University School of Medicine, Boston, MA

3:30PM

Myoarchitectural Differences Between the Right and Left Ventricles of the Mouse Heart Determined by Generalized Q-space (GQ) MRI E. Taylor1, S. Mijailovich1, A. Abrishamchi1, M. Hoffman1, and R. Gilbert1 1

Northeastern University, Boston, MA

3:00PM - 4:00PM Platform Sessions Fri-3

2014 | OCTOBER 24 | Friday

3:45PM

3:45PM

R. Dholakia1, C. Sadasivan1, L. Peeling1, D. Fiorella1, H. Woo1, and B. Lieber1

E. Garibay1, M. Milewski1, S. Ounpuu1, J. Woods1, N. Giampetruzzi1, and D. Suprenant1

The Influence of Input Variables on Size Outcome in the Rabbit Elastase-Induced Aneurysm Model 1

Stony Brook University, Stony Brook, NY

Knee Biomechanics of Adolescent Athletes Returning to Sports Following ACL Reconstruction 1

Track: Cellular and Molecular Bioengineering OP-Fri-3-9 - Room 007C

Cell Motility Chairs: William Guilford, Cynthia Reinhart-King 3:00PM

Equations of Inter-doublet Separation during Flagella Motion Explain Propagation of Dynein Activity P. Bayly1 and K. Wilson1

Connecticut Children's Medical Center, Farmington, CT

Track: Nano to Micro Technologies OP-Fri-3-11 - Room 008A

Nanoparticles and Theranostics Chairs: Carlos Rinaldi, Hyun Joon Kong 3:00PM

Facile Method for the Site-Specific, Covalent Attachment of Full-Length IgG onto Nanoparticles J. Hui1 and A. Tsourkas1

Washington University in Saint Louis, Saint Louis, MO

1

1

3:15PM

The Motile System Of A Parasite Measured In Live Cells At The Level Of Single Molecules R. Stadler1, L. White1, K. Hu2, B. Helmke1, and W. Guilford1 University of Virginia, Charlottesville, VA, 2Indiana University, Bloomington, IN 

1

University of Pennsylvania, Philadelphia, PA

3:15PM

New Design Strategies for Multicolor NanoCluster Beacons J. Obliosca1, M. Babin1, C. Liu1, Y-L. Liu1, R. Batson1, and H-C. Yeh1 1

University of Texas at Austin, Austin, TX

3:30PM

3:30PM

C. Paul1,2,3, M. Mahoney1, and K. Konstantopoulos1,2,3,4

Y. Kang1, H. Wostein1, and S. Majd1

Dimensionality and Contact Guidance Affect Tumor Cell Migration and Decision Making Johns Hopkins University, Baltimore, MD, 2Institute for NanoBioTechnology, Baltimore, MD, 3Physical Science-Oncology Center, Baltimore, MD, 4Center of Cancer Nanotechnology Excellence, Baltimore, MD

1

3:45PM

Filling the Gap: Relative Role of Proliferation versus Migration in Response to Injury of Vascular Endothelial and Smooth Muscle Cells K. Ammann , K. DeCook , P. Tran , and M. Slepian 1

1

1

A New Methodology for Preparation of Uniformly Sized Cell Membrane Mimicking Vesicles 1

Pennsylvania State University, University Park, PA

Platform Sessions

3:45PM

A Multifunctional Nanoplatform for the Enhancement and Prediction of Therapeutic Response to External Beam Radiation Therapy A. Al Zaki , C. McQuade , G. Kao , J. Dorsey , and A. Tsourkas 1

1

1

1

1

1

1

University of Pennsylvania, Philadelphia, PA

University of Arizona, Tucson, AZ

1

Track: Orthopaedic and Rehabilitation Engineering, Biomechanics OP-Fri-3-10 - Room 007D

Translational Research Relevant to Common Orthopaedic Injuries

Track: Tissue Engineering, Biomaterials OP-Fri-3-12 - Room 008B

Scaffolds and Surfaces for Tissue Engineering III Chairs: Taby Ahsan, Sheila Grant 3:00PM

Chairs: F. Scott Gayzik, Grace O'Connell

Mechanical Properties Of Decellularized Lung Extracellular Matrix Tissue Scaffold Electospun With PLLA

3:00PM

B. Blakeney1, G. Schreyack1, R. Pouliot1, and R. Heise1

Epimuscular Fat in the Human Rotator Cuff is a Novel Brown Fat Depot Influenced by Cuff State G. Meyer1, M. Gibbons2, E. Sato2, J. Lane2, S. Ward2, and A. Engler2 1

Washington University in St. Louis, St. Louis, MO, 2UCSD, La Jolla, CA

3:15PM

The Effect of Size and Location of Tears in the Supraspinatus Tendon on Potential Tear Propagation S. Damle1, J. Thunes1, S. Pal1, R. Miller1, R. Debski1, and S. Maiti1 1

University of Pittsburgh, Pittsburgh, PA

3:30PM

1

Virginia Commonwealth University, Richmond, VA

3:15PM

Electrochemically Compacted Collagen Matrices for Corneal Repair R. Iyer1 and V. Kishore1 1

Florida Institute of Technology, Melbourne, FL

3:30PM

Bundled Gel Fibers Fabricated with a Combination of Microfluidic Device and Phase-Separated Polymer Solution Y. Matsunaga1 and Y-J. Kim1 1

The University of Tokyo, Tokyo, Japan

Surgical Design and Graft-Tunnel Interaction: An Analytical examination of ACL reconstruction S. Salehghaffari1 and Y. dhaher1 Northwestern University, Chicago, IL

1

BMES 2014

139

Fri-3

Friday | OCTOBER 24 | 2014

Platform Sessions Fri-3 3:00PM - 4:00PM

3:45PM

3:45PM

J. Coburn1, B. Marelli1, F. Omenetto1, and D. Kaplan1

R. Chung1, M. Niemiera1, A. Ritter1, T. Errico2, and A. Valdevit1,2

Tailoring Silk Fibroin Degradation using Embedded Proteolytic Enzymes 1

Tufts University, Medford, MA

Track: Bioinformatics, Computational and Systems Biology OP-Fri-3-15 - Room 202A

Biomedical Robotics

Prokaryotic Systems Biology

Chairs: Arthur Ritter, Jaydip Desai

Chairs: Ranjan Srivastava, Cheemeng Tan

3:00PM

3:00PM

C. Bryson1, A. Orekhov1, and D. Rucker1

J. Bartell1, J. Thøgersen2, J. Thykær2, K. Nielsen2, S. Molin2, L. Jelsbak2, and J. Papin1

1

University of Tennessee, Knoxville, TN

3:15PM

3D Printed Optogenetic Skeletal Muscle-Powered Biological Machines R. Raman1, C. Cvetkovic1, B. Williams1, S. Uzel2, R. Platt2, R. Kamm2, M. Saif1, and R. Bashir1

Comparative Systems Analysis Of Persistent Cystic Fibrosis Pathogens University of Virginia, Charlottesville, VA, 2Technical University of Denmark, Lyngby, Denmark

1

3:15PM

In Silico Analysis of Bacillus Anthracis Predicts Link Between Quorum Sensing Circuit And Iron Metabolism

University of Illinois at Urbana-Champaign, Champaign, IL, 2Massachusetts Institute of Technology, Cambridge, MA

E. Bautista1 and R. Srivastava1

3:30PM

3:30PM

Z. Su1 and G. Loeb1,2

J. Bartell1, A. Blazier1, P. Yen1, J. Thøgersen2, P. Jensen3, and J. Papin1

1

Haptic Robot and Human Ppsychophysical Studies: A Complementary Framework to Decode Haptic Perception

Fri-3

Stevens Institute of Technology, Hoboken, NJ, 2NYU Langone Medical Center, New York, NY

1

Track: Device Technologies and Biomedical Robotics OP-Fri-3-13 - Room 201

Design of a Compact Manipulator with Six Degrees-of-Freedom for Flexible Access Surgery

Platform Sessions

Trabecular Bone Response to Elevated Loading Frequencies

1

University of Southern California, Los Angeles, CA, 2Syntouch LLC, Los Angeles, CA

3:45PM

Portable Robot for Autonomous Venipuncture using 3D Near Infrared and Ultrasound Guidance A. Chen1, M. Balter1, and T. Maguire1 1

Rutgers University, Piscataway, NJ

Track: Biomechanics OP-Fri-3-14 - Room 103B

Countermeasures for Bone Loss and Injury Chairs: Russell Main, Oran Kennedy 3:00PM

Early Axial Compressive Loading Delays Mineralization and Remodeling of a Tibial Cortical Defect in Mice R. Carrera1, D. Wagner2, B. George3, P. Leucht3, D. Hunter3, J. Helms3, G. Beaupre2, and A. Castillo2,3 Stanford University, Palo Alto, CA, 2VAPAHCS, Palo Alto, CA, 3Stanford University School of Medicine, Palo Alto, CA

1

3:15PM

Photoacoustic Stimulation Enhances Bone Fracture Healing in Rats Y. Talukdar1, J. Rashkow1, S. Patel1, G. Lalwani1, and B. Sitharaman1 1

Stony Brook University, Stony Brook, NY

3:30PM

Both Bone Quality and Quantity of Obese Mice are Enhanced by Low Intensity Vibrations B. Nguyen1, M. Chan1, L. Lin1, Y-X. Qin1, and C. Rubin1 1

Stony Brook University, Stony Brook, NY

P = Poster Session P = Poster Session OP = Oral Presentation OP = Oral Presentation = Reviewer Choice Award

)

140

BMES 2014

1

University of Connecticut, Storrs, CT

Systems Analysis of Pseudomonas aeruginosa to Identify Drug Targets and Virulence Factor Dependencies University of Virginia, Charlottesville, VA, 2Technical University of Denmark, Lyngby, Denmark, 3Boston College, Chestnut Hill, MA

1

3:45PM

Phenotypic Signatures Arising from Unbalanced Bacterial Growth C. Tan1, R. Smith2, M-C. Tsai3, R. Schwartz3, and L. You4 1 3

University of California Davis, Davis, CA, 2Nova Southwestern, Fort Lauderdale, FL, Carnegie Mellon University, Pittsburgh, PA, 4Duke University, Durham, NC



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337

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260 259 241 242

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180 179 161 162

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120 119 101 102

99 82

79 62

59 42

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19 2

100 81

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60 41

40 21

20 1

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275 274 266 267

295 294 286 287 273 268

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152 151 149 150

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252 251 249 250

135 134 126 127

115 114 106 107

96 85

95 86

94 87

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18 3

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37 24

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35 26

55 46

75 66

14 7

34 27

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74 67

13 8

33 28

53 48

73 68

CELL BEHAVIOR

97 84

CONTROLLING

117 116 104 105

AND

137 136 124 125

12 9

32 29

52 49

72 69

92 89

11 10

31 30

51 50

71 70

91 90

112 111 109 110

132 131 129 130

MICRO ENVIRONMENTS

157 156 144 145

175 174 166 167

195 194 186 187

215 214 206 207

BIOMATERIALS,

177 176 164 165

197 196 184 185

217 216 204 205

SYNTHETIC BIOLOGY

237 236 224 225

AND

257 256 244 245

TISSUE ENGINEERING

278 263

280 279 261 262

297 296 284 285

TRANSLATION,

298 283

300 259 281 282

REFRESHMENT BREAKS

P O S T E R S

454 447

453 452 448 449

465 464 460 461

477 476 472 473

DRUG

466 459

478 471

394 387

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405 404 400 401

417 416 412 413

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333 332 328 329

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331 330

343 342

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367 366

379 378

NEURAL ENG’G 312 311 301 302

324 323 313 314

336 335 325 326

346 339

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382 375

IMAGING 348 347 337 338

360 359 349 350

372 371 361 362

384 383 373 374

ENGINEERING

396 395 385 386

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463 462

475 474

CARDIOVASCULOR

408 407 397 398

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DELIVERY

456 455 445 446

468 467 457 458

480 479 469 470

REFRESHMENT BREAKS

FRIDAY

P O S T E R S

676 66

662 653

648 639 635 625 620 611

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592 583

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564 555

550 545 540 531 526 517 512 503

678 677 665 66 664 663 651 652 650 649 637 638 636 635 623 624 622 621 609 610

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BIOMECHANICS

577 576 570 571

ORTHOPAEDIC

591 590 584 585

AND

605 604 598 599

CARDIOPULMONARY

619 618 612 613

633 635 626 627

647 646 640 641

661 660 654 655

TECHNOLOGY

675 674 668 669

MICRO

686 681

688 687 679 680

699 698 692 693

NANO

700 691

702 701 689 690

REFRESHMENT BREAKS

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-30 Assessing the Biological Activity of an Ester-modified, Self-assembling RGD Peptide as the Basis for Highly Degradable, Cell-instructive Hydrogel Biomaterials

FRIDAY, October 24, 2014 9:30 AM - 5:00 PM POSTER SESSIONS

K. Eckes1, C. Laramy1, M. Ruehle1, and L. Suggs1 1

Biomaterials, Microenvironments and Controlling Cell Behavior: P-Fri-1 to P-Fri-208

P-Fri-31 Bioinspired Tannin Complexes for Redox Responsive Biomaterials

Translation, Tissue Engineering and Synthetic Biology: P-Fri-211 to P-Fri-290

P-Fri-32 Novel Free Form Fabrication Using a Modified, Thermo-reversible, Type-I Collagen

H. Cheng1, C. Drinnan1, M. MacPherson1, and O. Fisher1 1

Neural Engineering: P-Fri-301 to P-Fri-328

Rutgers University, Piscataway, NJ

P-Fri-33 Self-assembly of Individual Cyclic Peptide Nanotubes (ICPNs) for In Vivo Sensing

Imaging: P-Fri-329 to P-Fri-365

L. Sun1, Y. Wang1, Y. Huang1, and M. Zhang1 1

The Ohio State University, Columbus, OH

P-Fri-34 The Effect of L-Arginine on Platelet Adhesion using Bovine Whole Blood on a Novel Biointerface: d-LbL

Cardiovascular Bioengineering: P-Fri-366 to P-Fri-409

R. Porter1, J. Adangai1, and M. Watson1

Drug Delivery: P-Fri-410 to P-Fri-473

Fri

Temple University, Philadelphia, PA

K. Drzewiecki1, W. Ko1, A. Chavkin1, D. Giordano1, and D. Shreiber1 1

Poster Session

The University of Texas at Austin, Austin, TX

1

LeTourneau University, Longview, TX

P-Fri-35 Hydrogen Peroxide Generation and Cytotoxicity of Hydrogel-bound Mussel Inspired Adhesives

Cardiopulmonary and Orthopaedic Biomechanics: P-Fri-501 to P-Fri-645

H. Meng1 and B. Lee1 1

Michigan Technological University, Houghton, MI

P-Fri-36 Targeted Delivery of SV40 Virus-Like Particles for Vaccine Vehicles

Nano and Micro Technology: P-Fri-651 to P-Fri-701

M-C. Hsieh1 and M. Pishko1 1

Texas A&M University, College Station, TX

Track: Biomaterials

Track: Biomaterials

Bioinspired and Self Assembling Biomaterials

Biomaterial Scaffolds Chairs: Vassilios Sikacitsas, Daniel Alge

Chairs: Meng Deng, Wei Li P-Fri-27 Mechanical Flows Govern the Architecture of Actin Bundle Structures S. Jo1 and H. Lee1 1

R. Phanse1, M. Fabiilli1, A. Moncion1, J. Fowlkes1, and R. Franceschi1

Yonsei University, Seoul, Korea, Republic of

1

P-Fri-28 Polydopamine-coated Implantable Metallic Seed for Migration Prevention W. Lee , H. Lee , M. Park , C. Park , J. Park , S-J. Ye , and Y. Choy 1

1

1

1

1

2

3

Seoul National University, Seoul, Korea, Republic of, 2Seoul National University Hospital, Seoul, Korea, Republic of, 3Seoul National University College of Medicine, Seoul, Korea, Republic of

1

P-Fri-29 Bio-inspired Functional Collagen-Cellulose Hydrogel Nanocompositeas a Potential Scaffold in Cardiovascular Tissue Engineering P. Pooyan , R. Tannenbaum , and H. Garmestani 1

1

1

Georgia Institute of Technology, Atlanta, GA

)

P-Fri-89 Increasing Scaffold Attenuation with Hydroxyapatite Enhances an Ultrasound-induced Gene Switch

1

University of Michigan, Ann Arbor, MI

P-Fri-90 Porated PDMSstar-PEG Hydrogels for Osteochondral Tissue Engineering R. Sehnert1, E. Gacasan1, B. Basagaoglu1, B. Bailey1, and M. Grunlan1 1

Texas A&M University, College Station, TX

P-Fri-91 Electrospinning Silk With Selenium Nanoparticles For Antibacterial Skin Applications S. Chung1, M. Stolzoff1, B. Ercan1, and T. Webster1 Northeastern University, Boston, MA

1

P-Fri-92 Development of Gel Injectable Matrix for Treatment of Muscle Degeneration K. Wilson1 and J. Wolchok1 University of Arkansas, Fayetteville, AR

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

142

BMES 2014

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-93 In Vitro Investigation of a Novel Genipin-Nanoparticle-Collagen Template

P-Fri-105 Electrospinning of Arabinoxylan as a Novel Nanofiber Scaffold

Z. Beach1, J. Bradley1, D. Grant1, and S. Grant1

D. Aduba, Jr.1, W. Yeudall1, and H. Yang1

1

1

University of Missouri, Columbia, MO

P-Fri-94 Characterization of a Nanomaterial-Tissue Patch for Vascular and Cardiac Reconstruction A. Ostdiek1, R. Gopaldas2, and S. Grant1 1

University of Missouri, Columbia, MO, 2Prairie Cardiovascular, Springfield, IL

P-Fri-95 Self-Fitting Shape Memory Polymer Scaffolds For Bone Defect Repair L. Nail1, D. Zhang1, K. Peterson1, O. George1, J. Reinhard1, H. Glidewell1, and M. Grunlan1 1

Texas A&M University, College Station, TX

P-Fri-96 Characterizing the Cellular Response of Electrospun Manuka Honey-eluting Scaffolds B. Minden-Birkenmaier1, E. Growney Kalaf1, R. Flores1, B. Janowiak1, and S. Sell2 1

Saint Louis University, St. Louis, MO, 2Saint Louis University, St Louis, MO

P-Fri-97 Characterization Of Pullulan As A Novel Material For Peripheral Nerve Conduits J. Simmons1, Z. Snow1, M. Grinter1, and P. VandeVord1 1

C. Peak1, S. Nagar1, R. Watts1, and G. Schmidt1

J. Grasman1, R. Page1, T. Dominko1, and G. Pins1

Federal University of ABC, Santo Andre, Brazil, 2INCT-Biofabris, Campinas, Brazil, Mechanical Engineering - State University of Campinas, Campinas, Brazil

P-Fri-101 Functional Lymphatics That Drain Collagen-Based Scaffolds R. Thompson1, B. Coisman1, and J. Tien1 1

Boston University, Boston, MA

K. White , C. Franco , J. West , and R. Olabisi 2

3

1

P-Fri-103 Raw Material-Directed Differentiation Of Rat Bone Marrow Stromal Cells In Microsphere Based Gradient Scaffolds V. Gupta1 and M. Detamore1

1

Stevens Institute of Technology, Hoboken, NJ

P-Fri-108 Development of PLLA Hollow Fiber Scaffold by Electrospinning for Cartilage Regeneration K. Minamimoto1, Y. Morita1, T. Katayama1, and E. Nakamachi1 1

Doshisha University, Kyotanabe, Japan

P-Fri-109 Gelatin Foam Production: In Vitro Test L. Rodrigues1,2, D. Ferraraz1, M. Nascimento1, and C. Lombello1 1

Federal University of ABC - UFABC, Santo Andre, Brazil, 2INCT-BioFabris, Campinas, Brazil

Biomaterials Design Chairs: Hitesh Handa, Michael Fenn P-Fri-13 Stiffness Enhancement of Ultra-flexible Implantable Microsensor Array with Biodegradable Materials C. Nguyen1, L. Lee1, S. Rao1, and J-C. Chiao1 1

University of Texas at Arlington, Arlington, TX

1 Wake Forest University-Virginia Tech, Winston-Salem, NC, 2Wake Forest Baptist Hospital, Winston-Salem, NC

P-Fri-15 Water Structure in Hydrated Poly(2-methoxyethyl acrylate) Analogues Possessing Blood Compatibility 1

Yamagata University, Yonezawa, Japan

P-Fri-16 The Role of Substrate Materials in Controlled Culture of Endothelial Cells 1

E. Alpaslan1 and T. Webster1 1

D. Bhuiyan1, J. Middleton1, R. Tannenbaum2, and T. Wick1

University of Houston, Houston, TX

P-Fri-17 Iron Oxide and Selenium Nanoparticles Combined with Methotrexate to Inhibit Bone Cancer Growth

University of Kansas, Lawrence, KS

P-Fri-104 Fabrication of Biodegradable hydroxyapatite-PLGA-collagen Biomaterial for Bone Regeneration

Norheastern University, Boston, MA

P-Fri-18 Reduction Induced Biodegradable Polyurethane Elastomers for Biomedical Applications C. Xu1,2 and Y. Hong1,2 University of Texas at Arlington, Arlington, TX, 2The University of Texas Southwestern Medical Center at Dallas, Dallas, TX

1

University of Alabama at Birmingham, Birmingham, AL, 2Stony Brook University, Stony Brook, NY

1

C. Maglaras1, A. Ritter1, D. Kalyon1, A. Ergun-Butros1, and A. Valdevit1

W. Wosik1, S. Das1, Z. Zuo1, and F. Merchant1

Rutgers University, Piscataway, NJ, 2Twister Biotech, Houston, TX, 3Duke University, Durham, NC 1

1

P-Fri-107 Response of Hydroxyapatite and Tricalcium Phosphate Bone Scaffolds to Elevated Loading Frequencies

K. Sato1, S. Kobayashi1, T. Hoshiba1, S. Watahiki1, M. Oikawa1, and M. Tanaka1

P-Fri-102 Directing Bone Formation Using Nacre Proteins Patterned on Poly(ethylene glycol) Substrates 1

Stony Brook University, Stony Brook, NY

H. Warner1,2, R. Wang1,2, J. Jordan2, M. Morykwas1,2, L. Argenta2, and W. Wagner1,2

L. Rodrigues1,2, C. Zavaglia2,3, and C. Lombello1 3

1

P-Fri-14 Biodegradable Sponge Fabrication For Use In Negative Pressure Wound Therapy

Worcester Polytechnic Institute, Worcester, MA

P-Fri-100 Scaffold HA/TCP Coated by Gelatin: In Vitro Test 1

B. Farshid 1, G. Lalwani1, and B. Sitharaman1

)

Purdue University, West Lafayette, IN

P-Fri-99 Stimulating Cell Recruitment on Fibrin Microthreads to Enhance Skeletal Muscle Regeneration 1

P-Fri-106 Cytotoxicity of Boron Nitride Reinforced Polymeric Scaffolds.

Track: Biomaterials

Virginia Polytechnic Institute and State University, Blacksburg, VA

P-Fri-98 Degradable and Semi-Interpenetrating Hydrogels from PEG and Collagen for Tissue Scaffolds 1

Virginia Commonwealth University, Richmond, VA

See page 141 for Poster floor plan

BMES 2014

143

Poster Session

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-19 Enhanced Protein Resistance of Silicones Containing PEG-silane Amphiphiles as Surface Modifying Additives

P-Fri-138 Patterning Cellular Microenvironments with a Hybrid Photopatterned Enzymatic Reaction (HyPER) Cell-compatible Platform

M. Rufin1, J. Gruetzner1, M. Hurley1, M. Hawkins1, E. Raymond1, J. Raymond1, and M. Grunlan1

D. Griffin1, N. Darling1, and T. Segura1

1

Texas A&M University, College Station, TX

P-Fri-20 Electrosprayed Polyethylene Glycol Hydrogel Microspheres for Platelet Rich Plasma Delivery in Knee Osteoarthritis E. Jain1, K. Scott1, S. Sheth1, S. Zustiak1, and S. Sell1 1

Saint Louis University, St. Louis, MO

P-Fri-21 Spun Silk-Fibronectin Protein Alloy Fibers for Improved Cellular Adhesion M. Jacobsen1, D. Li1, N. Rim1, N. Hall1, M. Smith1, and J. Wong1 1

Boston University, Boston, MA

P-Fri-22 Polycaprolactone Nanofibrous Materials as an Efficient Dry Eye Test Strip K. Patel1, V. Kandala2, A. Aphale2, and P. Patra2 1

University of Bridgeport, bridgeport, CT, 2University of Bridgeport, Bridgeport, CT

P-Fri-23 Manipulation of Hydrogel Structure Using the Mechanical Flow Induced by Surface Acoustic Wave B. Kang1, S. Jo1, Y. Jeon1, and H. Lee1 1

Yonsei University, Seoul, Korea, Republic of

P-Fri-24 Influence of Gallium Incorporation on Wettability of Glass Polyalkenoate Cements A. Alhalawani1, D. Curran1, and M. Towler1 1

Poster Session

Fri

Ryerson University, Toronto, ON, Canada

P-Fri-25 Site-Specific and Enzyme-Mediated Modular Construction of Protein Complexes N. Bhokisham1, Y. Liu1, H. Pakhchanian1, G. Payne1, and W. Bentley1 1

University of Maryland, College Park, MD

P-Fri-26 Quantification of Stresses in Hydrogels using Photoelasticity G. Feuer1, M. Pendola1, and S. Saha1 1

SUNY Downstate, Brooklyn, NY

Track: Biomaterials

Biomaterials for Controlling Cell Environment Chairs: Hitesh Handa, Michael Fenn P-Fri-136 Encoding PEG Hydrogel Mechanics through Peptide Sequence to Regulate Endothelial Cell Morphogenesis R. Schweller1 and J. West1 1

Duke University, Durham, NC

P-Fri-137 Dual-crosslinked Hydrogel Microwell System for Formation and Culture of Multicellular Human Mesenchymal Stem Cell Spheroids O. Jeon1, D. Wolfson1, and E. Alsberg1 1

Case Western Reserve University, Cleveland, OH

1

P-Fri-139 Osseo-integration and Biofilm Formation on Different Ti-surfaces in a Post-operative Infection Model N. Ghimire1, B. Foss1, Y. Sun2, and Y. Deng1 The University of South Dakota, Sioux Falls, SD, 2The University of Massachusetts, Lowell, MA

1

P-Fri-140 Assessing the Osteoinductivity of Engineered Biomimetic Periosteum on Cortical Bone Allografts R. Romero1, L. Chubb1, E. Asbury1, A. Pennybaker1, J. Travers1, N. Ehrhart1, and M. Kipper1 1

)

144

BMES 2014

Colorado State University, Fort Collins, CO

P-Fri-141 Development of an in vitro Bladder Cancer Tissue Mimic and the Response to Cisplatin Treatment B. Balhouse1, A. Pekkanen1, M. Rylander1, and P. Vlachos2 1

Virginia Tech, Blacksburg, VA, 2Purdue University, West Lafayette, IN

P-Fri-142 Designing a Dynamically Tunable Photoresponsive Hydrogel for Studying Mechanotransduction W. Zhong1, C. Petchprayoon1, S. Li1, and G. Marriott1 1

University of California, Berkeley, Berkeley, CA

P-Fri-143 Poly-L-Arginine Based Materials As Instructive Substrates for Fibroblasts Synthesis of Collagen K. Bratlie1 1

Iowa State University, Ames, IA

P-Fri-144 Strain-Based Detachment of Intact Tissue Modules from Shape-changing Hydrogel O. Akintewe1, S. DuPont1, M. Cross1, K. Elineni1, R. Toomey1, and N. Gallant1 1

University of South Florida, Tampa, FL

P-Fri-145 Conformal Nanopatterning of Extracellular Matrix Proteins onto Topographically Complex Surfaces Q. Jallerat1, Y. Sun1,2, J. Szymanski1, and A. Feinberg1 Carnegie Mellon University, Pittsburgh, PA, 2Beihang University, Beijing, China, People's Republic of

1

P-Fri-146 Influence of Sparse Electrospun Fibers on the Differentiation of Mesenchymal Stem Cells in Collagen Gels P. Thayer1, E. Tong1, D. Plessl1, L. Dahlgren1, and A. Goldstein1 1

Virginia Tech, Blacksburg, VA

P-Fri-147 A Mechanistic Study of Collective Fibroblast Migration P. Sharma1, A. Kim1, C. Ng1, B. Behkam1, and A. Nain1 1

Virginia Tech, Blacksburg, VA

P-Fri-148 Rational And Combinatorial Biomaterial Screening Platform For Development Of Optimal Tissue Specific Biomaterials S. Ramamoorthy1, R. Jacobson1, J. Malcovitch1, C. Bertucci1, G. Saunders1, D. Thompson1, and P. Karande1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

UC Los Angeles, Los Angeles, CA

Rensselaer Polytechnic Institute, Troy, NY

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-149 Reducing Axon Retraction Events With Patterned Biomaterial Cues M. Wrobel1 and H. Sundararaghavan1 1

Biomaterials for Immunoengineering

Wayne State University, Detroit, MI

P-Fri-150 Electroconductive Hyaluronic Acid Hydrogel for Neuronal Differentiationof Human Neural Stem Cells J. Shin1, E. Choi2, K. Yang1, C. Song2, and S-W. Cho1 Yonsei University, seoul, Korea, Republic of, 2Sungkyunkwan University, Suwon, Korea, Republic of

1

P-Fri-151 Photo-Patterning Gelatin Hydrogels Using Caged Collagen Mimetic Peptides Y. Li1, J. Kessler1, and S. Yu1 1

University of Utah, Salt Lake City, UT

P-Fri-152 Carboxymethylcellulose Hydrogels Support CNS-derived Tumor Cell Chemotactic Migration T. Singh1, C. Kothapalli2, D. Varma1, S. Nicoll1, and M. Vazquez1 1

Track: Biomaterials

City College of New York-CUNY, New York, NY, 2Cleveland State University, Cleveland, OH

P-Fri-153 Orthopedic Implant Coating for Improved Osseointegration and Reduced Biofilm Formation

Chairs: Vassilios Sikacitsas, Daniel Alge

)

P-Fri-37 Bacterial Outer Membrane Vesicle Vaccines Carrying Arah2 Confer Prophylactic Protection Against Peanut Allergy T. Leung1, J. Rosenthal1, K. Mineta1, M. DeLisa1, and D. Putnam1 1

)

P-Fri-38 Microneedle-Based Immune Monitoring Platform Samples Cells and Interstitial Fluid from Tissue In Situ A. Mandal1, J. Van1, D. Irvine1,2,3,4, and P. Hammond1,5 Massachusetts Institute of Technology, Cambridge, MA, 2Koch Institute for Integrative Cancer Research, Cambridge, MA, 3Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 4Howard Hughes Medical Institute, Chevy Chase, MD, 5Koch Inst. for Integrative Cancer Research, Cambridge, MA

1

P-Fri-39 Cellular Mechanisms of Tolerance Involved in a Microparticle Vaccine for Type 1 Diabetes J. Stewart1, J. Lewis1, and B. Keselowsky1 1

L. Actis1, A. Srinivasan1, A. Ramasubramanian1, and J. Ong1 1

University of Texas at San Antonio, San Antonio, TX

P-Fri-154 Engineered Hydrogel System for Bone Regeneration Through Endochondral Ossification P. Mikael1 and S. Nukavarapu2

University of Florida, Gainesville, FL

P-Fri-40 Preventing Fibrosis of Hydrogels Implanted in Mice Using Immunomodulatory Agents S. Jhunjhunwala1, D. Lavin1, S. Aresta-DaSilva1, A. Santiago-Lopez1, R. Langer1, and D. Anderson1 1

University of Connecticut, Farmington, CT, 2University of Connecticut Health, Farmington, CT

Cornell University, Ithaca, NY

MIT, Cambridge, MA

1

P-Fri-155 Enhancing Neurite Outgrowth By Electrical Stimulation Through Conductive Nanofibers

P-Fri-41 Regulation of Macrophage Inflammatory Response by Immunomodulatory Poly(ethylene glycol) Hydrogels Y-T. Chen1, J. Schlosser1, Y. Kim1, and W. Liu1 1

E. Steel1 and H. Sundararaghavan1 1

Wayne State University, Detroit, MI

P-Fri-156 Fabrication of MgSiO3 Thin Film by RF Magnetron Sputtering Method to Accelerate Bone Formation S. Nakasaki , Y. Morita , T. Katayama , and E. Nakamachi 1

1

1

1

1

Doshisha University, Kyotanabe, Japan

P-Fri-157 Synthesis of a thermoreversible hydrogel for passaging adherent cells in three-dimensional culture

P-Fri-42 Reprogramming Macrophages by Engineering Polymer Surface Properties K. Bratlie1 1

Barrow Neurological Institute, Phoenix, AZ, 2Arizona State University, Tempe, AZ

P-Fri-158 Fibroblast and Macrophage Cell Viability on Polyelectrolyte Complex

R. Krishnan1, B. Buder1, M. Alexander1, C. Foster III1, and J. Lakey1 1

Rutgers University, Piscataway, NJ

P-Fri-159 Biofilm Accumulation on Medical Device Materials With Varied Surface Roughness A. Macaluso1, A. Crites1, and M. Harman1 Clemson University, Clemson, SC

1

P-Fri-160 The Study of Platelet Adhesions using Bovine Whole Blood versus Platelet Rich Plasma Comparing Percent Surface Aggregate Coverage

University of California Irvine, Orange, CA

P-Fri-44 Electrospun Microfiber Nanotopography Alters Macrophage Polarization N. Schaub1, E. Harmon2, M. Lennartz2, and R. Gilbert1 1

S. Mistry1, K. Desai1, R. Schloss1, and N. Langrana1 1

Iowa State University, Ames, IA

P-Fri-43 Young Porcine Islets Encapsulated in Alginate Microcapsules can maintain Prolonged Euglycemia after Transplantation into Diabetic Athymic Nude Mice

J. Heffernan1,2, D. Overstreet1, S. Srinivasan2, B. Vernon2, and R. Sirianni1,2 1

University of California, Irvine, Irvine, CA

Rensselaer Polytechnic Institute, Troy, NY, 2Albany Medical College, Albany, NY

P-Fri-45 Macrophage Response to Titanium Surface Characteristics K. Hotchkiss1, Z. Schwartz1, S. Hyzy1, B. Boyan1, and R. Olivares-Navarrete1 1

Virginia Commonwealth University, Richmond, VA

P-Fri-46 Assessment And Control Of Anti-Microbial And Anti-Inflammatory Response Of Macrophages to Different Surface Nanomodifications G. Bhardwaj1 and T. Webster1 1

Northeastern University, Boston, MA

G. Williamson1, A. Bujana1, M. Rush1, and M. Watson1 LeTourneau University, Longview, TX

1

See page 141 for Poster floor plan

BMES 2014

145

Poster Session

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-47 Antigen-Specific Immune Response of a PLGA Microparticle-Based DNA Vaccine against Ureaplasma

P-Fri-604 Experimental Validation of CFD Simulations of a Patient-Specific Pulmonary Vascular Model Using Stereoscopic Particle Image Velocimetry

Q. Wang1, L. Weisman1,2, A. Leeming1,2, and M. Heffernan1

M. Leroux1, V. Kheyfets1, and E. Finol1

1

Baylor College of Medicine, Houston, TX, 2Texas Children's Hospital, Houston, TX

P-Fri-48 Endotoxin Contamination In Chitosan And Its Effect On Immune Response S. Ravindranathan1, S. Smith1, B. Koppolu1, S. Kurtz1, and D. Zaharoff1

1

P-Fri-605 Changes in Cardiac Tissue Properties Relative to the Applications of Radiofrequency or Cryo Ablative Therapies S. Quallich1, K. Kriege1, and P. Iaizzo1

University of Arkansas, Fayetteville, Fayetteville, AR

1

1

T. Tan1 and R. De Vita1 1

Cardiovascular Biomechanics Chairs: Aaron Baker, Jun Liao

)

P-Fri-596 Effect of Annuloplasty Ring Size: Patient-Specific Finite Element Evaluation The University of Texas Health Science Center at Houston, Houston, TX

1

)

P-Fri-597 Hemodynamic Shear Stress And Biochemical Regulation Of Cathepsin K Activity In Sickle Cell Disease S. Anbazhakan1, P. Keegan1, and M. Platt1 Georgia Institute of Technology, Atlanta, GA

1

P-Fri-598 Numerical Modeling of Magnetic Micropump for Biogenic Bulk Transport in a Biomimetic Microchannel E. Ige1, A. Dare1, and A. Coker1

Fri

University of Ibadan, Ibadan, Nigeria

P-Fri-599 Measurement of Endothelial Permeability Under Chronic Applied Shear Stress in a Bioreactor S. Gray1, P. Weinberg1, D. Overby1, and A. Randi1 Imperial College London, London, United Kingdom

1

P-Fri-600 Experimental Validation of an Algorithm for the Zero Pressure Geometry Derivation of Blood Vessels G. Vimalatharmaiyah1, S. Chandra1, J. Rodriguez2, and E. Finol1 1 University of Texas at San Antonio, San Antonio, TX, 2Universidad de Zaragoza, Zaragoza, Spain

P-Fri-601 On the Biomechanical Behavior of the Layers of the Mitral Valve Anterior Leaflet S. Ayoub1 and M. Sacks 1 1

The University of Texas at Austin, Austin, TX

P-Fri-602 Active Stresses In The Porcine Common Carotid Artery B. Zhou , T. Shazly , G. Brower , , H. Doviak , , and F. Spinale 1

1

2 3

2 3

L. Shrestha1, V. Magnotta1, N. Grosland1, D. Calceterra1, and S. Vigmostad1 1

P-Fri-603 Effects of Arterial Wall Local Softening on Pulse Wave Propagations and Velocities Stevens Institute of Technology, Hoboken, NJ

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

146

BMES 2014

P-Fri-608 Artery Buckling Analysis using A Four-Fiber Wall Model Q. Liu1, M. Mottahedi1, and H-C. Han1 1

University of Texas at San Antonio, San Antonio, TX

P-Fri-609 Finite Element Analysis of the Mechanics of Neovessels with Intraplaque Hemorrhage in Carotid Atherosclerosis J. Lu1 and A. Qiao1 1

Beijing University of Technology, Beijing, China, People's Republic of

P-Fri-610 Prior Distribution of Material Parameters for a Computational Model of the Abdominal Aorta S. Seyedsalehi1, L. Zhang1, J. Choi1, and S. Baek1 1

Michigan State University, East Lansing, MI

P-Fri-611 Fluid Structure Interaction Human Left Ventricular Modelling Using an Immersed Boundary-Finite Element Method H. Gao1, D. Carrick1, C. Berry1, B. Griffith2,3, and X. Luo1 University of Glasgow, Glasgow, United Kingdom, 2University of North Carolina at Chapel Hill, Chapel Hill, NC, 3University of North Carolina School of Medicine, Chapel Hill, NC

1

P-Fri-612 Microfluidic Stiffness-Dependent Separation of Aged Erythrocytes for Improved Blood Storage and Purification R. Byler1,2, K. Patel2, L. Hall2, A. Zhen2, and T. Sulchek2 1

Yale University, New Haven, CT, 2Georgia Institute of Technology, Atlanta, GA

)

P-Fri-613 Computational Evaluation of Restoration of Mitral Valve Function Following Quadrangular Leaflet Resection and Ring Annuloplasty 1

2

University of South Carolina, Columbia, SC, 2University of South Carolina School of Medicine, Columbia, SC, 3WJB DORN Veteran Affairs Medical Center, Columbia, SC

1

The University of Iowa, Iowa City, IA

Y. Rim1, A. Choi1, D. McPherson1, and H. Kim1

1

I. Inga1 and D. Shahmirzadi1

Virginia Tech, Blacksburg, VA

P-Fri-607 Development of User Interactive Toolkit for Modeling Patient Specific Geometries without Volumetric Mesh

A. Choi1, Y. Rim1, D. McPherson1, and H. Kim1

1

University of Minnesota, Minneapolis, MN

P-Fri-606 Structural Constitutive Model For Smooth Muscle Contraction

Track: Biomechanics, Cardiovascular Engineering

Poster Session

University of Texas at San Antonio, San Antonio, TX

The University of Texas Health Science Center at Houston, Houston, TX

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-625 Mechanical Properties of Erythrosensors

Track: Biomechanics, Cellular and Molecular Bioengineering

S. Bustamante Lopez1, S. Ritter1, and K. Meissner1 1

Cell Biomechanics

P-Fri-626 Effect of Substrate Stiffness on Force Generation by Airway Smooth Muscle Cells

)

P-Fri-614 Mechanical Biomarkers of Embryo Viability L. Zarnescu1, J. Han1, B. Behr1, R. Reijo Pera1, and D. Camarillo1 1

P-Fri-615 Depletion of Linker Histone H1 Increases Cellular and Nuclear Young's Moduli T. Bongiorno , T. McDevitt , , Y. Fan , and T. Sulchek , 1

1 2

1

1 2

Georgia Institute of Technology, Atlanta, GA, 2Emory University, Atlanta, GA

P-Fri-616 Intrinsically Disordered Proteins Drive Membrane Curvature of Clathrin Coated Vesicles D. Busch1, J. Houser1, S. Jafri1, J. Jose1, and J. Stachowiak1 1

University of Texas at Austin, Austin, TX

P-Fri-617 The Effect Of Soluble Factors Released By Mechanically Stimulated Osteocytes On the Mineralization Capacity Of Osteoblasts J. McPherson1, S. York1, A. Sewell1, and M. Saunders1 1

C. Wang1, M. Perez1, B. Helmke1, F. Viola1, and M. Lawrence1 University of Virginia, Charlottesville, VA

P-Fri-619 How Single Stress Fiber Mechanics Depend on Length and Adhesive Spacing E. Kassianidou1 and S. Kumar2 UC Berkeley -UCSF Joint Program in Bioengineering, Berkeley, CA, 2University of California, Berkeley, CA

Boston University, Boston, MA

P-Fri-627 Osteocyte Viability Changes In Response To Microdamage S. York1, J. King1, A. Pietros1, B-M. Zhang Newby1, P. Sethu2, and M. Saunders1 1

University of Akron, Akron, OH, 2University of Alabama Birmingham, Birmingham, AL

P-Fri-628 Mechanics of Epithelial to Mesenchymal Transition in Cancer and NonCancer Models L. Volakis1, D. Kniss2, and S. Ghadiali2 The Ohio State University, Columbus, OH, 2The Wexner Medical Center at The Ohio State University, Columbus, OH

1

P-Fri-629 Rest Periods May Increase Mechanically Stimulated MSC's Promotion of Osteoblast Proliferation B. Yu1, G. Lee2, A. Yang2, M. Chan2, and C. Rubin2 1

University of Akron, Akron, OH

P-Fri-618 Acoustic Radiation Force Based Clot Stiffness Assessment Is Highly Sensitive to Platelet Number and Activation 1

H. Parameswaran1, S. Polio1, E. Canovic1, B. Harvey1, B. Suki1, M. Smith1, and K. Lutchen1 1

Stanford University, Stanford, CA

1

Texas A&M, College Station, TX

Stony Brook University, Tarrytown, NY, 2Stony Brook University, Stony Brook, NY

P-Fri-630 Contribution of Different Collagen IV Isoforms to Glomerular Basement Membrane Mechanics L. Gyoneva1, Y. Segal1, K. Dorfman1, and V. Barocas1 1

University of Minnesota - Twin Cities, Minneapolis, MN

P-Fri-631 Measurement Of Cell Traction Force With A Thin PDMS Cantilever

Poster Session

Fri

M. Holley1, E. Song1, A. Moll1, D. Hayes1, W. Monroe1, J-W. Choi1, and K. Park1 1 Louisiana State University, Baton Rouge, LA

1

P-Fri-620 The Cell as a Pump: Cytoskeletal Contractions Drive Intercellular Fluid Flow S. Zehnder1, A. Dunn1, J. Urueña1, W. Sawyer1, and T. Angelini1 1

University of Florida, Gainesville, FL

P-Fri-621 Characterizing Dendritic Cell Motility on PDMS Surfaces

J. Kazlow1,2, T. Bongiorno1, and T. Sulchek1 1

Georgia Institute of Technology, Atlanta, GA, 2Emory University, Atlanta, GA

P-Fri-633 Shear Stimulated Differentiation of Bone Marrow Derived hMSCs Towards the Chondrocytic Lineage A. Adeniran-Catlett1 and S. Murthy1 1

A. Chevalier1 and D. Hammer1 1

P-Fri-632 F-Actin Arrangement as an Indicator of Stiffness in Undifferentiated Mesenchymal Stem Cells

University of Pennsylvania, Philadelphia, PA

P-Fri-622 Understanding Cell Viability and Mechanics of Actin Filament Response of NIH/3T3 Fibroblasts Under Biaxial Stretch

Northeastern University, Boston, MA

P-Fri-634 Resistive-Pulse Differentiation of Metastatic and Non-metastatic Tumor Cells with Solid-state Micropores W. Ali1, A. Ilyas1, Y-T. Kim1, and S. Iqbal1 University of Texas at Arlington, Arlington, TX

H. Ghazizadeh1, S. Ravari2, A. Hung1, D. LaJeunesse2, and S. Aravamudhan1

1

North Carolina A&T State University, Greensboro, NC, University of North Carolina at Greensboro, Greensboro, NC

P-Fri-635 Characterization Of A Microloading Platform For In Vitro Mechanotransduction Studies

1

2

P-Fri-623 Designing Next Generation Stem Cell Mechanics Studies for Prospective Guidance of Lineage Commitment H. Chang1, M. Song2, and M. Knothe Tate3 Case Western Reserve University, Cleveland, OH, 2University of Pennsylvania, Philadelphia, PA, 3University of New South Wales, UNSW Sydney, Australia

1

P-Fri-624 Finite Element Modeling of 3D Cell Migration through a Fibrous Matrix

S. York1 and M. Saunders1 1

University of Akron, Akron, OH

P-Fri-636 Quantification Of Gap Junction Communication And Sclerostin Expression In Microdamaged Osteocytes S. York1, P. Sethu2, and M. Saunders1 1

University of Akron, Akron, OH, 2University of Alabama Birmingham, Birmingham, AL

R. Zielinski1 and S. Ghadiali1,2 The Ohio State Univeristy, Columbus, OH, 2The Dorothy M. Davis Heart & Lung Research Institute, Columbus, OH

1

See page 141 for Poster floor plan

BMES 2014

147

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-637 Computational Model of Fluid Flow During Cyclic Mechanical Loading of Cultured Cells

P-Fr-2 Development and Characterization of Tissue-mimicking Anisotropic Gel for MR Elastography

J. Lee1, Q. Smith1, and A. Baker1

C. Walker1, M. Mahoney1, M. Mathison1, S. Raven1, J. Schmidt1, R. Okamoto1, and P. Bayly1

1

University of Texas at Austin, Austin, TX

1

P-Fri-638 Bio-mechanical Characteristics of Normal and Cancerous Cells - A Computational Study T. Brady1 and V. Unnikrishnan1 1

The University of Alabama, Tuscaloosa, AL

P-Fri-639 A Microfluidic Device for Investigation of Cellular Migration and Invasion in Response to Chemical and Physical Stimuli S. Bean1, L. Lee1, S. Rao1, V. Lin1, and J-C. Chiao1 1

UT Arlington, Arlington, TX

P-Fri-640 Probing Microalgal Response Using Atomic Force Microscopy K. Warren1, J. Mpagazehe1, C. Higgs III1, and P. LeDuc1 1

Carnegie Mellon University, Pittsburgh, PA

Washington University in Saint Louis, Saint Louis, MO

P-Fr-3 Probing Mechanical Tension in Human Fibroblast Collagen Lattices L. Tinnin1, C. Anderson1, M. Vaughan1, and G. Xu1 1

University of Central Oklahoma, Edmond, OK

P-Fr-4 Effect of Amyloid Beta on Mechanical Properties and Structure of Extracellular Matrix Y. Jeon1, S. Jo1, B. Kang1, and H. Lee1 1

Yonsei University, Seoul, Korea, Republic of

P-Fr-5 Numerical Analysis of Vortex Entrapment of Particles with Respect to Bacterial Adhesion on Implants H. Basagaoglu1, J. Carrola1, C. Freitas1, B. Basagaoglu2, and M. DeSilva3 Southwest Research Institute, San Antonio, TX, 2Texas A&M University, College Station, TX, 3Navy Medical Research Unit, Fort Sam Houston, TX

1

P-Fri-641 Migratory Behavior of Breast Cancer Cells in Conditioned Medium from Human Osteosarcoma Cells S. Loh1, L. Lee1, S. Bean1, S. Rao1, V. Lin1, and J-C. Chiao1 1

UT Arlington, Arlington, TX

P-Fri-642 Biomechanical Characterization of Algal Motility in Response to Medium Viscosity K. Clark1, D. Fijalka1, J. Johnson1, M. Mashburn1, S. Karpowicz1, and G. Xu1 1

Poster Session

Fri

University of Central Oklahoma, Edmond, OK

P-Fr-6 Pull-off Stress Evaluation of Commercially Available Wound-Treatment Polymers R. Thornton1, V. Kheyfets2, and E. Finol1 University of Texas at San Antonio, San Antonio, TX, 2University of Colorado Denver, Denver, CO

1

P-Fr-7 Long Range Force Transmission Enabled by Formation of Aligned Fibers in Collagen Matrices

P-Fri-643 Squishy DNA Nanoparticles

V. Shenoy1, H. Wang1, A. Nair1, and R. Wells1

S. Cook1, K. Curtis2, S. Beharie2, E. Dimitriadis3, F. Horkay3, and P. Chandran2

P-Fr-8 Removal of Proteoglycans from Bone Matrix Significantly Reduce its In Situ Toughness

Case Western Reserve University, Cleveland, OH, 2Howard University, Washington, DC, DC, 3National Institutes of Health, Bethesda, MD

1

P-Fri-644 Model of Oxidative Stress in the Aging Lens C. Gutierrez Candano1 1

UTSA, San Antonio, TX

P-Fri-645 Nanomechanics of Human Adipose Stem Cells in Micromass during Chondrogenesis C. Quisenberry1, A. Nazempour1, B. Van Wie1, and N. Abu-Lail1 1

Washington State University, Pullman, WA

1

University of Pennsylvania, Philadelphia, PA

H. Xu1, A. Sheldrake1, J. Jiang2, and X. Wang1 University of Texas at San Antonio, San Antonio, TX, 2University of Texas Health Science Center at San Antonio, San Antonio, TX

1

P-Fr-9 Dynamic Drying Mechanics of Human Stratum Corneum and the Effects of Moisturization X. Liu1 and G. German1 1

Binghamton University, Binghamton, NY

Track: Biomechanics, Biomaterials

P-Fr-10 Comparison Of Microstructural, Biomechanical and Suture Retention Strength Of Ovine Vaginal Patches Obtained From Three Types Of Decellularization Protocols.

Mechanics of Biomaterials

S. Patnaik1, J. Butler1, B. Brazile1, B. Weed1, V. Dandolu2, D. Christiansen1, P. Ryan1, and J. Liao1

Chairs: Vittoria Flamini, Jason Gleghorn P-Fr-1 Shear Properties of PNIPAAm-g-CS Hydrogels T. Mauriello1, S. Gossert1, G. Feil1, A. Vernengo1, and J. Kadlowec1 1

Rowan University, Glassboro, NJ

Mississippi State University, Mississippi State, MS, 2University of Nevada School of Medicine, Las Vegas, NV

1

P-Fr-11 Quantifying The Effects of Decellularization on Liver Perfusion Dynamics K. Nishii1, E. Moran2, G. Reese1, and J. Sparks1 Miami University, Oxford, OH, 2VT-WFU School of Biomedical Engineering and Sciences, Winston Salem, NC

1

P-Fr-12 Modeling Strain Distributions in Uniaxially Mechanically Loaded Acellular ECM-based Scaffolds B. Seifer1 and C. Wagner1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

148

BMES 2014

The College of New Jersey, Ewing, NJ

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM

Track: Biomedical Imaging and Optics

Track: Biomedical Imaging and Optics

Novel Approaches to Biomedical Imaging

Optical Imaging and Microscopy

Chairs: Craig Goergen

P-Fri-338 Near-Infrared Spectroscopic Photoacoustic Microscopy using a Pulsed Multi-Color Source based on Stimulated Raman Scattering

Chairs: Kaushik Parthasarathi

)

P-Fri-329 Single Molecule Tracking In Vivo Using Spatiotemporally Multiplexed TwoPhoton Microscopy K. Huynh1, E. Perillo1, Y-L. Liu1, H-C. Yeh1, and A. Dunn1 1

1

Colorado State University, Fort Collins, CO, 2Universidade de São Paulo, São Paulo, Brazil

P-Fri-331 Gold Nanoparticles as Exogenous Soft Tissue Contrast for Live In Vivo MicroCT Imaging of Avian Morphogenesis

G. Madejski1 and J. McGrath1 University of Rochester, Rochester, NY

P-Fri-333 Near-Infrared Switchable Fluorescent Nano-capsules for Temperature Sensing and USF Imaging 1 2

3

1 2

1 2

University of Texas at Arlington, Arlington, TX, 2The University of Texas Southwestern Medical Center at Dallas, Dallas, TX, 3University of North Texas, Denton, TX

P-Fri-334 Quantification of TiO2 Nanoparticle Uptake by Single Cells and Distribution Across a Population by Synchrotron X-ray Fluorescence J. Rashkow , S. Patel , R. Tappero , and B. Sitharaman 1

1

2

1

Stony Brook University, Stony Brook, NY, 2National Synchrotron Light Source, Upton, NY

P-Fri-335 Fluorescent Based Fiber Optics Imaging On Electrospun Scaffold E. Sapoznik1,2, G. Niu2, P. Lu3, Y. Zhou2, T. Criswell2, F. Marini2, Y. Xu3, and S. Soker1,2 Virginia Tech-Wake Forest School of Biomedical Engineering and Sciences, Winston Salem, NC, 2Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, 3Virginia Tech, Blacksburg, VA

1

P-Fri-336 3D Surface Imaging of the Human Female Torso in Upright to Supine Positions G. Reece1, F. Merchant2, H. Khatam1,3, K. Ravi-Chandra3, J. Weston1, M. Fingeret1, C. Lane4, K. Duncan4, and M. Markey1,3 The University of Texas MD Anderson Cancer Center, Houston, TX, University of Houston, Houston, TX, 3The University of Texas at Austin, Austin, TX, 43dMD, LLC, Atlanta, GA

1

P-Fri-342 Simultaneous Imaging of Oxygen Tension and Blood Flow During Stroke Using a Digital Micromirror Device

L. Shi , A. Rodriguez-Contreras , and R. Alfano 1

1

City College of New York, New York, NY

1

The University of Texas at Austin, Austin, TX

P-Fri-343 Using Bayesian Analysis to Improve Flow Velocity Measurement Precision in Optical Coherence Tomography K. Zhou1, B. Huang1, and M. Choma1 1

Yale University, New Haven, CT

P-Fri-344 Three-photon Excitation Spectra of Fluorescent Dyes for In Vivo Imaging D. Miller1, F. Cianchetti1, and A. Dunn1 1

The University of Texas at Austin, Austin, TX

Track: Biomedical Imaging and Optics

Ultrasound Chairs: Mario Fabilli

)

P-Fri-345 Relationship between Secondary Radiation Force, Targeted Adhesion, and Microbubbles Acoustic Response in Large Blood Vessels S. Wang1, C. Wang1, F. Mauldin Jr1, and J. Hossack1 1

2

P-Fri-337 Deeper Two-Photon Microscopy Imaging through Brain Tissue using S2 State of Chl α in Spinach Leaf 1

Swiss Federal Institute of Technology, Lausanne, Switzerland, 2The Weizmann Institute of Science, Rehovot, Israel, 3Khalifa University of Science, Abu Dhabi, United Arab Emirates

1

1

1

1

A. Magold1,2, J. Teo3, and M. Swartz1

C. Sullender1, A. Mark1, and A. Dunn1

M. Wei , , B. Cheng , , V. Bandi , , Y. Liu , , F. D'Souza , K. Nguyen , , Y. Hong , , and B. Yuan1,2 2 3

University of Texas Medical Branch, Galveston, TX

P-Fri-341 Tracking Cerebrospinal Fluid Flow in Murine Lateral Ventricles

Cornell University, Ithaca, NY

1 2

P-Fri-340 Well Resolved Two-Phase Optical Clearing by Hyperosmotic Agents: Application for High Resolution Deep Brain Imaging 1

P-Fri-332 Nanoporous Magnesium Fluoride Substrates for Raman-Compatible Cell Culture

1 2

Union College, Schenectady, NY

L. Ochoa1, A. Kholodnykh1, L. Vergara1, G. Vargas1, and M. Motamedi1

C. Gregg1, H. Zhao1, and J. Butcher1

1

Union College, Schenectady, NY

T. Sheehan1, B. Wilkinson1, and T. Buma1

M. Mellenthin1, E. Darío León Bueno de Camargo2, F. Silva de Moura2, T. Batista Rattis Santos2, J. Mueller1, and R. Gonzalez Lima2

1

1

P-Fri-339 Spectroscopic Photoacoustic Microscopy with a Multi-Color Pulsed Laser using a Multimode Optical Fiber

The University of Texas at Austin, Austin, TX

P-Fri-330 Complex Voltage Measurements With Active Electrodes In Electrical Impedance Tomography 1

B. Wilkinson1, T. Sheehan1, and T. Buma1

University of Virginia, Charlottesville, VA

P-Fri-346 Ultrasound Imaging of Microfluidic-Produced Microbubbles Directly Injected Into A Mouse Via A Tail Vein Catheter A. Dixon1, A. Dhanaliwala1, D. Lin1, A. Klibanov1, and J. Hossack1 1

University of Virginia, Charlottesville, VA

P-Fri-347 High-frequency Side-looking Phased Array for Colorectal Ultrasound Imaging N. Cabrera-Munoz1, H. Kim1, J. Williams1, and K. Shung1 1

University of Southern California, Los Angeles, CA

See page 141 for Poster floor plan

BMES 2014

149

Poster Session

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-348 A Single-Element Ultrasound Viscoelastography System for Point-of-Care Edema Quantification J. Pitre1, L. Kozoil1,2, G. Kruger1, W. Weitzel1,2, and J. Bull1 1

University of Michigan, Ann Arbor, MI, 2VA Medical Center, Ann Arbor, MI

P-Fri-349 High Frequency Optoacoustic Sensor Based on a Microsphere Resonator K. Hammer1 and T. Buma1 1

Kitasato University, Sagamihara, Japan, 2Hitachi Ltd, Sitama, Japan, 3Kitasato Univercity, Sagamihara, Japan, 4Accelerator Research Organization, Tsukuba, Japan

1

P-Fri-359 Structural Change of Rat's Spleen by Phase-Contrast X-Ray CT Kitasato University, Sagamihara, Japan, 2Hitachi Ltd, Saitama, Japan, 3High Energy Accelerator Research Organization, Tsukuba, Japan

P-Fri-350 Optically Activated Ultrasound Contrast Agents for Diagnostic Imaging

1

A. Hannah1 and S. Emelianov1

P-Fri-360 Freeze-Thaw Kidney Imaging by Phase-contrast X-ray CT

University of Texas at Austin, Austin, TX

P-Fri-351 High Frequency Ultrasound Array in Biopsy Needle for Breast Cancer Imaging T. Cummins1, H. Choi1, P. Eliahoo1, H. Kim1, M. Yamashita1, L. Larsen1, J. Lang1, S. Sener1, J. Vallone1, S. Martin1, and K. Shung1 1

University of Southern California, Los Angeles, CA

P-Fri-352 Low-Frequency Radial Imaging Array for Ultrasound-Navigated Spinal Fusion Surgery A. Manbachi , H. Ginsberg , , and R. Cobbold 1

1

1 2

1

University of Toronto, Toronto, ON, Canada, 2St. Michael's Hospital, Toronto, ON, Canada

P-Fri-353 Automatic Real-Time Reconstruction of 3D Patient Specific Bones from RF Ultrasound Data M. Mahfouz , E. Abdel Fatah , and G. To 1

1

Fri

T. Takeda1, T-T. Lwin1, A. Yoneyama2, J. Wu1, R. Shirai1, M. Taguchi3, S. Esashi3, T. Matsushima3, H. Maruyama1, and K. Hyodo4

S. Esashi1, A. Yoneyama2, T-T. Lwin1, M. Taguchi1, T. Matsushima1, H. Maruyama1, K. Hyodo3, and T. Takeda1

Union College, Schenectady, NY

1

Poster Session

P-Fri-358 3D White Matter Imaging of Rat Obtained by Phase-Contrast X-Ray CT

1

1

University of Tenenssee, Knoxville, TN

P-Fri-354 Synergy Between High-intensity Focused Ultrasound and Ethanol Injection in Thyroid Cancer Ablation In Vitro and In Vivo

M. Taguchi1, A. Yoneyama2, S. Takeya3, T-T. Lwin1, S. Esashi1, H. Maruyama1, K. Hyodo4, and T. Takeda1 Kitasato University, Sagamihara, Japan, 2Hitachi Ltd, Saitama, Japan, 3National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan, 4High Energy Accelerator Research Organization, Tsukuba, Japan 1

P-Fri-361 An Optimized Thresholding Reconstruction Approach for the Lp (0
P-Fri-362 Exploring the Spatial Resolution Limits of Positron Emission Tomography Imaging A. Varshney1,2, T. Cao1,2, and P. Vaska1,2 SUNY - Stony Brook University, Stony Brook, NY, 2Brookhaven National Laboratory, Upton, NY

1

P-Fri-363 Arterial vs Venous Input Function: Full Quantification of 11C-ABP using Positron Emission Tomography S. Rossano1 and C. DeLorenzo1 1

H. Murad1, N. Hoang1, K. Tsumagari1, E. Kandil1, and D. Khismatullin1 1

Tulane University, New Orleans, LA

P-Fri-355 Development and Characterization of Tissue-Mimicking Gelatin Phantoms for use with MRgFUS A. Farrer1, H. Odéen1, J. de Bever1, B. Coats1, D. Christensen1, and A. Payne1 1

University of Utah, Salt Lake City, UT

Track: Biomedical Imaging and Optics

)

A. Hoppe1, D. Hasan1, and M. Raghavan1 1

H. GONG1 and G. Cao1 1

Virginia Polytechnic Institute and State University, Blacksburg, VA

P-Fri-357 Hippocampus Layers Imaging of Mouse by Phase Contrast X-Ray CT T-T. Lwin1, A. Yoneyama2, R. Shirai1, M. Taguchi1, S. Esashi1, T. Matsushima1, H. Maruyama1, K. Hyodo3, and T. Takeda1 Kitasato University, Sagamihara, Japan, 2Hitachi Ltd, Saitama, Japan, 3High Energy Accelerator Research Organization, Tsukuba, Japan

1

University of Iowa, Iowa City, IA

P-Fri-365 Functional Connectivity Mapping Across The Rodent Cerebral Cortex: Method And Implementation For Animal Autoradiographic Imaging Y-H. Peng1, D. Holschneider1, Y. Guo1, Z. Wang1, and J-M. Maarek1 1

P-Fri-356 Interior Micro-CT for Radiation Dose Reduction

Stony Brook University, Stony Brook, NY

P-Fri-364 An Image Processing Protocol for Assessing Longitudinal Growth of Coil Embolized Cerebral Aneurysms and their Corresponding Coil Masses

X-ray, CT and Nuclear Medicine Chairs: Ted Trouard

Wake Forest University, Winston-Salem, NC

University of Southern California, Los Angeles, CA

Track: Cancer Technologies, Nano to Micro Technologies

Microtechnologies for Cancer Chairs: Kapil Pant, Aram Chung

)

P-Fri-176 A Microfluidic Device for Dissociating Tumor Tissue into Single Cells X. Qiu , J. De Jesus1, M. Pennell1, M. Troiani1, and J. Haun1 1

1

University of California, Irvine, Irvine, CA

P-Fri-177 A Microfluidic Platform to Evaluate the Role of Vessel Permeability in Tumor Cell Extravasation L. Blaha1, C. Zhang1, R. Alani2, M. Cabodi1, and J. Wong1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

150

BMES 2014

Boston University, Boston, MA, 2Boston University School of Medicine, Boston, MA

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-178 Tagless Discrimination And Detection Of Cancer Cells Using Solid-State Micropores

P-Fri-189 Circulating Pancreatic Cells for Risk Stratification of Patients with Precancerous Pancreatic Cyst Lesions

A. Ilyas1, W. Ali1, J-T. Hsieh2, Y. Lotan2, Y-T. Kim1, and S. Iqbal1

F. Thege1, T. Lannin1, T. Saha2, K. Das3, A. Rhim2, and B. Kirby1,4

University of Texas at Arlington, Arlington, TX, University of Texas Southwestern Medical Center at Dallas, Dallas, TX

1

2

1

P-Fri-179 Double-Filter Based Enrichment of Circulating Tumor Cells Increases Efficiency and Purity of Captured CTCs A. Sanati Nezhad1, J. Hernandez-Castro1, K. Turner1, and D. Juncker1 1

McGill University, Montreal, QC, Canada

M. Cox1 and S. Verbridge1 Virginia Tech, Blacksburg, VA

P-Fri-181 A Microchip Platform for Interrogating Tumor-Immune Cell Communication at the Single-Cell M. Elitas1, K. Brower2, Y. Lu1, J. Chen1, and R. Fan1 1

Yale Unv., New Haven, CT, 2Isoplexis Inc, New Haven, CT

P-Fri-182 Development of a Microfluidic Device to Study the Role of Mechanobiology on Endothelial to Mesenchymal Transformation S. Mina1, W. Wang1, Q. Cao 1, B. Murray 1, P. Huang 1, and G. Mahler 1 1

P-Fri-190 Novel Tunable Functionalized Surface for the Isolation of Tumor Associated Cells A. Ansari1 and P. Imoukhuede1 1

P-Fri-180 A Microfluidic Device to Analyze Vascular Dynamics in a Heterogeneous Brain Tumor Microenvironment 1

Cornell University, Ithaca, NY, 2University of Michigan School of Medicine, Ann Arbor, MI, Massachusetts General Hospital & Harvard Medical School, Boston, MA, 4Weill Cornell Medical College, New York, NY

3

Binghamton University, Binghamton, NY

P-Fri-183 A poly(dimethyl siloxane) Microfluidic Device for in situ Imaging of Cellular Migration and Invasion in Response to Chemical Signaling L. Lee1, S. Rao1, V. Lin1, and J-C. Chiao1

University of Illinois at Urbana-Champaign, Urbana, IL

Track: Cancer Technologies

Personalized Medicine, Imaging, and Immunoengineering Strategies in Cancer Chairs: Catherine Whittington, Gregory Hudalla P-Fri-191 Novel Immunosensor: Dual Ionophore Concept Based on an Ion Selective Electrode X. Li1, C. Berkman1, J. Geruntho1, B. Van Wie (PI)1, and D. Kidwell2 1

Washington State University, Pullman, WA, 2Naval Research Laboratory, SW, DC

P-Fri-192 Decreased T2 Relaxation and Increased Calcification In Articular Cartilage Following Modelled Therapeutic Irradiation At Long-Term Followup I. Hutchinson1, J. Olson1, A. Lindburg1, B. Collins2, T. Smith1, M. Munley1, K. Wheeler1, and J. Willey1 Wake Forest Baptist Health, Winston Salem, NC, 2North Carolina A&T State University, Greensboro, NC

1

UT Arlington, Arlington, TX

1

P-Fri-184 High Throughput 3D Cell Migration Assay to Elucidate the Underlying Mechanisms of Metastasis M-E. Brett1 and D. Wood1

P-Fri-193 A Gold Nanoparticle Contrast Agent for Lung Cancer CT Imaging Using Novel EGFR-Specific VHH Domains J. Ashton1, E. Gottlin2, E. Patz2, J. West1, and C. Badea2

University of Minnesota, Minneapolis, MN

1

1

P-Fri-185 Measuring Oxygenation In Intuitive Tumor Tissue Model Using a Gold Microelectrode Array A. Bubie1 and M. Gratzl2 Case Western Reserve University, Cleveland Heights, OH, 2Case Western Reserve University, Cleveland, OH

1

P-Fri-186 Label-Free Viable-Enrichment of Circulating Tumor Cells From Clinical Blood Samples with the FMSA Device R. Harouaka1, M. Zhou1, Y-T. Yeh1, W. Khan1, and S. Zheng1

Duke University, Durham, NC, 2Duke University Medical Center, Durham, NC

P-Fri-194 Development of Shape Coded Hydrogel Micro-particles for Simultaneous Detection of Multiple Biomolecules M. Al-Ameen1, J. Li1, and G. Ghosh1 1

University of Michigan Dearborn, Dearborn, MI

P-Fri-195 Study of Synergisticcryo-thermal Treatment Modality Against Metastatic Breast Cancer Through Induction of Long-lasting Immune Responses P. Liu1, J. Liu1, and L. Xu1 School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, People's Republic of

1

The Pennsylvania State University, University Park, PA

1

P-Fri-187 Live Imaging of Microfiltration to Optimize the Purity of Isolated Circulating Tumor Cells K. Turner1,2, A. Sanati Nezhad1,2, J. Alejandro Hernandez-Castro1,2, and D. Juncker1,2

P-Fri-196 Exploring Biomarkers for Point of Care Bladder Cancer Detection C. Walker1, S. Smith1, and D. Zaharoff1 1

University of Arkansas, Fayetteville, Fayetteville, AR

McGill University, Montreal, QC, Canada, Genome Quebec Innovation Centre, Montreal, QC, Canada

P-Fri-197 In Vivo Capture and Label-free Detection of Early Metastatic Cells

P-Fri-188 Automated, High Throughput 3D Culture Microtechnology for Anticancer Drug Testing

J. Yi1, S. Azarin1, L. Shea1, and V. Backman1

1

2

S. Lemmo1 and H. Tavana1 1

University of Akron, Akron, OH

1

Northwestern University, Evanston, IL

P-Fri-198 Circulating microRNAs Detection in Patients with Hepatocelluar Carcinoma by Tethered Lipoplex Nanoparticles (TLN) X. wang1, Z. Yang1, J. ma1, K. Kwak 1, R. Sullivan1, C. Schmidt1, and J. Lee1 1

The Ohio State University,Columbus, OH

See page 141 for Poster floor plan

BMES 2014

151

Poster Session

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-199 Tri Partite Motif E3 Ubiquitin Ligase Family Proteins Role in Cancer Mechanics L. Volakis1, J. Alloush1, N. Weisleder2, and S. Ghadiali2 The Ohio State University, Columbus, OH, 2The Wexner Medical Center at The Ohio State University, Columbus, OH

1

)

P-Fri-162 Substratum Compliance Regulates Tetraploidy in Breast Cancer Cells A. Simi1, D. Radisky2, and C. Nelson1 1

Princeton University, Princeton, NJ, 2Mayo Clinic Cancer Center, Jacksonville, FL

P-Fri-200 Monitoring Protein Synthesis in Live Multiple Myeloma Cells

P-Fri-163 Tumor Activation Alters the Mechano-responsiveness, Capillary Formation, and Drug Sensitivity of Endothelial Cells in Synthetic Matrices

C. Tu1, Z. Smilansky2, N. Raje3,4, and J. Zoldan1

Y. Wu1, B. Guo1, and G. Ghosh2

1

University of Texas at Austin, Austin, TX, 2Anima Cell Metrology, Bernardsville, NJ, 3 Massachusetts General Hospital, Boston, MA, 4Harvard Medical School, Boston, MA

1

P-Fri-201 Individual CAR+ T cells Recycle Effector Functions by Conjugating to Multiple Tumor Cells

P-Fri-164 How Normal Breast Epithelial Cells Induce a Highly Protrusive and Invasive Phenotype in Breast Carcinoma Cells

N. Varadarajan1, I. Liadi1, H. Singh2, N. Rey-Villamizar1, G. Romain1, B. Roysam1, and L. Cooper2

1

University of Michigan Dearborn, Dearborn, MI, 2University of Michigan, Dearborn, Dearborn, MI

M. Lee1, P-H. Wu1, and D. Wirtz1

University of Houston, Houston, TX, 2UT MD Anderson Cancer Center, Houston, TX

1

P-Fri-202 Hyaluronic Acid Derived Fluorescent Imaging Agents with Tunable NIR Emission S. Kelkar1,2, T. Hill1,2, and A. Mohs1,2,3 Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, 2Wake Forest - Virginia Tech School of Biomedical Engineering and Sciences, Winston-Salem, NC, 3 Comprehensive Cancer Center of Wake Forest University, Winston-Salem, NC 1

P-Fri-203 Analysis of Single Cell Progenies of MDA-MB-231 Cells Reveals Prognostic Gene Signature for Breast Cancer Patients

P-Fri-165 Malignant Breast Tumor Cell Adhesion and Transmigration through Organspecific Microvascular Endothelium J. Fan1 and B. Fu1 1

Poster Session

Fri

Johns Hopkins University, Baltimore, MD

P-Fri-204 Irreversible Electroporation: Prostate and Pancreatic Cancer Cell Death Threshold Characterization A. Rolong1, K. Prokop1, P. Garcia1, C. Arena1, and R. Davalos1 1

Virginia Tech, Blacksburg, VA

P-Fri-205 Development of Novel Phase Change Electrodes with Metal Foams for Irreversible Electroporation Therapy K. Nithyanandam1 and R. Mahajan1 1

Virginia Tech, Blacksburg, VA

P-Fri-206 Improved Early Detection Of Ovarian Cancer Using Microfluidic Capture Of Circulating Tumor Cells M. Godla1, I. Cardle1, D. Gupta2, and B. Kirby1 1

Cornell University, Ithaca, NY, 2Weill Cornell Medical College, New York, NY

P-Fri-208 Enhanced Imaging of Breast Cancer Through Nanodiamonds L. Moore1,2, T. Towsend1, T. Meade1,2, and D. Ho3,4 Northwestern University, Evanston, IL, 2Northwestern University, Chicago, IL, 3UCLA School of Dentistry, Los Angeles, CA, 4UCLA, Los Angeles, CA

1

The City College of the City University of New York, New York, NY

P-Fri-166 Cancer Cell Migration in Response to Soluble Chemical Gradient and Micropatterned Surface Cues R. Natividad1 and A. Asthagiri1 1

P-H. Wu1, D. Gilkes1, J. Philips1, M-H. Lee1, and D. Wirtz1 1

Johns Hopkins University, Baltimore, MD

Northeastern University, Boston, MA

P-Fri-167 Effects of Glucose Concentration on Fibrillogenesis in Breast Epithelial Cells B. Martinez1, L. Griggs1, M. Zhao2, L. Elmore2, and C. Lemmon1 Virginia Commonwealth University, Richmond, VA, 2Virginia Commonwealth University Health System, Richmond, VA

1

P-Fri-168 cancelled by author P-Fri-169 The Role of Adhesive Interactions with Osteoblasts for Ex Vivo Maintenance of Patient Multiple Myeloma Cells W. Zhang1, J. Zilberberg2, Y. Gu1, Q. Sun1, P. Tolias1, and W. Lee1 Stevens Institute of Technology, Hoboken, NJ, 2Hackensack University Medical Center, Hackensack, NJ

1

P-Fri-171 MAP Kinase Drug Therapies Differentially Effect Melanoma Adhesion and the ECM During Metastasis B. Blehm1, Y. Kotobuki1, A. Afasizheva1, W. Vieira1, and K. Tanner1 1

National Institutes of Health, Bethesda, MD

P-Fri-172 Fibroblast Mediated Matrix Remodeling and Cancer Metastasis V. Shukla1, M. Schickel1, Z. Feliciano-Muniz1, and S. Ghadiali1,2 The Ohio State Univeristy, Columbus, OH, 2Wexner Medical Center at The Ohio State University, Columbus, OH

1

Track: Cancer Technologies

Tumor Microenvironment

P-Fri-173 Obesity-Associated Inflammation And Its Effect On Adipose Stromal Cells

Chairs: Edmond Young, Scott Verbridge

N. Springer1, B. Seo1, and C. Fischbach1

P-Fri-161 BRCA1 Repair Complexes in Hereditary Breast Cancer C. Winton1,2, B. Gilmore2, A. Demmert3, and D. Kelly1,2 1 3

Virginia Tech, Blacksburg, VA, 2Virginia Tech Carilion Research Institute, Roanoke, VA, Virginia Tech, Roanoke, VA

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

152

BMES 2014

1

Cornell University, Ithaca, NY

P-Fri-174 Investigating Breast Cancer Cell Behavior Using Tissue Engineering Scaffolds K. Guiro1 and T. Arinzeh1 1

New Jersey Institute of Technology, Newark, NJ

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-175 Endothelial Cell Invasion Dependency on Extracellular Matrix Microstructure and Geometry

P-Fri-406 Non-invasive Assessment of an Engineered Endothelium via Iron Oxide Nanoparticles and Magnetic Resonance Imaging

Y. Hosseini1, S. Verbridge1, and M. Agah1

B. Jiang1, D. Kats1, T. Meade1, and G. Ameer1

1

Virginia Tech, Blacksburg, VA

1

P-Fri-407 Mechanisms of Flow-dependent Endothelial COX-2 and PGI2 Expression

Track: Cardiovascular Engineering

S. Russell-Puleri1, E. Ebong2, and J. Tarbell1

Angiogenesis, Microvasculature and Lymphatics Chairs: Hyunjoon Kong, Keith Neeves

1

City College of New York, New York, NY, 2Northeastern University, Boston, MA

P-Fri-408 Microvascular Degeneration Predicted from Reduced Pulsatility S. Ahmed1, T. Bimal1, P. Nguyen1, E. Tuzun1, S. Coquis-Knezek1, and C. Quick1

P-Fri-397 Investigating the Role of Sphingosine-1-Phosphate and Hypoxia on Mature and Progenitor Endothelial Cells P. Williams1 and E. Silva1 University of California, Davis, Davis, CA

1

1

Michael E. DeBakey Institute, Texas A&M University, College Station, TX

P-Fri-409 Endothelial Cells are Influenced by Simvastatin Therapy when Exposed to Static and Laminar Flow Conditions M. Dick1,2, J-C. Tardif2, and R. Leask1,2

P-Fri-398 Large Scale Microscopy Reveals New Mechanisms of Angiogenesis U. Utzinger1, B. Baggett1, J. Weiss2, and J. Hoying3 1 University of Arizona, Tucson, AZ, 2University of Utah, Utah, UT, 3University of Louisville, Louisville, KY

P-Fri-399 Porous Microparticles for Cell Delivery in Tissue Regeneration A. Kuriakose1, J. Menon1, and K. Nguyen1 1

Northwestern University, Evanston, IL

University of Texas at Arlington, Arlington, TX

P-Fri-400 Urethane Doped Polyester (UPE) Based Nanoparticle Scaffolds for the Treatment of Peripheral Arterial Disease D. Thakore1, P. Punnakitikashem1, R. Tran2, J. Yang2, and K. Nguyen1

1

McGill University, Montreal, QC, Canada, 2Montreal Heart Institute, Montreal, QC, Canada

Track: Cardiovascular Engineering, Tissue Engineering

Cardiovascular Regeneration and Functional Restoration Chairs: Milica Radisic, Jun Liao P-Fri-366 A Thermo-Responsive, Self-Adhesive Injectable Scaffold for iPSC-Derived Cardiomyocyte Delivery

The University of Texas at Arlington, Arlington, TX, 2The Pennsylvania State University, University Park, PA

X. Wang1, L. Zhong1, Y. Chun1, C. Lim1, C. Hong1, S. Maltais1, and H-J. Sung1

P-Fri-401 Peristaltic Flow in the Glymphatic System

P-Fri-367 Mitochondrial Transfer From a Stem Cell to a Cardiomyocyte via Tunneling Nanotube

1

J. Grotberg1 and V. Suresh2 1

University of Michigan, Ann Arbor, MI, 2University of Auckland, Auckland, New Zealand

P-Fri-402 A Novel Approach to Study Contraction-Induced Relaxation in Lymphatic Vessels A. Rosales1, F. Yu1, Y. Thakker1, T. Lam1, T. Hood1, C. Quick1, and R. Dongaonkar1 1

Michael E. DeBakey Institute, Texas A&M University, College Station, TX

P-Fri-403 Filariasis Millifluidic Platform for Minimizing Blood Volume During Mosquito Feeding T. Spencer , A. Moorhead , and B. Dixon 1

2

Georgia Institute of Technology, Atlanta, GA, 2UGA College of Veterinary Medicine, Athens, GA

P-Fri-404 Characterizing the Simultaneous Effects of Shear Stress and Transmural Pressure on Lymphatic Pumping H. Pariseau1, D. Dang1, J. White1, C. Quick1, and R. Dongaonkar1 Michael E. DeBakey Institute, Texas A&M University, College Station, TX

P-Fri-405 Calcium Oscillations and Waves in Vascular Cells: Mechanisms of Initiation and Modulation J. Parikh1, A. Kapela1, and N. Tsoukias1 1

Florida International University, Miami, FL

Vanderbilt University, Nashville, TN

H. Yang1, R. Runyan2, T. Borg3, R. Markwald3, and B. Gao1 Clemson University, Clemson, SC, 2University of Arizona, Tucson, AZ, 3Medical University of South Carolina, Charleston, SC

1

P-Fri-368 Engineered Cell Therapy with Embryonic Stem Cell-derived Cardiomyocytes Encapsulated in Injectable Nanomatrix Gel Enhanced Engraftment and Promoted Cardiac Repair in Experimental Myocardial Infarction K. Ban1, H-J. Park1,2, S. Kim1, A. Andukuri1, H-W. Jun3, and Y-S. Yoon1 1 3

1

1

1

1

Emory University, Atlanta, GA, 2The Catholic University, Seoul, Korea, Republic of, University of Alabama, Birmingham, AL

P-Fri-369 Wireless Electrical Signal Recording for Neonatal Mouse Model of Heart Regeneration T. Beebe1, Y. Zhao2, H. Cao3, H. Zhang4, X. Zhang2, H. Chang4, C-L. Lien5, Y-C. Tai2, and T. Hsiai1,3 UCLA School of Engineering & Applied Sciences, Los Angeles, CA, 2California Institute of Technology, Pasadena, CA, 3UCLA School of Medicine, Los Angeles, CA, 4Northwestern Polytechnical University, Xi'an, China, People's Republic of, 5Children's Hospital Los Angeles, Los Angeles, CA 1

P-Fri-370 Differentiation of Human Progenitor Cells on Decellularized Cardiac Tissue R. Thibault1, E. Chau1, A. Gordon2, A. Gobin1, M. Resende1, R. Schwartz1, and D. Taylor1 1

Texas Heart Institute, Houston, TX, 2Rice University, Houston, TX

See page 141 for Poster floor plan

BMES 2014

153

Poster Session

Fri

Friday | october 24 | 2014

Poster Session Fri 9:30am – 5:00pm   Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM

P-Fri-371 An Injectable Hydrogel with bFGF Release to Augment Cardiospherederived Cell Survive and Angiogenesis Under Ischemic Conditions

P-Fri-381 3D Printed Heart Models and Their Potential in Heart Surgery

X. Li1, Z. Fan1, M. Fu1, Y. Xu1, and J. Guan1

1

1

Ohio State University, Columbus, OH

P-Fri-372 Investigation of Drug-Induced Congenital Heart Defects Using Human Pluripotent Stem Cell Derived Cardiomyocytes C. Rigdon1, P. Kerscher1, and E. Lipke1 1

University of Pittsburgh Department of Bioengineering, Pittsburgh, PA, McGowan Institute for Regenerative Medicine, Pittsburgh, PA, 3Children's Hospital of Pittsburgh, Pittsburgh, PA, 4Launchpoint Technologies, Goleta, CA, 5Carnegie Mellon University Department of Biomedical Engineering, Pittsburgh, PA

1

2

P-Fri-374 Total Artificial Heart and Mock Circulation System: A Training Tool for Ventricular Assist Devices K. DeCook1, J. Gamboa1, P. Tran1, R. Smith1, D. Burkhoff2, and M. Slepian1 University of Arizona, Tucson, AZ, 2Columbia University, New York, NY

P-Fri-375 Prohealing Multifunctional Endothelium Nanomatrix Coated Stents G. Alexander1, A. Andukuri1, Y-D. Sohn2, Y-S. Yoon2, B. Brott1, P. Anderson1, and H-W. Jun1 1

Fri

P-Fri-382 Efficiency of Protease-Activatable Viruses for Cardiovascular Disease Tuned via Incorporation of Wild-type Capsid Subunits M. Ho1, M. Lam1, M. Yamagami1, and J. Suh1 1

S. Olia1,2, V. Shankarraman2, T. Maul1,2,3, E. Kocyildirim2, S. Snyder4, J. Verkaik4, D. Paden4, W. Wagner1,2, J. Antaki2,5, M. Kameneva1,2, P. Wearden2,3, and H. Borovetz1,2

Poster Session

University of South Florida, Tampa, FL

Rice University, Houston, TX

Auburn University, Auburn University, AL

P-Fri-373 Preclinical Performance of the PediaFlow® Pediatric VAD - A Potential Breakthrough Clinical Device

1

K. Das1 and H. Chittam1

University of Alabama at Birmingham, Birmingham, AL, 2Emory University, Atlanta, GA

P-Fri-376 Cardiovascular Assist Device Shear Stresses Induce Pro-thrombotic Microparticle Formation A. Meyer1, R. Kamucheka1, P. Nair2, K. Reddoch2,3, R. Montgomery3, B. Parida3, A. Cap3, N. Mackman4, and A. Ramasubramanian2 UT Health Science Center, San Antonio, TX, 2UT San Antonio, San Antonio, TX, 3U.S. Army Institute of Surgical Research, San Antonio, TX, 4University of North Carolina, Chapel Hill, NC 1

Track: Cardiovascular Engineering

Heart Valves and Stents Chairs: Aaron Baker, Craig Goergen

)

P-Fri-383 Effects Of Short-term Exposure of Estrogen On Smooth Muscle Cells Proliferation J. Betala1, J. Lee 1, E. Langan2, and M. LaBerge1 1

Clemson University, Clemson, SC, 2Greenville hospital system, Greenville, SC

P-Fri-384 Hydroxyapatite Nanoparticles Enhance Osteoblastic Differentiation of Valvular Interstitial Cells in 3D Culture J. Richards1, J. Russ1, L. Estroff1, and J. Butcher1 1

Cornell University, Ithaca, NY

P-Fri-385 Nutrient Transport During Engineered Heart Valve Tissue Exposure to Steady Flow M. Salinas1, V. Unnikrishnan2, and S. Ramaswamy1 1

Florida International University, Miami, FL, 2The University of Alabama, Tuscaloosa, AL

P-Fri-386 Aortic Valve Endothelial to Mesenchymal Transformation is Induced by Altered Extracellular Matrix Composition S. Dahal1 and G. Mahler1 1

Binghamton University, Binghamton, NY

P-Fri-377 Potential Thrombogenic Impacts of the Radial Orientations of Inflow and Outflow Cannulae with Respect to the HeartMate II VAD

P-Fri-387 Porcine Pericardium As A Biomaterial For Bioprosthetic Venous Valves

W-C. Chiu1, S. Einav1, A. McLarty1, M. Slepian1,2, and D. Bluestein1

1

1

Stony Brook University, Stony Brook, NY, 2University of Arizona, Tucson, AZ

P-Fri-378 Reynolds Stress Assessment in the LVAD-Assisted Heart using High-Speed PIV M. Razaz Zadeh1, A. Falahatpisheh2, A. Kheradvar2, and K. May-Newman1 1

San Diego State University, San Diego, CA, 2University of California, Irvine, Irvine, CA

P-Fri-379 Effect of Environmental Dynamics on Bioresorbable Vascular Scaffold Performance J. Ferdous1, V. Kolachalama2, N. Fatematuzzahan1, and T. Shazly1 University of South Carolina, Columbia, SC, 2Charles Stark Draper Laboratory, Cambridge, MA

1

P-Fri-380 Comparison of Blood Damage Indices in a Heart Assist Device Using CFD with Different Flow Models M. Heck1, T. Snyder2, D. Papavassiliou1, E. O'Rear1, and D. Schmidtke1 1

University of Oklahoma, Norman, OK, 2VADovations, Inc., Norman, OK

L. Maganini1 and N. Vyavahare1 Clemson University, Clemson, SC

P-Fri-388 Valve Interstitial Cell Remodeling Under Abnormal Mechanical Stress Is Mediated By 5HT and FGF2 Signaling N. Lam1, J. Carradini1, S. Sharma2, and K. Balachandran1 University of Arkansas, Fayetteville, AR, 2University of Arkansas for Medical Sciences, Little Rock, AR

1

P-Fri-389 Coaxially Electrospun Biohydrid Nanofibrous Scaffolds for Vascular Regeneration N. Nagiah1 and W. Tan1 1

University of Colorado, Boulder, CO

P-Fri-390 Properties of Graphene-Silicone Prosthetic Heart Valves M. Lordeus1, A. Estrada1, D. Stewart1, R. Dua1, C. Zhang1, A. Agarwal2, and S. Ramaswamy1 1

Florida International University, Miami, FL, 2Indian Institute of Technology, New Delhi, India

P-Fri-391 Novel Magnesium-based Stent Biomaterials with Anticorrosion and Drugeluting Coatings J. Ma1, N. Zhao1, and D. Zhu1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

154

BMES 2014

North Carolina A&T State University, Greensboro, NC

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-392 Effective Gene Delivery to Heart Valve Cells Using Adeno-associated Virus F. Wong1, M. Ho1, J. Suh1, and J. Grande-Allen1 1

J. Parikh1, A. Kapela1, and N. Tsoukias1

Rice University, Houston, TX

P-Fri-393 Pharmacokinetic Evaluation of Non-Stent Drug Delivery: An In Vitro System For Rapid Evaluation M. Atigh1 and S. Yazdani1 1

A. Basu1 and Z. He1

A. Khanna1, I. Luzinov1, F. Vatansever1, E. Langan III2, and M. LaBerge1 Clemson University, Clemson, SC, 2Greenville Health System, Greenville, SC

P-Fri-396 Design of an Echocardiographic Benchtop Testing Phantom Replicating Tricuspid Regurgitation (TR) H. O' Grady1, M. Gilmore2, and P. Delassus1 1 Galway Mayo Institute of Technology (GMIT), Galway, Ireland, 24TECH Cardio Ltd., Galway, Ireland

P-Fri-563 Dynamic Models of Cerebral Hemodynamics used for Diagnosis of Alzheimer's Disease University of Southern California, Los Angeles, CA, 2Radboud University, Nijmegen Medical Center, Nijmegen, Netherlands, 3University of Texas, Southwestern Medical Center, Dallas, TX

1

P. Theriot1, G. Osa1, T. Dunn1, S. Wallooppillai1, M. Mohuiddin1, and C. Quick1 1

Track: Cardiovascular Engineering, Biomechanics

M. Thirugnanasambandam1 and E. Finol1 1

P-Fri-566 Increasing Differential Sensitivity to Preload and Afterload of LVADs Operated in Pulsatile Mode M. McDowall1, A. Workman1, H. Adeleke 1, O. Sarwar1, S. Coquis-Knezek1, and C. Quick1

)

P-Fri-557 Evaluation of the Time Course of Aortic Aneurysm Residual Stress in Apolipoprotein E-deficient Mice R. Peattie1, C. Kahn2, Y. Zhang1, J. Galper1, and L. Dorfmann2 Tufts Medical Center, Boston, MA, 2Tufts University, Medford, MA

)

P-Fri-558 Maximum Circumference Detects Nonhomogeneous Sac ExpansionIn Abdominal Aortic Aneurysm R. S. Nomoto1, M. Iafrati2, L. Dorfmann3, and R. Peattie2 1 Tufts University, Boston, MA, 2Tufts Medical Center, Boston, MA, 3Tufts University, Medford, MA

P-Fri-559 Feasibility of Pulsatile Flow in Ex Vivo Lung Perfusion University of Louisville, Louisville, KY

P-Fri-560 Integrating Biomechanics and Mechanobiology to Predict Cardiac Contractility in a Closed-Loop System C. Nwokocha1, J. Schueler1, M. Villarreal1, D. Westra1, T. Duong1, C. Quick1, and R. Stewart1 Michael E. DeBakey Institute, Texas A&M University, College Station, TX

P-Fri-561 Cardiovascular Mechanical Properties Affect Regression of the Ductus Arteriosus H. Ahmed , F. Hise , U. Chikhliya , C. Quick , and R. Stewart 1

1

1

1

The University of Oklahoma, Norman, OK, 2Advanced Cardiac Care, INTEGRIS Baptist Medical Center, Oklahoma city, Oklahoma, OK

1

P-Fri-568 Design and Calibration of Transducers for Aortic Root Force Measurement T. Bechsgaard1,2, S. Laugesen2, J. Honge2, H. Nygaard2, S. Nielsen2, and P. Johansen1,2 1

Aarhus University, Aarhus N, Denmark, 2Aarhus University Hospital, Aarhus N, Denmark

P-Fri-569 Elevated Arterial Wall Permeability May Cause Vulnerable Plaque Formation In Mice Z. Mohri1, E. Rowland2, L. Clarke2, A. De Luca2, V. Peiffer2, S. Sherwin2, R. Krams2, and P. Weinberg2 Imperial College London, London, United Kingdom, 2Imperial College London, Lonodn, United Kingdom

1

P-Fri-570 Renal Blood Flow Distribution Assayed by Indicator-Dilution Method and Morphometric Model Analysis. J. Bukowy1, L. Evans1, A. Cowley1, and D. Beard2

K. Zoeller1, E. Schumer1, P. Linsky1, M. Sobieski II1, G. Monreal1, K. Soucy1, G. Giridharan1, S. Koenig1, M. Slaughter1, and V. van Berkel1

1

Michael E. DeBakey Institute, Texas A&M University, College Station, TX

Q. Nguyen1, E. O' Rear1, D. Schmidtke1, D. Papavassiliou1, and T. Snyder2

Chairs: Eno Ebong, Danial Shahmirzadi

1

University of Texas at San Antonio, San Antonio, TX

P-Fri-567 Effects Of Hemodynamic Factors On Hemolysis In Shear Flows

Hemodynamics, Vascular Mechanics and Flow Modelling

1

Michael E. DeBakey Institute, Texas A&M University, College Station, TX

P-Fri-565 Survival Analysis for Estimating Abdominal Aortic Aneurysm Rupture

1

1

Florida International University, Miami, FL

P-Fri-564 Assumed Pressure Pulse Augmentation Can Originate from the Heart

Texas Tech University, Lubbock, TX

P-Fri-395 Fabrication Of Human Serum Albumin Nanofilm For Enhanced Hemocompatibility And Vascular Smooth Muscle Cell Response 1

1

Y. Kang1, D. Shin1, J. Claassen2, R. Zhang3, and V. Marmarelis1

University of South Alabama, Mobile, AL

P-Fri-394 Tricuspid Valve Leaflet Force on the Annulus after Clover Repair 1

P-Fri-562 Regulation of Vascular Tone via Localized Calcium Signaling in Myoendothelial Projections

1

Michael E. DeBakey Institute, Texas A&M University, College Station, TX

1

Medical College of Wisconsin, Milwaukee, WI, 2University of Michigan, Ann Arbor, MI

P-Fri-571 The Structural Determinants of Hemostatic Thrombi J. Welsh1, T. Stalker1, L. Brass1, and S. Diamond1 1

University of Pennsylvania, Philadelphia, PA

P-Fri-572 A Quantitative Test of the Efficient Transport Network Hypothesis in the Cerebral Vasculature D. Kudlik1 and P. Drew1 1

Pennsylvania State University, University Park, PA

P-Fri-573 Modeling Compensatory Mechanisms to Maintain Homeostasis During Moderate Blood Loss M. Wu1, Y. Tong1, K. Dupree1, T. Stiles1, and C. Quick1 1

Michael E. DeBakey Institute, Texas A&M University, College Station, TX

See page 141 for Poster floor plan

BMES 2014

155

Poster Session

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-574 A Novel Approach to Modeling Acute Normovolemic Hemodilution

)

P-Fri-585 Effect of Sleep Apnea Event Duration on Concomitant Rise in Blood Pressure and Cerebral Blood Flow

B. Pliskow1 and M. Kaya1 1

Florida Institute of Technology, Melbourne, FL

P-Fri-575 Simple Analytical Model to Predict Critical Hemodynamic Parameters in Fontan Patients O. Okose1, M. Shimazaki1, J. Nguyen1, K. McFadden1, M. Mohuiddin1, and C. Quick1 1

Michael E. DeBakey Institute, Texas A&M University, College Station, TX

P-Fri-576 Novel Approach to Optimize both Simplicity and Accuracy when Simplifying Complex Algebraic Models C. Mason1, W. Wilder1, A. Wilkerson1, A. Garcia1, M. Mohuiddin1, R. Stewart1, and C. Quick1 1

Michael E. DeBakey Institute, Texas A&M University, College Station, TX

P-Fri-586 Melding Experimental Protocol and Mathematical Representation in the Fürth-Ornstein-Taylor Equation E. Eckstein1, M. Leggas2, B. Ma3, J. Lavine4, and J. Goldstein1 1 University of Memphis, Memphis, TN, 2University of Kentucky, Lexington, KY, 3University of Vermont, Burlington, VT, 4Bunker Hill Community College, Charlestown, MA

Track: Cellular and Molecular Bioengineering

Immunoengineering and Extracellular Matrix Interactions

A. Morfin1, F. Dalal1, S. Kamp1, A. Armstrong1, M. Richter1, T. Stiles1, and C. Quick1

Chairs: Kent Leach, Hanjoong Jo

Michael E. DeBakey Institute, Texas A&M University, College Station, TX

P-Fri-578 Patient-specific Computational Fluid Dynamic Modelling of Pulmonary Artery Stenosis M. Dong , E. Kung , J. Feinstein , and A. Marsden 1

1

2

1

University of California, San Diego, La Jolla, CA, Stanford University, Stanford, CA

1

2

V. Flamini1, S. Gallot Lavallee1,2, S. Maddalo3, A. DeAnda3, and B. Griffith3,4 New York University, Brooklyn, NY, La Sapienza, Universita; di Roma, Rome, Italy, New York University, New York, NY, 4University of North Carolina, Chapel Hill, Chapel Hill, NC 1

2

P-Fri-49 Design and Selection of an MBP-Specific T-Cell Receptor in order to Abrogate Autoreactive Immune Attack in Multiple Sclerosis E. Leonard1, K. Entzminger1, J. Fogarty1, B. Roy1, and J. Maynard1 1

University of Texas at Austin, Austin, TX

P-Fri-50 High Fc Density Particles Result in Binary Complement Activation but Tunable Macrophage Phagocytosis

P-Fri-579 Patient Specific Models of Aortic Dissection

Fri

UT Arlington, Arlington, TX, 2Sleep Consultants, Ft. Worth, TX, 3Sleep Consultants, Fort Worth, TX, 4UT Southwestern Medical Center Dallas, Dallas, TX

1

P-Fri-577 Mechanical Determinants of Acceptable Blood Volume Ranges in Heart Failure Patients 1

Poster Session

S. Manchikatla1, R. Alex1, D. Watenpaugh2,3, R. Zhang4, E. Altuwaijri1, and K. Behbehani1

3

P-Fri-580 The Effect of Vascular Curvature on Blood Flow and Oxygen Transport in Arterio-Venous Fistulae

T. Sulchek1, P. Pacheco1, C. Pantoja1, A. Mylarapu1, and D. White2 1

Georgia Tech, Atlanta, GA, 2USDA, Ames, GA

P-Fri-51 Accurate and Quantitative Immune Repertoire Sequencing using Unique Molecular Identifiers N. Jiang1, D. Wu1, M. Qu1, and B. Wendel1

L. Grechy , F. Iori , R. Corbett , W. Gedroyc , N. Duncan , C. Caro , and P. Vincent1

1

Imperial College London, London, United Kingdom, St Mary Hospital, London, United Kingdom

P-Fri-52 Sinusoidal Wavy Surfaces for Curvature-guided Migration of T Lymphocytes

P-Fri-581 Stiffening Right Ventricle Helps Relieving Respiratory Failure After Acute Kidney Injury (AKI)

K. Song1, S. Park1, D. Kim1, and J. Doh1

1

1

1

2

1

1

1

2

Z. Meng1, H. Crawford1, L. Tufts1, C. Hahn1, S. Johnson1, and B. Poskevich1 1

Michael E. DeBakey Institute, Texas A&M University, College Station, TX



E. Bartolak-Suki1 and B. Suki1

Clemson University, clemson, SC

G. Drzewiecki , G. Sathish Krishna , and H. Katta Rutgers University, Piscataway, NJ

3

P-Fri-55 Dynamic Micropatterning of Cells on Nanostructured Surfaces Using a Cell-friendly Photoresist

1

1

1

)

156

BMES 2014

POSTECH, pohang, Korea, Republic of

P-Fri-56 Connexin43 Mimetic Peptides for use in Breast Reconstructive Scar Reduction K. Degen1, M. Rhett2, M. Yost2, K. Moyer3, and R. Gourdie1,4 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

University of Connecticut, Storrs, CT, 2St. Jude Children’s Research Hospital, Memphis, TN, University of Connecticut Health Center, Farmington, CT

S. Kweon1, K. Song1, J. Choi1, and J. Doh1

P-Fri-584 Force Derived Applanation Tonometry for High and Low Deflections In a Phantom Vessel 1

Duke University, Durham, NC

P-Fri-54 Single-cell Force Spectroscopy as a Technique to Quantify Erythrocyte Cytoadhesion and Biochemical Modulation 1

P. Nahar1, N. Gohad1, and N. Vyavahare1

1

J. Fu1, T. Cheung1, and G. Truskey1

J. Maciaszek1,2, K. Partola1, B. Andemariam3, and G. Lykotrafitis1

Boston University, Boston, MA

P-Fri-583 Mechanisms of Phenotypic Change of Vascular Smooth Muscle Cells to Osteoblast Like Cells in Vascular Calcification 1

POSTECH, Pohang, Korea, Republic of

P-Fri-53 Substrate Stiffness Promotes Endothelial Senescence 1

P-Fri-582 Regulation of ATP and ROS Production by Stretch Fluctuations in Vascular Smooth Muscle Cells 1

1

The University of Texas at Austin, AUSTIN, TX

3

Virginia Tech, Blacksburg, VA, 2Medical University of South Carolina, Charleston, SC, Carilion Clinic, Roanoke, VA, 4Virginia Tech Carilion Research Institute, Roanoke, VA

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-57 The Induction of EMT In Correlation With The Secretion of LTBP-1 In Mammary Epithelial Cells

P-Fri-275 Green and Black Tea Polyphenols Mechanistically Inhibit Amyloid-β Aggregation in Alzheimer's Disease

R. Malik1, L. Griggs1, and C. Lemmon1

S. Chastain1, K. Pate1, and M. Moss1

1

Virginia Commonwealth University, Richmond, VA

1

University of South Carolina, Columbia, SC

P-Fri-58 Embolism Coil Geometry Modulates Cell-Matrix Interactions

P-Fri-276 RNA Enzymes as Potential Tools for Artificial Gene Regulation

B. Earnest1, E. Nagel1, A. Evans1, and B. Helmke1

R. Poudyal1, M. Callaway1, and D. Burke1

1

University of Virginia, Charlottesville, VA

1

University of Missouri, Columbia, MO

P-Fri-59 PMEDSAH is a Polyzwitterionic, Non-fouling Material that Supports Pluripotent Cell Growth

P-Fri-277 Quantitative Profiling of Angiogenic Receptors on Human Dermal Fibroblasts

T. Aydin1, L. Villa1, R. Kumar1, J. Lahann1, and P. Krebsbach1

S. Chen1 and P. Imoukhuede1

1

University of Michigan, Ann Arbor, MI

1

University of Illinois at Urbana-Champaign, Champaign, IL

P-Fri-60 Sphingolipid Dysregulation Initiates Myeloid Cell Activation in Sickle Cell Disease

P-Fri-278 Intracellular Delivery of Macromolecules Using Ultrahigh Frequency Ultrasound

A. Lane1, A. Awojoodu1, Y. Zhang1, and E. Botchwey1

S. Yoon1, M. Kim1, N. Cabrera-Munoz1, H. Kim1, and K. Shung1

1

Georgia Institute of Technology, Atlanta, GA

1

University of Southern California, Los Angeles, CA

P-Fri-61 Exogenous Delivery of Indoleamine 2,3 Dioxygenase for the Induction of Tolerance

P-Fri-279 Engineering Quorum-sensing Crosstalk to Generate Complex Responses of Synthetic Gene Networks

E. Bracho-Sanchez1, J. Lewis1, and B. Keselowsky1

F. Wu1, D. Menn1, and X. Wang1

1

University of Florida, Gainesville, FL

1

Arizona State University, Tempe, AZ

P-Fri-62 A Microwell System for Detection of Cytokines Secreted by Single Adherent Macrophages

P-Fri-280 Tuning Molecular Self-Assembly by Leveraging Synthetic Biology to Optimize Biomedical Materials

F. McWhorter1 and W. Liu1

R. Zhang1 and W. Ruder1

1

University of California, Irvine, Irvine, CA

1

Track: Cellular and Molecular Bioengineering, Bioinformatics, Computational and Systems Biology

Molecular Bioengineering, Systems and Synthetic Biology

Virginia Tech, blacksburg, VA

P-Fri-281 Spatial Segregation of Synthetic Biological Circuit Output using Dropletbased Microfluidics S-H. Paek1 and W. Ruder1 1

Virginia Tech, Blacksburg, VA

P-Fri-282 Aglycosylated Antibody Engineering for Novel Effector Functions T. Kang1, S. Jung2, W. Kelton1, and G. Georgiou1 The University of Texas at Austin, Austin, TX, 2Kookmin University, Seoul, Korea, Republic of

1

Chairs: B. Rita Alevriadou, Stacey Finley P-Fri-272 A Small Molecule-Peptide Hybrid Screening Technique Using Selenocysteine Phage Display J. Beech1, H. Figler1, J. Linden2, C. Noren3, L. Saleh3, and K. Kelly1 University of Virginia, Charlottesville, VA, 2La Jolla Institute, La Jolla, CA, 3New England Biolabs, Ipswich, MA

1

P-Fri-273 Scaffold Residues of Monobody-Maltose Binding Protein 74 (MBP74) are Critical for Binding with its Ligand D. Shea1, L-L. Cheung1,2,3, N. Nicholes1, A. Date1, M. Ostermeier1,2, and K. Konstantopoulos1,2,3,4 Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD, 2Johns Hopkins Institute for NanoBioTechnology, Baltimore, MD, 3Johns Hopkins Physical Sciences-Oncology Center, Baltimore, MD, 4Johns Hopkins Center of Cancer Nanotechnology Excellence, Baltimore, MD 1

P-Fri-274 Characterization Of Autocatalytic Activation Of Influenza Hemagglutinin M. Valverde1, M. Baltz2, J. Price3, J. Lee4, and E. Boder1 1 University of Tennessee, Knoxville, TN, 2Cornell University, Ithaca, NY, 3University of Delaware, Newark, DE, 4MedImmune, Inc., Gaithersburg, MD

P-Fri-283 Creation of CTX-M-14/CTX-M-15 Gene Fusions to Localize CTX-M-15 Associated Upregulation Element A. Varman1 and C. Geyer2 1

Duchesne Academy, Omaha, NE, 2Creighton University, Omaha, NE

P-Fri-284 Resveratrol And Its Derivatives’ As Potential Inhibitors Of Aβ Peptides Aggregation Y. Wang1 and M. Moss1 1

University of South Carolina, Columbia, SC

P-Fri-285 Pathophysiological Mechanisms of Autism and Identification of Therapeutic Targets M. Hwang1, H. Cho1, and Y. Lee1 1

Virginia Tech, Blacksburg, VA

P-Fri-286 Modeling the Effects of a Microfluidic Environment on GFP Expression in Reporter Bacteria C. Austin1, W. Stoy1, P. Su2, M. Harber1, P. Bardill1, B. Hammer1, and C. Forest1 1

Georgia Institute of Technology, Atlanta, GA, 2University of California, Berkeley, CA

See page 141 for Poster floor plan

BMES 2014

157

Poster Session

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-287 An Optogenetic System for Spatiotemporal Regulation of Viral Gene Delivery Vectors

P-Fri-447 Tamoxifen-Coated Selenium Nanoparticles for Breast Cancer Treatment

E. Gomez1, K. Gerhardt1, J. Judd1, J. Tabor1, and J. Suh1

1

1

Rice University, Houston, TX

P-Fri-288 Engineering Diagnostic and Therapeutic Proteins Targeting the MSLNMUC16 Tumor Biomarker Interface S. Moore1, F. Bassir1, K. George1, and A. Sirois1 1

Smith College, Northampton, MA

C. Krueger1, T. Cradick1, and G. Bao1 Georgia Institute of Technology, Atlanta, GA

P-Fri-290 Engineered Aglycosylated IgG Variants with Enhanced Anti-tumor Activity via Complement Dependent Cytotoxicity (CDC) withoutAntibody Dependent Cell Cytotoxicity (ADCC). C-H. Lee1, J. Lee1, T. Kang1, and G. Georgiou1 1

University of Texas at Austin, Austin, TX

Northeastern University, Boston, MA

P-Fri-448 Crosslinking Albumin To Alter Curcumin Release From Spray Dried Particles I. Jain1, M. Kelecy1, M. O'Toole1, R. Keynton1, A. Gobin2, and P. Soucy1 1

P-Fri-289 Knockdown of NHEJ-Related Genes Increases Rate of Homologous Recombination for Genome Editing 1

M. Stolzoff1, A. D'Antonio1, and T. Webster1

University of Louisville, Louisville, KY, 2Texas Heart Institute, Houston, TX

P-Fri-449 Synthesis of Dendrimer-Camptothecin Nanoconjugates via Click Chemistry O. Zolotarskaya1, H. Yang1, L. Xu1, and K. Valerie1 1

Virginia Commonwealth University, Richmond, VA

P-Fri-450 A Theoretical Model on the Acoustic Vaporization of Dual Phase Microdroplets D. Li1, M. Fabiillii1, J. Fowlkes1, P. Carson1, and J. Bull1 1

University of Michigan, Ann Arbor, MI

)

P-Fri-451 The Combinatorial Effect of Multiple MicroRNA Delivery on Glioblastoma Multiforme Y. Yin1, D. Rassias1, A. Beliveau1, and A. Jain1

Track: Drug Delivery

1

Drug Delivery Chairs: Jianjun Guan, Jennifer Kang-Mieler P-Fri-441 Developing an Albumin Binding Peptide Derivative of Anticancer Therapeutics Poster Session

Fri

Y-R. Ahn1 1

Duke University, Durham, NC

P-Fri-442 Early Black Cranberry Proanthocyanidins Inhibit Melanoma Cell Growth and Proliferation N. Macedo1, T. Ferreira1, C. Neto1, and S. Bhowmick1 1

UMass Dartmouth, Dartmouth, MA

P-Fri-443 Early Development of Gold-Lipidic Nanocomposites for the Detection and Treatment of Prostate Cancer C. Dobson1, C. Pickering1, M. Eggert1, A. David1, P. Panizzi1, and R. Arnold1 1

Auburn University, Auburn, AL

P-Fri-444 Development of a Nanoparticle Formulation of Orlistat: Solubility, Stability, and Cytotoxicity T. Hill , , F. Wheeler , S. Kelkar , , S. Kridel , and A. Mohs , , 1 2

3

1 2

3

Worcester Polytechnic Institute, Worcester, MA

P-Fri-452 Multifunctional Polymeric Nanoconstructs for Magnetic Resonance Imaging and Combinatorial Treatment of Brain Tumors

1 2 3

Wake Forest-Virginia Tech School of Biomedical Engineering and Sciences, Winston Salem, NC, 2Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, 3 Comprehensive Cancer Center of Wake Forest University, Winston Salem, NC 1

C. Stigliano1, M. Cho1, M. Ramirez1, S. Aryal1, and P. Decuzzi1 1

Houston Methodist Research Institute, Houston, TX

P-Fri-453 Curcumin Loaded Polymeric Nanoparticles For The Prevention Of Metastatic Disease A. Palange1,2, D. Di Mascolo 1,2, and P. Decuzzi1 Houston Methodist Research Institute, Houston, TX, 2University of Magna Graecia, Catanzaro, Italy

1

P-Fri-454 Development of pH Sensitive Micelles for Drug Delivery to Advanced Prostate Cancer O. Aydin1, I. Youssef1,2, Y. Durmaz1, G. Tiruchinapally1, and M. ElSayed1 1

University of Michigan, Ann Arbor, MI, 2Mansoura University, Mansoura, Egypt

P-Fri-455 Mild Hypethermia Enhances Transport of Liposomal Gemcitabine and Improves In vivo Therapeutic Response Mild Hyperthermia Enhances Transport of Liposomal Gemcitabine and Improves In Vivo Therapeutic Response D. Kirui1, C. Celia2, R. Molinaro1, H. Shen1, M. Ferrari1, and D. Kirui1 1

Houston Methodist Research Institute, Houston, TX, 2University of Chieti, Chieti, Italy

P-Fri-456 cancelled by author

P-Fri-445 Reducing Cell Survival in Metastatic Breast Cancer Using Curcumin-Loaded Silk Fibroin Nanoparticles

P-Fri-457 Nanoformulations of PARP Inhibitors for the Treatment of Cancer

D. Mishra1, T. Iyyanki1, and A. Mathur1

1

1

M.D. Anderson Cancer Center, Houston, TX

P-Fri-446 Temperature- and pH-responsive Photoluminescent Nanoparticles for Lung Cancer Treatment J. Menon1,2, D. Nguyen1,2, M. Wei1,2, B. Yuan1,2, J. Yang3, and K. Nguyen1,2 University of Texas at Arlington, Arlington, TX, 2University of Texas Southwestern Medical Center, Dallas, TX, 3Pennsylvania State University, University Park, PA

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

158

BMES 2014

P. Baldwin1, S. Tangutoori1, J. Shelke1, and S. Sridhar1 Northeastern University, Boston, MA

P-Fri-458 Localized Tumor Delivery of Radiosensitizers and Chemotherapeutics Using INCeRT Implants J. Belz1, R. Kumar1, S. Markovic1, Y. Sun1, M. Niedre1, M. Makrigiorgos2, R. Cormack2, and S. Sridhar1 Northeastern University, Boston, MA, 2Dana Farber Cancer Institute, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

1

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM

)

P-Fri-459 Injectable Gelatin Derivative Hydrogels with Sustained VEGF Release for Induced Angiogenesis Z. Li1, S. Li2, and X. Liu1 Department of Biomedical Sciences, Texas A&M University Baylor College of Dentistry, dallas, TX, 2Department of Plastic and Aesthetic Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China, People's Republic of

1

)

P-Fri-460 Drug-delivery Surgical Suture for Reduction of Scar Formation. S. Choi1, B. Kim2, M. Park1, C. Park1, S. Lee1, C. Heo3, and Y. Choy1,2,4 Interdisiplinary Program in Bioengineering, College of Engineering, Seoul National University, Seoul, Korea, Republic of, 2Department of Biomedical Engineering, Seoul National University, Seoul, Korea, Republic of, 3Department of Plastic Surgery and Reconstructive Surgery, Seoul National University College of Medicinety, Seoul, Korea, Republic of, 4Institute of Medical & Biological Engineering, Medical Research Center, Seoul National University, Seoul, Korea, Republic of

1

P-Fri-470 NanoPorous Polycaprolactone Thin Films for Zero-order Protein Release E. Schlesinger1 and T. Desai2 UC Berkeley - UCSF, San Francisco, CA, 2University of California, San Francisco, San Francisco, CA

1

P-Fri-471 Encapsulation of Halloysite Clay Nanotubes with Drug Impregnated Nanolayers D. Mills1 and R. Grimes1 1

Louisiana Tech University, Ruston, LA

P-Fri-472 Light-Mediated Multi-Step Release From Liposomes J. Park1, R. Stowers1, and L. Suggs1 1

University of Texas at Austin, Austin, TX

P-Fri-461 Enhancing Macrophage Recruitment by Controlling Scaffold Pore size

P-Fri-473 Cross-linked Lipid Particles for Delivery of Antiretroviral Combinations to Inhibit HIV Infection

Y-H. Kim1 and Y. Tabata1

W. Lykins1, R. Ramanathan1, Y. Jiang1, and K. Woodrow1

1

Institution of Frontier Medical Science, Kyoto University, Kyoto, Japan

P-Fri-462 Multi-layered Polymeric Microparticles For Sustained Drug Delivery J. Castillo1, L. Gaviria1, T. Guda1, and J. Ong1 1

University of Texas at San Antonio, San Antonio, TX

P-Fri-463 Solvent-free Fabrication of polyHIPE Microspheres for Controlled Release of Growth Factors M. Whitely1, R. Moglia1, M. Brooks1, J. Robinson1, M. Pishko1, and E. CosgriffHernandez1 1

Texas A&M University, College Station, TX

P-Fri-464 Development of Nanodelivery System for Sustained Release of Bioactive Anti-NogoA I. Yazdi1, N. Taghipour1, A. Munoz1, T. Boone1, and E. Tasciotti1 1

Houston Methodist Research Institute, Houston, TX

P-Fri-465 Biocompatibility Study of Drug Delivery Sutures in an Ovine Model for Cardiovascular Engineering Applications D. Lavin1, L. Zhang1, R. Quinn2, S. Hilbert2, A. Bert2, C. McFall2, J. Bustamante2, K. Merrigan2, S. Neighbors2, C. Thanos1, E. Mathiowitz1, and R. Hopkins2 1

Brown University, Providence, RI, 2The Children’s Mercy Hospital, Kansas City, MO

P-Fri-466 Combined Magnetic Nanoparticle-Based microRNA and Hyperthermia Therapy to Enhance the Treatment of Cancer P. Yin1, B. Shah1, and K-B. Lee1 Rutgers University, Piscataway, NJ

1

P-Fri-467 Bioresorbable Multi-Drug Delivery Conduit to Promote Peripheral Nerve Regeneration S. Ho1, K-M. Lin1, H. Sant1, J. Shea1, J. Agarwal1, and B. Gale1 University of Utah, Salt Lake City, UT

1

P-Fri-468 Drug Delivery via Magnetic Nanoparticles: Pioneering Treatment of Osteosarcoma T. Szasz1, A. Kovach1, S. Bulla1, J. Liao1, L. Williams1, C. Bulla1, and R. Prabhu1 Mississippi State University, Mississippi State, MS

University of Washington, Seattle, WA

Track: Drug Delivery, Biomaterials

Self Assembly and Nucleic Acid Drug Delivery Chairs: Rachael Sirianni, Bahareh Behkam P-Fri-410 Self-Assembling Drug Delivery Vehicles Direct Angiogenesis and Immune Signals V. Kumar1, B. Wang1, I-C. Li1, A. Jalan1, S. Shi1, and J. Hartgerink1 1

Poster Session

Rice University, Houston, TX

P-Fri-411 Layer-by-layer Self Assembly Through α Helical Polypeptides for Responsive Drug Delivery A. Gormley1, R. Chandrawati1, D. Aili2, and M. Stevens1 Imperial College London, London, United Kingdom, 2Linköping University, Linköping, Sweden

1

P-Fri-412 Morphologies of DNA Condensed with Functionalized Gold Nanoparticles E. Salgado1, G. Yesilbag2, V. Rotello2, R. Briber1, and J. Seog1 1

University of Maryland, College Park, MD, 2University of Massachusetts, Amherst, MA

P-Fri-413 Nanoengineered Amphiphilic Particles from Poly(glycerol sebacate)-coPoly(ethylene glycol) for Drug Delivery Applications P. Desai1, A. Venkataramanan1, J. Carrow1, M. Jaiswal1, A. Singh2, and A. Gaharwar1 1

Texas A&M University, College Station, TX, 2Cornell University, Ithaca, NY

P-Fri-414 Treatment Of Lysosomal Storage Disease With Therapeutic Polymersomes E. Pearce1, J. Larsen1, M. Byrne1, and D. Martin1 1

Auburn University, Auburn, AL

P-Fri-415 Lipid-polymeric Particles with a Patchy Surface C. Salvador-Morales1

1

P-Fri-469 Tunable Molecular Release With Micropatterned Nanoporous Gold Thin Films O. Kurtulus1, P. Daggumati2, and E. Seker2 Department of Chemical Engineering and Materials Science, University of California Davis, Davis, CA, 2Department of Electrical and Computer Engineering, University of California Davis, Davis, CA

1

1

1

George Mason University, Fairfax, VA

P-Fri-416 Incorporation and Simultaneous, Controlled Release Of Multiple, Diverse Comfort Molecules From A Single Daily Disposable Silicone Hydrogel Contact Lens C. White1, C. Bartel1, and M. Byrne1 1

Auburn University, Auburn, AL

See page 141 for Poster floor plan

BMES 2014

159

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-417 Optimizing Poly(beta-amino ester) Polyplexes for Enhanced Cellular Uptake and Particle Stability

P-Fri-428 Direct Tethering of Small Interfering RNA (siRNA) to Biodegradable Hydrogels for Its Controlled Delivery to Cells

J. Kim1, P. Mastorakos2, H. Park2, J. Suk2, J. Hanes2, and J. Green1

M. Nguyen1, A. Gilewski1, M. Levy2, and E. Alsberg1

1

School of Medicine, Johns Hopkins University, Baltimore, MD, 2Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD

1

P-Fri-418 Identifying Factors for Effective Control of DNA Nanoparticle Shape While Retaining In Vivo Efficacy

P-Fri-429 Real-time Visualization of PEI Polymer Dynamics During pH Buffering

J-M. Williford1, Y. Ren1, M. Archang1, and H-Q. Mao1

1

1

Johns Hopkins University, Baltimore, MD

P-Fri-419 Continuous-Flow Low-Voltage Microfluidic Electroporation for Gene Delivery N. Bhattacharjee1, L. Horowitz1, and A. Folch1 1

M. Gupta , S. Lee , S. Crowder , X. Wang , C. Nelson , C. Duvall , and H-J. Sung1 1

1

1

1

Vanderbilt University, Nashville, TN

B. Miryala1, Y. FENG1, A. Omer1, and K. Rege1 1

Fri

P. Mastorakos , A. da Silva , C. Zhang , J. Chisholm , S. Berry , W. Choi , H. Park1, M. Morales2, J. Hanes1, and J. Suk1 1

1

1

1

Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, 2Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

1

P-Fri-424 Dendritic Cell Subsets Interact with CpG-carrying Pathogen Mimicking Particles in a Phenotype Specific Manner J. Leleux1,2, P. Pradhan1, and K. Roy1,2 1

Georgia Institute of Technology, Atlanta, GA, 2Emory University, Atlanta, GA

P-Fri-425 Polyethyleneimine Coated Gold Nanoparticles For Efficient And Selective Gene Delivery B. Shrestha1 and L. Tang1 1

University of Texas at San Antonio, San Antonio, TX

P-Fri-426 Gold Nanoparticle Enhanced DNA and RNA Mediated Therapeutics S. Huang1, Y. Zu1, and S. Wang1 1

Louisiana Tech University, Ruston, LA

P-Fri-427 Targeted Intracellular Delivery of siRNA Via Polybasic Nanogels J. Pawlish1, L. Kouecheu1, M. Tabler1, J. Golodner1, B. Gonzales1, K. Paszek1, D. Singh1, C. Marcinkiewicz1, and O. Fisher1 1

Temple University, Philadelphia, PA

P-Fri-432 Modeling of Gel Flow and Drug Transport in the Vaginal Mucosa for Better Microbicide Gel Design Y. Gao1, A. Yuan1, and D. Katz1,2 Duke University, Durham, NC, 2Duke University Medical Center, Durham, NC

P-Fri-433 Development of Surface-Modified pH-Responsive Hydrogels for the Oral Delivery of Growth Hormone 1

P-Fri-423 Biodegradable DNA Nanoparticles for Efficient in vivo Gene Delivery 2

University of Maryland, College Park, MD

S. Steichen1, E. Fischer1, S. Yarborough1, C. O'Connor1, and N. Peppas1,2

Arizona State University, Tempe, AZ

1

1

1

P-Fri-422 Synthesis and Characterization of N- (2-hydroxy)-3-Chloride Derivatives of Aminoglycoside Polymer for Potential Application in Gene Delivery Poster Session

A. Goodfriend1, T. Welch1, K. Nguyen2, A. Nugent1, and J. Forbess1

E. Cesewski1, K. Higgins1, E. McMahon1, R. Brown1, J. Fix1, D. Freudenberger1, V. Niba1, H. Park1, G. Perdomo1, A. Seo1, A. Srivastava1, C. Tsui1, A. Whiteman1, and R. Zubajlo1

P-Fri-421 Reactive Oxygen Species-responsive Polyplex Micelles as a PEG-detachable Platform for Plasmid DNAdelivery 1

P-Fri-430 A Factorial Design For Therapeutic Agent Delivery For Pediatric Tracheomalacia

P-Fri-431 Fabrication of PLGA Microparticles for Improved HPV Vaccine Delivery

The University of Texas at Austin, Austin, TX

1

Howard University, Washington, DC, DC

University of Texas Southwestern Medical Center at Dallas, Dallas, TX, 2University of Texas Arlington, Arlington, TX

J. Knipe1, F. Chen1, and N. Peppas1

1

K. Curtis1, T. Abdus-Shakur1, and P. Chandran1

1

University of Washington, Seattle, WA

P-Fri-420 Enzymatically Degradable Microgels for the Oral Delivery of siRNA 1

Case Western Reserve University, Cleveland, OH, 2Albert Einstein College of Medicine, Bronx, NY

The University of Texas at Austin, Austin, TX, 2The University of Texas of Austin, Austin, TX

P-Fri-434 Adjuvant Conjugated Nano-particles for Vaccine Delivery: A Robust Method for Immune Response K. Brink1 1

Texas A&M University, College Station, TX

P-Fri-435 Alginate Based Hydrogels for Controlled-release of Zosteric Acid and Sodium Benzoate Q. Wang1 and B-M. Zhang Newby1 The University of Akron, Akron, OH

1

P-Fri-436 Poly(acrylic acid)-Poly(ethylene glycol) Microgels for Protein Delivery J. Rios1, G. Lu1, N. Seo1, T. Lambert1, and D. Putnam1 Cornell University, Ithaca, NY

1

P-Fri-437 Cell-Based Microarrays: A Platform to Facilitate Patient-Specific Therapy M. Carstens1, A. Acharya2, J. Lewis1, E. Huang3, and B. Keselowsky1 1 3

University of Florida, Gainesville, FL, 2University of California, Berkelely, Berkeley, CA, Cleveland Clinic, Cleveland, OH

P-Fri-438 Development of Continuous Flow Microspotter for High-Throughput Drug Screening and Cytotoxicity Evaluation J. Arellano1, J. Gammon1, J. Yang1, B. Gale1, and M. Janat-Amsbury1 1

University of Utah, Salt Lake City, UT

P-Fri-439 Microglia Migration and Interactions with Dendrimer in Brain in the Presence of Neuroinflammation F. Zhang1,2, E. Nance1, Y. Alnasser1, R. Kannan1, and S. Kannan1 Johns Hopkins University School of Medicine, Baltimore, MD, 2Johns Hopkins University, Baltimore, MD

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

160

BMES 2014

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-440 moved to P-Th-359

P-Fri-661 An Automated, Pump-less Microfluidic Device for Image-Cytometry Measurements of Oral Lesions T. Abram1 and J. McDevitt1

Track: Nano to Micro Technologies, Device Technologies and Biomedical Robotics

1

Nanotechnology, Microfluidic Platforms, Theranostics Chairs: Maribel Vazquez, Jeff Zahn

A. Chen , M. Jackson , Y. Hu , A. Lin , J. Young , R. Langsner , and R. Drezek 1

1

1

University of Washington, Seattle, WA

1

University of Washington, Seattle, WA

P-Fri-664 3D Printed Microfluidic Oxygen Mixer

P-Fri-652 Spectral Shifting of Bare and PEGylated Plasmonic Nanoparticles in Biological Environments 2

1

1

University of Tennessee, knoxville, TN

1

N. Taparia1, R. Aaron1, S. Tavakoli1, A. Karchin1, and N. Sniadecki1

A. Au1 and A. Folch1

K. Mamun1, F. Tulip1, N. McFarlane1, and S. Islam1

1

P-Fri-662 Reusable Polyurethane Negative Mold for Micropost Fabrication

P-Fri-663 3D-Printed Microvalves and Micropumps

P-Fri-651 Vertically Aligned Carbon Nanofiber Biosensor Platform 1

Rice University, Houston, TX

G. Mauleon1, L. Villafana1, and D. Eddington1 1

1

Rice University, Houston, TX, 2Salk Institute for Biological Studies, La Jolla, CA

University of Illinois at Chicago, Chicago, IL

P-Fri-665 3D Printed Microfluidic Devices for Oxygen Control in Cell Culture

P-Fri-653 Interaction of Flagellin with Single-walled Carbon Nanotubes

M. Brennan1 and D. Eddington1

I. Macwan , Z. Zhao , O. Sobh , and P. Patra

P-Fri-666 Numerical And Experimental Investigation Of Sharp-edge-based Acoustofluidic Mixers

1

1

1

2

1

University of Bridgeport, Bridgeport, CT, 2University of Pennsylvania, Philadelphia, PA

P-Fri-654 Nanoparticle Surface Charge Impacts Vesicle Motion in Cortical Neurons C. Godzich , D. Di Carlo , and A. Kunze 1

1

1

1

University of California Los Angeles, Los Angeles, CA

P-Fri-655 Digital Microfluidic Platform for Cell Spheroid-Based Migration/Invasion Assays B. Bender , A. Aijian , and R. Garrell 1

1

1

1

University of California, Los Angeles, Los Angeles, CA

P-Fri-656 Preparation of a Nano-patterned Polymer Replica for Reducing Catheter Associated Inflammation and Infection L. Liu1, B. Ercan1, S. Ni2, L. Sun1, and T. Webster1

1

University of Illinois at Chicago, Chicago, IL

N. Nama1, P-H. Huang1, T. Jun Huang1, and F. Costanzo1 1

The Pennsylvania State University, University Park, State College, PA

P-Fri-667 Fast and Effective Mixing of High Viscosity Liquids via Acoustofluidic Bubble Cavitations A. Ozcelik1, Y. Xie1, A. Nawaz1, and T. Huang1 1

Poster Session

The Pennsylvania State University, University Park, PA

P-Fri-668 Controllable Generation of Chemical Gradient via Acoustically Oscillated Sharp Edges P-H. Huang1, C. Chan1, N. Nama1, Y. Chen1, Y. Xie1, and T. Huang1 1

The Pennsylvania State University, University Park, PA

1

Northeastern University, Boston, MA, 2Donghua University, Shanghai, China, People's Republic of

P-Fri-669 Droplet Generation and Trapping for High-throughput Bioassays

P-Fri-657 Macrophage Phenotypic Response to Silica Nanotparticles

D. Hu1, Z. Zhao1, G. Ghosh1, and J. Lo1

H. Herd1,2, K. Bartlett1,2, J. Gustafson1,2, and H. Ghandehari1,2

P-Fri-670 A Programmable Acoustofluidic Pump

1

University of Utah, Salt Lake City, UT, 2Utah Center for Nanomedicine, Salt Lake City, UT

1

University of Michigan-Dearborn, Dearborn, MI

P-Fri-658 Highly Controlled Janus Nanoparticle Synthesis for Cancer Therapy

P-H. Huang1, N. Nama1, Z. Mao1, Y. Chen1, Y. Xie1, and T. Huang1

E. Campbell1, J. Tang1, Y. Xia1, and T. Sulchek1

P-Fri-671 Single Cell Capturing and Long-Term Culture Using a Microfluidic DualWell Device

1

Georgia Institute of Technology, Atlanta, GA

P-Fri-659 Controlled Gold Nanorod Assembly with Well-defined Surface Plasmon Pattern on Substrates Z. Mei1 and L. Tang1 1

University of Texas at San Antonio, San Antonio, TX

P-Fri-660 Cell-Free Protein Synthesis in Miniaturized Devices and their Effects on the Synthesis Yield K. Jackson1 and Z. Fan1 1

1

The Pennsylvania State University, University Park, PA

C-H. Lin1,2, Y-H. Hsiao1,3, H-C. Chang1,2, C-K. He1,2, I-M. Chiu1,2, and C-H. Hsu1,2,3 National Health Research Institute, Miaoli County, Taiwan, 2National Chung Hsing University, Taichung, Taiwan, 3National Tsing Hua University, Hsinchu, Taiwan

1

P-Fri-672 Compact, Low-power Micropump via Electrolysis and Catalytic Recombination towards Integrated Microfluidic Systems A. Michaelian1, C. Truong1, and U. Kim1 Santa Clara University, Santa Clara, CA

1

University of Florida, Gainesville, FL

See page 141 for Poster floor plan

BMES 2014

161

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-673 High-throughput Enrichment of Particles from mm/s Fluid Flow Based on AC Electrokinetics

P-Fri-684 Fabrication and Investigation of a Miniaturized Nanochannel Drug Delivery System

Q. Yuan1, C. Cheng1, H. Cui1, and J. Wu1

R. Hood1, S. Ferrati1, and A. Grattoni1

1

The University of Tennessee-Knoxville, Knoxville, TN

P-Fri-685 A Self-Contained Multi-Step Immunoassay for Point-of-Care Applications

C. Lu1, S. Ma1, D. Loufakis1, Z. Cao1, Y. Chang1, and L. Achenie1

I. Nanayakkara1, J. Karimi1, and A. Lee1

Virginia Tech, Blacksburg, VA

1

University of California, Irvine, Irvine, CA

P-Fri-675 Microfluidic Generation of Cell-Like Liposomes

P-Fri-686 Multiplexed Electronic Protein Analysis: A Comprehensive Design Space

D. Vallejo1 and A. Lee1

S. Emaminejad1, R. Dutton1, R. Davis1, and M. Javanmard1

1

University of California, Irvine, Irvine, CA

1

Stanford University, Stanford, CA

P-Fri-676 Mathematical Simulations of Heat Transfer and Fluid Dynamics in a Microfluidic Calorimeter with Integrated Thin-film Thermopiles

P-Fri-687 Micro and Millifluidic Platforms for Scalable Production of Multifunctional Nanoparticles

G. Nestorova1, N. Crews 1, and E. Guilbeau1

S. Kim1, M. Toth1, G. Bao1, D. Giddens1, and Y. Kim1

1

Louisiana Tech University, Ruston, LA

1

Georgia Institute of Technology, Atlanta, GA

P-Fri-677 Microfluidic Generation of Stiffness-tunable Polyacryamide Substrate for Studying Mechanical Regulation of Cell Culture Substrate on Cancer Cells

P-Fri-688 Facile Construction of Magnetic Enzyme Nanosystem as a Dual-platform for Fapid Tryptic Digestion

H. Yi-Hsing1,2, C. Chihchen2, and H. Chia-Hsien1,3

G. Cheng1 and S-Y. Zheng1

National Health Research Institutes, Miaoli County, Taiwan, 2National Tsing Hua University, Hsinchu, Taiwan, 3National Tsing Hua University, Hsin chu, Taiwan

1

1

P-Fri-678 Immobilization of Oxalyldihydrazide on Poly(Dimethylsiloxane) S. Stone1 and B. Hollins1 1

Fri

The Houston Methodist Research Institute, Houston, TX

P-Fri-674 Diffusion-based Microfluidic PCR for "One-pot" Analysis of Cells 1

Poster Session

1

Louisiana Tech University, Ruston, LA

P-Fri-679 A Portable Microfluidic Capillary Electrophoresis Platform for Detecting Organochloride Contaminants in Drinking Water J. Lee1, E. Jensen2, H. Mehrabani2, H. Jiao2, and J. Kim1 1

Texas Tech University, Lubbock, TX, 2HJ Science & Technology, Inc., Berkeley, CA

P-Fri-680 Integrating 2D and 3D Microelectrodes in Plastic Microfluidic Devices Allowing Spatial and Temporal Control of Electric Fields for Detection or Stimulation. J. Paredes1,2, K. Fink3,4, M. Chooljian3,4, and D. Liepmann3,4,5 CEIT and Tecnun (University of Navarra), Donostia-San Sebastián, Spain, 2CIC microGUNE, Arrasate-Mondragon, Spain, 3University of California, Berkeley, Berkeley, CA, 4UC Berkeley – UC San Francisco Graduate Program in Bioengineering, Berkeley, CA, 5Berkeley Sensors and Actuators Center, Berkeley, CA

Penn State University, State College, PA

P-Fri-690 Bioelectrical Impedance Measurements to Detect Changes in Tight Junction Expression at Cell Junctions R. Kraya1 and P. Searson1,2 1

Institute for Nanobiotechnology, Baltimore, MD, 2Johns Hopkins University, Baltimore, MD

P-Fri-691 Selective Detection and Quantification of Modified DNA With Solid-State Nanopores O. Zahid1, A. Carlsen1, J. Ruzicka2, E. Taylor2, and A. Hall1 Wake Forest University School of Medicine, Winston-Salem, NC, 2University of North Carolina Greensboro, Greensboro, NC

1

)

P-Fri-692 Label Free, Multiplexed Plasmonic Gold Nanorod Biochip Y. wang1 and L. Tang1 1

University of Texas at San Antonio, San Antonio, TX

1

P-Fri-681 Trapping of Submicron Beads using 3D Embedded-electrode Insulator-based Dielectrophoresis (3D-ETT DEP) D. Nakidde1 and M. Agah1 1

Virginia Tech, Blacksburg, VA

P-Fri-682 Microfluidic Viscoelastic Hemostatic Assay for Coagulation Diagnostics R. Judith1, J. Fisher2, R. Spero2, B. Oberhardt1,3, M. Falvo1, R. Taylor1, and R. Superfine1 1 3

University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Rheomics Inc., Chapel Hill, NC, North Carolina State University, Raleigh, NC

P-Fri-683 Single Cell Mechanophenotyping and Mechanotransduction using a Microfluidic Micropipette Array

L. Lee1, V. Murray1, J. Heureaux1, and A. Liu1 1 University of Michigan, Ann Arbor, MI

P-Fri-693 Microfluidic Organ-on-a-Chip: Bi-directional Fluidic Flow Enhances Multicell-type, Three-dimensional Human Primary Liver Cell Culture M. Esch1, J-M. Prot1, P. Miller1, D. Applegate2, and M. Shuler1 1

Cornell University, Ithaca, NY, 2RegeneMed, San Diego, CA

P-Fri-694 Treatment of Vascular Calcification with Elastin-Targeted Theranostic Nanoparticles K. Bennett1 and C. Simpson1 1

Mississippi State University, Mississippi State, MS

P-Fri-695 Evaluating Antibody Conjugated Magnetic Microspheres for the Depletion of Interleukin-1 Beta for Osteoarthritis Treatment A. Monsalve1, B. Kozissnik1, A. Garraud1, E. Yarmola1, K. Allen1, and J. Dobson1 1

University of Florida, Gainesville, FL

P-Fri-696 Molecular Targeting and Imaging Using Virus-Based Nanoparticle-Antibody Conjugates J. Whitney1, M. McBurney1, D. Thompson2, P. Dawson2, and N. Steinmetz1 Case Western Reserve University, Cleveland, OH, 2The Scripps Research Institute, La Jolla, CA

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

162

BMES 2014

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-697 Clinically Relevant Carbon Nanotube Dispersions for Microwave Hyperthermia

P-Fri-305 Directed Chemotaxis Of Retinal Progenitor Cells In 3D Hydrogels For Rational Cell Delivery Vehicles

S. Xie1, F. Gao2, S. Patel1, J. Booske2, S. Hagness2, and B. Sitharaman1

A. Koppes1,2,3, M. Oudin3, P. Baranov2, M. Miller3, F. Gertler3, M. Young2, D. Lauffenburger3, and R. Carrier1

1

Stony Brook University, Stony Brook, NY, 2University of Wisconsin-Madison, Madison, WI

Northeastern University, Boston, MA, 2Schepens Eye Research Institute & Harvard Medical School, Boston, MA, 3Massachusetts Institute of Technology, Cambridge, MA

1

P-Fri-698 Bioengineering Silicon Quantum dot Theranostics using a Network analysis of Metabolomic and Proteomic Data in Cardiac Ischeamia F. Erogbogbo1 and P. Gladding2 San Jose State University (SJSU), San Jose, CA, 2North Shore Hospital, Auckland, New Zealand

1

P-Fri-699 Dendritic Wedge-Based Display of Polyarginine Peptides on Semiconductor Quantum Dots Mediates Differential Cellular Binding and Internalization J. Breger1,2, K. Susumu1, M. Muttenhaler3, J. Delehanty1, P. Dawson3, and I. Medintz1 U.S. Naval Research Laboratory, Washington, DC, 2American Society for Engineering Education, Washington, DC, 3The Scripps Research Institute, La Jolla, CA

1

)

P-Fri-700 Pump-Free Membrane-Controlled Perfusion Microfluidic Platform V. Goral1, E. Tran1, and P. Yuen1 1

Corning Incorporated, Corning, NY

J. Zuidema1, M. Hyzinski-Garcia2, K. Van Vlasselaer1, N. Zaccor1, G. Plopper1, A. Mongin2, and R. Gilbert1 1

Rensselaer Polytechnic Institute, Troy, NY, 2Albany Medical College, Albany, NY

P-Fri-307 Increased Neurogenesis in Close Proximity to Flow-Stimulated Endothelial Cells C. Dumont1, G. Dai1, and D. Thompson1 1

Rensselaer Polytechnic Institute, Troy, NY

P-Fri-308 Enhanced Myelination by Focal Electrical Stimulation in Microfluidic Platform H. Lee1, I. Yang1,2, and N. Thakor1,2

P-Fri-701 Design of a Custom Multiwell Platform for the Simple and Rapid Preparation of Polyacrylamide Stiffness Assay N. Ahmed1, H. Stevenson1, A. Karadaghy1, and S. Zustiak1 1

)

P-Fri-306 Enhanced Astrocyte GLT-1 Mediated Glutamate Uptake and Migration Induced by Fibronectin-coated Poly-L-lactic Acid Fibers

Saint Louis University, St Louis, MO

National University of Singapore, Singapore, Singapore, 2Johns Hopkins University, School of Medicine, Baltimore, MD

1

P-Fri-309 3D Printing of Nanostructured Nerve Guidance Scaffolds with Graphene Nanoplatelets C. O'Brien1 and L. Zhang1 1

Track: Neural Engineering, Device Technologies and Biomedical Robotics

Neural Engineering II: Glia, PNS Interfaces, and CNS Injury Chairs: Teresa Murray, Jennifer Kang-Mieler P-Fri-301 Static Stretch Affects Neural Stem Cell Differentiation Along the Oligodendrocyte Lineage J. Arulmoli1, M. Pathak1, L. McDonnell1, and L. Flanagan1 1

University of California, Irvine, Irvine, CA

P-Fri-302 Application of Optical Clearing Methods to Tissue-Engineered Neural Microtissues M. Boutin1 and D. Hoffman-Kim1 1

Brown University, Providence, RI

P-Fri-303 Spinal Cord Injury Treatments Tested In Vivo Integrating Neural Stem Cell Delivery and Lineage Specification via Immobilized Growth Factors H. Li1, T. Ham1, A. Wilkinson1, A. Koenig1, and N. Leipzig1 1

The George Washington University, Washington, DC

P-Fri-310 Astrocyte Aligning Using Laminin Micropattern on Cell Adhesive Substrate S. Joo1, J. Kim2, E. Lee2, N. Hong1, W. Sun2, and Y. Nam1 KAIST, Daejeon, Korea, Republic of, Brain Korea , Korea University College of Medicine, Seoul, Korea, Republic of 1

2

21

P-Fri-311 Short Term Electrical Stimulation to Promote Nerve Repair and Functional Recovery of Sciatic Nerve Injuries W. Zhou1, C. Calvey2, K. Sloan-Stakleff2, P. Sendelbach-Sloan2, W. Lanzinger2, and R. Willits1 1

University of Akorn, Akron, OH, 2Akron General Medical Center, Akron, OH

P-Fri-312 A Multi-Branch Nerve Scaffold With Embedded Microwires In Neural Interfacing Applications B. Kim1, E. Ibarra1, B. Garza1, R. Luna1, and Y. Choi1 1

University of Texas – Pan American, Edinburg, TX

P-Fri-313 Electrical Stimulation of Single Somatic Nerve Fascicles are Sufficient to Reduce Hypertension A. Kanneganti1, S. Fatemi1, C. Nothnagle 2, M. Wijesundara 2, M. Mizuno3, S. Smith3, Y-T. Kim1, and M. Romero-ortega1 Univ. Of Texas at Arlington, Arlington, TX, 2Univ. Of Texas at Arlington Research Institute, Fort Worth, TX, 3Univ.of Texas Southwestern Medical Center, Dallas, TX

1

University of Akron, Akron, OH

P-Fri-304 Effects of Shear and Electric Stimulation on the Migrating Behavior of Microglia

P-Fri-314 Neurophysiologic Evaluations of Nano Graphene Multi-Electrode Array for Neural Interfaces

S. Ahn1, S. Song1, E. Park1, M. Son1, J-S. Park1, and J. Shin1

C. Chen1, W. Yi1, Z. Feng1, C. Zhou1, J. Cavanaugh1, and M. Cheng1

1

KAIST, Daejeon, Korea, Republic of

1

Wayne State University, Detroit, MI

P-Fri-315 Thin Film Wireless Electrodes Used To Deliver Therapeutic Stimulation P. Gamble1, M. Stephen1, M. MacEwan1, and W. Ray1 1

Washington University in St Louis, St Louis, MO

See page 141 for Poster floor plan

BMES 2014

163

Poster Session

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-316 The Role of Oxidative Stress in Axonal Pathology R. Dastgheyb1, G. Gallo2, and K. Barbee1 1

Drexel University, Philadelphia, PA, 2Temple University, Philadelphia, PA

P-Fri-317 Local Delivery of Paclitaxel from Aligned Electrospun Poly(lactic-acid) Microfibers Promotes Neurite Extension In Vitro J. Roman1, A. Hurtado1, and H-Q. Mao1 1

Johns Hopkins University, Baltimore, MD

P-Fri-318 Directing NPC Differentiation with Natural Biomaterials: Implications for Spinal Cord Repair

)

P-Fri-327 Wide Field-of-view, Dual-region Multiphoton Imaging Across Extended Cortical Networks J. Stirman1,2, I. Smith1, M. Kudenov3, and S. Smith1,2,4 Neuroscience Center, University of North Carolina, Chapel Hill, NC, 2Carolina Institute for Developmental Disabilities, Chapel Hill, NC, 3Department of Electrical and Computer Engineering, North Carolina State University, Raleigh, NC, 4Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC 1

P-Fri-328 Carbon Nanotube/Polyethylene Glycol Hydrogel Composite as an in vitro Model for Neural Tissue Engineering K. Shah1, D. Vasileva1, and S. Zustiak1 1

S. Geissler1, A. Sabin2, O. Gooden2, R. Besser2, and C. Schmidt2 1

The University of Texas, Gainesville, FL, University of Florida, Gainesville, FL

P-Fri-319 Compromised Axonal Functionality After Neurodegeneration and/or Traumatic Brain Injury. P. Maia1 and N. Kutz1 1

University of Washington, Seattle, WA

P-Fri-320 Transcriptomics and Metabolomics of Surgically-induced Cervical Syringomyelia A. Wilkinson1, M. Farrag1, S. Haft2, P. Joshi1, H. Huang1, L. Shriver1, and N. Leipzig1 1

University of Akron, Akron, OH, 2Claremont McKenna College, Claremont, CA

P-Fri-321 Delivery of Paramagnetic Nanoparticles after Traumatic Brain Injury in Mice V. Bharadwaj1, K. Rumbo1, V. Kodibagkar1, and S. Stabenfeldt1 1

Poster Session

Fri

Arizona State University, Tempe, AZ

P-Fri-322 Semi-Interpenetrating Alginate/Laminin Hydrogels to Study Mechanism for Neural Remodeling Following Traumatic Brain Injury N. Sturdivant1, A. Haileyesus1, J. Carradini1, and K. Balachandran1 1

University of Arkansas, Fayetteville, AR

P-Fri-323 Pairing Vagus Nerve Stimulation With Rehabilitative Training Enhances Functional Recovery After Traumatic Brain Injury D. Pruitt1,2, A. Schmid1,2, C. Choua1,2, L. Kim1,2, C. Abe1,2, J. Trieu1,2, M. Kilgard1,2, and R. Rennaker1,2 The University of Texas at Dallas, Richardson, TX, 2Texas Biomedical Device Center, Richardson, TX

1

P-Fri-324 Incidence and Risk of Concussive Injury in Vehicle Crashes H. Gabler1 1

Virginia Tech, Blacksburg, VA

P-Fri-325 Stretch Induced Effects on Callosal Pathway Flavoprotein Autofluoresence A. Fan1, K. Stebbings1, D. Llano1, and T. Saif1 1

University of Illinois at Urbana-Champaign, Urbana, IL

P-Fri-326 Traumatic Brain Injury Resulted in Increased Aquaporin-4 Expression Relevance to Post-Injury Edema? N. Sturdivant1, A. Haileyesus1, J. Carradini1, and K. Balachandran1 1

Saint Louis University, St Louis, MO

2

University of Arkansas, Fayetteville, AR

Track: Orthopaedic and Rehabilitation Engineering, Biomechanics

Articular Cartilage and Joints Chairs: Spencer Lake, Meng Deng P-Fri-545 In-Vitro Modeling of Osteoarthritis with a Silk Scaffold and Mechanical Compression S. Berry1, L. Hayward1, and D. Kaplan1 1

Tufts University, Medford, MA

P-Fri-546 Testing Efficacy of Pain Management Therapies in a Rodent Model of PostTraumatic Knee Osteoarthritis H. Kloefkorn1, B. Jacobs1, and K. Allen1 1

University of Florida, Gainesville, FL

P-Fri-547 Enhanced Stem Cell Functions on Cold Atmospheric Plasma Treated Nanocomposite Cartilage Scaffolds W. Zhu1, M. Keidar1, and L. Zhang1 1

The George Washington University, Washington, DC

P-Fri-548 Designing a Probe for the Magnetic Collection of Molecular Biomarkers in Joints for Early Detection of Osteoarthritis Y. Shah1, C. Velez Cuervo1, E. Yarmola1, D. Arnold1, J. Dobson1, and K. Allen1 1

University of Florida, Gainesville, FL

P-Fri-549 Improve the Efficiency of Articular Cartilage Indentation Test by Principal Component Analysis X. Chen1, B. Zimmerman1, and X. Lu1 1

University of Delaware, Newark, DE

P-Fri-550 Low Intensity Vibration Enhances Cartilage Thickness in Young Obese Mice without Compromising Bone. V. Bhandal1, T. Pamon1, M. Chan1, and C. Rubin1 1

Stony Brook University, Stony Brook, NY

P-Fri-551 Wear in Total Knee Replacements with Oxidized Zirconium Femoral Components Explanted Postmortem M. Bland1, K. Austriaco1, A. Eberhardt1, and J. Lemons1 1

University of Alabama at Birmingham, Birmingham, AL

P-Fri-552 Degradation-dependent Alterations in Articular Cartilage Lubricating Mechanisms E. Bonnevie1, D. Galesso2, C. Secchieri2, and L. Bonassar1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

164

BMES 2014

Cornell University, Ithaca, NY, 2Fidia Farmaceutici, Padua, Italy

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-553 Calcium Phosphate Clay Nanoparticle Bone Cements with Enhanced Mechanical Properties

P-Fri-539 Biasing MSC Differentiation into an Osteoblastogenic Fate Using LIV Leads to Higher Bone Count and Quality

U. Jammalamadaka1, K. Tappa2, S. Karnik1, and D. Mills1

T. Samphel1, D. Frechette2, E. Chan2, and C. Rubin2

1

Louisiana Tech University, Ruston, LA, 2Louisiana Tech University, Ruston, Afghanistan

1

Stony Brook University, woodside, NY, 2Stony Brook University, Stony Brook, NY

P-Fri-554 The Effect of Delayed Mechanical Stimulation in an in vitro Microfracture Model

P-Fri-540 Electrical and Dielectric Properties of Bone and Its Constituents with Frequency

M. Park1, M. Chatterjee1, B. Zimmerman1, L. Snyder-Mackler1, and X. Lu1

H. Ranu1 and D. Rai2

1

University of Delaware, Newark, DE

P-Fri-555 Alterations of Articular Cartilage Surfaces after Mechanical Insult E. Bonnevie1, M. Delco1, P. Alexander2, R. Tuan2, L. Fortier1, and L. Bonassar1 1

Cornell University, Ithaca, NY, 2University of Pittsburgh, Pittsburgh, PA

)

T. Mwangi1, R. Bowles1, D. Tainter2, R. Bell2, D. Kaplan3, and L. Setton1,2 Duke University, Durham, NC, Duke University Medical Center, Durham, NC, Tufts University, Medford, MA 2

P-Fri-541 Intracranial Analysis of Non-Sutural Osteoblast Mechanobiology in the Developing Mammal Skull H. Weiss-Bilka1, S-Y. Liu2, and M. Ravosa1

P-Fri-556 In Vivo Characterization of Silk Fibroin Microparticles for Intra-Articular Drug Delivery 1

American Orthopaedic Biomechanics Research Institute, Atlanta, GA, 2Shobit University, Meerut, India

1

3

University of Notre Dame, Notre Dame, IN, 2Indiana University School of Dentistry, Indianapolis, IN

1

P-Fri-542 Morphological Analysis of Changes in the Thoracic Skeleton with Sex and Age A. Weaver1, S. Schoell1, C. Nguyen2, and J. Stitzel1 Wake Forest University Center for Injury Biomechanics, Winston-Salem, NC, 2Wake Forest University, Winston-Salem, NC

1

Track: Orthopaedic and Rehabilitation Engineering

S. Leslie1, D. Cohen1, J. Sedlaczek 2, E. Pinsker3, Z. Schwartz1, and B. Boyan1

Bone

Virginia Commonwealth University, Richmond, VA, 2Otto-von-Guericke University, Magdeburg, Germany, 3Georgia Institute of Technology, Atlanta, GA

1

Chairs: John Cotton, Joel Bumgardner

P-Fri-544 Fracture Healing in a Mouse Model of Saether-Chotzen Syndrome

P-Fri-533 Experimental Investigation of Bone Drilling Performance

S. Hyzy1, G. Reddy1, R. Olivares-Navarrete1, Z. Schwartz1,2,3, and B. Boyan1,2

E. MacDonald1, S. Russel1, and S. Schmid1 1

Virginia Commonwealth University, Richmond, VA, 2Georgia Institute of Technology, Atlanta, GA, 3University of Texas Health Science Center at San Antonio, San Antonio, TX

1

University of Notre Dame, Notre Dame, IN

P-Fri-534 Cellulose-based Scaffolds for Enhanced Bone Formation by Human Adipose-derived Stem Cells H-J. Park1, K. Yang1, A-N. Cho1, S. Yu2, S. Im2, and S-W. Cho1 Department of Biotechnology, Yonsei University, Seoul, Korea, Republic of, 2Department of Chemical and Biomolecular Engineering, KAIST, Daejeon, Korea, Republic of

1

P-Fri-535 Anti-Infective Calcium Phosphate Bone Cement Louisiana Tech University, Ruston, Afghanistan, 2Louisiana Tech University, Ruston, LA

1

P-Fri-536 In-Vivo Biocompatibility and Toxicity of Single Walled Carbon Nanotube Composites for Bone Tissue Engineering A. Gupta1, T. Liberati1, S. Verhulst1, B. Main1,2, M. Roberts1, A. Potty1, and S. El-Amin1,3 Southern Illinois University School of Medicine, Springfield, IL, 2University of Illinois at Springfield, Springfield, IL, 3Southern Illinois University, School of Medicine, Springfield, IL

1

P-Fri-537 Biomechanical Investigation of Extracorporeal Irradiation Therapy in Malignant Bone Tumours S. Chauhan1, K. Manoj2, S. Rastogi2, S. Khan2, and A. Prasad1 Indian Institute of Technology Delhi, New Delhi, India, 2All India Institute of Medical Sciences, New Delhi, India, New Delhi, India

1

P-Fri-538 Mitigating Effect Of Dynamic Hydraulic Flow Stimulation On Bone Loss In Functional Disuse Model T. Chu1, M. Hu1, and Y-X. Qin1 Stony Brook University, Stony Brook, NY

Track: Respiratory Bioengineering, Biomechanics

Computational Modeling of the Respiratory System Chairs: Donald Gaver

K. Tappa1, U. Jammalamadaka2, S. Karnik2, and D. Mills2

1

P-Fri-543 A Controlled Delivery Method to Localize Stem Cells

P-Fri-522 Computational Modeling of the Alveolar-Scale Deformation during Pulmonary Fibrosis L. Caggiano1, M. Schickel1, and S. Ghadiali1 The Ohio State University, Columbus, OH

1

P-Fri-524 Investigation Into the Enhancement of Surfactant Transport and Sorption in a Model of Airway Reopening J. Pillert1, H. Fujioka1, D. Halpern2, and D. Gaver1 Tulane University, New Orleans, LA, 2University of Alabama, Tuscaloosa, AL

1

P-Fri-525 A Computational Model of Epithelial Cell Monolayer Disruption in the Lung B. Ma1 and J. Bates1 University of Vermont, Burlington, VT

1

P-Fri-526 Mechanistic Computational Model of Lung Tissue Bioenergetics and the Effect of Acute Lung Injury X. Zhang1, R. Dash2, A. Clough1, E. Jacobs3, and S. Audi1 Marquette University, Milwaukee, WI, 2Medical College of Wisconsin, Milwaukee, WI, Zablocki VA Medical Center, Milwaukee, WI

1 3

See page 141 for Poster floor plan

BMES 2014

165

Poster Session

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-527 Computational Simulation of Eustachian Tube Sonotubometry Test J. Torres-Rodriguez1 and S. Ghadiali1 1

The Ohio State University, Columbus, OH

P-Fri-528 A Scaling Model of the Lung Parenchyma in Aging B. Suki1 1

Boston University, Boston, MA

P-Fri-529 Agent-Based Models For Studying Stem Cell Dynamics On Decellularized Lung Scaffolds J. Pothen1, V. Rajendran2, D. Wagner1, D. Weiss1, and J. Bates1 University of Vermont College of Medicine, Burlington, VT, 2Essex High School, Essex Junction, VT

1

P-Fri-530 Real-Time Numerical Simulation of Ozone Transport and Uptake in an Anatomically-Accurate Model of the Respiratory Tract S. Motevalian1, J. Ultman1, and A. Borhan1 1

The Pennsylvania State University, University Park, PA

P-Fri-531 Numerical Simulation of Airflow in a CT-based Human Airway Model With Physiologically Appropriate Boundary Conditions R. Gruetzemacher1,2, A. Arabshahi1,2, and K. Sreenivas1,2 The University of Tennessee, Chattanooga, Chattanooga, TN, 2SimCenter: National Center for Computational Engineering, Chattanooga, TN

1

P-Fri-505 Intramuscular Sarcomere Length Variability in Ageing Healthy Mouse Diaphragm Muscle K. Martin1, C. Henry1, S. Peirce-Cottler1, and S. Blemker1 1

University of Virginia, Charlottesville, VA

P-Fri-506 Modeling the Mucociliary Clearance in Bronchial Bifurcations M. Manolidis1, B. Louis2, D. Isabey2, J. Grotberg2,3, and M. Filoche1,2 Ecole Polytechnique, Palaiseau, France, 2INSERM, Créteil, France, 3University of Michigan, Ann Arbor, MI

1

P-Fri-507 Spatial Organization of Constriction Pattern Contributes to Apparent Airway Hyperresponsiveness And Intersubject Variability in Response to Challenge and Dilation S. Amin1 and B. Suki2 1

Boston University, Boston, MA, 2Boston University, BOSTON, MA

P-Fri-508 Mechanical Properties and Gelation Kinetics of Lung ECM Hydrogels Tailored for Regenerative Medicine R. Pouliot1, R. Takahashi1, M. Malik1, and R. Heise1 1

Virginia Commonwealth University, Richmond, VA

P-Fri-509 Small Charged Compound Lowers Surface Tension In Alveoli Flooded With Albumin Solution A. Kharge1 and C. Perlman1 Stevens Institute of Technology, Hoboken, NJ

1

P-Fri-532 Dynamic Multi-scale Model of the Lung J. Ryans1, H. Fujioka1, D. Halpern2, and D. Gaver III1 1

Tulane University, New Orleans, LA, 2University of Alabama, Tuscaloosa, AL

P-Fri-510 A Composite Cost Function for Quantifying Ventilator-induced Lung Injury J. Bates1 and B. Smith1 1

Poster Session

Fri

Track: Respiratory Bioengineering, Biomechanics

Respiratory Transport and Mechanics I Chairs: Jason Bates

)

P-Fri-501 Mechanics of the Pulmonary Airway System in Healthy Subjects and Patients during Forced Expiration Maneuver A. Pradel1, K. Blanc1, P. Gilfriche2, T. Similowski1, C. Straus1, and M. Filoche3,4 1 3

Université Pierre et Marie Curie, Paris, France, 2Ecole des Mines-ParisTech, Paris, France, Ecole Polytechnique, Palaiseau, France, 4INSERM, Créteil, France

)

P-Fri-502 Adhesive Properties of Ultra-Low Volume Mucus Samples during Otitis Media N. Higuita-Castro1, J. Malik1, J. Swarts2, and S. Ghadiali1 1

Z. Chen1,2, Y. Wang1, X. Jia1, and M. Zhang1 1

Respiratory Transport and Mechanics II Chairs: Bela Suki P-Fri-511 Effect of Airway Size on Magnitude of Bronchodilatory and Bronchoprotective Responses to Breathing B. Harvey1, H. Peterson1, H. Parameswaran1, A. Zollinger1, and K. Lutchen1 1

B. Henry1, Z. Dai1, and T. Royston1 University of Illinois at Chicago, Chicago, IL

Boston University, Boston, MA

P-Fri-512 Plasma Proteins Required For Exogenous Surfactant To Lessen Ventilation Injury Y. Wu1 and C. Perlman1 1

Stevens Institute of Technology, Hoboken, NJ

P-Fri-513 Visualization of Dynamic Pulmonary Surfactant Transport during Simulated Airway Reopening E. Yamaguchi1, M. Dearden1, L. Nolan1, and D. Gaver1 1

The Ohio State University, Columbus, OH, 2The University of Tennessee, Knoxville, TN

P-Fri-504 Modeling Lung Morphometry Using a Hybrid Power Law Method 1

Track: Respiratory Bioengineering, Biomechanics

The Ohio State University, Columbus, OH, 2University of Pittsburgh, Pittsburgh, PA

P-Fri-503 Effect of Long-term Alcohol Exposure on Mucociliary Clearance through 3D High Speed Imagingand Dynamic Modeling

University of Vermont, Burlington, VT

Tulane University, New Orleans, LA

P-Fri-514 Neulizable Decellularized Lung Matrix Solution for Hyperoxia-induced Acute Lung Injury J. Wu1, Q. Ding1, A. Dutta1, R. Iyer2, P. Ravikumar2, L. Wu2, C. Hsia2, and Y. Hong1 University of Texas at Arlington, Arlington, TX, 2University of Texas Southwestern Medical Center, Dallas, TX

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

166

BMES 2014

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-515 Distribution of Advective Ventilation in a Three-Dimensional Canine Lung Model

P-Fri-233 Mesenchymal Stromal Cell Influence on Pulmonary Metastasis After Removal of Primary Osteosarcoma

J. Herrmann1, M. Tawhai2, and D. Kaczka3

M. Aanstoos1, D. Regan1, R. Rose1, L. Chubb1, and N. Ehrhart1

Boston University, Boston, MA, 2University of Auckland, Auckland, New Zealand, 3 University of Iowa, Iowa City, IA

1

1

P-Fri-516 An Analytical Theory of Oxygen Transport in the Human Placenta A. Serov1, C. Salafia2, D. Grebenkov1, and M. Filoche1 Ecole Polytechnique - CNRS, Palaiseau Cedex, France, 2Placenta Analytics LLC, Larchmont, NY

1

P-Fri-517 Estimation of Soft Tissue Elasticity surrounding Upper Airway from MR Imaging and Tube Law Method D. Subramaniam , G. Mylavarapu , R. Fleck , S. Shott , R. Amin , and E. Gutmark1 1

1

2

2

University of Cincinnati, Cincinnati, OH, 2Cincinnati Children's Hospital Medical Center, Cincinnati, OH

P-Fri-518 Aerosolized miR-146a Delivery and Expression in a Mouse Model C. Bobba1, K. Nelson1, B. Whitson1, X. Zhao1, and S. Ghadiali1 1

A. Carlson1, I. Shadrin1, and N. Bursac1 1

A. Meliton1, M. Allen1, K. Birukov1, M. Gardel1, M. Gardel1, and A. Birukova1 University of Chicago, Chicago, IL

Duke University, Durham, NC

P-Fri-235 Mechanosensors of Fluid Shear Induced MSC Migration B. Riehl1, J. Lee1, L. Ha1, and J. Lim1 1

University of Nebraska-Lincoln, Lincoln, NE

)

P-Fri-236 Optical Flow Paired With Machine Learning for Increased Detection of Drug-Induced Cardiotoxicity in Human Induced Pluripotent Stem Cell Derived Cardiomycoytes E. Lee1, Y. Kurokawa1, S. George1, and M. Khine1 1

The Ohio State University, Columbus, OH

P-Fri-519 Modulation of Lung Vascular Stiffening by Lipoxin Attenuates LPS-induced Lung Inflammation 1

P-Fri-234 Human Pluripotent Stem Cell Derived Cardiac Tissues for Drug Development and Disease Modeling

2

1

Colorado State University, Fort Collins, CO

University of California, Irvine, Irvine, CA

P-Fri-237 Role of the Stretch-activated Ion Channel Piezo1 in Mechanosensitive Lineage Choice M. Pathak1, J. Nourse1, T. Tran1, J. Arulmoli1, J. Hwe1, E. Bernardis2, L. Flanagan1, and F. Tombola1 1

UC Irvine, Irvine, CA, 2Children's Hospital of Philadelphia, Philadelphia, PA

P-Fri-520 Quantifying Effects of Upper Airway Shunt on Peripheral Heterogeneity: A Computational Model Study

P-Fri-238 Controlling Lineage Specific Differentiation Potential of Pluripotent Stem Cells by Engineering Colony Morphology

S. Bhatawadekar1, D. Leary 1, and G. Maksym1

M. Maldonado1, K. Low1, L. Wong1, G. Ico1, T. Fujimoto1, R. Luu1, and J. Nam1

1

Dalhousie University, Halifax, NS, Canada

1

P-Fri-239 Influence of Agitation Rate and Aggregate Size on Human Pluripotent Stem Cells in Dynamic Suspension

P-Fri-521 Effect of Lung Tissue Density on 18F-FDG Kinetics Parameters T. Wellman1 and M. Vidal Melo2 1

Boston University, Boston, MA, 2Massachusetts General Hospital, Boston, MA

D. Nampe1, R. Joshi1, C. Beaudette1, C. Liew1, and H. Tsutsui1 1

Mechanobiology and Stem Cell Translation

T. Block1, M. Marinkovic1, R. Rakian1, D. Dean1, and X-D. Chen1 1

Chairs: Thomas Gaborski, Janet Zoldan P-Fri-231 Distribution of Mitochondria in Human Mesenchymal Stem Cells during Endothelial Differentiation 1

2

2

1

M. Gurel1 and P. McFetrigde1 1

1 2 3

Department of Biomedical Engineering, Inje University, Gimhae, Korea, Republic of, Department of Health Science and Technology, Inje University, Gimhae, Korea, Republic of, Cardiovascular and Metabolic Disease Center/ Institute of Aged Life Redesign/UHRC, Inje University, Gimahe, Korea, Republic of

1 2 3

P-Fri-232 Texture Analysis of Nucleus during Differentiation of hMSCs into Osteoblasts in Early Phase

University of Texas Health Science Center at San Antonio, San Antonio, TX

P-Fri-241 Endothelial Differentiation of Adipose-derived Stem Cells in Comparison with Whartons jelly-derived Mesenchymal Stem Cells

J. Shin , S. Park , Y. Kang , S. Gu , H. Park , H. Kim , and J-W. Shin , , 1

University of California, Riverside, Riverside, CA

P-Fri-240 Characterization of Human Mesenchymal Stem Cell Populations From Old Donors

Track: Stem Cell Engineering

1

University of California, Riverside, Riverside, CA

University of Florida, Gainesville, FL

P-Fri-242 HT-MBOSS: A High-Throughput System for Studying Cellular Mechanobiology J. Lee1, E. Yoon1, J. Jansson1, A. Baker1, and M. Wong1 1

University of Texas at Austin, Austin, TX

S. Park1, J. Shin1, Y. Kang1, Y. Kim1, H. Park2, S. Gu2, and J-W. Shin1,2,3 Department of Biomedical Engineering, Inje University, Gimhae-si, Korea, Republic of, Department of Health Science and Technology, Inje University, Gimhae-si, Korea, Republic of, 3Cardiovascular and Metabolic Disease Center /Institute of Aged Life Redesign/UHRC, Inje University, Gimhae-si, Korea, Republic of

1 2

See page 141 for Poster floor plan

BMES 2014

167

Poster Session

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM

Track: Stem Cell Engineering, Biomaterials

Stem Cell Environments and Differentiation Chairs: Thomas Gaborski, Janet Zoldan P-Fri-110 Promoting Ligamentogenic Differentiation of Mesenchymal Stem Cells in Controlled Microenvironments M. Rehmann1 and A. Kloxin1 1

University of Delaware, Newark, DE

P-Fri-120 cancelled by author P-Fri-121 The Effect of Alginate Capsule Composition on Pancreatic Differentiation of Human Embryonic Stem Cells T. Richardson1, J. Candiello1, P. Kumta1, and I. Banerjee1 1

University of Pittsburgh, Pittsburgh, PA

P-Fri-122 Controlled Cell Transdifferentiation by Nanochannel Electroporation D. Gallego-Perez1, S. Ghatak1, J. Ma1, C. Czeisler1, P. Gygli1, T. Sherwood1, V. Malkoc1, L. Chang1, X. Wang1, C. Askwith1, S. Khanna1, C. Rink1, S. Gnyawali1, C. Sen1, J. Otero1, and L. Lee1 The Ohio State University, Columbus, OH

1

P-Fri-111 Determining the Physiochemical Cues Directing Endothelial Specification During Differentiation Q. Smith1 and S. Gerecht1 1

Johns Hopkins University, Baltimore, MD

P-Fri-123 Optimization of Alternating Electric Current to Achieve Osteodifferentiation of Adult Human Mesenchymal Stem Cells M. Wechsler1, B. Hermann1, and R. Bizios1 The University of Texas at San Antonio, San Antonio, TX

1

P-Fri-112 Arrayed Microenvironments for Probing Liver Progenitor Cell Fate Decisions K. Kaylan1, V. Ermilova1, and G. Underhill1 1

University of Illinois at Urbana-Champaign, Urbana, IL

P-Fri-124 Directed Differentiation of Stem Cells by 3D Extracellular Matrix Composites J. Jung1, M. Bache-Wiig1, and B. Ogle1 University of Minnesota - Twin Cities, Minneapolis, MN

1

P-Fri-113 Engineering the Cellular Lipidome to Direct Mesenchymal Stem Cell Differentiation K. Levental1, E. Stockenbojer2, and I. Levental1 University of Texas Health Science Center at Houston, Houston, TX, 2Rice University, Houston, TX

1

Poster Session

Fri

P-Fri-114 Expression of Extracellular Matrix and Cell-adhesion Molecules in Chondrogenesis of Human MSCs A. NAZEMPOUR1, C. R. Quisenberry1, N. Abu-Lail1, and B. J Van Wie1 Voiland School of Chemical Engineering and Bioengineering, Washington State University, PULLMAN, WA

1

P-Fri-115 Incorporation of Retinoic Acid Releasing Microspheres into Aggregates of Pluripotent Stem Cells for Inducing Neuronal Differentiation J. Gomez1, J. Edgar1, N. Mohtaram1, A. Montgomery1, and S. Willerth1 1

University of Victoria, Victoria, BC, Canada

P-Fri-116 Deterministic HOX Patterning in Human Pluripotent Stem Cell-derived Posterior Neuroectoderm E. Lippmann1, C. Williams1, M. Estevez-Silva1, J. Coon1, and R. Ashton1 1

University of Wisconsin, Madison, WI

P-Fri-117 Prediction of Drug-Induced Liver Injury in Engineered Cultures of iPSCDerived Human Hepatocytes B. Ware1, D. Berger1, and S. Khetani1 1

Colorado State University, Fort Collins, CO

P-Fri-118 Microfluidic Co-cultures to Study Stem Cell Fate Selection During Liver Injury A. Haque1, P. Gheibi1, Y. Gao1, and A. Revzin1 1

University of California, Davis, Davis, CA

)

P-Fri-119 Distinct Regulation Of Arterial Venous Differentiation By Ephrinb2/Ephb4 Hydrogels T. Dorsey1 and G. Dai1 1

Rensselaer Polytechnic Institute, Troy, NY

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

168

BMES 2014

P-Fri-125 Re-engineering The 3D Pancreatic Niche: Co-culture of Endothelial Cells with Human Embryonic Stem Cells-derived Pancreatic Progenitor Cells in Decellularized Pancreas S-K. Goh1, S. Bertera2, S. Barner1, and I. Banerjee1,3 University of Pittsburgh, Pittsburgh, PA, 2Children's Hospital of Pittsburgh, Pittsburgh, PA, McGowan Institute of Regenerative Medicine, Pittsburgh, PA

1 3

P-Fri-126 Micro-engineered ECM Array as a Platform for Deciphering Cell-ECM Interaction During Stem Cell Differentiation S-K. Goh1, S. Bertera2, W. Halfter1, and I. Banerjee1,3 University of Pittsburgh, Pittsburgh, PA, 2Children's Hospital of Pittsburgh, Pittsburgh, PA, McGowan Institute of Regenerative Medicine, Pittsburgh, PA

1 3

P-Fri-127 In vitro Vascular Arterial Differentiation of Embryonic Stem Cells through Neuropilin-1 D. Kim1 and G. Dai1 Rensselaer Polytechnic Institute, Troy, NY

1

P-Fri-128 A Kinase Inhibitor Screen Identifies Small-molecule Modulators During Human Pluripotent Stem Cell-derived Cardiac Progenitors into Cardiomyocytes H. Song1, M. Radisic2, and P. Zandstra2 University of Toronto, Toronto, ON, Canada, 2University of Toronto, Toronto, Canada

1

P-Fri-129 Cadherin-11 Directs Mesenchymal Stem Cell Differentiation and Regulates Extracellular Matrix Production and Mechanical Properties of Myogenic Tissues in-vivo and in vitro S. Row1, S. Alimperti1, M. Koobatian1, Y. Liu1, T. George2, S. Agarwal2, and S. Andreadis1 State University of New york at Buffalo, Amherst, NY, 2Baylor College of Medicine, Houston, TX

1

P-Fri-130 Directed Differentiation of Mesenchymal Stem Cells on Cross-linked Gelatin Scaffolds by Mechanical and Architectural Cues K. McAndrews1, F. Kim1, T. Lam1, D. McGrail1, and M. Dawson1 Georgia Institute of Technology, Atlanta, GA

1

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-131 A Multifactorial Approach Focusing On Induced Cardiomyocyte Transdifferentiation

P-Fri-68 Electrospinning of Dendrimers as a New Bio-Engineered Scaffold

N. Christoforou1,2, S. Chakraborty1, A. Adler1, and K. Leong1

1

Duke University, Durham, NC, 2Khalifa University of Science Technology and Research, Abu Dhabi, United Arab Emirates

1

P-Fri-132 Single-Cell Approaches to Assess Hematopoietic Stem Cell Response to Matrix Cues J. Choi1, Y. Ilin1, Y. Zhuo1, B. Cunningham1, M. Kraft1, and B. Harley1 1

University of Illinois at Urbana-Champaign, Urbana, IL

P-Fri-133 Protein Laden Soft Matrices as High-Throughput Platforms to Engineer Stem Cell Microenvironments M. Floren1, S. Bryant1, and W. Tan1 1

University of Colorado, Boulder, CO

P-Fri-134 Hematopoietic Stem and Progenitor Cells Provide a Local Source of Neutrophils Necessary to Resolve Infected Wounds P. Falahee1, D. Dahmubed1, and S. Simon1 1

University of California at Davis, Davis, CA

D. Aduba, Jr.1, J. Overlin1, C. Frierson1, G. Bowlin2, and H. Yang1 Virginia Commonwealth University, Richmond, VA, 2University of Memphis, Memphis, TN

P-Fri-69 Incorporation of Intervertebral Disc Cells into Candidate Materials for Nucleus Pulposus Regeneration E. Growney Kalaf1, K. Feltz1, N. Temofeew1, J. Bledsoe1, and S. Sell1 1

Saint Louis University, St. Louis, MO

P-Fri-70 Effects of Pore Size on Mechanical Properties and MSC Behavior in Bioglass Composite Scaffolds C. Vissers1 and J. Leach1 1

University of California, Davis, Davis, CA

P-Fri-71 Compressed Gelatin-Honey Sponges as Membrane Barriers for Bone Grafting Applications I. Rodriguez1, B. Burger2, and G. Bowlin1 The University of Memphis, Memphis, TN, 2Dulles Institute for Oral/Maxillofacial Surgery, Sterling, VA

1

P-Fri-72 Fabricating Highly Aligned Collagen Sponges From Self-Assembled, Fibrillar Collagen Gels

P-Fri-135 cancelled by author

C. Lowe1, I. Reucroft1, and D. Shreiber1 1

Track: Tissue Engineering, Stem Cell Engineering

Scaffolds and Surfaces for Tissue Engineering Chairs: Justin Brown, Lijie Grace Zhang P-Fri-63 Electrospun Nanostructured Chitosan/PVA Loaded with Growth Factors for Wound Healing M. Wang1 and T. Webster1,2 1

The northeastern university, Boston, MA, 2King Abdulaziz University, Jeddah, Saudi Arabia

P-Fri-64 Optimally Processed Porcine Adipose Tissue as a Soft Tissue Engineering Scaffold K. Roehm1 and S. Madihally1 1

Oklahoma State University, Stillwater, OK

P-Fri-65 Antibacterial Properties of Collagen Hydrogels with Tunable Mechanical Properties R. Egerter1, C. Angpraseuth1, M. Jimenez1, C. Keeler1, C. Stannard1, and E. Orwin1 1

Harvey Mudd College, Claremont, CA

P-Fri-66 Poly(ethylene) Glycol Diacrylate Scaffold Mimics Elasticity of Native Bruch's Membrane for Retinal Tissue Engineering C. White1 and R. Olabisi1 1

Rutgers, The State University of New Jersey, Piscataway, NJ

P-Fri-67 The Effects of Hydroxyapatite Size and Hydrostatic Pressure on Osteogeneis of MSCs in vitro S. Gu1, Y. Kang2, S. Park2, J. Shin2, Y. Wu2, and J-W. Shin1,2,3 Department of Health Science and Technology. Inje University, Gimhae-si, Korea, Republic of, 2Department of Biomedical Engineering, Inje University, Gimhae-si, Korea, Republic of, 3Cardiovascular and Metabolic Disease Center/Institute of Aged Life Redesign/UHRC, Gimhae-si, Korea, Republic of

1

Rutgers University, Piscataway, NJ

P-Fri-73 Synthesis and Evaluation of Barnacles β Strand Peptide Having Cell Attachment Activity K. Takase1, Y. Hirano1, and K. Kamino2 1

Kansai University, Suita, Japan, 2NITE, Chiba, Japan Poster Session

P-Fri-74 3D Printed Bone Scaffolds with Microvascular Network and Nano Hydroxyapatite for Improved hMSC Functions

Fri

B. Holmes1 and L. Zhang1 1

The George Washington University, Washington, DC

P-Fri-75 Delivery of Growth Factor via Two Electrospinning Techniques L. Place1, M. Seyki2, J. Taussig2, and M. Kipper2 1

Colorado State, Fort Collins, CO, 2Colorado State University, Fort Collins, CO

P-Fri-76 Endothelialization of Novel Magnesium-Rare Earth Alloys with Fluoride and Collagen Coating N. Zhao1, B. Workman1, J. Ma1, and D. Zhu1 1

North Carolina A&T State University, Greensboro, NC

P-Fri-77 A Pressure-sensitive Adhesive Derived from Sundew Plants for Wound Healing Y. Huang1, Y. Wang1, L. Sun1, and M. Zhang1 1

The Ohio State University, Columbus, OH

P-Fri-78 Characterization of Native Wharton's Jelly: A Natural Tissue Engineering Construct S. Sahai1, M. Wilkerson1, F. Vitale2, D. Tsentalovich2, S. Kiran1, M. Pasquali2, C. S. Cox Jr.1, and F. Triolo1 UTHealth – The University of Texas Health Science Center at Houston, Houston, TX, 2Rice University, Houston, TX

1

P-Fri-79 PEGylated Fibrin Biomaterials for Cardiomyocyte Cultivation A. Allen1, L. Geuss1, L. Suggs1, and J. Zoldan1 1

University of Texas at Austin, Austin, TX

See page 141 for Poster floor plan

BMES 2014

169

Friday | october 24 | 2014

Poster Session Fri 9:30am – 5:00pm

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM

P-Fri-80 Chitosan-Hyaluronic Acid Scaffolds As A Mimic Of Glioblastoma Microenvironment Extracellular Matrix

Track: Tissue Engineering

K. Wang , S. Florczyk , F. Kievit , and M. Zhang

Bioreactors for Tissue Engineering

1

1

1

1

1

University of Washington, Seattle, WA

P-Fri-81 Hydrogel Polymer Libraries for Developing Induced Pluripotent Stem Cell Derived Cardiac Patches A. Joaquin1, N. Peppas1, and J. Zoldan1 1

University of Texas at Austin, Austin, TX

P-Fri-82 Early in-vitro and in-vivo Characterization of Small Submucosa and Hyaluronic Acid 3D Scaffolds D. Tabima1, V. Talero1, A. Sabogal1, J. Navarro1, D. Narvaez1, H. Groot1, and R. Lopez1 1

Universidad de los Andes, Bogota, Colombia

P-Fri-83 A Preliminary Evaluation of Electrospun Polycaprolactone Scaffolds Embedded with Bioglass Beads for Dermal Repair R. Flores1, A. Mohammadkhah2, D. Day2, and S. Sell1 1

Saint Louis University, St Louis, MO, 2Missouri Science & Technology, Rolla, MO

P-Fri-84 Bi-Axially Aligned Nanofibers for Soft Tissue Regeneration B. Banik1 and J. Brown1 1

The Pennsylvania State University, University Park, PA

P-Fri-85 Fibrous HA Scaffolds With Active NGF Delivery For Directed Neurite Growth T. Whitehead1 and H. Sundararaghavan1 1

Poster Session

Fri

Wayne State University, Detroit, MI

)

P-Fri-86 A Three-Dimensional Model of Vascularized Human Tumor Colon Spheroids in a Human Colon-Extracted Extracellular Matrix M. Romero Lopez and C. Hughes 1

1

1

University of California Irvine, Irvine, CA

)

P-Fri-87 Cell Proliferation and Infiltration in Electrospun non-Synthetic BiopolymerBased Scaffolds D. Ardila1, E. Tamimi1, A. Acuña1, T. Doetschman1, and J. Vande Geest1 1

The University of Arizona, Tucson, AZ

)

P-Fri-88 Cell-derived Matrices as Biomimetic Substrates for Cardiomyoblast Differentiation M. Suhaeri1,2, M. Hwang1, I. Kim1, S. Van1,2, and K. Park1,2 Korea Institute of Science and Technology, Seoul, Korea, Republic of, 2University of Science and Technology, Daejon, Korea, Republic of

1

Chairs: Anuradha (Anu) Subramanian, Teja Guda

)

P-Fri-255 Development Of A Graft For Skeletal Muscle Regeneration Using Bioreactor Technology B. Pollot1,2, C. Rathbone2, and T. Guda1,2 University of Texas at San Antonio, San Antonio, TX, 2U.S. Army Institute of Surgical Research, Ft. Sam Houston, TX

1

P-Fri-256 Simulated Microgravity Can Alter Cell Viability, Density, and Transport in 3D Microtissues E. Evans1, Y-T. Dingle1, and D. Hoffman-Kim1 1

Brown University, Providence, RI

P-Fri-257 Theoretical Modeling and Experimental Verification of an Ultrasound Assisted Bioreactor T. Louw1, H. Viljoen2, and A. Subramanian2 1

University of Cape Town, Cape Town, South Africa, 2University of Nebraska, Lincoln, NE

P-Fri-258 Bioreactor Technologies and Testing of Stem Cell-Seeded Scaffolds for Tissue Engineered Heart Valves L. Sierad1,2, E. Shaw1, A. Kennamer1, R. Odum1, M. Harpa2, O. Cotoi2, T. Preda2, L. Harceaga2, R. Deac2, V. Raicea2, H. Suciu2, K. Branzaniuc2, I. Egyed2, Z. Pavai2, A. Szanto2, A. Simionescu1,2, and D. Simionescu1,2 Clemson University, Clemson, SC, 2Targu Mures University of Medicine and Pharmacy, Targu Mures, Romania

1

P-Fri-259 Quantification of Mechanically Induced Orientation of Collagen Fibers in Tissue Engineered Cartilage E. Kahn1, R. Stefani2, M. Kelley1, A. Mei1, and B. Bilgen2,3 Brown University, Providence, RI, 2The Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, RI, 3Providence VA Medical Center, Providence, RI

1

P-Fri-260 Effects of Phonation-Relevant Vibration on Macrophage Phagocytosis A. Zerdoum1, B. Bachman1, and X. Jia1 University of Delaware, Newark, DE

1

P-Fri-261 Identifying the Localized Shear Forces on Cultured Preosteoblasts in 3D Flow Perfusion Cultures and Elucidating Their Metabolic State V. Sikavitsas1, C. Williams1, R. Voronov2, and D. Papavassiliou1 University of Oklahoma, Norman, OK, 2New Jersey Institute of Technology, Newark, NJ

1

P-Fri-262 H-Bioreactor Design,Viability Analysis, And Characterization Of Strain On Corneal Keratocytes T. Beckman1, R. Roley1, and E. Orwin1 Harvey Mudd College, Claremont, CA

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

170

BMES 2014

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM

Track: Tissue Engineering

Blood Vessel Tissue Engineering Chairs: Wei Tan, Hsiai Tzung P-Fri-263 Self-assembly of Endothelial Cells and Smooth Muscle Cells in Bio-printed 3D Fluidic Vascular Tissue V. Lee1, P. Vincent2, S-S. Yoo3, and G. Dai1 Rensselaer Polytechnic Institute, Troy, NY, 2Albany Medical College, Albany, NY, 3Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 1

P-Fri-264 Fabrication of Perfused Culture System for Functional Microvasculature Models Y. Yukawa , B. Kim , and Y. Matsunaga 1

1

1

1

Institute of Industrial Science, The university of Tokyo, Meguro-ku, Tokyo, Japan

P-Fri-265 Large-scale Functional Endothelialized Microvessels in a Gel-free Microfluidic Network Y. Xiao1, M. Xu2, X. Zi1, X. Li3, G. Zheng2, J. Fu3, S. Halene1, R. Fan1, L. Niklason1, and J. Zhou1 1 3

Yale University, New Haven, CT, 2Fudan University, Shanghai, China, People's Republic of, University of Michigan, Ann Arbor, Ann Arbor, MI

P-Fri-266 Reliable Soft Thermo-responsive Substrates for Patterned Cell-Sheet Engineering S. Shah , D. Backman , B. LeSavage , and J. Wong 1

1

1

1

Boston University, Boston, MA

H. Patel1, V. Thomas1, S. Pogwizd1, R. Singh2, and Y. Vohra1 University of Alabama at Birmingham, Birmingham, AL, 2Vivo Biosciences, Birmingham, AL

P-Fri-268 Adipose Derived Stem Cells for a Vascular Graft University of Oklahoma, Norman, OK

University of Houston, Houston, TX

P-Fri-270 Development of Collagen Type IV Immobilized Electrospun PLLA Nanofibers Using Gamma-ray Irradiation for Enhanced Endothelialization H. Yunhoe1,2, L. Yu Bin1,2, L. Jang-Soo1,2, K. Eunmi1,2, and S. Heungsoo1,2 Hanyang University, Seoul, Korea, Republic of, BK Plus Future Biopharmaceutical Human Resources Training and Research Team, Seoul, Korea, Republic of 2

21

P-Fri-271 Increased Elastin Matrix Production In PEG-diacrylate Hydrogels For Vascular Tissue Engineering D. Holman1, N. Nosoudi1, H-J. Lee1, K. Webb1, and N. Vyavahare1 1

Clemson University, Clemson, SC

J. Soares1 and M. Sacks1 1

University of Texas at Austin, Austin, TX

P-Fri-588 Porcine Pericardium Fixation Studies For Aortic Heart Valves In Pediatrics T. Welch1, J. Wang1, K. Guleserian1, V. Sebastian1, and J. Forbess1 1

UT Southwestern Medical Center of Dallas, Dallas, TX

P-Fri-589 Development of a Tissue Engineered Mitral Valve C. deBorde1, J. Liao2, D. Simionescu1, and A. Simionescu1 1

Clemson University, Clemson, SC, 2Mississippi State University, Mississippi State, MS

P-Fri-590 Design of a Hypoxic Incubator for the Study of Calcific Aortic Valve Disease M. Sapp1, G. Fatora1, and K. Grande-Allen1 1

Rice University, Houston, TX

)

P-Fri-591 Electrical Pacing Of 3D IPSC-Derived Cardiomyocytes In A Microfluidic Device S. Lam1, M. Simon1, D. Tran1, L. Alonzo1, N. Flohn1, A. Lee1, and S. George1 1

1

M. Mohamed1, M. Hogan1, N. Patel1, Z-W. Tao1, and R. Birla1

1

P-Fri-587 Modeling the Enhancement of Extracellular Matrix Quantity and Quality in Large-Deformation Mechanically-Conditioned Heart Valve Tissue Engineering

University of California, Irvine, Irvine, CA

J. Wendel1 and R. Tranquillo1

P-Fri-269 Development of a Bioengineered Cardiac Assist Device 1

Chairs: Jeffrey Jacot, Dan Simionescu

P-Fri-592 Engineered Cardiac Tissues Utilizing Human Induced Pluripotent Stem CellDerived Cardiomyocytes

J. Arrizabalaga1 and M. Nollert1 1

Cardiac Muscle and Valve Tissue Engineering

1

P-Fri-267 A Novel Bio-hybrid Functionally Graded Small Diameter Vascular Graft 1

Track: Tissue Engineering, Cardiovascular Engineering

University of Minnesota, Minneapolis, MN

P-Fri-593 Human Pediatric Cardiac Progenitor Cells Formed Structures with High Alignment in 3D Culture Y. Gao1 and J. Jacot1,2 1

Rice University, Houston, TX, 2Texas Children’s Hospital, Houston, TX

P-Fri-594 Fabrication and Formation of Multi-Strip, Optogenetic Cardiac Muscles V. Chan1, D. Neal1, and H. Asada1 1

Massachusetts Institute of Technology, Cambridge, MA

P-Fri-595 Human Mesenchymal Stem Cell Seeding of Porcine Small Intestinal Submucosal Extracellular Matrix J. Chang1, X. Lin2, T. Petrie2, C. Sondergaard2, and L. Griffiths1 1

University of California-Davis, Davis, CA, 2University of California-Davis, Sacramento, CA

See page 141 for Poster floor plan

BMES 2014

171

Poster Session

Fri

Poster Session Fri 9:30am – 5:00pm

Friday | october 24 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM, 4:00PM - 5:00PM P-Fri-252 Effect of MSC and Fibrochondrocyte 3D Co-Culture on Matrix Secretion and Cell Phenotype

Track: Tissue Engineering, Stem Cell Engineering

M. McCorry1, J. Puetzer1, and L. Bonassar1

Tissue Microfabrication and Stem Cells Chairs: Min-Ho Kim,Ying Mei P-Fri-243 Construction of 3D Engineered Tissue by Magnetically-Assisted Cell Assembly 1 2

1 2

1 2

Hanyang University, Seoul, Korea, Republic of, 2BK21 Plus Future Biopharmaceutical Human Resources Training and Research Team, Seoul, Korea, Republic of

P-Fri-244 A Single Mask, Single Etch Process for Fabricating 3-D Geometries in Collagen I Hydrogel Y. Hosseini1, S. Verbridge1, and M. Agah1 Virginia Tech, Blacksburg, VA

P-Fri-245 Projection Micro-Stereolithography Apparatus for High Resolution Patterning of Cells in 3D: Applications in Tissue Engineering of Vasculature R. Raman1, B. Bhaduri1, A. Shkumatov1, K. Baek1, M. Mir2, H. Kong1, G. Popescu1, and R. Bashir1 University of Illinois at Urbana-Champaign, Champaign, IL, 2University of California, Berkeley, Berkeley, CA

1

P-Fri-246 3D Printing of Hydrogel Scaffolds with Tailored Composition and Stiffness K. Homan , A. Jagielska , R. Hawthorne , T. Busbee , K. Van Vliet , and J. Lewis1 1

2

1

1

2

Harvard University, Cambridge, MA, 2MIT, Cambridge, MA

1

Poster Session

Fri

P-Fri-247 Engineering Alginate Microfibers with Spatially Defined Fibronectin Functional Sites for Skeletal Muscle Tissue Engineering J. Szymanski , P. Patil , and A. Feinberg 1

1

1

Carnegie Mellon University, Pittsburgh, PA

1

P-Fri-248 Investigating Endothelial Remodeling in Tissue-Engineered Microvessels via RNA-seq J. Zhou1, M. Xu1,2, X. Zi1, Y. Xiao1, G. Zheng2, L. Niklason1, and R. Fan1,3 Yale University, New Haven, CT, 2Fudan University, Shanghai, China, People's Republic of, Yale Comprehensive Cancer Center, New Haven, CT

1 3

P-Fri-249 Exploiting Angiogenic Properties of Dedifferentiated Fat Cells M. Shah1, M. Chapman2, R. George2, V. Narayan3, and G. Zhang1 University of Akron, Akron, OH, 2Summa Health System, Akron, OH, 3The Austen BioInnovation Institute in Akron, Akron, OH

1

P-Fri-250 Enhanced Stem Cell Growth on Smart Polyurethane Scaffolds N. Castro1, K. Hearon2, and L. Zhang1 The George Washington University, Washington, DC, 2Massachusetts Institute of Technology, Cambridge, MA 1

P-Fri- 253 Mechanical Stimulation Of PEGDA Encapsulated Mesenchymal Stem Cells Into Adipocytes 1

1 2

1

1

Cornell University, Ithaca, NY

S. Mehta1 and R. Olabisi1

L. Yu Bin , , L. Joong-yup , , T. Ahmad , , B. Seongwoo , , and S. Heungsoo , 1 2

1

Rutgers University, New Brunswick, NJ

P-Fri-254 Potential Effects of Mechanical Stimulation on The Reprogramming Somatic Cells into iPS Cells Y. Kim1, Y. Kang1, S. Park1, J. Shin1, S. Gu2, H. Park1, and J-W. Shin1,2,3 Department of Biomedical Engineering, Inje University, Gimhae-si, Korea, Republic of, 2Department of Health Science and Technology, Gimhae-si, Korea, Republic of, Cardiovascular and Metabolic Disease Center /Institute of Aged Life Redesign/UHRC, Gimhae-si, Korea, Republic of

1

3

Track: Translational Biomedical Engineering, Device Technologies and Biomedical Robotics

Translational Biomedical Engineering I Chairs: Mehdi Nikkhah, Mark Van Dyke

)

P-Fri-211 Amplification-free Multiplexed Detection of miRNA Biomarkers in Single Cancer Cells N. Wang1, Y. Wu1, Y. Lu1, S. Chapin2, P. Doyle2, and R. Fan1,3 1 Yale University, New Haven, CT, 2MIT, Cambrige, MA, 3Yale Comprehensive Cancer Center, New Haven, CT

P-Fri-212 Targeted Delivery Of Anti-miR-712 By VCAM1-Binding Au Nanospheres For Atherosclerosis Therapy R. Simmons1, T. Sun1, C. Kim1, X. Zhao1, Y. Xia1, and H. Jo1 1

P-Fri-213 Rapid, Single Bacterial Detection From Blood using Microencapsulated Sensors D-K. Kang1, M. Ali1, B. Fan1, K. Zhang1, I. Altamore1, M. Digman1, E. Gratton1, E. Peterson1, and W. Zhao1 1

P. Krzyszczyk1 and R. Olabisi1 1

Rutgers, The State University of New Jersey, Piscataway, NJ

Y. Cao1, C. Henry1, A. Bruce1, S. Peirce1, and K. Laughon1 1

)

172

BMES 2014

Univ. of Virginia, Charlottesville, VA

P-Fri-215 Bioactive Hydrogel Coatings for Improvised Titanium Implants S. Karnik1, Y. Luo1, U. Jammalamadaka1, K. Tappa2, and D. Mills1 Louisiana Tech University, Ruston, LA, 2Louisiana Tech University, Ruston, Afghanistan

P-Fri-216 Development of Silk-Elastinlike Protein Polymers as Liquid-To-Solid Embolic Agents A. Poursaid1, R. Price1, A. Tiede1, E. Olson1, E. Huo1, H. Ghandehari1, and J. Cappello1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

University of California-Irvine, Irvine, CA

P-Fri-214 In Vivo Validation of Fluorescent Dye to Detect Ano-genital Injury in Women

1

P-Fri-251 Growth Factor Release from Mesenchymal Stem Cells Encapsulated in PEGDA Microspheres

Georgia Institute of Technology & Emory University, Atlanta, GA

University of Utah, Salt Lake City, UT

9:30am – 5:00pm Poster Session Fri

2014 | october 24 | Friday

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM , 4:00PM - 5:00PM P-Fri-217 The Effect of Laser Adjuvant on the Efficacy of a Prophylactic Transcutaneous Influenza Vaccine

P-Fri-226 Multipotent Progenitor and Endothelial Cell Interactions Promote Angiogenesis and Osteogenesis

E. Elenes1, R. Jadi1, J. Deventhiran1, H. Sooryanarain1, S. Elankumaran1, and C. Rylander1

H. Hofer1, P. Alexander1, and R. Tuan1

1

Virginia Polytechnic Institute and State University, Blacksburg, VA

P-Fri-218 Development of a Hepatocyte Bioreactor Utilizing Perfusion through Aligned Nanofiber Networks A. Gill1, F. Popovic1, C. Brouse1, J. Moore1, T. Raisch1, B. Koons1, and A. Nain1 1

Virginia Tech, Blacksburg, VA

P-Fri-219 Silk Microneedle Delivery and Stabilization of Enteric Disease Vaccines W. Raja1, S. Lee2, H. Kim2, B. Xu2, B. Panilaitis1, S. Tzipori2, and D. Kaplan1 1

Tufts University, Medford, MA, 2Tufts University, North Grafton, MA

P-Fri-220 Microtopographies Inhibit Human Lens Epithelial Cell Migration in Posterior Capsule Opacification Model C. Kirschner1, M. Drinker1, K. Cuevas2,3, A. Brennan1,4, and S. Reddy1 1 3

Sharklet Technologies, Inc., Aurora, CO, 2Rocky Mountain Ophthamology, Golden, CO, Insight Innovations, LLC, Golden, CO, 4University of Florida, Gainesville, FL

Track: Translational Biomedical Engineering, Device Technologies and Biomedical Robotics

1

University of Pittsburgh, Pittsburgh, PA

P-Fri-227 A Novel Cell-Based Assay for MMP Inhibitor Screening P. Krisanarungson1, A. Walker1, and J. Wolchok1 1

University of Arkansas, Fayetteville, AR

P-Fri-228 PolyGraphene Muco-adhesive Medi-Patches for Anti-Stem like Cell Therapy via STAT-3 Inhibition S. Misra1,2 and D. Pan1,2 University of Illinois at Urbana-Champaign, Urbana, IL, 2Carle Foundation Hospital, Urbana, IL

1

P-Fri-229 Pathology Evaluation and Analysis of Cardiac Leads H. Smith1, S. Jessen1, T. Lancon1, M. O'Brien1, L. Suarez1, M. Wilcox1, M. Miller2, B. Weeks1, and F. Clubb, Jr.1 Texas A&M University, College Station, TX, 2Texas A&M Institute for Preclinical Studies, College Station, TX

1

P-Fri-230 Minimally Invasive Irreversible Electroporation For Pancreatic Cancer Treatment L. Reese1, J. McGuire1, G. Mishra2, C. Williams1, R. Davalos1, and L. Bickford1 1

Virginia Tech, Blacksburg, VA, 2Wake Forest Medical Center, Winston Salem, NC

Translational Biomedical Engineering II Chairs: Manu Platt, Mehdi Nikkhah P-Fri-221 Soy Scaffolds Improve Healing of Full Thickness Skin Excision Wounds in Rat and Pig Models

Poster Session

Fri

Y-E. Har-el1, J. Gerstenhaber1, S. Baharlou1, T. Lo1, R. Brodsky1, R. Huneke2, and P. Lelkes1 1

Temple University, Philadelphia, PA, 2Drexel University College of Medicine, Philadelphia, PA

P-Fri-222 The Analysis of Explanted Organ Perfusion to Determine Optimal Perfusion Temperature T. O'Brien1, T. Diller1, and J. Robertson1 1

Virginia Tech, Blacksburg, VA

P-Fri-223 Successful Isolation of Human islets using a Collagenase free Osmotic Shock Method J. McQuilling1,2, S. Sittadjody2, J. Steinman2, G. Orlando2, A. Farney2, and E. Opara1,2 Virginia Tech-Wake Forest School of Biomedical Engineering & Sciences (SBES), WinstonSalem, NC, 2Wake Forest School of Medicine, Winston-Salem, NC

1

P-Fri-224 Combined MicroRNA/Anti-MicroRNA Therapy and Molecular Beacons Based Prognosis of Mouse Hepatocelluar Carcinoma (HCC) using Target Lipoplex Nanoparticles X. wang1, Z. Yang1, R. Lee1, S. Jacob1, K. Ghoshal1, and J. Lee1 1

the Ohio State University, columbus, OH

P-Fri-225 Layer-by-layer Nanoparticles for Co-delivery of Chemodrugs and RNAi for Treating Aggressive Types of Cancers J. Deng1, S. Morton1, E. Dreaden1, and P. Hammond1 1

MIT, Cambridge, MA

See page 141 for Poster floor plan

BMES 2014

173

Saturday | OCTOBER 25 | 2014

Platform Sessions Sat-1 8:00AM-9:30aM

SATURDAY, October 25, 2014

TODAY’S HIGHLIGHT PLATFORM SESSION Sat 1

8:00am - 9:30am

See pages 174-181, HBGCC

EXHIBIT HALL OPEN

9:30am - 1:30p

8:00 AM - 9:30 AM PLATFORM SESSIONS – Sat - 1

POSTER SESSION SAT

Track: Tissue Engineering, Cardiovascular Engineering OP-Sat-1-1 - Room 001A

& Refreshment Break

Cardiac Muscle and Valve Tissue Engineering

HBGCC, Exhibit Hall A

9:30pm -1:00pm See pages 195-210 HBGCC, Exhibit Hall A Poster Viewing with Authors 9:30am - 10:30am

Chairs: Nenad Bursac, Song Li

PLENARY SESSION 10:30am - 12:30pm HBGCC, Lila Cockrell Theatre

Rita Schaffer Memorial Young Invesigator Lecture

8:00AM

Tubular Heart Valves by Suturing Decellularized Engineered Tissue Tubes J. Reimer1, Z. Syedain1, B. Haynie1, and R. Tranquillo1 1

University of Minnesota, Minneapolis, MN

New Paradigms for Cell Migration in Confined Microenvironments

8:15AM

Kimberly Stroka, PhD

C. Jackman1 and N. Bursac1

Electrically Stimulated Heart Microbundles as a 3D Model of Neonatal to Adult Cardiac Tissue Maturation 1

Diversity Lecture Naomi Chesler, PhD

Fibrous Tissue Scaffolds: Relationships between Geometric Structure and Mechanical Behavior J. Carleton1, G. Rodin1, and M. Sacks1

PLATFORM SESSION Sat 2

1:30pm - 3:00pm

PLATFORM SESSION Sat 3

3:15pm - 4:15pm

See pages 182-188, HBGCC See pages 189-193, HBGCC

Duke University, Durham, NC

8:30AM

1

University of Texas at Austin, Austin, TX

8:45AM

Three-Dimensional Artificial Heart Muscle to Supplement the Framework of a Bioartificial Heart M. Hogan1, M. Mohamed1, Z-W. Tao1, L. Gutierriez1, and R. Birla1 1

University of Houston, Houston, TX

9:00AM

Platform Sessions

Tuning Material Properties of Cardiac Extracellular Matrix for Cardiac Tissue Engineering

Sat-1

M. Jeffords1, J. Wu2, Q. Ding2, Y. Hong2, and G. Zhang1 1

The University of Akron, Akron, OH, 2University of Texas at Arlington, Arlington, TX

9:15AM

Native Fiber Structure in Decellularized Myocardium Promotes Cardiac Cell Alignment and Maturation J. Schwan1, A. Kwaczala1, T. Ryan1, A. Lebid1, and S. Campbell1 1

Yale University, New Haven, CT

Track: Biomaterials, Nano to Micro Technologies OP-Sat-1-2 - Room 001B

Micro and Nanostructured Materials Chairs: Scott Verbridge, Tzahi Cohen-Karni 8:00AM

Tunable Microtopography Reduces Myofibroblast Activation and Cutaneous Fibrosis J. Allen1, J. Ryu1, and T. Desai1 1

University of California, San Francisco, San Francisco, CA

8:15AM

Heat-Resistant RNA Biomaterials to Construct Nanoparticles with Controllable Size, Shape, and Stoichiometry for Biomedical Applications E. Khisamutdinov1, D. Jasinski1, and P. Guo1 P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

174

BMES 2014

Nanobiotechnology Center, Markey Cancer Center, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY

1

8:00AM-9:30am Platform Sessions Sat-1

2014 | OCTOBER 25 | Saturday

8:30AM

2D Nanosheets for Osteogenic Differentiation of Human Mesenchymal Stem Cells J. Xavier , P. Desai , and A. Gaharwar 1

1

1

1

Cardiovascular Biomechanics I

Texas A&M University, College Station, TX

8:45AM

Antigen-Independent Targeting of Cancer Cells on Polylysine/Fatty Acid Complexes C. Castellanos1, J. Li1, M. Mitchell1, and M. King1 1

Cornell, Ithaca, NY

Heparin Hydrogel Microdroplets for Cultivation of Embryonic Stem Cells C. Siltanen1, E. Foster1, J. You1, A. Haque1, D-S. Shin1, and A. Revzin1

8:00AM

Biomechanical Characterizations Of Scar ECM During The Acute To Chronic Stages Of Myocardial Infarction

3

Mississippi State University, Mississippi State, MS, 2Ohio State University, Columbus, OH, University of Akron, Akron, OH

Bending and Twisting the Embryonic Heart Tube: A Noval Computational Model

9:15AM

Biocompatible Sub-100 nm Patterning TiO2 for the Regulation of Endothelial and Smooth Muscle Cell Functions M. Rizwan , S. Lim , S. Goh , J. Law , M. Saifullah , G. Ho , and E. Yim 1

1

8:15AM

UC Davis, Davis, CA

1

Chairs: Hanjoong Jo, Danial Shahmirzadi

B. Brazile1, J. Butler1, S. Patnaik1, Y. Xu2, A. Claude1, R. Prabhu1, L. Williams1, G. Zhang3, J. Guan2, and J. Liao1

9:00AM

1

Track: Biomechanics, Cardiovascular Engineering OP-Sat-1-4 - Room 006B

1

2

2

1

Y. Shi1, J. Yao2, R. Perucchio3, and L. Taber1 1 3

1

National University of Singapore, Singapore, Singapore, 2Institute of Materials Research and Engineering, Singapore, Singapore

1

Track: Cardiovascular Engineering OP-Sat-1-3 - Room 006A

Microcirculation

Washington University, St. Louis, MO, 2Dassault Systemes Simulia Corp., Providence, RI, University of Rochester, Rochester, NY

8:30AM

Quantitative Histomorphological Analysis of Right Ventricular Myocardium Under Chronic Pressure Overload S. M. Siegel1, U. A. Dar1, M. Rahman1, M. R. Hill1, M. A. Simon2, and M. S. Sacks1 1

The University of Texas at Austin, Austin, TX, 2The University of Pittsburgh, Pittsburgh, PA

8:45AM

Exogenous Relaxin Treatment Reverses Left Ventricular Fibrosis and Improves Diastolic Function in a Rate Model

Chairs: Taby Ahsan, Steven George 8:00AM

J. Haney1, D. Schwartzman1,2, and S. Shroff1

A. Bruce1, M. Kelly-Goss1, J. Meisner1, R. Price1, and S. Peirce1

9:00AM

Monocytes are Recruited From Post-Capillary Venules During the Early Phases of Arteriogenesis 1

Univ. of Virginia, Charlottesville, VA

8:15AM

The Role Of Cathepsin B In The Control Of Neutrophil Pseudopod Activity Under Flow M. Akenhead1 and H. Shin1 1

University of Pittsburgh, Pittsburgh, PA, 2University of Pittsburgh Medical Center, Pittsburgh, PA

1

Time-Evolving Growth and Remodeling Response of Right Ventricular Myocardium to Pressure Overload M. Hill1, M. Simon2, and M. Sacks1 1

Platform Sessions

University of Texas at Austin, Austin, TX, 2University of Pittsburgh, Pittsburgh, PA

9:15AM

Probing Local Nonlinear Mechanics with Whole-Tissue Experiments

University of Kentucky, Lexington, KY

C. Witzenburg and V. Barocas 1

8:30AM

Flow Characteristics of Sickle Cell Blood in Hypoxic Conditions

1

1

University of Minnesota, Minneapolis, MN

X. Lu1, C. Jonas1, J. Higgins2,3, and D. Wood1 University of Minnesota, Minneapolis, MN, 2Harvard Medical School, Boston, MA, Massachusetts General Hospital, Boston, MA

1 3

8:45AM

Vein-On-a-Chip: Functional Assessment and Activation of Intact Mouse Mesenteric Vein Z. Abdi Dezfooli1, S-S. Bolz1, and A. Günther1

Track: Cellular and Molecular Bioengineering OP-Sat-1-5 - Room 006C

Cell and Molecular Immunoengineering Chairs: Lance Kam, Chris Love 8:00AM

University of Toronto, Toronto, ON, Canada

1

9:00AM

Exogenous Nitric Oxide Supplementation To Enhance The Outcome Of Fluid Resuscitation From Hemorrhagic Shock J. Crump1, J. Briceno1, and P. Cabrales2

Lipopolysaccharide (LPS) Induces the Interactions of Breast Cancer and Endothelial Cells via Activated Monocytes C. Chen1 and D. Khismatullin1 1

Tulane University, New Orleans, LA

Universidad de Los Andes, Bogota D.C., Colombia, University of California, San Diego, La Jolla, CA

8:15AM

9:15AM

B. Jones1, S. Mueller1, R. O'Connor1, V. Vrbanac1, A. Tager1, B. Walker1,2, and D. Irvine1,2

1

2

Platelet GpIbα Binding to Von Willebrand Factor (VWF) under Hydrodynamic Shear: Relative Contributions of The D’D3-domain, A1-domain Flanking Peptide and O-linked Glycosylation

T-Pharmacytes for the Targeted Eradication of Latent HIV Reservoirs Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 2Howard Hughes Medical Institute, Chevy Chase, MD

1

C. Zhang1, A. Kelkar1, S. Madabhushi1, K. Dayananda1, and S. Neelamegham1 1

SUNY at Buffalo, Buffalo, NY

BMES 2014

175

Sat-1

Saturday | OCTOBER 25 | 2014

Platform Sessions Sat-1 8:00AM-9:30aM

8:30AM

TLR3 Stimulation Enhances The Immune Stimulatory Properties of Exosome-based Vaccines M. Damo1, E. Simeoni1, D. Wilson1, and J. Hubbell1 1

Hepatic Cell-Mediated Delivery of Trefoil Factor 3 to Ischemic Myocardium - A Trans-system Mechanism Against Cardiomyocyte Calcification S. Liu1, B. Zhang1, and Y. Wu1

Swiss Federal Institute of Technology, Lausanne, Switzerland

1

8:45AM

Development of a Tissue-Engineered Lymph Node to Study Stromal Immunomodulatory Functions In Vitro C. Buchanan1 and M. Swartz1 1

9:15AM

Ecole Polytechnique Federal de Lausanne, Lausanne, Switzerland

Northwestern University, Evanston, IL

Track: Stem Cell Engineering, Biomechanics OP-Sat-1-7 - Room 007A

Mechanobiology of Stem Cells

9:00AM

Molecular-level Deconvolution of the Human Serum Antibody Repertoire Elicited by Vaccination

Chairs: Rhima Coleman, Shyni Varghese

J. Lavinder , G. Ippolito , Y. Wine , D. Boutz , J. Blazeck , A. Horton , C. Giesecke2, K. Hoi1, B. Tan1, E. Murrin1, M. Wirth1, A. Ellington1, T. Dörner2, E. Marcotte1, and G. Georgiou1

Nuclear Scaling in Stem Cell Differentiation

1

1

1

1

1

1

University of Texas at Austin, Austin, TX, Charite Universitätsmedizin Berlin, Berlin, Germany

1

2

D. Discher1 1

Univ Pennsylvani, Philadelphia, PA

8:30AM

9:15AM

Dysregulated Sphingolipid Metabolism In Sickled Erythrocytes & Inflammatory Microparticle Generation A. Awojoodu1, P. Keegan1, A. Lane1, Y. Zhang1, M. Platt1, and E. Botchwey1 1

8:00AM Invited

Georgia Institute of Technology, Atlanta, GA

ColVI and DCN's Role In Mechanotransduction And Scaffold Material Properties During Chondrogenesis J. Twomey1, B. Bulka1, and A. Hsieh1,2 University of Maryland, College Park, College Park, MD, 2University of Maryland, Baltimore, Baltimore, MA

1

8:45AM

Differentiation of Human Adipose-Derived Stem Cells in Response to Mechanical Stimulation

Track: Cardiovascular Engineering, Tissue Engineering OP-Sat-1-6 - Room 006D

K. Megerle1, W. Cole2, I. Mahaffey2, P. Leucht1, J. Chang1, and A. Castillo1,2 1

Cardiac Regeneration

9:00AM

Hippo-YAP Dependent Mechanosensitive Motor Neuron Differentiation of Human Pluripotent Stem Cells

Chairs: Milica Radisic, Lauren Black III 8:00AM

Designing an Elastic Scaffold with Shape-Memory for Functional Tissue Delivery M. Montgomery1, B. Zhang1, L. Reis1, and M. Radisic1 Platform Sessions

Sat-1

1

Y. Sun1, K. Aw Yong1, W. Chen1, R. Philson1, S. Weng1, and J. Fu1 1

University of Michigan, Ann Arbor, MI

9:15AM

Parsing Stem Cell Phenotypes Using High Content Imaging of Mechanotransductive Nuclear Reporters

University of Toronto, Toronto, ON, Canada

8:15AM

Generation of Functional Human Myocardium from Native Human Heart Matrix and Human iPS-derived Cardiomyocytes J. Guyette1, J. Charest1, P. Moser1, and H. Ott1 1

Stanford University School of Medicine, Palo Alto, CA, 2VAPAHCS, Palo Alto, CA

Harvard Medical School, Boston, MA

A. Dhaliwal1, S. Vega1, V. Arvind1, M. Brenner1, Z. Zhang2, Y. Mao2, J. Kohn3, and P. Moghe1,4 Biomedical Engineering, Rutgers University, Piscataway, NJ, 2New Jersey Center for Biomaterials, Rutgers University, Piscataway, NJ, 3Department of Chemistry & Chemical Biology, Rutgers University, Piscataway, NJ, 4Department of Chemical & Biochemical Engineering, Rutgers University, Piscataway, NJ

1

8:30AM

Engineering Mature Cardiac Tissue In Vitro: Biomechanical and Biochemical Stimulation of Physiological Hypertrophy. C. Rupert1, M. Regnier2, C. Murry2, and K. Coulombe1 1

Brown University, Providence, RI, 2University of Washington, Seattle, WA

Angiogenesis

8:45AM

In Vitro Recruitment of Macrophages by Human Embryonic Stem Cell-Derived Cardiomyocytes The New York Stem Cell Foundation Research Institute, New York, NY

1

Cardiac Progenitor Cell Exosomes to Treat the Heart S. Ghosh- Choudhary , W. Gray , K. Kanter , B. Kogon , M. Platt , and M. Davis4 1

2

3

3

2

Georgia Institute of Technology, Atlanta, GA, Georgia Insititute of Technology and Emory University, Atlanta, GA, 3Children's Healthcare of Atlanta, Atlanta, GA, 4Georgia Insititute of Technology and Emory University and Children's Healthcare of Atlanta, Atlanta, GA

1

2

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

176

BMES 2014

8:00AM

L. Deveza1, J. Choi1, J. Ashoken2, and F. Yang1

9:00AM

)

Chairs: Bob Tranquillo, Sara Nunes Vasconcelos

Recruitment and Programming of Endogeneous Progenitor Cells In Situ for Therapeutic Angiogenesis

I. Pallotta1, E. Wrona1, and D. Freytes1 1

Track: Cardiovascular Engineering OP-Sat-1-8 - Room 007B

Stanford University, Stanford, CA, 2San Jose State University, San Jose, CA

8:15AM

Uncoupling Angiogenesis and Inflammation in Peripheral Artery Disease by Therapeutic Peptides with Injectable Microgels A. Zachman1, X. Wang1, J. Tucker-Schwartz1, S. Lee1, M. Skala1, and H-J. Sung1 Vanderbilt University, Nashville, TN

1

8:00AM-9:30am Platform Sessions Sat-1

2014 | OCTOBER 25 | Saturday

8:30AM

Syndesomes: A Novel Therapy For Peripheral Ischemia S. Das1, A. Monteforte1, G. Singh1, M. Martinez1, A. Dunn1, and A. Baker1 1

University of Texas, Austin, Austin, TX

8:45AM

A Fluid Shear Stress Threshold Regulates Angiogenic Sprouting P. Galie1, P. Janmey1, and C. Chen2 1

University of Pennsylvania, Philadelphia, PA, 2Boston University, Boston, MA

Track: Orthopaedic and Rehabilitation Engineering, Tissue Engineering OP-Sat-1-10 - Room 007D

Musculoskeletal Tissue Engineering Chairs: Clark Hung, Warren Grayson 8:00AM

9:00AM

Evaluation of Endothelial Progenitor Cells for Microvessel Tissue Engineering

Chondroinductive Biomaterials for Cartilage Tissue Engineering M. Detamore1 1

E. Brown Peters1, N. Christoforou1,2, K. Leong1, G. Truskey1, and J. West1 1

Duke University, Durham, NC, Khalifa University, Abu Dhabi, United Arab Emirates 2

9:15AM

Physical Signals That Promote Vascularization of Capillary-Scale Channels N. Boland1, G. Covarrubias1, and J. Tien1 1

Young Innovator Session I Shrink Wrapping Cells in a Defined Extracellular Matrix to Modulate the Chemo-Mechanical Microenvironment R. Palchesko1, J. Szymanski1, A. Sahu1, and A. Feinberg1I Carnegie Mellon University, Pittsburgh, PA

8:15AM

Efficiency of Protease-activatable Virus Nanonodes Tuned Through Incorporation of Wild-type Capsid Subunits M. Ho1, J. Judd1, B. Kuypers1, M. Yamagami1, F. Wong1, and J. Suh1 Rice University, Houston, TX

8:30AM

Aqueous Two-Phase Printing of Tumor Spheroids For Drug Screening E. Atefi , S. Lemmo , D. Fyffe , G. Luker , and H. Tavana 1

1

University of Illinois at Urbana-Champaign, Urbana, IL

1

2

Dynamic Hydrostatic Pressure-induced Formation of Micropores in Mature Tissue-engineered Articular Cartilage T-A. Kelly1, S. Sirsi2, A. Nover1, C. Chen1, A. Ditzel1, P. Mountford2, S. Etezazian2, G. Ateshian1, M. Borden2, and C. Hung1 Columbia University, New York, NY, 2University of Colorado at Boulder, Boulder, CO

8:45AM

8:00AM

1

W. Grier1, L. Mozdzen1, S. Caliari1, D. Weisgerber1, M. Boppart1, and B. Harley1

1

Chairs: Cynthia Reinhart-King, Deborah Leckband

1

Spatial Control of MSC Fate Using 3D Multi-compartment Scaffolds for Engineering Orthopedic Interfaces

8:30AM

Track: Cellular and Molecular Bioengineering OP-Sat-1-9 - Room 007C

1

8:15AM

1

Boston University, Boston, MA

University of Kansas, Lawrence, KS

1

University of Akron, Akron, OH, 2University of Michigan, Ann Arbor, MI

Engineering Craniofacial Bone And Skeletal Muscle From AdiposeDerived Stem Cells W. Grayson1 1

Johns Hopkins University, Baltimore, MD

9:00AM

A Combined Experimental and Theoretical Approach to Designing Enzyme Degradable Hydrogels for Cartilage Tissue Engineering S. Skaalure1, S. Chu1, U. Akalp1, F. Vernerey1, A. Doostan1, and S. Bryant1 1

University of Colorado, Boulder, CO

9:15AM

The Use of Laminin-functionalized Hydrogels to Restore Pathological Nucleus Pulposus Cells of the Intervertebral Disc P. Hwang1, A. Francisco1, L. Jing1, W. Richardson1, R. Isaacs1, C. Brown1, J. Chen1, and L. Setton1 1

Duke University, Durham, NC

8:45AM

Quantitative Evaluation and Optimization of Co-drugging to Improve Anti-HIV Latency Therapy V. Wong1, L. Fong1, N. Adams1, Q. Xue1, S. Dey2, and K. Miller-Jensen1 1

Yale University, New Haven, CT, 2Hubrecht Institute, Utrecht, Netherlands

9:00AM

PAActivation of a Bacterial Mechanosensitive Channel in Mammalian Cells by Cytoskeletal Stress A. Liu , J. Heureaux , D. Chen , V. Murray , and C. Deng 1

1

1

1

1

1

University of Michigan, Ann Arbor, MI

9:15AM

Network Modeling Approach to Predict Myofibroblast Differentiation

Track: Nano to Micro Technologies, Device Technologies and Biomedical Robotics OP-Sat-1-11 - Room 008A

Cells Tissues and Organs on Chip I Chairs: Keith Neeves, Maribel Vazquez 8:00AM

Capillary Formation under Interstitial Flow in a Microfluidic Device for Liver Tissue Engineering R. Sudo1, Y. Abe1, S. Menjo1, and K. Tanishita2 1

A. Schroer1, L. Ryzhova1, and W. Merryman1 1

Vanderbilt University, Nashville, TN

Keio University, Yokohama, Japan, 2Waseda University, Tokyo, Japan

8:15AM

Simple Microfluidic Device for Automated, High-throughput Morphological Analysis of Stored Red Blood Cells N. Piety1, S. Gifford1, X. Yang1, and S. Shevkoplyas1 1

University of Houston, Houston, TX

BMES 2014

177

Platform Sessions

Sat-1

Saturday | OCTOBER 25 | 2014

Platform Sessions Sat-1 8:00AM-9:30aM

8:30AM

9:15AM

A. Smith1, J. Rosano1, C. Garson1, K. Bhatt1, B. Prabhakarpandian1, M. Aschner2, and K. Pant1

S. Fenn1, D. Wagner1, P. Saunders1, P. Charron1, D. Weiss1, and R. Oldinski1

Inflammation Mediated Modulation of Blood Brain Barrier In Vitro 1

An Alginate-Based Pulmonary Patch For Repairing Pleural Injuries 1

University of Vermont, Burlington, VT

CFD Research, Huntsville, AL, 2Albert Einstein College of Medicine, Bronx, NY



Track: Device Technologies and Biomedical Robotics, Translational Biomedical Engineering OP-Sat-1-13 - Room 201

8:45AM

A Human Blinking 'Eye-on-a-chip' J. Seo1 and D. Huh1 1

University of Pennsylvania, Philadelphia, PA

Biosensors I: Materials and Techniques

9:00AM

A Microfabricated Platform for Evaluating Prodrug Metabolism and Toxicity in a Hepatocyte-Cancer Model

Chairs: J-C Chiao, Jeff LaBelle

S. Bale1, R. Jindal1, G. Sridharan1, I. Golberg1, W. McCarty1, M. Hegde1, A. Bhushan1, L. Prodanov1, O. Usta1, and M. Yarmush1

Advancing Silicon Photonics for Clinical Applications

Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School and Shriners Burns Hospital, Boston, MA

1

8:00AM

D. Ratner1 University of Washington, Seattle, WA

1

9:15AM

8:30AM

M. Nourmohammadzadeh1, J. Mendoza-Elias1, Y. Xing1, J. Oberholzer1, and Y. Wong1

H. Culver1, C. Fauvarque Nuytten2, and N. Peppas1

A Microfluidic-Based Array for Large-Scale Ordering And HighResolution Imaging Of Islets 1

University of Illinois at Chicago, Chicago, IL

Macromolecularly Imprinted Polymers on the Surface of Nanoparticle Supports for Low-Cost Biosensors University of Texas at Austin, Austin, TX, 2Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

1

8:45AM

Track: Respiratory Bioengineering, Tissue Engineering OP-Sat-1-12 - Room 008B

Engineering Strategies for Lung Transplant & Regeneration Chairs: Daniel Weiss, Samir Ghadiali

Sat-1

1

B. Whitson

The Ohio State University, Columbus, OH

Colorado State University, Fort Collins, CO

9:00AM

Protease Detection Assay Based on Aggregation of Stimulus-Responsive Polypeptides Duke University, Durham, NC

9:15AM

Up-Regulation of Metabolites for Early Detection of Bacterial Pathogens in Human Biofluids H. Sismaet1, T. Webster1, and E. Goluch1

8:15AM

1

Design and Validation of a Clinical-Scale Biomimetic Whole-Lung Bioreactor J. Charest1, T. Okamoto1, A. Yasuda1, S. Gilpin1,2, D. Mathisen1, and H. Ott1,2 1

1

1

Ex-Vivo Lung Perfusion – A Bench to Bedside Platform for Pulmonary Investigation 1

W. Wilson1, K. Schoelfield1, J. Wydallis1, R. Feeny1, W. Tejio1, T. Kern1, S. Lantvit1, C. Henry1, S. Tobet1, M. Reynolds1, and T. Chen1

A. Ghoorchian1, A. Chilkoti1, and G. Lopez1

8:00AM Invited Platform Sessions

A High Density Electrochemical Imaging System for Understanding Cell-to-Cell Communication

Massachusetts General Hospital, Boston, MA, 2Harvard Medical School, Boston, MA

8:30AM

Enhanced Reseeding of Decellularized Rodent Lung Airway and Vasculature

Northeastern University, Boston, MA

Track: Drug Delivery, Cancer Technologies OP-Sat-1-14 - Room 103B

Cancer Drug Delivery I Chairs: Natalie Artzi, Hao Cheng

C. Stabler1, S. Lecht1, M. Barakat1, L. Caires2, A. Rylander1, R. Chiaverelli1, E. Schulman3, C. Marcinkiewicz1, and P. Lelkes1

8:00AM

Temple University, Philadelphia, PA, 2Federal University of Juiz de Fora, Juiz de Fora, Brazil, 3 Drexel University College of Medicine, Philadelphia, PA

M. Wu1, C-C. Chang1, and F. Yuan1

1

Role of Endocytosis in Electrotransfection of Tumor Cells 1

8:45AM

Mechanical Control of Airway Branching Morphogenesis V. Varner1, J. Gleghorn1, and C. Nelson1 Princeton University, Princeton, NJ

1

1

Engineered Cartilaginous Structures for Tracheal Tissue Replacement A. Dikina , H. Strobel , B. Lai , M. Rolle , and E. Alsberg 2

1

2

1

Case Western Reserve University, Cleveland, OH, 2Worcester Polytechnic Institute, Worcester, MA

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

178

BMES 2014

Mapping The CXCR4 Receptor On Breast Cancer Cells By AFM: A Tool For Engineering Targeted Drug Delivery Vehicles B. WANG1 and D. Auguste 1

9:00AM 1

Duke University, Durham, NC

8:15AM

The City College of New York, New York, NY

8:00AM-9:30am Platform Sessions Sat-1

2014 | OCTOBER 25 | Saturday

8:30AM

Systemic Delivery of Liposome-Anchored Cytokines Elicits Antitumor Immunity Without Lethal Toxicity Y. Zhang1,2,3 and D. Irvine1,2,3,4,5 Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, 2Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 3Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 4Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA, 5 Howard Hughes Medical Institute, Chevy Chase, MD 1

8:45AM

Core/Shell Systems for Improved Control of the Externally Triggered Release of Chemotherapeutics J. Peters1, N. Lizana1, I. Verma1, and N. Peppas1 1

The University of Texas at Austin, Austin, TX

Global Health I Chairs: Sergey Shevkoplyas, Leo Wan 8:00AM

A Low-cost, Paper-based Assay for Diagnosis of Sickle Cell Disease in Resource-limited Settings N. Piety1, X. Yang1, B. Dinu2, A. George2, and S. Shevkoplyas1 1

University of Houston, Houston, TX, 2Baylor College of Medicine, Houston, TX

8:30AM

9:00AM

A Long Circulating PVX-Based Nanoparticle for Enhanced Tumor Homing and Therapeutic Payload Delivery K. Lee1, S. Shukla1, K. Weber Bonk1, R. Keri1, and N. Steinmetz1 1

Track: New Frontiers and Special Topics, Device Technologies and Biomedical Robotics OP-Sat-1-16 - Room 202B

Case Western Reserve University, Cleveland, OH

GlucoSense: Design of a Low Cost Diabetes Glucometer System K. Gainey1, T. Ovington1, J. DesJardins1, and D. Dean1 1

Clemson University, Clemson, SC

8:45AM

Immunomodulatory Nanoparticles Ameliorate Disease in the Leishmania (Viannia) panamensis Mouse Model

Track: Neural Engineering, Device Technologies and Biomedical Robotics OP-Sat-1-15 - Room 202A

A. Siefert1, A. Ehrlich1, M. Corral Caridad2, K. Goldsmith-Pestana1, D. McMahon-Pratt1, and T. Fahmy1

Brain-computer Interfaces

Towards Development of an Autonomous Network of BacteriaBots: High-Throughput Spatiotemporal Characterization of Bacterial Quorum-Sensing Response

Chairs: Chris Passaglia, Erkin Seker

Yale University, New Haven, CT, 2Universidad Complutense de Madrid, Madrid, Spain

9:00AM

A. Sahari1, M. Traore1, A. Stevens1, B. Scharf1, and B. Behkam1

8:00AM

Role of Interleukin 1β Converting Enzyme on Recording Performance and the Reactive Tissue Response Around Chronic Neural Electrode T. Kozai1, X. Li1, L. Bodily1, E. Caparosa1, D. Carlisle1, R. Friedlander1, and X. Cui1 1

1

University of Pittsburgh, Pittsburgh, PA

1

Virginia Tech, Blacksburg, VA

9:15AM

Increasing Access to HIV Medication in Developing Countries: An Operational, Feasibility Study in Zambia A. Dahinten1, J. Ekuta1, and R. Malkin1

8:15AM

1

Duke University, Durham, NC

Understanding the Immune Response to Intracortical Microelectrodes J. Hermann1,2, M. Ravikumar, PhD1,2, J. Jiang1,3, J. Nguyen1,2, S. Sunil1, C. Wong1, A. Soffer1, V. Srivastava1, D. Taylor, PhD2,3, and J. Capadona, PhD1,2 Case Western Reserve University, Cleveland, OH, 2Louis Stokes Cleveland VA Medical Center, Cleveland, OH, 3Cleveland Clinic Lerner Research Institute, Cleveland, OH

Track: Biomedical Imaging and Optics OP-Sat-1-17 - Room 203A

8:30AM

Ultrasound Imaging

1

The Spatial Distribution of FBR Biomarkers Correlates with Recording Performance in Rats N. Nolta , M. Christensen , and P. Tresco 1

1

1

1

University of Utah, Salt Lake City, UT

8:45AM

Modeling Mechanics of Flexible Neural Probes Coated in an Ultra-fast Degrading Polymer for Optimizing Probe Design S. Singh1, M-C. Lo1, V. Damodaran2, H. Kaplan2, J. Kohn2, J. Zahn1, and D. Shreiber1 1

Rutgers University, Piscataway, NJ, 2New Jersey Center for Biomaterials, Piscataway, NJ

9:00AM

Flexible Neural Micoprobes Coated with a Fast Degrading Polymer as an Aid to Tissue Insertion M-C. Lo1, S. Singh1, V. B. Damodaran1, S. Wang1, H. M. Kaplan1, K. Coffey 1, D. Barker 1, J. D. Zahn1, D. I. Shreiber1, and J. Kohn1 1

Rutgers, the State University of New Jersey, Piscataway, NJ

9:15AM

Extracellular Matrix Coatings for CNS Neural Recording Arrays R. Oakes1, M. Polei1, J. Skousen1, and P. Tresco1 1

University of Utah, Salt Lake City, UT

Platform Sessions

Sat-1

Chairs: Baohong Yuan, Paul Carson 8:00AM

Development and Application of Ultrasound Techniques for Investigating Pathogenesis in Experimental Abdominal Aortic Aneurysms E. Phillips1, A. Yrineo1, H. Schroeder1, F. Damen1, A. Bogucki1, S. Jubaer1, A. Jackson1, R. Foley1, N. Blaize1, J-X. Cheng1, and C. Goergen1 1

Purdue University, West Lafayette, IN

8:15AM

RSNA QIBA Ultrasound Shear Wave Speed: Sources of Variability in Phantoms, Simulations and Humans P. Carson1, A. Milkowski2, T. Hall3, B. Garra4, K. Nightingale5, M. Palmeri5, A. Samir6, S. Chen7, T. Lynch8, N. Rouze5, M. Dhyani6, and D. Sullivan5 Univ. of Michigan, Ann Arbor, MI, 2Siemens Ultrasound, Issaquah, WA, 3Univ. of Wisconsin, Madison, WI, 4Veterans Health System, Hyattsville, MD, 5Duke Univ., Durham, NC, 6Mass. Gen'l Hospital, Boston, MA, 7Mayo Clinic, Rochester, MN, 8CIRS, Inc., Norfolk, VA

1

8:30AM

Ultrasound and Photoacoustic Imaging of Anatomical and Functional Indicators of Lymph Node Metastasis G. Luke1 and S. Emelianov1 1

The University of Texas at Austin, Austin, TX

BMES 2014

179

Saturday | OCTOBER 25 | 2014

Platform Sessions Sat-1 8:00AM-9:30aM

8:45AM

Formulation and In Vitro Characterization of Targeted Lipid-Pluronic Nanobubbles P. Kota1, C. Hernandez1, H. Wu1, and A. Exner1 1

Case Western Reserve University, Cleveland, OH

9:00AM

Skeletal Imaging and Assessment Using Hand-Held Focal Quantitative Ultrasound Technology J. Muir1, L. Lin1, J. Cheng1, and Y-X. Qin1 1

Stony Brook University, Stony Brook, NY

9:15AM

Bipolar Nanosecond Electric Pulses Display Reduced Efficacy Due to Acoustic Interference C. Roth1, R. Barnes2, S. Maswadi2, B. Ibey3, H. Beier3, and R. Glickman1 UTHSCSA, San Antonio, TX, 2UTSA, San Antonio, TX, 3Air Force Research Laboratories, San Antonio, TX

1

Track: Cancer Technologies, Nano to Micro Technologies OP-Sat-1-19 - Room 103A

Nanotechnologies for Cancer I Chairs: Carlos Rinaldi, Craig Duvall 8:00AM

Resources For Preclinical Characterization Of Nanomaterials For Cancer Diagnosis, Imaging & Therapy N. Panaro1, S. Stern1, A. Patri1, and S. McNeil1 1

Leidos Biomedical Research, Frederick, MD

8:15AM

In Vivo Targeting of Tumor Associated Macrophages Using Mannosylated Endosomal-Escape Nanoparticles R. Ortega1, W. Barham1, I. McFadden1, O. Tikhomirov1, K. Sharman1, F. Yull1, and T. Giorgio1

Track: Biomedical Imaging and Optics OP-Sat-1-18 - Room 203B

Optical Imaging and Microscopy I Chairs: Bernard Choi, Ken Tichauer 8:00AM

Near Infrared Fluorescent Neural Progenitor Cells to Track Differentiation and Tissue Innervation A. Mohs1,2, S. Raghavan1,2, R. Gilmont2, S. Somara2, F. Marini2, and K. Bitar1,2

Targeting Nanotechnology to Invasive Brain Tumors P. Peiris1, A. Abramowski1, L. Bauer1, R. Toy1, E. Doolittle1, S. Rao1, S. Shah1, K. Ghaghada2, S. Brady-Kalnay1, J. Basilion1, M. Griswold1, and E. Karathanasis1 Case Western Reserve University, Cleveland, OH, 2Texas Children's Hospital, Houston, TX

1

8:45AM

A Novel Triple Negative Breast Cancer Theranostic Target for Nanomedicine P. Guo1 and D. Auguste2

8:15AM

9:00AM

Boston Children's Hospital, Boston, MA, 2City College of New York, New York, NY

1

Imaging Three-Dimensional Nanoscale Morphometry of Type I Collagen Gels Using Focused Ion Beam Scanning Electron Microscopy

In Vivo Targeting of Adoptively Transferred T-cells with Nanoparticles for Cancer Immunotherapy

S. Reese1, N. Farhang1, and J. Weiss1

Y. Zheng1,2 and D. Irvine1,2,3,4

1

Sat-1

8:30AM

Wake Forest - Virginia Tech School of Biomedical Engineering and Sciences, WinstonSalem, NC, 2Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC

1

Platform Sessions

Vanderbilt University, Nashville, TN

1

University of Utah, Salt Lake City, UT

8:30AM

Light-sheet Single-Molecule Super-resolution Imaging of Tissues Y. Hu1, Z. Katz1, B. Lillemeier1, and H. Cang1 1

Salk Institute, La Jolla, CA

8:45AM

Intracellular Three-Dimensional Single-Particle Tracking with Multiplexed Two-Photon Excitation E. Perillo1, Y-L. Liu1, C. Liu1, H-C. Yeh1, and A. Dunn1 1

The University of Texas Austin, Austin, TX

9:00AM

Large Scale, High Resolution Imaging with a Simple and Robust Superresolution Light Sheet Microscopy P. Fei1 1

UCLA, Los Angeles, CA

9:15AM

Ultra-Wide Field-Of-View Gigapixel Fluorescent Imaging System Using A Modified Flatbed Scanner Z. Göröcs1, Y. Ling1, M. Yu1, D. Karahalios1, K. Mogharabi1, K. Lu1, Q. Wei1, and A. Ozcan1,2 University of California, Los Angeles, Los Angeles, CA, 2California NanoSystems Institute, Los Angeles, CA

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

180

BMES 2014

Massachusetts Institute of Technology, Cambridge, MA, 2Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, 3Ragon Institute of Massachusetts General Hospital, MIT and Harvard University, Cambridge, MA, 4Howard Hughes Medical Institute, Chevy Chase, MD 1

9:15AM

In Vivo Multiplex Photoacoustic Molecular Imaging for Optimization of Nanoparticle Targeting and Kinetics C. Bayer1, G. Luke1, and S. Emelianov1 The University of Texas at Austin, Austin, TX

1

8:00AM-9:30am Platform Sessions Sat-1

2014 | OCTOBER 25 | Saturday

Track: Biomedical Engineering Education (BME) OP-Sat-1-20 - Room 204A

SPECIAL SESSION

Novel Laboratory Modules

Ballroom A, Convention Center

Chairs: Ann Saterbak, Chris Geiger 8:00AM

Teaching Sequential Design of Experiments and Biomedical Process Optimization J. Audet1 1

University of Toronto, Toronto, ON, Canada

8:15AM

"Building Blocks" for Inventing Instruments in the Classroom D. Hill1, L. Anderson1, C. Hill1, and W. Grover1 1

University of California, Riverside, Riverside, CA

8:30AM

Receiving Feedback from Instructor and Peers Increases the Quality of Written Reports in a Biomedical Instrumentation Laboratory Course R. Ramos1 1

Rice University, Houston, TX

8:45AM

Integrating 3D Additive Manufacturing Technologies into a Tissue Engineering Lab Course A. Feinberg1 1

Carnegie Mellon University, Pittsburgh, PA

9:00AM

A Two-Dimensional Motion Analysis Laboratory for Introductory Courses in Biomedical Engineering C. Henak1 and S. Archer1 1

Cornell University, Ithaca, NY

9:15AM

Cloud Experimentation And Biotic Games As Novel Media For Bioengineering Education

8:00 AM – 9:30 AM

Advanced Biomanufacturing: Application Towards the Next Generation Therapies and Diagnostics Advanced Biomanufacturing is an emerging field in biomedical engineering. Unlike conventional bioprocessing technologies, advanced biomanufacturing builds on the groundbreaking discoveries such as 3D additive manufacturing, genome editing, cell reprogramming and transdifferentiation, systems and synthetic biology, stem cell biology, computational modeling, micro and nanofabrication, material genomes, biomaterials, tissue engineering and regenerative medicine. A group of leading scientists have worked together and recently launched a BMES special interest group (SIG) for advanced biomanufacturing (ABioM-SIG). The objective of the BMES SIG is to bring academic and industrial leaders together to promote the development of advanced biomanufacturing, foster collaborations among investigators in the field, and create a new mode of educating and training the next generation leaders and workforce in advanced biomanufacturing. This inaugural session is the BMES ABioM-SIG’s first official session to discuss opportunities and grand challenges in advanced biomanufacturing and to lay out a strategic plan to spur research, education, and industry growth and innovation in advanced biomanufacturing towards significant benefits to the patient population and the society at large. SPEAKERS: Microphysiological Tissue Platforms for Drug Testing in Human Health and Disease Gordana Vunjak-Novakovic, Professor, Department of Biomedical Engineering and Department of Medical Sciences, Columbia University,

I. Riedel-Kruse1, Z. Hossain1, A. Chung1, and N. Cira1 1

Stanford Bioengineering, Stanford, CA

Sat-1

Advanced Biomanufacturing: A New Wave of Biomedical Engineering Kaiming Ye, Professor and Department Chair, Department of Bioengneering, State University of New York, Binghamton (SUNY Binghamton) On the Threshold – Advanced Biomanufacturing and Clinical Challenges Peter Dillon, Professor and Department Chair, Department of Surgery, Penn State Milton S. Hershey Medical Center, Penn State College of Medicine Moderator: Athanassios Sambanis Panelists: Cheng Dong, Kam Leong, David Kaplan, Gang Bao, and Gilda Barabino

SPECIAL SESSION

BMES 2014

Platform Sessions

181

Saturday | OCTOBER 25 | 2014

Platform Sessions Sat-2 1:30PM-3:00PM

SATURDAY, October 25, 2014

1:45PM

1:30 PM - 3:00 PM PLATFORM SESSIONS – Sat - 2

R. Appavu1, C. Ding1, S. Stutz1, Y. Ding1, K. Cunningham1, J. Zhou1, and J. Rudra1

Track: Tissue Engineering, Stem Cell Engineering OP-Sat-2-1 - Room 001A

Adult Stem Cells in Tissue Engineering Chairs: Liping Tang, Michelle Dawson

2:00PM

M2e Conjugated Gold Nanoparticles Protect Against H1N1, H3N2 and H5N1 Influenza A Viruses W. Tao1, E. Tarbet2, and H. Gill1 1

Texas Tech Univeristy, Lubbock, TX, 2Utah State University, Logan, UT

2:15PM

Immunogenicity and Adjuvanticity of Biologically Derived Nanoparticles

TGF-β 1 Pretreatment Improves The Function Of Mesenchymal Stem Cells In The Wound Bed

Y. Wang1, Y. Huang1, L. Sun1, and M. Zhang1

1

Georgia Institute of Technology, Atlanta, GA

1:45PM

Photocrosslinkable, Biodegradable Hydrogels with Controlled Cell Adhesivity for Tunable siRNA Delivery to Encapsulated hMSCs M. Nguyen1, D. Schapira1, A. McMillan1, and E. Alsberg1 1

Case Western Reserve University, Cleveland, OH

2:00PM

Gelatin-based Injectable Microsphers for Encapsulating Mesenchymal Stem Cells B. Sung1, S. Shaffer 1, C. Kim1, and M-H. Kim1 1

1

Ohio State University, Columbus, OH

2:30PM

Membrane-interacting, Amphiphilic Gold Nanoparticles: Mechanisms for Bilayer-embedding and Applications in Peptide Vaccine Therapy P. Atukorale1, K. Moynihan1, D. Yun1, and D. Irvine1 1

Massachusetts Institute of Technology, Cambridge, MA

2:45PM

Pre-clinical Development of a Biomaterial-based Microparticle Vaccine for Type 1 Diabetes Attenuation J. Lewis1, M. Carstens1, N. Dolgova1, C-Q. Xia1, M. Clare-Salzler1, and B. Keselowsky1 1

University of Florida, Gainesville, FL

Kent State University, Kent, OH

2:15PM

Track: Biomaterials OP-Sat-2-3 - Room 006A

L. Velutheril Thomas1 and J. L.West1

Biomaterials Design I

A Novel ‘Differentiation Niche’ Promoting Stem Cell Differentiation to Smooth Muscle Lineage 1

Duke University, Durham, NC

Chairs: Abigail Koppes, Matt Kipper

2:30PM

Hypoxic Modulation of Mesenchymal Stem Cells Affects Macrophage Function for Ischemic Tissue Repair L. Ricles1, E. Chung1, N. Kopcho1, and L. Suggs1 1

Sat-2

Department of Pharmacology and Toxicology, Center for Addiction Research, University of Texas Medical Branch, Galveston, TX

1

1:30PM

D. Ghosh1, D. McGrail1, and M. Dawson1

Platform Sessions

Nanomaterials-based Vaccines for Cocaine Addiction

The University of Texas at Austin, Austin, TX

1:30PM Invited

Biomaterials Design for Enhanced Vascularization and Healing 1 1

G. Vunjak-Novakovic

Columbia University, New York, NY

2:45PM

2:00PM

A. Nair 1, J. Shen1, C. Zhang2, R. Saxena2, J. Borrelli3, R. Tran4, J. Yang4, and L. Tang1

G. Chen1, X. Shi2, L. Guo2, K. Kent2, and S. Gong1,3

Tissue Regeneration Using Scaffold-mediated Autologous Progenitor Cell Responses In Vivo University of Texas at Arlington, Arlington, TX, 2University of Texas Southwestern Medical Center at Dallas, Dallas, TX, 3Texas Health Arlington Memorial Hospital, Arlington, TX, 4 Pennsylvania State University, University Park, PA 1

Periadventitial Application of Rapamycin-Loaded Nanoparticles Produces Sustained Inhibition of Vascular Restenosis Materials Science Program and Wisconsin Institute for Discovery, University of Wisconsin– Madison, Madison, WI, 2Department of Surgery, University of Wisconsin Hospital and Clinics, Madison, WI, 3Department of Biomedical Engineering, University of Wisconsin– Madison, Madison, WI

1

2:15PM

Track: Biomaterials, Cellular and Molecular Bioengineering OP-Sat-2-2 - Room 001B

Polysaccharide Mediated Pore Formation For 3D Myotube Formation M. Rich1, M. Lee1, N. Marshall2, J. Chen1, and H. Kong1 1

University of Illinois, Urbana, IL, 2Drake University, Des Moines, IA

2:30PM

Chairs: Jeffrey Capadona, Adam Ekenseair

Polycarbonates Built From the Polyhydroxyl Natural Products Quinic Acid and Glucose: Tuning the Thermal, Mechanical, and Surface Properties for Degradable Medical Plastics Applications

1:30PM

L. Link1, T. Gustafson1, A. Lonnecker1, J. Raymond1, K. Hearon1, C. Maher1, D. Maitland1, and K. Wooley1

Biomaterials for Immunoengineering I The Aggregate Structure of Self-Assembled Nanocarriers Specifies Their In Vivo Uptake By Antigen Presenting Cell Subsets E. Scott , A. de Titta , and J. Hubbell 1

1

2

2

Northwestern University, Evanston, IL, 2EPFL, Lausanne, Switzerland

1

Texas A&M University, College Station, TX

2:45PM

Rheological and Mechanical Characterization of Biocomposites Based on Chitosan with Potential Use as Bone Adhesives L. Pinzon1, F. Cedano1, F. Salcedo1, J. Casas1, C. Moreno1, J. Briceno1, and D. Tabima1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

182

BMES 2014

Universidad de los Andes, Bogota, Colombia

1:30PM-3:00PM Platform Sessions Sat-2

2014 | OCTOBER 25 | Saturday

2:00PM

Track: Biomechanics, Cardiovascular Engineering OP-Sat-2-4 - Room 006B

Aortic Biomechanics

Matrix Stiffening Contributes to Retinal Endothelial Inflammation Associated with Diabetic Retinopathy

Translation of AAA Rupture Risk Assessment: Wall Mechanics and Geometric Quantification

X. Yang1, H. Scott1, S. Ardekani1, and K. Ghosh1 1

S. Raut1, J. Shum2, and E. Finol3

Ocular Compliance in Mice S. Schwaner1, J. Sherwood2, E. Geisert3, D. Overby2, and C. Ethier1 Georgia Institute of Technology, Atlanta, GA, 2Imperial College London, London, United Kingdom, 3Emory University, Atlanta, GA

1

Role of Aneurysm on Biomechanics of Radially-Oriented Fibers in Human Ascending Thoracic Aorta A. Tsamis1, S. Pal2, J. Phillippi2, S. Pasta3, A. D’Amore2,3, T. Gleason2, D. Vorp 2, and S. Maiti2 3

University of California, Riverside, Riverside, CA

2:30PM

University of Texas at Austin, Austin, TX, Carnegie Mellon University, Pittsburgh, PA, University of Texas at San Antonio, San Antonio, TX 2

1:45PM

1

Virginia Tech - Wake Forest University Center for Injury Biomechanics, Blacksburg, VA

2:15PM

1:30PM

3

V. Alphonse1, A. Kemper1, and S. Duma1 1

Chairs: Craig Goergen, Zhijie Wang

1

Effect of Orbital Geometry on Eye Response to Survivable Primary Blast Overpressure

Carnegie Mellon University, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, Fondazione Ri.MED and DICGM University of Palermo, Palermo, Italy

2:45PM

Primary Blast Influences Incidence and Severity of Ocular Injury in a Porcine Eye Model D. Sherwood1, B. Lund2, R. Glickman3, W. Sponsel1,4, W. Gray1, R. Watson1, K. Thoe4, and M. Reilly1

2:00PM

University of Texas San Antonio, San Antonio, TX, 2U.S. Army Institute of Surgical Research, Ft Sam Houston, TX, 3University of Texas Health Science Center at San Antonio, San Antonio, TX, 4WESMDPA, San Antonio, TX

1

The Role of Heparanase in Aneurysm Development and Cardiac Function V. Le1 and A. Baker1 1

University of Texas at Austin, Austin, TX

2:15PM

A Biochemomechanics Model of Stress-Mediated Vascular Adaptation in Normal Physiological Conditions H. Getachew1 and S. Baek1 1

Microtechnologies for Cancer I

Michigan State University, East Lansing, MI

Chairs: Rafael Davalos, Samir Iqbal

2:30PM

Viscoelastic Characterization of Damage Progress in Porcine Aortic Tissues In Vitro

1:30PM

M. Sharma1, A. Valdevit1, C. Perlman1, Y. Wu1, A. Kharge1, and D. Shahmirzadi1 1

Track: Cancer Technologies, Nano to Micro Technologies OP-Sat-2-6 - Room 006D

Stevens Institute of Technology, Hoboken, NJ

Dielectrophoretic Isolation and Detection of Cancer Related Circulating Cell Free DNA Biomarkers from Blood and Plasma M. Heller1 University of California San Diego, La Jolla, CA

1

2:45PM

An Alternative Method to Measure the Diameter of Abdominal Aortic Aneurysms Using Maximally Inscribed Spheres

1:45PM

H. Gharahi1, B. Zambrano1, C. Lim1, J. Choi1, W. Lee2, and S. Baek1

A. Sarioglu1, N. Aceto1, N. Kojic1, M. Donaldson1, M. Zeinali1, B. Hamza1, A. Engstrom1, H. Zhu1, T. Sundaresan1, D. Miyamoto1, X. Luo1, A. Bardia1, B. Wittner1, S. Ramaswamy1, T. Shioda1, D. Ting1, S. Stott1, R. Kapur1, S. Maheswaran1, D. Haber1, and M. Toner1

Michigan State University, East Lansing, MI, Seoul National University Hospital, Seoul, Korea, Republic of

1

2

Circulating Tumor Cell Cluster-Chip Platform Sessions

Sat-2

Harvard Medical School, Charlestown, MA

1

Track: Biomechanics OP-Sat-2-5 - Room 006C

2:00PM

Ocular Biomechanics

X. Jiang1, A. Khankhel1, E. Reategui1, M. Zeinali1, M. Phillips1, F. Fachin1, A. Hoang1, A. Jensen1, L. Sequist2, S. Maheswaran2, D. Haber2, S. Stott1, and M. Toner1

Platelet-Targeted Microfluidic Isolation of Circulating Tumor Cells

Chairs: Ross Ethier, Matthew Reilly

Massachusetts General Hospital and Harvard Medical School, Boston, MA, 2Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA

1

1:30PM

Effect Of Cell Stiffness On Transcellular And Paracellular Pore Formation In Schlemm's Canal Cells

2:15PM

M. Johnson1, S. Braakman2, R. Pedrigi2, A. Vahabikashi1, J. Sherwood2, R. Vargas-Pinto1, R. Gupta2, K. Perkumas3, W. Stamer3, C. Ethier4, and D. Overby2 1 3

Northwestern University, Evanston, IL, 2Imperial College London, London, United Kingdom, Duke University, Durham, NC, 4Georgia Tech, Atlanta, GA

1:45PM

The Role of Ocular Lens-Specific Proteins In Determining Lens Optical and Mechanical Properties M. Reilly , S. Kumar , B. Rapp , N. Ravi , , P. Hamilton , M. Leroux , A. Shiels , and B. Marchand1 1

1

2

3 4

4

1

University of Texas at San Antonio, San Antonio, TX, Indiana University Health, Indianapolis, IN, 3Washington University in St. Louis, St. Louis, MO, 4Department of Veterans Affairs, St. Louis, MO

1

2

1

Non-Fixative Preservative Solution for Stabilizing Circulating Tumor Cells in Whole Blood R. Sandlin1, K. Wong1, T. Carey1, A. Khankhel1, A. Shank1, J. Walsh1, D. Irimia1, S. Maheswaran1, D. Haber1, S. Stott1, and M. Toner1 Massachusetts General Hospital, Harvard Medical School, Charlestown, MA

1

2:30PM

Shear-responsive Nanocoating for Single Circulating Tumor Cell DNA Analysis E. Reátegui1,2, N. Aceto2,3, J. Sullivan2,3, A. Jensen1, E. Lim4, M. Zeinali1, J. Martel1,2, A. Aranyosi1, W. Li4, A. Bardia3, L. Sequist3, D. Haber3,5, S. Maheswaran3, P. Hammond4, M. Toner1,2, and S. Stott1,3 Center for Engineering in Medicine, Massachusetts General Hospital, Charlestown, MA, Harvard Medical School, Boston, MA, 3Massachusetts General Hospital Cancer Center, Charlestown, MA, 4Massachusetts Institute of Technology, Cambridge, MA, 5Howard Hughes Medical Institute, Chevy Chase, MD

1 2

BMES 2014

183

Saturday | OCTOBER 25 | 2014

Platform Sessions Sat-2 1:30PM-3:00PM

2:45PM

Detecting DNA Damage Electrically With Solid-State Nanopores M. Marshall1, J. Ruzicka1, E. Taylor1, and A. Hall2 University of North Carolina Greensboro, Greensboro, NC, 2Wake Forest University School of Medicine, Winston-Salem, NC

1

2:15PM

The Role of Valve Interstitial Cell Structure on Initiation and Progression of Aortic Valve Disease A. Razavi1, J. Carradini1, and K. Balachandran1 1

University of Arkansas, Fayetteville, AR

2:30PM

Track: Stem Cell Engineering, Tissue Engineering OP-Sat-2-7 - Room 007A

Directing Stem Cell Differentiation Chairs: Steven George, Randolph Ashton 1:30PM Invited

Membrane Capacitance Indicates Neural Stem Cell Fate Via Specific Cell Surface Molecules J. Nourse1, S. Ahmed1, J. Arulmoli1, B. Povieng1, L. McDonnell1, C. Soemardy1, and L. Flanagan1 1

University of California Irvine, Irvine, CA

1:45PM

1

University of New Mexico, Albuquerque, NM

2:45PM

Effect of Boundary Stiffness on Maintenance of Myofibroblast Phenotype M. Kural1 and K. Billiar1 1

Worcester Polytechnic Institute, Worcester, MA

Track: Cellular and Molecular Bioengineering OP-Sat-2-9 - Room 007C

Young Innovator Session II

P. Mistriotis1, M. Liang1, L. Karacosta2, and S. Andreadis1

Chairs: Cynthia Reinhart-King, Deborah Leckband

University at Buffalo, Amherst, NY, 2University at Buffalo, Buffalo, NY

2:00PM

Oxygenation Augments Myogenic Differentiation of Mesenchymal Stem Cells under Ischemic Conditions Y. Xu1, M. Fu1, Z. Li1, X. Li1, Z. Fan1, P. Anderson1, Z. Liu1, and J. Guan1 1

The Ohio State University, Columbus, OH

2:15PM

Direct Conversion of Skin Stem Cells into Functional Neural Crest Fate V. Bajpai1 and S. Andreadis1 1

University at Buffalo, Amherst, NY

2:30PM

Directed In Vitro Myogenesis of Human Embryonic Stem Cells and Their In Vivo Delivery Using Biomimetic Materials S. Varghese1, H. Kabra2, Y. Hwang2, and M. Kar2 1

Sat-2

E. Hedberg-Dirk1 and M. Rush1

Nanog Restores the Lost Myogenic Capacity of Senescent Stem Cells 1

Platform Sessions

Novel Mechanism of Directing Osteoblastic-like Differentiation in Valvular Interstitial Cells

UC San Diego, La Jolla, CA, 2UCSD, La Jolla, CA

1:30PM

The Relative Role of Soluble Guanylyl Cylase Dependent and Independent Pathways in Nitric Oxide Inhibition of Platelet Aggregation Under Flow J. Sylman1, S. Lantvit2, M. Reynolds2, and K. Neeves1 1

Colorado School of Mines, Golden, CO, 2Colorado State University, Ft Collins, CO

1:42PM

Depolarization of Resting Membrane Potential Stimulates Neonatal Cardiomyocyte Proliferation In Vitro J-Y. Lan1, C. Williams1, M. Levin1, and L. Black III1,2 1

Tufts University, Medford, MA, 2Tufts University School of Medicine, Boston, MA

1:54PM

Membranes Promote Endothelial Differentiation of Adipose-Derived Stem Cells and Perivascular Interactions A. Mazzocchi1, J-P. DesOrmeaux2, A. Man1, and T. Gaborski1 1

Rochester Institute of Technology, Rochester, NY, 2SiMPore Inc., West Henrietta, NY

2:06PM

Track: Cardiovascular Engineering OP-Sat-2-8 - Room 007B

Heart Valves and Stents I Chairs: Michael Sacks, Craig Simmons 1:30PM

Simulation of Heart Valve Biomaterial Fatigue M. Sacks1 1

University of Texas at Austin, Austin, TX

1:45PM

A Comparative Analysis of Valvular Cell Calcification from Coronary or Non-coronary Aortic Valve Cusps S. Masjedi1, R. Acharya1, and Z. Ferdous1 1

University of Tennessee, Knoxville, TN

2:00PM

Pharmacological Targeting of Cadherin-11 Prevents Valvular Calcific Nodule Formation M. Bowler1 and W. Merryman1 1

Vanderbilt University, Nashville, TN

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

184

BMES 2014

Microscale Bio-adhesive Hydrogel Arrays for Cell Engineering Applications R. Patel1, A. Purwada1, A. Gaharwar2, and A. Singh1 1

Cornell University, Ithaca, NY, 2Texas A&M University, College Station, TX

2:18PM

Nuclear Deformability Constitutes a Rate-limiting Step During Cell Migration in 3-D Environments P. Davidson1, C. Denais1, M. Bakshi1, and J. Lammerding1 1

Cornell University, Ithaca, NY

2:30PM

Electrospun Polymers for Reprogramming Human Cells T. Cordie1, T. Harkness1, X. Jing1, H-Y. Mi1, L-S. Turng1, and K. Saha1 1

University of Wisconsin-Madison, Madison, WI

2:42PM

Endometriotic Epithelial Cell Response to Macrophage-Secreted Factors is Dependent on Extracellular Matrix Context K. Pollock1, T. Jaraczewski1, M. Carroll1, D. Lebovic2, and P. Kreeger1 University of Wisconsin-Madison, Madison, WI, 2University of Wisconsin School of Medicine and Public Health, Madison, WI

1

1:30PM-3:00PM Platform Sessions Sat-2

2014 | OCTOBER 25 | Saturday

2:00PM

A Microfluidic Vascular Injury Model Using Heat-induced Endothelial Cell Activation

Track: Drug Delivery OP-Sat-2-10 - Room 007D

J. Sylman1, S. Retterer2, K. Rana1, and K. Neeves1,3

Targeted Drug Delivery I

1 3

Chairs: Yun Wu, Michael Davis

Colorado School of Mines, Golden, CO, 2Oak Ridge National Laboratory, Oak Ridge, TN, University of Colorado Denver, Denver, CO

2:15PM

1:30PM

A Universal Protein Tag for Delivery of SiRNA - Aptamer Chimeras

Digital Microfluidic Immunocytochemistry in Single Cells (DISC) for Analysis of Cell Signaling

H. Liu1 and X. Gao2

A. H. C. Ng1, M. D. Chamberlain1, and A. R. Wheeler1

1

Georgia Regents University, Evans, GA, 2University of Washington, Seattle, WA

1

University of Toronto, Toronto, ON, Canada

1:45PM

2:30PM

N. Nosoudi1, A. Sinha1, P. Nahar1, and N. Vyavahare1

Y. Gu1, Q. Sun1, W. Zhang1, J. Zilberberg2, A. Valdevit1, and W. Lee1

Local Inhibition of MMPs in Abdominal Aortic Aneurysm Rat Model Using Anti-elastin Decorated Nanoparticles Loaded with Batimastat 1

Stevens Institute of Technology, Hoboken, NJ, 2Hackensack University Medical Center, Hackensack, NJ

Clemson University, Clemson, SC

1

2:00PM

Membrane-Embedding Nanoparticles as Cytosolic Drug Delivery Vehicles for Infectious Diseases. Y-S. Yang1, A. Bekdemir 2, F. Stellacci2, and D. Irvine3 Massachusetts Institute of Technology, Cambridge, MA, 2École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 3Massachusetts Institute of Technology and Howard Hughes Medical Institute, Cambridge, MA

1

2:15PM

Selective Enhancement of Macropinocytosis For The Delivery Of a Mitochondriotoxic Peptide To Non-Small Cell Lung Cancer (NSCLC) R. Iglesias1 and P. Koria1 1

Microfluidic Reconstruction of 3D Osteocyte Network and Mechanotransduction Function

University of South Florida, Tampa, FL

2:45PM

A Microfluidic Platform For Dopaminergic Neuron Growth And In-Line Dopamine Uptake Measurements Y. Yu1, M. Shamsi1, D. Krastev1, and A. Wheeler1 1

University of Toronto, Toronto, ON, Canada

Track: Respiratory Bioengineering, New Frontiers and Special Topics OP-Sat-2-12 - Room 008B

Translational Respiratory Engineering

2:30PM

Targeting of Atheroprone Vasculature for Diagnostic Imaging and Prophylactic Drug Delivery

Chairs: Joseph Bull, William Federspiel

L. Hofmeister1, S. Lee1, W. Chen1, T. Giorgio1, D. Harrison1, and H-J. Sung1

Respiratory Devices – “Bench to Bedside”

1

Vanderbilt University, Nashville, TN

1:30PM Invited P. DeComo1

2:45PM

1

Soluble Epoxide Hydrolase Inhibitor for Nerve Regeneration: Delivery by a Synthetic Nerve Conduit. C. Terry1, J. Agarwal1, Y. He1, S. Heilshorn2, C. Morisseau3, and J. Shea1 University of Utah, Salt Lake City, UT, Stanford University, Stanford, CA, UC Davis, Davis, CA

1

2

3

ALung Technologies, Inc., Pittsburgh, PA

1:45PM

An Acoustic Method for Detecting Air Flow in Artificial Airways K. Yang1, A. Muelenaer2,3, A. Wicks4, and T. Ruscher4 Burton Center for Arts and Technology- Center for Engineering, Salem, VA, 2Carilion Clinic Children's Hospital, Roanoke, VA, 3Virginia Tech Carilion School of Medicine, Roanoke, VA, 4 Virginia Tech, Blacksburg, VA 11

Track: Nano to Micro Technologies, Device Technologies and Biomedical Robotics OP-Sat-2-11 - Room 008A

2:00PM

Cells Tissues and Organs on Chip II

1

Chairs: Shannon Weigum, Joseph Kinsella 1:30PM

Inflammatory Cell Trafficking Dynamics Across the Blood-Brain Barrier on a Novel Fluidic Platform C. Palmiotti1, R. Beard2, A. Conway1, F. Sinatra1, S. Yuan2, S. Sundaram1, and A. Achyuta3 Draper Laboratory, Tampa, FL, 2Dept. of Molecular Pharmacology & Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, 3Draper Laboratory, Cambridge, MA 1

S. Madhani1, B. Frankowski1, C. Bermudez1, and W. Federspiel1 University of Pittsburgh, Pittsburgh, PA

2:15PM

Microtopographies LIMIT Bacterial Biofilm Accumulation: A Novel Approach to Decreasing Ventilator-Associated Pneumonia CASES E. Mann1, R. May1, R. Mettetal1, A. Brennan2, and S. Reddy1 Sharklet Technologies, Inc, Aurora, CO, 2University of Florida, Gainesville, FL

2:30PM

Modeling A Novel Design For A Total Artificial Lung With Enhanced Flow Mixing P. Fernando1, H. Cheriyan1, J. Bull1, and R. Bartlett1 1

1:45PM

Sat-2

In Vitro Performance Of A Compact Integrated Blood PumpOxygenator For Ambulatory Respiratory Assist

1

University of Michigan, Ann Arbor, MI

Body-on-a-Chip Simulation with Gastrointestinal Tract and Liver Tissues Suggests that Ingested Nanonanoparticles Have the Potential to Cause Liver Injury

2:45PM

M. Esch , G. Mahler , T. Stokol , and M. Shuler

B. Smith1, L. Lundblad1, J. Satalin2, M. Kollisch-Singule2, B. Emr2, K. Snyder2, L. Gatto3, P. Andrews4, N. Habashi4, G. Nieman2, and J. Bates1

1

1

2

1

1

Cornell University, Ithaca, NY, 2Binghamton University, Binghamton, NY

Personalized Predictions of Recruitment, Derecruitment, and Tissue Distention in the Injured Lung 1 3

University of Vermont, Burlington, VT, 2SUNY Upstate Medical University, Syracuse, NY, SUNY Cortland, Cortland, NY, 4University of Maryland, Baltimore, MD

BMES 2014

Platform Sessions

185

Saturday | OCTOBER 25 | 2014

Platform Sessions Sat-2 1:30PM-3:00PM

2:00PM

Track: Device Technologies and Biomedical Robotics, Translational Biomedical Engineering OP-Sat-2-13 - Room 201

Biosensors II: Applications Chairs: Sihong Wang, Lissett Bickford 1:30PM

Multimarker Diabetes Management Device J. La Belle1,2 and C. Cook2 1

Arizona State University, Tempe, AZ, Mayo Clinic College of Medicine, Scottsdale, AZ

L. Plucinski1, A. Hsiao1, M. Gartia1, W. Arnold1, A. Ameen1, A. Das1, and G. Liu1 University of Illinois at Urbana-Champaign, Urbana, IL

2:00PM

Rapid And No-wash Detection Of Avianin Fluenza A Virus From Clinical Swab Samples C. Cheng1, H. Cui1, Q. Yuan1, J. Wu1, and S. Eda1 The University of Tennessee, Knoxville, TN

1

Polyanionic Nanoscale Hydrogels for the Oral Delivery of Chemotherapeutics A. Puranik1, D. Spencer1, V. White1, L. Pao1, and N. Peppas1 1

The University of Texas at Austin, Austin, TX

Non-viral DNA Delivery to Human Adipose Mesenchymal Stem Cells for Glioblastoma Treatment A. Denduluri1, S. Tzeng1, K. Kozielski1, O. Wijesekera2, A. Mangraviti2, K. Chaichana2, H. Guerrero-Cazares 2, J. Green3, and A. Quinones-Hinojosa2 Dept. of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 2Dept. of Neurosurgery, Johns Hopkins University, Baltimore, MD, 3Dept. of Biomedical Engineering & Dept. of Neurosurgery, Johns Hopkins University, Baltimore, MD

1

2:45PM

Biological Response To Multiple Administrations Of Viral Nanoparticles Carriers: Implication For Long-Term Drug Delivery Applications 1

A Focused Surface Acoustic Wave Device for Rapid and Sensitive Detection of Listeria Monocytogenes Based on Recombinase Polymerase Amplification L. Ren1, F. Guo1, Y. Chen1, P. Li1, Y. Xie1, and T. Huang1 Penn state university, State College, PA

2:30PM

Multi-Modal System For Monitoring Cellular Behavior L. Wong1, C. Manjunath1, M. Perez1, C. Horner1, M. Maldonado1, and J. Nam1 University of California, Riverside, Riverside, CA

Case Western Reserve University, Cleveland, OH

Track: Neural Engineering OP-Sat-2-15 - Room 202A

Glial Cell Engineering / Neural Progenitor Cell and Tissue Engineering Chairs: Deanna Thompson, Ryan Gilbert 1:30PM

2:45PM

Multi-Electrode Sensing for Signal-to-Noise Ratio Enhancement of Impedance Cytometry S. Emaminejad1, S. Talebi1, R. Davis1, and M. Javanmard1 1

2:15PM

S. Shukla1, D. Dorand1, J. Myers1, J. Whitney1, A. Huang1, and N. Steinmetz1

2:15PM

1

Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD

1

2:30PM

Colorimetric Detection of Substrate Binding to Cytochrome P450 with Plasmonic Nano Lycurgus Cup Array

1

C. Zhang1, E. Nance1, P. Mastorakos1, J. Chisholm1, S. Berry1, J. Suk1, and J. Hanes1

2

1:45PM

1

Nanotechnology Strategies to Improve Therapeutic Relevancy of Cisplatin for Malignant Gliomas

Stanford University, Stanford, CA

Schwann Cells and Electrical Stimulation: Enhanced Migration and Neurotrophic Factors to Aid PNS Repair L. Zhang1, A. Koppes1, K. Kearns1, and D. Thompson1 1

Rensselaer Polytechnic Institute, Troy, NY

1:45PM Platform Sessions

Sat-2

Track: Drug Delivery, Cancer Technologies OP-Sat-2-14 - Room 103B

Cancer Drug Delivery II Chairs: Beata Chertok, Omolola Eniola-Adefeso 1:30PM

Hydrophobically Modified Glycol Chitosan Nanoparticles: Enzymatic Stability, pH Responsiveness, Biocompatibility and Uptake G. Suarato , A. Chin , and Y. Meng 1

1

2

1

Stony Brook University, Stony Brook, NY, 2Rensselaer Polytechnic Institute, Troy, NY

1:45PM

Unnatural Killer Cells: TRAIL-coated Leukocytes Kill Cancer Cells in a Spontaneous Metastasis Mouse Model of Prostate Cancer

Piezoelectric Fibrous Scaffolds for Schwann Cell Induced Spinal Cord Repair Y-S. Lee1, S. Damarju2, S. Wu2, M. Bunge1, and T. Arinzeh2 1

2:00PM

Aligned, Electrospun Fibers as Artificial Axons to Study Oligodendrocyte Myelination S. Lee1, S. Tuck2, M. Leach3, S. Chong1, J. Chan1, and J. Corey2,3 University of California at San Francisco, San Francisco, CA, 2VA Ann Arbor Healthcare Center, Ann Arbor, MI, 3The University of Michigan, Ann Arbor, MI

1

2:15PM

Three-Dimensional Microscaffolds for Enrichment and Transplantation of Human Pluripotent Stem Cell-Derived Neurons N. Francis1, N. Bennett1, A. Carlson1, A. Halikere1,2, Z. Pang2, and P. Moghe1 1

M. Mitchell1, E. Wayne1, C. Schaffer1, and M. King1 1

Cornell University, Ithaca, NY

University of Miami, Miami, FL, 2New jersey Institute of Technology, Newark, NJ

Rutgers University, Piscataway, NJ, 2Child Health Institute of New Jersey, New Brunswick, NJ

2:30PM

A Novel Injectable Hydrogel-Based Drug Delivery System for Local Delivery of T3 to Promote Myelination after Spinal Cord Injury R. Shultz 1 and Y. Zhong1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

186

BMES 2014

Drexel University, Philadelphia, PA

1:30PM-3:00PM Platform Sessions Sat-2

2:45PM

Engineering a White Matter Model of Traumatic Brain Injury B. Pfister1, A. Adams1, J. Zalk1, and H. Kim2 1

New Jersey Institute of Technology, Newark, NJ, 2Rutgers University, Newark, NJ

2014 | OCTOBER 25 | Saturday

1:45PM

Diagnostic Accuracy of Integrated Intravascular Ultrasound and Optical Coherence Tomography for the Detection and Characterization of Human Atherosclerotic Plaque T. Ma1, J. Li2, A. Correa1, D. Mohar2, P. Patel2, K. Shung1, Z. Chen2, and Q. Zhou1

Track: New Frontiers and Special Topics, Device Technologies and Biomedical Robotics OP-Sat-2-16 - Room 202B

Global Health II Chairs: Elain Fu, Anand Ramasubramanian 1:30PM

Colorimetric Detection of Azidothymidine Using an Alkyne-Modified Dextran Substrate G. Pratt1, A. Fan1, and C. Klapperich1 1

Boston University, Boston, MA

1:45PM

Conversion of a Laboratory-based Colorimetric Assay to a Field-use Paper-based Test for the Detection of Phenylketonuria in Newborns G. Thiessen1, K. De Los Reyes1, R. Monnat1, and E. Fu2 1

University of Washington, Seattle, WA, 2Oregon State University, Corvallis, OR

2:00PM

Quantitative Real-Time Recombinase Polymerase Amplification of HIV-1 DNA B. Rohrman1, Z. Crannell1, and R. Richards-Kortum1 1

Rice University, Houston, TX

2:15PM

Real-time Fluorescence Detection of Nucleic Acid Amplification on a Mobile Phone for TB Diagnosis

University of Southern California, Los Angeles, CA, 2University of California, Irvine, Irvine, CA

1

2:00PM

Multi-Modal Validation Framework of Mitral Valve Geometry and Biomechanical Models S. Grbic1, T. Easley2, T. Mansi1, D. Neumann1, E. Pierce2, M. Jensen2, C. Bloodworth2, A. Siefert2, J. Krebs1, D. Yuh3, A. Yoganathan2, and D. Comaniciu1 Siemens, Princeton, NJ, 2Georgia Tech, Atlanta, GA, 3Yale University School of Medicine, New Haven, CO

1

2:15PM

Rapid Throughput, Seamless Imaging of Human Hip Joint Tissue Across Length Scales to Elucidate Emergent Structure-Function Relationships D. Zeidler1, U. Knothe2, T. Garbowski1, G. Dellemann1, and M. Knothe Tate3 Carl Zeiss Microscopy, Oberkochen, Germany, 2Cleveland Clinic, Cleveland, OH, 3University of New South Wales, UNSW Sydney, Australia

1

2:30PM

Quantitative Measurement of Cerebrospinal Fluid Flow in Ventricular Shunts by Contrast-enhanced Ultrasound and Cross-correlation Based Microbubble Tracking R. Hartman1, S. Aglyamov1, D. Fox2, and S. Emelianov1 1

University of Texas at Austin, Austin, TX, 2St. David's NeuroTexas Institute, Austin, TX

2:45PM

Novel Dental Imaging System J. Johnson1, S. Gray1, L. Leonard1, and R. Weber2 1

UTSI, Tullahoma, TN, 2MDI, Arlington Heights, IL

A. Skandarajah1, B. Baker2, M. Kato-Maeda3, A. Cattamanchi3, and D. Fletcher1 University of California, Berkeley, Berkeley, CA, 2Lawrence Livermore National Laboratory, Livermore, CA, 3UCSF Medical School, San Francisco, CA

1

2:30PM

Fluorescence Detection of DNA Amplification in Porous Media for Point-of-Care Diagnostics C. Monahan1, J. Bishop1, and P. Yager1 1

University of Washington, Seattle, WA

2:45PM

A Fully Integrated Paper-Based Assay for the Extraction, Isothermal Amplification, and Detection of Pandemic (H1N1) Influenza A RNA N. Rodriguez1,2, A. Fan1, J. Linnes1, C. Chen1,2, and C. Klapperich1 Boston University, Boston, MA, 2Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA

1

Track: Biomedical Imaging and Optics OP-Sat-2-17 - Room 203A

Track: Biomedical Imaging and Optics OP-Sat-2-18 - Room 203B

Optical Imaging and Microscopy II Chairs: Javier Jo, Michael Fenn 1:30PM

Bioengineering Autobioluminescence for Biomedical Imaging: From Microbe to Man S. Ripp1, T. Xu2, D. Close2, and G. Sayler1 1

The University of Tennessee, Knoxville, TN, 2490 BioTech Inc., Knoxville, TN

1:45PM

Live-Cell Analysis of Fibroblast Phenotype on Electrospun Meshes using Surface Enhanced Raman Spectroscopy E. Kibrom1, N. Roki1, C. Bashur1, and M. Fenn1 1

Florida Institute of Technology, Melbourne, FL

2:00PM

Novel Approaches to Biomedical Imaging

Optimization of Time Gate Selection in Bi-exponential Fluorescence Lifetime Imaging via Sensitivity Analysis

Chairs: B. Hyle Park, Nozomi Nishimura

1

T. Omer1, N. Sinsuebphon1, L. Zhao1, X. Intes1, and J. Hahn1 Rensselaer Polytechnic Institute, Troy, NY

1:30PM

2:15PM

M. Kennedy1, B. Ning1, S. Seaman1, R. Chen2, Q. Zhou2, K. Shung2, S. Peirce1, and S. Hu1

K. Lee1,2, Y. Cui2, L. Lee1, and J. Irudayaraj2

Multi-parametric Photoacoustic Microscopy of Arterial Ligation University of Virginia, Department of Biomedical Engineering, Charlottesville, VA, 2 University of Southern California, Resource Center for Medical Ultrasonic Transducer Technology, Los Angeles, CA 1

Multiplexing Imaging of Single mRNA Isoforms for Dynamical Quantification in Live Cells 1

University of California Berkeley, Berkeley, CA, 2Purdue University, West Lafayette, IN

BMES 2014

187

Platform Sessions

Sat-2

Saturday | OCTOBER 25 | 2014

Platform Sessions Sat-2 1:30PM-3:00PM

2:30PM

Confocal Fluorescence Nanocytology: Detecting The Molecular Mechanisms Of Carcinogenesis J. Chandler1, Y. Stypula-Cyrus1, L. Almassalha1, B. Frese1, H. Subramanian1, and V. Backman1 1

Nortwestern University, Evanston, IL

Track: Undergraduate OP-Sat-2-20 - Room 204B

Undergraduate Research I Chairs: William Guilford, Kristine Ropella

2:45PM

Predictive Model Of Probe-Dependent Sampling Depth In Diffuse Reflectance Spectroscopy

1:30PM

W. Goth1, R. Hennessy1, M. Sharma1, and J. Tunnell1

J. Calvert1, A. Kreig1, S. Sinha1, and S. Myong1

1

The University of Texas at Austin, Austin, TX

Computational Prediction of G-quadruplex Formation 1

University of Illinois at Urbana-Champaign, Champaign, IL

1:40PM

Track: Cancer Technologies, Nano to Micro Technologies OP-Sat-2-19 - Room 103A

Nanotechnologies for Cancer II Chairs: Kaiming Ye, Debadyuti (Rana) Ghosh 1:30PM

Tumor-penetrating Nanocomplexes for siRNA Delivery to Pancreatic Cancer J. Lo1,2, E. Kwon1, M. Muzumdar1,3, Y. Ren1,2, T. Jacks1, and S. Bhatia1,4,5 MIT, Cambridge, MA, Harvard-MIT MD-PhD program, Boston, MA, Dana-Farber Cancer Institute, Boston, MA, 4Brigham and Women's Hospital, Boston, MA, 5Broad Institute of Harvard and MIT, Cambridge, MA

1

2

3

1:45PM

Spherical Nucleic Acids as an RNAi-Based Therapy for Glioblastoma E. Day1,2, S. Jensen2, C. Ko2, L. Hurley2, A. Stegh2, and C. Mirkin2 1

University of Delaware, Newark, DE, 2Northwestern University, Evanston, IL

2:00PM

Magnetic Fluid Hyperthermia Increases Bortezomib Cytotoxicity in Cancer Cells by Proteotoxic Stress M. Torres-Lugo1, M. Alvarez2, A. Castillo2, O. Soto2, and C. Rinaldi3 University of Puerto Rico, Mayaguez Campus, Mayaguez, Puerto Rico, 2University of Puerto Rico, Mayaguez Campus, Mayaguez, PR, Puerto Rico, 3University of Florida, Gainesville, Gainesville, FL 1

Spatiotemporal-Specific Antibody Signatures Associated with Tenofovir Microbicide Use L. Dunphy1, D. Archary2, K. Arnold1, K. Seaton3, J-A. Passmore2,4,5, L. Werner2, L. Morris4, G. Tomaras3, and D. Lauffenburger1 Massachusetts Institute of Technology, Cambridge, MA, 2Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, 3Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC, 4National Health Laboratory Services, Johannesburg, South Africa, 5Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, South Africa 1

1:50PM

Bioactive Glass Ceramics: The Ideal Synthetic Bone Substitute E. Mason1, M. Fenn1, and L. Hench1 1

Florida Institute of Technology, Melbourne, FL

2:00PM

Zeolite-loaded Alginate-chitosan Hydrogel Beads As A Topical Hemostat K. Christodoulides1, M. Bayomi1, Y. Choi1, P. Fathi1, A. Ghodasara1, J. Knazik1, K. Langan1, B. Miller1, M. Sikorski1, H. Thaker1, J. Titcomb1, O. Wonodi1, A. Behrens1, and P. Kofinas1 1

University of Maryland, College Park, MD

2:10PM

Evaluation of Screw-Tunnel Divergence and Graft Fixation Biomechanics using Flexible and rigid Reamer Systems for Anterior Cruciate Ligament Reconstruction M. Drazek1,2, K. Walley1,3, M. Perez-Viloria1, S. Okajima1,3, O. Manoukian1,4, A. Masoudi1,5, A. Chiloyan1,3, R. Nair1,3, M. Steiner6, and A. Nazarian1 Beth Israel Deaconess Medical Center, Boston, MA, 2Tufts University School of Medicine, Boston, MA, 3Boston University, Boston, MA, 4University of Connecticut, Storrs, CT, 5 Harvard Medical School, Boston, MA, 6New England Baptist Hospital, Roxbury Crossing, MA 1

2:15PM Platform Sessions

Sat-2

Prussian Blue Nanoparticles For Laser-Induced Photothermal Therapy Of Tumors H. Hoffman1, L. Chakrabarti1, M. Dumont1, A. Sandler1,2, and R. Fernandes1,2 Children's National Health System, Washington, DC, 2George Washington University, Washington, DC

1

2:30PM

Synergistic Antitumor Activity from Two-Stage Delivery of Piperlongumine and TRAIL Nanoparticles C. Sharkey1, J. Li1, and M. King1 1

Cornell University, Ithaca, NY

2:45PM

2:20PM

Mechanical Activity of Valve Interstitial Cells in Disease-like Conditions V. Pramil1, E. Farrar1, C. Mosher2, J. Richards1, and J. Butcher1 1

Cornell University, Ithaca, NY, 2Case Western University, Cleveland, OH

2:30PM

Imaging Collagen Architecture With Polarization-Sensitive Optical Coherence Tomography R. De La Rosa1, M. Villiger2,3,4, N. Uribe-Patarroyo2,3,4, and B. Bouma2,3,4 Brown University, Providence, RI, 2Wellman Center for Photomedicine, Boston, MA, Harvard Medical School, Boston, MA, 4Massachusetts General Hospital, Boston, MA

1

A Nano-plasmonic Sensor for Label-free Detection and Molecular Profiling of Cancer Exosomes

3

H. Im1, H. Shao1, Y. Park1, V. Peterson1, C. Castro1, R. Weissleder1,2, and H. Lee1

Ultrasound Imaging of Forearm Muscles for Decoding Hand Movements in Real Time

1

Massachusetts General Hospital, Boston, MA, 2Harvard Medical School, Boston, MA

2:40PM

M. Lahlou1, N. Akhlaghi1, H. Zafar1, and S. Sikdar1 George Mason Univiersity, Fairfax, VA

1

2:50PM

Using Nonlinear Dynamical Measures to Compare MEG Recordings of Epilepsy Patients with Normal Controls S. Subramanian1, S. Robinson2, S. Inati2, and R. Coppola2 1Johns Hopkins University, Baltimore, MD, 2National Institutes of Health, Bethesda, MD

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

188

BMES 2014

3:15PM-4:45PM Platform Sessions Sat-3

SATURDAY, October 25, 2014 3:15 PM - 4:45 PM PLATFORM SESSIONS – Sat - 3

2014 | OCTOBER 25 | Saturday

3:45PM

Incorporation of The Extra Domain A of Fibronectin (EDA) in Fibrin Matrices Mediates Activation of DCs and T-cell-dependent Tumor Regression Z. Julier1, M. Martino1, A. de Titta1, and J. Hubbell1 1

Track: Tissue Engineering, Orthopaedic and Rehabilitation Engineering OP-Sat-3-1 - Room 001A

Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

4:00PM

Effects of Age-Related Changes in Biomechanical and Biochemical Properties Upon Host Response to ECM

Muscular, Tendinous, Ligamental Tissue Engineering

S. LoPresti1,2, L. Zhang1,2, C. Dearth1, and B. Brown1,2

Chairs: George Christ,Vassilios Sikavitsas

4:15PM

3:15PM

Highly Functional Engineered Skeletal Muscle Tissues: From Rat to Human N. Bursac1 1

Duke University, Durham, NC

3:30PM

Mechanical Stimulation of Cellularized Polyurethane-Collagen Composite Meshes for Connective Tissue Applications P. Thayer1, E. Tong1, L. Dahlgren1, S. Guelcher2, and A. Goldstein1 1

University of Pittsburgh, Pittsburgh, PA, 2McGowan Institute for Regenerative Medicine, Pittsburgh, PA

1

Injectable Thermogelling Block Copolymers as Vaccine Delivery Devices J. Adams1 and S. Mallapragada1 1

Iowa State University, Ames, IA

4:30PM

Modulation of Cardiac Macrophages via Hydrogel-mediated IL-4 Delivery as a Strategy for Infarct Healing I. Somasuntharam1, S. Carroll1, M. Brown2, A. Salimath1, A. Garcia1, and M. Davis1,2 1

Georgia Institute of Technology, Atlanta, GA, 2Emory University, Atlanta, GA

Virginia Tech, Blacksburg, VA, 2Vanderbilt University, Nashville, TN

3:45PM

Keratin Hydrogels as a Cell and Growth Factor Delivery Vehicle for Treatment of Volumetric Muscle Loss

Track: Biomaterials OP-Sat-3-3 - Room 006A

H. Baker1,2, J. Passipieri1, S. Tomblyn3, M. Siriwardane1, C. Okoukoni1,2, C. Stewart4, M. Ellenburg3, L. Burnett3, and G. Christ1,2

Biomaterials Design II

Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, 2VT-WFU School of Biomedical Engineering and Sciences, Winston Salem, NC, 3KeraNetics, LLC, Winston Salem, NC, 4University of Virginia, Charlottesville, VA

Chairs: Nasim Annabi, Michael Davis

1

4:00PM

Tendon Tissue Engineering using a Mechanostimulator and Adult Stem Cell Seeded Decellularized Human Umbilical Vein V. Sikavitsas1 and B. Engebretson1 1

University of Oklahoma, Norman, OK

4:15PM

Contractile Composite Scaffolds for Skeletal Muscle Tissue Engineering D. Browe1, C. Simmonds1, K. McKeon-Fischer1, and J. Freeman1 Rutgers University, Piscataway, NJ

1

4:30PM

Localized BMP-4 Release For Improvement of the Engineered Enthesis A. Lee1, C. Lee1, M. Vidal1, and K. Baar1 1

University of California, Davis, Davis, CA

Track: Biomaterials, Cellular and Molecular Bioengineering OP- Sat - 3-2 - Room 001B

Biomaterials for Immunoengineering II Chairs: Lindsay Fitzpatrick, Anjelica Gonzalez 3:15PM

Immunomodulatory Scaffolds for Enhanced Cell Transplant R. Gower1, X. Zhang1, J. Zhang1, J. Liu1, C. Ricci1, and L. Shea1 1

Northwestern University, Chicago, IL

3:15PM

Near-infrared Light Triggerable Polysaccharides Double Network Hydrogel R. Luo1, Z. Lim1, W. Li2, P. Shi2, and C-H. Chen1 National University of Singapore, Singapore, Singapore, 2City University of Hong Kong, Hong Kong, Hong Kong

1

3:30PM

The Design of Hypoxia-Inducible Hydrogels via In Situ Oxygen Consuming Reaction K. Park1 and S. Gerecht1 1

Johns Hopkins University, Baltimore, MD

3:45PM

Hierarchical Design of Tunable Tissue-Like Collagen Materials

Platform Sessions

K. Blum1, T. Novak1, C. Neu1, and S. Voytik-Harbin1 1

Sat-3

Purdue University, West Lafayette, IN

4:00PM

Superbiocompatible Hydrogels for Islet Encapsulation Therapy: Tuning the Geometry of Hydrogels Prevents Foreign Body Immune Responses and Fibrosis to Enable Long-Term Blood Glucose Correction in Diabetic Mice O. Veiseh1, J. Doloff1, A. Vegas1, R. Langer1, and D. Anderson1 1

Massachusetts Institute of Technology, Cambridge, MA

4:15PM

Directing Cell Functions Using Bioorthogonally Clicked Multiblock Hybrid Copolymers S. Liu1, H. Zhang1, J. Fox1, and X. Jia1 1

University of Delaware, Newark, DE

3:30PM

Biodegradable Nanoellipsoidal Artificial Antigen Presenting Cells for Cancer Immunotherapy R. Meyer1, J. Sunshine1, K. Perica1, K. Aje1, J. Schneck1, and J. Green1 1

School of Medicine, Johns Hopkins University, Baltimore, MD

BMES 2014

189

Saturday | OCTOBER 25 | 2014

Platform Sessions Sat-3 3:15PM-4:45PM

3:30PM

How the Morphology of Osteocytes Contributes to their Mechanotransduction near Microdamage

Track: Biomechanics OP-Sat-3-4 - Room 006B

E. Budyn1,2, M. Bensidhoum3, E. Henry1, J-C. Auregan3, H. Petite3, and E. Deprez1

Biomechanics in Degeneration and Regeneration

Ecole Normale Superieure de Cachan, Cachan, France, 2University of Illinois at Chicago, Chicago, IL, 3University Paris Diderot, Paris, France

1

Chairs: Alesha Castillo, Kyle Allen

3:45PM

3:15PM

X. Wang1, X. Guan1, R. Browder1, D. McCaskill1, and R. Gan1

Finite Element Modeling of Normal and Pathological Chinchilla Ears

A Novel Biomechanical Model to Study Subchondral Microdamage Following Acute Knee Injury O. Kennedy1, B. Beutel1, and M. Lendhey1 1

Prevention of Cartilage Degeneration by Intraarticular Treatment with Lubricin-Mimetics in the Rat Following Anterior Cruciate Ligament Transection K. Samaroo1, M. Tan1, M. Demange2, A. Titan2, C. Carballo2, M. Sisto2, S. Rodeo2, D. Putnam1, and L. Bonassar1 Cornell University, Ithaca, NY, Hospital for Special Surgery, New York, NY 2

4:00PM

H. Li1 and G. Lykotrafitis1 1

4:15PM

Computational Analysis of Eustachian Tube Opening during Inflammatory Otitis Media in Children with Cleft Palate 1

Indentation Method to Map Mechanical Properties of Articular Surface to Identify Degenerated Regions S. Sim , , A. Chevrier , M. Garon , E. Quenneville , and M. Buschmann 1

2

2

University of Connecticut, Storrs, CT

J. Malik1 and S. Ghadiali1

3:45PM

1 2

University of Oklahoma, Norman, OK

Coarse-Grained Molecular Dynamics Modeling of Band-3 Protein Diffusion in the Defective Red Blood Cell Membrane

New York University School of Medicine, NY, NY

3:30PM

1

1

1

Ecole Polytechnique de Montreal, Montreal, QC, Canada, 2Biomomentum Inc., Laval, QC, Canada

1

The Ohio State University, Columbus, OH

4:30PM

A Computational-Experimental Approach for the In Situ Estimation of Aortic Valve Interstitial Cell Biophysical State R. Buchanan1 and M. Sacks1 1

The University of Texas at Austin, Austin, TX

4:00PM

Mechanobiology Assessment of Temporomandibular Disc Surfaces: A Nanoindentation and TEM Study. C. Juran1, A. Matuska1, and P. McFetridge1 1

University of Florida, Gainesville, FL

4:15PM

Microtechnologies for Cancer II

Genipin Effect on Soft Palates for the Treatment of Snoring and Obstructive Sleep Apnea

Chairs: Sihong Wang, Wei Li

J. Kuo1, P. Slusarewicz1, and T. Hedman1,2 1

3:15PM

Orthopeutics LP, Lexington, KY, 2University of Kentucky, Lexington, KY

Metastatic Cancer Cells Migration in 3D Collagen Matrix and Microtracks

4:30PM

The Effect of IGF-I Gene Therapy on the Mechanical Properties of Repaired Equine Cartilage D. Griffin1, K. Ortved1, A. Nixon1, and L. Bonassar1 1

Platform Sessions

Sat-3

Cornell University, Ithaca, NY

1

B. Koons1 and A. Nain1 1

Programmable Bacteria for Cancer Therapy and Diagnostics T. Danino1, A. Prindle2, O. Din2, G. Kwong1, S. Bhatia1, and J. Hasty 2

3:15PM

1

A Multiscale Particle Based Model of Platelets in Shear Flows: Correlating Numerical Simulations with In Vitro Results 1

1

Stony Brook University, Stony Brook, NY, 2University of Arizona, Tucson, AZ

MIT, Cambridge, MA, 2UCSD, La Jolla, CA

4:00PM

P. Zhang , J. Sheriff , C. Gao , M. Livelli , S. Pothapragada , N. Zhang , L. Zhang1, M. Slepian2, Y. Deng1, and D. Bluestein1 1

Virginia Tech, Blacksburg, VA

3:45PM

Chairs: Heather Hayenga, Rouzbeh Amini

1

Cornell University, Ithaca, NY

Decoupling Protrusion from Migration: A New Assay to Study Cancer Cell Protrusion Dynamics in the Absence of Migration

Multiscale Biomechanics

1

A. Rahman1, S. Carey1, C. Kraning-Rush1, B. Romero1, R. Williams1, and C. Reinhart-King1

3:30PM

Track: Biomechanics OP-Sat-3-5 - Room 006C

1

Track: Cancer Technologies, Nano to Micro Technologies OP-Sat-3-6 - Room 006D

1

Epidermal Growth Factor as a New Migration-Targeted Therapy for Pediatric Brain Tumors J. Rico1, T. Singh1, S. McCutcheon1, and M. Vazquez1 1

The City College of New York (CUNY), New York, NY

4:15PM

A Kinetic Model for Rapid Molecular Phenotyping of Resected Tissues during Cancer Surgery L. Sinha1, Y. Wang2, C. Yang1, A. Khan2, S. Leigh2, J. Liu2, and K. Tichauer1 Illinois Institute of Technology, Chicago, IL, 2Stony Brook University (SUNY), Stony Brook, NY

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

190

BMES 2014

3:15PM-4:45PM Platform Sessions Sat-3

2014 | OCTOBER 25 | Saturday

4:30PM

3:45PM

C. Wang1, X. Jiang1, C. Wilson1, A. Ponnuswami1, V. Caretti1, M. Monje1, G. Grant1, and F. Yang1

C-H. Lee1, C. Carruthers2, B. Good3, S. Ayoub1, R. Gorman4, J. Gorman4, and M. Sacks1

A Comparative Study Of Patient-Derived Primary Brain Tumor Cells Using 3D Biomimetic Hydrogels 1

Stanford University, Stanford, CA

The University of Texas at Austin, Austin, TX, 2Metronic, Minneapolis, MN, 3Pennsylvania State University, State College, PA, 4University of Pennsylvania, Philadelphia, PA

1

Track: Stem Cell Engineering, Tissue Engineering OP-Sat-3-7 - Room 007A

4:00PM

Impact of Transcatheter Aortic Valve Oversizing on Leaflet Stress and Strain Distribution M. Abbasi1 and A. Azadani1

Stem Cells in Translational Science

1

Chairs: Eduardo Silva, Stephanie Willerth

University of Denver, Denver, CO

4:15PM

3:15PM Invited

Spatiotemporal Mapping of De Novo Tissue Genesis by Stem Cells & Tissue-Implant Interactions C. Heu1, S. Moore2, U. Knothe3, R. Segal1, T. Piepergerdes4, and M. Knothe Tate1 University of New South Wales, UNSW Sydney, Australia, 2Case Western Reserve University, Cleveland, OH, 3Cleveland Clinic, Cleveland, OH, 4Vanderbilt University, Nashville, TN

1

Hemodynamic Changes in Coronary Arteries Due to Regional Aortic Root Pathologies H. Mohammadi1, R. Cartier2, and R. Mongrain1 1

Preparation of Native Extracellular Matrix for Stem Cell-based Salivary Gland Regeneration. A. Malakhov1, B-X. Zhang1, H. Wang1, A. Lin1, D. Dean1, S. Weintraub1, X-D. Chen1, and C-K. Yeh2 UTHSC, San Antonio, TX, 2STVHCS, San Antonio, TX

McGill University, Montreal, QC, Canada, 2Montreal Heart Institute, Montreal, QC, Canada

4:30PM

Stent Strut Geometry Affects Endothelial Cell Migration J. Jiménez1, P-J. Wang1, and P. Davies1 1

3:30PM

1

Integrated Experimental-Computational Modeling of Mitral Valve Intestitial Cell Deformation Under In Situ Physiological Loading

University of Pennsylvania, Philadelphia, PA

Track: Drug Delivery OP-Sat-3-9 - Room 007D

Targeted Delivery II

3:45PM

A Human iPS-derived In Vitro Model of 3D Vascularized Cardiac Muscle

Chairs: Emily Day, Junghae Suh

Y. Kurokawa1, D. Tran1, M. Moya1, A. Sobrino1, L. Alonzo1, C. Heylman1, C. Tu1, L. Lock1, C. Hughes1, B. Conklin2, and S. George1

3:15PM

1

University of California, Irvine, Irvine, CA, Gladstone Institutes, San Francisco, CA 2

4:00PM

R. Zhu1, A. Blazeski1, K. Boheler1, and L. Tung1

B. Lin , T. Lu , J. Kim , M. Sullivian , K. Tobita , G. Salama , and L. Yang 1

1

Albumin Nanoparticles for Targeted EDTA Delivery to Reverse Elastin Specific Medial Calcification

1

1

Clemson University, Clemson, SC

3:45PM

Beat Whole Decellularized Mouse Heart with Human Induced Pluripotent Stem (iPS) Cells 1

3:30PM

1

4:15PM

1

Barrow Neurological Institute, Phoenix, AZ

Y. Lei1 and N. Vyavahare1

The Johns Hopkins University, Baltimore, MD

1

R. Sirianni1 and A. Prakapenka1 1

Stable Human Induced Pluripotent Stem Cell-derived Cardiomyocyte Syncytium That Supports Paced Electrical Activities and Responds to IKr Blockage 1

Targeting Drug Delivery to Motor Neurons in the Spinal Cord

1

University of Pittsburgh, Pittsburgh, PA

Cystathionine-Gamma-Lyase Enzyme Prodrug Therapy Targeted to Tumor Vasculature in Immune Competent Model J. Krais1, C. Kurkjian2, and R. Harrison1 University of Oklahoma, Norman, OK, 2University of Oklahoma Health Sciences Center, Oklahoma City, OK

1

Track: Cardiovascular Engineering OP-Sat-3-8 - Room 007B

4:00PM

Heart Valves and Stents II

M. Ho , M. Lam , M. Yamagami , C. Guenther , and J. Suh

Chairs: Mehdi Nikkah, Gulden Camci-Unal 3:15PM

Physiological Relevant Shear Stress and Flexure in Developing Valvular Tissues S. Rath1, A. Villegas1, M. Salinas1, and S. Ramaswamy1 1

1

Design of an In Vitro Simulation Pipeline for the Development of Computational Mitral Valve Modeling C. Bloodworth IV1, E. Pierce1, T. Easley1, M. Toma1, A. Khalighi2, C-H. Lee2, M. Sacks2, A. Siefert1, M. Jensen1, and A. Yoganathan1 Georgia Institute of Technology, Atlanta, GA, 2University of Texas at Austin, Austin, TX

1

1

1

1

1

Rice University, Houston, TX

4:15PM

Development of Poly-aspartic Acid Peptide Linked PLGA-based Nanoparticles for Bone Targeting E. Carbone1, X. Yu1, T. Jiang1, C. Nelson1, H. Kan1, and W. Lo1 1

Florida International University, Miami, FL

3:30PM

Sat-3

Protease-activatable Virus Based on Adeno-associated Virus for Cardiovascular Disease Therapy 1

UConn Health Center, Farmington, CT

4:30PM

Plasma Proteins Alter the Vascular Wall Adhesion of Drug Carriers in a Material & Donor Specific Way D. Sobcynski1, P. Charoenphol1, P. Onyskiw1, K. Namdee1, A. Thompson1, and L. Eniola-Adefeso1 1

University of Michigan, Ann Arbor, MI

BMES 2014

Platform Sessions

191

Saturday | OCTOBER 25 | 2014

Platform Sessions Sat-3 3:15PM-4:45PM

3:45PM

Track: Respiratory Bioengineering, Biomechanics OP-Sat-3-10 - Room 008B

Mechanobiology in the Respiratory System Chairs: Konstantin Birukov, Rebecca Heise 3:15PM

1

Northwestern University, CHICAGO, IL

4:00PM

Dynamic Simulation and Neuromuscular Control of Balance in Children with Cerebral Palsy: Implications for Rectus Femoris Transfer Surgery M. Mansouri Boroujeni1 and J. Reinbolt1

D. Leckband1, S. Choi1, and S. Dudek2

4:15PM

University of Illinois at Urbana, Urbana, IL, 2University of Illinois at Chicago, Chicago, IL

3:30PM

The Role of MicroRNAs in Ventilator Induced Lung Injury (VILI) and Inflammation K. Nelson1, C. Bobba1, B. Whitson1,2, and S. Ghadiali1,3

1

University of Tennessee, Knoxville, TN

Optimizing the Spinal Cord: Finding the Best Sensory Input to Improve Walking after Injury J. White1,2, L. McCollough3, K. Tansey2,4, and S. DeWeerth1,2 Georgia Institute of Technology, Atlanta, GA, 2Emory University, Atlanta, GA, 3Shepherd Center, Atlanta, GA, 4Atlanta VA Medical Center, Atlanta, GA

1

Ohio State University, Columbus, OH, 2Department of Surgery and Division of Cardiac Surgery, Columbus, OH, 3Department of Pulmonary, Allergy, Critical Care, and Sleep, Columbus, OH

4:30PM

3:45PM

I. Shojaei1 and B. Bazrgari1

1

Paxillin-GEF-H1-MAPK Signalosome and Pathologic Mechanotransduction in Mechanically Ventilated Lung G. Gawlak1, X. Tian1, A. Birukova1, and K. Birukov1 1

University of Chicago, Chicago, IL

4:00PM

Enhanced Matrix Elastin Production and Organization Using Pentagalloyl Glucose in Pulmonary Fibroblast Cultures V. Parasaram , N. Nosoudi , and N. Vyavahare 1

1

1

1

Clemson University, Clemson, SC

An Analytical Solution For Obtaining The Lumbar Spine Segmental Rotations 1

University of Kentucky, Lexington, KY

Track: Drug Delivery, Cancer Technologies OP-Sat-3-12 - Room 103B

Cancer Drug Delivery III Chairs: Srivatsan Kidambi, Joseph Kinsella 3:15PM

4:15PM

Targeted Polymeric Nanoparticles for Leukemia Cell-Specific Delivery of Pediatric Chemotherapy

R. Wise1, N. Zaman1, A. West2, P. Gratzer1, K. Billiar3, and G. Maksym1

1

Chronic Tone and Substrate Stiffness Modulation Alters Airway Smooth Muscle Contractile Phenotype Dalhousie University, Halifax, NS, Canada, 2University of Manitoba, Winnipeg, MB, Canada, 3 Worcester Polytechnic Institute, Worcester, MA 1

4:30PM

Age Related Changes in Pulmonary Mechanics and Inflammatory Response to Experimental Ventilator Induced Lung Injury J. Herbert1, M. Valentine1, P. Patel1, A. Reynolds1, R. Pidaparti2, and R. Heise1 1

Sat-3

Y. Lan1, J. Yao1, and J. Dewald1

Genetic Variants of Cytoskeletal Elements Linked to Acute Lung Injury Impair Lamellipodia Dynamics and Endothelial Wound Healing 1

Platform Sessions

Increased Shoulder Abduction Loads Decrease Voluntary Finger Flexion in Individuals with Chronic Stroke

Virginia Commonwealth University, Richmond, VA, 2University of Georgia, Athens, GA

Track: Neural Engineering, Orthopaedic and Rehabilitation Engineering OP-Sat-3-11 - Room 201

Neuro-rehabilitation Biomechanics Chairs: Jeffrey Capadona, Ayesgul Gunduz 3:15PM

Predicting Metabolic Costs of Pathologic Gait in Cerebral Palsy K. Steele1 and M. Schwartz2,3 University of Washington, Seattle, WA, 2Gillette Children's Specialty Healthcare, St. Paul, MN, 3University of Minnesota, Minneapolis, MN

V. Krishnan1,2, X. Xu3, R. W. Mason2, X. Jia1, and A. K. Rajasekaran1 University of Delaware, Newark, DE, 2Nemours Alfred I DuPont Hospital for Children, Wilmington, DE, 3Massachusetts Institute of Technology, Cambridge, MA

3:30PM

Functionalization of Gold Nanorods for Cancer Cell Imaging, Drug Delivery and Photothermal Therapy D. Pacardo1, B. Neupane2, M. Rikard1, Y. Lu1, R. Mo1, G. Wang2, F. Ligler1, and Z. Gu1 1 North Carolina State University and University of North Carolina, Raleigh, NC, 2North Carolina State University, Raleigh, NC

3:45PM

Novel Functionalization of Single Walled Carbon Nanohorns for Controlled Chemotherapeutic Delivery A. Pekkanen1, M. DeWitt1, and M. Rylander1 1

Virginia Tech, Blacksburg, VA

4:00PM

A Magnetic Field to Target Paramagnetic Nanoparticles in a Tumor Model of Glioblastoma M. Navati1, S. Lopez1, M. Urban-Maldonado1, M. Silva1, J. Segall1, D. Spray1, and J. Friedman1 1

Yeshiva University, Bronx, NY

1

3:30PM

Information Theoretic Metrics as Biomarkers of Parkinsonian Symptom Severity C. Anderson1 and A. Dorval1 1

University of Utah, Salt Lake City, UT

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

192

BMES 2014

4:15PM

Oxidized Graphene Nanoribbons As A Novel Delivery System For The Anticancer Sphingolipid Ceramide C. Suhrland1, B. Sitharaman1, and J-P. Truman1 1

SUNY Stony Brook, Stony Brook, NY

3:15PM-4:45PM Platform Sessions Sat-3

2014 | OCTOBER 25 | Saturday

4:30PM

Thermo-responsive, Multimodal Imaging Enabled Nanoparticles Towards Cancer Therapy N. Pandey1, A. Wadajkar1, V. Sundaresan1,2, E. Hernandez2, J-T. Hsieh2, L. Tang1,2, J. Yang3, and K. Nguyen1,2 University of Texas at Arlington, Arlington, TX, 2The University of Texas Southwestern Medical Center, Dallas, TX, 3The Pennsylvania State University, University Park, PA

1

Track: Undergraduate OP-Sat-3-14 - Room 204B

Undergraduate Research II Chairs: William Guilford, Kristine Ropella 3:15PM

Track: Neural Engineering, Biomedical Imaging and Optics OP-Sat-3-13 - Room 202A

Macro/micro Design for Neurotechnologies / Networked Neural Sensors, Actuators, and Instrumentation

1

Washing with Human Albumin Improves the Ability of Stored Red Blood Cells to Perfuse an Artificial Microvascular Network R. Abidi1, N. Piety1, and S. Shevkoplyas1 1

Purdue University, West Lafayette, IN

System for Integrated Neural Imaging, Recording and Stimulation 2

1

Ultrasound Neuromodulation: Field Overview and Observations in the Vagus Nerve of a Rat E. Juan1

University of Missouri-Columbia, Kansas City, MO, 2Duke University, Durham, NC

3:55PM

New Chameleon NanoCluster Beacons for Emission-Spectrum-Based SNP Detection D. Imphean1, R. Batson1, J. Obliosca1, and H-C. Yeh1

UPR-Mayagüez, Mayagüez, PR

1

4:00PM

Nanowire Electrophysiology for In Vivo Measurement of the C. elegans Neuromuscular Junction D. Gonzales1, B. Avants1, D. Vercosa1, and J. Robinson1,2 Rice University, Houston, TX, 2Baylor College of Medicine, Houston, TX

Single-cell Transfection Within a 3D Tumor Model Using Optoporation M. Maurer1, M. Monaghan2, Y. Möller3, M. Olayioye3, and K. Schenke-Layland1,2

4:15PM

S. Kodandaramaiah , F. Flores , , G. Holst , I. Wickersham , E. Brown , , C. Forest3, and E. Boyden1 3

4:05PM

Eberhard-Karls-University Tübingen, Tübingen, Germany, 2Fraunhofer Institute for Interfacial Engineering and Biotechnology (IGB), Stuttgart, Germany, 3University of Stuttgart, Stuttgart, Germany

The Multipatcher: A Robot for High Density Measurement of Intracellular Recordings In Vivo 1 2

University of Texas at Austin, Austin, TX

1

4:15PM

1

The Effect of Lovastatin Treatment on Activated Endothelial Cell Gene Expression and Monocyte Adhesion K. Henderson1, C. Fernandez2, W. Reichert2, and G. Truskey2

Purdue University, West Lafayette, IN, 2Indiana University, Bloomington, IN

3:45PM

1

University of Houston, Houston, TX

3:45PM

3:30PM

1

Duke University, Durham, NC

3:35PM

P. Irazoqui1

Z. Liu and H. Cheng

University of Virginia, Charlottesville, VA

S. Perez1, C. Fernandez1, W. Reichert1, and G. Truskey1

Implantable Networks of Wireless Nanoelectronic Nodes

1

1

Promoting Elastin Production in Tissue-Engineered Blood Vessels by Inhibiting microRNA-29 in Human Neonatal Dermal Fibroblasts

3:15PM

1

S. Hansen1 and B. French1

3:25PM

Chairs: Pedro Irazoqui, Mehmet Kaya

1

AAV9-based Gene Delivery for Cardiac Regeneration via Fibroblast Reprogramming

1

1 2

Computational Fluid Dynamic Modeling of 3D Scaffolds in Dynamic Culture

Massachusetts Institute of Technology, Cambridge, MA, 2Massachusetts General Hospital, Cambridge, MA, 3Georgia Institute of Technology, Atlanta, GA

H. Ko1, B. Nguyen1, and J. Fisher1

4:30PM

4:25PM

1

Principles of High Fidelity, High Density 3D Neural Recording C. Moore-Kochlacs , , J. Scholvin , J. Kinney , J. Bernstein , Y. Yoon , S. Arfin2, N. Kopell1, and E. Boyden2 1 2

2

2

2

2

Boston University, Boston, MA, 2Massachusetts Institute of Technology, Cambridge, MA

1

1

Platform Sessions

University of Maryland, College Park, College Park, MD

Sat-3

Postural Sway as a Correlate of Psychosis Proneness and Social Behavior H. Bothwell1 and D. Evans2 Bucknell University, Lewisburg, PA, 2Geisinger-Bucknell Autism and Developmental Medicine Institute, Lewisburg, PA

1

4:35PM

An Enzyme-activatable, Receptor-targeted Filamentous Viral Nanoparticle P. Chariou1, K. Lee1, and N. Steinmetz1 1

Case Western Reserve University, Cleveland, OH

BMES 2014

193

SATURDAY

160 159 141 142

180 179 161 162

200 199 181 182

220 219 201 202

240 239 221 222

260 259 241 242

280 279 261 262

300 259 281 282

138 123

158 143

178 163

198 183

218 203

238 223

258 243

278 263

298 283

96 85

117 116 104 105

137 136 124 125

157 156 144 145

177 176 164 165

197 196 184 185

217 216 204 205

237 236 224 225

257 256 244 245

276 265

297 296 284 285

75 66

95 86

54 47

74 67

94 87

115 114 106 107

135 134 126 127

155 154 146 147

175 174 166 167

195 194 186 187

215 214 206 207

235 234 226 227

255 254 46 247

275 274 266 267

295 294 286 287

53 48

73 68

93 88

113 108

133 128

153 148

173 168

193 188

213 208

233 228

253 248

273 268

293 288

52 49

72 69

92 89

51 50

71 70

91 90

112 111 109 110

132 131 129 130

152 151 149 150

172 171 169 170

192 191 189 190

212 211 209 210

232 231 229 230

252 251 249 250

272 271 269 270

292 291 289 290

336 335 325 326

348 347 337 338

360 359 349 350

372 371 361 362

384 383 373 374

396 395 385 386

408 407 397 398

420 419 409 410

432 431 421 422

444 443 433 434

456 455 445 446

468 467 457 458

480 479 469 470

334 327

346 339

358 351

370 363

382 375

394 387

406 399

418 411

430 423

442 435

454 447

466 459

478 471

333 332 328 329

345 344 340 341

357 356 352 353

369 368 364 365

381 380 376 377

393 392 388 389

405 404 400 401

417 416 412 413

429 428 424 425

441 440 436 437

453 452 448 449

465 464 460 461

477 476 472 473

331 330

343 342

355 354

367 366

379 378

391 390

403 402

415 414

427 426

439 438

451 450

463 462

475 474

542 541 529 530

552 551 543 544

566 565 553 554

580 579 567 568

594 593 581 582

608 607 595 596

622 621 609 610

636 635 623 624

650 649 637 638

664 663 651 652

678 677 665 66

688 687 679 680

702 701 689 690

540 531

550 545

564 555

578 569

592 583

606 597

620 611

635 625

648 639

662 653

676 66

686 681

700 691

539 538 532 533

549 548 546 547

563 562 556 557

577 576 570 571

591 590 584 585

605 604 598 599

619 618 612 613

633 635 626 627

647 646 640 641

661 660 654 655

675 674 668 669

685 684 682 683

699 698 692 693

537 536 534 535

561 560 558 559

575 574 572 573

589 588 586 587

603 602 600 601

617 616 614 615

631 630 628 629

645 644 642 643

659 685 656 657

673 672 670 671

REFRESHMENT BREAKS

140 139 121 122 118 103 97 84

76 65

55 46

REFRESHMENT BREAKS

120 119 101 102 98 83

56 45

REFRESHMENT BREAKS

99 82 78 63

57 44

697 696 694 695

100 81 79 62

58 43

P O S T E R S

80 61 59 42

P O S T E R S

60 41

523 522 520 521

509 508 506 507

525 524 518 519

511 510 504 505

526 517

512 503

528 527 515 516

514 513 501 502

319 318 307 306

321 320 316 317 309 308 304 305

322 315 310 303

324 323 313 314 312 311 301 302

31 30 11 10

32 29 12 9

33 28 13 8

34 27 14 7

35 26 15 6

36 25 16 5

37 24 17 4

38 23 18 3

39 22 19 2

40 21 20 1

BMES 2014

194

137 236 237 336 337 436 437 536 537 636

9:30AM – 1:00pm Poster Session Sat

2014 | october 25 | Saturday

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am

SATURDAY, October 25, 2014

Biomaterials

Poster Viewing with Authors – 9:30 AM – 10:30 AM

P-Sat-13 Efficacy And Degradation Analysis of Heat Labile Antibiotic Compounds Subjected To Thermal Conditions Indicative Of PMMA Curing Processes

Bioinformatics, Computational and Systems Biology

J. Chang1,2, T. Hess1, and M. DeSilva1

P-Sat-1 Computational Modeling of Integrated HDAC5 Response to Electrical and Neurohormonal Stimuli J. Saucerman1, M. Rhoads1, R. North1, and W. Boyd1 1

Naval Medical Research Unit San Antonio, San Antonio, TX, 2Naval Research Enterprise Internship Program, San Antonio, TX

1

P-Sat-15 Study of the Second Virial Coefficient of Cowpea Mosaic Virus Under Varying pH and Ionic Strength Using Composition-Gradient Multi-Angle Light Scattering D. Acosta1, Y. Ma1, A. Wen1, R. Podgornik2,3,4, V. Parsegian2, R. French1, and N. Steinmetz1

University of Virginia, Charlottesville, VA

Case Western Reserve University, Cleveland, OH, 2University of Massachusetts, Amherst, MA, 3J. Stefan Institute, Ljubljana, Slovenia, 4University of Ljubljana, Ljubljana, Slovenia

1

P-Sat-2 PDGFRα And PDGFRβ Cell Surface Levels Are Positively Correlated With Cell Confluency In Vitro X. Guo1, O. Imarenezor1, S. Chen1, and P. Imoukhuede1 1

University of Illinois at Urbana-Champaign, Urbana, IL

P-Sat-3 An Agent-Based Model Predicts How Pancreatic Islet Size Affects Revascularization and Engraftment Potential Following Transplantation M. Lataillade1 and S. Peirce-Cottler1 1

University of Virginia, Charlottesville, VA

P-Sat-4 Examining The Partitioning Of Angiogenic Receptors In Vitro University of Illinois, Urbana-Champaign, Urbana, IL

V. Lanka1, J. Holmes2, and W. Richardson2 University of Virginia, Ashburn, VA, 2University of Virginia, Charlottesville, VA

P-Sat-6 Modeling Temporal Dynamics of Infarct Collagen Turnover W. Pilcher1, J. Holmes1, and W. Richardson1 1

University of Virginia, Charlottesville, VA

P-Sat-7 Experimental and Computational Analysis of Cardiomyocyte Generation from iPS Cells via Temporal Modulation of Wnt Signaling T. Jones1 and P. Aurora1 1

University of Virginia, Charlottesville, VA

P-Sat-8 Automated Validation and Systematic Revision of a Cardiac Hypertrophy Signaling Model University of Virginia, Charlottesville, VA

P-Sat-9 Integrating the Effects of Exercise to the UVa/Padova Type 1 Diabetes Simulator N. Frantz1, K. Turksoy1, M. Sertbas1, J. Feng1, and A. Cinar1 1

Illinois Institute of Technology, Chicago, IL

P-Sat-10 Pan-Cancer Analysis for Identifying Proteins Related to Cancer Stage S. Mishra1, C. Kaddi1, and M. Wang1 1

Case Western Reserve University, Cleveland, OH, 2Massachusetts Institute of Technology, Cambridge, MA

1

P-Sat-17 Comparison of Mechanical Testing Methods for Biomaterials: Nanoindentation, Pipette Aspiration, and Macroscale Testing K. Tong1, R. Blaho1, C. Buffinton1, and D. Ebenstein1 Bucknell University, Lewisburg, PA

M. Burbano1, T. Wilson2, P. Valderrama2, J. Blansett3, C. Wadhwani4, P. Choudhary1, and D. Rodrigues1 1 3

University of Texas at Dallas, Richardson, TX, 2Private Practice of Periodontics, Dallas, TX, Private Practice of Periodontics, Rogers, AR, 4University of Washington, Seattle, WA

P-Sat-19 Fabrication of a Human Lamina Cribosa Mimic by Co-electrospinning J. Hochstein1,2, M. Earley1,3, A. Rajabi Zamani1, G. Collins1, B. Mantilla1, and M. Jaffe1 New Jersey Institute of Technology, Newark, NJ, 2Johns Hopkins University, Baltimore, MD, 3Virginia Tech, Blacksburg, VA

1

P-Sat-20 Tuning an In Vitro Hydrogel Microenvironment with Fibroblast Co-Culture for Improved Skeletal Myoblast Delivery N. Rao1, G. Agmon1, M. Tierney2, A. Sacco2, and K. Christman1 1

UC San Diego, La Jolla, CA, 2Sanford-Burnham Medical Research Institute, La Jolla, CA Poster Session

P-Sat-21 Characterization of Lactose-Containing Two-Solution Bone Cements

A. Paap1, K. Ryall1, R. North1, and J. Saucerman1 1

S. Ahmadmehrabi1,2, S. Akbari2, and P. Hammond2

P-Sat-18 Analysis of Cement Particles Present in Human Biopsies Affected by Periimplantitis

P-Sat-5 A Computational Model of Collagen Fibrillogenesis 1

P-Sat-16 Creating Biomimetic Neighbors for In Vitro 3D β-Cell Culture systems

1

A. Storm1, W. Woods1, and P. Imoukhuede1 1

Moved to P-Sat-51

Georgia Institute of Technology, Atlanta, GA

P-Sat-11 Towards Optimizing the Production of Pertussis Vaccine Using Computational Modeling

Sat

E. Bentley1, L. Rodriguez1, J. Chari1, S. Aghyarian1, and D. Rodrigues1 1

The University of Texas at Dallas, Richardson, TX

P-Sat-22 Determination of Variables Affecting Degradation of Polyethylene Glycol Hydrogels J. Redington1, E. Jain2, S. Sell2, and S. Zustiak2 1

Shorter University, Suwanee, GA, 2Saint Louis University, St Louis, MO

P-Sat-23 Comparative Analysis of Chemical and Photochemical Crosslinking of Polyacrylamide Gels A. Karadaghy1, H. Stevenson1, and S. Zustiak1 1

Saint Louis University, St Louis, MO

M. Bloom1, H. Truong1, M. Gray1, E. Hewlett1, and J. Papin1 1

Undergraduate Research

9:30 AM - 1:00 PM POSTER SESSIONS

University of Virginia, Charlottesville, VA

See page 194 for Poster floor plan

BMES 2014

195

Poster Session Sat 9:30AM – 1:00pm

saturday | october 25 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM P-Sat-24 Conditioning Cells to Microenvironmental Cues

P-Sat-36 Bio-Corrosion Evaluations Using Dynamic Electrochemical Methods

S. Syed1 and S. Zustiak1

H. Lundin1

1

Saint Louis University, St Louis, MO

P-Sat-37 Effects Of Dual Frequency Excitation On Cavitation Of Microbubbles

A. Williams1, T. Alexander2, L. Lozeau2, and T. Camesano2

1

Vanderbilt University, Nashville, TN, 2Worcester Polytechnic Institute, Worcester, MA

P-Sat-26 Genetically Engineered Fluorescent Plant Viral Nanoparticles as Versatile Optical Imaging Agents A. Nagarajan1, S. Shukla1, C. Dickmeis2, R. Fischer2, U. Commandeur2, and N. Steinmetz1 1

Case Western Reserve University, Cleveland, OH, 2RWTH Aachen, 52074 Aachen, Germany

P-Sat-27 Investigating the Effect of Conducting Polymer Graphene Oxide Composite Coatings on Magnesium Corrosion H. Li1, K. Catt1, and X. Cui1 1

University of Pittsburgh, Pittsburgh, PA

P-Sat-28 Analyzing ROS Generation from Magnetic Nanoparticles in an Alternating Magnetic Field and its Role in Iintracellular Hyperthermia C. Oliver1, R. Wydra2, D. Cochran2, K. Anderson2, T. Dziubla2, and J. Hilt2 1

University of Connecticut, Storrs, CT, 2University of Kentucky, Lexington, KY

P-Sat-29 Self Assembled Organosilane Coatings For Resorbable Devices O. Jackson1, A. Patil1, and E. Beniash1 1

University of Pittsburgh, Pittsburgh, PA

P-Sat-30 Syndesomes Enhance Cutaneous Wound Healing in Diabetic Mice G. Singh1, S. Das1, M. Martinez1, A. Dunn1, and A. Baker1 1

University of Texas, Austin, TX

P-Sat-31 Designing a SiO2-coated Gd-loaded Macromolecular Magnetic Resonance Contrast Agent L. Randolph1, M. Bruckman1, and N. Steinmetz1,2 Case Western Reserve University, Cleveland, OH, 2Case Western Reserve University School of Medicine, Cleveland, OH

1

P-Sat-32 Interface of Physics and Biology: Engineering Virus-Based Nanoparticles for Biophotonics D. Kernan1, A. Wen1, M. Infusino1,2, A. De Luca1,3, G. Strangi1,3, and N. F. Steinmetz1 Case Western Reserve University, Cleveland, OH, 2Universidad San Francisco de Quito, Quito, Ecuador, 3University of Calabria, Rende, Italy

1

Sat

Wichita State University, Park City, KS

P-Sat-25 Characterization of a Collagen Film at Various pH and Temperatures Using a QCM-D 1

Poster Session

1

P-Sat-33 Methods for Coating Microspheres with Mesenchymal Stem Cell-Derived Matrix R. Reese1, A. Tondon1, C. Gregory2, and R. Kaunas1 1

Texas A&M University, College Station, TX, 2Texas A&M Health Science Center, Temple, TX

P-Sat-34 Self-Assembly of DNA-Based Responsive Soft Biomaterials: A Computational and Experimental Approach J. Dominguez1, Z. Goddard1, S. Benner2, C. Hall2, and T. Betancourt1 1

Texas State University, San Marcos, TX, 2North Carolina State University, Raleigh, NC

A. Smith1, L. Phillips1, S. Guo2, X. Jiang2, and P. Dayton1 University of North Carolina, Chapel Hill, NC, 2North Carolina State University, Raleigh, NC

P-Sat-38 Optimizing Electrospun Fiber Mats For Use As Mock Blood-Brain Barriers M. Mendive1, V. Pensabene2,3, D. Balikov3, and H-J. Sung3 SyBBURE-Searle Undergraduate Research Experience, Vanderbilt University, Nashville, TN, 2Vanderbilt Institute for Integrative Biosystems Research and Education, Vanderbilt University, Nashville, TN, 3Department of Biomedical Engineering, Vanderbilt University, Nashville, TN

1

P-Sat-39 Random Sequential Adsorption of Proteins on Polymer-covered Surfaces: A Simulation-based Approach A. Gore1, E. Dumont2, P. Katira1, and H. Hess1 Columbia University, New York, NY, 2The Joan and Irwin Jacobs Technion-Cornell Innovation Institute, New York, NY

1

P-Sat-40 Study of the Effects of Detoxification Treatments on Titanium used in Osseointegrative Applications S. Wheelis1, I. Gindri1, S. Sridhar1, P. Valderramma2, T. Wilson3, and D. Rodrigues1 1 3

University of Texas at Dallas, Richardson, TX, 2Private Practice of Periodontics, Dallas, TX, Baylor College of Dentistry, Dallas, TX

P-Sat-41 Effect of Lateral Retinacular Release after Total Knee Replacement on Patellar Kinematics and Patellofemoral Contact Pressure at Varying Patellar Component Thicknesses J. Rodriguez1, X. Xie1,, R. Rusly1, A. C. Clark1, F. Voss2, J. Desjardins1, and M. Laberge1 Clemson University, Clemson, SC, 2University of South Carolina, School of Medicine, Clemson,

1

SC P-Sat-42 Improved Magnetically Responsive Gels for Controlled Drug Delivery C. Roco1,2, S. Kennedy1,2, C. Cezar1,2, A. Déléris1,2, S. Patrizia1,2, and D. Mooney1,2 Harvard School of Engineering and Applied Science, Cambridge, MA, 2Wyss Institute for Biologically Inspired Engineering, Boston, MA

1

P-Sat-43 Biomimetic Nanofiber Microenvironments for Metastatic Tumor Cell Line Development R. Banoub1, T. Nelson1, J. Lang1, and J. Lannutti1 1

The Ohio State University, Columbus, OH

P-Sat-44 Electrospun Nanofibers as a Biomimetic Platform for Melanoma Migration S. Bushman1, T. Nelson1, R. Underiner1, X. Guan1, A. Holderbaum1, J. Lannutti1, and C. Burd1 Ohio State University, Columbus, OH

1

P-Sat-45 Synthesis of Mg-Microbeads using Electrospraying Technique T. Campbell1, R. Blount2, and N. Bhattarai2 University of Rhode Island, Kingston, RI, 2North Carolina A&T State University, Greensboro, NC

1

P-Sat-46 Fabrication and Characterization of 3D-Printed Pore Architecture Scaffolds for Mesenchymal Stem Cell Adhesion and Proliferation M. Prendergast1, K. Ferlin1, D. Kaplan2, and J. Fisher1 University of Maryland - College Park, College Park, MD, 2Food and Drug Administration, Silver Spring, MD

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

196

BMES 2014

9:30AM – 1:00pm Poster Session Sat

2014 | october 25 | Saturday

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am P-Sat-47 Characterizing Gold Nanoparticle Interactions with a Supported Lipid Bilayer in the Presence of Humic Acid C. Bailey1, E. Kamaloo1, K. Waterman1, K. Wang1, and T. Camesano1 1

R. Blaho1, K. Tong1, C. Buffinton1, D. Ebenstein1, and E. Buffinton2 1

Bucknell University, Lewisburg, PA, 2Lafayette College, Easton, PA

P-Sat-48 Design And Manufacture Of Novel Polymer Neural Electrodes For Blast Testing

P-Sat-68 Structural and Effective Material Properties of the Anterior, Lateral, and Posterior Human Rib Bone

G. Terziev1, G. Wood1, J. Shridharani1, A. Alshareef1, B. Bigler1, E. Skolnick1, and C. Bass1

T. Comte1, A. Lau1, and M. Kindig2

1

Duke University, Durham, NC

P-Sat-49 Fabrication of Porous PDMS Thin Films as a Microfluidic Blood Brain Barrier N. Braman1,2, L. Hofmeister1,2, V. Pensabene2,3, D. Schaffer3, C. Marasco1,2,3, and J. Wikswo2,3 Searle SyBBURE Undergraduate Research Program, Nashville, TN, Vanderbilt University, Nashville, TN, 3Vanderbilt Institute for Integrative Biosystems Research and Education, Nashville, TN

1

1

University of North Carolina, Chapel Hill, NC, 2University of Virginia, Charlottesville, VA

P-Sat-69 Factors that Contribute to Inter-Subject Variation in Human Liver and Spleen Material Properties S. Zwolski1, T. LeRoith2, and A. Kemper3 University of Rochester, Rochester, NY, 2Virginia-Maryland College of Veterinary Medicine, Blacksburg, VA, 3Virginia Tech - Wake Forest University, Blacksburg, VA

1

2

K. Yates1, Y-C. Lu2, and C. Untaroiu2

P-Sat-50 Osseointegration of Wrapped Dental Implants in Rabbits 1

1

1 2

Michigan Technological University, Houghton, MI, 2Virginia Polytechnic and State University, Blacksburg, VA

1

A. Whitehead , S. Hyzy , D. Cohen , B. Boyan , , and Z. Schwartz , 1

P-Sat-70 Statistical Shape Analysis of the Human Spleen by Landmark Sliding

1 3

Virginia Commonwealth University, Richmond, VA, 2Georgia Institute of Technology, Atlanta, GA, 3University of Texas Health Science Center at San Antonio, San Antonio, TX

P-Sat-71 Relationship of Lumbar Angle and Torso Inclination in Adolescent Females

P-Sat-51 Characterization of Gold Nanoparticle Interactions with DNA Aptamers Studied through Absorbance and Fluorescent Spectroscopy

S. Galvis1, G. Baker1, S. Wilson1, and E. Friis1

1

J. Yoho1,2, J. Chavez2, N. Kelley-Loughnane2, and J. Hagen2 1

University of Dayton, Dayton, OH, 2Wright-Patterson Air Force Base, Dayton, OH

P-Sat-52 Drosophila melanogaster as a Simple Model to Test Dark Toxicity and Tolerance of Potential Photodynamic Therapy Agents J. Yoho1, C. Stroh1, S. Swavey1, and M. Kango-Singh1 University of Dayton, Dayton, OH

1

1

S. Rao1,2, J. Wang2, and A. Nain2 1

University of Virginia, Charlottesville, VA, 2Virginia Tech, Blacksburg, VA

P-Sat-73 A More Rigorous Swimming Regimen Does Not Enhance Cardiovascular Changes in Elastin-Deficient Mice D. Chirumbole1, K. Stoka1, and J. Wagenseil1

Biomechanics P-Sat-61 Analysis of Arterial Mechanics During Head-Down-Tilt Bed Rest M. Elliott1,2, D. Martin3, C. Westby2, M. Stenger3, and S. Platts4 Saint Louis University, Chattanooga, TN, 2Universities Space Research Association, Houston, TX, 3Wyle Science, Technology, and Engineering Group, Houston, TX, 4NASA Johnson Space Center Life Sciences, Houston, TX

1

P-Sat-62 Investigation of the Tibialis Posterior and Peroneus Longus Muscles on Foot Kinematics While Walking M. Bucklin and C. Neville

University of Kansas, Lawrence, KS

P-Sat-72 Single Cell Directionality on Suspended and Aligned Nanofibers

1

1

2

University of Rochester, Rochester, NY, 2Upstate Medical University, Syracuse, NY

1

Washington University in St. Louis, St. Louis, MO

P-Sat-74 Reduced arterial compliance decreases plaque development in Eln+/ApoE-/- mice S. Bhayani1, J. Maedeker2, K. Stoka2, and J. Wagenseil2 1

Saint Louis University, St. Louis, MO, 2Washington University in St. Louis, St. Louis, MO

P-Sat-75 Determining the Effect of Vimentin on Cell Traction Force and Stiffness A. Dagle1, G. Thomas2, and Q. Wen2 1

Clark University, Worcester, MA, 2Worcester Polytechnic Institute, Worcester, MA

P-Sat-76 In 2D and 3D In Vitro Vibrations Modulate Mesenchymal Stem Cell Proliferation and Enhance Gap Junction Intercellular Interaction with Osteoblast Like Bone Cells

Poster Session

P-Sat-64 Naive Endoscope Users Have Higher Forces on a Simulated Colon Model Compared to Experienced Endoscopist

R. Patel1, A. Damato1,2, S. Pongkitwitoon1, and S. Judex1

M. Farnham1, K. Bieryla1, E. Geist1, and D. Diehl2

P-Sat-78 Using Virtual Reality To Improve The Compliance Of Children And Adults To Daily Vibration Treatment While Measuring Treatment Efficacy

1

Bucknell University, Lewisburg, PA, 2Geisinger Health System, Danville, PA

P-Sat-65 Single-Level Cervical Fusion Does Not Increase Range of Motion in Adjacent Segments During Head Rotation T. West1, W. Anderst1, W. Donaldson1, J. Lee1, and J. Kang1 1

Undergraduate Research

Worcester Polytechnic Institute, Worcester, MA

P-Sat-67 Development of Pipette Aspiration Technique for Measurement of Chick Embryonic Myocardium Mechanical Properties

University of Pittsburgh, Pittsburgh, PA

P-Sat-66 Radiographic Evaluation of the Carpometacarpal Joint in Osteoarthritis Severity and Joint Laxity

Stony Brook University, Stony Brook, NY, 2Stony Brook University School of Medicine, Stony Brook, NY

1

S. Tikkireddy1, S. Lee1, A. Yang1, G. Pagnotti1, R. Tong2, C. Rubin1, and M. Chan1 Stony Brook University, Stony Brook, NY, 2The Hong Kong Polytechnic University, Hong Kong, China, People's Republic of

1

P-Sat-79 Initiation and Propagation of Microdamage in Cancellous Bone M. Luna1, A. Torres2, J. Matheny2, and C. Hernandez2 1

University of Arizona, Tucson, AZ, 2Cornell University, Ithaca, NY

S. Guang1, T. Patel1, and J. Crisco1 Brown University, Providence, RI

1

See page 194 for Poster floor plan

BMES 2014

197

Sat

saturday | october 25 | 2014

Poster Session Sat 9:30AM – 1:00pm   Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM

P-Sat-80 Measurement of Mechanical Tension Applied to the Nucleus of a Cell I. Ramachandran1, P. Arsenovic1, and D. Conway1 1

Virginia Commonwealth University, Richmond, VA

P-Sat-81 Uphill Walking Enhances The Retention Of A New Stepping Pattern Learned On A Split-Belt Treadmill J. Calvert1, C. Sombric1, and G. Torres-Oviedo1 1

University of Pittsburgh, Pittsburgh, PA

P-Sat-92 Measurement of Endoscopist Grip Strength and Manual Dexterity during a Day of Endoscopic Procedures M. Farnham1, Y. Melo1, Z. McCoy1, E. Geist1, K. Bieryla1, and D. Diehl2 1

Bucknell University, Lewisburg, PA, 2Geisinger Medical Center, Danville, PA

P-Sat-93 Investigation Of Psychophysical Testing Method For Vibrotactile Thresholds A. Perry 1 and R. Chapla1 1

North Carolina State University, Raleigh, NC

P-Sat-83 High Resolution, Low-Cost Transducer For Cellular Mechanics

P-Sat-94 Body Segment Parameters in Normal Weight Versus Obese Young Females

E. Richard1, N. Gambardella1, K. Kaspar1, and A. Valdevit 1

M. Knewtson1, Z. Merrill1, R. Cham1, and A. Chambers1

1

Stevens Institute of Technology, Hoboken, NJ

1

University of Pittsburgh, Pittsburgh, PA

P-Sat-84 Noninvasive Detection of Pain Associated Spinal Injuries In Vivo using microCT Imaging and Acoustic Emissions

P-Sat-95 Quantifying Tibiofemoral Joint Contact Forces in Patients with Knee Osteoarthritis Using OpenSim

A. Knight1, H. Cutcliffe1, G. Terziev1, C. Bass1, and J. Shridharani1

P. Kendell1 and S. Farrokhi1

1

Duke University, Durham, NC

1

University of Pittsburgh, Pittsburgh, PA

P-Sat-85 Hand Dominance and Physical Activity History Have Little Effect on Distal Radius Microstructure

P-Sat-96 Environmental and Storage Effects on Measurements of Porcine Lens Stiffness

O. Anjonrin-Ohu1, T. Butler2, J. Johnson2, and K. Troy2

B. Marchand1, S. Kumar1, and M. Reilly1

1

University of Tennessee, Kingsport, TN, 2Worcester Polytechnic Institute, Worcester, MA

1

University of Texas at San Antonio, San Antonio, TX

P-Sat-86 Microcontact-patterned Proteins on Cyclically Stretched Polyacrylamide Substrates

P-Sat-97 Mechanodifferentiation Of Progenitor Cells Cultured On An Intact ECM Scaffold

J. Uribe1, H. Cirka2, and K. Billiar2

C. Rabolli1, A. LeClair1, and C. Wagner1

University of Massachusetts Dartmouth, Dartmouth, MA, 2Worcester Polytechnic Institute, Worcester, MA

1

1

P-Sat-87 Characterization Of The Viscoelastic Property Of Mitral Valve Leaflets P. Parajuli1, S. Patnaik1, B. Brazile1, R. Prabhu1, H. Rhee1, L. Williams1, and J. Liao1 Mississippi State University, Mississippi State, MS

The College of New Jersey, Ewing, NJ

P-Sat-98 Methods for Patient-specific Aortic Dissection Modelling Z. Lucienne1, V. Flamini1, P. Ursomanno2, A. DeAnda2, and B. Griffith3 New York University Polytechnic School of Engineering, Brooklyn, NY, 2New York University School of Medicine, New York, NY, 3University of North Carolina at Chapel Hill, Chapel Hill, NC

1

1

P-Sat-88 Sex Differences in Proximal Pulmonary Artery Stiffness as Revealed by Exercise MRI.

J. Warczytowa1, O. Forouzan1, C. Francois1, O. Wieben1, and N. Chesler1 1 University of Wisconsin-Madison, Madison, WI

P-Sat-89 Correlation Between Acoustic Surface And Whole-Body Attenuations Using Reflection And Transmission QUS for Characteristic Of Bone Quality K. Agarwal1, L. Lin1, J. Muir1, and Y-X. Qin1 1

Poster Session

Sat

Stony Brook University, Stony Brook, NY

P-Sat-90 Mechanical and Cell-Matrix Cues that Induce EMT in a Mouse Lung Adenocarcinoma Model A. Lee1, R. Han2, and J. Grande-Allen2 1

Boston University, Boston, MA, 2Rice University, Houston, TX

P-Sat-91 Adapting Gait to Multifocal-Lens Glasses Improves Stepping Accuracy in Novice Wearers E. Weston1, B. Muncy2, D. Tomashek2, K. Keenan2, R. Smith2, and K. Beschorner1 University of Pittsburgh, Pittsburgh, PA, University of Wisconsin-Milwaukee, Milwaukee, WI

1

2

P-Sat-99 Quantifying Cell-Derived Strain In 3-Dimensional Self-Assembled Dogbone Microtissues B. Wilks1, J. Schell1, and J. Morgan1 1

Brown University, Providence, RI

P-Sat-100 Non-Invasive Characterization of Liver Stiffness Based on Tagged MRI and Inverse Finite Element Analysis F. Chaves Carvalho1, V. Flamini1, L. Axel2, S. Chung2, and S. Bhagavatula2 New York University Polytechnic School of Engineering, New York, NY, 2New York University Langone Medical Center, New York, NY

1

P-Sat-101 High Resolution Particle-Tracking Microrheology In Endothelial Cells And Glycocalyx Layer P. Yu1, Y-L. Liu1, A. Hsu1, P. Voyvodic1, A. Baker1, and H-C. Yeh1 1

University of Texas at Austin, Austin, TX

P-Sat-102 The Collagen Microstructure in the Peripapillary Sclera of the Optic Nerve Head S. Moed1, N-J. Jan1, S. Smelko1, R. O'Malley1, A. Dees1, J. Constantin1, M. Urich1, M. Iasella1, N. Rutowski1, T. Martin1, C. Gomez1, H. Tran1, J. Grimm1, K. Lathrop1, and I. Sigal 1 University of Pittsburgh, Pittsburgh, PA

1

P-Sat-103 Lower Extremity Pediatric Orthotic Gait Trainer Lower Extremity Gait Trainer M. Yin1, B. McDeed2, A. Galczynski2, and T. Le1 P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

198

BMES 2014

Mercer University, Macon, GA, 2Mercer University, MAcon, GA

1

9:30AM – 1:00pm Poster Session Sat

2014 | october 25 | Saturday

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am P-Sat-103 Development of a Finite Element Model of the Gottingen Minipig Head to Investigate Complex Impact Scenarios

P-Sat-117 Detection of Giardia lamblia Cysts and Cryptosporidium parvum Oocysts Using Digital Image Processing

W. Baker1, E. Fievisohn1, P. VandeVorde1, C. Untaroiu1, and W. Hardy1

A. Gifford1, H. Ceylan Kodemir1, and A. Ozcan1

1

1

P-Sat-104 Design And Testing Of Composite Materials For Use In The Outer Shell Of Contact Sport Helmets N. Walters1, N. Patzin1, D. Barry1, G. Batt1, and J. Desjardins1 1

University of California Los Angeles, Los Angeles, CA

P-Sat-118 Using Targeted Molecular Imaging For In Vivo Evaluation Of DoxorubicinBased Anti-Cancer Treatment In Combination With The Herbal Medicine Black Cohosh In MCF-7 Xenografts S. Schuh1,2, M. Wozniak1,3, J. Hedhli1,2, S. Slania1,2, A. Czerwinski4, L. Kalinowski1,3, L. Dobrucki1,2, and I. Dobrucki1

Clemson University, Clemson, SC

Beckman Institute for Advanced Science and Technology, Urbana, IL, 2Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, 3Department of Medical Laboratory Diagnostics, Medical University of Gdansk, Gdansk, Poland, 4Peptides International Inc., Louisville, KY 1

Biomedical Imaging and Optics P-Sat-108 Assessing Edge-Thickness of Soft Contact Lenses Using Gabor-Domain Optical Coherence Microscopy

P-Sat-119 Vesicular Localization Induced by Dextran Uptake

J. Won1, P. Tankam1, I. Cox1, and J. Rolland1

1

1

University of Rochester, Rochester, NY

T. Netterfield1, M. Kemp1, C. Payne1, and S. Sarkar2 Georgia Institute of Technology, Atlanta, GA, 2Northeastern Univeristy, Boston, MA

P-Sat-109 Evaluation of an Infrared Imager for Breast Cancer Screening

P-Sat-120 Single-Nucleotide Polymorphism (SNP) Detection Using a DNA-based Machine

S. Tirumala1 and M. Loew1

M. Fan1, K. Yehl1, and K. Salaita1

1

George Washington University, Washington, DC

1

Emory University, Atlanta, GA

P-Sat-110 Color Coding Optically Sectioned Fresh Biopsies for Rapid Pathological Assessment

P-Sat-121 Diffuse Correlation Spectroscopy to Monitor Longitudinal Vascular Changes in Murine Allografts with Tissue-Engineered Periosteum

J. Juan1, N. Loewke2, S. Sensarn2, S. Rogalla2, D. Rimm3, and C. Contag2

E. Mannoh1, S. Han2, M. Hoffman1, M-J. Beltejar1, D. Benoit1, and R. Choe1

1

Brown University, Providence, RI, 2Stanford University, Stanford, CA, 3Yale University, New Haven, CT

1

P-Sat-111 Evaluation of the Targeting Ability of Chain-Like Nanoparticles Towards Micrometastasis

P-Sat-122 Optimizing Imaging and Computational Analysis for 3D Topographical Visualization of Optically Cleared Whole Normal and Regenerative Tissues

G. Doron1, A. Goldberg1, P. Peiris1, E. Doolittle1, R. Toy1, and E. Karathanasis1

K. Cowdrick1,2, K. Nelson1,3, G. Christ1, and F. Marini1,4

Case Western Reserve University, Cleveland, OH

1

Department of Biomedical Engineering, University of Rochester, Rochester, NY, 2Institute of Optics, University of Rochester, Rochester, NY

Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, 2University of Notre Dame, South Bend, IN, 3Wake Forest School of Medicine, Winston-Salem, NC, 4Wake Forest University Baptist Medical Center, Winston-Salem, NC

1

P-Sat-112 Phase Microscopy of Endothelial Cell Interactions in Scattering Media with Oblique Back-Illumination 1

P-Sat-123 Quantitative Analysis of Conceptual Pattern Recognition Tasks under Ambiguous Conditions

3

M. Wenke1, E. Lin1, P. Shah1, J. Ide1, and L. Mujica-Parodi1

A. Anderson1, T. Ford2, and G. Tearney2,3 University of Rochester, Rochester, NY, 2Massachusetts General Hospital, Boston, MA, Harvard Medical School, Boston, MA

1

P-Sat-113 Quantifying Cell Surface Receptor Expression In Live Tissue Culture Media Using Dual-Tracer Approach A. Singh1, X. Xiaochun Xu1, L. Sinha1, C. Yang1, J. Xiang1, and K. Tichauer1 1

State University of New York at Stony Brook, Stony Brook, NY

P-Sat-124 Kinetic Modeling of Fluorescent Uptake in the Retina for Blood Flow Mapping L. Hones1, M. Guthrie1, L. Sinha1, J. Kang-Mieler1, and K. Tichauer1

Illinois Institute of Technology, Chicago, IL

1

P-Sat-114 Computer Simulation of Tooth Mobility Using Varying Material Properties A. Beckmann1, S. Raith2, L. Unterberg2, and H. Fischer2 Virginia Commonwealth University, Richmond, VA, 2RWTH Aachen University, Aachen, Germany

1

P-Sat-115 Non-linear Optical Microscopy of Murine Abdominal Aortic Aneurysm K. Wilson1, A. Yrineo2, A. Adelsperger2, H. Schroeder2, D. Zhang2, J. Zhang2, C-S. Liao2, F. Damen2, E. Phillips2, J-X. Cheng2, and C. Goergen2 1

University of Arkansas, Fayetteville, AR, 2Purdue University, West Lafayette, IN

P-Sat-116 Design and Optimization of a Hyperspectral Illumination Source for Clinical and Preclinical Imaging

Illinois Institute of Technology, Chicago, IL

P-Sat-125 Axonal Water Fraction is Related to Head Impact Exposure in High School Varsity Football Players K. Apkarian1,2, E. Davenport2, J. Urban2, M. Espeland2, C. Whitlow2, Y. Jung2, D. Rosenbaum2, A. Powers2, J. Stitzel2, and J. Maldjian2 The Johns Hopkins University, Baltimore, MD, 2Wake Forest School of Medicine, WinstonSalem, NC

1

P-Sat-126 PET-CT Imaging of Peripheral Angiogenesis in Type-1 Diabetes Using Novel Dimeric cRGD Peptide S. Slania1,2, A. Czerwinski3, I. Dobrucki2, and L. Dobrucki1,2 University of Illinois at Urbana-Champaign, Urbana, IL, 2Beckman Institute for Advanced Science and Technology, Urbana, IL, 3Peptides International Inc., Louisville, KY

1

A. Arshad1, S. Mayes1, T. Rich1, and S. Leavesley1 1

Undergraduate Research

Virginia Polytechnic Institute and State University, Blacksburg, VA

University of South Alabama, Mobile, AL

See page 194 for Poster floor plan

BMES 2014

199

Poster Session

Sat

Poster Session Sat 9:30AM – 1:00pm

saturday | october 25 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM P-Sat-127 Ultrasound Characterization Of The Tibialis Anterior Muscle In Children With Cerebral Palsy And Foot Drop.

P-Sat-140 Improving the Response Post-Adoptive Cell Transfer of Dendritic Cells Using Microfluidic Delivery

A. Aralar1, D. Turo1, A. Eranki1, C. Stanley2, D. Damiano2, and S. Sikdar1

S. Liu1,2

1

George Mason University, Fairfax, VA, 2National Institutes of Health, Bethesda, MD

P-Sat-128 A Novel SNR Measure for Estimation of Shear Stiffness in MR Elastography K. Huynh1, R. Eon2, D. Lake3, and A. Manduca3 1 The University of Texas at Austin, Austin, TX, 2Viterbo University, La Crosse, WI, 3Mayo Clinic, Rochester, MN

P-Sat-129 Highly Sensitive Label-free Biosensors Based On Biconically Tapered Fibers C. Rowland1 1

K. Hemzacek , R. Shankar , K. Hussain , and V. Kodibagkar 1

1

P-Sat-141 Strain Visualization And Quantification For Abdominal Aortic Aneurysm Rupture Risk Prediction 1

P-Sat-130 Development of a Temperature Sensitive MRI Contrast Agent 1

Cardiovascular Engineering

L. Yang1, N. Couper1, D. Mix1, M. Richards1, and A. Chandra1

California State Polytechnic University, Pomona, Los Angeles, CA

1

Massachusetts Institute of Technology, Cambridge, MA, 2David H. Koch Institute of Integrative Cancer Research, Cambridge, MA

1

1

Arizona State University, Tempe, AZ

University of Rochester, Rochester, NY

P-Sat-142 Ex Vivo Assessment Of A Novel Inflow Cannula For Pediatric ContinuousFlow Ventricular Assist Devices M. Griffin1,2, M. Grzywinski1,2, S. Olia1,2, and M. Kameneva1,2,3 Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, 2McGowan Institute for Regenerative Medicine, Pittsburgh, PA, 3Department of Surgery, University of Pittsburgh, Pittsburgh, PA 1

Cancer Technologies P-Sat-132 A Caspase-8 Reporter Cell Line from Non-Small Cell Lung Cancer for AntiCancer Drug Screening H. Lee , Z. Dereli-Korkut , L. Yang , and S. Wang 1

1

1

1

The City College of New York, CUNY, New York, NY

A. Valiga1, D. Widmer1, T. Biedermann2, P. Cheng1, R. Dummer1, and M. Levesque1 University Hospital Zürich, Zürich, Switzerland, 2University Children's Hospital Zürich, Zürich, Switzerland

1

P-Sat-135 Polyvalent Aptamers for the Enhanced Capture of Circulating Tumor Cells in Dynamic Conditions G. Gydush1, E. Richards1, and Y. Wang*1

S. Nolan1, L. Barney1, and S. Peyton1 University of Massachusetts Amherst, Amherst, MA

P-Sat-137 Understanding Glioblastoma Migration on Engineered Aligned Nanofibers

Sat

S. Arora1, A. Beliveau2, and A. Jain2 1

Johns Hopkins University, Baltimore, MD, 2Worcester Polytechnic Institute, Worcester, MA

P-Sat-138 ECM Stiffening Drives EMT-Like Changes in 3D Epithelial Cell Morphogenesis K. Martin1, S. Carey1, and C. Reinhart-King1 1

Cornell University, Ithaca, NY

P-Sat-139 Varying Concentrations Of Thrombin Affects Tumor Cell Adhesion In Dynamic Conditions D. Lee , G. Gydush , E. Richards , Y. Wang , and C. Dong 1

2

2

2

2

The Pennsylvania State University, State College, PA, 2The Pennsylvania State University, University Park, PA

1

W. Zhang1 and J. Holmes1 1

University of Virginia, Charlottesville, VA

P-Sat-145 Graphical User Interface To Quantify In Vitro Cardiomyocyte Contractility K. McCarty1, I. Rivera2, and C. Simmons2 1

Rice University, Houston, TX, 2University of Florida, Gainesville, FL

P-Sat-146 Experimental and Computational Models of Microparticle Transport under Dynamic Flow Conditions C. DeZerga1, J. Gonzaga2, and C. Hall3

The Pennsylvania State University, State College, PA

P-Sat-136 Integrin-Mediated Metastatic Plasticity in Breast Cancer

Poster Session

Bucknell University, Lewisburg, PA, 2Geisinger Health System, Danville, PA

P-Sat-144 The Role of Reflex Compensation Following Myocardial Infarction: Supplementing Reported Data Through Model-Based Optimization.

Moved to P-Sat-52.

1

M. Lewis1, C. Buffinton1, and R. Mangano2 1

1

P-Sat-134 Development of a Screening Array for Congenital Melanocytic Nevi

1

P-Sat-143 3D Reconstruction and Printing of CHD Hearts from Medical CT and Amira Software

The College of New Jersey, Freehold, NJ, 2The College of New Jersey, Clifton, NJ, 3The College of New Jersey, Ewing, NJ

1

P-Sat-147 Analysis Of A Medical-grade Material Used In A Cardiac Device K. Brown1, A. Adkins2, E. Hord3, C. Bolch4, and J. Criscione3 1 3

Mississippi State University, Mississippi State, MS, 2St. Mary's University, San Antonio, TX, Texas A&M University, College Station, TX, 4CorInnova Incorporated, College Station, TX

P-Sat-148 Durability of a Device Designed for Cardiac Assist and Support in a Failing Heart A. Adkins1, K. Brown2, E. Hord3, C. Bolch4, and J. Criscione3,4 1 3

St. Mary's University, San Antonio, TX, 2Mississippi State University, Mississippi State, MS, Texas A&M University, College Station, TX, 4CorInnova Inc., College Station, TX

P-Sat-149 Biophysical Mechanisms Underlying Increased Cardiac Contraction by Myofilament Acetylation Y. Wang1, S-H. Smith1, and S-G. Shroff1 1

University of Pittsburgh, Pittsburgh, PA

P-Sat-150 The Role of Heparanase in a Diabetic Mouse Model S. Mahajan1, G. Singh1, E. Nunez1, S. Das1, and A. Baker1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

200

BMES 2014

University of Texas at Austin, Austin, TX

9:30AM – 1:00pm Poster Session Sat

2014 | october 25 | Saturday

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am P-Sat-151 Adeno-associated Virus Mediated Gene Delivery in Rat Cardiomyocytes G. Sadananda1, C. Ambrosi1, and E. Entcheva1 1

L. Suchomel1, S. Eyerly2, and P. Wolf1

Stony Brook University (SUNY), Stony Brook, NY

D. Pedersen1, M. Jamiolkowski1, M. Kameneva1, J. Antaki1,2, and W. Wagner1 University of Pittsburgh, Pittsburgh, PA, 2Carnegie Mellon University, Pittsburgh, PA

P-Sat-153 Effect of C-Kit And KDR Stem Cell Markers on PDGFR-a in a Diabetic Mouse Myocardium S. Ilbeig1, G. Singh1, S. Das1, and A. Baker1 1

The University of Texas at Austin, Austin, TX

P-Sat-154 Development of an Automatic System for the Acquisition of ARFI Ultrasound Images during Diastole K. Kessinger1, S. Eyerly1, and P. Wolf1 1

1

P-Sat-164 Baseline Relation Of Asymmetric Dimethylarginine (ADMA) Levels And Whole Blood Viscosity (WBV) In Patients With End Stage Renal Disease R. Trigalo1, R. Madhuraoantula2, A. Singh2, M. Hammes3, and P. Dhar2 University of Illinois at Urbana-Champaign, Champaign, IL, 2Illinois Institute of Technology, Chicago, IL, 3University of Chicago, Chicago, IL

1

P-Sat-165 Effect of Exogenous TGFβ and its Inhibitors on Hyaluronan Homeostasis in Porcine Aortic Valve Interstitial Cells A. Stout1, V. Krishnamurthy1, and K. Grande-Allen1 1

Rice University, Houston, TX

P-Sat-166 Characterizing Mechanical Properties of Cardiac Microtissues E. Robinson1, A. Desai1, J. Rodriguez-Devora1, and D. Dean1

Duke University, Durham, NC

1

P-Sat-155 Regional Strain Quantification of Induced Pluripotent Derived Cardiomyocytes Cultured on a Stiff Substrate E. Clark1, R. Orr2, J. Favreau2, and G. Gaudette2 1

Duke University, Durham, NC, 2Duke University, Durh, NC

Rice University, Houston, TX, 2Worcester Polytechnic Institute, Worcester, MA

P-Sat-156 Investigating The Effect Of 5-hydroxytryptamine On The Functional Properties Of The Cardiac Valve

Clemson University, Clemson, SC

Undergraduate Research

P-Sat-152 Real-Time Visualization of Platelet Deposition Onto Ti6Al4V in Disturbed Flow Geometries 1

P-Sat-163 Visualization of Convective Heat Transfer with a Thermal Camera In Vivo During Cardiac Radiofrequency Ablation

Biomedical Engineering Education P-Sat-170 Analyzing the Diffusion of Water in Ion-Exchange Gels Using NMR Methods J. Feindt1 and J. Maneval1 1

Bucknell University, Lewisburg, PA

R. Reynolds1, A. Razavi1, C. Martindale1, J. Morales1, and K. Balachandran1 1

University of Arkansas, Fayetteville, AR

P-Sat-157 In Vitro Bioactivity Testing of Cardiac Derived Extracellular Matrix Using Stem Cells T. Grubb1 and G. Zhang1 1

The University of Akron, Akron, OH

P-Sat-158 In Vitro and Ex Vivo Substrate Stiffness Effects on Endothelial Permeability in Response to TNFα C. Furia1, R. Lownes Urbano1, P. Osei-Owusu1, and A. Morss Clyne1 1

Drexel University, Philadelphia, PA

P-Sat-159 Development of a Valve-on-Chip to Study Cardiac Valve EndothelialMesenchymal Transformation J. Carradini1, N. Sturdivant1, and K. Balachandran1 1

P-Sat-171 Endothelial Surface Glycocalyx Stimulation Induced Nitric Oxide and Calcium Signaling D. Chester1, M. Dragovich1, B. Fu2, and X. Zhang1 Lehigh University, Bethlehem, PA, 2The City College of The City University of New York, New York City, NY

1

P-Sat-172 Endovascular Coil Geometry Determines Blood Clot Permeability E. Nagel1, B. Earnest1, A. Evans1, and B. Helmke1 1

University of Virginia, Charlottesville, VA

P-Sat-173 Effects of an Aquaporin Inhibitor on Cryosurgery of Breast Cancer Cells H. Reavis1, D. Dréau2, and C. Lee2

University of Arkansas, Fayetteville, AR

P-Sat-160 Analysis of Structural Changes in Developing Hearts Due to Hyperglycemia M. Caruso1, T. Lawson2, and M. Hinds2 1 Washington State University, Pullman, WA, 2OHSU, Portland, OR

P-Sat-161 Influence of Ionic Strength and pH on Neonatal Clot Structure K. Ahlstedt1, A. Brown1, S. Saxena1, N. Welsch1, J. Fernandez2, N. Guzzetta2,3, and T. Barker1,4 Georgia Tech, Atlanta, GA, 2Childrens Healthcare of Atlanta, Atlanta, GA, 3Emory University, Atlanta, GA, 4Emory University School of Medicine, Atlanta, GA

1

P-Sat-162 Parametric Anatomical Models: Rapid Prototyping Methods and Approaches M. Allain1, M. Le Saout2, and C. Taylor1 1

Cellular and Molecular Bioengineering

University of Louisiana at Lafayette, Lafayette, LA, University of Poitiers, Poitiers, France 2

1 University of North Carolina at Chapel Hill, Chapel Hill, NC, 2University of North Carolina at Charlotte, Charlotte, NC

Poster Session

P-Sat-174 Rapid Characterization of G-quadruplexes in Double-Stranded DNA

Sat

J. Sanoica1, J. Calvert1, A. Kreig1, R. Tipanna1, and S. Myong1 1

University of Illinois at Urbana-Champaign, Champaign, IL

P-Sat-175 Analysis of Shear-Induced Calcium Oscillations in Vascular Endothelium J. Julian1,2, C. Scheitlin1,2, and B. Alevriadou1,2 The Ohio State University, Columbus, OH, 2Davis Heart & Lung Research Institute, Columbus, OH

1

P-Sat-176 Mapping Sensory Diversity Using High-throughput Neural Imaging in C. elegans T. Gongs1, R. Lagoy2, and D. Albrecht2 Louisiana State University, Baton Rouge, LA, 2Worcester Polytechnic Institute, Worcester, MA

1

See page 194 for Poster floor plan

BMES 2014

201

Poster Session Sat 9:30AM – 1:00pm

saturday | october 25 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM P-Sat-177 Lysyl Oxidase Inhibitor β aminopropionitrile Reduces Invasiveness of Male Mammary Tumor Cells

P-Sat-189 Application of Interfacial Shear Stress to Annulus Fibrosus Cells

K. Young1, A. Abraham1, A. Brock1, and R. Ho1

1

1

The University of Texas, Austin, TX

P-Sat-179 Clinical and Molecular Expression Profiles Revealed Abnormal Plasma mir22 in Patients with Aortic Valve Stenosis

A. Uppala1, S. Han1, and A. Hsieh1 University of Maryland College Park, College Park, MD

P-Sat-190 Effect of Chitosan's Biochemical Properties on Antimicrobial Activity A. Tabassum1, B. Koppolu1, and D. Zaharoff1 1

University of Arkansas, Fayetteville, AR

M. Bange1, S. Samy2, M. Shuler1, and M. Ariza-Nieto1 1

Cornell University, Ithaca, NY, 2Guthrie Clinic, Sayre, PA

Device Technologies and Biomedical Robotics

P-Sat-180 Amplifying Signals From Riboswitch Biosensors A. Bennett1,2, M. Goodson2, and N. Kelly-Loughnane2 1

The University of Dayton, Dayton, OH, 2711th Human Performance Wing, Dayton, OH

P-Sat-181 In vitro Endothelialized Microfluidic Assay to Study Pulmonary Vasoocclusion in Sickle Cell Disease A. Moore , , P. Sundd , , , E. Gutierrez , and A. Groisman 1 2

1 2 3

4

4

University of Pittsburgh, Pittsburgh, PA, 2Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh-School of Medicine, Pittsburgh, PA, 3Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh-School of Medicine, Pittsburgh, PA, 4Department of Physics, University of California-San Diego, La Jolla, CA 1

P-Sat-182 Engineering The Extracellular Matrix Of Probiotic Bacteria To Control Localized Adhesion In The Gut T. Nash1,2, F. Ward1,2, P. Praveschotinunt1,2, A. Duraj-Thatte1,2, and N. Joshi 1,2 Harvard University, Cambridge, MA, 2Wyss Institute for Biologically Inspired Engineering, Boston, MA

1

P-Sat-183 Characterizing Thermodynamic Constraints of T4 Lysozyme Secretion via the Type III Secretion System C. Li1, A. Azam1, and D. Tullman-Ercek2 College of Engineering, UC Berkeley, Berkeley, CA, 2College of Chemistry, UC Berkeley, Berkeley, CA

1

P-Sat-184 Expression Profiles of Extracellular Vesicle CD14 in Liver Tissue and Plasma in Patients Undergoing Roux-en-Y Gastric Bypass M. Bange1, J. Alley2, M. Shuler1, and M. Ariza-Nieto1 1

Cornell University, Ithaca, NY, 2Guthrie Clinic, Sayre, PA

P-Sat-185 Modeling Tumor-Macrophage Interactions In 3D Micro-Tissues A. Rodriguez1, A. Brock1, and H. Joyce1 1

The University of Texas at Austin, Austin, TX

P-Sat-186 Proliferation of Aging Human Cord Blood-Derived Endothelial Cells on Variably Compliant Polyacrylamide Gels S. Bowman , , T. Cheung , J. Fu , and G. Truskey 1 2

Poster Session

Sat

1

2

2

2

Vanderbilt University, Nashville, TN, 2Duke University, Durham, NC

P-Sat-187 The Use Of Ga(III) and Zn(II) Hemecomplexes As A Novel Strategy For Treatment of Staphylococcus aureus Biofilms A. Albach1,2 US Army Institute of Surgical Research, Ft. Sam Houston, TX, 2St. Mary's Univeristy, San Antonio, TX

1

P-Sat-188 Structural Determination of an Avian Astrovirus Capsid Core Structural Determination of an Avian Astrovirus Capsid Core R. York1 and R. DuBois1 1

Univeristy of California Santa Cruz, Santa Cruz, CA

P-Sat-195 An ECG-Embedded Weight Scale for the Measurement of the QTc Interval in Healthy Adult Individuals X. Niu1 and J-P. Couderc1 1

University of Rochester, Rochester, NY

P-Sat-197 Neonatal Temperature Sensor for the Developing World M. Yamagami1, E. Silva1, H. Chen1, E. Alexander1, K. Maynard1, P. Keahey1, Q. Dube2, and R. Richards-Kortum1 1

Rice University, Houston, TX, 2Queen Elizabeth Central Hospital, Blantyre, Malawi

P-Sat-198 Firefighter Health Monitoring Using Wearable EKG Sensors with Bioidentification Capability J. Farmer1 and J. Yao1 1

East Carolina University, Greenville, NC

P-Sat-199 An Implantable Pneumatic Driver With Non-Invasive Transmural Powering For Cardiac Assist Devices S. Razvi1,2, S. Zambrano1, J. Coello3, J. Criscione1, and M. Moreno1 1 3

Texas A&M University, College Station, TX, 2The University of Texas at Austin, Austin, TX, Instituto Tecnológico de Mérida, Yucatán, Mexico

P-Sat-200 Debubbling Rotary Planar Peristaltic Micropump S. Rice1, R. Reiserer1, D. Markov1, S. Sherrod1, E. Werner1, K. Seale1, and C. Marasco 1 1

Vanderbilt University, Nashville, TN

P-Sat-201 Development of an Analog Front End for the AD5933 Impedance Analyzer to Make Accurate Bio-Impedance Measurements for a Brain on a Chip Device S. Halim1, O. Hoilett1, J. Kribb1, R. Reiserer1, and J. Wikswo1 1

Vanderbilt University, Nashville, TN

P-Sat-202 Electronic Platform For Automatic Short Performance Physical Battery (SPPB) Test Y. Bai1, N. Marco1, W. Jia1, H. Zhang2, Z-H. Mao1, J. Zgibor1, L. Burke1, S. Albert1, A. Newman1, and M. Sun1 University of Pittsburgh, Pittsburgh, PA, 2Beihang University, Beijing, China, People's Republic of

1

P-Sat-203 Pressure-sensing Pads for Ultrasound Tissue Mechanics Characterization C. Corbett1, K. Showers1, H. Scruggs1, E. Kowal1, C. Kerr1, H. Cash1, M. Hanschke1, D. Dean1, and D. Kwartowitz1 1

Clemson University, Clemson, SC

P-Sat-204 A Method for Determining Skull Coupling of an Instrumented Mouthguard Using Stereo Vision K. Bui1 and B. Hammoor1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

202

BMES 2014

1

Stanford University, Stanford, CA

9:30AM – 1:00pm Poster Session Sat

2014 | october 25 | Saturday

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am P-Sat-205 Optimizing Fat Delivery Methods in Continuous Enteral Feeding of Expressed Breast Milk to Neonates

P-Sat-218 Synthesis and Characterization of Magnetic Nanoparticles for Drug Delivery to Central Nervous System

K. Abdelrahman1,2, A. Hair2, K. Hawthorne2, and S. Abrams2

L. Bruk1, N. Snyder1, X. Cui1, Y. Zhao1, and T. Ibrahim1

1

1

University of Pittsburgh, Pittsburgh, PA

P-Sat-206 Upper Extremity Frailty Assessment in Trauma Patients Using Wearable Sensor Technology

P-Sat-219 Engineering of Liposomal Nanoparticles as a Platform for Advanced Drug Delivery Applications

M. Heusser1, N. Toosizadeh1, B. Zangbar-Sabegh1, J. Mohler1, B. Joseph1, and B. Najafi1

D. Francis1, P. Kholmatov1, S. Hayward1, and S. Kidambi1

1

University of Arizona Medical Center, Tucson, AZ

P-Sat-207 Finite Element Analysis Comparison of Two Types of Removable Partial Denture Designs L. Petku1, E. Meyer1, and J. Knapp2 1

1

P-Sat-220 Effect of Nanoparticle Morphology and Surface Modification on Tumor Penetration and Distribution L. Sims1, H. Frieboes1, and J. Steinbach1 1

Lawrence Technological University, Southfield, MI, 2University of Michigan, Ann Arbor, MI

P-Sat-208 An Automated Fast-ELISA System for the Quantitative Detection of Biomarkers In Vitro D. Maxim1,2 and I. Georgakoudi2

Drug Delivery

P-Sat-221 A Sweet Nano-affair of Carbon Particles with Deoxyribose Nucleic Acid for Gene Therapy A. Ohoka1,2, S. Misra1,2,3, and D. Pan1,2,3 University of Illinois at Urbana-Champaign, Champaign, IL, 2Biomedical Research Center and Carle Foundation Hospital, Urbana, IL, 3Beckman Institute, Urbana, IL

P-Sat-222 Effects Of Industrially Processed PLGA Thin Films On Drug Delivery and Material Properties D. Horne1, Y. Zhou2, K. Vedantham2, and T. Steele2 1

P-Sat-211 Cross-linked Lipid Particles for Delivery of Antiretroviral Combinations to Inhibit HIV-1 Infection W. Lykins1, R. Ramanathan1, Y. Jiang1, and K. Woodrow1

P-Sat-223 Optimization of Parameters Influencing Polyethylene Glycol Microsphere Fabrication Using Electrospraying 1

S. Srinivasan1, H. Mannam2, Q. Song2, C. Mirkin2, and A. Paller2 Case Western Reserve University, Cleveland, OH, 2Northwestern University, Chicago, IL

J. Nam1, E. Rivera1, and H. von Recum1

E. Lowry1, C. Wallace1, B. Koppolu1, S. Smith1, and D. Zaharoff1 University of Arkansas, Fayetteville, AR

P-Sat-225 A Novel Approach For Root Canal Treatment: Encapsulation of Oral Antibiotics For Drug Delivery Into Dentin Tubules R. Haseeb1, M. Lau1, L. Rodriguez1, M. Stefan1, K. Palmer1, F. Montagner2, and D. Rodrigues1

Case Western Reserve University, Cleveland, OH

P-Sat-214 Transgene Induction from Cyclodextrin Based Polymers

University of Texas at Dallas, Richardson, TX, 2Federal University of Rio Grande do Sul, Porto Alegre, Brazil

1

E. Ward1, E. Rivera-Delgado1, and H. von Recum1 1

Saint Louis University, St. Louis, MO

P-Sat-224 Novel Chitosan-based Hydrogel for Controlled Release of Anti-tumor Cytokines 1

P-Sat-213 Dual Drug Release of Doxorubicin and 2-Methoxyestradiol to Inhibit Cancer Cell Invasion and Proliferation 1

Clemson University, Clemson, SC, 2Nanyang Technological University, Singapore, Singapore

K. Scott1, E. Jain1, S. Zustiak1, and S. Sell1

University of Washington, Seattle, WA

P-Sat-212 Targeting Human Epidermal Hyperplasia by Suppressing Human HRAS Through Spherical Nucleic Acid (SNA) Nanoconjugates 1

University of Louisville, Louisville, KY

1

Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Tufts University, Medford, MA

1

1

University of Nebraska-Lincoln, Lincoln, NE

P-Sat-226 Role of Membrane Rafts in Nanoparticle Uptake by Endothelial Cells

Case Western Reserve University, Cleveland, OH

P-Sat-215 Multivalent Presentation of HER2 Epitopes on Filamentous Plant Virus Platform: A Potential Breast Cancer Vaccine N. DiFranco1, S. Shukla1, U. Commandeur2, and N. Steinmetz1 Case Western Reserve University, Cleveland, OH, 2RWTH Aachen University, Aachen, Germany

1

P-Sat-216 TMV Formulation for Imaging and Targeted Treatment of Thrombosis G. Hsu1, A. Wen1, Y. Wang 2, K. Jiang1, A. Yang1, H. Gao2, X. Yu1, D. Simon2, and N. Steinmetz 1,2 Case Western Reserve University, Cleveland, OH, 2Case Cardiovascular Research Institute, Cleveland, OH

1

P-Sat-217 Estimating the Controlled Release of PRP Components Encapsulated in Biodegradable PEG Hydrogels

M. Bland1, S. Son2, and P. Butler2 1

University of Alabama, Birmingham, AL, 2Penn State University, University Park, PA

P-Sat-227 The Characterization of PEG-based Hydrogels for Application in Ocular Drug Delivery E. Canning , E. Dosmar , and J. Kang-Mieler 1

1

2

2

Saint Louis University, St. Louis, MO, 2Illinois Institute of Technology, Chicago, IL

P-Sat-228 Controlled Self-Assembly and Dynamics of Nanoscale Bacteria-Enabled Autonomous Drug Delivery Systems (NanoBEADS) C. Damico1, M. Traore1,2, and B. Behkam1 Virginia Polytechnic and State University, Blacksburg, VA, 2Washington University, St. Louis, MO

1

S. Sheth1, E. Jain1, S. Sell1, and S. Zustiak1 1

Undergraduate Research

University of Pittsburgh, Pittsburgh, PA, 2Baylor College of Medicine, Houston, TX

Saint Louis University, St Louis, MO

See page 194 for Poster floor plan

BMES 2014

203

Poster Session

Sat

Poster Session Sat 9:30AM – 1:00pm

saturday | october 25 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM P-Sat-229 Regional Nanoparticle Delivery in the Central Nervous System as a Function of Route of Administration

P-Sat-249 Cellular Deformation Via Varying Geometric Channels And Dynamic Flow Resistance

E. Chung1,2, A. Prakapenka1,2, D. DiPerna1, R. McCall1, and R. Sirianni1,2

J. Vavra1, J. Zheng1, and J. Zahn1

Barrow Neurological Institute, Phoenix, AZ, 2Arizona State University, Tempe, AZ

1

1

P-Sat-250 Optical Imaging of Biomolecular Tension with Sub-100 nm Resolution

Nano to Micro Technologies

R. Park1, Y. Liu2, and K. Salaita2 1

P-Sat-239 Experimental Optical Properties Of Quadruplex DNA K. Krawiec , K. Lee , D. Dryden , Y. Ma , R. French , N. Steinmetz , L. Poudel , W-Y. Ching2, R. Podgornik3, and V. Parsegian3 1

1

1

1

1

1

2

P-Sat-251 Testing the Effect of Red Blood Cell Shape on Perfusion of a Microvascular Network P. Pourreau1, N. Piety1, and S. Shevkoplyas1

P-Sat-240 Dual-gel Construct with Dynamic Control of Soluble Chemotactic Cues for the Study of Neural Cells

P-Sat-252 The Effects of Nanoparticle Ingestion on Glucose Transport and Uptake in the Gut Microbiome

O. Kuzura1,2, C. Petersen1,3, V. Rengarajan1, and R. Perez-Castillejos1

G. Shull1, J. Richter1, J. Fountain1, G. Mahler1, and A. Fiumera1

New Jersey Institute of Technology, Newark, NJ, 2Grinnell College, Grinnell, IA, 3Case Western University, Cleveland, OH

1

1

P-Sat-241 Application of Switchable Silicon Nanomembranes for Controlled Therapeutic Release S. Wayson1, G. Madejski1, K. Smith1, and J. McGrath1 1

University of Rochester, Rochester, NY

P-Sat-242 High Yielding Conversion of Modified Tobacco Mosaic Virus to Functional Spherical Nanoparticles Using a Mesofluidic Device A. VanMeter1, M. Bruckman1, and N. Steinmetz1 Case Western Reserve University, Cleveland, OH

1

P-Sat-243 Fabrication of a Porous Matrix Integrated into Microfludic Devices for HIV Capture K. Kundrod1, K. Surawathanawises1, and X. Cheng1 Lehigh University, Bethlehem, PA

1

P-Sat-244 The Effect of Chondroitin Sulfate Proteoglycan Surface Gradient Profile on Neurite Growth A. Geldert ,

1 2

National Institutes of Health, Bethesda, MD, 2University of Virginia, Charlottesville, VA

1

P-Sat-245 Paper-Based Capture of Neisseria gonorrheae for Point-of-Care Diagnostics C. Ellenson1, J. Linnes1, and C. Klapperich1 Boston University, Boston, MA

1

Sat

Brown University, Providence, RI, 2Emory University, Atlanta, GA

Case Western Reserve University, Cleveland, OH, 2University of Missouri-Kansas City, Kansas City, MO, 3University of Massachusetts, Amherst, MA

1

Poster Session

Rutgers University, Piscataway, NJ

P-Sat-246 Microfluidic Chromatin Immunoprecipitation in Nanoliter-scale Droplets A. Oreskovic1, R. Graybill1, M. Modak1, Y. Xu1, S. Doonan1, J. Tice1, T. Ordog2, and R. Bailey1 1

University of Illinois at Urbana-Champaign, Urbana, IL, 2Mayo Clinic, Rochester, MN

P-Sat-247 A Chemical Patterned Paper-Based Microfluidic Device For Biochemical Detections R. Howse1, M. Musallam1, B. DeMessie2 and J. Kim1 1

Texas Tech University, Lubbock, TX, 2William Mason High School, Mason, OH

P-Sat-248 The Development of an Epidermal Electronic Heating Device for Perioperative Warming A. Stier1, K. Diller1, and N. Lu1 1

The University of Texas at Austin, Austin, TX

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

204

BMES 2014

1

University of Houston, Houston, TX

Binghamton University, Binghamton, NY

P-Sat-253 Extending the Spectral Range of Inkjet-Fabricated Paper-Based Plasmonic Enhancing Sensors with Silver Staining C. Lane1 and I. White1 1

University of Maryland, College Park, MD

P-Sat-254 Development of a Salivary Cortisol Sensor Using Surface Plasmon Resonance H. Schmidt1, T. Long1, S. Pautler1, A. Wood1, S. Grant1, and S. Gangopadhyay1 1

University of Missouri, Columbia, MO

P-Sat-255 On-chip Oxygen Gradient Stimulation of Pancreatic Beta Cells F. Choughari1 and M. Mahmoud1 1

University of Michigan-Dearborn, Dearborn, MI

P-Sat-256 Detecting Pesticides with Antibody Conjugated CPMV Nanoparticles J. Kim1, J. Whitney1, and N. Steinmetz2 Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, Cleveland, OH, 2Department of Biomedical Engineering | Radiology | Materials Science and Engineering | Macromolecular Science and Engineering, Case Western Reserve University, Cleveland, OH, Cleveland, OH

1

P-Sat-257 Complement-mediated Cell Death of Leukemia and E. coli Cells with Fc Functionalized Beads M. Devlin1, B. Gizaw1, A. Khaja1, A. Mylarapu1, C. Patonja1, P. Pacheco1, and T. Sulchek1 1

Georgia Institute of Technology, Atlanta, GA

P-Sat-258 Reference Sensors using Poly-acrylonitrile (PAN) Nanobeads for Improved Accuracy in Implantable Optical Sensing Devices M. Schechinger1, R. Unruh1, A. Nagaraja1, J. Weaver1, and M. McShane1 1

Texas A&M, College Station, TX

P-Sat-259 In Vitro Turnover of Endothelial Cells A. Wnorowski1, J. DeStefano1, A. Wong1, and P. Searson1 1

Johns Hopkins University, Baltimore, MD

P-Sat-260 Preasure Measurement In PDMS Microchannels Using The Ideal Gas Law D. Renner1 and X. Luo1 1

The Catholic University of America, Washington, DC

9:30AM – 1:00pm Poster Session Sat

2014 | october 25 | Saturday

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am P-Sat-272 Dexamethasone Attenuates Immediate Microglial Responses to Brain Microdialysis In Vivo as Revealed by Two-Photon Microscopy

Neural Engineering

J. DeVince1 and A. Ritter1 1

Stevens Institute of Technology, Hoboken, NJ

P-Sat-262 The Role of Blood-Derived Macrophages and Resident Microglia in the Neuroinflammatory Response to Implanted Intracortical Microelectrodes S. Sunil1,2, M. Ravikumar1,2, J. Black1, D. Barkauskas1, A. Haung1, R. Miller1, S. Selkirk1,2, and J. Capadona1,2 Case Western Reserve University, Cleveland, OH, 2Louis Stokes Cleveland Veterans Affairs Medical Centre, Cleveland, OH

1

P-Sat-263 Volumetric Differences of the Amygdala, Hippocampus and Caudate Nucleus in Autism Spectrum Disorder M. Weitekamp , V. DelBene , S. Molholm , L. Ross , and J. Foxe 1

1

1

1

1

1

Albert Einstein College of Medicine, Bronx, NY

P-Sat-265 Transient Spectral Dynamics Correlates with Blood Pressure Excursions During MoyaMoya Neurosurgery N. Seo1, S. Ryu2, R. Murphy3, J. Leonard4, and S. Ching2,3 University of Rochester, Rochester, NY, 2Washington University in St. Louis, St. Louis, MO, 3Washington University School of Medicine in St. Louis, St. Louis, MO, 4Nationwide Children's Hospital, Columbus, OH

1

G. Brunette1, T. Kozai1, A. Jaquins-Gerstl1, A. Vazquez1, A. Michael1, and X. Cui1 1

University of Pittsburgh, Pittsburgh, PA

P-Sat-273 Development of Superoxide Dismutase Mimetic Surfaces to Reduce Accumulation of Reactive Oxygen Species for Neural Interfacing Applications M. Gitomer1, K. Potter-Baker1, J. Nguyen1, K. Kovach1, T. Srail1, W. Stewart1, J. Skousen1, and J. Capadona1 1

Case Western Reserve University, Cleveland, OH

P-Sat-274 A Wireless, Real-Time Embedded Hand Gesture Recognition System For Myoelectric Control J. Sacks1, X. Liu2, M. Zhang2, and J. Van der Spiegel2 1

The University of Texas at Austin, Austin, TX, 2University of Pennsylvania, Philadelphia, PA

P-Sat-275 Inhibition Of Cluster Of Differentiation 14 (CD14) Attenuates Neuroinflammation Around Intracortical Microelectrode Interface W. Tomaszewski1, M. Ravikumar1, S. Sunil1, A. Burke1, D. Hageman1, and J. Capadona1 1

Case Western Reserve University, Cleveland, OH

P-Sat-276 Diffusion Tractography as a Tool for Subject-Specific Computational Models of DBS in the MLR

P-Sat-266 The Ladder Rung Walking Task as a Technique to Quantify Traumatic Cerebellar Injury in Rats

K. Brintz1, L. Zitella1, J. Xiao1, Y. Duchin1, G. Adriany1, E. Yacoub1, N. Harel1, and M. Johnson1

J. Binion1,2, S. Keller1,3, G. Ordek1, and M. Sahin1

P-Sat-278 Novel Fractal Electrode Geometries for Efficient Deep Brain Stimulation of Neural Tissue

1 3

New Jersey Institute of Technology, Newark, NJ, 2Grove City College, Grove City, PA, Vanderbilt University, Nashville, TN

P-Sat-267 Model of Blast Traumatic Brain Injury with In Vitro Dorsal Root Ganglia in Shock Tube T. Louk1,2, M. Sisk1,3, M. Skotak1, M. Kuriakose1, A. Adams1, N. Chandra1, and B. Pfister1 1 New Jersey Institute of Technology, Newark, NJ, 2Wartburg College, Waverly, IA, 3George Mason University, Fairfax, VA

P-Sat-268 Determining the Role of IGF-I in Post-Traumatic Epileptogenesis L. Boller1, K. Walters1, C. Pimentel1, Y. Song1, and Y. Berdichevsky1 1

Lehigh University, Bethlehem, PA

1

University of Minnesota, Minneapolis, MN

N. Iyengar1, A. DeMaria1, and X. Wei1 1

The College of New Jersey, Ewing, NJ

P-Sat-279 In Vitro Model For Mimicking Concussion Impacts on Sterile Cell Culture N. Nibras1 and S. Madihally1 1

Oklahoma State University, Stillwater, OK

P-Sat-280 Histological and Biodistribution Assessment of Daily Administration of Resveratrol: Application for Intracortical Microelectrodes W. Stewart1, K. Potter-Baker1,2, W. Meador1, W. Tomaszewski1, M. Gitomer 1, N. Ziats1, and J. Capadona1,2

P-Sat-269 The Effects of Binaural Stimulation on Brainwave Entrainment

1

J. Parks1, M. Harring1, C. Beauchene1, and A. Leonessa1

P-Sat-281 Mechanically-compliant Intracortical Implants Reduce the Neuroinflammatory Response

1

Virginia Polytechnic Institute and State University, Blacksburg, VA

P-Sat-270 Local Field Potentials Indicate Object Presence During Human Neuroprosthetic Control

Case Western Reserve University, Cleveland, OH, 2L. Stokes Cleveland VA Medical Center, Cleveland, OH

Poster Session

J. Nguyen1,2, D. Park1, J. Skousen2, A. Hess-Dunning2, D. Tyler1,2, S. Rowan1,3, C. Weder3,4, and J. Capadona1,2

1

The University of Akron, Akron, OH, 2University of Pittsburgh, Pittsburgh, PA, 3Human Engineering Research Laboratories, Pittsburgh, PA, 4Center for the Neural Basis of Cognition, Pittsburgh, PA, 5Center for Neural Basis of Cognition, Pittsburgh, PA

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 2 Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, 3Department of Macromolecular Science and Engineering, Case Western Reserve University, Cleveland, OH, 4Adolphe Merkle Institute, University of Fribourg, Marly, Switzerland

P-Sat-271 Diffusion Tensor Imaging Segmentation and Tractography of Infantile Nystagmus Syndrome

P-Sat-282 Complexing Blood Proteins and Resveratrol to Increase Reactive Oxygen Species Scavenging for Intracortical Electrode Use

A. Zampini1 and N. Kashou1

T. Srail1, E. Ereifej1, and K. Potter-Baker1

D. Crowder1,2,3, J. Downey2,4, S. Foldes2,4, M. Boninger2,3, and J. Collinger2,3,5

Wright State University, Dayton, OH

1

Undergraduate Research

P-Sat-261 Two-Dimensional Movement Control using a Non-Invasive, Low-Cost, Brain-Computer Interface

1

1

Case Western Reserve University, Cleveland, OH

See page 194 for Poster floor plan

BMES 2014

205

Sat

Poster Session Sat 9:30AM – 1:00pm

saturday | october 25 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM

New Frontiers and Special Topics P-Sat-294 Synthesis and Characterization of a Citrate-based Hydrogel for Injection Assisted Endoscopic Mucosal Resection S. Vilchez Mercedes1, C. Chu1, R. Tran1, and J. Yang1 1

The Pennsylvania State University, State College, PA

P-Sat-295 The Interaction Between Cytochrome B5 and Cytochrome B5 Reductase-1 in Electron Transport E. Kwan1,2, W. Bauer2, and M. Malkowski2 University of Rochester, Rochester, NY, 2Hauptman Woodward Medical Research Institute, Buffalo, NY

1

P-Sat-296 Detecting Electrophysiologic Abnormalities In Chronic Insomnia Using Detrended Fluctuation Analysis A. Cugini1, D. Buysse2, M. Hall2, D. Cashmere2, and F. He2 University of Pittsburgh, Pittsburgh, PA, 2Clinical and Translational Science Institute, Pittsburgh, PA

1

P-Sat-297 Development Of X-ray Irradiation Port For Biological Material At CUEBIT W. Heffron , R. Wilson , D. Medlin , A. Gall , M. Rusin , D. Dean , and E. Takacs2 1

1

2

2

2

2

2

Wofford College, Spartanbug, SC, 2Clemson University, Clemson, SC

P-Sat-298 Bioproduction Of Ethanol Via Co-culture of Ralstonia eutropha and Saccharomyces cerevisiae S. Kakarla1, A. Kehail1, M. Silby1, V. Bucci1, and C. Brigham1 1

University of Massachusetts Dartmouth, North Dartmouth, MA

P-Sat-299 Reagent Stability for Ultra-low-cost Sickle Cell Disease Assay D. Lezzar , N. Piety , and S. Shevkoplyas 1

1

1

1

University of Houston, Houston, TX

P-Sat-300 Design of an Inexpensive Recording Device To Overcome Obstacles Resulting From Low Literacy Rates In Developing Countries C. Fayal1 and S. Graf2 1

University of Connecticut, Stonington, CT, University of Connecticut, Storrs, CT 2

Orthopaedic and Rehabilitation Engineering

Poster Session

Sat

P-Sat-301 Interaction Between Mirror Visual Feedback and Goal-Directed Task Shows Increased Cortical Excitability in Untrained Hemisphere; Possible Stroke Rehabilitation Applications N. Mubin1,2, A. Albanese1,3, M. Yarossi1,4, E. Tunik4, and S. Adamovich1 New Jersey Institute of Technology, Newark, NJ, 2The College of New Jersey, Ewing Township, NJ, 3University of Nevada, Reno, NV, 4Rutgers Biomedical and Health Sciences, Newark, NJ 1

P-Sat-302 The Role Of Scleraxis In Bone Remodeling and Callus Formation During Fracture Healing B. Havelka1, J. McKenzie2, E. Buettmann2, A. Abraham2, M. Silva2, M. Gardner2, and M. Killian2 Saint Louis University, St. Louis, MO, 2Washington University School of Medicine, St. Louis, MO

1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

206

BMES 2014

P-Sat-303 Biomechanical Analysis of Internal Fixation Methods for Distal Interphalangeal Joint Arthrodesis S. Rigot1,2, R. Diaz-Garcia2, R. Debski2, and J. Fowler2 1

University of Rochester, Rochester, NY, 2University of Pittsburgh, Pittsburgh, PA

P-Sat-304 Modeling Finger Pose and Position in a Cable-Actuated Soft Exomusculate Robotic Glove For Stroke Rehabilitation M. Huszagh1, C. Nycz2, and G. Fischer2 1

Vanderbilt University, Nashville, TN, 2Worcester Polytechnic Institute, Worcester, MA

P-Sat-305 Effects of Exercise and Reduced Collagen Crosslinking on Bone Geometry and Microarchitecture in Mice T. Laine1, M. Hammond2, and J. Wallace1,2 Indiana University Purdue University Indianapolis, Indianapolis, IN, 2Purdue University, Indianapolis, IN

1

P-Sat-306 Sleeve Gastrectomy on Obese Rats Impairs Trabecular Bone in Quantity and Quality J. Tan1, J. Abraham1, G. Pagnotti1, V. Patel 1, A. Yang1, M. Altieri1, A. Pryor1, D. Telem1, C. Rubin1, and M. Chan1 1

Stony Brook University, Stony Brook, NY

P-Sat-307 Utilization Of Peak Extraction Force Of Kirschner (K-) Wire And Reference Probe Indentation Parameters As Predictors Of Bone Mineral Density (BMD) S. Denning1, A. Dincer1, R. Pisano1, T. Bowen2, D. Ebenstein1, and E. Kennedy1 1

Bucknell University, Lewisburg, PA, 2Geisinger Health System, Danville, PA

P-Sat-308 A Mechanically Induced Model of Pain and Structural Changes in the Temporomandiular Joint in the Rat T. Zhou1, S. Kartha1, E. Granquist1, and B. Winkelstein1 1

University of Pennsylvania, Philadelphia, PA

P-Sat-309 Development of a Device To Non-Invasively Induce Osteoarthritis Of The Elbow In An Animal Model L. Kahan1 and S. Lake1 1

Washington University in St. Louis, St. Louis, MO

P-Sat-310 First Steps Towards the Development Of An Artificial Vocal Fold Prosthesis M. Sandoe1, G. Burks1, and A. Leonessa1 1

Virginia Tech, Blacksburg, VA

P-Sat-311 Comparing Cyclic Tensile Properties of Porcine Meniscus when Hydrated in PBS versus Synovial Fluid C. Kline1, E. Lakes1, P. McFetridge1, and K. Allen1 1

University of Florida, Gainesville, FL

P-Sat-312 Sleeve Gastrectomy on Obese Rats Reduces the Quantity of Cortical Bone at the Mid Diaphysis J. Abraham1, J. Tang1, G. Pagnotti1, V. Patel1, A. Yang1, M. Altieri1, A. Pryor1, D. Telem1, C. Rubin1, and E. Chan1 1

Stony Brook University, Stony Brook, NY

P-Sat-313 Quantitative Assessment of Gait and Balance for Determining Alignment Parameters for Prosthetic Fitting J. Loayza1, A. Arrinda1, A. Konjengbam2, A. Alfred1, A. Thota1, and R. Jung1 Florida International University, Miami, FL, 2Wakefield Girls High School, Wakefield, United Kingdom

1

9:30AM – 1:00pm Poster Session Sat

2014 | october 25 | Saturday

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am P-Sat-314 Older Adults Learn Equally From Large And Small Errors During Split-Belt Locomotor Adaptation

P-Sat-327 Mechanical Stretch and Aging of Alveolar Epithelial Cells induces Endoplasmic Reticulum Stress and Pro-inflammatory Gene Expression

H. Harker1, C. Sombric1, P. Sparto1, and G. Torres-Oviedo1

J. Nkwocha1, J. Herbert1, A. Reynolds1, and R. Heise1

1

1

P-Sat-315 Alignment of Hinged Dynamic External Fixators Using the Elbow's FlexionExtension Axis of Rotation F. Unukpo1, R. Baker1, C. Kopfler1, C. Lobrano2, D. O'Neil1, and A. Hollister2 Louisiana Tech University, Ruston, LA, 2Louisiana State University Health Sciences Center, Shreveport, LA

1

P-Sat-316 Effect of Ankle Immobilization on Able-Bodied Gait to Model Bilateral Transtibial Amputee Gait A. Nepomuceno1, M. Major1,2, R. Stine2, and S. Gard1,2 Northwestern University Prosthetics-Orthotics Center, Chicago, IL, 2Jesse Brown VA Medical Center, Chicago, IL

1

P-Sat-317 Altered Trabecular Bone In An Animal Model Of Post-Traumatic Elbow Stiffness M. Liu1, R. Castile1, L. Galatz1, and S. Lake1 1

Washington University in St. Louis, St. Louis, MO

P-Sat-318 Use of Natural Crosslinkers to Stabilize Decellularized Cartilage A. Pinheiro1,2, A. Gottipati2, and S. Elder2 1

P-Sat-328 Assessment of Ventilatory Function and Respiratory Muscle Electromyograms in Rodents for Design of an Adaptive Ventilatory Neuromuscular Pacing Device B. Davis1, R. Siu1, B. Hillen1, C. Vale1, and R. Jung1 1

P-Sat-319 Development of Silver Doped Tricalcium Phosphate Thin Films for the Coating of Magnesium Implants T. Moses1, G. Harris2, E. Craven2, N. Yamoah2, R. Kotoka2, S. Ibrahim2, S. Ajinola2, and D. Kumar2 Clemson University, Clemson, SC, 2North Carolina Agricultural and Technical State University, Greensboro, NC

1

Florida International University, Miami, FL

Track: Undergraduate Research

Stem Cell Engineering P-Sat-337 Redirecting Intestinal Stem Cell Fate Using Small Molecules K. Benjamin1, S. Mohammadi1, and E. Wiellette1 1

Novartis Institutes for Biomedical Research, Cambridge, MA

P-Sat-338 Combined Role of Basic Fibroblast Growth Factor and pH on Glioblastoma Stem Cell Expansion E. Haley1, S. Tilson1, D. Dozier1, and Y. Kim1 1

The University of Akron, Akron, OH, 2Mississippi State University, Mississippi State, MS

Virginia Commonwealth University, Richmond, VA

Undergraduate Research

University of Pittsburgh, Pittsburgh, PA

The University of Alabama, Tuscaloosa, AL

P-Sat-339 The Effect of Y-27632 on the Propagation of Glioblastoma Stem Cells S. Tilson1, E. Haley1, D. Dozier1, G. Yancey Gillespie2, and Y. Kim1 University of Alabama, Tuscaloosa, AL, 2University of Alabama at Birmingham, Birmingham, AL

1

P-Sat-340 Improving Transfection Efficiency of Nucleofection Technique by Manipulating Cell Concentration M. Bloom1, A. Mellott1, M. Detamore1, and H. Shinogle1 1

Respiratory Bioengineering P-Sat-322 Darcy Permeability Characterization of PMP Hollow Fiber Membrane Bundles B. D'Aloiso1, S. Madhani1, B. Frankowski1, and W. Federspiel1,2 Medical Devices Lab, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA

1

P-Sat-323 Design of Collapsible Tubing System for Simulated Airway Reopening C. Faulman1, E. Yamaguchi1, and D. Gaver1 1

Tulane University, New Orleans, LA

P-Sat-324 Computational and Experimental Analysis of Mucus Adhesive Properties during Otitis Media J. McGuire1, J. Malik2, N. Higuita-Castro2, and S. Ghadiali2 1

University of Kansas, Lawrence, KS

P-Sat-341 The Role of Hydrocortisone in the Maturation of Pancreatic Endocrine Beta-like Cells Derived from Murine Embryonic Stem Cells In Vitro J. Choe1 and H. Ku2 1

University of California, Berkeley, Berkeley, CA, 2City of Hope, Duarte, CA

P-Sat-342 Adipose-Derived Stem Cells From Diabetic Patients Display A ProThrombogenic Phenotype D. Pezzone1,2, J. Krawiec1,2, J. Weinbaum1,2, J. Rubin1,2, and D. Vorp1,2 University of Pittsburgh, Pittsburgh, PA, 2McGowan Institute for Regenerative Medicine, Pittsburgh, PA

1

P-Sat-343 Investigating the Effects of Stromal Cell - Neuronal Cell Co-culture on Neuronal Maturity and Neuronal Viability Under Oxidative Stress

Poster Session

Sat

K. Smith1, P. Moghe2, N. Bennett2, and N. Francis2 University of Connecticut, Storrs, CT, 2Rutgers, The State University of New Jersey, Piscataway, NJ

1

Virginia Tech, Blacksburg, VA, The Ohio State University, Columbus, OH 2

P-Sat-325 The Use Of Exhaled Breath Condensate To Assess Surfactant Dysfunction From Chlorine Exposure

P-Sat-344 Optimization Of Polyethyleneimine Coated Gold Nanorods For Use In Caspase-3-siRNA Knockdown Of Adipose-Derived Stem Cells

C. Edwards1, E. Svendsen1, and D. Gaver1

B. Henson1, D. Santiesteban1, L. Suggs1, and S. Emelianov1

1

1

Tulane University, New Orleans, LA

The University of Texas at Austin, Austin, TX

P-Sat-326 A Microfluidic Model of Pulmonary Airway Reopening in Asymmetric Bifurcating Networks

P-Sat-345 Cytoskeletal Remodeling due to Applied Shear Stress in Differentiating Pluripotent Stem Cells

L. Nolan1, E. Yamaguchi1, and D. Gaver1

J. Guidry1, R. Wolfe1, and T. Ahsan1

1

Tulane University, New Orleans, LA

1

Tulane University, New Orleans, LA

See page 194 for Poster floor plan

BMES 2014

207

saturday | october 25 | 2014

Poster Session Sat 9:30AM – 1:00pm   Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM

P-Sat-346 Human Mesenchymal Stem Cell Response to a Patterned and Electrostimulated Monolayer of Graphene

P-Sat-358 Quantifying Cell Aggregation in 3D Smooth Muscle Cell Tissue Rings

B. Fang1

1

1

Vanderbilt University, Nashville, TN

P-Sat-359 Development of a Tendon Graft for Rotator Cuff Repair Using the Human Amniotic Membrane

N. White1, J. Zamora1, R. Burtzlaff1, D. Glaser1, and K. McCloskey1

J. Liu1, M. Mouchiroud1, J. Arrizabalaga1, and M. Nollert1 University of Oklahoma, Norman, OK

1

1

Tissue Engineering

P-Sat-360 Cell Surface Engineering of Embryonic Stem Cells with Modular Biomaterial Chemistries

P-Sat-349 Sustained Protein Release from Tissue Engineering Scaffolds for Bone Regeneration Using Layer-by-Layer Coating M. Lee1, M. Keeney1, X. Jiang1, and F. Yang1 Stanford University, Stanford, CA

1

R. Yada1, N. Bansal1, and G. Underhill1 University of Illinois at Urbana-Champaign, Champaign, IL

1

P-Sat-361 Development of Nerve Guidance Conduit for Peripheral Nerve Regeneration from Urinary Bladder Matrix C. Loveland1,2, B. Young1, C. Valmikinathan1, and T. Gilbert1

P-Sat-350 Enhanced Human Bone Marrow Mesenchymal Stem Cell Behavior on Novel 3D Printed Osteochondral Nanocomposite Scaffolds R. Patel1, N. Castro1, and L. Zhang1

1

ACell, Inc., Columbia, MD, 2Johns Hopkins University, Baltimore, MD

P-Sat-362 Oxygen Sensing Microparticles For Use In Tissue Engineering Scaffolds N. Vera-Gonzalez1, N. Virdone1, B. Nsiah1, and J. West1

The George Washington University, Washington, DC

1

1

P-Sat-351 Enhancing Bone Regeneration by using Osteoinductive Microspheres

P-Sat-363 Influence of the Elastic Modulus of Aligned Electrospun Fibers on Mesenchymal Stem Cell Behavior in Collagen Gels

C. Dodson1, C. Haase1, R. Kaunas1, and C. Gregory2 1

Texas A&M University, College Station, TX, 2Texas A&M Health Science Center, Temple, TX

P-Sat-352 β-Catenin Signaling Leading to Cell Maintenance or Differentiation in Response to Electrospun Fibers R. Nagurney1 and J. Brown1 1

The Pennsylvania State University, State College, PA

P-Sat-353 Mechanical Characterization Of Extracellular Matrix Hydrogels For Peripheral Nerve Reconstruction D. Srinivasachar1, T. Prest1, and B. Brown1 1

University of Pittsburgh, Pittsburgh, PA

P-Sat-354 Adipose Stem Cell Suspension in Keratin Hydrogel for Nervous Tissue Regeneration L. Marra1, D. Minteer1, and K. Marra1,2 University of Pittsburgh, Pittsburgh, PA, 2McGowan Institute for Regenerative Medicine, Pittsburgh, PA

1

P-Sat-355 Single Walled Carbon Nanohorns Modulate Extracellular Matrix Response in Tendons and Ligaments

Sat

University of Rhode Island, Kingston, RI, 2Worcester Polytechnic Institute, Worcester, MA

P-Sat-347 Site Directed Differentiation of Using a Fibronectin-VEGF Matrix Blend University of California, Merced, Merced, CA

Poster Session

C. Nunez1, K. Levi2, and M. Rolle2

J. Jackson1, E. Ekwueme2, A. Pekkanen3, P. Brolinson4, M. Rylander3, and J. Freeman2 Rensselaer Polytechnic Institute, Troy, NY, 2Rutgers Univeristy, Piscataway, NJ, 3Virginia Tech, Blacksburg, VA, 4Edward Via Virginia College of Osteopathic Medicine, Blacksburg, VA 1

P-Sat-356 Design of a Mold System for 3D Self-Assembly of Skeletal Muscle In Vitro M. Mancuso , J. Forte , and R. Page 1

1

2

2

Union College, Schenectady, NY, 2Worcester Polytechnic Institute, Worcester, MA

P-Sat-357 Development of Carbon Nanotube Hydrogel Composites D. Vasileva , K. Shah , and S. Zustiak 1

1

1

Saint Louis University, St Louis, MO

1

N. Butler-Abisrror1, P. Thayer2, and A. Goldstein2 Virginia Polytechnic Institute and State University, Richmond, VA, 2Virginia Polytechnic Institute and State University, Blacksburg, VA

1

P-Sat-364 Creation of a Functional Mitral Regurgitation Reversal Model in a Physiological Flow Loop Bioreactor S. Kim1, P. Connell1, M. Jackson2, S. Little 2, and J. Grande-Allen1 1

)

208

BMES 2014

Rice University, Houston, TX, 2The Methodist Hospital, Houston, TX

P-Sat-365 Transcriptional Activator TAZ Increases Fibroblast ECM Deposition in the Context of Pulmonary Fibrosis L. Stopfer1,2, A. Jorgenson1, D. Sicard1, and D. Tschumperlin1 1

Mayo Graduate School, Rochester, MN, 2University of Wisconsin Madison, Madison, WI

P-Sat-366 Precise Triaxial Deposition of Near Field Electrospun Nanofibers for the Fabrication of Tissue Scaffolds J. Dover1 and J. Brown1 1

The Pennsylvania State University, University Park, PA

P-Sat-367 Characterization Of Highly Aligned Collagen Sponge-Like Scaffolds For Nerve Tissue Engineering M. Grota1, C. Lowe2, and D. Shreiber2 University of Massachusetts Dartmouth, New Bedford, MA, 2Rutgers The State University of New Jersey, New Brunswick, NJ

1

P-Sat-368 Prevascularization of Natural Extracellular Matrix Scaffold M. Tahtinen1, L. Zhang1, and F. Zhao1 1

Michigan Technological University, Houghton, MI

P-Sat-369 Bell-shaped Dose Response Of Sodium Pyruvate On Properties Of Tissue Engineered Cartilage S. Bansal1, E. Estell1, G. Ateshian1, and C. Hung1 1

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

Duke University, Durham, NC

Columbia University, New York, NY

9:30AM – 1:00pm Poster Session Sat

2014 | october 25 | Saturday

  Poster Viewing with Authors & Refreshment Break  | 9:30am - 10:30am P-Sat-370 The Effect Of Interleukin β On VLDL Secretion In Steatotic Hepatocytes During Defatting

P-Sat-382 Increasing Engineered Cardiac Muscle Tissue Alignment in 2D

A. Chen-Liaw1, G. Yarmush2, and F. Berthiaume2

1

P-Sat-371 Extraction of Platelet-Rich Plasma Derived Lipids from Electrospun Structures for Wound Healing K. Polito and S. Sell 1

1

1

Saint Louis University, St. Louis, MO

P-Sat-372 Investigating the Response of Fibroblasts to Microgravity: an In Vitro Platform to Study Wound Healing S. Brady1, L. Stapleton2, E. Evans1, and D. Hoffman-Kim1 1

Brown University, Providence, RI, University of New Mexico, Albuquerque, NM 2

P-Sat-373 Preventing Articular Cartilage Calcification by the Controlled Release of Dorsomorphin P. Bianconi1,2, R. Gottardi1,3,4,5,6, V. Ulici1,4, S. Little1,2,7, and R. Tuan1,3,4 University of Pittsburgh, Pittsburgh, PA, 2Department of Bioengineering, Pittsburgh, PA, 3 McGowan Institute for Regenerative Medicine, Pittsburgh, PA, 4Orthopedic Surgery, Pittsburgh, PA, 5Ri.Med Foundation, Palermo, Italy, 6Department of Mechanical Engineering, Pittsburgh, PA, 7Department of Chemical Engineering, Pittsburgh, PA 1

P-Sat-374 Peptide linkage of Poly(caprolactone)-Chitosan Blend Scaffolds M. Sanchez , D. Ramos , , C. Laurencin , , , and S. Kumbar , , 1

1 2

1 2 3

1 2 3

University of Connecticut, Storrs, CT, 2Institute For Regenerative Engineering, Farmington, CT, 3University of Connecticut Health Center, Farmington, CT

1

P-Sat-375 Extended Bioreactor Conditioning of MNC Seeded Heart Valves C. Uryasz1, M. VeDepo1, C. McFall1, K. Neill1, R. Hopkins1, and G. Converse1 1

Children's Mercy Hospital, Kansas City, MO

P-Sat-376 UCP-1 Expression in White Adipose Depots in Laminin α4 Knockout Mice A. Wanagas , M. Vaicik , M. Morse , R. Cohen , and E. Brey 1

1

1

2

2

1

Illinois Institute of Technology, Chicago, IL, 2University of Chicago, Chicago, IL

V. Niba , L. Bracaglia , and J. Fisher 1

Harvey Mudd College, Claremont, CA

1

P-Sat-384 Biodegradable Polyurethane and Its Application in Tissue Engineering R. Aekins1, D. Dorcemus1, R. Bezwada2, and S. Nukavrapu3 University of Connecticut, Storrs, CT, 2Bezwada Biomedical LLC, Hillsborough, NJ, University of Connecticut, Farmington, CT

1 3

P-Sat-385 Glioma Stem Cells Respond Differentially to Treatment in Tissue Engineered Brain Tumor Microenvironments A. Berr1, O. Cossio1, and J. Munson1 University of Virginia, Charlottesville, VA

1

P-Sat-386 Spatiotemporal Oxygen Monitoring for Three-Dimensional Engineered Tissues S. Knowlton1, A. Acun2, and P. Zorlutuna2 University of Connecticut, Storrs Mansfield, CT, 2University of Notre Dame, Notre Dame, IN

1

P-Sat-387 Three Dimensional Cell Culture Effects on Chondrogenesis of Kartogenintreated hMSCs M. Patil1, R. Gottardi1,2,3, V. Ulici3, S. Little1, and R. Tuan3 Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, 2Ri.MED Foundation, Palermo, Italy, 3McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA

1

P-Sat-388 A Long Term Imaging Platform for Patterned Substrates E. Tague1 The University of Illiniois Urbana-Champaign, Batavia, IL

1

P-Sat-389 Alignment-Induced RNA Expression of Endothelial Cells University of California, Merced, Merced, CA

1

University of Maryland, College Park, MD

P-Sat-378 Three-Dimensional Microfluidic Computational Study in Tissue Engineering J. Stewart1 Tarleton State University, Stephenville, TX

1

P-Sat-379 Cell Culture on Photovoltaic Surfaces: An Alternative to Trypsinization C. Arthur1, A. Stastny1, C. Jones1, A. Desai1, D. Dean1, and J. Rodriguez-Devora1 1 Clemson University, Clemson, SC

P-Sat-380 Developing an In Vitro Cardiac Infarct Model With Silk and Cardiac Progenitor Cells 1

Tufts University, Medford, MA

1

Track: Undergraduate, Translational Biomedical Engineering

Translational Biomedical Engineering Undergraduate Research P-Sat-396 Synth-AID: A Synthetic Skin Delivery System K. Cyr and C. Marasco 1

Poster Session

Sat

1

Vanderbilt University, Nashville, TN

1

P-Sat-397 Optimizing Antibiotic Treatment Strategies Using Small Molecule Inhibitors of DNA Damage Repair H. Thorp1,2, J. Yang1,2, and J. Collins1,2

P-Sat-381 Mechanical Properties & Degradation of Hydroxyapatite & Tri-Calcium Phosphate Incorporated Hydrogels D. Kamireddi1, B. Akar2, and E. Brey2 1

K. Curlin1 and E. Orwin1

1

1

A. Greaney

P-Sat-383 Rabbit Corneal Fibroblast Response to Substrate Stiffness

I. Buczko1 and K. McCloskey 1

P-Sat-377 Cellular Response To PPF Reinforced Pericardium Scaffold 1

Carnegie Mellon University, Pittsburgh, PA

Undergraduate Research

University of Scranton, Scranton, PA, 2Rutgers, The State University of New Jersey, Piscataway, NJ

1

S. Kim1, I. Batalov1, and A. Feinberg1

University of Connecticut, Storrs, CT, 2Illinois Institute of Technology, Chicago, IL

Boston University, Boston, MA, 2Howard Hughes Medical Institute, Boston, MA

1

P-Sat-398 Synthesizing PLA-PEG Nanoparticles With A Fluidic Nanoprecipitation System For Industrial Scale Up N. Schindler1, M. Lashof-Sullivan1, R. Groynom1, and E. Lavik1 Case Western Reserve University, Cleveland, OH

1

See page 194 for Poster floor plan

BMES 2014

209

Poster Session Sat 9:30AM – 1:00pm

saturday | october 25 | 2014

  Poster Viewing with Authors & Refreshment Break  | 9:30AM - 10:30AM P-Sat-399 Efficient Expression and Purification of Beta Amyloid 42 T. Armand1, S. Sharma1, and T. Head-Gordon1 1University of California, Berkeley, Berkeley, CA P-Sat-400 Computational Modeling of Pancreatic Duct Strictures as a Predictor for Stent Therapy C. Moreau1 and C. Lee2 University of Texas Health Science Center at San Antonio, San Antonio, TX, 2University of Texas at San Antonio, San Antonio, TX

1

P-Sat-401 The Impact of Mild Cognitive Impairment on Balance and Gait: a Systematic Review L. Bahureksa1, M. Schwenk1, A. Saleh1, M. Sabbagh2, D. Coon3, J. Mohler1, and B. Najafi1 1 3

University of Arizona, Tucson, AZ, 2Banner Sun Health Research Institute, Sun City, AZ, Arizona State University, Phoenix, AZ

P-Sat-402 Structural and Functional Analysis of Neonatal Fibrin Clots R. Hannan1, A. Brown1, J. Fernandez2, N. Guzzetta2,3, and T. Barker1 1 3

Georgia Institute of Technology, Atlanta, GA, 2Children's Healthcare of Atlanta, Atlanta, GA, Emory University, Atlanta, GA

P-Sat-403 Patient-Derived Biomaterials for Bone Regeneration C. Stephens1, P. Mikael2, and S. Nukavrapu2 1

Syracuse University, Syracuse, NY, 2University of Connecticut, Farmington, CT

Poster Session

Sat

P = Poster Session OP = Oral Presentation = Reviewer Choice Award

)

210

BMES 2014

henry b. gonzales convention center Henry B. Gonzales Convention Center 200 East Market Street San Antonio, TX 78205 (210) 207-8500

204B

RIVER LEVEL

BALLROOM B BELOW

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BRIDGE HALL BELOW

008B

007C 007B

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BALLROOM A B ELOW

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203B 203A 202B 202A

LOBBY BRIDGE

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A L A M O

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WELCOME RECEPTION

E XHIB IT HALL B B ELOW

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GREEN ROOM

005 REHEARSAL HALL

CONCOURSE L EV EL

ESCALATORS

006A

003B 003A

004 VIP ROOM

002B 002A 001B

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RIVER LEVEL

M A R K E T

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PLENARY SESSIONS

LOB B Y B R I DGE

CAFÉ

I NFOR MATI ON B OOTH

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MAIN ENTRANCE

LUNCHEONS

BMES 2014

211

Thursday | october 23 | 2014

Program at-a-glance

Track

8:00am – 9:30am

2:00pm - 3:30pm

4:30pm - 6:00pm

Bioinformatics, Computational and Systems Biology

Single Cell, Heterogeneity, Noise

Multiscale Modeling

Cell Regulatory Circuits

Room 202A

Room 202A

Room 202A

Biomaterials

Biomaterial Scaffolds I

Engineering Cells and Pathways via Synthetic and Systems Biology

Room 007D Room 006A Bioinspired and Self Assembling Biomaterials I

Room 006B

Therapeutic and Theranostic Biomaterials I

Therapeutic and Theranostic Biomaterials II

Room 006A

Room 006A

Biomaterials for Controlling Cell Environment I

Biomaterials for Controlling Cell Environment II

Room 006B

Room 006B Hepatic, Pancreatic, Digestive & Renal Tissue Engineering

Room 001A

BIOMECHANICS

Cell Biomechanics I

Cell Biomechanics II

Heart Valve Biomechanics

Room 006D

Room 006D

Room 006D

Head Injury

Spine Biomechanics

Room 103B

Room 103B

Methods for Assessing Injury and Injury Risk

Mechanotransduction I

Mechanotransduction II

Room 007D

Room 007D

Skeletal Muscle Mechanics

Room 103B Cardiovascular Flow Modeling in Health and Disease

Room 007B

Room 202B

Structure-Function Relationships in Musculoskeletal Tissues

Room 202B

Biomedical Engineering Education

Innovations in BME Education

Teaching in a Flipped Classroom

Room 203B

Room 203B

Effective Use of Technology in the BME Classroom

Biomedical Imaging & Optics

Applied Biomedical Imaging Techniques

Molecular Probes I

Molecular Probes II

Room 203A

Room 203A

Room 203A

Room 203B

Musculoskeletal Imaging

Room 202B

Cancer Technologies

Cancer Mechanobiology

Tumor Microenvironment I

Tumor Microenvironment II

Room 007A

Room 007A

Room 007A

Cardiovascular Engineering

Hemodynamics and Vascular Mechanics I

Hemodynamics and Vascular Mechanics II

Cardiovascular Flow Modeling in Health and Disease

Room 007B

Room 007B

Room 007B

Blood Vessel Tissue Engineering

Cardiovascular Devices: Intelligent Design Using Computations and Experiments

Heart Valve Biomechanics

Room 001A

Room 006D

Room 201

Cellular & Molecular Bioengineering

Cell Adhesion

Room 007C Mechanotransduction I

Room 007D Cell Biomechanics I

Room 006D Microfluidic Platforms I

Room 008B

Cell Adhesion and the Extracellular Matrix Interaction

Cell Interactions with the Extracellular Matrix

Room 007C

Room 007C

Mechanotransduction II

Engineering Cells and Pathways via Synthetic and Systems Biology

Room 007D Biomaterials for Controlling Cell Environment I

Room 006B Cell Biomechanics II

Room 007D Biomaterials for Controlling Cell Environment II

Room 006B

Room 006D Microfluidic Platforms II

Room 008B

DEVICE TECHNOLOGIES AND BIOMEDICAL ROBOTICS

Implantable Devices and Implantable Electronics

Room 201 Biomedical Products and Devices

Ballroom A

212

BMES 2014

Cardiovascular Devices: Intelligent Design Using Computations and Experiments

Room 201

Medical Device Technologies

Room 201

Program at-a-glance

2014 | october 23 | Thursday

Track

8:00am – 9:30am

2:00pm - 3:30pm

4:30pm - 6:00pm

DRUG DELIVERY

Nano/Micro Drug Delivery

Room 006C

Drug Delivery in Tissue Engineering I

Drug Delivery in Tissue Engineering II

Room 006C

Room 006C

BioMEMS I

BioMEMS II

Paper Fluidics

Room 008A

Room 008A

Room 008A

Microfluidic Platforms I

Microfluidic Platforms II

Microfluidic Platforms III

Room 008B

Room 008B

Room 008B

NANO AND MICRO TECHNOLOGIES

Nano/Micro Drug Delivery

Room 006C

Neural Engineering

Head Injury

New Frontiers & Special Topics

Microfluidic Platforms I

Microfluidic Platforms II

Paper Fluidics

Room 008B

Room 008B

Room 008A

Room 103B

Implantable Devices and Implantable Electronics

Hepatic, Pancreatic, Digestive & Renal Tissue Engineering

Room 201

Room 001A

Microfabrication and 3D Printing for Tissue Engineering

Room 001B Biomedical Products and Devices

Ballroom A

ORTHOPEDIC AND REHABILITATION ENGINEERING

Skeletal Muscle Mechanics

Musculoskeletal Imaging

Room 202B

Room 202B Spine Biomechanics

STEM CELL ENGINEERING

Microfabrication and 3D Printing for Tissue Engineering

Tissue Engineering

Blood Vessel Tissue Engineering

Structure-Function Relationships in Musculoskeletal Tissues

Room 202B

Room 103B

Orthopaedic Biomechanics

Tissue Engineering of Models for Study of Disease and Drug Discovery

Hepatic, Pancreatic, Digestive & Renal Tissue Engineering

Room 204A

Room 001B Room 001A Microfabrication and 3D Printing for Tissue Engineering

Room 001B Biomaterial Scaffolds I

Room 006A

Room 001A Scaffolds and Surfaces for Tissue Engineering I

Room 001B Drug Delivery in Tissue Engineering I

Room 001A Scaffolds and Surfaces forTissue Engineering II

Room 001B Drug Delivery in Tissue Engineering II

Room 006C

Room 006C

TRANSLATIONAL BIOMEDICAL ENGINEERING

Biomedical Products and Devices

Ballroom A Applied Biomedical Imaging Techniques

Room 203A Microfluidic Platforms I

Overcoming Challenges and Obstacles for Clinical Translation: From Bench to Bedside

Paper Fluidics

Room 008A

Room 204A Microfluidic Platforms II

Room 008B

Room 008B Microfabrication and 3D Printing for Tissue Engineering

Room 001B

Other

8:00 – 9:30am Professional Integrity Workshop

Room 102AB

STUDENT AND EARLY CAREER

9:00 – 10:30am What Do Biomedical Engineers Actually Do? What Are the Specialization Areas?

Room 103A

2:00-6:00pm BMES-NSF Special Session on Research & Grant Writing

4:00-7:30pm Korea-US Joint Workshop in Biomedical Engineering

Room 004

Ballroom A

1:30 – 2:45pm How to Get Your First Job

3:15 – 4:30pm Networking for Career Success

Room 103A

Room 103A

2:00-4:00pm Resume Review & Critique

5:00 – 6:15pm Mock Interview

Room 102AB

Room 103A BMES 2014

213

friday | October 24 | 2014

Program at-a-glance

Track

8:00am – 9:30am

1:45pm - 2:45pm

3:00pm – 4:00pm

Bioinformatics, Computational and Systems Biology

Signaling Systems Analysis

System Proteomics: Measurement and Computation

Prokaryotic Systems Biology

Biomaterials

Intelligent/Multifunctional Biomaterials

Room 202A

Room 006A Bone & Cartilage Tissue Engineering I

Room 008B

Room 202A Biomaterial Scaffolds II

Room 202A

Room 006A

Bioinspired & Self Assembling Biomaterials II

Bone & Cartilage Tissue Engineering II

Engineering Stem Cell Environments

Room 008B

Room 006A Room 001A Scaffolds and Surfaces for Tissue Engineering III

Room 008B

BIOMECHANICS

Mechanics of Biomaterials

Impact and Injury Biomechanics

Room 103B

Room 103B

Cell-Cell Interactions and Intercellular Forces

Computational Modeling of the Respiratory System

Room 203B

Room 203B

Biomedical Engineering Education Biomedical Imaging & Optics

Countermeasures for Bone Loss and Injury

Room 103B Translational Research Relevant to Common Orthopaedic Injuries

Room 007D

Design in BME Education

Room 006 Magnetic Resonance Imaging I

Magnetic Resonance Imaging II

Imaging Strategies in Cancer

Room 202B

Room 202B

Room 007A

Diagnostic Devices and Biosensors I

Diagnostic Devices and Biosensors II

Room 203A

Room 203A Cardiovascular Flow Imaging and Modeling in Health and Disease

Room 007B

Cancer Technologies

Engineered Models of Cancer I

Engineered Models of Cancer II

Imaging Strategies in Cancer

Room 007A

Room 007A

Room 007A

Cardiovascular Engineering

Cardiac Electrophysiology and Mechanics

Cardiovascular Flow Imaging and Modeling in Health and Disease

Structure-Function Relationship in the Cardiovascular System

Room 006B Cardiovascular Assist Devices

Room 007B

Room 007B

Room 007B

Cellular & Molecular Bioengineering

Molecular and Cell Engineering I

Molecular and Cell Engineering II

Cell Motility

Room 007C

Room 007C

Room 007C

Cell-Cell Interactions and Intercellular Forces

Engineering Stem Cell Environments

Room 001A

Room 203B

DEVICE TECHNOLOGIES AND BIOMEDICAL ROBOTICS

Wearable Technology

Room 201 Cardiovascular Assist Devices

Room 007B

Verification and Validation of Computational Models of Medical Devices

Biomedical Robotics

Room 201

Room 201 Peripheral Neural Interfaces: Simulation & Recording

Room 001B

DRUG DELIVERY

NANO AND MICRO TECHNOLOGIES

Nucleic Acid Delivery

Room 006C

Novel Materials and Self Assembly

Nanobiointerfaces

Diagnostics

Nanoparticles and Theranostics

Room 008A

Room 008A

Room 008A

Peripheral Neural Interfaces: Simulation & Recording

Neural Control and Modeling

Room 006C

Multifunctional Drug Delivery

Room 006C

Bio-nanomedicine in Healthcare

Room 006D

Neural Engineering

CNS Injury: SCI, TBI and Concussions

Room 001B Neural Tissue Engineering

Room 001A

214

BMES 2014

Room 001B

Room 001B Neural Engineering: Controlling Cell Behavior

Room 006B

Program at-a-glance Track

8:00am – 9:30am

1:45pm - 2:45pm

New Frontiers & Special Topics

Intelligent/Multifunctional Biomaterials

Bioelectronics

ORTHOPEDIC AND REHABILITATION ENGINEERING

Room 006A

FRIDAY | October 24 | 2014

3:00pm – 4:00pm

Room 006D

Diagnostic Devices and Biosensors I

Diagnostic Devices and Biosensors II

Room 203A

Room 203A

Wearable Technology

Diagnostics

Room 201

Room 008A

Pain

Rehabilitation Engineering: Prosthetics and Wearable Devices

Translational Research Relevant to Common Orthopaedic Injuries

Room 007D

Room 007D

Room 007D Bone & Cartilage Tissue Engineering I

Room 008B

Peripheral Neural Interfaces: Simulation & Recording

Room 001B Bone & Cartilage Tissue Engineering II

Room 008B

RESPIRATORY BIOENGINEERING

Computational Modeling of the Respiratory System

Stem Cell Engineering

Epithelial and Adipose Tissue Engineering

Room 203B

Room 001A

Engineering Stem Cell Environments

Room 001A Translational Therapeutics for Regenerative Medicine

Room 006D

Tissue Engineering

Neural Tissue Engineering

Room 001A Bone & Cartilage Tissue Engineering I

Room 008B

Epithelial and Adipose Tissue Engineering

Scaffolds and Surfaces for Tissue Engineering III

Room 001A

Room 008B

Bone & Cartilage Tissue Engineering II

Room 008B Biomaterial Scaffolds II

Room 006A

TRANSLATIONAL BIOMEDICAL ENGINEERING

Bio-nanomedicine in Healthcare

Diagnostics

Room 006D

Room 008A

Other

Whitaker International

Bioelectronics

Translational Therapeutics for Regenerative Medicine

Room 006D

Room 006D Room 204A

2:00-4:00pm Diversity, Health Disparities and Affordable Healthcare

Room 004

STUDENT AND EARLY CAREER

8:30 – 9:30am Student Chapter Outstanding Best Practices

1:30 – 2:30pm Owning Your Career & Using Mentors

Room 103A

Room 103A

9:30 – 10:30am Chapter Outreach & Mentoring Best Practices

2:00-4:00pm Resume Review & Critique

Room 103A

Room 102AB

BMES 2014

215

saturday | october 25 | 2014

Program at-a-glance

Track

8:00am – 9:30am

1:30pm - 3:00pm

3:15pm - 4:45pm

Biomaterials

Micro and Nanostructured Materials

Biomaterial for Immunoengineering I

Biomaterial for Immunoengineering II

Room 001B

Room 001B Biomaterials Design I

Room 006A

BIOMECHANICS

Cardiovascular Biomechanics I

Aortic Biomechanics

Room 006B

Room 006B Ocular Biomechanics

Room 006C

Room 001B Biomaterials Design II

Room 006A Biomechanics in Degeneration and Regeneration

Room 006B Multiscale Biomechanics

Room 006C Mechanobiology in the Respiratory System

Room 008B

Biomedical Engineering Education

Novel Laboratory Modules

Biomedical Imaging & Optics

Ultrasound Imaging

Room 204A

Room 203A Optical Imaging and Microscopy I

Cancer Technologies

Novel Approaches to Biomedical Imaging

Room 203A

Macro/Micro Design for Neurotechnologies: Networked Neural Sensors and Instrumentation

Room 202A

Room 203B

Optical Imaging and Microscopy II

Nanotechnologies for Cancer I

Nanotechnologies for Cancer II

Microtechnologies for Cancer II

Room 103A

Room 103A

Room 006D

Cancer Drug Delivery I

Microtechnologies for Cancer I

Cancer Drug Delivery III

Room 103B

Room 006D

Room 103B

Room 203B

Cancer Drug Delivery II

Room 103B

Cardiovascular Engineering

Cardiac Muscle and Valve Tissue Engineering

Room 001A Microcirculation

Room 006A

Heart Valves & Stents I

Heart Valves & Stents II

Room 007B

Room 007B

Aortic Biomechanics

Room 006B

Cardiovascular Biomechanics I

Room 006B Cardiac Regeneration

Room 006D Angiogenesis

Room 007B

Cellular & Molecular Bioengineering

DEVICE TECHNOLOGIES AND BIOMEDICAL ROBOTICS

Cellular and Molecular Immunoengineering

Biomaterial for Immunoengineering I

Room 006C

Room 001B

Young Innovator Session I

Young Innovator Session II

Room 007C

Room 007C

Biosensors I: Materials and Techniques

Biosensors II: Applications

Room 201 Cells Tissues and Organs on Chip I

Room 008A Global Health I

Room 202B

Biomaterial for Immunoengineering II

Room 001B

Room 201 Cells Tissues and Organs on Chip II

Room 008A Global Health II

Room 202B

Brain Computer Interfaces

Room 202A

DRUG DELIVERY

216

BMES 2014

Cancer Drug Delivery I

Cancer Drug Delivery II

Cancer Drug Delivery III

Room 103B

Room 103B

Room 103B

Targeted Drug Delivery I

Targeted Drug Delivery II

Room 007D

Room 007D

Program at-a-glance

saturday | october 25 | 2014

Track

8:00am – 9:30am

1:30pm - 3:00pm

3:15pm - 4:45pm

NANO AND MICRO TECHNOLOGIES

Cells Tissues and Organs on Chip I

Cells Tissues and Organs on Chip II

Room 008A

Room 008A

Micro and Nanostructured Materials

Microtechnologies for Cancer I

Macro/Micro Design for Neurotechnologies: Networked Neural Sensors and Instrumentation

Room 001B

Room 006D

Nanotechnologies for Cancer I

Nanotechnologies for Cancer II

Room 103A

Room 103A

Brain Computer Interfaces

Glial Cell Engineering / Neural Progenitor Cell and Tissue Engineering

Neural Engineering

Room 202A

Room 202A

Room 202A Microtechnologies for Cancer II

Room 006D Neuro-rehabilitation Biomechanics

Room 201 Macro/Micro Design for Neurotechnologies: Networked Neural Sensors and Instrumentation

Room 202A

New Frontiers & Special Topics

Global Health I

Global Health II

Room 202B

Room 202B

Biosensors I: Materials and Techniques

Biosensors II: Applications

Room 201 Cells Tissues and Organs on Chip I

Room 008A

Room 201 Cells Tissues and Organs on Chip II

Room 008A

Nanotechnologies for Cancer I

Room 103A

ORTHOPEDIC AND REHABILITATION ENGINEERING

Musculoskeletal Tissue Engineering

Neuro-rehabilitation Biomechanics

Room 007D

Room 201

RESPIRATORY BIOENGINEERING

Engineering Strategies for Lung Transplant & Regeneration

Translational Respiratory Engineering

Mechanobiology in the Respiratory System

Room 008B

Room 008B

Room 008B

Stem Cell Engineering

Mechanobiology of Stem Cells

Directing Stem Cell Differentiation

Stems Cells in Translation Science

Room 007A

Room 007A

Room 007A

Cardiac Regeneration

Room 006D

Adult Stem Cells in Tissue Engineering

Cardiac Muscle and Valve Tissue Engineering

Adult Stem Cells in Tissue Engineering

Muscular, Tendinous, Ligamental Tissue Engineering

Room 001A

Room 001A

Room 001A

Cardiac Regeneration

Directing Stem Cell Differentiation

Room 006D

Room 007A

Cells Tissues and Organs on Chip I

Cells Tissues and Organs on Chip II

Room 008A

Room 008A

Tissue Engineering

Room 001A

Musculoskeletal Tissue Engineering

Room 007D Engineering Strategies for Lung Transplant & Regeneration

Room 008B

TRANSLATIONAL BIOMEDICAL ENGINEERING

Biosensors I: Materials and Techniques

Room 201 Global Health I

Room 202B

OTHER

Biosensors II: Applications

Room 201 Global Health II

Room 202B

Nanotechnologies for Cancer I

Translational Respiratory Engineering

Room 103A

Room 008B

ABioM SIG Special Session: Application towards the Next Generation Therapies and Diagnostics

Undergraduate Research I

Undergraduate Research II

Room 204B

Room 204B

Ballroom A

BMES 2014

217

2014 | October 22 | Wednesday

schedule at-a-glance

WEDNESDAY, October 22, 2014 11:00am – 7:00pm

Registration

HBGCC, Exhibit Hall A

8:30am – 4:30pm

BMES Board of Directors Meeting

HBGCC, Room 102AB

3:30pm – 5:30pm

Meet the Faculty Candidates

HBGCC, West Registration Area

5:30pm – 7:00pm

Welcome Reception

HBGCC, Grotto, River Level

Plenary Sessions Platform Sessions Posters Workshops Student & Early Career Exhibits Special Events General

Affiliate Events: 11:00am – 4:00pm

4:00pm - 5:00pm

6:15pm – 9:00pm

7:00pm – 10:00pm

AIMBE Board

AIMBE Academic Council

Council of Chairs Dinner

Annals of Biomedical

of Directors Meeting

Policy Briefing

& Meeting

Engineering Editorial

Henry B. Gonzales Convention

Henry B. Gonzales Convention

Marriott Rivercenter

Board Dinner

Center, Room 003AB

Center,Room 003AB

Salon J

Marriott Rivercenter, Conference Room 13-14

218

BMES 2014

Schedule at-a-glance

2014 | OCTOBER 23 | Thursday

THURSDAY, October 23, 2014 7:00am – 6:00pm

Registration

HBGCC, Exhibit Hall A

7:00am - 8:00am

Diversity Committee Meeting

HBGCC, Room 003B

7:00am - 8:00am

National Meetings Committee Meeting

HBGCC, Room 003A

8:00am - 9:30am

Platform Session – Thurs 1

HBGCC, 19 concurrent rooms

8:00am - 9:30am

Professional Integrity Workshop

HBGCC, Room 102AB

9:00am - 10:30am

What Do Biomedical Engineers Actually Do?

HBGCC, Room 103A

9:30am – 5:00pm

Exhibit Hall Open

HBGCC, Exhibit Hall A

9:30am – 5:00pm

Poster Session – Thurs

HBGCC, Exhibit Hall A

9:30am – 10:30am

Poster Viewing with Authors & Refreshment Break HBGCC, Exhibit Hall A

Workshops

10:30am – 12:15pm

Plenary Session & State of the Society Pritzker Distinguished Lecturer

HBGCC, Lila Cockrell Theatre

Student & Early Career

12:30pm – 1:45pm

Celebration of Minorities in BME Luncheon

HBGCC, Ballroom A

12:15pm – 1:45pm

Lunch on Your Own

12:45pm – 1:45pm

Medical Devices SIG Business Meeting

HBGCC, Room 003B

1:30pm - 2:30pm

Membership Committee Meeting

HBGCC, Room 003A

1:30pm – 2:45pm

How to Get Your First Job

HBGCC, Room 103A

2:00pm - 3:30pm

Overcoming challenges and obstacles for clinical translation: From bench to bedside

HBGCC, Room 204A

2:00pm - 4:00pm

Resume Review & Critique

HBGCC, Room 012AB

2:00pm - 3:30pm

Platform Session – Thurs - 2

HBGCC - 20 concurrent rooms

2:00pm -6:00pm

BMES-NSF Special Session

HBGCC, Room 004

3:30pm - 4:30pm

Poster Viewing with Authors & Refreshment Break HBGCC, Exhibit Hall A

3:15pm – 4:30pm

Networking Effectively– Social Media & Face-to-Face

HBGCC, Room 103A

4:30pm - 6:00pm

Platform Session – Thurs - 3

HBGCC - 89 concurrent rooms

4:00pm - 7:30pm

Korea-US Joint Workshop in Biomedical Engineering

HBGCC, Ballroom A

5:00pm – 6:15pm

Mock Interview

HBGCC, Room 103A

6:15pm - 7:30pm

Plenary Session: Computational Modeling and Simulation for Medical Devices

HBGCC, Lila Cockrell Theatre

8:00pm – 9:30pm

University Receptions

Marriott Rivercenter and Marriott Riverwalk

Plenary Sessions Platform Sessions Posters

Exhibits Special Events General

Affiliate Events: 12noon – 1:30pm

4:00pm – 5:30pm

6:00pm – 8:00pm

8:00pm – 9:30pm

Cellular and Molecular Bio-

AEMB Annual

AEMB Reception

University Reception

engineering - Editorial Board

Grand Meeting

The Republic of Texas

Marriott Rivercenter

Marriott Rivercenter ,

Henry B. Gonzales Convention

Restaurant

and Marriott Riverwalk

Conference Room 13-14

Center, Room 002AB

BMES 2014

219

friday | October 24 | 2014

schedule at-a-glance

FRIDAY, October 24, 2014

Plenary Sessions

7:00am – 6:00pm

Registration

HBGCC, Exhibit Hall A

7:00am - 8:00am

2015 Annual Meeting Planning Committee Meeting

HBGCC, Room 003A

7:00am - 8:00am

ABioM SIG Business Meeting

HBGCC, Room 102AB

7:00am - 8:00am

Education Committee

HBGCC, Room 003B

8:00am – 9:30am

Platform Sessions - Fri-1-1

HBGCC - 18 concurrent rooms

8:00am - 9:30am

Whitaker International Session

HBGCC, Room 204A

8:30am - 9:30am

BMES Student Chapter—Outstanding Chapter Best Practices

HBGCC, Room 103A

9:30am - 10:30am

BMES Student Chapter Outreach and Mentoring Best Practices

HBGCC, Room 103A

9:30am – 5:00pm

Exhibit Hall Open

HBGCC, Exhibit Hall A

9:30am – 5:00pm

Poster Session – Fri

HBGCC, Exhibit Hall A

9:30am – 10:30am

Poster Viewing with Authors & Refreshment Break

HBGCC, Exhibit Hall A

10:30am – 12noon

Plenary Session NIBIB Lecture

HBGCC, Lila Cockrell Theatre

12noon – 1:30pm

Lunch on Your Own

12noon – 1:30pm

CMBE SIG Business Meeting

HBGCC, Room 003B

12:15pm - 1:30pm

Woman in BME Luncheon

HBGCC, Ballroom A

1:30pm – 2:30pm

International Affairs Committee

HBGCC, Room 003A

2:00pm - 4:00pm

Resume Review & Critique, repeated

HBGCC, Room 102AB

1:45pm - 2:45pm

Platform Session – Fri - 2

HBGCC - 18 concurrent rooms

2:00pm - 4:00pm

Diversity, Health Disparities and Affordable Healthcare

HBGCC, Room 204A

3:00pm - 4:00pm

Platform Session – Fri - 3

HBGCC - 15 concurrent rooms

4:00pm - 5:00pm

Industry Affairs Committee Meeting

HBGCC, Room 003A

4:00pm - 5:00pm

Poster Viewing with Authors & Refreshment Break

HBGCC, Exhibit Hall A

5:15pm - 6:15pm

Plenary Session

HBGCC, Lila Cockrell Theatre

Platform Sessions Posters Workshops Student & Early Career Exhibits Special Events General

Affiliate Events: 9:00am – 10:00am

1:30pm - 3:00pm

AEMB Ethics Session

AIMBE-AEMB Student Public

Henry B. Gonzales Convention

Policy Session

Center, Room 002AB

Henry B. Gonzales Convention Center, Room 002AB

220

BMES 2014

Schedule at-a-glance

2014 | October 25 | saturday

SATURDAY, OCTOBER 24, 2014 7:00am – 2:00pm

Registration

HBGCC, Exhibit Hall A

8:00am – 9:30am

Platform Sessions - Sat-1

HBGCC - 20 concurrent rooms

8:00am - 9:30am

ABioM SIG Special Session

HBGCC, Ballroom A

9:30am – 1:30pm

Exhibit Hall Open

HBGCC, Exhibit Hall A

9:30am – 1:00pm

Poster Session – Sat

HBGCC, Exhibit Hall A

9:30am – 10:30am

Poster Viewing with Authors & Refreshment Break

HBGCC, Exhibit Hall A

10:30am – 12:30pm

Plenary Session Rita Schaffer Young Investigator Lecture & Diversity Award Winner

HBGCC, Lila Cockrell Theatre

12:30pm - 1:30pm